Motif ID: BACH2.p2

Z-value: 0.808


Transcription factors associated with BACH2.p2:

Gene SymbolEntrez IDGene Name
BACH2 60468 BTB and CNC homology 1, basic leucine zipper transcription factor 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
BACH2hg19_v1_chr6_-_91006580_910066440.422.7e-01Click!


Activity profile for motif BACH2.p2.

activity profile for motif BACH2.p2


Sorted Z-values histogram for motif BACH2.p2

Sorted Z-values for motif BACH2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of BACH2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_156675237 1.231 NM_001878
NM_001199723
CRABP2

cellular retinoic acid binding protein 2

chr4_+_74606222 1.140 NM_000584
IL8
interleukin 8
chr12_-_58159386 1.111 CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr19_-_46285645 1.002 DMPK
dystrophia myotonica-protein kinase
chr1_-_11918889 0.898 NM_002521
NPPB
natriuretic peptide B
chr19_+_49376488 0.830 PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr7_+_1577118 0.723 MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr19_+_38794800 0.712 NM_033520
C19orf33
chromosome 19 open reading frame 33
chr11_-_65667809 0.651 FOSL1
FOS-like antigen 1
chr19_-_51587466 0.641 NM_022046
KLK14
kallikrein-related peptidase 14
chr19_-_3969734 0.576 NM_001348
DAPK3
death-associated protein kinase 3
chr16_-_122573 0.571 NM_022450
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr17_-_72968790 0.528 NM_030630
C17orf28
chromosome 17 open reading frame 28
chr16_+_83986826 0.487 NM_182981
OSGIN1
oxidative stress induced growth inhibitor 1
chr22_+_22676814 0.484


chr21_+_30517897 0.479 C21orf7
chromosome 21 open reading frame 7
chr20_-_1309782 0.475 SDCBP2
syndecan binding protein (syntenin) 2
chr19_-_46285752 0.468 NM_001081560
NM_001081562
NM_004409
DMPK


dystrophia myotonica-protein kinase


chr16_-_75301950 0.463 NM_001170715
BCAR1
breast cancer anti-estrogen resistance 1
chr1_+_27719151 0.457 NM_005281
GPR3
G protein-coupled receptor 3
chr11_-_67141647 0.456 NM_001166212
CLCF1
cardiotrophin-like cytokine factor 1
chr5_+_179247841 0.423 NM_003900
SQSTM1
sequestosome 1
chr10_+_104155431 0.417 NM_002502
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr5_+_179247911 0.412 SQSTM1
sequestosome 1
chr11_-_65430427 0.411 NM_001145138
NM_001243984
NM_001243985
NM_021975
RELA



v-rel reticuloendotheliosis viral oncogene homolog A (avian)



chr8_-_103666018 0.406 NM_001032282
KLF10
Kruppel-like factor 10
chr5_+_179247903 0.403 SQSTM1
sequestosome 1
chr17_-_7123368 0.403 NM_001365
DLG4
discs, large homolog 4 (Drosophila)
chr3_-_48632592 0.384 NM_000094
COL7A1
collagen, type VII, alpha 1
chr9_-_34662629 0.379 NM_006664
CCL27
chemokine (C-C motif) ligand 27
chr2_+_87754991 0.370 LINC00152
long intergenic non-protein coding RNA 152
chr12_-_15114495 0.367 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr1_+_223889253 0.359 NM_001146068
CAPN2
calpain 2, (m/II) large subunit
chr10_+_121410751 0.355 NM_004281
BAG3
BCL2-associated athanogene 3
chr10_+_121410936 0.353 BAG3
BCL2-associated athanogene 3
chr3_-_187454247 0.346 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr15_+_89182038 0.328 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr22_-_23974486 0.328 NM_016449
C22orf43
chromosome 22 open reading frame 43
chr11_-_65667860 0.327 NM_005438
FOSL1
FOS-like antigen 1
chr16_-_75272979 0.325 NM_001170721
BCAR1
breast cancer anti-estrogen resistance 1
chr10_+_121411086 0.323 BAG3
BCL2-associated athanogene 3
chrX_-_48937560 0.321 NM_001029896
WDR45
WD repeat domain 45
chr17_+_79651072 0.315 HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr16_-_4664780 0.314 FAM100A
family with sequence similarity 100, member A
chr15_-_80263460 0.311 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr19_-_46285746 0.306 DMPK
dystrophia myotonica-protein kinase
chr5_+_150020201 0.306 NM_001109974
NM_007286
SYNPO

synaptopodin

chr6_-_149806116 0.301 NM_207360
ZC3H12D
zinc finger CCCH-type containing 12D
chr11_-_65667858 0.300 FOSL1
FOS-like antigen 1
chr17_+_7123149 0.298 NM_000018
NM_001033859
ACADVL

acyl-CoA dehydrogenase, very long chain

chr18_+_55888750 0.293 NM_001144966
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr2_+_28615771 0.291 NM_005253
FOSL2
FOS-like antigen 2
chrX_-_48937457 0.288 WDR45
WD repeat domain 45
chr10_+_121411042 0.287 BAG3
BCL2-associated athanogene 3
chr1_-_935352 0.283 HES4
hairy and enhancer of split 4 (Drosophila)
chrX_+_12993224 0.282 NM_021109
TMSB4X
thymosin beta 4, X-linked
chr1_+_19638739 0.279 NM_001040125
NM_001040126
NM_017765
PQLC2


PQ loop repeat containing 2


chr10_+_121410891 0.275 BAG3
BCL2-associated athanogene 3
chr9_-_34397786 0.274 NM_032596
C9orf24
chromosome 9 open reading frame 24
chr17_-_18907988 0.265 NM_001039999
FAM83G
family with sequence similarity 83, member G
chr1_+_161494035 0.262 NM_002155
HSPA6
heat shock 70kDa protein 6 (HSP70B')
chr18_-_74207145 0.259 NM_014643
ZNF516
zinc finger protein 516
chr12_-_56236614 0.257 NM_002429
MMP19
matrix metallopeptidase 19
chr7_+_143078457 0.255 ZYX
zyxin
chr10_+_5238756 0.252 NM_001818
AKR1C4
aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)
chr7_+_143078444 0.250 ZYX
zyxin
chr12_-_57914287 0.250 NM_001195053
NM_001195054
NM_001195055
NM_001195056
NM_001195057
NM_004083
DDIT3





DNA-damage-inducible transcript 3





chr2_+_113875469 0.249 NM_000577
NM_173841
NM_173843
IL1RN


interleukin 1 receptor antagonist


chr10_+_121411071 0.248 BAG3
BCL2-associated athanogene 3
chr4_+_671710 0.244 NM_002477
MYL5
myosin, light chain 5, regulatory
chr11_-_2950593 0.241 NM_003311
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr6_-_31745048 0.240 NM_025258
C6orf27
chromosome 6 open reading frame 27
chr15_+_78558522 0.240 NM_001130183
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr21_+_30452872 0.240 NM_020152
C21orf7
chromosome 21 open reading frame 7
chr7_+_143078395 0.237 ZYX
zyxin
chr1_+_223900061 0.234 NM_001748
CAPN2
calpain 2, (m/II) large subunit
chr14_+_68168602 0.232 NM_152443
RDH12
retinol dehydrogenase 12 (all-trans/9-cis/11-cis)
chr10_+_104154228 0.229 NM_001077493
NM_001077494
NFKB2

nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)

chr18_+_55888799 0.228 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr12_-_102591547 0.227 NM_002674
PMCH
pro-melanin-concentrating hormone
chr2_-_73316782 0.226 RAB11FIP5
RAB11 family interacting protein 5 (class I)
chr11_-_65430214 0.226 RELA
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr12_-_15815073 0.225 EPS8
epidermal growth factor receptor pathway substrate 8
chr19_-_44008984 0.225 NM_198850
PHLDB3
pleckstrin homology-like domain, family B, member 3
chr18_+_32290195 0.224 NM_001198941
NM_032978
DTNA

dystrobrevin, alpha

chr1_+_36621457 0.224 MAP7D1
MAP7 domain containing 1
chr17_+_7123246 0.222 ACADVL
acyl-CoA dehydrogenase, very long chain
chrX_-_48900752 0.222 TFE3
transcription factor binding to IGHM enhancer 3
chr3_-_48601200 0.221 NM_033199
UCN2
urocortin 2
chr7_+_143078447 0.221 ZYX
zyxin
chr1_-_45308603 0.221 NM_001166292
NM_003738
PTCH2

patched 2

chr1_+_36621751 0.220 NM_018067
MAP7D1
MAP7 domain containing 1
chr16_-_4664894 0.219 NM_145253
FAM100A
family with sequence similarity 100, member A
chr3_-_114478117 0.217 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr16_+_67571342 0.216 NM_001193524
FAM65A
family with sequence similarity 65, member A
chr17_+_79650961 0.216 NM_004712
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr7_+_143058794 0.212 ZYX
zyxin
chr1_-_179112178 0.209 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr2_+_87755059 0.207 LINC00152
long intergenic non-protein coding RNA 152
chr2_-_85641128 0.206 CAPG
capping protein (actin filament), gelsolin-like
chr8_+_22210311 0.205 PIWIL2
piwi-like 2 (Drosophila)
chr2_+_220144024 0.205 NM_001039550
NM_006736
DNAJB2

DnaJ (Hsp40) homolog, subfamily B, member 2

chr19_+_7953380 0.204 NM_025061
LRRC8E
leucine rich repeat containing 8 family, member E
chr7_-_107643330 0.203 NM_002291
LAMB1
laminin, beta 1
chr17_-_3461030 0.202 TRPV3
transient receptor potential cation channel, subfamily V, member 3
chr22_+_20861964 0.202 MED15
mediator complex subunit 15
chr7_+_143078358 0.200 NM_001010972
NM_003461
ZYX

zyxin

chr1_-_84972259 0.200 NM_005274
GNG5
guanine nucleotide binding protein (G protein), gamma 5
chr3_-_114343791 0.200 NM_001164346
ZBTB20
zinc finger and BTB domain containing 20
chr16_+_67563539 0.200 NM_001193523
FAM65A
family with sequence similarity 65, member A
chr2_+_28615695 0.196 FOSL2
FOS-like antigen 2
chr1_-_1690080 0.195 NM_001198995
NADK
NAD kinase
chr6_-_41673677 0.194 TFEB
transcription factor EB
chr11_-_128894008 0.193 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr18_+_55888838 0.192 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr19_-_36019194 0.187 NM_001166034
NM_001166035
NM_198538
SBSN


suprabasin


chr22_+_20861859 0.186 MED15
mediator complex subunit 15
chr7_+_150065330 0.185 REPIN1
replication initiator 1
chr9_-_123688352 0.185 TRAF1
TNF receptor-associated factor 1
chr6_+_30875962 0.183 NM_001517
GTF2H4
general transcription factor IIH, polypeptide 4, 52kDa
chr3_-_49395697 0.183 GPX1
glutathione peroxidase 1
chr22_+_20861898 0.183 MED15
mediator complex subunit 15
chr17_-_55980749 0.182 NM_017949
CUEDC1
CUE domain containing 1
chrX_-_48900932 0.181 NM_006521
TFE3
transcription factor binding to IGHM enhancer 3
chr7_+_100027253 0.180 NM_019606
MEPCE
methylphosphate capping enzyme
chr5_-_75919051 0.179 NM_004101
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr6_-_30654978 0.179 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr16_+_30968614 0.178 NM_014712
SETD1A
SET domain containing 1A
chr16_+_56642477 0.178 NM_005953
MT2A
metallothionein 2A
chr1_-_84971882 0.177 GNG5
guanine nucleotide binding protein (G protein), gamma 5
chr1_+_36554452 0.177 NM_017825
ADPRHL2
ADP-ribosylhydrolase like 2
chr17_-_7493389 0.177 NM_006942
SOX15
SRY (sex determining region Y)-box 15
chr20_-_17539480 0.177 NM_001161705
BFSP1
beaded filament structural protein 1, filensin
chr17_-_18162018 0.174 FLII
flightless I homolog (Drosophila)
chr17_-_18161869 0.174 FLII
flightless I homolog (Drosophila)
chr22_+_20861886 0.172 MED15
mediator complex subunit 15
chr16_+_22308722 0.172 NM_018119
POLR3E
polymerase (RNA) III (DNA directed) polypeptide E (80kD)
chr11_-_65150107 0.172 NM_001077241
NM_182556
SLC25A45

solute carrier family 25, member 45

chr3_+_141087298 0.171 ZBTB38
zinc finger and BTB domain containing 38
chr10_-_31288420 0.170 NM_001143769
ZNF438
zinc finger protein 438
chr6_-_149806025 0.170 ZC3H12D
zinc finger CCCH-type containing 12D
chr3_+_183903970 0.169 ABCF3
ATP-binding cassette, sub-family F (GCN20), member 3
chr19_+_3728373 0.169 NM_014428
TJP3
tight junction protein 3 (zona occludens 3)
chr8_-_38008332 0.168 NM_000349
STAR
steroidogenic acute regulatory protein
chr3_-_49823626 0.166 NM_001242829
IP6K1
inositol hexakisphosphate kinase 1
chr22_+_20861884 0.165 NM_001003891
NM_015889
MED15

mediator complex subunit 15

chr17_+_79651042 0.164 HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr1_-_157108132 0.164 ETV3
ets variant 3
chr1_+_223900328 0.162 CAPN2
calpain 2, (m/II) large subunit
chr15_+_59904090 0.161 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr17_+_79651035 0.161 HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr10_+_17270469 0.161 VIM
vimentin
chr17_+_79651052 0.160


chr22_+_20861875 0.160 MED15
mediator complex subunit 15
chr7_+_143078399 0.159 ZYX
zyxin
chr10_+_17270257 0.159 NM_003380
VIM
vimentin
chr13_-_30423599 0.159 UBL3
ubiquitin-like 3
chr15_+_59903980 0.156 NM_004751
GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr10_-_73611050 0.156 NM_001042465
NM_001042466
NM_002778
PSAP


prosaposin


chr6_-_30655078 0.156 NM_001134870
PPP1R18
protein phosphatase 1, regulatory subunit 18
chr11_-_62607043 0.155 WDR74
WD repeat domain 74
chr12_+_10365415 0.154 NM_031412
GABARAPL1
GABA(A) receptor-associated protein like 1
chr1_+_17866276 0.154 NM_018125
ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr11_+_44087728 0.153 NM_001127219
NM_032592
ACCS

1-aminocyclopropane-1-carboxylate synthase homolog (Arabidopsis)(non-functional)

chr7_-_7758237 0.152 NM_002947
RPA3
replication protein A3, 14kDa
chr18_-_47376156 0.151 MYO5B
myosin VB
chr12_-_58165877 0.151 NM_005371
NM_023033
METTL1

methyltransferase like 1

chr17_+_48712115 0.149 NM_001144070
NM_003786
ABCC3

ATP-binding cassette, sub-family C (CFTR/MRP), member 3

chr17_-_79881304 0.148 NM_032711
MAFG
v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr16_+_30419363 0.148 ZNF771
zinc finger protein 771
chr20_+_44034632 0.148 NM_001197139
NM_001048221
NM_001048222
NM_001197140
NM_018478
DBNDD2




dysbindin (dystrobrevin binding protein 1) domain containing 2




chr3_+_183903862 0.148 NM_018358
ABCF3
ATP-binding cassette, sub-family F (GCN20), member 3
chr3_-_49395751 0.147 NM_000581
NM_201397
GPX1

glutathione peroxidase 1

chr1_-_27816676 0.147 NM_001201404
NM_006990
WASF2

WAS protein family, member 2

chr3_-_196065243 0.147 NM_001204897
NM_001204898
NM_138461
TM4SF19


transmembrane 4 L six family member 19


chr20_+_44035203 0.145 NM_001048223
NM_001048224
DBNDD2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chr16_-_75272524 0.145 BCAR1
breast cancer anti-estrogen resistance 1
chr22_-_39151457 0.143 NM_001199580
SUN2
Sad1 and UNC84 domain containing 2
chr14_-_94855120 0.141 NM_000295
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr6_-_159239254 0.138 EZR
ezrin
chr5_-_90610218 0.137 LOC100505994
uncharacterized LOC100505994
chr4_-_987163 0.137 NM_022042
NM_134425
NM_213613
SLC26A1


solute carrier family 26 (sulfate transporter), member 1


chr11_+_68671375 0.137 IGHMBP2
immunoglobulin mu binding protein 2
chr10_-_73611041 0.137 PSAP
prosaposin
chr22_-_39152008 0.136 NM_001199579
NM_015374
SUN2

Sad1 and UNC84 domain containing 2

chr11_+_394199 0.136 NM_007183
PKP3
plakophilin 3
chr11_-_71781091 0.135 NUMA1
nuclear mitotic apparatus protein 1
chr10_-_73611005 0.135 PSAP
prosaposin
chr12_+_122614486 0.134 MLXIP
MLX interacting protein
chr20_-_1309809 0.133 NM_080489
SDCBP2
syndecan binding protein (syntenin) 2
chr7_+_48128225 0.133 NM_181597
UPP1
uridine phosphorylase 1
chr13_-_41593405 0.133 ELF1
E74-like factor 1 (ets domain transcription factor)
chr22_-_39151979 0.132 SUN2
Sad1 and UNC84 domain containing 2
chr1_-_36817157 0.132


chr1_-_27816667 0.131 WASF2
WAS protein family, member 2
chr17_-_72889704 0.130 NM_178128
FADS6
fatty acid desaturase domain family, member 6
chr5_-_141030934 0.129 FCHSD1
FCH and double SH3 domains 1
chr2_-_145274916 0.128 ZEB2
zinc finger E-box binding homeobox 2
chr12_-_53343607 0.128 KRT8
keratin 8
chr3_+_187930720 0.127 NM_005578
LPP
LIM domain containing preferred translocation partner in lipoma

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
161.03 2.31e-03 GO:0006775 fat-soluble vitamin metabolic process
70.56 1.22e-02 GO:0032103 positive regulation of response to external stimulus
62.74 1.54e-02 GO:0006766 vitamin metabolic process
57.93 1.81e-02 GO:0007050 cell cycle arrest
52.56 2.20e-02 GO:0032496 response to lipopolysaccharide
47.77 2.66e-02 GO:0002237 response to molecule of bacterial origin
47.44 2.70e-02 GO:0042445 hormone metabolic process
36.32 4.61e-02 GO:0010817 regulation of hormone levels

Nothing significant found in compartment category.

Nothing significant found in function category.