Motif ID: FOXD3.p2

Z-value: 1.098


Transcription factors associated with FOXD3.p2:

Gene SymbolEntrez IDGene Name
FOXD3 27022 forkhead box D3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOXD3hg19_v1_chr1_+_63788729_637887290.304.4e-01Click!


Activity profile for motif FOXD3.p2.

activity profile for motif FOXD3.p2


Sorted Z-values histogram for motif FOXD3.p2

Sorted Z-values for motif FOXD3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXD3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_30130982 2.107 NM_033229
TRIM15
tripartite motif containing 15
chr8_-_6420454 1.236 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr6_+_26501448 1.148 NM_001732
BTN1A1
butyrophilin, subfamily 1, member A1
chr22_-_43036606 1.000 NM_001165877
ATP5L2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit G2
chr3_+_136676706 0.978 NM_144717
IL20RB
interleukin 20 receptor beta
chr11_-_790103 0.964 NM_016564
CEND1
cell cycle exit and neuronal differentiation 1
chrX_-_76937157 0.915 ATRX
alpha thalassemia/mental retardation syndrome X-linked
chr2_-_158182154 0.914 NM_020711
ERMN
ermin, ERM-like protein
chr4_+_71062241 0.861 NM_017855
ODAM
odontogenic, ameloblast asssociated
chr7_+_28475233 0.840 NM_004904
CREB5
cAMP responsive element binding protein 5
chr11_-_5537815 0.745 NM_145053
UBQLNL
ubiquilin-like
chr7_+_23530136 0.698 RPS2P32
ribosomal protein S2 pseudogene 32
chr16_-_28437663 0.669 NM_001199142
EIF3C
eukaryotic translation initiation factor 3, subunit C
chr13_+_21183940 0.656


chr12_+_49297892 0.652 NM_033124
CCDC65
coiled-coil domain containing 65
chr4_+_108814419 0.619 NM_001136257
NM_152621
SGMS2

sphingomyelin synthase 2

chr15_+_32933869 0.610 NM_001144757
NM_003020
SCG5

secretogranin V (7B2 protein)

chr3_+_132316080 0.602 NM_016557
CCRL1
chemokine (C-C motif) receptor-like 1
chr7_+_129906702 0.586 NM_001869
CPA2
carboxypeptidase A2 (pancreatic)
chr2_+_166095911 0.584 NM_001040142
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr7_+_28725597 0.580 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr12_+_21284127 0.579 NM_006446
SLCO1B1
solute carrier organic anion transporter family, member 1B1
chrX_-_76814217 0.578 ATRX
alpha thalassemia/mental retardation syndrome X-linked
chr19_+_13134782 0.571 NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr11_+_63304272 0.569 NM_004585
RARRES3
retinoic acid receptor responder (tazarotene induced) 3
chr12_-_8088629 0.557 NM_006931
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr10_+_18689512 0.554 NM_201570
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr3_-_15382874 0.539 NM_001018009
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr4_-_90759446 0.521 NM_001146055
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr7_-_16505292 0.513 NM_015464
SOSTDC1
sclerostin domain containing 1
chr3_-_42814734 0.507 NM_144719
CCDC13
coiled-coil domain containing 13
chr10_-_94003002 0.491 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr1_+_84764048 0.490 NM_001010971
SAMD13
sterile alpha motif domain containing 13
chr5_+_173472692 0.474 NM_015980
HMP19
HMP19 protein
chr7_+_28452143 0.473 NM_182898
CREB5
cAMP responsive element binding protein 5
chr7_+_28530747 0.463 CREB5
cAMP responsive element binding protein 5
chr5_+_71502700 0.457 MAP1B
microtubule-associated protein 1B
chr3_+_122296432 0.456 NM_001113523
PARP15
poly (ADP-ribose) polymerase family, member 15
chrM_+_10123 0.450


chr11_-_63330854 0.437 NM_017878
HRASLS2
HRAS-like suppressor 2
chr19_-_4831711 0.430 NM_182919
TICAM1
toll-like receptor adaptor molecule 1
chr4_+_75174189 0.419 NM_001013442
EPGN
epithelial mitogen homolog (mouse)
chr4_-_186392847 0.411 NM_001145411
NM_152775
CCDC110

coiled-coil domain containing 110

chr5_+_159436143 0.409 TTC1
tetratricopeptide repeat domain 1
chr12_+_56915587 0.403 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr19_+_49375677 0.396 PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr16_+_81812897 0.395 NM_002661
PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr12_+_101988746 0.394 NM_002465
NM_206819
NM_206820
NM_206821
MYBPC1



myosin binding protein C, slow type



chr8_-_87755880 0.390 NM_019098
CNGB3
cyclic nucleotide gated channel beta 3
chr16_+_81812899 0.387 PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr11_+_5775922 0.381 NM_001005175
OR52N4
olfactory receptor, family 52, subfamily N, member 4
chr11_-_125550674 0.370 NM_001612
NM_020069
NM_020107
NM_020108
ACRV1



acrosomal vesicle protein 1



chr15_+_78558522 0.361 NM_001130183
DNAJA4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr9_-_4299915 0.360 GLIS3
GLIS family zinc finger 3
chr19_-_47735858 0.360 NM_001127240
NM_001127241
NM_001127242
BBC3


BCL2 binding component 3


chr21_+_33664123 0.359 NM_178817
NM_206898
MRAP

melanocortin 2 receptor accessory protein

chr5_+_140613937 0.358 PCDHB18
protocadherin beta 18 pseudogene
chr2_+_241544819 0.358 NM_001195381
NM_001195382
GPR35

G protein-coupled receptor 35

chr18_-_47814691 0.358 NM_001101654
NM_014593
CXXC1

CXXC finger protein 1

chr2_-_183387063 0.357 NM_005019
NM_001003683
PDE1A

phosphodiesterase 1A, calmodulin-dependent

chr5_+_108083522 0.355 NM_005246
FER
fer (fps/fes related) tyrosine kinase
chr21_+_35736322 0.355 NM_172201
KCNE2
potassium voltage-gated channel, Isk-related family, member 2
chr14_+_102276125 0.354 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr3_-_101039403 0.353 NM_016247
IMPG2
interphotoreceptor matrix proteoglycan 2
chr7_-_87342569 0.351 NM_000927
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr20_+_55099784 0.350 NM_001012971
FAM209A
FAM209B
family with sequence similarity 209, member A
family with sequence similarity 209, member B
chr2_+_143635225 0.346 KYNU
kynureninase
chr11_-_78052925 0.345 NM_012296
GAB2
GRB2-associated binding protein 2
chr19_-_45996470 0.344 NM_206901
RTN2
reticulon 2
chr19_-_10679328 0.344 CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr3_+_46448678 0.337 NM_003965
NM_001130910
CCRL2

chemokine (C-C motif) receptor-like 2

chr7_+_123249076 0.333 NM_080928
ASB15
ankyrin repeat and SOCS box containing 15
chr2_+_210444154 0.332 MAP2
microtubule-associated protein 2
chr3_-_105421044 0.332 CBLB
Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr19_-_55836668 0.330 NM_001085488
TMEM150B
transmembrane protein 150B
chr3_-_10334600 0.330 NM_001134944
NM_001134945
NM_001134946
GHRL


ghrelin/obestatin prepropeptide


chr1_+_212788359 0.325 NM_001206486
ATF3
activating transcription factor 3
chr15_-_41166336 0.325 NM_133639
RHOV
ras homolog gene family, member V
chr1_-_244006471 0.323 NM_005465
NM_181690
AKT3

v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

chr17_-_7531107 0.320 NM_133491
SAT2
spermidine/spermine N1-acetyltransferase family member 2
chr5_+_40841296 0.318 NM_032587
CARD6
caspase recruitment domain family, member 6
chr2_-_161056762 0.316 ITGB6
integrin, beta 6
chr10_+_96522457 0.316 NM_000769
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr12_+_27175482 0.315 NM_004264
MED21
mediator complex subunit 21
chr3_-_15563160 0.315 NM_005677
NM_080539
COLQ

collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase

chr4_-_153303663 0.314 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chrX_-_44202834 0.309 NM_025184
EFHC2
EF-hand domain (C-terminal) containing 2
chr5_+_159436155 0.309 NM_003314
TTC1
tetratricopeptide repeat domain 1
chr15_-_60919642 0.307 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chr12_-_10251520 0.306 NM_016511
CLEC1A
C-type lectin domain family 1, member A
chr1_+_241695433 0.301 NM_003679
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr15_+_93443559 0.295 CHD2
chromodomain helicase DNA binding protein 2
chr19_+_48964505 0.295 NM_170720
KCNJ14
potassium inwardly-rectifying channel, subfamily J, member 14
chr4_+_71494460 0.294 NM_031889
ENAM
enamelin
chrX_-_64196268 0.294 NM_001178033
NM_018684
ZC4H2

zinc finger, C4H2 domain containing

chr4_+_41983712 0.294 NM_001029955
DCAF4L1
DDB1 and CUL4 associated factor 4-like 1
chr12_+_47610051 0.294 NM_138371
FAM113B
family with sequence similarity 113, member B
chr21_-_27512668 0.290 NM_001136016
APP
amyloid beta (A4) precursor protein
chr12_-_371994 0.288 NM_001190997
NM_001243392
NM_016615
SLC6A13


solute carrier family 6 (neurotransmitter transporter, GABA), member 13


chr12_-_11091805 0.288 NM_023922
TAS2R14
taste receptor, type 2, member 14
chr16_-_279338 0.288 NM_018032
NM_201412
LUC7L

LUC7-like (S. cerevisiae)

chr2_+_169643048 0.287 NM_001171631
NOSTRIN
nitric oxide synthase trafficker
chr5_+_173472737 0.285 HMP19
HMP19 protein
chr15_+_93443418 0.284 NM_001042572
NM_001271
CHD2

chromodomain helicase DNA binding protein 2

chr12_-_10588543 0.281 NM_002260
KLRC2
KLRC3
killer cell lectin-like receptor subfamily C, member 2
killer cell lectin-like receptor subfamily C, member 3
chr12_-_10978867 0.278 NM_023921
TAS2R10
taste receptor, type 2, member 10
chr6_-_26108320 0.278 NM_005323
HIST1H1T
histone cluster 1, H1t
chr15_-_77176191 0.277 NM_020843
SCAPER
S-phase cyclin A-associated protein in the ER
chr14_+_32798478 0.277 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr18_+_616671 0.276 NM_199167
CLUL1
clusterin-like 1 (retinal)
chr21_-_43735705 0.275 NM_003226
TFF3
trefoil factor 3 (intestinal)
chr20_+_1184097 0.275 NM_001009612
C20orf202
chromosome 20 open reading frame 202
chr9_+_74920329 0.273


chr21_-_33957746 0.272 NM_144659
TCP10L
t-complex 10 (mouse)-like
chr1_+_192286121 0.269 NM_001039152
RGS21
regulator of G-protein signaling 21
chr8_+_54764367 0.268 NM_170587
RGS20
regulator of G-protein signaling 20
chr12_-_10542616 0.267 NM_007360
KLRK1
killer cell lectin-like receptor subfamily K, member 1
chr7_+_139528951 0.266 NM_001061
NM_001166253
NM_030984
TBXAS1


thromboxane A synthase 1 (platelet)


chr4_+_186350543 0.265 NM_001114357
C4orf47
chromosome 4 open reading frame 47
chr1_-_162346579 0.264 NM_182581
C1orf111
chromosome 1 open reading frame 111
chr14_-_81864726 0.260 NM_033104
STON2
stonin 2
chr14_-_74025643 0.258 NM_001220484
NM_203309
HEATR4

HEAT repeat containing 4

chr2_-_170430312 0.258 NM_024622
FASTKD1
FAST kinase domains 1
chr11_+_5474637 0.256 NM_001004754
OR51I2
olfactory receptor, family 51, subfamily I, member 2
chr12_+_21679190 0.253 NM_030572
C12orf39
chromosome 12 open reading frame 39
chr3_-_126327397 0.251 NM_001039783
TXNRD3NB
thioredoxin reductase 3 neighbor
chr17_-_37322413 0.249 NM_001143968
ARL5C
ADP-ribosylation factor-like 5C
chr2_+_88047603 0.247 NM_002665
NM_001032392
PLGLB2
PLGLB1
plasminogen-like B2
plasminogen-like B1
chr19_-_11689765 0.247 NM_001111035
NM_001111036
ACP5

acid phosphatase 5, tartrate resistant

chr13_-_41593491 0.244 NM_172373
ELF1
E74-like factor 1 (ets domain transcription factor)
chr4_+_187148624 0.244 NM_000892
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr9_-_99775855 0.244 HIATL2
hippocampus abundant transcript-like 2
chr19_+_49375679 0.243 PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr9_+_103340335 0.242 NM_001018116
MURC
muscle-related coiled-coil protein
chr20_+_51589752 0.242 TSHZ2
teashirt zinc finger homeobox 2
chr12_+_105153258 0.241 CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr3_+_171561138 0.241 NM_001164436
TMEM212
transmembrane protein 212
chr11_-_5526833 0.240 NM_001005567
OR51B5
HBE1
olfactory receptor, family 51, subfamily B, member 5
hemoglobin, epsilon 1
chr7_+_128312345 0.240 NM_001012454
NM_001128926
FAM71F2

family with sequence similarity 71, member F2

chr8_-_95274520 0.239 GEM
GTP binding protein overexpressed in skeletal muscle
chr19_+_49375638 0.239 NM_014330
PPP1R15A
protein phosphatase 1, regulatory subunit 15A
chr7_+_116395440 0.238


chr2_-_158184145 0.238 NM_001009959
ERMN
ermin, ERM-like protein
chr11_-_5863126 0.238 NM_001005167
OR52E6
olfactory receptor, family 52, subfamily E, member 6
chr17_+_7531275 0.236 SHBG
sex hormone-binding globulin
chr13_-_33859835 0.234 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr6_-_52668599 0.233 NM_145740
GSTA1
glutathione S-transferase alpha 1
chr19_+_18118921 0.231 NM_015683
ARRDC2
arrestin domain containing 2
chr19_+_11485360 0.230 NM_175871
SWSAP1
SWIM-type zinc finger 7 associated protein 1
chr4_-_186456580 0.230 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chr12_+_123319293 0.229 HIP1R
huntingtin interacting protein 1 related
chr5_-_64777703 0.227 NM_197941
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr21_+_46293925 0.226


chr8_+_87111132 0.225 NM_152565
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr17_-_34195745 0.223 NM_152781
C17orf66
chromosome 17 open reading frame 66
chr17_-_6983503 0.222 NM_006344
NM_182906
CLEC10A

C-type lectin domain family 10, member A

chrX_-_24045302 0.221 NM_030624
KLHL15
kelch-like 15 (Drosophila)
chr19_+_11200037 0.220 NM_000527
NM_001195798
NM_001195799
NM_001195800
NM_001195802
NM_001195803
LDLR





low density lipoprotein receptor





chr4_+_187187342 0.220 F11
coagulation factor XI
chr7_+_112120907 0.218 NM_001134468
NM_182597
C7orf53

chromosome 7 open reading frame 53

chr6_-_87804773 0.215 NM_000735
NM_001252383
CGA

glycoprotein hormones, alpha polypeptide

chr11_-_128894008 0.214 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr6_-_27858569 0.214 NM_003535
HIST1H3J
histone cluster 1, H3j
chr19_-_36499583 0.214 NM_001039876
C19orf46
chromosome 19 open reading frame 46
chr11_-_17191287 0.214 NM_002645
PIK3C2A
phosphoinositide-3-kinase, class 2, alpha polypeptide
chr15_+_42696957 0.211 NM_173089
NM_173090
CAPN3

calpain 3, (p94)

chr13_+_41635622 0.210 NM_007187
WBP4
WW domain binding protein 4 (formin binding protein 21)
chr6_-_31514620 0.209 NM_001204078
NM_130463
NM_138282
ATP6V1G2


ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2


chrX_+_9935397 0.208 NM_001195081
LOC100288814
uncharacterized LOC100288814
chr15_+_66874506 0.208


chr7_-_120498128 0.208 NM_012338
TSPAN12
tetraspanin 12
chr20_+_2276612 0.206 NM_003245
TGM3
transglutaminase 3 (E polypeptide, protein-glutamine-gamma-glutamyltransferase)
chr15_+_71839540 0.205 THSD4
thrombospondin, type I, domain containing 4
chr10_-_31288420 0.203 NM_001143769
ZNF438
zinc finger protein 438
chr5_+_140529619 0.202 NM_018939
PCDHB6
protocadherin beta 6
chr9_+_6720862 0.202 NM_001146696
KDM4C
lysine (K)-specific demethylase 4C
chr19_+_17392453 0.202 NM_152363
ANKLE1
ankyrin repeat and LEM domain containing 1
chr20_+_43990576 0.202 NM_001197129
SYS1
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr7_+_134576187 0.202 CALD1
caldesmon 1
chr2_+_169659099 0.200 NM_001039724
NM_001171632
NM_052946
NOSTRIN


nitric oxide synthase trafficker


chrX_-_8769377 0.200 NM_001171186
NM_174951
FAM9A

family with sequence similarity 9, member A

chr16_+_4382224 0.200 NM_032575
GLIS2
GLIS family zinc finger 2
chr1_-_151813032 0.199 NM_001136003
C2CD4D
C2 calcium-dependent domain containing 4D
chr11_+_109963524 0.199 ZC3H12C
zinc finger CCCH-type containing 12C
chrX_-_48327739 0.197 SLC38A5
solute carrier family 38, member 5
chr3_-_114343052 0.197 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr12_-_18243052 0.196 NM_024730
RERGL
RERG/RAS-like
chr1_-_16399936 0.195 NM_182623
FAM131C
family with sequence similarity 131, member C
chr9_-_117267710 0.194 NM_001173425
NM_015404
DFNB31

deafness, autosomal recessive 31

chrX_+_123234462 0.193 STAG2
stromal antigen 2
chr2_-_161056573 0.193 NM_000888
ITGB6
integrin, beta 6
chr9_+_131683173 0.190 NM_001100876
NM_174933
PHYHD1

phytanoyl-CoA dioxygenase domain containing 1

chr2_+_210444364 0.190 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr6_+_27925018 0.190 NM_012367
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr15_+_59908908 0.190 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr19_-_13617037 0.190 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr5_+_147582338 0.189 NM_001195290
NM_205841
SPINK6

serine peptidase inhibitor, Kazal type 6

chr19_+_46498338 0.188 NM_001080402
CCDC61
coiled-coil domain containing 61
chr4_-_184241926 0.188 NM_001111319
CLDN22
claudin 22
chr3_-_112693711 0.187 NM_138806
NM_138939
NM_138940
NM_170780
CD200R1



CD200 receptor 1




Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.