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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: E2F1..5.p2

Z-value: 5.475

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_+_16080639	19.746	NM_005378	MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr2_+_16080559	18.521		MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr19_+_4909447	12.528	NM_001048201	UHRF1	ubiquitin-like with PHD and ring finger domains 1
chr1_-_23857711	10.911	NM_004091	E2F2	E2F transcription factor 2
chr1_-_23857284	10.289		E2F2	E2F transcription factor 2
chr20_-_5100443	9.514	NM_182649	PCNA	proliferating cell nuclear antigen
chr6_+_27100784	9.346	NM_021064	HIST1H2AG	histone cluster 1, H2ag
chr15_+_66994669	7.897	NM_005585	SMAD6	SMAD family member 6
chr2_-_136633934	7.883		MCM6	minichromosome maintenance complex component 6
chr19_+_4910166	7.737		UHRF1	ubiquitin-like with PHD and ring finger domains 1
chr2_-_136634002	7.666	NM_005915	MCM6	minichromosome maintenance complex component 6
chr15_-_64673569	7.241	NM_001029989 NM_014736	KIAA0101	KIAA0101
chr12_-_77459198	7.114	NM_203394	E2F7	E2F transcription factor 7
chr7_+_129074235	6.078	NM_001134336 NM_020704	FAM40B	family with sequence similarity 40, member B
chr15_+_66995414	6.055		SMAD6	SMAD family member 6
chr2_+_232573226	5.685	NM_001099285 NM_002823	PTMA	prothymosin, alpha
chr1_-_36235422	5.482	NM_001190481 NM_022111	CLSPN	claspin
chrX_-_131623994	5.393	NM_001170704	MBNL3	muscleblind-like 3 (Drosophila)
chr11_-_19263144	5.367		E2F8	E2F transcription factor 8
chr6_-_52149472	5.217		MCM3	minichromosome maintenance complex component 3
chr22_+_35796104	5.189	NM_006739	MCM5	minichromosome maintenance complex component 5
chr6_-_52149541	5.091	NM_002388	MCM3	minichromosome maintenance complex component 3
chr6_-_27775683	5.035	NM_003519	HIST1H2BL	histone cluster 1, H2bl
chr7_+_94285736	5.019		PEG10	paternally expressed 10
chr7_+_94285676	4.985	NM_001172437 NM_001172438	PEG10	paternally expressed 10
chr6_-_52149516	4.942		MCM3	minichromosome maintenance complex component 3
chr22_+_35796154	4.874		MCM5	minichromosome maintenance complex component 5
chr19_+_4910339	4.848	NM_013282	UHRF1	ubiquitin-like with PHD and ring finger domains 1
chr6_+_27833033	4.797	NM_003511	HIST1H2AI HIST1H2AL	histone cluster 1, H2ai histone cluster 1, H2al
chr6_+_27114860	4.771	NM_080596	HIST1H2AH	histone cluster 1, H2ah
chr6_+_135502521	4.770		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr8_-_95907423	4.768	NM_057749	CCNE2	cyclin E2
chr16_+_67596309	4.767	NM_001191022 NM_006565	CTCF	CCCTC-binding factor (zinc finger protein)
chr7_+_94285620	4.734	NM_001040152 NM_001184961 NM_001184962 NM_015068	PEG10	paternally expressed 10
chr6_+_135502445	4.701	NM_001130172 NM_001130173 NM_001161656 NM_001161657 NM_001161658 NM_001161659 NM_001161660 NM_005375	MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr2_+_232573249	4.644		PTMA	prothymosin, alpha
chr20_-_44563573	4.634		FLJ40606	uncharacterized LOC643549
chr15_+_40763159	4.620	NM_130468	CHST14	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr5_+_36152221	4.486		SKP2	S-phase kinase-associated protein 2 (p45)
chr4_-_146859960	4.441
chr6_+_27775898	4.425	NM_003509	HIST1H2AI HIST1H2AM HIST1H3F	histone cluster 1, H2ai histone cluster 1, H2am histone cluster 1, H3f
chr2_+_10262853	4.386	NM_001034	RRM2	ribonucleotide reductase M2
chr3_+_127317274	4.287		MCM2	minichromosome maintenance complex component 2
chr16_+_58426297	4.201	NM_001126129 NM_001126130 NM_022770	GINS3	GINS complex subunit 3 (Psf3 homolog)
chr3_+_127317271	4.187		MCM2	minichromosome maintenance complex component 2
chr20_-_44563684	4.164		FLJ40606	uncharacterized LOC643549
chr5_+_36152142	4.155	NM_001243120 NM_005983 NM_032637	SKP2	S-phase kinase-associated protein 2 (p45)
chr11_-_19262424	4.087	NM_024680	E2F8	E2F transcription factor 8
chr20_-_35724330	4.059		RBL1	retinoblastoma-like 1 (p107)
chr2_+_10262694	4.042	NM_001165931	RRM2	ribonucleotide reductase M2
chr13_-_41768533	3.985	NM_032138	KBTBD7	kelch repeat and BTB (POZ) domain containing 7
chr3_+_127317212	3.954	NM_004526	MCM2	minichromosome maintenance complex component 2
chr22_+_35796294	3.927		MCM5	minichromosome maintenance complex component 5
chr16_-_85722503	3.904		GINS2	GINS complex subunit 2 (Psf2 homolog)
chr16_-_85722587	3.793	NM_016095	GINS2	GINS complex subunit 2 (Psf2 homolog)
chr8_+_48873533	3.772		MCM4	minichromosome maintenance complex component 4
chr13_-_41706587	3.716	NM_152903	KBTBD6	kelch repeat and BTB (POZ) domain containing 6
chr10_+_13203547	3.710	NM_018518 NM_182751	MCM10	minichromosome maintenance complex component 10
chr12_-_133263988	3.686		POLE	polymerase (DNA directed), epsilon
chr13_-_41768392	3.684		KBTBD7	kelch repeat and BTB (POZ) domain containing 7
chr8_+_48873446	3.533		MCM4	minichromosome maintenance complex component 4
chr11_+_77850824	3.459		LOC100289388	uncharacterized LOC100289388
chr13_+_114239047	3.454	NM_007111	TFDP1	transcription factor Dp-1
chr6_-_153304093	3.449	NM_012177	FBXO5	F-box protein 5
chr20_-_35724401	3.343	NM_002895 NM_183404	RBL1	retinoblastoma-like 1 (p107)
chr15_+_41221530	3.317	NM_019074	DLL4	delta-like 4 (Drosophila)
chr10_-_21805715	3.294		C10orf140	chromosome 10 open reading frame 140
chr20_+_5891973	3.272	NM_001819	CHGB	chromogranin B (secretogranin 1)
chr12_+_109535377	3.256	NM_080911	UNG	uracil-DNA glycosylase
chr7_-_44887697	3.227	NM_012412 NM_138635 NM_201436 NM_201516 NM_201517	H2AFV	H2A histone family, member V
chr5_+_93954352	3.176	NM_032290	ANKRD32	ankyrin repeat domain 32
chr17_-_35293920	3.152
chr8_+_48873510	3.150		MCM4	minichromosome maintenance complex component 4
chr2_+_85766291	3.099		MAT2A	methionine adenosyltransferase II, alpha
chr12_+_109535922	3.084	NM_003362	UNG	uracil-DNA glycosylase
chr5_-_101631965	3.079	NM_180991	SLCO4C1	solute carrier organic anion transporter family, member 4C1
chr19_-_6502224	3.016	NM_006087	TUBB4A	tubulin, beta 4A class IVa
chr6_+_31126114	3.001	NM_001077511 NM_007109	TCF19	transcription factor 19
chr11_+_74303626	2.998	NM_006591	POLD3	polymerase (DNA-directed), delta 3, accessory subunit
chr1_+_212209129	2.976		DTL	denticleless homolog (Drosophila)
chr17_+_38444130	2.975		CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr6_+_31126340	2.970		TCF19	transcription factor 19
chr4_+_178231013	2.937		NEIL3	nei endonuclease VIII-like 3 (E. coli)
chr20_-_32274070	2.933		E2F1	E2F transcription factor 1
chr17_+_38444134	2.881	NM_001254	CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr1_+_212208918	2.878	NM_016448	DTL	denticleless homolog (Drosophila)
chr1_+_212209112	2.873		DTL	denticleless homolog (Drosophila)
chr22_-_38966066	2.859	NM_007068	DMC1	DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)
chr10_-_53459309	2.829	NM_015235	CSTF2T	cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
chr16_-_74401792	2.802
chr2_+_174219537	2.750	NM_031942 NM_145810	CDCA7	cell division cycle associated 7
chr6_-_116575170	2.748	NM_021648	TSPYL4	TSPY-like 4
chr3_-_123167391	2.714	NM_183357	ADCY5	adenylate cyclase 5
chr1_-_205719309	2.643
chr4_+_178230979	2.596	NM_018248	NEIL3	nei endonuclease VIII-like 3 (E. coli)
chr15_+_91260575	2.575	NM_000057	BLM	Bloom syndrome, RecQ helicase-like
chr11_+_65029312	2.574	NM_002689	POLA2	polymerase (DNA directed), alpha 2 (70kD subunit)
chr1_-_205719340	2.560	NM_022731	NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr1_-_32801606	2.560	NM_023009	MARCKSL1	MARCKS-like 1
chr10_-_21785873	2.543		C10orf114	chromosome 10 open reading frame 114
chr9_+_86595636	2.538	NM_024945	RMI1	RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae)
chr7_-_44887567	2.538		H2AFV	H2A histone family, member V
chr20_-_32274154	2.528	NM_005225	E2F1	E2F transcription factor 1
chr3_-_169381417	2.526	NM_001205194 NM_004991	MECOM	MDS1 and EVI1 complex locus
chr17_+_38444151	2.517		CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr6_+_35181721	2.513		SCUBE3	signal peptide, CUB domain, EGF-like 3
chr6_+_27861202	2.510	NM_003527	HIST1H2BO	histone cluster 1, H2bo
chr1_+_242011544	2.498		EXO1	exonuclease 1
chr5_-_79950307	2.495		DHFR	dihydrofolate reductase
chr19_-_36705982	2.488	NM_001042474	ZNF565	zinc finger protein 565
chr12_-_12849120	2.456	NM_006143	GPR19	G protein-coupled receptor 19
chr8_+_26435590	2.423		DPYSL2	dihydropyrimidinase-like 2
chr2_+_48010220	2.420	NM_000179	MSH6	mutS homolog 6 (E. coli)
chr1_+_26798961	2.403		HMGN2	high mobility group nucleosomal binding domain 2
chr5_+_126626455	2.400	NM_032446	MEGF10	multiple EGF-like-domains 10
chr22_+_20104810	2.392	NM_002882	RANBP1	RAN binding protein 1
chr16_+_29817426	2.391		MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)
chr8_-_120868034	2.364	NM_024094	DSCC1	defective in sister chromatid cohesion 1 homolog (S. cerevisiae)
chr12_+_70759974	2.356	NM_014505	KCNMB4	potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr1_-_23670743	2.352	NM_001102397 NM_001102398 NM_001102399 NM_005826	HNRNPR	heterogeneous nuclear ribonucleoprotein R
chr7_-_44887663	2.322		H2AFV	H2A histone family, member V
chr1_+_242011471	2.312	NM_130398	EXO1	exonuclease 1
chr3_-_44803095	2.311	NM_020696	KIAA1143	KIAA1143
chr7_-_44887620	2.295		H2AFV	H2A histone family, member V
chr10_-_25241504	2.294	NM_020200	PRTFDC1	phosphoribosyl transferase domain containing 1
chr1_-_26185847	2.283	NM_024037	C1orf135	chromosome 1 open reading frame 135
chr10_-_21786186	2.281		C10orf114	chromosome 10 open reading frame 114
chr1_-_205719157	2.270		NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr9_+_116638544	2.265	NM_133374	ZNF618	zinc finger protein 618
chr13_+_114238978	2.264		TFDP1	transcription factor Dp-1
chr17_-_56084514	2.245		SRSF1	serine/arginine-rich splicing factor 1
chr10_-_21786205	2.232	NM_001010911	C10orf114	chromosome 10 open reading frame 114
chr1_-_205719273	2.215		NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr20_-_60982334	2.208	NM_031215	CABLES2	Cdk5 and Abl enzyme substrate 2
chr10_+_73723992	2.199	NM_004273	CHST3	carbohydrate (chondroitin 6) sulfotransferase 3
chr10_-_13390189	2.198	NM_001195602 NM_001195604 NM_012247	SEPHS1	selenophosphate synthetase 1
chr10_+_99473478	2.194		MARVELD1	MARVEL domain containing 1
chr1_-_205719078	2.185		NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr1_+_2518071	2.184	NM_001195736 NM_001195737 NM_001195738 NM_001195740 NM_001195741 NM_152371	FAM213B	family with sequence similarity 213, member B
chr1_-_26232643	2.175	NM_203401	STMN1	stathmin 1
chr5_-_79950348	2.173		DHFR	dihydrofolate reductase
chr1_-_205719129	2.172		NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr16_+_87636492	2.170	NM_020655	JPH3	junctophilin 3
chr3_-_14989399	2.145		LOC100505641	uncharacterized LOC100505641
chr1_+_26798901	2.145	NM_005517	HMGN2	high mobility group nucleosomal binding domain 2
chr14_+_85999464	2.136
chr13_+_115079943	2.129	NM_001164144 NM_001164145 NM_032436	CHAMP1	chromosome alignment maintaining phosphoprotein 1
chrX_-_119763804	2.120	NM_001011551 NM_152692	C1GALT1C1	C1GALT1-specific chaperone 1
chr13_+_34392205	2.113	NM_002915 NM_181558	RFC3	replication factor C (activator 1) 3, 38kDa
chr1_+_33116748	2.105	NM_001135255 NM_005610 NM_001135256	RBBP4	retinoblastoma binding protein 4
chr16_+_84150634	2.101		LOC729887	uncharacterized LOC729887
chr2_+_47630246	2.099	NM_000251	MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr19_+_45909466	2.089	NM_012099	CD3EAP	CD3e molecule, epsilon associated protein
chr13_+_34392254	2.063		RFC3	replication factor C (activator 1) 3, 38kDa
chr17_-_56084571	2.061		SRSF1	serine/arginine-rich splicing factor 1
chr1_+_78511747	2.052		GIPC2	GIPC PDZ domain containing family, member 2
chr15_-_66648991	2.049	NM_017858	TIPIN	TIMELESS interacting protein
chr22_+_20105145	2.043		RANBP1	RAN binding protein 1
chr2_+_172950207	2.007	NM_001038493 NM_178120	DLX1	distal-less homeobox 1
chrX_+_24712063	2.007	NM_016937	POLA1	polymerase (DNA directed), alpha 1, catalytic subunit
chr17_+_57642885	2.004	NM_001166301 NM_024612	DHX40	DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr11_-_118966103	2.003		H2AFX	H2A histone family, member X
chr10_+_99473456	2.001	NM_031484	MARVELD1	MARVEL domain containing 1
chr11_-_118966175	1.997	NM_002105	H2AFX	H2A histone family, member X
chr17_-_7197811	1.987		YBX2	Y box binding protein 2
chr7_-_99699030	1.986		MCM7	minichromosome maintenance complex component 7
chr10_-_73848263	1.984		SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr15_+_80987609	1.978	NM_021214	FAM108C1	family with sequence similarity 108, member C1
chr7_-_99698916	1.970		MCM7	minichromosome maintenance complex component 7
chr3_-_148804122	1.957	NM_003071 NM_139048	HLTF	helicase-like transcription factor
chr6_+_26021906	1.953	NM_003538	HIST1H4A	histone cluster 1, H4a
chr7_-_99698993	1.951		MCM7	minichromosome maintenance complex component 7
chr14_-_74551159	1.951	NM_005589	ALDH6A1	aldehyde dehydrogenase 6 family, member A1
chr9_+_100745584	1.945		ANP32B	acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr3_-_196230365	1.938	NM_152617	RNF168	ring finger protein 168
chr6_+_52535874	1.937	NM_014051	TMEM14A	transmembrane protein 14A
chr20_+_5931297	1.932	NM_032485 NM_182802	MCM8	minichromosome maintenance complex component 8
chr20_+_25388328	1.932		GINS1	GINS complex subunit 1 (Psf1 homolog)
chr3_-_107809754	1.931	NM_001777 NM_198793	CD47	CD47 molecule
chr22_+_20105095	1.923		RANBP1	RAN binding protein 1
chr14_+_93673622	1.921		UBR7	ubiquitin protein ligase E3 component n-recognin 7 (putative)
chr22_-_39239733	1.913
chr22_+_20105068	1.906		RANBP1	RAN binding protein 1
chr3_+_44803208	1.903	NM_020242	KIF15	kinesin family member 15
chrX_+_24712043	1.901		POLA1	polymerase (DNA directed), alpha 1, catalytic subunit
chr5_-_36876730	1.893		LOC646719	uncharacterized LOC646719
chr3_+_44803280	1.893		KIF15	kinesin family member 15
chr14_+_105941061	1.889	NM_001312	CRIP2	cysteine-rich protein 2
chr8_+_26435466	1.885		DPYSL2	dihydropyrimidinase-like 2
chr5_+_126113050	1.885		LMNB1	lamin B1
chr19_+_30302861	1.882	NM_001238	CCNE1	cyclin E1
chr10_+_96305521	1.879	NM_018063	HELLS	helicase, lymphoid-specific
chr16_-_74401991	1.877		LOC283922	pyruvate dehydrogenase phosphatase regulatory subunit pseudogene
chr5_-_126409171	1.858	NM_001164478 NM_001164479	C5orf63	chromosome 5 open reading frame 63
chr11_+_4115923	1.840	NM_001033	RRM1	ribonucleotide reductase M1
chr22_+_20105076	1.837		RANBP1	RAN binding protein 1
chr14_+_93673583	1.833		UBR7	ubiquitin protein ligase E3 component n-recognin 7 (putative)
chr14_+_93673628	1.833		UBR7	ubiquitin protein ligase E3 component n-recognin 7 (putative)
chr14_-_21852161	1.830		SUPT16H	suppressor of Ty 16 homolog (S. cerevisiae)
chr3_+_40547529	1.821	NM_175888	ZNF620	zinc finger protein 620

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
7.04	1.16e-30	GO:0006259	DNA metabolic process
13.53	1.45e-28	GO:0006260	DNA replication
20.11	2.84e-20	GO:0006261	DNA-dependent DNA replication
4.24	1.02e-19	GO:0007049	cell cycle
5.05	2.11e-18	GO:0022403	cell cycle phase
7.38	1.55e-16	GO:0051325	interphase
4.38	3.70e-16	GO:0022402	cell cycle process
7.29	8.54e-16	GO:0051329	interphase of mitotic cell cycle
31.99	1.13e-15	GO:0006271	DNA strand elongation involved in DNA replication
29.85	3.99e-15	GO:0022616	DNA strand elongation
10.59	2.03e-14	GO:0000082	G1/S transition of mitotic cell cycle
2.39	4.89e-14	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.59	1.35e-13	GO:0090304	nucleic acid metabolic process
4.75	3.43e-13	GO:0000278	mitotic cell cycle
11.63	4.02e-13	GO:0051320	S phase
6.14	4.21e-13	GO:0010564	regulation of cell cycle process
6.04	2.08e-12	GO:0006281	DNA repair
4.40	4.14e-12	GO:0051726	regulation of cell cycle
11.26	4.27e-12	GO:0000084	S phase of mitotic cell cycle
31.99	6.48e-12	GO:0006270	DNA-dependent DNA replication initiation
2.09	4.67e-11	GO:0006807	nitrogen compound metabolic process
2.12	4.69e-11	GO:0034641	cellular nitrogen compound metabolic process
6.94	2.46e-10	GO:0071156	regulation of cell cycle arrest
4.49	3.98e-10	GO:0006974	response to DNA damage stimulus
6.90	9.44e-10	GO:0000075	cell cycle checkpoint
7.78	1.58e-08	GO:0071103	DNA conformation change
8.06	3.36e-08	GO:0006310	DNA recombination
2.49	3.55e-08	GO:0034645	cellular macromolecule biosynthetic process
3.79	3.97e-08	GO:0051276	chromosome organization
2.46	5.72e-08	GO:0009059	macromolecule biosynthetic process
8.57	2.07e-07	GO:0071824	protein-DNA complex subunit organization
10.66	2.10e-07	GO:0000216	M/G1 transition of mitotic cell cycle
25.59	3.45e-07	GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle
7.42	4.55e-07	GO:0051052	regulation of DNA metabolic process
8.45	1.02e-06	GO:0065004	protein-DNA complex assembly
7.11	2.95e-06	GO:0006333	chromatin assembly or disassembly
8.58	3.43e-06	GO:0031497	chromatin assembly
19.69	3.95e-06	GO:0006312	mitotic recombination
2.98	6.00e-06	GO:0033554	cellular response to stress
8.16	6.42e-06	GO:0034728	nucleosome organization
23.57	9.19e-06	GO:0032201	telomere maintenance via semi-conservative replication
1.99	1.12e-05	GO:0044249	cellular biosynthetic process
7.06	1.12e-05	GO:0006323	DNA packaging
31.99	1.21e-05	GO:0071897	DNA biosynthetic process
22.39	1.40e-05	GO:0000722	telomere maintenance via recombination
1.93	2.66e-05	GO:0009058	biosynthetic process
12.00	4.77e-05	GO:0000723	telomere maintenance
11.75	5.77e-05	GO:0032200	telomere organization
11.29	8.31e-05	GO:0051053	negative regulation of DNA metabolic process
1.84	1.07e-04	GO:0071841	cellular component organization or biogenesis at cellular level
1.60	1.10e-04	GO:0044260	cellular macromolecule metabolic process
35.54	1.12e-04	GO:0002566	somatic diversification of immune receptors via somatic mutation
35.54	1.12e-04	GO:0016446	somatic hypermutation of immunoglobulin genes
1.71	1.33e-04	GO:0071840	cellular component organization or biogenesis
1.86	1.35e-04	GO:0071842	cellular component organization at cellular level
1.72	1.45e-04	GO:0016043	cellular component organization
2.16	1.51e-04	GO:0006996	organelle organization
7.65	1.90e-04	GO:0006334	nucleosome assembly
2.93	1.98e-04	GO:0065003	macromolecular complex assembly
2.71	2.62e-04	GO:0043933	macromolecular complex subunit organization
3.80	3.34e-04	GO:0034622	cellular macromolecular complex assembly
14.45	4.10e-04	GO:0010833	telomere maintenance via telomere lengthening
8.00	4.57e-04	GO:0006275	regulation of DNA replication
19.19	4.58e-04	GO:0006298	mismatch repair
19.19	4.58e-04	GO:2000104	negative regulation of DNA-dependent DNA replication
3.28	5.81e-04	GO:0034621	cellular macromolecular complex subunit organization
2.43	6.19e-04	GO:0022607	cellular component assembly
18.28	6.33e-04	GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus
18.28	6.33e-04	GO:0016444	somatic cell DNA recombination
6.46	1.08e-03	GO:0007126	meiosis
6.46	1.08e-03	GO:0051327	M phase of meiotic cell cycle
16.69	1.15e-03	GO:0090329	regulation of DNA-dependent DNA replication
6.40	1.18e-03	GO:0051321	meiotic cell cycle
3.37	1.20e-03	GO:0000279	M phase
2.29	1.24e-03	GO:0044085	cellular component biogenesis
11.79	1.79e-03	GO:0008156	negative regulation of DNA replication
1.74	1.87e-03	GO:0051171	regulation of nitrogen compound metabolic process
15.36	1.96e-03	GO:0002200	somatic diversification of immune receptors
1.61	2.13e-03	GO:0031323	regulation of cellular metabolic process
1.74	2.85e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
19.99	3.55e-03	GO:0006297	nucleotide-excision repair, DNA gap filling
63.97	4.03e-03	GO:0010216	maintenance of DNA methylation
31.99	4.10e-03	GO:0000731	DNA synthesis involved in DNA repair
2.42	4.40e-03	GO:0010605	negative regulation of macromolecule metabolic process
18.82	4.97e-03	GO:0016447	somatic recombination of immunoglobulin gene segments
2.71	5.72e-03	GO:0010558	negative regulation of macromolecule biosynthetic process
1.46	6.27e-03	GO:0043170	macromolecule metabolic process
2.56	7.03e-03	GO:0071844	cellular component assembly at cellular level
1.54	7.90e-03	GO:0019222	regulation of metabolic process
2.73	8.30e-03	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.58	9.15e-03	GO:0080090	regulation of primary metabolic process
2.37	9.75e-03	GO:0031324	negative regulation of cellular metabolic process
1.37	9.77e-03	GO:0044238	primary metabolic process
2.60	1.17e-02	GO:0031327	negative regulation of cellular biosynthetic process
11.29	1.33e-02	GO:0006284	base-excision repair
7.31	1.33e-02	GO:0006302	double-strand break repair
2.99	1.33e-02	GO:0006325	chromatin organization
1.33	1.52e-02	GO:0050794	regulation of cellular process
2.55	1.67e-02	GO:0009890	negative regulation of biosynthetic process
1.58	1.76e-02	GO:0060255	regulation of macromolecule metabolic process
23.26	1.86e-02	GO:0000076	DNA replication checkpoint
23.26	1.86e-02	GO:0032297	negative regulation of DNA-dependent DNA replication initiation
2.66	1.87e-02	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.36	1.96e-02	GO:0044237	cellular metabolic process
14.54	1.99e-02	GO:0016445	somatic diversification of immunoglobulins
2.24	2.04e-02	GO:0009892	negative regulation of metabolic process
2.63	2.28e-02	GO:0051172	negative regulation of nitrogen compound metabolic process
1.66	2.36e-02	GO:0031326	regulation of cellular biosynthetic process
8.00	2.60e-02	GO:0007127	meiosis I
1.64	3.33e-02	GO:0009889	regulation of biosynthetic process
12.30	4.72e-02	GO:0002377	immunoglobulin production

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
5.13	1.99e-16	GO:0005694	chromosome
1.82	5.59e-16	GO:0005634	nucleus
2.66	9.34e-16	GO:0044428	nuclear part
5.39	5.48e-15	GO:0044427	chromosomal part
3.23	6.11e-15	GO:0005654	nucleoplasm
2.79	7.72e-15	GO:0031981	nuclear lumen
2.43	1.22e-12	GO:0070013	intracellular organelle lumen
2.38	2.88e-12	GO:0031974	membrane-enclosed lumen
2.39	3.68e-12	GO:0043233	organelle lumen
1.45	8.18e-12	GO:0043231	intracellular membrane-bounded organelle
1.45	9.32e-12	GO:0043227	membrane-bounded organelle
1.69	2.62e-11	GO:0044446	intracellular organelle part
7.01	3.21e-11	GO:0000228	nuclear chromosome
20.75	3.32e-11	GO:0005657	replication fork
1.38	6.97e-11	GO:0043229	intracellular organelle
1.38	8.68e-11	GO:0043226	organelle
1.67	8.77e-11	GO:0044422	organelle part
7.15	3.05e-09	GO:0044454	nuclear chromosome part
5.84	1.24e-08	GO:0000785	chromatin
9.43	3.67e-08	GO:0032993	protein-DNA complex
1.24	1.74e-06	GO:0044424	intracellular part
20.36	4.79e-06	GO:0043596	nuclear replication fork
39.98	8.07e-06	GO:0042555	MCM complex
22.58	2.43e-05	GO:0030894	replisome
22.58	2.43e-05	GO:0043601	nuclear replisome
1.21	3.39e-05	GO:0005622	intracellular
1.77	8.73e-05	GO:0043228	non-membrane-bounded organelle
1.77	8.73e-05	GO:0043232	intracellular non-membrane-bounded organelle
2.65	3.96e-04	GO:0044451	nucleoplasm part
8.53	6.57e-04	GO:0000786	nucleosome
1.52	5.09e-03	GO:0032991	macromolecular complex
4.61	1.07e-02	GO:0000793	condensed chromosome
31.99	1.25e-02	GO:0005658	alpha DNA polymerase:primase complex
3.43	1.91e-02	GO:0005667	transcription factor complex
63.97	4.21e-02	GO:0032301	MutSalpha complex

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
2.24	5.25e-10	GO:0003677	DNA binding
1.88	2.55e-08	GO:0003676	nucleic acid binding
5.19	4.34e-05	GO:0043566	structure-specific DNA binding
10.10	4.69e-05	GO:0003697	single-stranded DNA binding
9.14	1.14e-04	GO:0008094	DNA-dependent ATPase activity
42.65	1.86e-04	GO:0032135	DNA insertion or deletion binding
36.56	4.30e-04	GO:0032404	mismatch repair complex binding
4.47	1.50e-03	GO:0003682	chromatin binding
47.98	3.30e-03	GO:0032138	single base insertion or deletion binding
47.98	3.30e-03	GO:0032405	MutLalpha complex binding
21.33	5.72e-03	GO:0000217	DNA secondary structure binding
4.74	1.08e-02	GO:0003690	double-stranded DNA binding
18.28	1.13e-02	GO:0030983	mismatched DNA binding
8.00	2.09e-02	GO:0003684	damaged DNA binding