Motif ID: EGR1..3.p2

Z-value: 2.302


Transcription factors associated with EGR1..3.p2:

Gene SymbolEntrez IDGene Name
EGR1 1958 early growth response 1
EGR2 1959 early growth response 2 (Krox-20 homolog, Drosophila)
EGR3 1960 early growth response 3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
EGR2hg19_v1_chr10_-_64578926_645789260.872.3e-03Click!
EGR3hg19_v1_chr8_-_22550057_22550092,
hg19_v1_chr8_-_22549901_22549901
0.853.4e-03Click!
EGR1hg19_v1_chr5_+_137801178_1378014500.742.3e-02Click!


Activity profile for motif EGR1..3.p2.

activity profile for motif EGR1..3.p2


Sorted Z-values histogram for motif EGR1..3.p2

Sorted Z-values for motif EGR1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EGR1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_38471170 4.997 NM_001243878
NM_004468
FHL3

four and a half LIM domains 3

chr7_-_100493481 4.371 NM_000665
NM_015831
ACHE

acetylcholinesterase

chr3_-_39195101 4.232 NM_033027
CSRNP1
cysteine-serine-rich nuclear protein 1
chr3_-_39195034 3.923 CSRNP1
cysteine-serine-rich nuclear protein 1
chr19_+_47778099 3.280 NM_178511
PRR24
proline rich 24
chr9_-_110251754 3.152 KLF4
Kruppel-like factor 4 (gut)
chr5_+_172483285 2.797 NM_001168393
NM_001168394
NM_153607
C5orf41


chromosome 5 open reading frame 41


chr9_-_86432546 2.650 NM_001135953
NM_025211
GKAP1

G kinase anchoring protein 1

chr13_-_110438896 2.511 NM_003749
IRS2
insulin receptor substrate 2
chr12_+_57482886 2.480 NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr6_-_109777171 2.359 NM_001159291
NM_022765
MICAL1

microtubule associated monoxygenase, calponin and LIM domain containing 1

chr9_-_110252045 2.330 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr8_+_16884745 2.322 NM_181723
EFHA2
EF-hand domain family, member A2
chr19_+_55795533 2.320 NM_032430
BRSK1
BR serine/threonine kinase 1
chr11_-_65667809 2.319 FOSL1
FOS-like antigen 1
chr8_-_8175860 2.292 SGK223
homolog of rat pragma of Rnd2
chr20_-_62258422 2.283 GMEB2
glucocorticoid modulatory element binding protein 2
chr6_-_109776946 2.280 MICAL1
microtubule associated monoxygenase, calponin and LIM domain containing 1
chr20_-_3388586 2.219 C20orf194
chromosome 20 open reading frame 194
chr19_+_13105970 2.212 NM_002501
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr9_-_110251308 2.208 KLF4
Kruppel-like factor 4 (gut)
chr2_+_28616360 2.207 FOSL2
FOS-like antigen 2
chr11_+_61447816 2.202 NM_006133
DAGLA
diacylglycerol lipase, alpha
chr22_+_38598065 2.179 MAFF
v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr5_+_137801178 2.176 NM_001964
EGR1
early growth response 1
chr12_+_57482674 2.151 NM_005967
NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr4_+_108745718 2.114 NM_001136258
SGMS2
sphingomyelin synthase 2
chr19_+_55795766 2.106 BRSK1
BR serine/threonine kinase 1
chrX_-_48814758 2.099 OTUD5
OTU domain containing 5
chr4_-_82393025 2.096 NM_152545
RASGEF1B
RasGEF domain family, member 1B
chrX_-_48814853 2.092 NM_001136157
NM_001136158
NM_017602
OTUD5


OTU domain containing 5


chr19_+_42788605 2.083 NM_015125
CIC
capicua homolog (Drosophila)
chr12_+_57482922 2.079 NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr16_-_66959418 2.072 NM_001128850
NM_004165
RRAD

Ras-related associated with diabetes

chr6_-_143266283 2.050 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr19_-_47734215 2.030 NM_014417
BBC3
BCL2 binding component 3
chr6_-_109776942 2.028 MICAL1
microtubule associated monoxygenase, calponin and LIM domain containing 1
chr22_-_20004251 2.021 NM_001670
ARVCF
armadillo repeat gene deleted in velocardiofacial syndrome
chr20_-_62258330 2.004 NM_012384
GMEB2
glucocorticoid modulatory element binding protein 2
chr19_+_45504686 1.995 NM_006509
RELB
v-rel reticuloendotheliosis viral oncogene homolog B
chr17_+_43299277 1.989 NM_005892
FMNL1
formin-like 1
chr22_+_50354428 1.977 PIM3
pim-3 oncogene
chr5_+_137801166 1.907 EGR1
early growth response 1
chr6_-_91006460 1.895 NM_021813
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr7_+_64498643 1.889 CCT6P3
chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr6_-_109777085 1.878 MICAL1
microtubule associated monoxygenase, calponin and LIM domain containing 1
chr19_-_1567875 1.840 NM_001174118
NM_203304
MEX3D

mex-3 homolog D (C. elegans)

chr7_-_32931409 1.809 NM_015483
KBTBD2
kelch repeat and BTB (POZ) domain containing 2
chr15_+_40733302 1.800 NM_014952
BAHD1
bromo adjacent homology domain containing 1
chr12_-_28122884 1.773 NM_198964
NM_198966
PTHLH

parathyroid hormone-like hormone

chr19_+_4969126 1.772 KDM4B
lysine (K)-specific demethylase 4B
chr10_-_77159851 1.756 ZNF503
zinc finger protein 503
chr16_+_1203240 1.748 NM_001005407
NM_021098
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr6_+_37137882 1.747 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr19_-_4065467 1.744 ZBTB7A
zinc finger and BTB domain containing 7A
chr14_-_21566497 1.712 ZNF219
zinc finger protein 219
chr10_-_77161136 1.692 ZNF503
zinc finger protein 503
chr4_-_82392971 1.691 RASGEF1B
RasGEF domain family, member 1B
chr2_+_28616346 1.682 FOSL2
FOS-like antigen 2
chr1_+_32827797 1.676 NM_052841
TSSK3
testis-specific serine kinase 3
chr22_-_50708720 1.667 NM_002751
MAPK11
mitogen-activated protein kinase 11
chr19_-_1863425 1.661 KLF16
Kruppel-like factor 16
chr19_+_4969123 1.651 NM_015015
KDM4B
lysine (K)-specific demethylase 4B
chr6_+_36164528 1.651 NM_015695
BRPF3
bromodomain and PHD finger containing, 3
chr20_-_3388219 1.643 NM_001009984
C20orf194
chromosome 20 open reading frame 194
chr11_-_65667860 1.636 NM_005438
FOSL1
FOS-like antigen 1
chr22_+_50354139 1.633 NM_001001852
PIM3
pim-3 oncogene
chr17_-_63557615 1.586 NM_004655
AXIN2
axin 2
chr8_-_103666018 1.585 NM_001032282
KLF10
Kruppel-like factor 10
chr22_+_21771661 1.572 NM_015094
HIC2
hypermethylated in cancer 2
chrX_-_48815088 1.546 OTUD5
OTU domain containing 5
chr1_-_16302272 1.545 NM_001242884
NM_003443
ZBTB17

zinc finger and BTB domain containing 17

chr19_-_1237840 1.537 NM_152769
C19orf26
chromosome 19 open reading frame 26
chr6_-_13711643 1.537 NM_005493
RANBP9
RAN binding protein 9
chr15_-_72410108 1.526 MYO9A
myosin IXA
chr19_-_460995 1.523 NM_012435
SHC2
SHC (Src homology 2 domain containing) transforming protein 2
chrX_+_153686620 1.521 NM_017514
PLXNA3
plexin A3
chr19_-_40931880 1.519 NM_013376
SERTAD1
SERTA domain containing 1
chr19_+_2476122 1.518 NM_015675
GADD45B
growth arrest and DNA-damage-inducible, beta
chr21_-_37528578 1.514 LOC100506428
uncharacterized LOC100506428
chrX_+_49126299 1.511 NM_001184745
NM_033215
PPP1R3F

protein phosphatase 1, regulatory subunit 3F

chr2_-_145274916 1.470 ZEB2
zinc finger E-box binding homeobox 2
chr1_-_1475739 1.469 NM_001114748
TMEM240
transmembrane protein 240
chr19_-_42759151 1.450 ERF
Ets2 repressor factor
chr11_+_45907198 1.441 MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr7_-_152132924 1.432 MLL3
myeloid/lymphoid or mixed-lineage leukemia 3
chr19_-_42759279 1.425 NM_006494
ERF
Ets2 repressor factor
chr15_-_72410226 1.414 NM_006901
MYO9A
myosin IXA
chr5_+_60628085 1.394 NM_020928
ZSWIM6
zinc finger, SWIM-type containing 6
chr15_-_61521416 1.391 RORA
RAR-related orphan receptor A
chr6_+_89791510 1.384 PNRC1
proline-rich nuclear receptor coactivator 1
chr10_+_104155431 1.367 NM_002502
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr7_-_32931363 1.362 KBTBD2
kelch repeat and BTB (POZ) domain containing 2
chr19_-_18392413 1.352 NM_005354
JUND
jun D proto-oncogene
chr19_-_18392436 1.351 JUND
jun D proto-oncogene
chr2_+_10183630 1.336 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr22_-_17602142 1.328 NM_031890
NM_001163079
CECR6

cat eye syndrome chromosome region, candidate 6

chr18_-_48724031 1.319 NM_016626
MEX3C
mex-3 homolog C (C. elegans)
chrX_-_135333519 1.304 NM_001173517
NM_024597
MAP7D3

MAP7 domain containing 3

chr6_+_19838612 1.300


chr10_+_98592015 1.272 NM_001170765
NM_001170766
LCOR

ligand dependent nuclear receptor corepressor

chr1_-_156470538 1.268 MEF2D
myocyte enhancer factor 2D
chr18_-_48723105 1.268 MEX3C
mex-3 homolog C (C. elegans)
chr16_-_3930685 1.258 CREBBP
CREB binding protein
chr5_+_56111379 1.255 MAP3K1
mitogen-activated protein kinase kinase kinase 1
chr14_-_21566728 1.255 NM_016423
ZNF219
zinc finger protein 219
chr2_+_241508103 1.252 RNPEPL1
arginyl aminopeptidase (aminopeptidase B)-like 1
chr2_+_42275017 1.249 NM_138370
PKDCC
protein kinase domain containing, cytoplasmic homolog (mouse)
chr1_+_212781969 1.246 NM_001040619
NM_001206484
NM_001206488
NM_001674
ATF3



activating transcription factor 3



chr19_-_15443307 1.240 BRD4
bromodomain containing 4
chrX_+_49126480 1.239 PPP1R3F
protein phosphatase 1, regulatory subunit 3F
chr9_+_139221931 1.239 NM_001145638
NM_015597
GPSM1

G-protein signaling modulator 1

chr15_-_60884615 1.239 NM_134262
RORA
RAR-related orphan receptor A
chr19_+_41305041 1.238 NM_080732
EGLN2
egl nine homolog 2 (C. elegans)
chr16_-_73092533 1.237 NM_001164766
ZFHX3
zinc finger homeobox 3
chr16_-_1020981 1.228 NM_022773
LMF1
lipase maturation factor 1
chr16_-_87417309 1.224 NM_024735
FBXO31
F-box protein 31
chr6_-_33266700 1.223 RGL2
ral guanine nucleotide dissociation stimulator-like 2
chr20_+_49348050 1.221 NM_032521
PARD6B
par-6 partitioning defective 6 homolog beta (C. elegans)
chr1_+_35331533 1.215


chr16_-_402617 1.214 NM_003502
NM_181050
AXIN1

axin 1

chr6_-_13711952 1.210 RANBP9
RAN binding protein 9
chr15_+_99191671 1.195 IGF1R
insulin-like growth factor 1 receptor
chr17_+_17584772 1.195 NM_030665
RAI1
retinoic acid induced 1
chrX_+_152953751 1.188 NM_001142805
NM_005629
SLC6A8

solute carrier family 6 (neurotransmitter transporter, creatine), member 8

chr11_+_66059364 1.180 NM_153266
TMEM151A
transmembrane protein 151A
chr2_+_149402321 1.180 EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr22_-_50221195 1.177 BRD1
bromodomain containing 1
chr1_+_212782103 1.172 ATF3
activating transcription factor 3
chr15_-_61521478 1.162 NM_134261
RORA
RAR-related orphan receptor A
chr3_+_50297644 1.153


chr11_-_1593149 1.146 NM_004420
DUSP8
dual specificity phosphatase 8
chr22_+_42229268 1.144 SREBF2
sterol regulatory element binding transcription factor 2
chr6_-_43423215 1.144 NM_023932
DLK2
delta-like 2 homolog (Drosophila)
chr19_+_8429010 1.143 NM_001039667
NM_139314
ANGPTL4

angiopoietin-like 4

chr10_-_77160650 1.138 ZNF503
zinc finger protein 503
chr5_+_56111352 1.136 MAP3K1
mitogen-activated protein kinase kinase kinase 1
chr22_+_24551944 1.135 CABIN1
calcineurin binding protein 1
chr22_+_51039178 1.131 MAPK8IP2
mitogen-activated protein kinase 8 interacting protein 2
chr4_+_186317964 1.130 ANKRD37
ankyrin repeat domain 37
chr19_+_7660698 1.128 NM_001080429
NM_020902
CAMSAP3

calmodulin regulated spectrin-associated protein family, member 3

chr2_+_220408742 1.125 NM_001005209
TMEM198
transmembrane protein 198
chr20_-_62462568 1.120 ZBTB46
zinc finger and BTB domain containing 46
chr14_+_105331581 1.120 NM_001112726
NM_015005
KIAA0284

KIAA0284

chr4_-_102267952 1.117 PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr19_+_45971249 1.112 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr2_+_220408352 1.110 TMEM198
transmembrane protein 198
chr3_+_183948216 1.106 NM_138345
VWA5B2
von Willebrand factor A domain containing 5B2
chr11_+_119076974 1.104 NM_005188
CBL
Cas-Br-M (murine) ecotropic retroviral transforming sequence
chr1_+_68150858 1.103 NM_001199741
NM_001199742
NM_001924
GADD45A


growth arrest and DNA-damage-inducible, alpha


chr14_+_105886253 1.103 MTA1
metastasis associated 1
chr11_+_66059335 1.099 TMEM151A
transmembrane protein 151A
chr6_+_138188352 1.096 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr16_+_1664640 1.095 NM_020825
CRAMP1L
Crm, cramped-like (Drosophila)
chr9_+_139971938 1.095 NM_207309
UAP1L1
UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr19_-_46272102 1.095


chr13_-_41635072 1.090 ELF1
E74-like factor 1 (ets domain transcription factor)
chr22_-_50964573 1.082 NM_001169110
SCO2
SCO cytochrome oxidase deficient homolog 2 (yeast)
chr14_+_105886146 1.081 NM_001203258
NM_004689
MTA1

metastasis associated 1

chr10_+_69644708 1.072 SIRT1
sirtuin 1
chr17_+_74261431 1.069 FAM100B
family with sequence similarity 100, member B
chr7_-_28220146 1.069 JAZF1
JAZF zinc finger 1
chr14_-_102553386 1.064 NM_005348
HSP90AA1
heat shock protein 90kDa alpha (cytosolic), class A member 1
chr20_+_44034632 1.063 NM_001197139
NM_001048221
NM_001048222
NM_001197140
NM_018478
DBNDD2




dysbindin (dystrobrevin binding protein 1) domain containing 2




chr6_-_11232883 1.063 NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr16_+_69600110 1.062 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr7_-_152133071 1.060 NM_170606
MLL3
myeloid/lymphoid or mixed-lineage leukemia 3
chr19_+_10400646 1.058 NM_003259
ICAM5
intercellular adhesion molecule 5, telencephalin
chr6_+_126070813 1.057 HEY2
hairy/enhancer-of-split related with YRPW motif 2
chr16_-_3930120 1.055 NM_001079846
NM_004380
CREBBP

CREB binding protein

chr19_+_36208917 1.054 NM_014727
MLL4
myeloid/lymphoid or mixed-lineage leukemia 4
chr19_-_1863546 1.052 NM_031918
KLF16
Kruppel-like factor 16
chr22_+_51039100 1.051 NM_012324
MAPK8IP2
mitogen-activated protein kinase 8 interacting protein 2
chr19_-_15443133 1.050 BRD4
bromodomain containing 4
chr7_-_32931189 1.043 KBTBD2
kelch repeat and BTB (POZ) domain containing 2
chr22_+_42229137 1.040 SREBF2
sterol regulatory element binding transcription factor 2
chr12_-_51611476 1.035 POU6F1
POU class 6 homeobox 1
chr7_-_140624280 1.035 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr11_-_33722285 1.029 NM_001166692
C11orf91
chromosome 11 open reading frame 91
chr12_+_52445185 1.019 NM_002135
NM_173157
NR4A1

nuclear receptor subfamily 4, group A, member 1

chr5_+_179248089 1.017 SQSTM1
sequestosome 1
chr11_+_64073040 1.014 NM_004451
ESRRA
estrogen-related receptor alpha
chr5_+_179247903 1.013 SQSTM1
sequestosome 1
chr1_+_236305831 1.012 NM_003272
GPR137B
G protein-coupled receptor 137B
chr7_+_28530747 1.010 CREB5
cAMP responsive element binding protein 5
chr14_-_71275732 1.007 NM_033141
MAP3K9
mitogen-activated protein kinase kinase kinase 9
chrX_+_49126326 1.006 PPP1R3F
protein phosphatase 1, regulatory subunit 3F
chr19_+_41305100 1.005 EGLN2
egl nine homolog 2 (C. elegans)
chr6_-_36164973 1.003


chr1_-_51425795 1.000 FAF1
Fas (TNFRSF6) associated factor 1
chr5_+_179247841 0.995 NM_003900
SQSTM1
sequestosome 1
chr19_+_41305333 0.995 NM_053046
EGLN2
egl nine homolog 2 (C. elegans)
chr19_+_16683360 0.994


chr19_+_36209125 0.994 MLL4
myeloid/lymphoid or mixed-lineage leukemia 4
chr1_-_51425740 0.994 FAF1
Fas (TNFRSF6) associated factor 1
chr19_-_46000159 0.992 NM_005619
NM_206900
RTN2

reticulon 2

chr5_+_14143287 0.991 NM_007118
TRIO
triple functional domain (PTPRF interacting)
chr19_+_35491329 0.988 GRAMD1A
GRAM domain containing 1A
chr2_+_171572698 0.983 SP5
Sp5 transcription factor
chr4_-_54930466 0.983 CHIC2
cysteine-rich hydrophobic domain 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.81 3.02e-14 GO:0060255 regulation of macromolecule metabolic process
3.40 4.94e-14 GO:0051252 regulation of RNA metabolic process
3.46 5.02e-14 GO:0006355 regulation of transcription, DNA-dependent
3.24 1.70e-13 GO:2000112 regulation of cellular macromolecule biosynthetic process
3.16 5.38e-13 GO:0010556 regulation of macromolecule biosynthetic process
2.63 9.05e-13 GO:0031323 regulation of cellular metabolic process
2.50 1.70e-12 GO:0019222 regulation of metabolic process
2.63 1.97e-12 GO:0080090 regulation of primary metabolic process
2.99 2.75e-12 GO:0031326 regulation of cellular biosynthetic process
2.96 4.48e-12 GO:0009889 regulation of biosynthetic process
3.01 8.93e-12 GO:0010468 regulation of gene expression
2.90 1.01e-11 GO:0051171 regulation of nitrogen compound metabolic process
2.94 1.24e-11 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.86 8.18e-11 GO:0050794 regulation of cellular process
1.79 2.93e-10 GO:0050789 regulation of biological process
1.72 1.88e-09 GO:0065007 biological regulation
4.14 6.95e-08 GO:0006357 regulation of transcription from RNA polymerase II promoter
4.28 1.77e-07 GO:0006351 transcription, DNA-dependent
3.86 1.59e-06 GO:0032774 RNA biosynthetic process
2.42 3.45e-06 GO:0048518 positive regulation of biological process
3.22 1.92e-05 GO:0009893 positive regulation of metabolic process
3.26 5.28e-05 GO:0010604 positive regulation of macromolecule metabolic process
2.38 5.29e-05 GO:0048522 positive regulation of cellular process
2.34 2.02e-04 GO:0048519 negative regulation of biological process
3.69 2.94e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
3.04 3.51e-04 GO:0031325 positive regulation of cellular metabolic process
2.36 5.60e-04 GO:0048523 negative regulation of cellular process
3.62 8.08e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.44 8.73e-04 GO:0031328 positive regulation of cellular biosynthetic process
3.39 1.13e-03 GO:0009891 positive regulation of biosynthetic process
4.38 1.18e-03 GO:0043549 regulation of kinase activity
4.23 1.83e-03 GO:0051338 regulation of transferase activity
1.77 2.39e-03 GO:0044260 cellular macromolecule metabolic process
3.49 2.64e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
3.63 2.92e-03 GO:0010628 positive regulation of gene expression
2.44 3.51e-03 GO:0016070 RNA metabolic process
4.26 3.69e-03 GO:0045859 regulation of protein kinase activity
2.37 4.22e-03 GO:0010467 gene expression
1.69 4.22e-03 GO:0043170 macromolecule metabolic process
3.71 4.47e-03 GO:0045893 positive regulation of transcription, DNA-dependent
2.44 5.02e-03 GO:0034645 cellular macromolecule biosynthetic process
2.41 6.29e-03 GO:0009059 macromolecule biosynthetic process
1.80 1.02e-02 GO:0032502 developmental process
3.45 1.07e-02 GO:0051254 positive regulation of RNA metabolic process
3.01 1.12e-02 GO:0050793 regulation of developmental process
3.42 1.21e-02 GO:0042325 regulation of phosphorylation
2.69 1.33e-02 GO:0050790 regulation of catalytic activity
2.48 1.33e-02 GO:0065009 regulation of molecular function
6.89 1.48e-02 GO:0080135 regulation of cellular response to stress
3.76 1.51e-02 GO:0045892 negative regulation of transcription, DNA-dependent
1.84 1.65e-02 GO:0007165 signal transduction
3.32 1.73e-02 GO:0019220 regulation of phosphate metabolic process
3.32 1.73e-02 GO:0051174 regulation of phosphorus metabolic process
22.60 1.80e-02 GO:0060350 endochondral bone morphogenesis
3.68 1.89e-02 GO:0051253 negative regulation of RNA metabolic process
2.11 2.04e-02 GO:0090304 nucleic acid metabolic process
3.41 2.31e-02 GO:0001932 regulation of protein phosphorylation
1.72 2.32e-02 GO:0051716 cellular response to stimulus
3.08 2.50e-02 GO:0031399 regulation of protein modification process
4.93 2.55e-02 GO:0071900 regulation of protein serine/threonine kinase activity
1.81 2.56e-02 GO:0007275 multicellular organismal development
1.75 3.74e-02 GO:0023052 signaling
7.17 3.83e-02 GO:0001503 ossification
3.92 3.95e-02 GO:0032583 regulation of gene-specific transcription
11.82 4.33e-02 GO:0043506 regulation of JUN kinase activity
35.43 4.77e-02 GO:0002076 osteoblast development

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.99 9.97e-11 GO:0005634 nucleus
1.33 2.30e-03 GO:0043229 intracellular organelle
1.33 2.53e-03 GO:0043226 organelle
1.37 2.78e-03 GO:0043231 intracellular membrane-bounded organelle
1.37 2.92e-03 GO:0043227 membrane-bounded organelle

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
5.18 5.16e-15 GO:0001071 nucleic acid binding transcription factor activity
5.18 5.16e-15 GO:0003700 sequence-specific DNA binding transcription factor activity
2.63 8.12e-08 GO:0003677 DNA binding
4.45 5.50e-07 GO:0043565 sequence-specific DNA binding
2.58 3.30e-06 GO:0008270 zinc ion binding
2.45 3.37e-06 GO:0046914 transition metal ion binding
2.10 7.46e-06 GO:0003676 nucleic acid binding
1.81 6.37e-04 GO:0046872 metal ion binding
77.95 6.51e-04 GO:0031434 mitogen-activated protein kinase kinase binding
1.79 8.90e-04 GO:0043169 cation binding
1.79 9.57e-04 GO:0043167 ion binding
2.87 1.72e-03 GO:0030528 transcription regulator activity
5.05 1.14e-02 GO:0019900 kinase binding
5.26 2.18e-02 GO:0019901 protein kinase binding