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• Activity deltas table
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Motif ID: HMX1.p2

Z-value: 1.239

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_+_182569427	1.932
chr8_+_32405727	1.446	NM_001160002 NM_001160004 NM_001160005 NM_001160007 NM_001160008 NM_004495 NM_013956 NM_013957 NM_013958 NM_013960 NM_013964	NRG1	neuregulin 1
chr16_-_776366	1.358	NM_001031737	CCDC78	coiled-coil domain containing 78
chr8_-_29207795	1.208	NM_001394	DUSP4	dual specificity phosphatase 4
chr8_+_128806720	1.172		PVT1	Pvt1 oncogene (non-protein coding)
chr11_-_63933493	1.163	NM_014067	MACROD1	MACRO domain containing 1
chr13_+_42031679	1.044		C13orf15	chromosome 13 open reading frame 15
chr13_+_42031525	0.999	NM_014059	C13orf15	chromosome 13 open reading frame 15
chr13_+_42031690	0.933		C13orf15	chromosome 13 open reading frame 15
chr11_+_64692052	0.911	NM_006244	PPP2R5B	protein phosphatase 2, regulatory subunit B', beta
chr3_-_172166202	0.908	NM_004122 NM_198407	GHSR	growth hormone secretagogue receptor
chr12_+_57482674	0.881	NM_005967	NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)
chr19_+_50796820	0.861		MYH14	myosin, heavy chain 14, non-muscle
chr6_+_30130982	0.855	NM_033229	TRIM15	tripartite motif containing 15
chr17_-_72968790	0.802	NM_030630	C17orf28	chromosome 17 open reading frame 28
chr19_-_18385166	0.781	NM_001145304 NM_001145305 NM_025249	KIAA1683	KIAA1683
chr12_-_112819755	0.780	NM_001109662	C12orf51	chromosome 12 open reading frame 51
chr11_-_65667809	0.770		FOSL1	FOS-like antigen 1
chr2_+_132250500	0.770		LOC150776	sphingomyelin phosphodiesterase 4, neutral membrane pseudogene
chr12_+_57482922	0.765		NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)
chr6_+_36646489	0.765		CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr17_-_62097937	0.742	NM_001099786 NM_001099787 NM_001099788 NM_001099789	ICAM2	intercellular adhesion molecule 2
chr12_+_57482886	0.728		NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)
chr17_-_72968750	0.716
chr19_-_46285746	0.714		DMPK	dystrophia myotonica-protein kinase
chr7_-_155601757	0.711		SHH	sonic hedgehog
chr11_-_63933204	0.709		MACROD1	MACRO domain containing 1
chr16_+_3062456	0.687	NM_020982	CLDN9	claudin 9
chr10_-_99531712	0.685	NM_003015	SFRP5	secreted frizzled-related protein 5
chr4_-_82393025	0.684	NM_152545	RASGEF1B	RasGEF domain family, member 1B
chr6_-_41673677	0.666		TFEB	transcription factor EB
chr19_-_42721802	0.649	NM_133328	DEDD2	death effector domain containing 2
chr1_+_86046434	0.648	NM_001554	CYR61	cysteine-rich, angiogenic inducer, 61
chr11_+_537521	0.629	NM_198075	LRRC56	leucine rich repeat containing 56
chr5_+_141016567	0.627		RELL2	RELT-like 2
chr2_+_27346656	0.623	NM_032604	ABHD1	abhydrolase domain containing 1
chr19_-_46285645	0.621		DMPK	dystrophia myotonica-protein kinase
chr4_-_82392971	0.620		RASGEF1B	RasGEF domain family, member 1B
chr5_+_76114832	0.620	NM_005242	F2RL1	coagulation factor II (thrombin) receptor-like 1
chr6_-_56716713	0.613		DST	dystonin
chr6_+_16238780	0.605	NM_006877	GMPR	guanosine monophosphate reductase
chr11_-_65667860	0.597	NM_005438	FOSL1	FOS-like antigen 1
chr6_+_36644236	0.592	NM_001220777 NM_078467	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr5_+_141016516	0.590	NM_001130029 NM_173828	RELL2	RELT-like 2
chr11_+_59522905	0.589		STX3	syntaxin 3
chr7_+_1580009	0.586		MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr1_+_236305831	0.584	NM_003272	GPR137B	G protein-coupled receptor 137B
chr4_-_54457628	0.574		LNX1	ligand of numb-protein X 1
chr17_+_19314490	0.571	NM_007148	RNF112	ring finger protein 112
chr15_+_75639330	0.569	NM_024608	NEIL1	nei endonuclease VIII-like 1 (E. coli)
chr4_-_74486100	0.566	NM_177532 NM_201431	RASSF6	Ras association (RalGDS/AF-6) domain family member 6
chr5_-_138718941	0.565		SLC23A1	solute carrier family 23 (nucleobase transporters), member 1
chr19_-_46285752	0.546	NM_001081560 NM_001081562 NM_004409	DMPK	dystrophia myotonica-protein kinase
chr1_-_201915467	0.543		LMOD1	leiomodin 1 (smooth muscle)
chr22_+_40766649	0.539		SGSM3	small G protein signaling modulator 3
chr12_-_112037024	0.537		ATXN2	ataxin 2
chr19_+_676346	0.536	NM_005860	FSTL3	follistatin-like 3 (secreted glycoprotein)
chr17_-_74722843	0.528	NM_001081461 NM_015167	JMJD6	jumonji domain containing 6
chr11_+_59522801	0.527		STX3	syntaxin 3
chr7_+_128470462	0.527	NM_001127487 NM_001458	FLNC	filamin C, gamma
chr19_+_4969123	0.526	NM_015015	KDM4B	lysine (K)-specific demethylase 4B
chr12_+_122356446	0.525	NM_001178003 NM_144668	WDR66	WD repeat domain 66
chr22_+_41488607	0.524	NM_001429	EP300	E1A binding protein p300
chr1_+_95583478	0.523	NM_001199691	TMEM56-RWDD3	TMEM56-RWDD3 readthrough
chr9_+_5890801	0.519	NM_005511	MLANA	melan-A
chr17_-_79212884	0.519	NM_144679	C17orf56	chromosome 17 open reading frame 56
chr12_+_50497790	0.518	NM_005276	GPD1	glycerol-3-phosphate dehydrogenase 1 (soluble)
chr19_+_49375677	0.518		PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr16_+_67197287	0.514	NM_001040667 NM_001538	HSF4	heat shock transcription factor 4
chr3_+_57994087	0.512	NM_001164317 NM_001164318 NM_001164319 NM_001457	FLNB	filamin B, beta
chr12_-_112036867	0.512		ATXN2	ataxin 2
chr22_-_37640287	0.511	NM_002872	RAC2	ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chrX_-_153210057	0.510	NM_002910	RENBP	renin binding protein
chr4_-_2420252	0.505	NM_001172656 NM_001172657 NM_001172658 NM_020972	ZFYVE28	zinc finger, FYVE domain containing 28
chr19_+_55987698	0.503	NM_033113	ZNF628	zinc finger protein 628
chr19_-_1174263	0.502	NM_014963	SBNO2	strawberry notch homolog 2 (Drosophila)
chr6_-_56716412	0.501		DST	dystonin
chr5_-_138719018	0.491	NM_005847 NM_152685	SLC23A1	solute carrier family 23 (nucleobase transporters), member 1
chr22_+_40766636	0.485		SGSM3	small G protein signaling modulator 3
chr7_+_74508346	0.484	NM_001003795	GTF2IRD2B GTF2IRD2	GTF2I repeat domain containing 2B GTF2I repeat domain containing 2
chr1_+_145524989	0.483	NM_003637	ITGA10	integrin, alpha 10
chr6_+_2245965	0.482
chr5_+_76114881	0.481		F2RL1	coagulation factor II (thrombin) receptor-like 1
chr16_-_67978422	0.477		SLC12A4	solute carrier family 12 (potassium/chloride transporters), member 4
chr19_-_1174257	0.474		SBNO2	strawberry notch homolog 2 (Drosophila)
chr16_-_88752879	0.473	NM_178310	SNAI3	snail homolog 3 (Drosophila)
chr22_+_40766617	0.463		SGSM3	small G protein signaling modulator 3
chr3_+_5021096	0.461	NM_003670	BHLHE40	basic helix-loop-helix family, member e40
chr19_-_1174201	0.461
chr8_-_95274540	0.459	NM_005261 NM_181702	GEM	GTP binding protein overexpressed in skeletal muscle
chr22_+_40766630	0.458		SGSM3	small G protein signaling modulator 3
chr16_-_3074225	0.456	NM_001002017 NM_001002018 NM_017885	HCFC1R1	host cell factor C1 regulator 1 (XPO1 dependent)
chr17_-_7166263	0.455	NM_001185023 NM_001307	CLDN7	claudin 7
chr22_+_40766563	0.455	NM_015705	SGSM3	small G protein signaling modulator 3
chr6_-_31550065	0.451	NM_002341 NM_009588	LTB	lymphotoxin beta (TNF superfamily, member 3)
chr19_+_49375638	0.450	NM_014330	PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr18_+_55888750	0.447	NM_001144966	NEDD4L	neural precursor cell expressed, developmentally down-regulated 4-like
chr1_+_11539177	0.438	NM_020780	PTCHD2	patched domain containing 2
chr1_-_196577438	0.434	NM_198503	KCNT2	potassium channel, subfamily T, member 2
chr19_+_41305333	0.434	NM_053046	EGLN2	egl nine homolog 2 (C. elegans)
chr5_+_141016987	0.434		RELL2	RELT-like 2
chr4_+_24797203	0.428		SOD3	superoxide dismutase 3, extracellular
chr16_-_67193804	0.427	NM_003789	TRADD	TNFRSF1A-associated via death domain
chr16_-_70713927	0.426		MTSS1L	metastasis suppressor 1-like
chr12_-_54778298	0.426		ZNF385A	zinc finger protein 385A
chr22_-_39268169	0.426		CBX6	chromobox homolog 6
chr1_+_212797788	0.422	NM_153606	FAM71A	family with sequence similarity 71, member A
chr3_-_129830273	0.418
chr3_+_5021305	0.417		BHLHE40	basic helix-loop-helix family, member e40
chr8_-_145018057	0.416	NM_201382	PLEC	plectin
chr7_-_130792839	0.416		FLJ43663	uncharacterized LOC378805
chr1_+_177140530	0.413	NM_021165	FAM5B	family with sequence similarity 5, member B
chr22_-_39268214	0.413		CBX6	chromobox homolog 6
chr20_+_49348050	0.411	NM_032521	PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)
chr5_-_37835928	0.410	NM_001190468 NM_001190469	GDNF	glial cell derived neurotrophic factor
chr7_+_156803599	0.410		LOC645249	uncharacterized LOC645249
chr17_-_74533623	0.410	NM_134268	CYGB	cytoglobin
chr5_+_68788387	0.409	NM_001205254	OCLN	occludin
chr12_+_58120029	0.406		LOC100130776	uncharacterized LOC100130776
chr22_-_38349533	0.406	NM_032561 NM_001207062	C22orf23	chromosome 22 open reading frame 23
chr1_+_156211950	0.403	NM_199173	BGLAP	bone gamma-carboxyglutamate (gla) protein
chr22_+_50781773	0.402		PPP6R2	protein phosphatase 6, regulatory subunit 2
chr10_-_30025754	0.401		SVIL	supervillin
chr8_+_8086103	0.400		FLJ10661	family with sequence similarity 86, member A pseudogene
chr8_+_31497267	0.400	NM_013962	NRG1	neuregulin 1
chr22_+_50781717	0.398	NM_001242898 NM_001242899 NM_001242900 NM_014678	PPP6R2	protein phosphatase 6, regulatory subunit 2
chr20_-_62601140	0.397	NM_020713	ZNF512B	zinc finger protein 512B
chr19_+_49375679	0.397		PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr12_-_50677238	0.395	NM_001113546 NM_016357	LIMA1	LIM domain and actin binding 1
chr12_-_112036257	0.393		ATXN2	ataxin 2
chr11_+_118992232	0.390	NM_001243259 NM_015517 NM_198971	HINFP	histone H4 transcription factor
chr16_+_3014216	0.388	NM_001253725 NM_001253726 NM_024507 NM_172229	KREMEN2	kringle containing transmembrane protein 2
chr1_-_109584589	0.386	NM_001142550 NM_001142551 NM_014969	WDR47	WD repeat domain 47
chr3_+_5021141	0.384		BHLHE40	basic helix-loop-helix family, member e40
chr15_+_83776323	0.379	NM_001144903 NM_023003	TM6SF1	transmembrane 6 superfamily member 1
chr18_-_47721165	0.379	NM_001080467	MYO5B	myosin VB
chr16_-_48269087	0.378	NM_032583 NM_145186	ABCC11	ATP-binding cassette, sub-family C (CFTR/MRP), member 11
chr19_+_36209125	0.378		MLL4	myeloid/lymphoid or mixed-lineage leukemia 4
chr9_-_131940481	0.378		IER5L	immediate early response 5-like
chr10_+_99258615	0.374	NM_024954	UBTD1	ubiquitin domain containing 1
chr1_+_36554452	0.372	NM_017825	ADPRHL2	ADP-ribosylhydrolase like 2
chr5_-_81046858	0.372		SSBP2	single-stranded DNA binding protein 2
chr10_+_99258879	0.370
chrX_-_153599719	0.367		FLNA	filamin A, alpha
chr1_-_62190740	0.367		TM2D1	TM2 domain containing 1
chrX_-_153599581	0.367		FLNA	filamin A, alpha
chr17_-_8151373	0.365	NM_025099	CTC1	CTS telomere maintenance complex component 1
chr11_-_9113092	0.365	NM_001170690 NM_020974	SCUBE2	signal peptide, CUB domain, EGF-like 2
chr18_+_23806385	0.365	NM_005640	TAF4B	TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr11_+_63580922	0.362	NM_138471	C11orf84	chromosome 11 open reading frame 84
chr9_+_35605614	0.362		TESK1	testis-specific kinase 1
chr19_+_41305100	0.361		EGLN2	egl nine homolog 2 (C. elegans)
chr17_+_72428228	0.361		GPRC5C	G protein-coupled receptor, family C, group 5, member C
chr17_+_36283959	0.360	NM_001123391 NM_032258	TBC1D3C TBC1D3 TBC1D3F	TBC1 domain family, member 3C TBC1 domain family, member 3 TBC1 domain family, member 3F
chr8_-_95274520	0.360		GEM	GTP binding protein overexpressed in skeletal muscle
chr22_-_39268230	0.359	NM_014292	CBX6	chromobox homolog 6
chr4_-_54457723	0.357	NM_001126328	LNX1	ligand of numb-protein X 1
chr16_-_29606639	0.356
chr1_-_196577676	0.355		KCNT2	potassium channel, subfamily T, member 2
chr5_+_56110899	0.354	NM_005921	MAP3K1	mitogen-activated protein kinase kinase kinase 1
chr17_-_8151353	0.354		CTC1	CTS telomere maintenance complex component 1
chr1_+_43613593	0.353	NM_001101376	FAM183A	family with sequence similarity 183, member A
chr19_+_48673936	0.353		C19orf68	chromosome 19 open reading frame 68
chr11_-_65363466	0.352	NM_005714 NM_033347 NM_033348 NM_033455	KCNK7	potassium channel, subfamily K, member 7
chr16_-_88752788	0.351		SNAI3	snail homolog 3 (Drosophila)
chr7_-_100493481	0.350	NM_000665 NM_015831	ACHE	acetylcholinesterase
chr19_+_4969126	0.349		KDM4B	lysine (K)-specific demethylase 4B
chr14_-_105634708	0.348		JAG2	jagged 2
chr16_-_30583727	0.348	NM_001024683 NM_145271	ZNF688	zinc finger protein 688
chr14_+_55034633	0.348		SAMD4A	sterile alpha motif domain containing 4A
chr17_+_78194090	0.346	NM_001166347 NM_001166348 NM_001166349 NM_173626	SLC26A11	solute carrier family 26, member 11
chr7_-_36406446	0.345	NM_001199707 NM_001199706 NM_015314 NM_001199708	KIAA0895	KIAA0895
chr6_+_19838612	0.345
chr15_+_89182038	0.344	NM_002201	ISG20	interferon stimulated exonuclease gene 20kDa
chr6_-_43596764	0.342		GTPBP2	GTP binding protein 2
chr19_+_41305041	0.342	NM_080732	EGLN2	egl nine homolog 2 (C. elegans)
chr17_-_36762105	0.341	NM_025248	SRCIN1	SRC kinase signaling inhibitor 1
chr1_-_27286875	0.341	NM_152365	C1orf172	chromosome 1 open reading frame 172
chr9_-_131940538	0.334	NM_203434	IER5L	immediate early response 5-like
chr12_-_96184510	0.334	NM_021229	NTN4	netrin 4
chr2_+_219125737	0.333	NM_001077191 NM_001077194 NM_170699	GPBAR1	G protein-coupled bile acid receptor 1
chr10_+_11865310	0.333	NM_153256	C10orf47	chromosome 10 open reading frame 47
chr12_-_96184346	0.331		NTN4	netrin 4
chr11_-_62607043	0.330		WDR74	WD repeat domain 74
chrX_-_119379060	0.330		NKAPP1	NFKB activating protein pseudogene 1
chr12_-_58160823	0.330	NM_000785	CYP27B1	cytochrome P450, family 27, subfamily B, polypeptide 1
chr17_-_79876027	0.329		SIRT7	sirtuin 7
chr17_-_79875995	0.327		SIRT7	sirtuin 7
chr19_-_344778	0.326	NM_017550	MIER2	mesoderm induction early response 1, family member 2
chr1_+_226411318	0.326	NM_031944	MIXL1	Mix paired-like homeobox
chr2_-_172967627	0.326		DLX2	distal-less homeobox 2
chr18_-_21166378	0.325		NPC1	Niemann-Pick disease, type C1
chr11_+_46368881	0.324	NM_001199266 NM_001199267 NM_001199268 NM_003646	DGKZ	diacylglycerol kinase, zeta
chr17_+_42836546	0.323	NM_002390	ADAM11	ADAM metallopeptidase domain 11
chr20_+_48599511	0.319	NM_005985	SNAI1	snail homolog 1 (Drosophila)
chr3_+_39093480	0.318	NM_020839	WDR48	WD repeat domain 48
chr19_-_14606893	0.318		GIPC1	GIPC PDZ domain containing family, member 1
chr2_+_242498118	0.316	NM_032515	BOK	BCL2-related ovarian killer
chr1_+_201476283	0.316
chr16_+_83986826	0.314	NM_182981	OSGIN1	oxidative stress induced growth inhibitor 1

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
23.87	2.33e-03	GO:0045859	regulation of protein kinase activity
22.92	2.64e-03	GO:0043549	regulation of kinase activity
22.13	2.93e-03	GO:0051338	regulation of transferase activity
17.91	5.54e-03	GO:0001932	regulation of protein phosphorylation
16.84	6.68e-03	GO:0042325	regulation of phosphorylation
16.36	7.28e-03	GO:0019220	regulation of phosphate metabolic process
16.36	7.28e-03	GO:0051174	regulation of phosphorus metabolic process
14.29	1.09e-02	GO:0031399	regulation of protein modification process
11.23	2.27e-02	GO:0032268	regulation of cellular protein metabolic process
10.57	2.72e-02	GO:0051246	regulation of protein metabolic process
9.71	3.50e-02	GO:0050790	regulation of catalytic activity

Nothing significant found in compartment category.

Nothing significant found in function category.