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• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: HOX{A4,D4}.p2

Z-value: 0.918

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr10_-_92681025	2.566	NM_014391	ANKRD1	ankyrin repeat domain 1 (cardiac muscle)
chr12_-_10588543	1.194	NM_002260	KLRC2 KLRC3	killer cell lectin-like receptor subfamily C, member 2 killer cell lectin-like receptor subfamily C, member 3
chr10_-_92680784	1.082		ANKRD1	ankyrin repeat domain 1 (cardiac muscle)
chr19_+_45116921	0.946	NM_001205280	IGSF23	immunoglobulin superfamily, member 23
chr4_+_74606222	0.833	NM_000584	IL8	interleukin 8
chr3_-_47933997	0.819		MAP4	microtubule-associated protein 4
chr12_-_10324675	0.801	NM_001172632 NM_001172633 NM_002543	OLR1	oxidized low density lipoprotein (lectin-like) receptor 1
chr5_-_135290521	0.682	NM_002302	LECT2	leukocyte cell-derived chemotaxin 2
chr15_+_71433787	0.681	NM_024817	THSD4	thrombospondin, type I, domain containing 4
chr2_+_29038862	0.634	NM_001008779	SPDYA	speedy homolog A (Xenopus laevis)
chr11_-_46612913	0.620	NM_017749	AMBRA1	autophagy/beclin-1 regulator 1
chr8_-_42234562	0.588	NM_014420	DKK4	dickkopf homolog 4 (Xenopus laevis)
chr15_+_100173182	0.586	NM_001130928	MEF2A	myocyte enhancer factor 2A
chr3_-_57234279	0.578	NM_003865	HESX1	HESX homeobox 1
chr7_+_17382900	0.562		AHR	aryl hydrocarbon receptor
chr2_+_37571752	0.545	NM_012413	QPCT	glutaminyl-peptide cyclotransferase
chr6_-_26235160	0.529	NM_005320	HIST1H1D	histone cluster 1, H1d
chr3_-_114866090	0.515	NM_015642	ZBTB20	zinc finger and BTB domain containing 20
chr11_-_10590078	0.485	NM_006691	LYVE1	lymphatic vessel endothelial hyaluronan receptor 1
chr4_+_108814419	0.479	NM_001136257 NM_152621	SGMS2	sphingomyelin synthase 2
chr13_+_46276445	0.466	NM_152719	SPERT	spermatid associated
chrM_+_10704	0.457
chr7_+_28452143	0.433	NM_182898	CREB5	cAMP responsive element binding protein 5
chr8_-_13372183	0.428	NM_024767 NM_182643	DLC1	deleted in liver cancer 1
chr4_-_74864296	0.416	NM_002994	CXCL5	chemokine (C-X-C motif) ligand 5
chr7_+_128312345	0.411	NM_001012454 NM_001128926	FAM71F2	family with sequence similarity 71, member F2
chr1_-_156460390	0.409		MEF2D	myocyte enhancer factor 2D
chr22_-_37975937	0.392	NM_006498	LGALS2	lectin, galactoside-binding, soluble, 2
chr1_-_221915393	0.389		DUSP10	dual specificity phosphatase 10
chr10_+_28878666	0.386		WAC	WW domain containing adaptor with coiled-coil
chr1_+_167298382	0.384		POU2F1	POU class 2 homeobox 1
chr5_-_74326723	0.357	NM_016591	GCNT4	glucosaminyl (N-acetyl) transferase 4, core 2
chr1_+_47881743	0.355	NM_012186	FOXE3	forkhead box E3
chr1_-_221915426	0.351		DUSP10	dual specificity phosphatase 10
chr7_-_122339186	0.348	NM_139175	RNF133	ring finger protein 133
chr4_+_2627158	0.346	NM_003704	FAM193A	family with sequence similarity 193, member A
chr17_-_7493389	0.340	NM_006942	SOX15	SRY (sex determining region Y)-box 15
chrM_+_4770	0.337
chr7_+_28338939	0.336	NM_182899	CREB5	cAMP responsive element binding protein 5
chr17_-_39092714	0.334		KRT23	keratin 23 (histone deacetylase inducible)
chr5_+_149997205	0.330	NM_001166209	SYNPO	synaptopodin
chr19_-_47735858	0.322	NM_001127240 NM_001127241 NM_001127242	BBC3	BCL2 binding component 3
chr3_+_63884074	0.321	NM_001177387	ATXN7	ataxin 7
chrM_+_11427	0.319
chr12_-_70093064	0.317	NM_032735	BEST3	bestrophin 3
chrX_+_48916515	0.315	NM_001163322 NM_033626 NM_001163321 NM_001163323	CCDC120	coiled-coil domain containing 120
chr2_-_208994408	0.312	NM_020989	CRYGC	crystallin, gamma C
chr13_+_99058147	0.310
chr1_+_54359859	0.306	NM_000792 NM_001039715 NM_001039716 NM_213593	DIO1	deiodinase, iodothyronine, type I
chr6_-_41703938	0.304	NM_001167827	TFEB	transcription factor EB
chr3_-_114102488	0.303	NM_001164342	ZBTB20	zinc finger and BTB domain containing 20
chr17_+_7384720	0.301	NM_001102614	SLC35G6	solute carrier family 35, member G6
chr2_+_169643048	0.301	NM_001171631	NOSTRIN	nitric oxide synthase trafficker
chr14_-_81864726	0.295	NM_033104	STON2	stonin 2
chr9_-_104145800	0.294	NM_001127610	BAAT	bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr5_+_76382458	0.293		LOC728723	uncharacterized LOC728723
chr6_+_31514627	0.292	NM_001144962 NM_001144963	NFKBIL1	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr19_+_10222196	0.288	NM_002566	P2RY11	purinergic receptor P2Y, G-protein coupled, 11
chr19_-_57968106	0.279	NM_020633	VN1R1	vomeronasal 1 receptor 1
chr13_-_60325073	0.278
chr4_-_170077807	0.277		SH3RF1	SH3 domain containing ring finger 1
chr19_-_48614013	0.276	NM_001159322 NM_001159323 NM_003706	PLA2G4C	phospholipase A2, group IVC (cytosolic, calcium-independent)
chr7_+_18330044	0.274		HDAC9	histone deacetylase 9
chr5_+_134303595	0.271	NM_178019	CATSPER3	cation channel, sperm associated 3
chrM_+_11723	0.269
chr21_-_27253197	0.268		APP	amyloid beta (A4) precursor protein
chr3_-_114343052	0.265	NM_001164347	ZBTB20	zinc finger and BTB domain containing 20
chr2_+_27505296	0.263	NM_032546 NM_187841	TRIM54	tripartite motif containing 54
chr15_-_77472659	0.262		PEAK1	NKF3 kinase family member
chr19_-_46283763	0.257	NM_001081563	DMPK	dystrophia myotonica-protein kinase
chr13_-_41593405	0.257		ELF1	E74-like factor 1 (ets domain transcription factor)
chr9_+_75766777	0.256	NM_000700	ANXA1	annexin A1
chr7_+_18535817	0.250	NM_058176 NM_178425	HDAC9	histone deacetylase 9
chr3_-_20053618	0.249	NM_001252657	PP2D1	protein phosphatase 2C-like domain containing 1
chr6_-_31648140	0.248	NM_025262	LY6G5C	lymphocyte antigen 6 complex, locus G5C
chr19_+_49375677	0.248		PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chrM_+_4465	0.245
chr19_+_49375679	0.244		PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr12_+_52416615	0.241	NM_001202233	NR4A1	nuclear receptor subfamily 4, group A, member 1
chr6_-_53530505	0.240	NM_001003760	KLHL31	kelch-like 31 (Drosophila)
chrM_+_11676	0.240
chr8_-_72268720	0.239	NM_172058 NM_172059 NM_172060	EYA1	eyes absent homolog 1 (Drosophila)
chr5_-_88119604	0.236	NM_001193348 NM_001193349	MEF2C	myocyte enhancer factor 2C
chr19_-_1021122	0.235	NM_001033026 NM_033420	C19orf6	chromosome 19 open reading frame 6
chr4_-_66536182	0.233		EPHA5	EPH receptor A5
chr1_+_145524989	0.233	NM_003637	ITGA10	integrin, alpha 10
chr12_-_10021932	0.233		CLEC2B	C-type lectin domain family 2, member B
chr14_+_51026742	0.231	NM_015915 NM_181598	ATL1	atlastin GTPase 1
chr14_+_21756135	0.231	NM_020366	RPGRIP1	retinitis pigmentosa GTPase regulator interacting protein 1
chr17_-_67138013	0.229	NM_080284	ABCA6	ATP-binding cassette, sub-family A (ABC1), member 6
chr6_+_17282931	0.226	NM_153020	RBM24	RNA binding motif protein 24
chr19_+_49375638	0.224	NM_014330	PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr12_-_11139510	0.224	NM_176890	TAS2R50	taste receptor, type 2, member 50
chr19_+_18391252	0.224
chr1_+_151739130	0.223	NM_016178	OAZ3	ornithine decarboxylase antizyme 3
chr2_+_223916861	0.222	NM_080671	KCNE4	potassium voltage-gated channel, Isk-related family, member 4
chr1_-_221915458	0.222	NM_007207 NM_144729	DUSP10	dual specificity phosphatase 10
chr8_+_76452202	0.220	NM_004133	HNF4G	hepatocyte nuclear factor 4, gamma
chr22_+_22676814	0.220
chr2_-_225370687	0.217		CUL3	cullin 3
chr12_-_10573041	0.217	NM_002261 NM_007333	KLRC3	killer cell lectin-like receptor subfamily C, member 3
chr1_+_161676761	0.217	NM_001184866 NM_001184867 NM_001184870 NM_001184871 NM_001184872 NM_001184873 NM_032738	FCRLA	Fc receptor-like A
chr12_-_10562142	0.216	NM_013431	KLRC4-KLRK1 KLRC4	KLRC4-KLRK1 readthrough killer cell lectin-like receptor subfamily C, member 4
chr4_+_72897520	0.215	NM_004885	NPFFR2	neuropeptide FF receptor 2
chr11_+_5968576	0.215	NM_001003443	OR56A3	olfactory receptor, family 56, subfamily A, member 3
chr13_-_41593491	0.214	NM_172373	ELF1	E74-like factor 1 (ets domain transcription factor)
chr10_+_126630691	0.213	NM_017580	ZRANB1	zinc finger, RAN-binding domain containing 1
chr20_-_44006876	0.212	NM_014477	TP53TG5	TP53 target 5
chr16_+_3070310	0.211	NM_016639	TNFRSF12A	tumor necrosis factor receptor superfamily, member 12A
chr20_+_33299779	0.207		TP53INP2	tumor protein p53 inducible nuclear protein 2
chr12_-_102874340	0.206		IGF1	insulin-like growth factor 1 (somatomedin C)
chr12_-_57644905	0.205	NM_145064	STAC3	SH3 and cysteine rich domain 3
chr19_+_48758931	0.205		LOC100505812	uncharacterized LOC100505812
chr2_-_216249682	0.205		FN1	fibronectin 1
chr19_-_15391261	0.205	NM_014299 NM_058243	BRD4	bromodomain containing 4
chrX_+_41548225	0.204	NM_001097579 NM_005300	GPR34	G protein-coupled receptor 34
chr17_-_3461030	0.203		TRPV3	transient receptor potential cation channel, subfamily V, member 3
chr7_+_28725597	0.203	NM_001011666	CREB5	cAMP responsive element binding protein 5
chr7_+_112120907	0.202	NM_001134468 NM_182597	C7orf53	chromosome 7 open reading frame 53
chr1_+_167298280	0.201	NM_001198783	POU2F1	POU class 2 homeobox 1
chr5_+_69696805	0.199		SMA4	glucuronidase, beta pseudogene
chr18_-_47792773	0.197	NM_145020	CCDC11	coiled-coil domain containing 11
chr1_+_177140062	0.196		FAM5B	family with sequence similarity 5, member B
chr9_+_35560424	0.196		RUSC2	RUN and SH3 domain containing 2
chr3_+_88188261	0.191	NM_018293	ZNF654	zinc finger protein 654
chr14_-_92198383	0.190	NM_024764	CATSPERB	cation channel, sperm-associated, beta
chr1_-_161279724	0.189	NM_000530	MPZ	myelin protein zero
chr3_-_114790221	0.189	NM_001164343	ZBTB20	zinc finger and BTB domain containing 20
chr19_-_1020995	0.188		C19orf6	chromosome 19 open reading frame 6
chr3_+_32993065	0.187	NM_005508	CCR4	chemokine (C-C motif) receptor 4
chr11_-_83393436	0.187	NM_001142702	DLG2	discs, large homolog 2 (Drosophila)
chr10_+_99498233	0.187	NM_001002261	ZFYVE27	zinc finger, FYVE domain containing 27
chrX_+_107288199	0.186	NM_001170553 NM_182607	VSIG1	V-set and immunoglobulin domain containing 1
chr7_-_143956720	0.186	NM_001005328	OR2A7	olfactory receptor, family 2, subfamily A, member 7
chr1_-_89641722	0.184	NM_207398	GBP7	guanylate binding protein 7
chr4_-_76944585	0.183	NM_001565	CXCL10	chemokine (C-X-C motif) ligand 10
chr16_+_28699878	0.182	NM_001199142	EIF3C	eukaryotic translation initiation factor 3, subunit C
chr9_+_75766794	0.182		ANXA1	annexin A1
chr1_+_178310605	0.181	NM_004841	RASAL2	RAS protein activator like 2
chr15_+_40294749	0.180		EIF2AK4	eukaryotic translation initiation factor 2 alpha kinase 4
chr16_-_21436657	0.179	NM_130464	NPIPL3	nuclear pore complex interacting protein-like 3
chr12_-_52225700	0.179	NM_001013690	FIGNL2	fidgetin-like 2
chr20_+_32150139	0.178	NM_001039709 NM_005093	CBFA2T2	core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr12_-_102874373	0.178	NM_000618 NM_001111283 NM_001111285	IGF1	insulin-like growth factor 1 (somatomedin C)
chr13_+_97928414	0.177		MBNL2	muscleblind-like 2 (Drosophila)
chr1_-_150738292	0.177	NM_001199739 NM_004079	CTSS	cathepsin S
chr3_+_63953419	0.177	NM_001128149	ATXN7	ataxin 7
chrX_-_153210057	0.176	NM_002910	RENBP	renin binding protein
chr9_-_85882093	0.175	NM_001244962	FRMD3	FERM domain containing 3
chr17_-_79838899	0.173
chr2_+_109204904	0.172	NM_001193488	LIMS1	LIM and senescent cell antigen-like domains 1
chr1_+_202091971	0.172	NM_004767	GPR37L1	G protein-coupled receptor 37 like 1
chr11_+_112046207	0.172	NM_031938	BCO2	beta-carotene oxygenase 2
chr19_-_893184	0.172		MED16	mediator complex subunit 16
chr1_+_160160284	0.169	NM_001231	CASQ1	calsequestrin 1 (fast-twitch, skeletal muscle)
chr3_+_29322802	0.169	NM_001003792 NM_001003793 NM_001177711 NM_001177712 NM_014483	RBMS3	RNA binding motif, single stranded interacting protein 3
chr16_+_27341305	0.169		IL4R	interleukin 4 receptor
chr3_+_115342302	0.168		GAP43	growth associated protein 43
chr7_+_143792140	0.167	NM_001004135	OR2A12	olfactory receptor, family 2, subfamily A, member 12
chrX_-_49121171	0.167	NM_001114377 NM_014009	FOXP3	forkhead box P3
chr7_-_87342569	0.167	NM_000927	ABCB1	ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr3_-_189840225	0.167	NM_001134418	LEPREL1	leprecan-like 1
chr8_-_109799769	0.166	NM_153015	TMEM74	transmembrane protein 74
chr7_+_116395440	0.164
chr7_-_98805088	0.164	NM_001145715	KPNA7	karyopherin alpha 7 (importin alpha 8)
chr19_-_4338750	0.163	NM_001013841 NM_017720	STAP2	signal transducing adaptor family member 2
chr6_+_100054649	0.163	NM_021620	PRDM13	PR domain containing 13
chr22_+_26138168	0.163		MYO18B	myosin XVIIIB
chr19_+_11457239	0.163		CCDC159	coiled-coil domain containing 159
chr6_+_152011630	0.162	NM_001122742	ESR1	estrogen receptor 1
chr22_-_42336222	0.162	NM_001110215	CENPM	centromere protein M
chr2_-_69098502	0.162	NM_014482	BMP10	bone morphogenetic protein 10
chr1_+_16068916	0.162	NM_001013641	TMEM82	transmembrane protein 82
chr7_-_141541220	0.161	NM_001008270 NM_001171951	PRSS37	protease, serine, 37
chr3_+_46619075	0.161	NM_003212	TDGF1	teratocarcinoma-derived growth factor 1
chr19_+_45971249	0.161	NM_001114171 NM_006732	FOSB	FBJ murine osteosarcoma viral oncogene homolog B
chr12_-_113841654	0.161	NM_006843	SDS	serine dehydratase
chr12_-_50616425	0.160	NM_001113547	LIMA1	LIM domain and actin binding 1
chr6_+_17393610	0.160	NM_006366	CAP2	CAP, adenylate cyclase-associated protein, 2 (yeast)
chr4_+_68424444	0.160	NM_012108	STAP1	signal transducing adaptor family member 1
chr1_-_155649597	0.160	NM_001198899	YY1AP1	YY1 associated protein 1
chr1_+_10509775	0.160	NM_001302	CORT	cortistatin
chr8_-_145060594	0.160	NM_032789	PARP10	poly (ADP-ribose) polymerase family, member 10
chr11_-_104827421	0.159	NM_033306	CASP4	caspase 4, apoptosis-related cysteine peptidase
chrM_+_10123	0.159
chr14_-_54423448	0.159	NM_001202 NM_130850	BMP4	bone morphogenetic protein 4
chr11_-_84634437	0.159	NM_001364	DLG2	discs, large homolog 2 (Drosophila)
chr2_+_87144737	0.158	NM_001024457	RGPD1	RANBP2-like and GRIP domain containing 1
chr11_-_129062092	0.158	NM_001142685	ARHGAP32	Rho GTPase activating protein 32
chr7_-_91794589	0.157	NM_001161528	LRRD1	leucine-rich repeats and death domain containing 1
chr1_+_199996729	0.157	NM_003822 NM_205860	NR5A2	nuclear receptor subfamily 5, group A, member 2
chr2_+_54683276	0.157	NM_003128	SPTBN1	spectrin, beta, non-erythrocytic 1
chr12_+_56522043	0.156		ESYT1	extended synaptotagmin-like protein 1
chr4_+_39063851	0.155	NM_015990 NM_199039	KLHL5	kelch-like 5 (Drosophila)
chr2_-_128100673	0.155	NM_006609	MAP3K2	mitogen-activated protein kinase kinase kinase 2
chr19_-_893215	0.154	NM_005481	MED16	mediator complex subunit 16
chr22_+_31478845	0.154	NM_001207017	SMTN	smoothelin
chr12_-_29937691	0.154	NM_175861	TMTC1	transmembrane and tetratricopeptide repeat containing 1
chr2_+_109204777	0.154		LIMS1	LIM and senescent cell antigen-like domains 1
chr17_+_40996596	0.153	NM_001158 NM_009590	AOC2	amine oxidase, copper containing 2 (retina-specific)

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
156.61	3.35e-04	GO:0006968	cellular defense response
17.39	9.38e-04	GO:0006952	defense response
6.07	2.40e-02	GO:0006950	response to stress

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
44.69	2.66e-03	GO:0005529	sugar binding