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• Activity deltas table
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Motif ID: ATF5_CREB3.p2

Z-value: 1.998

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_+_45971249	10.103	NM_001114171 NM_006732	FOSB	FBJ murine osteosarcoma viral oncogene homolog B
chr12_+_52445185	7.873	NM_002135 NM_173157	NR4A1	nuclear receptor subfamily 4, group A, member 1
chr14_+_75745480	7.124	NM_005252	FOS	FBJ murine osteosarcoma viral oncogene homolog
chr11_-_1593149	6.269	NM_004420	DUSP8	dual specificity phosphatase 8
chr19_+_49375679	6.061		PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr19_+_49375677	6.061		PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr4_+_75480628	5.961	NM_001657	AREG	amphiregulin
chr9_+_102584136	5.943	NM_006981 NM_173199 NM_173200	NR4A3	nuclear receptor subfamily 4, group A, member 3
chr19_+_49375638	5.896	NM_014330	PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr7_+_28448970	4.500		LOC401317	uncharacterized LOC401317
chr8_-_95274540	4.461	NM_005261 NM_181702	GEM	GTP binding protein overexpressed in skeletal muscle
chr6_+_89791510	4.363		PNRC1	proline-rich nuclear receptor coactivator 1
chr5_-_172198160	4.317	NM_004417	DUSP1	dual specificity phosphatase 1
chr6_-_91006580	4.312	NM_001170794	BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr5_+_137801178	4.277	NM_001964	EGR1	early growth response 1
chr2_+_28615771	4.258	NM_005253	FOSL2	FOS-like antigen 2
chr22_+_38597938	4.237	NM_001161572 NM_001161574 NM_012323	MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr6_-_91006460	4.111	NM_021813	BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr2_+_28615695	4.110		FOSL2	FOS-like antigen 2
chr8_-_95274520	3.970		GEM	GTP binding protein overexpressed in skeletal muscle
chr5_+_137801166	3.787		EGR1	early growth response 1
chr7_-_100808832	3.679	NM_003378	VGF	VGF nerve growth factor inducible
chr22_+_38598065	3.628		MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr12_-_123380608	3.568
chr1_+_212781969	3.432	NM_001040619 NM_001206484 NM_001206488 NM_001674	ATF3	activating transcription factor 3
chr1_+_212782103	3.356		ATF3	activating transcription factor 3
chr2_+_28615668	3.344		FOSL2	FOS-like antigen 2
chr10_+_104154228	3.241	NM_001077493 NM_001077494	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr21_-_43430448	2.920	NM_001098402 NM_001098403 NM_020727	ZNF295	zinc finger protein 295
chr16_-_66959418	2.887	NM_001128850 NM_004165	RRAD	Ras-related associated with diabetes
chr8_+_128806720	2.779		PVT1	Pvt1 oncogene (non-protein coding)
chr4_-_89618928	2.662	NM_153757	NAP1L5	nucleosome assembly protein 1-like 5
chr12_-_123380682	2.599	NM_024667	VPS37B	vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr3_-_8543327	2.490		LOC100288428	uncharacterized LOC100288428
chr20_-_44600939	2.483		ZNF335	zinc finger protein 335
chr3_-_42814734	2.442	NM_144719	CCDC13	coiled-coil domain containing 13
chr19_-_18392048	2.409		JUND	jun D proto-oncogene
chr12_-_123380628	2.397		VPS37B	vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr7_+_1577118	2.387		MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr1_+_86046434	2.378	NM_001554	CYR61	cysteine-rich, angiogenic inducer, 61
chr11_-_65667809	2.372		FOSL1	FOS-like antigen 1
chr17_-_40828078	2.345		PLEKHH3	pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr2_+_220408352	2.289		TMEM198	transmembrane protein 198
chr3_+_50297644	2.259
chr19_+_45504686	2.241	NM_006509	RELB	v-rel reticuloendotheliosis viral oncogene homolog B
chr14_-_23388294	2.231		RBM23	RNA binding motif protein 23
chr11_+_73087396	2.218	NM_152222	RELT	RELT tumor necrosis factor receptor
chr19_-_18392413	2.214	NM_005354	JUND	jun D proto-oncogene
chr10_-_31320772	2.178	NM_001143766 NM_001143767 NM_001143768 NM_001143770 NM_001143771 NM_182755	ZNF438	zinc finger protein 438
chr2_+_220408742	2.162	NM_001005209	TMEM198	transmembrane protein 198
chr2_-_145277568	2.135		ZEB2	zinc finger E-box binding homeobox 2
chr13_-_21635629	2.133		LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)
chr2_-_157189040	2.129	NM_006186	NR4A2	nuclear receptor subfamily 4, group A, member 2
chr2_-_172967627	2.120		DLX2	distal-less homeobox 2
chr14_-_23388380	2.112	NM_001077351 NM_001077352 NM_018107	RBM23	RNA binding motif protein 23
chr19_+_35491225	2.081	NM_001136199 NM_020895	GRAMD1A	GRAM domain containing 1A
chr13_-_21635703	2.060	NM_014572	LATS2	LATS, large tumor suppressor, homolog 2 (Drosophila)
chr19_-_47734215	2.053	NM_014417	BBC3	BCL2 binding component 3
chr15_+_93447702	2.038		CHD2	chromodomain helicase DNA binding protein 2
chr5_-_57755787	2.027	NM_001252226 NM_006622	PLK2	polo-like kinase 2
chr19_+_12902295	2.005	NM_002229	JUNB	jun B proto-oncogene
chr1_+_37940074	1.991	NM_025079	ZC3H12A	zinc finger CCCH-type containing 12A
chr20_-_44600787	1.972	NM_022095	ZNF335	zinc finger protein 335
chr11_-_65667860	1.958	NM_005438	FOSL1	FOS-like antigen 1
chr12_-_132628841	1.952	NM_175066	DDX51	DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr1_-_193155723	1.926	NM_003783	B3GALT2	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr5_-_37839781	1.909	NM_000514	GDNF	glial cell derived neurotrophic factor
chr2_-_201729351	1.869		CLK1	CDC-like kinase 1
chr11_+_66610882	1.862	NM_001032279 NM_005133	RCE1	RCE1 homolog, prenyl protein protease (S. cerevisiae)
chr20_-_62258422	1.860		GMEB2	glucocorticoid modulatory element binding protein 2
chr6_+_135818938	1.857		LINC00271	long intergenic non-protein coding RNA 271
chr1_-_19536741	1.840	NM_020765	UBR4	ubiquitin protein ligase E3 component n-recognin 4
chr2_-_201729241	1.836	NM_001162407	CLK1	CDC-like kinase 1
chr3_-_53925871	1.812	NM_021237	SELK	selenoprotein K
chr1_-_16482426	1.809	NM_004431	EPHA2	EPH receptor A2
chr19_-_18392436	1.806		JUND	jun D proto-oncogene
chr11_+_111749947	1.793	NM_022761	C11orf1	chromosome 11 open reading frame 1
chr1_+_45266035	1.791	NM_004073	PLK3	polo-like kinase 3
chr2_-_145277879	1.787	NM_001171653 NM_014795	ZEB2	zinc finger E-box binding homeobox 2
chr8_-_144623579	1.782		ZC3H3	zinc finger CCCH-type containing 3
chr10_+_104155431	1.743	NM_002502	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr7_+_1580009	1.718		MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr17_-_72968790	1.713	NM_030630	C17orf28	chromosome 17 open reading frame 28
chr5_+_78531848	1.706	NM_152405	JMY	junction mediating and regulatory protein, p53 cofactor
chr1_-_713985	1.704		LOC100288069	general transcription factor IIi pseudogene
chr10_+_134210691	1.697	NM_001098637 NM_138499	PWWP2B	PWWP domain containing 2B
chr7_-_140624280	1.695	NM_004333	BRAF	v-raf murine sarcoma viral oncogene homolog B1
chr6_+_139456240	1.667	NM_016217	HECA	headcase homolog (Drosophila)
chr2_+_220144024	1.653	NM_001039550 NM_006736	DNAJB2	DnaJ (Hsp40) homolog, subfamily B, member 2
chr10_-_77161424	1.646	NM_032772	ZNF503	zinc finger protein 503
chr3_+_141087298	1.645		ZBTB38	zinc finger and BTB domain containing 38
chr1_+_45266048	1.624		PLK3	polo-like kinase 3
chr20_-_62258330	1.603	NM_012384	GMEB2	glucocorticoid modulatory element binding protein 2
chr9_-_86432546	1.600	NM_001135953 NM_025211	GKAP1	G kinase anchoring protein 1
chr1_-_59249687	1.600	NM_002228	JUN	jun proto-oncogene
chr19_+_12902286	1.581
chr3_-_39195101	1.567	NM_033027	CSRNP1	cysteine-serine-rich nuclear protein 1
chr2_+_30369749	1.565	NM_001127399 NM_001127400 NM_001127401 NM_016061	YPEL5	yippee-like 5 (Drosophila)
chr2_-_201729377	1.560	NM_004071	CLK1	CDC-like kinase 1
chr17_-_72968750	1.552
chr17_+_27071008	1.534	NM_004295	TRAF4	TNF receptor-associated factor 4
chr11_+_73087670	1.529	NM_032871	RELT	RELT tumor necrosis factor receptor
chr5_-_64777703	1.514	NM_197941	ADAMTS6	ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr17_+_42385780	1.510	NM_001144825 NM_001144826 NM_006695	RUNDC3A	RUN domain containing 3A
chr3_+_183353355	1.509	NM_017644	KLHL24	kelch-like 24 (Drosophila)
chr10_-_77161539	1.507		ZNF503	zinc finger protein 503
chr2_+_43864405	1.496		PLEKHH2	pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr3_-_39195034	1.481		CSRNP1	cysteine-serine-rich nuclear protein 1
chr5_+_78532338	1.471
chr3_+_156544075	1.468	NM_001004316 NM_001193283	LEKR1	leucine, glutamate and lysine rich 1
chr7_-_45128492	1.454	NM_001146334	NACAD	NAC alpha domain containing
chr6_+_138188352	1.452	NM_006290	TNFAIP3	tumor necrosis factor, alpha-induced protein 3
chr5_-_132299248	1.434		AFF4	AF4/FMR2 family, member 4
chr8_+_118532970	1.434		MED30	mediator complex subunit 30
chr2_+_43864433	1.427	NM_172069	PLEKHH2	pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr9_+_35538890	1.425		RUSC2	RUN and SH3 domain containing 2
chr7_+_128312345	1.399	NM_001012454 NM_001128926	FAM71F2	family with sequence similarity 71, member F2
chr16_+_30773619	1.399		RNF40	ring finger protein 40
chr22_-_50683372	1.391	NM_020461	TUBGCP6	tubulin, gamma complex associated protein 6
chr9_-_110252045	1.385	NM_004235	KLF4	Kruppel-like factor 4 (gut)
chr3_-_49823626	1.365	NM_001242829	IP6K1	inositol hexakisphosphate kinase 1
chr10_+_99079017	1.359	NM_005479	FRAT1	frequently rearranged in advanced T-cell lymphomas
chr9_+_35538628	1.356	NM_001135999	RUSC2	RUN and SH3 domain containing 2
chr9_-_110251754	1.354		KLF4	Kruppel-like factor 4 (gut)
chr5_-_132299263	1.344	NM_014423	AFF4	AF4/FMR2 family, member 4
chr19_+_34972866	1.330	NM_001080436	WTIP	Wilms tumor 1 interacting protein
chr20_+_51589752	1.320		TSHZ2	teashirt zinc finger homeobox 2
chr11_-_67141008	1.317	NM_013246	CLCF1	cardiotrophin-like cytokine factor 1
chr19_+_35491329	1.316		GRAMD1A	GRAM domain containing 1A
chr4_-_175204617	1.315		FBXO8	F-box protein 8
chr19_-_42721802	1.311	NM_133328	DEDD2	death effector domain containing 2
chr3_-_49823953	1.303		IP6K1	inositol hexakisphosphate kinase 1
chr11_-_66610703	1.280
chr3_+_150125983	1.264		TSC22D2	TSC22 domain family, member 2
chr1_+_45265896	1.261		PLK3	polo-like kinase 3
chr8_-_11324184	1.259	NM_053279	FAM167A	family with sequence similarity 167, member A
chr2_+_10184371	1.257	NM_001177718	KLF11	Kruppel-like factor 11
chr4_+_668250	1.256		MYL5	myosin, light chain 5, regulatory
chr4_-_926081	1.256		GAK	cyclin G associated kinase
chr1_-_32110464	1.245		PEF1	penta-EF-hand domain containing 1
chr3_-_49823972	1.239	NM_001006115 NM_153273	IP6K1	inositol hexakisphosphate kinase 1
chr6_+_30295007	1.237	NM_172016	TRIM39	tripartite motif containing 39
chr4_-_926101	1.219		GAK	cyclin G associated kinase
chr19_-_3971032	1.203		DAPK3	death-associated protein kinase 3
chr13_+_73633097	1.203	NM_001730	KLF5	Kruppel-like factor 5 (intestinal)
chr16_+_54965110	1.202	NM_001252197 NM_005853	IRX5	iroquois homeobox 5
chr11_-_3818706	1.192		NUP98	nucleoporin 98kDa
chr5_-_132299191	1.192		AFF4	AF4/FMR2 family, member 4
chr2_+_33172368	1.173	NM_206943	LTBP1	latent transforming growth factor beta binding protein 1
chr19_-_3971089	1.170		DAPK3	death-associated protein kinase 3
chr18_+_23806385	1.167	NM_005640	TAF4B	TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chrX_+_49126299	1.165	NM_001184745 NM_033215	PPP1R3F	protein phosphatase 1, regulatory subunit 3F
chrX_+_49126326	1.158		PPP1R3F	protein phosphatase 1, regulatory subunit 3F
chr2_+_30369800	1.158		YPEL5	yippee-like 5 (Drosophila)
chr1_+_157963310	1.153		KIRREL	kin of IRRE like (Drosophila)
chr17_-_17399494	1.149	NM_001199989 NM_016084	RASD1	RAS, dexamethasone-induced 1
chr19_+_55987698	1.147	NM_033113	ZNF628	zinc finger protein 628
chr8_-_29207795	1.146	NM_001394	DUSP4	dual specificity phosphatase 4
chr15_+_90544608	1.142	NM_198526	ZNF710	zinc finger protein 710
chrX_+_49126480	1.139		PPP1R3F	protein phosphatase 1, regulatory subunit 3F
chr15_+_78556485	1.134	NM_018602	DNAJA4	DnaJ (Hsp40) homolog, subfamily A, member 4
chr1_-_214724974	1.121	NM_005401	PTPN14	protein tyrosine phosphatase, non-receptor type 14
chr11_-_65667858	1.120		FOSL1	FOS-like antigen 1
chr16_+_18995508	1.118	NM_001160364	TMC7	transmembrane channel-like 7
chr22_+_42229105	1.117	NM_004599	SREBF2	sterol regulatory element binding transcription factor 2
chr16_+_18995255	1.111	NM_024847	TMC7	transmembrane channel-like 7
chr17_-_8151373	1.110	NM_025099	CTC1	CTS telomere maintenance complex component 1
chr4_-_54930466	1.108		CHIC2	cysteine-rich hydrophobic domain 2
chr3_+_42977833	1.103	NM_001205272	KRBOX1	KRAB box domain containing 1
chr17_-_8151353	1.103		CTC1	CTS telomere maintenance complex component 1
chr11_+_64692052	1.102	NM_006244	PPP2R5B	protein phosphatase 2, regulatory subunit B', beta
chr17_-_76836852	1.101	NM_025090	USP36	ubiquitin specific peptidase 36
chr2_+_220071493	1.099	NM_138802	ZFAND2B	zinc finger, AN1-type domain 2B
chr4_-_69215699	1.096	NM_001031732 NM_133370	YTHDC1	YTH domain containing 1
chr22_-_50682915	1.090		TUBGCP6	tubulin, gamma complex associated protein 6
chr17_-_76836718	1.089		USP36	ubiquitin specific peptidase 36
chr11_+_66059364	1.087	NM_153266	TMEM151A	transmembrane protein 151A
chr3_+_50306305	1.075		SEMA3B	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr4_-_2010702	1.074		WHSC2	Wolf-Hirschhorn syndrome candidate 2
chr13_+_45915479	1.069		LOC100190939	uncharacterized LOC100190939
chr16_-_54320367	1.065	NM_024336	IRX3	iroquois homeobox 3
chr2_+_70142236	1.063		MXD1	MAX dimerization protein 1
chr7_+_123295860	1.059	NM_207163	LMOD2	leiomodin 2 (cardiac)
chr11_-_116968986	1.054	NM_025164	SIK3	SIK family kinase 3
chr21_-_44846927	1.052	NM_173354	SIK1	salt-inducible kinase 1
chr4_-_926114	1.049		GAK	cyclin G associated kinase
chrX_-_52987610	1.047	NM_001242491	FAM156A FAM156B	family with sequence similarity 156, member A family with sequence similarity 156, member B
chr15_+_83478329	1.046		WHAMM	WAS protein homolog associated with actin, golgi membranes and microtubules
chr16_-_67450149	1.043	NM_013304	ZDHHC1	zinc finger, DHHC-type containing 1
chr6_-_70506472	1.037		LMBRD1	LMBR1 domain containing 1
chr15_-_40401041	1.034	NM_001003940	BMF	Bcl2 modifying factor
chr6_+_43445255	1.032	NM_001146016 NM_001146018 NM_001146019 NM_001146020 NM_080604	TJAP1	tight junction associated protein 1 (peripheral)
chr2_-_157186681	1.025		NR4A2	nuclear receptor subfamily 4, group A, member 2
chr6_+_43445304	1.020		TJAP1	tight junction associated protein 1 (peripheral)
chr19_+_39390570	1.013		NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr5_-_175964824	1.010		RNF44	ring finger protein 44
chr4_+_103422553	1.007		NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr1_-_214724844	1.007		PTPN14	protein tyrosine phosphatase, non-receptor type 14
chr2_+_169659099	1.006	NM_001039724 NM_001171632 NM_052946	NOSTRIN	nitric oxide synthase trafficker
chr14_+_105331581	0.998	NM_001112726 NM_015005	KIAA0284	KIAA0284

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
2.18	3.43e-06	GO:0060255	regulation of macromolecule metabolic process
2.55	3.83e-06	GO:0051252	regulation of RNA metabolic process
2.59	4.31e-06	GO:0006355	regulation of transcription, DNA-dependent
3.84	7.00e-06	GO:0006351	transcription, DNA-dependent
2.11	7.34e-06	GO:0080090	regulation of primary metabolic process
2.45	7.98e-06	GO:2000112	regulation of cellular macromolecule biosynthetic process
2.08	1.19e-05	GO:0031323	regulation of cellular metabolic process
2.32	1.55e-05	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.32	1.55e-05	GO:0031326	regulation of cellular biosynthetic process
2.00	1.66e-05	GO:0019222	regulation of metabolic process
2.38	1.73e-05	GO:0010556	regulation of macromolecule biosynthetic process
2.30	2.17e-05	GO:0009889	regulation of biosynthetic process
2.25	3.80e-05	GO:0051171	regulation of nitrogen compound metabolic process
2.31	4.07e-05	GO:0010468	regulation of gene expression
3.46	4.97e-05	GO:0032774	RNA biosynthetic process
16.34	1.33e-04	GO:0051591	response to cAMP
2.14	5.58e-04	GO:0048518	positive regulation of biological process
2.45	7.53e-04	GO:0010467	gene expression
3.16	8.72e-04	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.69	1.80e-03	GO:0043170	macromolecule metabolic process
2.45	1.81e-03	GO:0016070	RNA metabolic process
1.75	2.17e-03	GO:0044260	cellular macromolecule metabolic process
4.10	4.93e-03	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
2.08	6.11e-03	GO:0048522	positive regulation of cellular process
12.01	6.39e-03	GO:0034138	toll-like receptor 3 signaling pathway
5.05	7.24e-03	GO:0006366	transcription from RNA polymerase II promoter
11.64	7.67e-03	GO:0002756	MyD88-independent toll-like receptor signaling pathway
10.97	1.08e-02	GO:0034130	toll-like receptor 1 signaling pathway
10.97	1.08e-02	GO:0034134	toll-like receptor 2 signaling pathway
2.11	1.22e-02	GO:0090304	nucleic acid metabolic process
10.37	1.50e-02	GO:0002755	MyD88-dependent toll-like receptor signaling pathway
14.33	1.52e-02	GO:0001704	formation of primary germ layer
3.14	1.69e-02	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
9.96	1.89e-02	GO:0008063	Toll signaling pathway
9.96	1.89e-02	GO:0034142	toll-like receptor 4 signaling pathway
2.29	2.11e-02	GO:0034645	cellular macromolecule biosynthetic process
3.05	2.47e-02	GO:0051173	positive regulation of nitrogen compound metabolic process
2.26	2.61e-02	GO:0009059	macromolecule biosynthetic process
8.90	3.57e-02	GO:0002224	toll-like receptor signaling pathway
2.55	3.91e-02	GO:0010604	positive regulation of macromolecule metabolic process
2.45	4.57e-02	GO:0009893	positive regulation of metabolic process
8.50	4.62e-02	GO:0002221	pattern recognition receptor signaling pathway

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.79	4.73e-07	GO:0005634	nucleus
1.39	4.30e-04	GO:0043231	intracellular membrane-bounded organelle
1.39	4.56e-04	GO:0043227	membrane-bounded organelle
1.33	9.01e-04	GO:0043229	intracellular organelle
1.33	9.94e-04	GO:0043226	organelle
1.25	2.95e-03	GO:0044424	intracellular part
1.23	6.15e-03	GO:0005622	intracellular

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
4.62	2.86e-12	GO:0001071	nucleic acid binding transcription factor activity
4.62	2.86e-12	GO:0003700	sequence-specific DNA binding transcription factor activity
4.71	2.31e-08	GO:0043565	sequence-specific DNA binding
2.50	5.35e-07	GO:0003677	DNA binding
1.96	1.07e-04	GO:0003676	nucleic acid binding
2.92	6.12e-04	GO:0030528	transcription regulator activity
3.06	1.35e-02	GO:0046983	protein dimerization activity
29.09	1.61e-02	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
4.62	1.80e-02	GO:0003702	RNA polymerase II transcription factor activity
27.01	2.04e-02	GO:0033549	MAP kinase phosphatase activity