Mx1 in bats

full alignment

D E C M K
R S T F Y
N Q G L V
I A W H P

Input
Alignment
Tree
Codeml
Recombination
Significant sites

Parameters

PoSeiDon v1.1


Fragment_1Fragment_2Fragment_3
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ATG AAT CCT CCT ACA GTG AAG AGG AGT CCT CTT AAA GTG AAA GTC AAA AAT CAT AAT TCG GCC TCT GCG TCC AGT CCT CGG TTA CCA GAT GCT AAG GTG --- --- TCT GAG GAG AAT CTG GAA AAA GGC ACC GAG AGC AGC CTG TGC AGC TAC TAC GAG GAG AAA ATC CGC CCC TGC ATC GAC CTC ATC GAC TCT CTG CGG GCC CTG GGC GTG GAG CAG GAC CTG GCC CTG CCC GCC ATC GCG GTC ATC GGG GAC CAG AGC TCG GGC AAG AGC TCC GTG CTG GAG GCC CTG TCG GGC GTC GCC CTG CCC AGA GGC AGC GGT ATC GTG ACG AGG TGT CCT CTG GTG CTG AAG CTG AGA AAA --- CTG AGG GAC --- GGG GAC GAA TGG AAA GGC AAA GTC AGT TAC AAG GAC CAG GAG ATT GAG ATG TCA GAT GCT TCG GAG GTG GAA GAG GAA ATC AGG AAA GCC CAG GAT GTC ATT GCT GGG GTA GGA ATG GAC ATC AGC CAT GAG CTG ATC AAC CTG GAG GTC AGC TCC CCT CAC GTC CCA GAC CTG ACC CTC ATC GAC CTC CCC GGC ATC ACC AGG GTG GCC CTG GGC AAT CAG CCA GCT GAC ATT GGG TTT CAG ATC AAG AGA CTC ATC AAG AAG TAC ATC CTT AAG CAG CAG ACG ATC AAC TTG GTG GTG GTG CCC AGT AAC GTG GAC ATC GCC ACC ACG GAG GCC TTG AGC ATG GCT CAG GAG GTA GAC CCC GAC GGA GAC AGG ACC ATA GGA ATC CTG ACG AAG CCC GAC CTG GTG GAC AAA GGC ACC GAA AAC AAG GTT GTC GAC GTG GTG CGG AAC CTG GTC TGC CAC CTG AAG AAG GGC TAC ATG ATC GTC AAG TGC AGG GGC CAG CAG GAC ATC CAG GAG CAG CTG AGC TTG ACC GAG GCT CTG CAG AAA GAG AAG GCC TTC TTC GAG GAC CAT CCG CAT TTC AGG AAC CTC CTG GAC GAA GGA AAG GCC ACG ATC CCC TGC CTA GCA GAG AGA CTG ACC ACC GAG CTC ATC GCA CAC ATC TGC AAA TCT CTG CCC CAG TTA GAA AAT GAA ATA AAG GAG AAA CAG CAG AGT ATC ACA GAG GAG TTG CAG ATG TAT GGC ATG GAG ACG CCG GAA GAA GAA AAC GAA AAA ATG TTC TTT CTG ATA GAT AAA CTT AAT GCA TTT AAT CAG GGC ATC CTC ACT TTA ATC CAA GGG GAG GAA ATC GTG GAG AAG AGC AAC ACT CGG CTG TTT ACC AAA ATC CGA AAA GAA TTC AAC AAC TGG AGT AAA GTG ATT GAA AAC AAC TTC CAG GAC GGT TAT GAT GCT GTA TAC AAC GAG ATC TGC AAA TTT GAA AAT CAG TAT CGT GGC AGA GAG CTG CCA GGA TTT GTG AAC TAC AAG ACA TTT GAG AAT ATC ATA AAA CAG CAA ATC AAA ACT CTG GAA GAG CCC GCT GTG GAT ATG CTG CAC ACC GTA ACT CAA ATG GTT TGG CTC GCC TTC ACA GAA GTT TCC CAG AAA AAT TAC AGT GAA TTT TTC AAC CTC TAC AAA GTC TCC AAG TCC AAA ATC GAA GAC ATT AAA ACC GAA CAA GAA AGA GAA GCT GAG AAG TCC ATC CGA CTA CAC TTC CAA ATG GAG CAG ATC GTG TAC TGC CAA GAC ACG ATG TAT CAG AGA TCG TTA CGG AAA ATC AGG GAG AAG GAA AAA GAG AAG GAA --- GAA GAA AGG AAG AGA ACA TTA GGT CGG GCG ATC TGC GAA GAG AGT TCT TCG TAT AAC TCC CTA GAT GAA ATC TTT CAA CAC CTG ATA GCC TAC CAC CAG GAG ACC GGC AAC CGC CTG TCC ACC CAC ATC CCC TTG ACG ATC CAG TTC TTC GTC CTT CAG TCA TTC GGC CAA CAG CTG CAG AAG GCC ATG CTC CAG CTG CTG CAG GAC AAG GAG CAG TAC GAC TGG CTC CTG AAG GAA CGC AGT GAC ACC TGT GAC AAG AGG AAG TTC CTG AAG GAG CAG CAC AGG CGG CTG GTG CAG GCT CGG CAC CAG CTG GCC AAG TTC CCC GGT TAG
--- --- --- --- --- --- --- ATG GGT GTT CCT CAA GTG AAA GTC GAA AGT CAT GGC TCG GCC TCT GCA CCC ATT CCT CAG TTA CCA AAT GCT GAG GTG --- --- CCT GAG AAG AAT CTG GAC AAA GGG GAC GAG ATA AAC CTG TGC AGC TAC TAC GAG GAG AAG GTC CGC CCC TGC ATC GAC CTC ATC GAC TCT CTG CGG GCC CTG GGC GTG GAG CAG GAC CTG GCC CTG CCC GCC ATC GCG GTC ATC GGG GAC CAG AGC TCG GGC AAG AGC TCC GTG CTG GAG GCC CTG TCG GGC GTC GCC CTC CCC AGA GGC AGC GGT ATC GTC ACG AGG TGT CCT CTG GTG CTG AAG CTG AGA AAA --- GTG ACG GAC --- GGA GAT GGA TGG AAA GGC AAA GTC AGT TAC CAG GAC GTG GAG ATT GAG ATT TCA GAT CCT TTG GCG GTG GAA AAG GAA ATC AGT AAA GCC CAG GAT GTC ATT GCT GGG GTA GGA GTG GAC ATC AGC CAC GAG CTG ATC AAC CTG GAG GTC AGC TCC CCT CAC GCC CCA GAC CTG ACC CTC ATC GAC CTC CCC GGC ATC ACC AGG GTG GCC GTG GGC AAC CAG CCC GCT GAC ATT GGG CGT CAG ATC AAG GCG CTC ATC AGG AAG TAC ATC CGG AAG CAG GAG ACA ATC AAC CTG GTG GTG GTG CCC AGC AAC GTG GAC ATC GCC ACC ACG GAG GCC CTG AGC ATG GCT CAG GAG GTG GAC CCC GAC GGA GAC AGG ACC ATA GGC ATC CTG ACG AAG CCC GAC CTG GTG GAC AAG GGC ACC GAA CAC AGG GTC GTG GAC GTG GTG CGG AAC CTG GTT TGC CAA CTG AAG AAG GGC TAC ATG ATC GTC AAG TGC AGG GGC CAG CAG GAC ATC CAG GAC CAG CTG AGC CTG GCC GAG GCT CTG CGC AAA GAG AAG GCC TTC TTC GAG GAC AAT CCG TAT TAC AGG GAG CTC CTG GAG GAA GGG AAG GCC ACG ATC CCC TGC CTA GCG GAG AGA CTG ACC GCC GAG CTC ATC GCG CAC ATC TGT AAA TCT CTG CCC CGG TTA GAA AAC GAA ATA AAG GAG AAA CAG CAG ACT ATA ACG GAG GAG TTA CAA AAG TAT GGC ACA GAG ATA CCG GAA GAC GAA AGT GAA AAA ATG TTC TTT CTG ATC GAG AAA ATT AAT GCA TTT AAT CAG GGC ATC CGC GCT TTA ACG CAA GCT GAG GAA TTA GTG GGG AAG AAG GAC ACT CGG CTG TTT ACC AAA ATC CGA AAT GAG TTC AAC AAC TGG AGT AAA CTG ATT GAG AAA AGC TTC CAG ATG GGT ATC TGT GCT ATG CAG AAC GAG CTC TAT AAA TTT GAA AAT CAG TAT CGT GGC AGA GAG CTG CCA GGA TTT GTG AAC TAC AAG ACA TTT GAG AGT ATC ATA AAA CAG CAA ATC AAA ACC CTG GAA GAG CCC GCT GTG GAC ATG CTG CAC GCC GTA ACT GAA ATG ATT TGG CAA GCC TTC ACA GAC GTT TCC CAG AAA AAT TTC AGT GAA TTT TTC AAC CTC TAC AGA GTC TCC AAG TCC AAA ATC GAA GAC ATT AAA ACC GAA CAA GAA AGA GAG GCC GAG AAG TCC ATC CGA CTT CAC TTC CAA ATG GAG CAG ATG GTG TAC TGC CAA GAC CAG GTG TAT CGG AAA TCA TTA CAG ATA GTC AGG GAG AAG GAG AAG GAG AAG GTT GAA CAA TAC AAG AAT AAA TCA AGA GTT TTG GAC CTT GAA CAG AGT TTT CCA AAT GTC ACC CCC CTA GAT GAA ATC CTT CCA CAC CTG ACA GCC TAC CGC CAG GAC GCC AGC AAC CGC CTG TCC ACC CAC ATC CCC TTG GTC ATC CAG TAC TTC CTG CTC CAG TCA TTC GGC CGC CAG CTG GAG AAG TCC ATG CTC CAG CTG CTG CAG GAC AAG GAG CAG TAC GGC TGG CTC CTG AGG GAA CGC AGC GAC ACC TGC GAG AAG AGG AAG CTC CTG AAG GAG CAG CAC CGG CGG CTG GTT GCG GCC CGG CAC CGG CTG GCC CAG TTC CCC GGT TAG
--- --- --- --- --- --- --- ATG GGT GTT CCT CAA GTG AAA GTC CAA GGT CAT AGC TCG GAC CTT GCA TCC GCG CCT CAG TTA CCA AAT GCT GAG GTG --- --- CCT GAG AAG AAT CTA AAA AAA GGG GAA GAG ACA GAC CTG TGC AGC CAC TAC GAG GAG AAG GTC CGC CCC TGC ATC GAC CTC GTC GAC TCT CTG CGG GCC CTG GGC GTG GAG CAG GAC CTG GCC CTG CCC GCC ATC GCG GTC ATC GGG GAC CAG AGC TCG GGC AAG AGC TCG GTG CTG GAG GCC CTG TCG GGC GTT GCC CTC CCC AGA GGC AGC GGC ATC GTC ACC AGG TGT CCT CTG GTG CTG AAG CTG AGA CAA --- GCG AGG GAC --- GGC GGT GCC TGG AAA GGC AAA GTC AGT TAC CAG GAC GAG GAG GTT GAG ATT CCA GAC CCT TCG GCG GTG GAG AGG GAA ATC CGG AAA GCC CAG GAC GCC ATG GCT GGG GTA GGA GTG GGC ATC AGC CAC GAG CTG ATC ACC CTG GAG GTC AGC TCC CCT CAC GCC CCG GAC CTG ACC CTC ATC GAC CTC CCC GGC ATC ACC AGG GTG GCA GTG GGC AAC CAG CCC GCT GAC ATC GGG TGG CAG ATC AAG GCG CTC ATC AGG AAG TAC ATC CAG AAG CAG GAG ACC ATC AAC CTG GTG GTG GTG CCC AGC AAC GTG GAC ATC GCC ACC ACG GAG GCA CTG AGC ATG GCT CAG GAG GTG GAC CCC GAC GGA GAC AGG ACC ATC GGC ATC CTG ACG AAG CCC GAC CTG GTG GAC AAA GGC ACC GAA CAC AGG GTC GTG GAC GTG GTG CGG AAC CTG GTT TGC CCC CTG AAG AAG GGC TAC ATG ATC GTC AAG TGC CGG GGC CAG CAG GAC GTC CAG GGC CAG CTG AGT CTG GCC GAG GCT CTA CGC AAA GAG AAG GCC TTC TTC GCG GAC CAT CCG TCT TAC AGG GAC CTC CTG GAG GAA GGG ATG GCC ACG ATC CCC TGC CTC GCG GAG AGA CTG ACG GCC GAG CTC ATC GCG CAC ATC TGT AAA TCT CTG CCC TGG TTA GAA AAC GAA ATA AAG GAG AAA CAG CAG AAT ATC ACA GAG GAG TTA CAA AAG TAT GGC ACA GAG ATA CCG GAA GAC GAA AGT GAA AAA ATG TTC TTT CTG ATA GAT AAA ATT AAC GCG TTT AAC CAG GGC ATC CTC GCT TTA ACG CAA GCC GAG GAG TTA GTG GGG AAG AAT GAC ACT CGG CTG TTT ACC AAA ATC CGA AAT GAG TTC AAC AGC TGG AGT AAA ATG ATT GAC AGA AGC TTC CAG GCG GGT TAC AGT GCT CTG GAG AGC GAG ATC TTG AAA TTT GAA AAT CAG TAC CGC GGC AGA GAG CTG CCG GGA TTC GTG AAC TAC AAG ACA TTC GAG AGC ATC GTA AAA CAG CAG ATG AAG ACC CTG GAG GAG CCC GCT GTG GAA ATG CTG CAC ACC GTG ACC GAG ATG GTG TGG CGA GCC TTC GCA GAC GTT TCC CAG AAA CAC TTC AAT GAA TTT TTC AAC CTC TAC AGA GTC TCC AAG TCC AAA ATT GAA GAC CTT AAA ACC GAA AAG GAA AGA GAA GCC GAG AAG TTC ATC CGA ATT CAC TTC GAG ATG GAG CAG ATG GTG TAC TGC CAG GAC CAG GTG TAC CAG AGA TCA TTA CAG AAA GTC AGG GAG AAG GAG AAT GAA GAA CAA --- --- AAC AAG AAT AAA TCA AGA GTT TTG GAC CTT GTA CAG AGT TCT CCA GAC AGC TCG CCG CTC GGT GAA ATC CTT CCA CAT CTG ACG GCC TAC CGC CAG GAC GCC CGG GAC CGC CTG GCC ACC CAC ATC CCC TTG GTC ATC CAG TTC TTC GTG CTG CAG TCG TTC GGC CAG CAG CTG CAG AAG TCC ATG CTC CAG CTG CTA CAG GAC AAG GAG CAG TAC GGC TGG CTC CTG AGG GAA CGC AGC GAC ACC TGC GAG AAG AGG AAG CGC CTG AAG GAG CAG CAC CGG CGG CTG GTG CAG GCT CGG CAC CGG CTG GCC CAG TTC CCC GGT TAG
--- --- --- --- --- --- --- ATG GGT GTC CCT CAA GGG AAA ATC CAA AAC CAT GAT TTG GCC TTT GCA GCC AGT CCT CCG TTA CCA AAT ACT GAG GTG --- --- TCT GAG AAG AAT CCG GAA AAA AGG GAA GAG AGC AGC CTA TGC AGC CAC TAC GAG GAG AAG GTC CGC CCC TGC ATC GAC CTC ATC GAC TCC CTG CGG GCC CTG GGC GTG GAG CAG GAC CTG GCC CTG CCC GCC ATT GCG GTC ATC GGG GAC CAG AGC TCG GGC AAG AGC TCC GTG CTG GAG GCC CTG TCC GGC GTC GCC CTC CCC AGG GGC AGC GGT ATC GTC ACA AGG TGT CCT CTG GTG CTG AAG CTG AGA AAA --- GTG AGG GAC --- GGA GAC GAA TGG AAA GGC AAA GTC AGT TAC CAC GAC GTG GAG GTT GAG ATT TCA GAT CCT TTG GAG GTG GAA AAG GAA ATC AGT AAA GCC CAG GAT GCC ATT GCA GGG GTA GGA ATG GAC ATC AGC CAT GAG CTG ATC GAC CTG GAG GTC AGC TCC CCT CAC GTC CCA GAC CTG ACC CTC ATC GAC CTC CCC GGC ATC ACC AGG GTG GCC GTG GGC AAC CAG CCA GCT GAC ATT GGG CAG CAG ATC AAG AAA CTC ATC AGG AAG TAC ATC CTT AAG CAG GAG ACA ATC AAC TTG GTG GTG GTA CCC AGC AAC GTG GAC ATC GCC ACC ACG GAG GCC TTG AGC ATG GCT CAG GAG GTG GAC CCC GAT GGA GAC AGG ACC ATA GGA ATC CTG ACG AAG CCA GAC CTG GTG GAC AAA GGC ACC GAA AAC AGG GTC GTG GAC GTG GTG CAG AAC CTG GTC TGC CAC CTG AAG AAG GGC TAC ATG ATC GTC AAG TGC AGG GGC CAG CAG GAC ATC CAG GAC CAG CTG AGC CTG GCC GAG GCT CTG CAG AAG GAG AAG GCC TTC TTT GAG GAC CAT TCG CAT TTC AGG GTC CTC CTG GAG GAA GGG AAG GCC ACG ATC CCC TGC CTA GCA GAG AGA CTG ACC GCT GAG CTC ATC ACA CAC ATC TGT AAA TCT CTG CCC TGG TTA GAA AAC GAA ATA AAG GAG AAA CAG CAG AAA ATA ACA GAG GAG TTA CAA AAG TAT GGC ACA GAG ATA CCA GAA GAC GAA AAT GAA AAA ACG TTC TTT CTG ATG GAT AAA ATT AAT GCA TTT AAT CAG GCC ATC CTC GCT TTA GTA CAA GGG GAG GAA ATC GTG GAG AAC AAC GAC ATT CGG CTG TTT ACC AAA ATC CGG AAT GAG TTC AAC AAG TGG AGT AAA GTG ATT GAA AAA AAC TTC CAG GAG GGT TAC AGT GCT ATA CAC AAC GAG ATC TGG AAA TTT GAA AAT CAG TAT CGT GGC AGA GAG CTG CCA GGA TTC GTG AAC TAC AAG ACA TTT GAG AGC ATC ATA AGA CAG CAA ATC AAA ACA CTG GAA GAG CCC GCT GTG GAT ATG CTG CAC ACC GTA GCT GAT AAG GTT TGG CTT GCC TTC GCA GAA GTT GCC CAG AAA AAT TAC AAT GAA TTT TTC AAC CTC CAC AAA GTC TCC AAG TCC AAA ATT GAA GAC ATC AAA ACC GAA CAA CAA AAA GAA GCC GAG AAG TCC ATC CGA CTT CAC TTC CAA ATG GAG CAG ATC GTG TAC TGC CAA GAT CAG ATG TAC CAG AGT TCA TTA CAG AAA ATC AGG GCG AAG GAG AAG GAG AAG GAA --- --- GAA GAA ATG AAG AAG AAA TTT AAT TGT TTG AAC CTT CAA CAG AGT TCA AGT AAC TCC CTA GAT GAA ATC TTT CAA CAC CTG ACA GCC TAC CAC CAG GAG ACC AGC AAA CGC CTG TCC ACC CAC ATC CCC TTG GTC ATC CAG TTC TTC ATC CTT CGG TCA TTC GGC CAG AAG CTG CAG ATG GCC ATG CTC CAG CTG CTG CAG GAC AAG GAG CAG TAC GAC TGG CTC CTG AAG GAA CGC AGT GAC ACC TGC GAC AAG AGG AAG TTC CTG AAG GAG CAG CAC AAG CGG CTG GTG GAG GCT CGG CAC GAG CTG GCC AAG TTC ACC TGC TAG
--- --- --- --- --- --- --- --- --- --- --- --- ATG GAA ACA GCA AGT CCT GAT TCC ACC CCT GCA CCC AGT CAT CCC TTA CCA AAT GGA GAT GCT GTT ACG CCG GAG GGA AAT CTG GAG ACG ACG TTG GAG AAT AGC CTG TGC AGC CAG TAC GAG GAG AAG GTG CGC CCC TGC ATC GAC CTC ATC GAC TCC CTG CGG GCC CTG GGC GTG GAG CAG GAC CTG GCC CTG CCC GCC ATC GCC GTC ATC GGG GAC CAG AGC TCG GGA AAG AGC TCC GTG CTG GAG GCG CTG TCT GGT GTC TCC CTC CCC AGA GGC AGC GGT ATT GTT ACA AGA TGT CCC CTG GTG CTG AAA CTG AGA AAA --- CTT AGG CAT --- GAT GAT GAG TGG AAA GGC AAA GTC ACT TAC CGA GAC CTG GAG ATT GAG CTT TCT ACT GCT TCG GAG GTA GAA CAG GAA ATC AGG AAA GCC CAG AAT GTC ATT GCT GGG GAA GGT GTG GGA ATC AGT CAA GAG CTA ATT AAT CTG GAG GTC AGC TCC CCT CAC GTG CCA GAT CTG ACC CTG ATA GAC CTT CCT GGC ATC ACC AGG GTG GCT GTG GGG AAT CAG CCA GCT GAC ATC GGA CGT CAG ATT ATA GCA CTC ATC AAG AAG TAC ATC CTG AGG CAA CAG ACC ATC ATG TTG GTG GTG GTG CCC AGT AAC GTG GAC ATC GCC ACC ACA GAG GCG CTG AGC ATG GCT CAG GAG GTG GAC CCC GAT GGA GAC AGG ACC ATA GGG ATC CTG ACA AAG CCC GAC CTG GTG GAC AGA GGC ACG GAA GAC AAG GTC GTT GAC GTG GTG CGA AAC CTC GTC TAC CAC CTG AAG AAG GGC TAC ATG ATC GTC AAG TGC CGG GGC CAA CAG GAC ATC CAG TAC CAG ATG AGC CTG TCC AAG GCC CTG CAG AGA GAG AGG GCC TTC TTC GAG GAC CAT CCT TAT TTC AGG GAT CTC CTG GAG GAG GGA AAG GCC ACG ATC CCC TGC CTG GCA GAA AGA CTG ACC AAT GAG CTC ATC GCA CAC ATC AGT AAA TCT CTG CCC CTG TTA GAA AAT CAA ATA AAG GAG AAC CAG CAG AGT ATA ACA GAG CAG TTG CAG AAG TAT GGC ATG GAC ATC CCG GAA GAA GAA ACT GAG AAA ATG TTC TTT CTG ATT GAC AAA ATC AAT GCA TTT AAT CAG GAC ATC CAA GCC TTA GTA GAG GGG GAG GAA TCT GTG TGG GGC GAC GAC AGT CGG CTG TTC ACC AGA ATC CGG ATG GAG TTC GGC AAG TGG AGC ATT GAG ATC GAA AAG AGT TTC CAG AGA GGT TAT GAT GAT ATT TTT AGA CAG ATC AGG AAA TTT GAA AAT CAG TAT CGC GGC AGA GAG CTG CCA GGG TTC GTG AAT TAC AAG ACG TTT GAG ACG ATC ATA AAG AAG CAA GTG AAG ACC CTG GAG GAG CCG GCG GTG GAA ATG CTG CAT AAG ATC ACC GAT ATG GTC CGG CTT GCC TTC GCA GAT GTT TCC AAG AAA AAT TAT GAG GAG TTT TTC AAC CTT TTC AGA ACC TGC AAG TCC AAA ATT GAA GAC ATT AAG TCA GAA CAA GAA AAG GAA GCG GAG AAG TCC ATC CGA CTG CAC TTC CAA ATG GAG CAG ATT GTC TAC TGC CAG GAC CAA GCG TAC CGG GCT GCG CTG CAG AAG ATC CGA GAG AAG GAA TCT AAA GAA GAG --- --- AAG AAG GGG AGT TCT CGC GAG CAG ACG CCC TCT CTG GAG GAT CCT TTG ACT TGC TCC CTC ATT GAA ATC CTC CAA CAC CTG ATG GCC TAC CGC CTG GAG GCC TGC AAC CGC CTG TCC AGC CAC ATC CCT CTG GTC ATC CAG TTC TTC ATC CTC CAA TCG TAC GGG CAG CAG CTG CAG AAG GCC ATG CTC CAG CTG CTG CAG GAC AAG GAG AAG TAC GAC TGG CTC CTC AAG GAG CAC AGC GAC ACC AGC GAC AAG AGG AAG TTC CTG AAG GAG CGG CTG GCG CGG CTG ACC AAG GCC CGG CGC CGG CTG GCC CAG TTC CCG GGC TAG
--- --- --- --- --- --- --- --- --- --- --- --- ATG GAA ACA GCA ACT CCT GAT TCC ACC CCT GCA TCC AGT CAT CCC TTA CCA AAT GGA GAT GCT GTT GAG CCG GAG GGA AAT CTG GAG ACA ACG TTG GAG AAT AGC CTG TGC AGC CAG TAC GAG GAG AAG GTG CGC CCC TGC ATC GAC CTC ATT GAC TCC CTG CGG GCC CTG GGT GTG GAG CAG GAC CTG GCC CTG CCT GCC ATC GCC GTC ATC GGG GAC CAG AGC TCG GGC AAG AGC TCC GTG CTG GAG GCG CTG TCT GGT GTC TCC CTC CCC AGA GGC AGC GGT ATT GTT ACA AGA TGT CCC CTG GTG CTG AAA CTG AGA AAA --- CTT AGG CAT --- GAT GAT GAG TGG AAA GGC AAA GTC ACT TAC CGG GAC CTG GAG ATT GAT CTT TCA ACT GCT TCG GAG GTA GAA CAG GAA ATC AGG AAA GCC CAG AAT GTC ATT GCT GGG GAA GGT GTG GGA ATC AGT CAA GAG CTA ATT AAT CTG GAG GTC AGC TCC CCT CAC GTG CCA GAT CTG ACC CTG ATA GAC CTT CCT GGC ATC ACC AGG GTG GCT GTG GGC AAT CAG CCA GCT GAC ATC GGA CGT CAG ATT ACA GCA CTC ATC AAG AAG TAC ATC CTG AGG CAA CAG ACC ATC ATG TTG GTG GTG GTG CCC AGT AAC GTG GAC ATC GCC ACC ACA GAG GCG CTG AGC ATG GCT CAG GAG GTG GAC CCC GAT GGA GAC AGG ACC ATA GGG ATC CTG ACA AAG CCC GAC CTG GTG GAC AGA GGC ACG GAA GAC AAG GTC GTT GAC GTG GTG CGA AAC CTC GTC TAC CAC CTG AAG AAG GGC TAC ATG ATT GTC AAG TGC CGG GGC CAG CAG GAC ATC CAG TAC CAG ATG AGC CTG TCC AAG GCC CTG CAG AGG GAG AGG GCT TTC TTT GAG GAC CAT CCG TAT TTC AGG GAT CTC CTG GAG GAG GGA AAG GCC ACA ATC CCC TGC CTG GCA GAA AGA CTG ACC AAT GAG CTC ATC GCA CAC ATC AGT AAA TCT CTG CCC CTG TTA GAA AAT CAA ATA AAG GAG AAC CAG CAG AGC ATA ACA GAG CAG TTG CAG AAG TAT GGC ATG GAC ATC CCG GAA GAA GAA ACG GAG AAA ATG TTC TTT CTG ATT GAC AAA GTC AAT GCA TTT AAT CAG GAC ATC CAA GCT CTA GTA GAG GGG GAG GAG TCT GTG TTT GGC GAC GAC AGC CGG CTG TTC ACC AGA ATC CGG ATG GAG TTC GGC AAG TGG AGC ATT GAG ATC GAA AAG AGT TTC CAG AGA GGT TAT GAC GAT ATT TTT AGA CAG ATC AGG AAA TTT GAA AAT CAG TAT CGC GGC AGA GAG CTG CCA GGG TTC GTG AAT TAC AAG ACG TTT GAG ACG ATC ATA AAG AAG CAA GTG AAG ACC CTG GAG GAG CCG GCG GTG GAA ATG CTG CAT AAG ATC ACC GAT ATG GTC CGG CTT GCC TTC ACA GAT GTG TCC AAG AAA AAT TAT GAG GAG TTT TTC AAC CTT TTC AGA ACC TGC AAG TCC AAA ATT GAA GAC ATT AGG TCA GAA CAA GAA AAG GAA GCG GAG AAG TCC ATC CGA CTG CAC TTC CAA ATG GAG CAG ATT GTC TAC TGC CAA GAC CAA GCG TAC CGG GCT GCG CTG CAG AAG ATC CGA GAG AAG GAA TCA AAA GAA GAG --- --- AAG AAG GGG ATT TCT CTC CAG CAG ACG TCC TCT CTG GCG GAT CCT TTG ACT TGC TCC CTC GCT GAA ATC CTC CAA CAC CTG ATG GCC TAC CGC CTG GAG GCC AGC AAC CGC CTG TCC AGC CAC ATC CCT CTG GTC ATC CAG TTC TTC ATC CTC CGG TCG TAC GGG CAG CAG CTG CAG AAG GCC ATG CTC CAG CTG CTG CAG GAC AAG GAG AGG TAC GAC TGG CTC CTC AAG GAG CAC AGC GAC ACC AGC GAC AAG AGG AAG TTC CTG AAG GAG CGG CTG GCG CGG CTC ACC AAG GCC CGG CGC CGG CTG GCC CAG TTC CCG GGC TAA
--- --- --- --- --- --- --- --- --- --- --- --- ATG GAA ACA GCA ACT CCT GAC TCC ACC CTT GCA TCC AGT CAT CCC TTA CCA AAT GGA GAT GCT GTT ACG CCG GAG GGA AAT CTG GAG ACA ACG TTG GAG AAT AGC CTG TGC AGC CAG TAC GAG GAG AAG GTG CGC CCC TGC ATC GAC CTC ATC GAC TCC CTG CGG GCC CTG GGC GTG GAG CAG GAC CTG GCC CTG CCC GCC ATC GCC GTC ATC GGG GAC CAG AGC TCG GGC AAG AGC TCC GTG CTG GAG GCG CTG TCT GGT GTC TCC CTC CCC AGA GGC AGC GGT ATT GTT ACA AGA TGT CCC TTG GTG CTG AAG CTG AGA AAA --- CTT AGG CAT --- GAT GAT GAG TGG AAA GGC AAA GTC ACT TAC CGG GAC CTG GAG ATT AAC CTT TCA ACT GCT TTG GAG GTA GAA CAG GAA ATC AGG AAA GCC CAG AAT GTC ATT GCT GGG GAA GGT GTG GGA ATC AGT CAA GAG CTA ATT AAT CTG GAG GTC AGC TCC CCT CAT GTG CCA GAT CTG ACC CTG ATA GAC CTT CCT GGC ATC ACC AGG GTG GCT GTG GGC AAT CAG CCA GCT GAC ATC GGA CGT CAG ATT ACA GCA CTC ATC AAG AAG TAC ATC CTG AGG CAA CAG ACC ATC ATG TTG GTG GTG GTG CCC AGT AAC GTG GAC ATC GCC ACC ACA GAG GCG CTG AGC ATG GCT CAG GAG GTG GAC CCC GAT GGA GAC AGG ACC ATA GGG ATC CTG ACA AAG CCC GAC CTG GTG GAC AGA GGC ACG GAA GAC AAG GTC GTT GAC GTG GTG CGA AAC CTC GTC TAC CAC CTG AAG AAG GGC TAC ATG ATC GTC AAG TGC CGG GGC CAA CAG GAC ATC CAG TAC CAG ATG AGC CTG TCC AAG GCC CTG CAG AGA GAG AGG GCC TTC TTC GAG GAC CAT CCG TAT TTC AGG GAT CTC CTG GAG GAG GGA AAG GCC ACC ATC CCC TGC CTG GCA GAA AGA CTG ACC AAT GAG CTC ATC GCA CAC ATC AGT AAA TCT CTG CCC CTG TTA GAA AAT CAA ATA AAG GAG AAC CAG CAG AGT ATA ACA GAG CAG CTG CAG AAG TTT GGC ATG GAC ATC CCG GAA GAA GAA ACT GAG AAG ATG TTC TTT CTG ATT GAC AAA ATC AAT ACA TTT AAT CAG GAC ATC CAA GCT TTA GTA GAG GGG GAG GAA TCT GTG TGG GGC GAC AAC AGT CGG CTG TTC ACC AGA ATC CGG ATG GAG TTC GGC AAG TGG AGC ATT GAG ATC GAA AAG AGT TTC CAG AGA GGT TAT GAC GAT ATT TTT AGA CAG ATC AGG AGA TTT GAA AAT CAG TAT CGC GGC AGA GAG CTG CCA GGG TTC GTG AAT TAC AAG ACG TTT GAG ACG ATC ATA AAG AAG CAA GTG AAG ACC CTG GAG GAG CCG GCG GTG GAA ATG CTG CAT AAG ATC ACC GAT ATG GTC CGG CTT GCC TTC GCA GAT GTT TCC AAG AAA AAT TAT GAG GAG TTT TTC AAC CTT TTC AGA ACC TGC AAG TCC AAA ATT GAA GAC ATT AAG TCA GAA CAA GAA AAA GAA GCG GAG AAG TCC ATC CGA CTG CAC TTC CAA ATG GAG CAG ATT GTC TAC TGC CAA GAC CAA GCG TAC CGG GCT GCG CTG CAG AAG ATC CGA GAG AAG GAA TCC AAA GAG CAG --- --- --- AAG GGG AGT TCT CGC GAG CAG ACG TCC TCT CTG GAG GAT CCT TTG ACT TGC TCC CTC GCT GAA ATC CTC CAA CAC CTG TTG GCC TAC CGC CTG GAG GCC AGC AAC CGC CTG TCC AGC CAC ATC CCT CTG ATC ATC CAG TTC TTC ATC CTC CGG TCG TAC GGG CAG GAG CTG CAG AAG GCC ATG CTC CAG CTG CTG CAG GAC AAG GAG AAG TAC GAC TGG CTC CTC AAG GAG CAC AGC GAC ACC AGC GAC AAG AGG AAG TTC CTG AAG GAG CGG CTG GCG CGG CTG ACC AAG GCC CGG CGC CGG CTG GCC CAG TTC CCG GGC TAA
--- --- --- --- --- --- --- --- --- --- --- --- ATG GAA ACA GCA ACT CCT GAT TCC ACC CCT GCA TCC AGT CAT CCC TTA CCA AAT GGA GAT GCT GTT GCG CCG GAG GGA AAT CTG GAG ACA ACG TTG GAG AAT AGC CTG TGC AGC CAG TAC GAG GAG AAG GTG CGC CCC TGC ATC GAC CTC ATC GAC TCC CTG CGG GCC CTG GGC GTG GAG CAG GAC CTG GCC CTG CCC GCC ATC GCC GTC ATC GGG GAC CAG AGC TCG GGC AAG AGC TCC GTG CTG GAG GCG CTG TCT GGT GTC TCC CTC CCC AGA GGC AGC GGT ATT GTT ACA AGA TGT CCC CTG GTG CTG AAA CTG AGA AAA --- CTT AGG CAT --- GAT GAT GAG TGG AAA GGC AAA GTC ACT TAC CGG GAC CTG GAG ATT GAT CTT TCA GCT GCT TCG GAG GTA GAA CAG GAA ATC AGG AAA GCC CAG AAT GTC ATT GCT GGG GAA GGT GTG GGA ATC AGT CAA GAG CTA ATT AAT CTG GAG GTC AGC TCC CCT CAC GTG CCA GAT CTG ACC CTG ATA GAC CTT CCT GGC ATC ACC AGG GTG GCT GTG GGC AAT CAG CCA GCT GAC ATC GGA CGT CAG ATT ACA GCA CTC ATC AAG AAG TAC ATC CTG AGG CAA CAG ACC ATC ATG TTG GTG GTG GTG CCC AGT AAC GTG GAC ATC GCC ACC ACA GAG GCG CTG AGC ATG GCT CAC GAG GTG GAC CCC GAT GGA GAC AGG ACC ATA GGG ATC CTG ACA AAG CCC GAC CTG GTG GAC AGA GGC ACG GAA GAC AAG GTG GTT GAT GTG GTG CGA AAC CTC GTC TAC CAC CTG AAG AAG GGC TAC ATG ATC GTC AAG TGC CGG GGC CAA CAG GAC ATC CAG TAC CAG ATG AGC CTG TCC AAG GCC CTG CAG AGA GAG AGG GCC TTC TTC GAG GAC CAT CCG TAT TTC AGG GAT CTC CTG GAG GAG GGA AAG GCC ACG ATC CCC TGC CTG GCA GAA AGA CTG ACC AAT GAG CTC ATC GCA CAC ATC AGT AAA TCT CTG CCC CTG CTA GAA AAT CAA ATA AAG GAG AAC CAG CAG AGT ATA ACA GAG CAG TTG CAG AAG TAT GGC ATG GAC ATC CCG GAA GAA GAA ACT GAG AAA ATG TTC TTT CTG ATT GAC AAA ATC AAT ACA TTT AAT CAG GAC ATC CAA GCT TTA GTA GAG GGG GAG GAA TCT GTG TGT GGC GAC AAC AGT CGG CTG TTC ACC AGA ATC CGG ATG GAG TTC GGC AAG TGG AGC ATT GAG ATC GAA AAG AGT TTC CAG AGA GGT TAT GAC GAT ATT TTT AGA CAG ATC AGG AAA TTT GAA AAT CAG TAT CGC GGC AGA GAG CTG CCA GGG TTC GTG AAT TAC AAG ACG TTT GAG ACG ATC ATA AAG AAG CAA GTG AAG ACC CTG GAG GAG CCG GCG GTG GAA ATG CTG CAT AAG ATC ACC GAT ATG GTC CGG CTT GCC TTC ACA GAT GTT TCC AAG AAA AAT TAT GAG GAG TTT TTC AAC CTT TTC AGA ACC TGC AAG TCC AAA ATT GAA GAC ATT AAG TCA GAA CAA GAA AAA GAA GCG GAG AAG TCC ATC CGA CTG CAC TTC CAA ATG GAG CAG ATT GTC TAC TGC CAA GAC CAA GCG TAC CGG GGT GCG CTG CAG AAG ATC CGA GAG AAG GAA TCC AAA GAG CAG --- --- --- AAG GGG AGT TCT CGC GAG CAG ACG TCC TCT CTG GAG GAT CCT TTG ACT TGC TCC CTC GCT GAA ATC CTC CAA CAC CTG TTG GCC TAC CGC CTG GAG GCC AGC AAC CGC CTG TCC AGC CAC ATC CCT CTG ATC ATC CAG TTC TTC GTC CTC CGG TCG TAC GGG CAG CAG CTG CAG AAG GCC ATG CTC CAG CTG CTG CAG GAC AAG GAG AAG TAC GAC ATG CTC CTC AAG GAG CAC AGC GAC ACC AGC GAC AAG AGG AAG TTC CTG AAG GAG CGG CTG GCG CGG CTG ACC AAG GCC CGG CGC CGG CTG GCC CAG TTC CCG GGC TAA
--- --- --- --- --- --- --- --- --- --- --- --- ATG GAA ACG GCA ACT CCC GAC TCC ACC TCC GCG TCT GGC CAG CCC TTA CCC AAT GGA GAT GCT GTT GGG CCA GAG GTA AAT CCG GAG GCA ATG CTG GAG ACG AGC TTG TGC AGC CAG TAC GAG GAG AAG GTG CGC CCC TGC ATC GAC CTC ATC GAC TCC CTG CGG GCC CTG GGC GTG GAG CAG GAC CTG GCC CTG CCC GCC ATC GCC GTC ATC GGG GAC CAG AGC TCG GGC AAG AGC TCA GTG CTG GAG GCG CTG TCT GGT GTC TCC CTC CCC AGA GGC AGC GGT ATT GTT ACA AGA TGC CCC CTG GTG CTG AAA CTG AGA AAA --- CTT AGG CAT GAT GAT GAT GAG TGG AAA GGC AAA GTC ACT TAC CGG GAC ATG GAG ATC AAT CTT TCA GCC GCT TCC GAG GTA GAA CAG GAA ATC AGG AAA GCC CAG AAT GTC ATT GCT GGG GAA GGT GTG GGA ATC AGT CAT GAG CTA ATT AGT CTG GAG GTC AGC TCC CCT CAC GTG CCA GAT CTG ACC CTG ATA GAC CTT CCT GGC ATC ACC AGG GTG GCT GTG GGC AAT CAG CCA GCT GAC ATC GGA CGT CAG ATT ACA ACA CTC ATC AAG AAG TAC ATC CTG AGG CAG CAG ACC ATC ATG TTG GTG GTG GTG CCC AGT AAC GTG GAC ATC GCC ACC ACA GAG GCG CTG AGC ATG GCT CAG GAG GTG GAC CCC GAA GGA GAC AGG ACC ATA GGG ATC CTG ACA AAG CCC GAC CTG GTG GAC AGA GGC ACC GAA GAC AGA GTC GTT GAC GTG GTG CGA AAC CTC GTC TAC CAC CTG AAG AAG GGC TAC ATG ATC GTC AAG TGC CGG GGC CAA CAG GAC ATC CAG TAC CAG ATG AGC CTG TCC AAG GCT CTG CAG AGA GAG AGG GCC TTC TTC GAG GAC CAT CCG TAT TTC AGG GAT CTC CTG GAG GAG GGA AAG GCC ACC ATC CCC TGC CTG GCA GAA AGA CTG ACC AAT GAG CTC ATT GCA CAC ATC AGT AAA TCT CTG CCC CTG TTA GAA AGT CAA ATA AAG GAG AAC CAG CAG AGT ATT ACA GAG CAG TTG CAG AAG TAT GGC ATG GAC ATC CCG GAA GAA GAA ACG GAG AAA ATG TTC TTT CTG ATT GAC AAA ATT AAT ACA TTT AAT CAG GAC ATC CAC GCT TTA GTA GAC GGG GAG GAA TCT GTG GGG GGC AAC GAC AGT CGG CTG TTC ACC AAA ATC CGG ATG GAG TTC TGC AAG TGG AGC CTT GAG ATC GAA AAG AAT TTC CAG AGA GGT TAT GAA GAT ATT TTT AGA CAG ATC AAG AAA TTT GAA AAT CAG TAT CGT GGC AGA GAG CTG CCA GGG TTC GTG AAT TAC AGG ACG TTC GAG ACG ATC ATC AAG AAG CAG GTG AAG ACG CTG GAG GAG CCG GCG GTG GAA ATG CTG CAC AAG ATC ACC GAT ATG GTC CGG CTT GCC TTC ACA GAT GTT TCC AAG AAA AAT TAC GAG GAG TTT TTC AAC CTT TTC AGA ACC TGC AAG TCC AAA ATT GAA GAC ATT AAG TCA GAA CAA GAA AAA GAA GCG GAG AAG TGC ATC CGA CTG CAC TTC CAG ATG GAG CAG ATT GTC TAC TGC CAA GAC CAA GCG TAC CGG GCT TCG CTG CAG AAG ATC CGA GAG AAG GAA TCG GAA GAG AAG AAG GGT TGT TCG CGC CAG CAG AAG GAG CAG AAT TTC TAT CAG GAG GAT CCT TTG ACT TGT TCC CTC ACT GAA ATC CTC CAA CAC CTA ATG GCC TAC CGC CTG GAG GCC AGC AAC CGC CTG TCC AGC CAC ATC CCT CTG ATC ATC CAG TTC TTC ATC CTC CAG TCG AAC GGG CAG CAG CTG CAG AAG GCC ATG CTC CAG CTG CTG CAG GAC AAG GAG AAG TAC GAC TGG CTC CTC AAG GAG CGC AAC GAC ACG AGC GAC AAG CGC AAG TTC CTG AAG GAG CGG CTG GCG CGG CTG ACC AAG GCC CGG CGC CGG CTG GCC CAG TTC CCG GGC TAA
--- --- --- --- --- --- --- --- --- --- --- --- ATG GAG ACA GCG ACT CCC GAC TCC GCC TCT GCA TCC AGT CAG CCC TTA CCC AAT GGA GAT GCT GTG GTG CCA GAA GTA AAC ATG GAG ACA ATG CTG GAG ACC AGC CTG TGC AGC CAG TAC GAG GAG AAG GTG CGG CCC TGC ATC GAC CTC ATC GAC TCC CTG CGG GCC CTG GGC GTG GAG CAG GAC CTG GCC CTG CCC GCC ATC GCC GTC ATC GGG GAC CAG AGC TCG GGC AAG AGC TCC GTG CTG GAG GCG CTG TCG GGT GTC GCC CTC CCC AGA GGC AGC GGT ATT GTT ACA AGA TGC CCC CTG GTG CTG AAA CTG AGA AAA --- CTT AGG CAT GAT GAT GAT GAG TGG AAA GGC AAA GTC ACT TAC CGG GAC ATG GAG ATC GAT CTT ACG GCC GCT TCG GAG GTA GAA CAG GAA ATC AGG AAA GCC CAG AAT GTC ATT GCT GGG GAA GGT GTG GGA ATC AGT CAG GAG CTA ATT AAT CTG GAG GTC AGC TCC CCT CAC GTG CCA GAT CTG ACC CTG ATA GAC CTT CCT GGC ATC ACC AGA GTC GCT GTG GGC AAT CAG CCA GCT GAC ATT GGA CGT CAG ATT ACA ACT CTC ATC AAG AAG TAC ATC CTG AGG CAG CAG ACC ATC ATG TTG GTG GTG GTG CCC AGT AAC GTG GAC ATC GCC ACC ACA GAG GCG CTG AGC ATG GCC CAG GAG GTA GAC CCC GAA GGA GAC AGG ACC ATA GGG ATC CTG ACA AAG CCC GAC CTG GTG GAC AGA GGC ACC GAA GAC AGA ATC GTG GAC GTG GTG CGG AAC CTG GTC TAC CAC CTG AAG AAG GGC TAC ATG ATC GTC AAG TGT CGG GGC CAG CAG GAC ATC CAG TAC CAG ATA AGC CTG GCC AAG GCT CTG CAG AGG GAG AGG GCC TTC TTC GAG GAC CAT CCC TAT TTC AGG GAT CTC CTG GAG GAG GGC AAG GCC ACC ATC CCC TGC CTG GCA GAG AGA CTG ACC AAT GAG CTC ATT GCA CAC ATC AGT AAA TCT CTG CCC CTG CTG GAA AGT CAG ATA AAG GAG AAC CAG CAG ACC ATT ACG GAG CAG CTG CAG AAG TAT GGC CTG GAC ATC CCG GAA GAC GAA ACG GAG AAA ATG TTC TTC CTG ATT GAC AGG ATC AAC ACG TTC AAT CAG GAC ATC GAG GCG TTG GTG GAG GGG GAG GAG TCC GTG GGG GGC GAC GAC AGC CGG CTG TTC ACC AGG ATC CGG CTG GAG TTC TGC AAG TGG GGC CTG GAG ATC GAG AAC AAC TTC CAG AGA GGC TAT GAG GAC ATT GTC AGA CAC ATC AAG AAG TTT GAA AAC CAG TAT CGC GGC AAA GAG CTG CCG GGG TTC GTG AAC TAC AAG ACG TTC GAG ATG ATC ATA AAG AAG CAG GTG AAG GCC CTG GAG GAC CCG GCG GTG GAG ATG CTG CAC AGG GTC ACC GAT ATG GTC CGG CTT GCC TTC GCA GAT GCT TGC AAG AAA AAT TAC GAG GAG TTC TTC AAC CTC TTA AGA ACC TGC GTG TCC AAA ATT GAA GAC ATT AAG TCA GAA CAA GAA AAA GAA GCG GAG AAG TCC ATC CGA CTG CAC TTC CAG ATG GAG CAG ATT GTC TAC TGC CAA GAC CAG GCG TAC CGC ACC GCG CTG GGA AAG ATC CGA GGG ATG GAA GCC GAA GAG AAT --- --- --- AAG AAG AAG AAG AAG GAG CAT ATT TTC TTT GAA GAG GAC CCT TTG TCC TGC TCC CTC TCT GAA ATC CTC CAA CAC CTG ATG GCC TAC CGC CTG GAG GCC AGC CGA CGC CTG TCC AGC CAC ATC CCT CTG ATC ATC CAG TTC TTC ATC CTG CAG TCC AAC GGG CAG CAG CTG CAG AAG GCC ATG CTC CAG CTG CTG CAG GAC AAG GAC AAG TAC AGC TGG CTC CTC AAG GAG CGC GGC GAC ACC AGC GAC AAG CGC AGG TTC CTG AAG GAG CGG CTG GCG CGG CTG ACC AAG GCC CGG CGC CGG CTG GCC CAG TTC CCG GGC TAA
--- --- --- --- --- --- --- ATG GTT CAT TCT GAC CTG CAA ACC GAA AAT CCC AGT TCG GCC TCT ACA TCC AAT GAT GAG CTA CCA AAT ACA AAT GCT GAT AGG CCT GAG AAA AAT CTG GCC ACG AAG CTG GAG CAC CAC CTG TGC AGC CAC TAC GAG GAG AAG GTG CGC CCC TGC ATT GAC CTC ATC GAC TCC CTG CGG GCC CTG GGC GTG GAG CAG GAC CTG GCC CTG CCC GCC ATC GCC GTC ATC GGG GAC CAG AGC TCG GGC AAG AGC TCC GTG CTG GAG GCC CTG TCG GGC GTC GCC CTC CCC AGA GGC AGC GGT ATT GTG ACA AGA TGC CCC CTG GTG CTG AAA CTG AAA AAA --- CTT AAG AGT --- GAA GAG AAG TGG ACA GGC AAG ATC AGT TAC AAG GAC ATT GAG ATT AAC CTT TCA TCC CCG TCA GAG GTC GAG AAG GAA ATC AGC AAG TCT CAG AAT ATC ATT GCC GGG GAA GGT GTG GGG ATC AGT CAT GAG CTA ATC AGT CTG GAA GTC AGC TCC CCA CAC GTC CCA GAT CTG ACC CTG ATA GAT CTT CCT GGC ATC ACC AGG GTG GCC GTG GGT GAT CAG CCA GCT GAC ATC GGA TAT CAG ATT AAG GCA CTT ATC AGG AAG TAC ATC CAG AGG CTA GAG ACC ATC AAC CTG GTG GTG GTC CCC TGC AAT GTG GAC ATC GCC ACC ACG GAG GCG CTG AGC ATG GCT CAG GAG GTG GAC CCC GAG GGA GAC AGG ACC ATA GGG ATC CTG ACG AAG CCC GAC CTG GTG GAC AAA GGC ACG GAA GAC AAG ATA GTA GAT GTG GCC CGA AAC CTC ATC TGC CAC CTG AAG AAG GGC TAC ATG ATC GTC AAG TGC CGA GGC CAA CAG GAC ATC CAG GAC AAG ATG AGC CTG ACC GAG GCT CTG TGT AAA GAG AAG ACC TTT TTC GAG GAA CAT CCA CAT TAC AGG GAT CTC CTC AAG GAG GGA AGA GCC ACG GTG CCT TGC CTG GCA GAA CGA CTG ACC ACA GAG CTC ATC GAA CAC ATC TGT AAA TCC CTG CCC CGG CTA GAA AAG CAA ATA AAG GAG AAG CAG CAG AAA ATT ACA GAG GAT TTA CAG AAG TAT GGA GTG GAC ATA CCG GAA GAA GAG AGT GAA AAA GTG ATC TTT CTG ATT GAA AAA ATT AAA GCA TTT AAT GAG GAC ATC CGC ACG CTC ATA GAC GGG GAG GAA TCT GTC GGG GAG TAC GAC ACT CGG ATG TTC AAC AAA GTC CGG AGT GAG TTT TAC AAG TGG AGC CTC GTG GTT CAC TCC ACT TTC AAG GAA GGT CAT ATG AAA CTG CTA AAC AAG ATC TTG GAG TTT GAA AAT CGG CAT CGC GGC AGA GAG CTG CCA GGA TTT GTG AAT TAC AAG ACC TTC GAG AAC CTT GTA CGA GAG CAA CTG AAG ACG CTG GAA GAG CCG GCT TTG GAC ACG CTG CAC GCC GTG ACC AAA ATA GTC CAC CTT GCC TTC TCC GAT GTT ACC AAG AAA AAC TAT GAG GAA TTT TTC AAC CTC TTC AAA GTC TGC AAG GCC AGC GTT GAA GAC ATC AAG GTC AAA CAG GAG GAG GAG GCC GAG AAG TCC ATC CGA CTC CAG TTC CAA ATG GAG CAG ATT GTC TAC TGC CAG GAC CAA GAG TAT CGG ACT CAT CTA CAG ATG ATC AGA GAG AAG GAA TTA GAA GAA AAC --- --- --- --- AAG AAG AAG TCC GTC TTT GCG CTT TCT GAA AAC AAT TCC --- CAA AGC TTC CTC GAT GAA ATC CAC CAG CAC CTG TGG GCC TAC TAC CAG GAG GCC AGC AAA CGC CTG TCC AGC CAG ATC CCT CTG ATC ATC CAG TTC TTC ATG CTC CGG TCG TAC GGC CAG AAG CTG AAC AAC GCC ATG CTG CAG CTG CTG CGG GAC AGG GAG AAC TAC GAC TTG CTC CTC ACC GAG CGC AGT GAC ACC AGC GAC AAG AGG AAG TTC CTG AAG GAG CAG CTT TCA CGG CTG ACG AAG GCT CGG TTA CAG TTA GCC CGG TTC CCC GGT TAA
--- --- --- --- --- --- --- ATG GTT CGT TCT GGC CTG CAA ACC AGA AAT CCC AAT TCT --- TCT ACA TCC AAT CGT GAA CAA TCA AAT GAA AAT GCT GAT GAG CCA AAG AAA AAT CGG GAC ACA --- CTC GAG CAC CAC CTG TGC AGC CAG TAT GAG GAG AAG GTG CGT CCC TGC ATC GAC CTC GTG GAC TCC CTG CGG GCC CTG GGC GTG GAG CAG GAC CTG GCC CTG CCC GCC ATC GCC GTC ATC GGG GAC CAG AGC TCA GGC AAG AGC TCC GTG CTG GAG GCC CTG TCG GGT GTC GCC CTC CCC AGA GGC AGT GGT ATT GTG ACA AGA TGC CCC CTG GTG CTG AAG CTG AAG AAT --- CTT AAG GAT --- GAA GAG AAG TGG ACA GGC AAA ATC AGT TAC AAG GAT ATT GAG ATT AAC CTT TCA GAT CCT TCA GAG GTA GAG AAG GAA ATC AAC AAG TCC CAG AAT GTC ATT GCC GGG GAA GGT GTG GGG ATC AGT CAT GAG CTG ATC AGT CTG GAA GTC AGG TCC CCG CAC GTC CCA GAT CTG ACC CTG ATA GAT CTT CCT GGC ATC ACC AGG GTG GCT ATG GGC AAC CAG CCA GCT GAC ATC GGA CAT CAG ATC AAG AGG CTC ATC AGG AAG TAC ATC CAG AGG CAA GAG ACC ATC AAC CTG GTG GTG GTG CCC TGC AAC GTG GAC ATC GTC ACC ACA GAG GCG CTG AGC ATG GCT CAG GAG GTG GAC CCC GAG GGA GAC AGG ACC ATA GGA ATC CTG ACC AAG CCC GAC CTG GTG GAC AAA GGC GCC GAA GAC AAG ATA GTA GAC GTG GCG CGA AAC CTC GTC TGC CAC CTG AAG AAG GGT TAC ATG ATT GTC AAG TGC CGG GGT CAG CAG GAC ATC CAG GAC AGG ATG AGC CTG GCC CAG GCT CTG TGC AAC GAG AAG GCC TTC TTC CAG GAA CAC CCG CAG TAC AGG GAT CTC CTC ACG GAG GGA AGA GCC ACG GTG CCC TGC CTG GCG GAA CGA CTG ACC ATG GAG CTC ACC GAA CAC ATC AGT AAA TCT CTG CCC CAG TTA GAA AAG CAA ATA AAG GAG AAA CAG CAG AAA GTC ACG GAG GAC TTA CAG AAG TGT GGA ATG GAC ATA CCG GAA GAG GAA AGT GAA AAA GTG ATC TTC CTG ATT GAA AAA ATT CAA GCA TTT AAT GAG GAC ATC CGC ACT TTA ATA GAC GGG GAG GAA TTC GTG GAG GAG GAC GAC ACT CGG ATG TTC AAC AAA GTC CGG AGT GAG TTT TAC AAT TGG AGC CTC ATA GTT CAT TCC AGT TTC AAA AAG GGT TAT GAG AAA ATT GTA AAC AAG ATC ATA GAG TTT GAA AAT CGG CAT CGT GGC AGA GAG CTG CCA GGC TTT GTG AAT TAC AAG ACA TTT GAG AAC CTC GTA AGA CAG CAG CTG AAA ACC CTG GAA GAG CCA GCT TTG GAC ATG TTG CAC ACC GTA ACC AAA ATA GTC CAC CTT GCC TTC TCA AAT GTT ACC AAG AAA AAT TAT GAA GAA TTT TTC AAT CTC CTC AAA GTC TGC AAG GCC AGC GTC GAA GAC ATT AAG GTA AAA GAA GAG GAG GAG GCC GAG AAG TGC ATC CGA CTC CAG TTC CAA ATG GAG CAG ATT GTC TAC TGC CAA GAC CAA GAA TAT CGG ACT TGG CTG CAG AAG ATC AGA GAG AAG GAA TTA GAA CAA CAG --- --- --- --- AAA AAG AAA CTG GCC TTT GCG CCT TCT GAA AAC AGC TCT TCC CAG AGC TTC CTC GAC GAA ATC CAC CAA CAC CTG TGG GCC TAC CAC CAG GAG GCC AGC AAA CGC CTG TCC AGC CAA ATC CCG CTG ATC ATC CAG TTC TTC ATG CTC CGG TCC TAC GGC CAG AAG CTG AGC AGC GCC ATG TTG CAG CTG CTG CAG GAC AGG GAG AGC TAC AAC TCG CTC CTC GCA GAG CGC AGT GAC ACC AGC GAC AAG AGG AAG TTC CTC AAG GAG CAG CTT GCG CGG CTG ACA AAG GCT CGG CGC CAG TTG TCC AAA TTC CCC GGT TAA
--- --- --- --- --- --- --- ATG GTT CGT TCT GGC CTG CAA ACG GAA AAT CCC AAT TCG GCT TCT GTA TCC AAT CAT GAA CAA TCA AAT GAA AAT GCT GAT AAG CCA AAG AAA AAT GTG GAC ACA GAG CTC GAG CAC CGC CTG TGC AGC CAG TAC GAG GAG AAG GTG CGC CCC TGC ATC GAC CTC GTG GAC TCC CTG CGG GCC CTG GGC GTG GAG CAG GAC CTG GCC CTG CCC GCC ATC GCC GTC ATC GGG GAC CAG AGC TCG GGC AAG AGC TCC GTG CTG GAG GCC CTG TCG GGC GTC GCC CTC CCC AGA GGC AGC GGA ATC GTA ACC AGG TGT CCA CTG GTG CTA AAG CTG AAA AAG CAG CTC TCG AGG --- GAT GTG TCT TGG AGG GGG AAG ATC AGC TAC CAG AAC ACG GAG CTC CCG CTT CAG GAC CCC TCC CAG GTG GAG AGG GAA ATC AAC AAA GCC CAA AAC ATC GTG GCT GGG AGT GGA GTT GGC ATC AGC CAC GAG CTC ATC AGT CTG GAG ATC TCC TCC CCT GAC GTC CCG GAC CTG ACC CTT ATT GAT CTT CCC GGC ATC ACC AGG GTG CCT GTG GGA AAT CAG CCC GTG GAC ATC GGA CAT CAG ATC AAG GCG CTC ATC AGG AAG TAC ATC CAG AGG CAG GAG ACC ATC AAC CTG GTG GTG GTG CCC TGC AAC GTG GAC ATC GCC ACC ACA GAG GCG CTG AGC ATG GCT CAG GAG GTG GAC CCC GAG GGA GAC AGG ACC ATC GGA ATC CTG ACC AAG CCT GAC CTG GTG GAC AAA GGC ACC GAA GAC AAG ATA GTA GAC GTG GTG CGA AAC CTC GTC TGC CAC CTG AAG AAG GGC TAC ATG ATT GTC AAG TGC CGG GGT CAG CAG GAC ATC CAG GAT AGA ATG AGC CTG GCC CAG GCT CTG AGT AAA GAG AAG GCC TTC TTC CAG GAA CAC CCG CAG TAC AGG GTT CTC CTC GCA GAG GGA AGA GCC ACG GTG CCC TGC CTG GCG GAA CGG CTG ACC ACG GAG CTC ACC GAA CAC ATC AGT AAA TCT CTG CCC CGG TTA GAA AAG CAG ATA AAG GAG AAA CAG CAG AGT GTC ATA GCG GAT TTA GAG ATG TGT GGA ATG GAC ATA CCG GAA GAG GAA GGC GAG AAA GTG ATC TTT TTG ATT GAA AAA ATT AAA GCA TTT AAT GAG GAC ATC CGC ACT TTA ATA GAT GGG GAG GAA TTT GTG GAG GAG AAT GAC ACT CGG ATG TTC AAC AAA GTC CGG AGT GAG TTT TGC AAA TGG AGC ATC ATG GTT CAT TCC AGC TTC GAA AAG GGT TAC AAG AAA ATT GTA AAC AAG ATC ATG GAG TTT GAA AAT CGG CAT CGC GGC AGA GAG CTG CCG GGA TTT GTG AAT TAC AAG ACG TTC GAG AAC CTT GTG AGA CAG CAG CTG AAA ACA CTG GAA GAG CCA GCT TTG GAC ATG CTG CAC ACC GTC ACC AAA ATA GTC CAC CTT GCC TTC TCA GAT GTT ACC AAA AAA AAT TAT GAG GAA TTT TTC AAT CTC CTC AAA GTC TGC AAG GCC AGC GTG GAA GAC ATT AAG CTG AAA CAA GAA GAG AAG GCC GAG GAG TCC ATC CGC CTC CAG TTC CAA ATG GAG CAG GTT GTG TAC TGC CAA GAC CAA GAG TAT CGG ACT TGG CTG CAG AAG ATC CGA GAG AAG GAA TCA GAA CAA CAG --- --- --- --- AAA AGG AAA TCC ACC TTG GTG ACT TCT GAA AGC AGC TCT TCC CAA AGC TTC CTT GAC GAG ATC CAC CAA CAC CTG TGG GCC TAC CAC CAG GAG GCC AGC AAA CGC CTG TCC AGC CAA ATC CCG CTG ATC ATC CAG TTC TTC ATG CTC CGG TCG TAC AGC CAG AAG CTG AGC AAT GCC ATG TTG CAG CTG CTG CAG GAC AAG GAG AAG TAC GGC TGG CTC CTC ACA GAG CGC AAT GAC ACC AGC GAC AAG AGG AAG TTC CTG AAG GAG CAG CTT GCA CGG CTG ACA AAG GCT CGG CTC CAG TTA TCC AAA TTC CCC GGT TAA
F3X4, M1a vs M2a | LRT is significant
lnL_M1a = -9734.09
lnL_M2a = -9693.18
LRT: χ2 = 81.82
% sites with ω > 1 = 4.74
avg(ω) = 4.23
p < 0.001
0.701 0.844 0.571 0.959 0.931 0.947 0.862 0.905 0.959 0.884 0.915 0.602 0.834 0.878 0.937 1.000 0.984 0.929 0.968 0.992 0.924 0.991
F3X4, M7/M8a vs M8 | LRT is significant
lnL_M7 = -9738.25 / lnL_M8a = -9727.16
lnL_M8 = -9687.55
LRT: χ2 = 101.39 / LRT: χ2 = 79.21
% sites with ω > 1 = 6.26
avg(ω) = 3.45
p < 0.001 / p < 0.001
0.874 0.932 0.594 0.590 0.763 0.642 0.783 0.981 0.971 0.982 0.725 0.705 0.948 0.961 0.985 0.953 0.967 0.843 0.931 0.953 0.521 0.965 1.000 0.746 0.992 0.969 0.985 0.996 0.512 0.600 0.972 0.728 0.995 0.635
F1X4, M1a vs M2a | LRT is significant
lnL_M1a = -9805.43
lnL_M2a = -9776.37
LRT: χ2 = 58.12
% sites with ω > 1 = 4.66
avg(ω) = 3.45
p < 0.001
0.654 0.535 0.871 0.768 0.743 0.907 0.867 0.953 0.706 0.631 0.879 0.758 1.000 0.700 0.991 0.945 0.965 0.963 0.518 0.914 0.976
F1X4, M7/M8a vs M8 | LRT is significant
lnL_M7 = -9810.71 / lnL_M8a = -9801.87
lnL_M8 = -9772.54
LRT: χ2 = 76.34 / LRT: χ2 = 58.65
% sites with ω > 1 = 7.05
avg(ω) = 2.79
p < 0.001 / p < 0.001
0.660 0.730 0.524 0.765 0.891 0.843 0.954 0.921 0.598 0.929 0.587 0.567 0.692 0.778 0.971 0.955 0.986 0.714 0.902 0.774 0.859 0.963 0.594 0.897 1.000 0.900 0.995 0.977 0.985 0.986 0.542 0.842 0.972 0.990 0.594
F61, M1a vs M2a | LRT is significant
lnL_M1a = -9832.25
lnL_M2a = -9800.79
LRT: χ2 = 62.91
% sites with ω > 1 = 5.7
avg(ω) = 3.26
p < 0.001
0.615 0.696 0.784 0.820 0.827 0.893 0.845 0.695 0.784 0.955 0.880 0.977 0.608 0.720 0.650 0.765 0.962 0.577 0.890 1.000 0.799 0.987 0.959 0.944 0.937 0.522 0.847 0.926 0.982
F61, M7/M8a vs M8 | LRT is significant
lnL_M7 = -9840.32 / lnL_M8a = -9830.88
lnL_M8 = -9798.89
LRT: χ2 = 82.85 / LRT: χ2 = 63.98
% sites with ω > 1 = 8.06
avg(ω) = 2.75
p < 0.001 / p < 0.001
0.915 0.550 0.699 0.616 0.685 0.660 0.867 0.933 0.816 0.559 0.744 0.838 0.704 0.962 0.970 0.649 0.693 0.968 0.979 0.536 0.810 0.865 0.976 0.861 0.646 0.945 0.854 0.625 0.670 0.846 0.962 0.992 0.553 0.978 0.996 0.651 0.916 0.567 0.947 0.922 0.952 0.993 0.905 0.858 0.975 1.000 0.962 0.997 0.991 0.989 0.989 0.875 0.976 0.987 0.996 0.804 0.630 0.618 0.605 0.512 0.633 0.533 0.555 0.630
M N P P T V K R S P L K V K V K N H N S A S A S S P R L P D A K V - - S E E N L E K G T E S S L C S Y Y E E K I R P C I D L I D S L R A L G V E Q D L A L P A I A V I G D Q S S G K S S V L E A L S G V A L P R G S G I V T R C P L V L K L R K - L R D - G D E W K G K V S Y K D Q E I E M S D A S E V E E E I R K A Q D V I A G V G M D I S H E L I N L E V S S P H V P D L T L I D L P G I T R V A L G N Q P A D I G F Q I K R L I K K Y I L K Q Q T I N L V V V P S N V D I A T T E A L S M A Q E V D P D G D R T I G I L T K P D L V D K G T E N K V V D V V R N L V C H L K K G Y M I V K C R G Q Q D I Q E Q L S L T E A L Q K E K A F F E D H P H F R N L L D E G K A T I P C L A E R L T T E L I A H I C K S L P Q L E N E I K E K Q Q S I T E E L Q M Y G M E T P E E E N E K M F F L I D K L N A F N Q G I L T L I Q G E E I V E K S N T R L F T K I R K E F N N W S K V I E N N F Q D G Y D A V Y N E I C K F E N Q Y R G R E L P G F V N Y K T F E N I I K Q Q I K T L E E P A V D M L H T V T Q M V W L A F T E V S Q K N Y S E F F N L Y K V S K S K I E D I K T E Q E R E A E K S I R L H F Q M E Q I V Y C Q D T M Y Q R S L R K I R E K E K E K E - E E R K R T L G R A I C E E S S S Y N S L D E I F Q H L I A Y H Q E T G N R L S T H I P L T I Q F F V L Q S F G Q Q L Q K A M L Q L L Q D K E Q Y D W L L K E R S D T C D K R K F L K E Q H R R L V Q A R H Q L A K F P G X
- - - - - - - M G V P Q G K I Q N H D L A F A A S P P L P N T E V - - S E K N P E K R E E S S L C S H Y E E K V R P C I D L I D S L R A L G V E Q D L A L P A I A V I G D Q S S G K S S V L E A L S G V A L P R G S G I V T R C P L V L K L R K - V R D - G D E W K G K V S Y H D V E V E I S D P L E V E K E I S K A Q D A I A G V G M D I S H E L I D L E V S S P H V P D L T L I D L P G I T R V A V G N Q P A D I G Q Q I K K L I R K Y I L K Q E T I N L V V V P S N V D I A T T E A L S M A Q E V D P D G D R T I G I L T K P D L V D K G T E N R V V D V V Q N L V C H L K K G Y M I V K C R G Q Q D I Q D Q L S L A E A L Q K E K A F F E D H S H F R V L L E E G K A T I P C L A E R L T A E L I T H I C K S L P W L E N E I K E K Q Q K I T E E L Q K Y G T E I P E D E N E K T F F L M D K I N A F N Q A I L A L V Q G E E I V E N N D I R L F T K I R N E F N K W S K V I E K N F Q E G Y S A I H N E I W K F E N Q Y R G R E L P G F V N Y K T F E S I I R Q Q I K T L E E P A V D M L H T V A D K V W L A F A E V A Q K N Y N E F F N L H K V S K S K I E D I K T E Q Q K E A E K S I R L H F Q M E Q I V Y C Q D Q M Y Q S S L Q K I R A K E K E K E - - E E M K K K F N C L N L Q Q S S S N S L D E I F Q H L T A Y H Q E T S K R L S T H I P L V I Q F F I L R S F G Q K L Q M A M L Q L L Q D K E Q Y D W L L K E R S D T C D K R K F L K E Q H K R L V E A R H E L A K F T C X
- - - - - - - M G V P Q V K V Q G H S S D L A S A P Q L P N A E V - - P E K N L K K G E E T D L C S H Y E E K V R P C I D L V D S L R A L G V E Q D L A L P A I A V I G D Q S S G K S S V L E A L S G V A L P R G S G I V T R C P L V L K L R Q - A R D - G G A W K G K V S Y Q D E E V E I P D P S A V E R E I R K A Q D A M A G V G V G I S H E L I T L E V S S P H A P D L T L I D L P G I T R V A V G N Q P A D I G W Q I K A L I R K Y I Q K Q E T I N L V V V P S N V D I A T T E A L S M A Q E V D P D G D R T I G I L T K P D L V D K G T E H R V V D V V R N L V C P L K K G Y M I V K C R G Q Q D V Q G Q L S L A E A L R K E K A F F A D H P S Y R D L L E E G M A T I P C L A E R L T A E L I A H I C K S L P W L E N E I K E K Q Q N I T E E L Q K Y G T E I P E D E S E K M F F L I D K I N A F N Q G I L A L T Q A E E L V G K N D T R L F T K I R N E F N S W S K M I D R S F Q A G Y S A L E S E I L K F E N Q Y R G R E L P G F V N Y K T F E S I V K Q Q M K T L E E P A V E M L H T V T E M V W R A F A D V S Q K H F N E F F N L Y R V S K S K I E D L K T E K E R E A E K F I R I H F E M E Q M V Y C Q D Q V Y Q R S L Q K V R E K E N E E Q - - N K N K S R V L D L V Q S S P D S S P L G E I L P H L T A Y R Q D A R D R L A T H I P L V I Q F F V L Q S F G Q Q L Q K S M L Q L L Q D K E Q Y G W L L R E R S D T C E K R K R L K E Q H R R L V Q A R H R L A Q F P G X
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