Motif ID: HMGA1,2.p2

Z-value: 1.266


Transcription factors associated with HMGA1,2.p2:

Gene SymbolEntrez IDGene Name
HMGA1 3159 high mobility group AT-hook 1
HMGA2 8091 high mobility group AT-hook 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HMGA1hg19_v1_chr6_+_34204576_34204646-0.422.5e-01Click!
HMGA2hg19_v1_chr12_+_66218879_66219147-0.186.5e-01Click!


Activity profile for motif HMGA1,2.p2.

activity profile for motif HMGA1,2.p2


Sorted Z-values histogram for motif HMGA1,2.p2

Sorted Z-values for motif HMGA1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HMGA1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_6420454 0.940 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr2_-_188312872 0.891 NM_005795
CALCRL
calcitonin receptor-like
chr6_-_87804773 0.889 NM_000735
NM_001252383
CGA

glycoprotein hormones, alpha polypeptide

chr14_-_73453651 0.846 NM_178441
ZFYVE1
zinc finger, FYVE domain containing 1
chr12_+_21679190 0.841 NM_030572
C12orf39
chromosome 12 open reading frame 39
chr11_-_104972147 0.793 NM_001007232
NM_001223
NM_033292
NM_033293
NM_033294
NM_033295
CARD17
CASP1




caspase recruitment domain family, member 17
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)




chr8_+_87111132 0.767 NM_152565
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr2_-_158182154 0.766 NM_020711
ERMN
ermin, ERM-like protein
chr6_+_132873829 0.744 NM_053278
TAAR8
trace amine associated receptor 8
chr4_+_88896801 0.732 NM_000582
NM_001040058
NM_001040060
NM_001251829
NM_001251830
SPP1




secreted phosphoprotein 1




chr4_+_88896838 0.711 SPP1
secreted phosphoprotein 1
chr7_-_41742666 0.695 NM_002192
INHBA
inhibin, beta A
chr11_-_85469043 0.680 NM_001162951
NM_001162953
SYTL2

synaptotagmin-like 2

chr4_+_88896868 0.678 SPP1
secreted phosphoprotein 1
chr1_-_161337663 0.667 NM_001013625
C1orf192
chromosome 1 open reading frame 192
chr16_-_90096308 0.650 NM_001214
C16orf3
chromosome 16 open reading frame 3
chr7_+_141490016 0.626 NM_018980
TAS2R5
taste receptor, type 2, member 5
chr3_-_167191808 0.621 NM_006217
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr11_+_56756346 0.621 NM_001005323
OR5AK2
olfactory receptor, family 5, subfamily AK, member 2
chr14_-_57960432 0.619 NM_018168
C14orf105
chromosome 14 open reading frame 105
chr2_+_210444154 0.618 MAP2
microtubule-associated protein 2
chr11_-_18062304 0.618 NM_004179
TPH1
tryptophan hydroxylase 1
chr11_-_76998462 0.580 NM_182833
GDPD4
glycerophosphodiester phosphodiesterase domain containing 4
chr2_-_175462428 0.575 WIPF1
WAS/WASL interacting protein family, member 1
chr5_+_147582338 0.561 NM_001195290
NM_205841
SPINK6

serine peptidase inhibitor, Kazal type 6

chr5_-_172083569 0.549


chr19_-_46526555 0.545 NM_005091
PGLYRP1
peptidoglycan recognition protein 1
chr1_-_183559463 0.541 NCF2
neutrophil cytosolic factor 2
chr2_-_158184145 0.533 NM_001009959
ERMN
ermin, ERM-like protein
chr19_+_49109999 0.532 NM_133498
SPACA4
sperm acrosome associated 4
chr1_+_196857143 0.532 NM_001201550
NM_001201551
NM_006684
CFHR4


complement factor H-related 4


chr1_+_212475147 0.529 NM_001199756
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr19_+_48964505 0.525 NM_170720
KCNJ14
potassium inwardly-rectifying channel, subfamily J, member 14
chr2_-_198540583 0.523 NM_144629
RFTN2
raftlin family member 2
chr6_+_149721494 0.517 NM_001002255
SUMO4
SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae)
chr9_+_75766794 0.511 ANXA1
annexin A1
chr10_+_5238756 0.500 NM_001818
AKR1C4
aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)
chrX_+_65384078 0.499 NM_001130860
NM_014799
HEPH

hephaestin

chr1_-_183559669 0.493 NM_000433
NM_001190789
NM_001190794
NCF2


neutrophil cytosolic factor 2


chrX_-_76937157 0.484 ATRX
alpha thalassemia/mental retardation syndrome X-linked
chr10_-_118680978 0.477 KIAA1598
KIAA1598
chr12_+_80603232 0.475 NM_173591
OTOGL
otogelin-like
chr6_-_64029847 0.467 NM_001143940
NM_016571
LGSN

lengsin, lens protein with glutamine synthetase domain

chr16_+_53479685 0.458 RBL2
retinoblastoma-like 2 (p130)
chr1_+_186798031 0.457 NM_024420
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chrM_+_10123 0.455


chr7_-_115670774 0.449 TFEC
transcription factor EC
chr2_-_87248942 0.447 NM_002665
NM_001032392
PLGLB2
PLGLB1
plasminogen-like B2
plasminogen-like B1
chr10_-_5045967 0.446 NM_001135241
AKR1C2
aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chr11_-_6817013 0.441 NM_003696
OR6A2
olfactory receptor, family 6, subfamily A, member 2
chr6_+_127898318 0.437 NM_001010905
C6orf58
chromosome 6 open reading frame 58
chr19_-_16250695 0.431


chr9_+_75766777 0.425 NM_000700
ANXA1
annexin A1
chrX_-_23855456 0.423 RPL9
ribosomal protein L9
chr19_-_44384240 0.420 NM_001033719
ZNF404
zinc finger protein 404
chr5_+_40909558 0.412 NM_000587
C7
complement component 7
chr2_+_88047603 0.411 NM_002665
NM_001032392
PLGLB2
PLGLB1
plasminogen-like B2
plasminogen-like B1
chr3_-_112693711 0.411 NM_138806
NM_138939
NM_138940
NM_170780
CD200R1



CD200 receptor 1



chr1_-_244006471 0.408 NM_005465
NM_181690
AKT3

v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

chr12_-_87232635 0.405 NM_013244
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr15_+_59908908 0.403 GCNT3
glucosaminyl (N-acetyl) transferase 3, mucin type
chr5_+_71502700 0.398 MAP1B
microtubule-associated protein 1B
chr2_-_158300517 0.395 NM_004288
CYTIP
cytohesin 1 interacting protein
chr2_-_178787522 0.389 NM_001077358
PDE11A
phosphodiesterase 11A
chr1_+_171283372 0.387 NM_002022
FMO4
flavin containing monooxygenase 4
chr3_+_38307297 0.380 NM_004256
SLC22A13
solute carrier family 22 (organic anion transporter), member 13
chr8_+_62200524 0.378 NM_173519
CLVS1
clavesin 1
chr4_-_139163222 0.375 NM_014331
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr1_+_156030965 0.373 NM_020387
RAB25
RAB25, member RAS oncogene family
chr19_+_37342552 0.370 NM_001242475
NM_001242476
ZNF345

zinc finger protein 345

chr6_+_139349818 0.369 NM_021243
C6orf115
chromosome 6 open reading frame 115
chr2_-_170430312 0.368 NM_024622
FASTKD1
FAST kinase domains 1
chr17_-_62097937 0.365 NM_001099786
NM_001099787
NM_001099788
NM_001099789
ICAM2



intercellular adhesion molecule 2



chr2_+_48807725 0.365 NM_001198594
STON1
STON1-GTF2A1L
stonin 1
STON1-GTF2A1L readthrough
chr6_+_54173202 0.361 NM_014464
TINAG
tubulointerstitial nephritis antigen
chr2_-_99917638 0.359 NM_174898
LYG1
lysozyme G-like 1
chr5_-_64777703 0.358 NM_197941
ADAMTS6
ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr11_-_30601919 0.356 NM_001584
MPPED2
metallophosphoesterase domain containing 2
chr12_-_371994 0.355 NM_001190997
NM_001243392
NM_016615
SLC6A13


solute carrier family 6 (neurotransmitter transporter, GABA), member 13


chr1_+_196946666 0.355 NM_030787
CFHR5
complement factor H-related 5
chr6_-_68598987 0.350 ERVH-3
endogenous retrovirus group H, member 3
chr7_-_108142934 0.346 PNPLA8
patatin-like phospholipase domain containing 8
chr5_+_40909617 0.345 C7
complement component 7
chr3_+_171561138 0.340 NM_001164436
TMEM212
transmembrane protein 212
chr9_+_6215785 0.339 NM_001199640
NM_001199641
NM_033439
IL33


interleukin 33


chr4_-_88450243 0.339 SPARCL1
SPARC-like 1 (hevin)
chr3_-_165555252 0.335 NM_000055
BCHE
butyrylcholinesterase
chr15_-_55652777 0.333 CCPG1
cell cycle progression 1
chr3_-_101039403 0.324 NM_016247
IMPG2
interphotoreceptor matrix proteoglycan 2
chr7_+_134212343 0.322 NM_020299
AKR1B10
aldo-keto reductase family 1, member B10 (aldose reductase)
chr8_+_18248754 0.321 NM_000015
NAT2
N-acetyltransferase 2 (arylamine N-acetyltransferase)
chr7_-_99527242 0.321 NM_181538
GJC3
gap junction protein, gamma 3, 30.2kDa
chr4_-_23891608 0.321 NM_013261
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr12_+_109551041 0.320


chr11_-_47736896 0.316 NM_024783
AGBL2
ATP/GTP binding protein-like 2
chr4_-_164534656 0.315 NM_017923
MARCH1
membrane-associated ring finger (C3HC4) 1
chr6_+_36644236 0.315 NM_001220777
NM_078467
CDKN1A

cyclin-dependent kinase inhibitor 1A (p21, Cip1)

chr17_+_56833231 0.314 NM_014906
PPM1E
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr11_-_5323174 0.312 NM_033179
OR51B4
olfactory receptor, family 51, subfamily B, member 4
chr12_-_8218930 0.312 NM_004054
C3AR1
complement component 3a receptor 1
chr12_-_11244828 0.310 NM_176884
TAS2R43
TAS2R31
taste receptor, type 2, member 43
taste receptor, type 2, member 31
chr21_+_34638670 0.308 NM_000628
IL10RB
interleukin 10 receptor, beta
chr1_+_198608136 0.307 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr4_+_170581212 0.306 NM_001243374
CLCN3
chloride channel 3
chr4_+_159131400 0.305 NM_018342
TMEM144
transmembrane protein 144
chrX_-_21776158 0.304 NM_014332
SMPX
small muscle protein, X-linked
chr7_-_74267824 0.302 NM_173537
GTF2IRD2B
GTF2IRD2
GTF2I repeat domain containing 2B
GTF2I repeat domain containing 2
chr1_+_206730591 0.301 RASSF5
Ras association (RalGDS/AF-6) domain family member 5
chr4_+_88896899 0.300 SPP1
secreted phosphoprotein 1
chr2_-_217560247 0.299 NM_000599
IGFBP5
insulin-like growth factor binding protein 5
chr4_+_186990308 0.298 NM_003265
TLR3
toll-like receptor 3
chr4_+_74270832 0.298 ALB
albumin
chr3_-_185270258 0.298 NM_139248
LIPH
lipase, member H
chr17_-_38859976 0.297 NM_019016
KRT24
keratin 24
chr2_-_77749335 0.295 NM_001134745
NM_024993
LRRTM4

leucine rich repeat transmembrane neuronal 4

chr5_-_16509106 0.293 NM_019000
FAM134B
family with sequence similarity 134, member B
chr8_-_122653493 0.293 NM_005328
HAS2
hyaluronan synthase 2
chr13_-_103346847 0.286 NM_001010977
METTL21C
methyltransferase like 21C
chr10_-_62332666 0.282 NM_001204404
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr6_+_50786438 0.281 NM_003221
TFAP2B
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
chr7_+_141408152 0.281 NM_001105558
WEE2
WEE1 homolog 2 (S. pombe)
chr2_-_71062904 0.278 NM_015717
CD207
CD207 molecule, langerin
chr15_-_77154284 0.276 NM_001145923
SCAPER
S-phase cyclin A-associated protein in the ER
chr11_-_124546198 0.274 NM_001199922
SIAE
sialic acid acetylesterase
chr12_-_95945226 0.270 NM_032147
USP44
ubiquitin specific peptidase 44
chr10_+_695887 0.269 C10orf108
chromosome 10 open reading frame 108
chr2_-_28113954 0.265 LOC100302650
uncharacterized LOC100302650
chr16_-_54962707 0.262 CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr19_-_56704420 0.259 NM_001080456
ZSCAN5B
zinc finger and SCAN domain containing 5B
chr2_+_207406815 0.259 ADAM23
ADAM metallopeptidase domain 23
chr10_+_88985204 0.256 NM_001099338
FAM22A
FAM22D
family with sequence similarity 22, member A
family with sequence similarity 22, member D
chr8_-_30585442 0.254 NM_000637
NM_001195102
NM_001195103
NM_001195104
GSR



glutathione reductase



chr12_-_11175169 0.254 NM_176888
TAS2R19
taste receptor, type 2, member 19
chr12_+_27619742 0.254 NM_001145010
C12orf70
chromosome 12 open reading frame 70
chr19_-_13617037 0.253 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr9_+_70856838 0.252 NM_201453
CBWD5
CBWD3
CBWD6
COBW domain containing 5
COBW domain containing 3
COBW domain containing 6
chr10_+_89267589 0.251 NM_001178118
MINPP1
multiple inositol-polyphosphate phosphatase 1
chr1_-_169680677 0.248 NM_000655
SELL
selectin L
chr15_+_69606741 0.247 NM_001104554
PAQR5
progestin and adipoQ receptor family member V
chr10_+_77542518 0.247 NM_032024
C10orf11
chromosome 10 open reading frame 11
chr6_+_131894343 0.246 NM_000045
NM_001244438
ARG1

arginase, liver

chr7_+_28475233 0.246 NM_004904
CREB5
cAMP responsive element binding protein 5
chr6_+_26020677 0.246 NM_003529
HIST1H3A
histone cluster 1, H3a
chr5_+_40909487 0.244 C7
complement component 7
chr2_-_238499317 0.244 RAB17
RAB17, member RAS oncogene family
chr1_+_104097321 0.242 NM_020978
AMY2B
amylase, alpha 2B (pancreatic)
chr4_-_90759446 0.242 NM_001146055
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr3_-_155394104 0.241 NM_001130960
NM_001130961
PLCH1

phospholipase C, eta 1

chrX_-_34150427 0.241 NM_203408
FAM47A
family with sequence similarity 47, member A
chr7_-_7575449 0.241 NM_001037763
COL28A1
collagen, type XXVIII, alpha 1
chr12_+_100041527 0.240 NM_153364
FAM71C
family with sequence similarity 71, member C
chr13_+_25670275 0.240 NM_030979
PABPC3
poly(A) binding protein, cytoplasmic 3
chr2_+_210444364 0.239 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr12_-_81991959 0.239 NM_001220477
NM_001220478
PPFIA2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr6_+_22569656 0.239 NM_138574
HDGFL1
hepatoma derived growth factor-like 1
chr11_+_36589562 0.238 NM_000448
RAG1
recombination activating gene 1
chr7_-_99474655 0.238 NM_001005276
OR2AE1
olfactory receptor, family 2, subfamily AE, member 1
chr1_-_89641722 0.238 NM_207398
GBP7
guanylate binding protein 7
chr1_-_203317366 0.238 FMOD
fibromodulin
chr4_-_2230957 0.236 NM_181808
POLN
polymerase (DNA directed) nu
chr20_-_23066828 0.236 NM_012072
CD93
CD93 molecule
chr2_+_183943511 0.235 DUSP19
dual specificity phosphatase 19
chr14_-_74025643 0.235 NM_001220484
NM_203309
HEATR4

HEAT repeat containing 4

chr4_-_52883785 0.231 NM_001024611
LRRC66
leucine rich repeat containing 66
chr1_+_79086087 0.230 NM_006820
IFI44L
interferon-induced protein 44-like
chr1_-_102462789 0.229 NM_058170
OLFM3
olfactomedin 3
chr6_-_43595046 0.229 GTPBP2
GTP binding protein 2
chr12_+_18414473 0.229 NM_004570
PIK3C2G
phosphoinositide-3-kinase, class 2, gamma polypeptide
chr18_+_19353635 0.228 MIB1
mindbomb homolog 1 (Drosophila)
chr6_+_139349877 0.228 C6orf115
chromosome 6 open reading frame 115
chr11_+_124134699 0.228 NM_001005198
OR8G5
olfactory receptor, family 8, subfamily G, member 5
chr19_-_44831907 0.227 ZFP112
zinc finger protein 112 homolog (mouse)
chr1_-_207205996 0.227 NM_001083924
NM_023938
C1orf116

chromosome 1 open reading frame 116

chrX_-_77225134 0.226 NM_001029891
PGAM4
phosphoglycerate mutase family member 4
chr2_+_158114109 0.224 NM_014568
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chrX_-_138914384 0.223 NM_001010986
NM_173694
ATP11C

ATPase, class VI, type 11C

chr9_+_92219926 0.223 NM_006705
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr9_+_126773851 0.223 NM_004789
LHX2
LIM homeobox 2
chrX_+_54834107 0.222 NM_177433
MAGED2
melanoma antigen family D, 2
chr19_+_47813074 0.221 NM_001736
C5AR1
complement component 5a receptor 1
chr12_-_53600999 0.221 NM_000889
ITGB7
integrin, beta 7
chr3_-_10334600 0.220 NM_001134944
NM_001134945
NM_001134946
GHRL


ghrelin/obestatin prepropeptide


chr17_-_67311773 0.219 NM_018672
ABCA5
ATP-binding cassette, sub-family A (ABC1), member 5
chr4_-_153601085 0.219 NM_152680
TMEM154
transmembrane protein 154
chr2_-_165811995 0.218 NM_001199148
NM_173512
SLC38A11

solute carrier family 38, member 11

chr20_+_1306033 0.217 LOC100507495
uncharacterized LOC100507495
chr6_-_119470336 0.216 NM_001100411
FAM184A
family with sequence similarity 184, member A
chr12_+_48516428 0.215 NM_001166687
NM_001166688
PFKM

phosphofructokinase, muscle

chr22_-_37164073 0.215 NM_001177702
IFT27
intraflagellar transport 27 homolog (Chlamydomonas)
chr10_+_51837885 0.214 NM_018232
FAM21B
family with sequence similarity 21, member B
chr19_-_48614013 0.214 NM_001159322
NM_001159323
NM_003706
PLA2G4C


phospholipase A2, group IVC (cytosolic, calcium-independent)


chrX_-_10645726 0.214 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr8_+_99076749 0.213 NM_001170806
NM_173549
C8orf47

chromosome 8 open reading frame 47

chr3_-_155524037 0.212 NM_173657
C3orf33
chromosome 3 open reading frame 33
chr1_-_148176392 0.212


chr4_+_74269971 0.211 NM_000477
ALB
albumin
chr10_+_5005685 0.211 AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr3_-_46249787 0.209 NM_001295
CCR1
chemokine (C-C motif) receptor 1
chrX_-_10535476 0.209 NM_001193278
NM_001193279
NM_001193280
NM_001193281
MID1



midline 1 (Opitz/BBB syndrome)



chr17_+_56833206 0.208 PPM1E
protein phosphatase, Mg2+/Mn2+ dependent, 1E

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.