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• Activity deltas table
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• Motifs sorted by significance (text)
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Motif ID: LEF1_TCF7_TCF7L1,2.p2

Z-value: 1.591

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr10_+_54074037	1.987	NM_012242	DKK1	dickkopf 1 homolog (Xenopus laevis)
chrX_-_105282714	1.960	NM_000354	SERPINA7	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr14_-_65409445	1.573	NM_002083	GPX2	glutathione peroxidase 2 (gastrointestinal)
chr17_-_10372875	1.432	NM_017533	MYH4	myosin, heavy chain 4, skeletal muscle
chr12_+_70759974	1.354	NM_014505	KCNMB4	potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr8_-_119964059	1.212	NM_002546	TNFRSF11B	tumor necrosis factor receptor superfamily, member 11b
chr2_+_16080639	1.160	NM_005378	MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr4_-_109089444	1.087	NM_001130713 NM_001130714 NM_016269	LEF1	lymphoid enhancer-binding factor 1
chr12_-_122296619	1.086	NM_002150	HPD	4-hydroxyphenylpyruvate dioxygenase
chr20_-_44006876	1.063	NM_014477	TP53TG5	TP53 target 5
chr10_+_115312777	1.040	NM_004132	HABP2	hyaluronan binding protein 2
chr2_-_231989755	0.999	NM_000867	HTR2B	5-hydroxytryptamine (serotonin) receptor 2B
chr2_+_16080559	0.994		MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr3_+_186383770	0.990	NM_000412	HRG	histidine-rich glycoprotein
chr6_+_34216344	0.949
chr15_-_55880508	0.942		PYGO1	pygopus homolog 1 (Drosophila)
chr22_+_24105207	0.934	NM_182520	C22orf15	chromosome 22 open reading frame 15
chr7_-_27213873	0.893	NM_018951	HOXA10	homeobox A10
chrX_+_106163605	0.867	NM_020384	CLDN2	claudin 2
chr7_+_139528951	0.860	NM_001061 NM_001166253 NM_030984	TBXAS1	thromboxane A synthase 1 (platelet)
chr1_-_32801606	0.845	NM_023009	MARCKSL1	MARCKS-like 1
chr7_+_73245192	0.835	NM_001305	CLDN4	claudin 4
chr10_-_91295310	0.823	NM_213606	SLC16A12	solute carrier family 16, member 12 (monocarboxylic acid transporter 12)
chr16_+_72088507	0.820	NM_001126102 NM_005143	HP	haptoglobin
chr10_-_73848766	0.818	NM_001134434 NM_014767	SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr1_+_153330329	0.765	NM_002965	S100A9	S100 calcium binding protein A9
chr4_-_100065372	0.762	NM_000670	ADH4	alcohol dehydrogenase 4 (class II), pi polypeptide
chr2_-_86564632	0.719	NM_001164731 NM_001164732 NM_022912	REEP1	receptor accessory protein 1
chr10_-_5045967	0.698	NM_001135241	AKR1C2	aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chr8_+_120079423	0.689	NM_006438	COLEC10	collectin sub-family member 10 (C-type lectin)
chr13_-_50367027	0.688	NM_002267	KPNA3	karyopherin alpha 3 (importin alpha 4)
chr1_-_11107150	0.678		MASP2	mannan-binding lectin serine peptidase 2
chr16_+_72097124	0.670	NM_020995	HPR	haptoglobin-related protein
chr1_+_200993041	0.664
chr4_-_70626429	0.656	NM_014465	SULT1B1	sulfotransferase family, cytosolic, 1B, member 1
chr5_+_140480056	0.647	NM_018937	PCDHB3	protocadherin beta 3
chr7_+_94292737	0.644		PEG10	paternally expressed 10
chr2_+_172378856	0.641	NM_001127383 NM_024843	CYBRD1	cytochrome b reductase 1
chr1_+_170115187	0.634	NM_001136107	METTL11B	methyltransferase like 11B
chr5_-_135290521	0.629	NM_002302	LECT2	leukocyte cell-derived chemotaxin 2
chr14_-_21572374	0.613
chr7_+_142982039	0.595	NM_001242773 NM_001242774 NM_001242775 NM_001242776 NM_001242777 NM_153345	TMEM139	transmembrane protein 139
chr4_-_103266286	0.582	NM_022154	SLC39A8	solute carrier family 39 (zinc transporter), member 8
chrX_+_12993224	0.577	NM_021109	TMSB4X	thymosin beta 4, X-linked
chr9_+_133971902	0.563		AIF1L	allograft inflammatory factor 1-like
chr22_-_31688329	0.561	NM_001135911 NM_052880	PIK3IP1	phosphoinositide-3-kinase interacting protein 1
chr17_+_7533452	0.557	NM_001040 NM_001146279 NM_001146280 NM_001146281	SHBG	sex hormone-binding globulin
chr1_-_178062734	0.549		LOC100302401	uncharacterized LOC100302401
chr7_+_94292816	0.544		PEG10	paternally expressed 10
chr6_-_24645955	0.544	NM_001168375 NM_001168376 NM_001168374 NM_001168377 NM_014809	KIAA0319	KIAA0319
chr6_+_27114860	0.536	NM_080596	HIST1H2AH	histone cluster 1, H2ah
chr14_-_60097314	0.535		RTN1	reticulon 1
chr20_+_36149606	0.535	NM_005386 NM_181689	NNAT	neuronatin
chr10_-_73848278	0.534		SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr19_+_50084586	0.530	NM_000951	PRRG2	proline rich Gla (G-carboxyglutamic acid) 2
chr2_+_179184970	0.529	NM_145739	OSBPL6	oxysterol binding protein-like 6
chr3_+_46448678	0.522	NM_003965 NM_001130910	CCRL2	chemokine (C-C motif) receptor-like 2
chr11_+_58874614	0.521	NM_001142703 NM_001142704 NM_198947	FAM111B	family with sequence similarity 111, member B
chr10_-_73848530	0.519	NM_001244950	SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr3_-_123339423	0.513	NM_053031 NM_053032	MYLK	myosin light chain kinase
chr8_-_17104266	0.511	NM_013354 NM_054026	CNOT7	CCR4-NOT transcription complex, subunit 7
chr18_+_59992519	0.511	NM_003839	TNFRSF11A	tumor necrosis factor receptor superfamily, member 11a, NFKB activator
chr1_+_100111430	0.511	NM_017734	PALMD	palmdelphin
chr1_+_160160284	0.504	NM_001231	CASQ1	calsequestrin 1 (fast-twitch, skeletal muscle)
chr10_-_93669184	0.504	NM_152429	FGFBP3	fibroblast growth factor binding protein 3
chr19_-_11450254	0.496	NM_004283	RAB3D	RAB3D, member RAS oncogene family
chr13_-_28543423	0.485		CDX2	caudal type homeobox 2
chr18_+_11751470	0.483	NM_001142339 NM_002071	GNAL	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr6_+_96025343	0.483	NM_024641	MANEA	mannosidase, endo-alpha
chr3_-_123339178	0.478		MYLK	myosin light chain kinase
chr12_-_16759939	0.475	NM_001243613	LMO3	LIM domain only 3 (rhombotin-like 2)
chr19_+_35782988	0.472	NM_001199216 NM_002361 NM_080600	MAG	myelin associated glycoprotein
chr1_+_9299902	0.464		H6PD	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr6_-_27440459	0.456	NM_007149	ZNF184	zinc finger protein 184
chr2_-_39348127	0.455		SOS1	son of sevenless homolog 1 (Drosophila)
chr4_-_103265818	0.454		SLC39A8	solute carrier family 39 (zinc transporter), member 8
chr3_-_169487602	0.443	NM_032487	ARPM1	actin related protein M1
chr1_-_53793743	0.443	NM_001018054 NM_004631 NM_017522 NM_033300	LRP8	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr19_-_6502224	0.442	NM_006087	TUBB4A	tubulin, beta 4A class IVa
chr12_+_78225068	0.439	NM_014903	NAV3	neuron navigator 3
chr2_+_27070962	0.432	NM_020134 NM_001253723 NM_001253724	DPYSL5	dihydropyrimidinase-like 5
chr4_-_103266396	0.432	NM_001135147	SLC39A8	solute carrier family 39 (zinc transporter), member 8
chrX_-_73512376	0.431		FTX	FTX transcript, XIST regulator (non-protein coding)
chr14_+_74486049	0.425	NM_025057	C14orf45	chromosome 14 open reading frame 45
chr15_+_50474357	0.424	NM_001159629 NM_003645	SLC27A2	solute carrier family 27 (fatty acid transporter), member 2
chr6_+_167536240	0.423	NM_031409	CCR6	chemokine (C-C motif) receptor 6
chr14_+_85996512	0.419		FLRT2	fibronectin leucine rich transmembrane protein 2
chr11_-_75917450	0.419	NM_004626	WNT11	wingless-type MMTV integration site family, member 11
chr1_-_183559669	0.417	NM_000433 NM_001190789 NM_001190794	NCF2	neutrophil cytosolic factor 2
chr15_+_43809805	0.416	NM_002373	MAP1A	microtubule-associated protein 1A
chr16_+_57702156	0.415	NM_170776	GPR97	G protein-coupled receptor 97
chr3_-_149375584	0.407	NM_001168280 NM_015472	WWTR1	WW domain containing transcription regulator 1
chr11_+_1718424	0.406	NM_001012416	KRTAP5-6	keratin associated protein 5-6
chr6_+_15249034	0.403		JARID2	jumonji, AT rich interactive domain 2
chr8_-_17104103	0.401		CNOT7	CCR4-NOT transcription complex, subunit 7
chrX_-_117119282	0.399	NM_001168299	KLHL13	kelch-like 13 (Drosophila)
chr14_-_21493122	0.399	NM_201538 NM_201539 NM_201540 NM_201541	NDRG2	NDRG family member 2
chr14_-_60097223	0.392		RTN1	reticulon 1
chr1_+_161185084	0.391	NM_004106	FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
chr5_+_140174443	0.391	NM_018905 NM_031495	PCDHA2	protocadherin alpha 2
chr12_+_80603232	0.387	NM_173591	OTOGL	otogelin-like
chr7_+_94024201	0.386		COL1A2	collagen, type I, alpha 2
chr18_-_25756946	0.385		CDH2	cadherin 2, type 1, N-cadherin (neuronal)
chr11_+_56143099	0.383	NM_001005204 NM_001013356	OR8U1 OR8U8	olfactory receptor, family 8, subfamily U, member 1 olfactory receptor, family 8, subfamily U, member 8
chr18_-_46469118	0.383	NM_001190823	SMAD7	SMAD family member 7
chr18_-_25757351	0.381	NM_001792	CDH2	cadherin 2, type 1, N-cadherin (neuronal)
chr6_-_2840683	0.378		SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr5_+_43602738	0.377	NM_012343	NNT	nicotinamide nucleotide transhydrogenase
chr6_+_27925018	0.373	NM_012367	OR2B6	olfactory receptor, family 2, subfamily B, member 6
chr7_-_134143864	0.373	NM_001628	AKR1B1	aldo-keto reductase family 1, member B1 (aldose reductase)
chr1_-_54303933	0.371		TMEM48	transmembrane protein 48
chr2_-_9770999	0.369		YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr7_-_148725500	0.369		PDIA4	protein disulfide isomerase family A, member 4
chr4_-_17806820	0.369		DCAF16	DDB1 and CUL4 associated factor 16
chr6_+_131148544	0.368	NM_001195597	LOC100507203	uncharacterized LOC100507203
chr4_+_113152838	0.368	NM_001128426 NM_018569	AP1AR	adaptor-related protein complex 1 associated regulatory protein
chr3_-_139195300	0.368	NM_004164	RBP2	retinol binding protein 2, cellular
chr7_-_148725764	0.363	NM_004911	PDIA4	protein disulfide isomerase family A, member 4
chr3_-_186262114	0.360	NM_017541	CRYGS	crystallin, gamma S
chr3_-_167813058	0.359		GOLIM4	golgi integral membrane protein 4
chr19_-_17375522	0.359	NM_031941	USHBP1	Usher syndrome 1C binding protein 1
chr1_+_174844655	0.359	NM_001035230	RABGAP1L	RAB GTPase activating protein 1-like
chr17_-_38721701	0.359	NM_001838	CCR7	chemokine (C-C motif) receptor 7
chr5_+_140753480	0.353	NM_018919 NM_032086	PCDHGA6	protocadherin gamma subfamily A, 6
chr3_-_125655881	0.352	NM_001015050 NM_001195223	ALG1L	asparagine-linked glycosylation 1-like
chr14_+_105941061	0.352	NM_001312	CRIP2	cysteine-rich protein 2
chr10_+_25305507	0.352	NM_024838	THNSL1	threonine synthase-like 1 (S. cerevisiae)
chr20_-_44718517	0.350		NCOA5	nuclear receptor coactivator 5
chr10_-_104211244	0.349	NM_024886	C10orf95	chromosome 10 open reading frame 95
chr1_+_168195248	0.348	NM_199344	SFT2D2	SFT2 domain containing 2
chr19_-_48867149	0.346	NM_018273	TMEM143	transmembrane protein 143
chr16_+_2286467	0.346	NM_001374	DNASE1L2	deoxyribonuclease I-like 2
chr1_-_53793583	0.346		LRP8	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr5_+_70944968	0.346		MCCC2	methylcrotonoyl-CoA carboxylase 2 (beta)
chr7_+_94023872	0.345	NM_000089	COL1A2	collagen, type I, alpha 2
chr13_-_72440557	0.343		DACH1	dachshund homolog 1 (Drosophila)
chr2_-_9771101	0.343	NM_006826	YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr15_+_73344824	0.342	NM_001172623 NM_001172624 NM_002499	NEO1	neogenin 1
chr5_-_114515733	0.338	NM_001017397 NM_001017398 NM_018700	TRIM36	tripartite motif containing 36
chr14_+_85996454	0.338	NM_013231	FLRT2	fibronectin leucine rich transmembrane protein 2
chr11_+_76092336	0.335		LOC100506127	putative uncharacterized protein FLJ37770-like
chr1_+_168195257	0.335		SFT2D2	SFT2 domain containing 2
chr1_-_54304107	0.331	NM_001168551 NM_018087	TMEM48	transmembrane protein 48
chr4_+_109543670	0.329		RPL34	ribosomal protein L34
chr8_-_42234562	0.326	NM_014420	DKK4	dickkopf homolog 4 (Xenopus laevis)
chr18_+_11689135	0.325	NM_182978	GNAL	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr7_+_80275967	0.325		CD36	CD36 molecule (thrombospondin receptor)
chr14_-_94443065	0.324	NM_001202429	ASB2	ankyrin repeat and SOCS box containing 2
chr3_-_9921933	0.322	NM_001199551 NM_001199552	CIDEC	cell death-inducing DFFA-like effector c
chrX_-_135962853	0.317
chr1_+_168195241	0.316		SFT2D2	SFT2 domain containing 2
chr5_+_43603312	0.314		NNT	nicotinamide nucleotide transhydrogenase
chr6_-_39072412	0.314		C6orf64	chromosome 6 open reading frame 64
chr2_+_187454987	0.313		ITGAV	integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
chr10_+_102123420	0.312
chr11_-_75921785	0.310		WNT11	wingless-type MMTV integration site family, member 11
chr1_+_63063186	0.310	NM_014495	ANGPTL3	angiopoietin-like 3
chr5_+_140749830	0.309	NM_018924 NM_032097	PCDHGB3	protocadherin gamma subfamily B, 3
chr5_+_43603216	0.308	NM_182977	NNT	nicotinamide nucleotide transhydrogenase
chr20_-_45976626	0.306		ZMYND8	zinc finger, MYND-type containing 8
chr4_+_77953942	0.306		SEPT11	septin 11
chr20_-_656443	0.304
chr10_+_73723992	0.303	NM_004273	CHST3	carbohydrate (chondroitin 6) sulfotransferase 3
chr9_-_35563895	0.303	NM_001099951 NM_001164310	FAM166B	family with sequence similarity 166, member B
chr3_-_148939784	0.301	NM_000096	CP	ceruloplasmin (ferroxidase)
chr1_-_20126368	0.299	NM_181719	TMCO4	transmembrane and coiled-coil domains 4
chr11_-_87908551	0.298	NM_022337	RAB38	RAB38, member RAS oncogene family
chr7_+_63774378	0.298		ZNF736	zinc finger protein 736
chr1_+_82266081	0.296	NM_012302	LPHN2	latrophilin 2
chr2_+_69240137	0.295	NM_018153 NM_032208 NM_053034	ANTXR1	anthrax toxin receptor 1
chrX_-_135962872	0.295		RBMX	RNA binding motif protein, X-linked
chr19_-_3028901	0.294	NM_003260	TLE2	transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr3_+_67048726	0.292	NM_032505	KBTBD8	kelch repeat and BTB (POZ) domain containing 8
chr8_+_29952971	0.292		LEPROTL1	leptin receptor overlapping transcript-like 1
chr16_+_28996146	0.290	NM_001014989	LAT	linker for activation of T cells
chr7_+_23286390	0.290		GPNMB	glycoprotein (transmembrane) nmb
chr5_+_140235594	0.288	NM_018901 NM_031859 NM_031860	PCDHA10	protocadherin alpha 10
chr6_-_151712644	0.288	NM_020861	ZBTB2	zinc finger and BTB domain containing 2
chr1_-_183559463	0.287		NCF2	neutrophil cytosolic factor 2
chr9_-_34376831	0.286	NM_020702	KIAA1161	KIAA1161
chr11_+_5653484	0.284	NM_130390	TRIM34	tripartite motif containing 34
chr15_+_66995414	0.284		SMAD6	SMAD family member 6
chr3_-_184870627	0.282		C3orf70	chromosome 3 open reading frame 70
chr7_+_86974928	0.282	NM_001143935 NM_001243745 NM_021151	CROT	carnitine O-octanoyltransferase
chr20_-_44718564	0.281	NM_020967	NCOA5	nuclear receptor coactivator 5
chr3_-_112359962	0.281	NM_199511 NM_199512	CCDC80	coiled-coil domain containing 80
chr11_-_34535302	0.280	NM_001243080 NM_001422	ELF5	E74-like factor 5 (ets domain transcription factor)
chr19_-_52674895	0.279	NM_001102657	ZNF836	zinc finger protein 836
chr17_-_71088831	0.277		SLC39A11	solute carrier family 39 (metal ion transporter), member 11
chr19_-_46220589	0.276
chr17_-_71088814	0.274		SLC39A11	solute carrier family 39 (metal ion transporter), member 11
chr5_+_43603287	0.272		NNT	nicotinamide nucleotide transhydrogenase
chr10_+_71390002	0.271	NM_145306	C10orf35	chromosome 10 open reading frame 35
chr5_+_133450353	0.270	NM_003202	TCF7	transcription factor 7 (T-cell specific, HMG-box)
chr2_-_211341374	0.270	NM_001136574 NM_006055 NM_001136575	LANCL1	LanC lantibiotic synthetase component C-like 1 (bacterial)
chr17_-_71088832	0.268	NM_001159770 NM_139177	SLC39A11	solute carrier family 39 (metal ion transporter), member 11
chr4_-_79860369	0.267	NM_001040202	PAQR3	progestin and adipoQ receptor family member III
chr3_+_123813527	0.266	NM_001024660 NM_003947	KALRN	kalirin, RhoGEF kinase
chr17_+_67498391	0.266		MAP2K6	mitogen-activated protein kinase kinase 6
chr2_+_38155901	0.266	NM_001170792	FAM82A1	family with sequence similarity 82, member A1

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.