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• Activity deltas table
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Motif ID: JUN.p2

Z-value: 2.003

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr19_+_45971249	11.992	NM_001114171 NM_006732	FOSB	FBJ murine osteosarcoma viral oncogene homolog B
chr11_-_1593149	8.589	NM_004420	DUSP8	dual specificity phosphatase 8
chr5_-_172198160	6.612	NM_004417	DUSP1	dual specificity phosphatase 1
chr19_+_49375677	6.298		PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr19_+_49375638	6.142	NM_014330	PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr19_+_49375679	6.120		PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr7_+_28448970	5.745		LOC401317	uncharacterized LOC401317
chr8_-_95274540	4.962	NM_005261 NM_181702	GEM	GTP binding protein overexpressed in skeletal muscle
chr6_-_91006580	4.874	NM_001170794	BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr1_+_212782103	4.722		ATF3	activating transcription factor 3
chr12_-_123380682	4.627	NM_024667	VPS37B	vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr22_+_38597938	4.560	NM_001161572 NM_001161574 NM_012323	MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr6_-_91006460	4.526	NM_021813	BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr12_-_123380608	4.513
chr4_+_75480628	4.412	NM_001657	AREG	amphiregulin
chr8_-_95274520	4.092		GEM	GTP binding protein overexpressed in skeletal muscle
chr12_-_123380628	3.948		VPS37B	vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr6_+_139456240	3.892	NM_016217	HECA	headcase homolog (Drosophila)
chr19_+_45504686	3.890	NM_006509	RELB	v-rel reticuloendotheliosis viral oncogene homolog B
chr22_+_38598065	3.804		MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr8_+_128806720	3.659		PVT1	Pvt1 oncogene (non-protein coding)
chr1_-_59249687	3.522	NM_002228	JUN	jun proto-oncogene
chr19_+_11649578	3.426	NM_001299	CNN1	calponin 1, basic, smooth muscle
chr6_+_135818938	3.402		LINC00271	long intergenic non-protein coding RNA 271
chr2_+_28615695	3.382		FOSL2	FOS-like antigen 2
chr2_+_28615668	3.337		FOSL2	FOS-like antigen 2
chr2_+_28615771	3.291	NM_005253	FOSL2	FOS-like antigen 2
chr7_+_128312345	3.287	NM_001012454 NM_001128926	FAM71F2	family with sequence similarity 71, member F2
chr7_-_100808832	3.181	NM_003378	VGF	VGF nerve growth factor inducible
chr3_+_156544075	3.089	NM_001004316 NM_001193283	LEKR1	leucine, glutamate and lysine rich 1
chr1_+_212738675	3.053	NM_001030287	ATF3	activating transcription factor 3
chr1_-_713985	2.900		LOC100288069	general transcription factor IIi pseudogene
chr21_-_43430448	2.775	NM_001098402 NM_001098403 NM_020727	ZNF295	zinc finger protein 295
chr2_+_220408742	2.435	NM_001005209	TMEM198	transmembrane protein 198
chr14_+_23352430	2.262	NM_173527	REM2	RAS (RAD and GEM)-like GTP binding 2
chr1_-_221915393	2.261		DUSP10	dual specificity phosphatase 10
chr7_+_28725597	2.225	NM_001011666	CREB5	cAMP responsive element binding protein 5
chr10_-_3827418	2.188	NM_001160124 NM_001160125 NM_001300	KLF6	Kruppel-like factor 6
chr1_-_221915426	2.183		DUSP10	dual specificity phosphatase 10
chr1_-_221915458	2.080	NM_007207 NM_144729	DUSP10	dual specificity phosphatase 10
chr1_+_32827797	2.074	NM_052841	TSSK3	testis-specific serine kinase 3
chr1_+_212781969	2.063	NM_001040619 NM_001206484 NM_001206488 NM_001674	ATF3	activating transcription factor 3
chr3_-_8543327	2.055		LOC100288428	uncharacterized LOC100288428
chr20_+_34203746	2.054	NM_003116	SPAG4	sperm associated antigen 4
chr12_-_12715244	2.033	NM_030640	DUSP16	dual specificity phosphatase 16
chr3_-_50374875	2.029	NM_170713	RASSF1	Ras association (RalGDS/AF-6) domain family member 1
chr10_-_3827205	2.027		KLF6	Kruppel-like factor 6
chr5_-_57755787	2.018	NM_001252226 NM_006622	PLK2	polo-like kinase 2
chr9_+_130860769	2.015		SLC25A25	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chrX_+_133941204	2.004	NM_001170782 NM_001170784 NM_001170779 NM_001170781 NM_001170783 NM_138819	FAM122C	family with sequence similarity 122C
chr2_+_149632772	2.001	NM_004522	KIF5C	kinesin family member 5C
chr18_+_23806385	1.916	NM_005640	TAF4B	TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr19_-_460995	1.900	NM_012435	SHC2	SHC (Src homology 2 domain containing) transforming protein 2
chr3_+_141087298	1.881		ZBTB38	zinc finger and BTB domain containing 38
chr2_+_149632836	1.879		KIF5C	kinesin family member 5C
chr3_+_50297644	1.877
chr10_+_134210691	1.874	NM_001098637 NM_138499	PWWP2B	PWWP domain containing 2B
chr1_+_203274646	1.849	NM_006763	BTG2	BTG family, member 2
chr19_-_47734215	1.843	NM_014417	BBC3	BCL2 binding component 3
chr11_+_73087396	1.841	NM_152222	RELT	RELT tumor necrosis factor receptor
chr20_-_44600939	1.820		ZNF335	zinc finger protein 335
chr9_+_34179047	1.814		UBAP1	ubiquitin associated protein 1
chr10_+_104154228	1.775	NM_001077493 NM_001077494	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr22_+_21771661	1.758	NM_015094	HIC2	hypermethylated in cancer 2
chr9_+_102584136	1.748	NM_006981 NM_173199 NM_173200	NR4A3	nuclear receptor subfamily 4, group A, member 3
chr19_+_13263890	1.738		IER2	immediate early response 2
chr1_-_16482426	1.730	NM_004431	EPHA2	EPH receptor A2
chr12_-_132628841	1.701	NM_175066	DDX51	DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr2_-_172967627	1.686		DLX2	distal-less homeobox 2
chr1_+_16010816	1.682	NM_015164	PLEKHM2	pleckstrin homology domain containing, family M (with RUN domain) member 2
chr8_-_144623611	1.674	NM_015117	ZC3H3	zinc finger CCCH-type containing 3
chr8_-_144623579	1.673		ZC3H3	zinc finger CCCH-type containing 3
chr14_+_103995535	1.660		TRMT61A	tRNA methyltransferase 61 homolog A (S. cerevisiae)
chr3_-_50374795	1.635		RASSF1	Ras association (RalGDS/AF-6) domain family member 1
chr5_-_178054072	1.635		CLK4	CDC-like kinase 4
chr5_-_178054089	1.601		CLK4	CDC-like kinase 4
chr19_-_55628780	1.580	NM_017607	PPP1R12C	protein phosphatase 1, regulatory subunit 12C
chr4_+_108745718	1.567	NM_001136258	SGMS2	sphingomyelin synthase 2
chr17_+_27071008	1.564	NM_004295	TRAF4	TNF receptor-associated factor 4
chr2_+_220144024	1.549	NM_001039550 NM_006736	DNAJB2	DnaJ (Hsp40) homolog, subfamily B, member 2
chr3_-_99594915	1.535	NM_014890	FILIP1L	filamin A interacting protein 1-like
chr1_-_193155723	1.528	NM_003783	B3GALT2	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr3_-_156877882	1.522		CCNL1	cyclin L1
chr1_+_16010838	1.516		PLEKHM2	pleckstrin homology domain containing, family M (with RUN domain) member 2
chr8_-_29207795	1.512	NM_001394	DUSP4	dual specificity phosphatase 4
chr14_+_103995473	1.511	NM_152307	TRMT61A	tRNA methyltransferase 61 homolog A (S. cerevisiae)
chr12_-_49504612	1.509		LMBR1L	limb region 1 homolog (mouse)-like
chr9_+_130860816	1.509	NM_052901 NM_001006643	SLC25A25	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr11_+_64692052	1.506	NM_006244	PPP2R5B	protein phosphatase 2, regulatory subunit B', beta
chr10_-_64576074	1.505		EGR2	early growth response 2
chr6_+_89791510	1.483		PNRC1	proline-rich nuclear receptor coactivator 1
chr10_-_64576123	1.483	NM_000399 NM_001136177 NM_001136179	EGR2	early growth response 2
chr15_-_60884615	1.464	NM_134262	RORA	RAR-related orphan receptor A
chr9_-_99382073	1.461	NM_003671 NM_033331	CDC14B	CDC14 cell division cycle 14 homolog B (S. cerevisiae)
chr1_+_45266035	1.448	NM_004073	PLK3	polo-like kinase 3
chr6_-_135818786	1.444		AHI1	Abelson helper integration site 1
chr3_-_187463474	1.433	NM_001706	BCL6	B-cell CLL/lymphoma 6
chr19_-_18392048	1.432		JUND	jun D proto-oncogene
chr14_+_67999915	1.428	NM_020715	PLEKHH1	pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr5_-_64777703	1.425	NM_197941	ADAMTS6	ADAM metallopeptidase with thrombospondin type 1 motif, 6
chr19_-_48614013	1.414	NM_001159322 NM_001159323 NM_003706	PLA2G4C	phospholipase A2, group IVC (cytosolic, calcium-independent)
chr10_+_99079017	1.408	NM_005479	FRAT1	frequently rearranged in advanced T-cell lymphomas
chr7_-_45128492	1.399	NM_001146334	NACAD	NAC alpha domain containing
chr16_+_29912146	1.398	NM_181718	ASPHD1	aspartate beta-hydroxylase domain containing 1
chr20_-_44600787	1.389	NM_022095	ZNF335	zinc finger protein 335
chr17_+_4802866	1.384	NM_001145536	C17orf107	chromosome 17 open reading frame 107
chr11_+_62475113	1.378	NM_012202	GNG3	guanine nucleotide binding protein (G protein), gamma 3
chr4_-_2010961	1.374	NM_005663	WHSC2	Wolf-Hirschhorn syndrome candidate 2
chr7_+_112090463	1.372	NM_001550	IFRD1	interferon-related developmental regulator 1
chr9_+_139221931	1.359	NM_001145638 NM_015597	GPSM1	G-protein signaling modulator 1
chr3_-_133614296	1.359		RAB6B	RAB6B, member RAS oncogene family
chr19_-_42759279	1.357	NM_006494	ERF	Ets2 repressor factor
chr9_-_34397786	1.347	NM_032596	C9orf24	chromosome 9 open reading frame 24
chr19_-_51014344	1.340	NM_138334	JOSD2	Josephin domain containing 2
chr15_+_78556901	1.330	NM_001130182	DNAJA4	DnaJ (Hsp40) homolog, subfamily A, member 4
chr19_-_59066372	1.319		CHMP2A	charged multivesicular body protein 2A
chr2_+_43864405	1.317		PLEKHH2	pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr4_+_119512890	1.300		LOC729218	uncharacterized LOC729218
chr12_-_57914287	1.293	NM_001195053 NM_001195054 NM_001195055 NM_001195056 NM_001195057 NM_004083	DDIT3	DNA-damage-inducible transcript 3
chr5_+_137673223	1.285	NM_001135647	FAM53C	family with sequence similarity 53, member C
chr10_-_31320772	1.283	NM_001143766 NM_001143767 NM_001143768 NM_001143770 NM_001143771 NM_182755	ZNF438	zinc finger protein 438
chr8_+_56686179	1.277
chr19_-_18392436	1.258		JUND	jun D proto-oncogene
chr10_+_5566923	1.255	NM_005185	CALML3	calmodulin-like 3
chr2_+_228678556	1.251	NM_001130046 NM_004591	CCL20	chemokine (C-C motif) ligand 20
chr5_+_137801166	1.251		EGR1	early growth response 1
chr2_+_43864433	1.248	NM_172069	PLEKHH2	pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr2_-_86850935	1.246		RNF103	ring finger protein 103
chr12_+_132628978	1.239	NM_024078	NOC4L	nucleolar complex associated 4 homolog (S. cerevisiae)
chr17_-_8055684	1.232	NM_002616	PER1	period homolog 1 (Drosophila)
chr19_-_18392413	1.224	NM_005354	JUND	jun D proto-oncogene
chr3_+_158288952	1.218	NM_001130156 NM_001130157 NM_001195432 NM_001195433 NM_001195434 NM_022443	MLF1	myeloid leukemia factor 1
chr17_-_8059637	1.215		PER1	period homolog 1 (Drosophila)
chr15_-_80215663	1.209	NM_001100880 NM_001199757	ST20	suppressor of tumorigenicity 20
chr4_+_88571453	1.208	NM_001079911 NM_004407	DMP1	dentin matrix acidic phosphoprotein 1
chr12_-_49504646	1.206	NM_018113	LMBR1L	limb region 1 homolog (mouse)-like
chr9_-_33402505	1.199	NM_001170	AQP7	aquaporin 7
chr2_+_149633173	1.194
chr3_-_50374749	1.194		RASSF1	Ras association (RalGDS/AF-6) domain family member 1
chr17_-_13505217	1.192	NM_006042	HS3ST3A1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr7_-_140624280	1.185	NM_004333	BRAF	v-raf murine sarcoma viral oncogene homolog B1
chr20_+_32254303	1.182	NM_001024675	ACTL10	actin-like 10
chr3_-_47933997	1.181		MAP4	microtubule-associated protein 4
chr16_-_54320367	1.172	NM_024336	IRX3	iroquois homeobox 3
chr6_+_31783280	1.171	NM_005345	HSPA1A	heat shock 70kDa protein 1A
chr9_+_130830447	1.168	NM_001006641	SLC25A25	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr2_+_37571752	1.168	NM_012413	QPCT	glutaminyl-peptide cyclotransferase
chr9_+_130830595	1.166		SLC25A25	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr19_+_55795766	1.165		BRSK1	BR serine/threonine kinase 1
chr19_+_13858687	1.164	NM_030818	CCDC130	coiled-coil domain containing 130
chr5_+_137801178	1.162	NM_001964	EGR1	early growth response 1
chr6_-_88411872	1.159		AKIRIN2	akirin 2
chr11_+_111749947	1.157	NM_022761	C11orf1	chromosome 11 open reading frame 1
chr4_-_89618928	1.154	NM_153757	NAP1L5	nucleosome assembly protein 1-like 5
chr5_-_175964824	1.153		RNF44	ring finger protein 44
chr7_+_20370324	1.153		ITGB8	integrin, beta 8
chr11_+_66610882	1.153	NM_001032279 NM_005133	RCE1	RCE1 homolog, prenyl protein protease (S. cerevisiae)
chr5_-_16617085	1.150	NM_001034850	FAM134B	family with sequence similarity 134, member B
chr3_-_133614421	1.150	NM_016577	RAB6B	RAB6B, member RAS oncogene family
chr4_+_103422479	1.148	NM_001165412 NM_003998	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr9_+_35490018	1.146		RUSC2	RUN and SH3 domain containing 2
chr18_+_77439798	1.137	NM_004715 NM_048368	CTDP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr2_+_70142236	1.136		MXD1	MAX dimerization protein 1
chr7_+_123295860	1.136	NM_207163	LMOD2	leiomodin 2 (cardiac)
chr11_+_18343794	1.135	NM_001142307 NM_005316	GTF2H1	general transcription factor IIH, polypeptide 1, 62kDa
chr9_+_12693385	1.131	NM_000550	TYRP1	tyrosinase-related protein 1
chr1_+_45266048	1.130		PLK3	polo-like kinase 3
chr4_-_103422436	1.128
chr21_+_47546427	1.127		COL6A2	collagen, type VI, alpha 2
chr2_-_86850959	1.126	NM_001198951 NM_001198952 NM_005667	RNF103	ring finger protein 103
chr17_-_62833264	1.122		PLEKHM1P	pleckstrin homology domain containing, family M (with RUN domain) member 1 pseudogene
chr17_-_8151373	1.119	NM_025099	CTC1	CTS telomere maintenance complex component 1
chr3_+_150125983	1.116		TSC22D2	TSC22 domain family, member 2
chr8_-_101322245	1.106	NM_183419	RNF19A	ring finger protein 19A
chr4_-_2010685	1.097		WHSC2	Wolf-Hirschhorn syndrome candidate 2
chr6_+_31783314	1.097		HSPA1A HSPA1B	heat shock 70kDa protein 1A heat shock 70kDa protein 1B
chr2_+_33172368	1.096	NM_206943	LTBP1	latent transforming growth factor beta binding protein 1
chr13_+_97928196	1.094		MBNL2	muscleblind-like 2 (Drosophila)
chr11_+_62475165	1.087		GNG3	guanine nucleotide binding protein (G protein), gamma 3
chr19_-_42759151	1.073		ERF	Ets2 repressor factor
chr17_-_8151353	1.058		CTC1	CTS telomere maintenance complex component 1
chr5_-_54468833	1.058	NM_001145734 NM_001170402 NM_152623	CDC20B	cell division cycle 20 homolog B (S. cerevisiae)
chr1_+_157963310	1.057		KIRREL	kin of IRRE like (Drosophila)
chr10_-_18940515	1.057	NM_182543	NSUN6	NOP2/Sun domain family, member 6
chr5_-_145483877	1.056	NM_001029869	PLAC8L1	PLAC8-like 1
chr11_-_69519105	1.053	NM_005117	FGF19	fibroblast growth factor 19
chr18_+_77439843	1.048		CTDP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr17_+_42385780	1.042	NM_001144825 NM_001144826 NM_006695	RUNDC3A	RUN domain containing 3A
chr2_+_10186284	1.041
chrX_-_52987610	1.040	NM_001242491	FAM156A FAM156B	family with sequence similarity 156, member A family with sequence similarity 156, member B
chr9_+_35489989	1.040	NM_014806	RUSC2	RUN and SH3 domain containing 2
chr4_-_2010702	1.039		WHSC2	Wolf-Hirschhorn syndrome candidate 2
chrX_+_84498993	1.036	NM_021998	ZNF711	zinc finger protein 711
chr5_-_178054001	1.034	NM_020666	CLK4	CDC-like kinase 4
chr21_-_44846927	1.030	NM_173354	SIK1	salt-inducible kinase 1
chr1_-_1284755	1.028		DVL1	dishevelled, dsh homolog 1 (Drosophila)
chr17_-_43568081	1.024		PLEKHM1	pleckstrin homology domain containing, family M (with RUN domain) member 1
chr10_+_63808968	1.020	NM_001244638	ARID5B	AT rich interactive domain 5B (MRF1-like)
chr6_-_88411948	1.018		AKIRIN2	akirin 2
chr16_-_88772732	1.005	NM_001171815	RNF166	ring finger protein 166

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
2.08	9.37e-06	GO:0080090	regulation of primary metabolic process
2.05	1.52e-05	GO:0031323	regulation of cellular metabolic process
2.07	3.76e-05	GO:0060255	regulation of macromolecule metabolic process
1.90	1.57e-04	GO:0019222	regulation of metabolic process
2.27	4.37e-04	GO:0051252	regulation of RNA metabolic process
3.31	6.28e-04	GO:0006351	transcription, DNA-dependent
23.89	1.01e-03	GO:0000188	inactivation of MAPK activity
2.08	1.27e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.02	2.70e-03	GO:0051171	regulation of nitrogen compound metabolic process
2.98	3.20e-03	GO:0032774	RNA biosynthetic process
2.03	3.33e-03	GO:0031326	regulation of cellular biosynthetic process
2.01	4.37e-03	GO:0009889	regulation of biosynthetic process
1.48	5.04e-03	GO:0050794	regulation of cellular process
2.01	7.85e-03	GO:0010468	regulation of gene expression
2.10	1.06e-02	GO:0006355	regulation of transcription, DNA-dependent
1.95	1.14e-02	GO:0048518	positive regulation of biological process
1.66	1.39e-02	GO:0044260	cellular macromolecule metabolic process
2.01	1.45e-02	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.99	1.74e-02	GO:0048522	positive regulation of cellular process
3.09	1.75e-02	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.96	2.53e-02	GO:0010556	regulation of macromolecule biosynthetic process
1.42	2.54e-02	GO:0050789	regulation of biological process
3.00	2.56e-02	GO:0051173	positive regulation of nitrogen compound metabolic process
6.91	3.90e-02	GO:0006470	protein dephosphorylation
2.69	3.93e-02	GO:0006357	regulation of transcription from RNA polymerase II promoter
11.50	4.05e-02	GO:0043407	negative regulation of MAP kinase activity
2.51	4.11e-02	GO:0010604	positive regulation of macromolecule metabolic process
2.17	4.40e-02	GO:0016070	RNA metabolic process
2.42	4.82e-02	GO:0009893	positive regulation of metabolic process

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.54	2.14e-03	GO:0005634	nucleus
1.20	2.32e-02	GO:0005622	intracellular
1.21	2.47e-02	GO:0044424	intracellular part

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
3.48	1.84e-06	GO:0001071	nucleic acid binding transcription factor activity
3.48	1.84e-06	GO:0003700	sequence-specific DNA binding transcription factor activity
47.76	4.23e-06	GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity
44.35	6.54e-06	GO:0033549	MAP kinase phosphatase activity
3.68	9.04e-05	GO:0043565	sequence-specific DNA binding
17.75	1.10e-04	GO:0008138	protein tyrosine/serine/threonine phosphatase activity
2.62	7.18e-03	GO:0030528	transcription regulator activity
1.95	7.67e-03	GO:0003677	DNA binding
7.69	1.45e-02	GO:0004725	protein tyrosine phosphatase activity
5.51	3.17e-02	GO:0004721	phosphoprotein phosphatase activity