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• Activity deltas table
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Motif ID: MAFB.p2

Z-value: 2.033

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr9_-_110251754	2.300		KLF4	Kruppel-like factor 4 (gut)
chr6_-_91006460	2.043	NM_021813	BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr19_+_11649578	2.028	NM_001299	CNN1	calponin 1, basic, smooth muscle
chr12_-_76425207	1.987		PHLDA1	pleckstrin homology-like domain, family A, member 1
chr3_+_49591897	1.981	NM_003458	BSN	bassoon (presynaptic cytomatrix protein)
chr5_+_137801178	1.930	NM_001964	EGR1	early growth response 1
chr3_-_169482847	1.879		TERC	telomerase RNA component
chr17_-_7518124	1.802	NM_004860	FXR2	fragile X mental retardation, autosomal homolog 2
chr9_-_110251308	1.601		KLF4	Kruppel-like factor 4 (gut)
chrX_+_147582133	1.588	NM_001169122 NM_001169123 NM_001169124 NM_001169125 NM_002025	AFF2	AF4/FMR2 family, member 2
chr19_+_2476122	1.569	NM_015675	GADD45B	growth arrest and DNA-damage-inducible, beta
chr17_+_56065408	1.523
chrX_+_49126480	1.497		PPP1R3F	protein phosphatase 1, regulatory subunit 3F
chr8_-_95274540	1.399	NM_005261 NM_181702	GEM	GTP binding protein overexpressed in skeletal muscle
chr9_+_35560424	1.386		RUSC2	RUN and SH3 domain containing 2
chr7_+_123295860	1.379	NM_207163	LMOD2	leiomodin 2 (cardiac)
chr1_+_63788729	1.379	NM_012183	FOXD3	forkhead box D3
chr6_-_91006580	1.358	NM_001170794	BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2
chrX_+_49126299	1.325	NM_001184745 NM_033215	PPP1R3F	protein phosphatase 1, regulatory subunit 3F
chr16_+_4743709	1.311		NUDT16L1	nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1
chr6_+_89791510	1.302		PNRC1	proline-rich nuclear receptor coactivator 1
chr7_+_28448970	1.296		LOC401317	uncharacterized LOC401317
chr8_-_95274520	1.294		GEM	GTP binding protein overexpressed in skeletal muscle
chr2_+_30369749	1.294	NM_001127399 NM_001127400 NM_001127401 NM_016061	YPEL5	yippee-like 5 (Drosophila)
chr17_+_74261280	1.284	NM_182565	FAM100B	family with sequence similarity 100, member B
chr14_+_75745480	1.266	NM_005252	FOS	FBJ murine osteosarcoma viral oncogene homolog
chr10_-_77161136	1.250		ZNF503	zinc finger protein 503
chr2_-_88926863	1.223	NM_004836	EIF2AK3	eukaryotic translation initiation factor 2-alpha kinase 3
chr16_+_69600110	1.219		NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive
chrX_+_49126326	1.216		PPP1R3F	protein phosphatase 1, regulatory subunit 3F
chr19_+_13263890	1.183		IER2	immediate early response 2
chr19_-_18632857	1.173		ELL	elongation factor RNA polymerase II
chr16_+_4743693	1.167	NM_001193452 NM_032349	NUDT16L1	nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1
chr17_+_74261431	1.161		FAM100B	family with sequence similarity 100, member B
chr1_+_212781969	1.158	NM_001040619 NM_001206484 NM_001206488 NM_001674	ATF3	activating transcription factor 3
chr17_-_72968790	1.153	NM_030630	C17orf28	chromosome 17 open reading frame 28
chr11_-_1593149	1.141	NM_004420	DUSP8	dual specificity phosphatase 8
chr6_+_135818938	1.133		LINC00271	long intergenic non-protein coding RNA 271
chr5_-_107006585	1.129	NM_001962	EFNA5	ephrin-A5
chr2_-_206950895	1.127	NM_017759	INO80D	INO80 complex subunit D
chr2_-_172967014	1.122		DLX2	distal-less homeobox 2
chr5_+_172483285	1.107	NM_001168393 NM_001168394 NM_153607	C5orf41	chromosome 5 open reading frame 41
chr2_+_113033184	1.103		ZC3H6	zinc finger CCCH-type containing 6
chr17_-_72968750	1.102
chr11_+_74459900	1.095	NM_001098638	RNF169	ring finger protein 169
chr2_+_113033146	1.095	NM_198581	ZC3H6	zinc finger CCCH-type containing 6
chr9_-_110252045	1.092	NM_004235	KLF4	Kruppel-like factor 4 (gut)
chr1_-_33430285	1.091	NM_001127361 NM_153341	RNF19B	ring finger protein 19B
chr5_+_137801166	1.090		EGR1	early growth response 1
chr1_+_212782103	1.088		ATF3	activating transcription factor 3
chr12_-_76425375	1.087	NM_007350	PHLDA1	pleckstrin homology-like domain, family A, member 1
chr6_+_157099873	1.077		ARID1B	AT rich interactive domain 1B (SWI1-like)
chr19_-_18632886	1.076	NM_006532	ELL	elongation factor RNA polymerase II
chr10_-_77160650	1.061		ZNF503	zinc finger protein 503
chr13_-_110438896	1.060	NM_003749	IRS2	insulin receptor substrate 2
chr8_-_103667882	1.059	NM_005655	KLF10	Kruppel-like factor 10
chr2_+_30369868	1.054		YPEL5	yippee-like 5 (Drosophila)
chr18_-_35145603	1.049		CELF4	CUGBP, Elav-like family member 4
chr16_-_66959418	1.040	NM_001128850 NM_004165	RRAD	Ras-related associated with diabetes
chr15_-_61521416	1.037		RORA	RAR-related orphan receptor A
chr16_-_54319966	1.027		IRX3	iroquois homeobox 3
chr9_+_102584136	1.022	NM_006981 NM_173199 NM_173200	NR4A3	nuclear receptor subfamily 4, group A, member 3
chr19_+_55795533	1.017	NM_032430	BRSK1	BR serine/threonine kinase 1
chr2_+_30369800	1.015		YPEL5	yippee-like 5 (Drosophila)
chrX_-_153210057	1.015	NM_002910	RENBP	renin binding protein
chr15_-_72612247	0.998	NM_001172684	CELF6	CUGBP, Elav-like family member 6
chr17_-_7517849	0.993		FXR2	fragile X mental retardation, autosomal homolog 2
chr7_+_18548899	0.988	NM_001204147 NM_001204148	HDAC9	histone deacetylase 9
chr10_-_77161424	0.987	NM_032772	ZNF503	zinc finger protein 503
chr13_-_44361032	0.985	NM_001242863 NM_017993	ENOX1	ecto-NOX disulfide-thiol exchanger 1
chr3_-_187463474	0.985	NM_001706	BCL6	B-cell CLL/lymphoma 6
chr10_-_103454687	0.969	NM_022039	FBXW4	F-box and WD repeat domain containing 4
chr19_+_55987698	0.966	NM_033113	ZNF628	zinc finger protein 628
chr2_-_161350304	0.964	NM_002897 NM_016836	RBMS1	RNA binding motif, single stranded interacting protein 1
chr7_-_79082870	0.961	NM_012301	MAGI2	membrane associated guanylate kinase, WW and PDZ domain containing 2
chr11_-_62572827	0.960	NM_001081491 NM_006362	NXF1	nuclear RNA export factor 1
chr22_+_41488607	0.959	NM_001429	EP300	E1A binding protein p300
chr5_+_60628085	0.953	NM_020928	ZSWIM6	zinc finger, SWIM-type containing 6
chr16_-_122573	0.948	NM_022450	RHBDF1	rhomboid 5 homolog 1 (Drosophila)
chr1_-_236030219	0.941	NM_000081	LYST	lysosomal trafficking regulator
chr6_+_43139190	0.940		SRF	serum response factor (c-fos serum response element-binding transcription factor)
chr3_-_187463227	0.937		BCL6	B-cell CLL/lymphoma 6
chr10_+_74451838	0.931	NM_138357	MCU	mitochondrial calcium uniporter
chr15_+_99191671	0.928		IGF1R	insulin-like growth factor 1 receptor
chr15_-_40401041	0.927	NM_001003940	BMF	Bcl2 modifying factor
chr9_+_130854127	0.924	NM_001006642	SLC25A25	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr3_+_9773439	0.920		BRPF1	bromodomain and PHD finger containing, 1
chr16_-_73092533	0.914	NM_001164766	ZFHX3	zinc finger homeobox 3
chr19_-_16738986	0.913	NM_004831	MED26	mediator complex subunit 26
chr4_+_108745718	0.900	NM_001136258	SGMS2	sphingomyelin synthase 2
chr2_+_11295539	0.898	NM_152391	PQLC3	PQ loop repeat containing 3
chr1_+_200842082	0.894	NM_005298	GPR25	G protein-coupled receptor 25
chr5_+_78532338	0.894
chr19_+_56152281	0.893	NM_207115	ZNF580	zinc finger protein 580
chr10_+_77542518	0.892	NM_032024	C10orf11	chromosome 10 open reading frame 11
chr13_+_28712379	0.874	NM_175854	PAN3	PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr7_-_139876718	0.868	NM_030647	JHDM1D	jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae)
chr2_-_172967627	0.864		DLX2	distal-less homeobox 2
chr19_+_45596406	0.863	NM_019121	PPP1R37	protein phosphatase 1, regulatory subunit 37
chr2_-_172967234	0.861	NM_004405	DLX2	distal-less homeobox 2
chr19_-_2151551	0.860	NM_001077523 NM_003938	AP3D1	adaptor-related protein complex 3, delta 1 subunit
chrX_-_103087106	0.860	NM_016370	RAB9B	RAB9B, member RAS oncogene family
chr10_-_3827418	0.859	NM_001160124 NM_001160125 NM_001300	KLF6	Kruppel-like factor 6
chr12_-_112819755	0.858	NM_001109662	C12orf51	chromosome 12 open reading frame 51
chr11_+_61447816	0.857	NM_006133	DAGLA	diacylglycerol lipase, alpha
chr3_+_150125983	0.855		TSC22D2	TSC22 domain family, member 2
chr1_+_45266048	0.853		PLK3	polo-like kinase 3
chr5_+_78531848	0.842	NM_152405	JMY	junction mediating and regulatory protein, p53 cofactor
chr10_+_69644938	0.842	NM_001142498	SIRT1	sirtuin 1
chr15_-_61521478	0.838	NM_134261	RORA	RAR-related orphan receptor A
chr1_-_156470506	0.837	NM_005920	MEF2D	myocyte enhancer factor 2D
chr19_-_18392048	0.837		JUND	jun D proto-oncogene
chr11_+_73087670	0.835	NM_032871	RELT	RELT tumor necrosis factor receptor
chr1_-_156470538	0.830		MEF2D	myocyte enhancer factor 2D
chr16_-_54318889	0.828		IRX3	iroquois homeobox 3
chr1_-_155532152	0.824		ASH1L	ash1 (absent, small, or homeotic)-like (Drosophila)
chr1_+_53099015	0.823	NM_001042693	FAM159A	family with sequence similarity 159, member A
chr6_+_45390284	0.821		RUNX2	runt-related transcription factor 2
chr14_-_27066959	0.818	NM_002515 NM_006489 NM_006491	NOVA1	neuro-oncological ventral antigen 1
chr4_+_75480628	0.817	NM_001657	AREG	amphiregulin
chr10_-_32635842	0.817		EPC1	enhancer of polycomb homolog 1 (Drosophila)
chr1_+_46269283	0.812	NM_015112	MAST2	microtubule associated serine/threonine kinase 2
chr19_-_46285752	0.807	NM_001081560 NM_001081562 NM_004409	DMPK	dystrophia myotonica-protein kinase
chr17_-_42200957	0.806		HDAC5	histone deacetylase 5
chrX_-_154114431	0.805	NM_019863	F8	coagulation factor VIII, procoagulant component
chr1_+_16174358	0.803	NM_015001	SPEN	spen homolog, transcriptional regulator (Drosophila)
chr2_+_189156603	0.803		GULP1	GULP, engulfment adaptor PTB domain containing 1
chr19_-_59069747	0.801		UBE2M	ubiquitin-conjugating enzyme E2M
chr6_+_149721494	0.800	NM_001002255	SUMO4	SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae)
chr19_+_55795766	0.797		BRSK1	BR serine/threonine kinase 1
chr5_-_57755787	0.796	NM_001252226 NM_006622	PLK2	polo-like kinase 2
chr1_+_177140530	0.796	NM_021165	FAM5B	family with sequence similarity 5, member B
chr2_+_189156653	0.793		GULP1	GULP, engulfment adaptor PTB domain containing 1
chr17_-_27332888	0.793	NM_001098635 NM_178860	SEZ6	seizure related 6 homolog (mouse)
chr6_-_111804413	0.791	NM_002912	REV3L	REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
chr5_-_139725860	0.790		HBEGF	heparin-binding EGF-like growth factor
chr14_-_61190458	0.788	NM_017420	SIX4	SIX homeobox 4
chr1_-_156470565	0.787		MEF2D	myocyte enhancer factor 2D
chr17_-_42201009	0.784	NM_001015053 NM_005474	HDAC5	histone deacetylase 5
chr2_-_157189040	0.784	NM_006186	NR4A2	nuclear receptor subfamily 4, group A, member 2
chr19_-_2151534	0.781		AP3D1	adaptor-related protein complex 3, delta 1 subunit
chr7_+_18548963	0.781		HDAC9	histone deacetylase 9
chr1_-_1334648	0.778	NM_001039577 NM_030937	CCNL2	cyclin L2
chr3_-_114343052	0.777	NM_001164347	ZBTB20	zinc finger and BTB domain containing 20
chr4_+_15004297	0.777	NM_001177381 NM_001177382 NM_001177383 NM_001177384 NM_182485 NM_182646	CPEB2	cytoplasmic polyadenylation element binding protein 2
chr12_-_76424474	0.776		PHLDA1	pleckstrin homology-like domain, family A, member 1
chr6_+_12012723	0.775	NM_002114	HIVEP1	human immunodeficiency virus type I enhancer binding protein 1
chr6_-_150039391	0.771	NM_004690	LATS1	LATS, large tumor suppressor, homolog 1 (Drosophila)
chr2_+_198318225	0.768	NM_025147	COQ10B	coenzyme Q10 homolog B (S. cerevisiae)
chr6_+_37787592	0.767		ZFAND3	zinc finger, AN1-type domain 3
chr19_+_49375638	0.764	NM_014330	PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr5_+_173315313	0.758	NM_030627	CPEB4	cytoplasmic polyadenylation element binding protein 4
chr22_-_17602142	0.758	NM_031890 NM_001163079	CECR6	cat eye syndrome chromosome region, candidate 6
chr15_-_40212425	0.758		GPR176	G protein-coupled receptor 176
chr19_+_49375677	0.752		PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr7_+_27135672	0.749		HOTAIRM1	HOXA transcript antisense RNA, myeloid-specific 1 (non-protein coding)
chr10_+_60272868	0.749	NM_001080512	BICC1	bicaudal C homolog 1 (Drosophila)
chr1_-_149908098	0.748	NM_181873	MTMR11	myotubularin related protein 11
chr17_-_18907988	0.743	NM_001039999	FAM83G	family with sequence similarity 83, member G
chr7_-_103629962	0.740	NM_005045 NM_173054	RELN	reelin
chr19_+_45596159	0.735		PPP1R37	protein phosphatase 1, regulatory subunit 37
chr22_+_31489343	0.733		SMTN	smoothelin
chr1_-_155532562	0.730		ASH1L	ash1 (absent, small, or homeotic)-like (Drosophila)
chr9_-_80646150	0.728	NM_002072	GNAQ	guanine nucleotide binding protein (G protein), q polypeptide
chr4_-_74124456	0.724	NM_032217 NM_198889	ANKRD17	ankyrin repeat domain 17
chr4_-_89618928	0.723	NM_153757	NAP1L5	nucleosome assembly protein 1-like 5
chr15_-_65360297	0.716	NM_016563	RASL12	RAS-like, family 12
chr19_+_4791757	0.715		FEM1A	fem-1 homolog a (C. elegans)
chr10_+_69644708	0.712		SIRT1	sirtuin 1
chr7_-_100808832	0.712	NM_003378	VGF	VGF nerve growth factor inducible
chr19_+_49375679	0.711		PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr5_-_11904127	0.710		CTNND2	catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr8_-_8239188	0.709	NM_001080826	SGK223	homolog of rat pragma of Rnd2
chr7_+_128312345	0.706	NM_001012454 NM_001128926	FAM71F2	family with sequence similarity 71, member F2
chr3_-_114102488	0.703	NM_001164342	ZBTB20	zinc finger and BTB domain containing 20
chr19_+_12902295	0.702	NM_002229	JUNB	jun B proto-oncogene
chr7_+_138145179	0.700		TRIM24	tripartite motif containing 24
chr16_+_69599869	0.698		NFAT5	nuclear factor of activated T-cells 5, tonicity-responsive
chr3_+_9773427	0.698	NM_001003694 NM_004634	BRPF1	bromodomain and PHD finger containing, 1
chr19_+_13135368	0.695		NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr19_-_18392436	0.692		JUND	jun D proto-oncogene
chr19_+_13105970	0.691	NM_002501	NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr12_+_50794591	0.689	NM_001170803 NM_001170804 NM_001170808 NM_052879 NM_199188 NM_199190	LARP4	La ribonucleoprotein domain family, member 4
chr6_-_150039159	0.688		LATS1	LATS, large tumor suppressor, homolog 1 (Drosophila)
chr11_+_65837785	0.688	NM_018026	PACS1	phosphofurin acidic cluster sorting protein 1
chr3_-_134093235	0.688	NM_016201	AMOTL2	angiomotin like 2
chr7_-_99756275	0.685	NM_018275	C7orf43	chromosome 7 open reading frame 43
chr4_+_103422553	0.684		NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr3_+_51989329	0.681	NM_080865	GPR62	G protein-coupled receptor 62
chr9_-_3525721	0.678		RFX3	regulatory factor X, 3 (influences HLA class II expression)
chr7_+_64498643	0.677		CCT6P3	chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr1_-_59248287	0.677		JUN	jun proto-oncogene
chr19_-_40724272	0.671	NM_152479	TTC9B	tetratricopeptide repeat domain 9B
chr7_+_6629658	0.670	NM_024067	C7orf26	chromosome 7 open reading frame 26
chr5_+_139060186	0.670		CXXC5	CXXC finger protein 5
chr17_+_59477169	0.666	NM_005994	TBX2	T-box 2
chr12_+_121416548	0.665	NM_000545	HNF1A	HNF1 homeobox A
chr16_+_67282774	0.663	NM_004594	SLC9A5	solute carrier family 9 (sodium/hydrogen exchanger), member 5
chr3_-_50378238	0.661	NM_001206957 NM_007182 NM_170714	RASSF1	Ras association (RalGDS/AF-6) domain family member 1
chr19_-_15560761	0.660	NM_021241	WIZ	widely interspaced zinc finger motifs

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
2.76	6.59e-04	GO:0060255	regulation of macromolecule metabolic process
3.31	9.19e-04	GO:0051252	regulation of RNA metabolic process
2.62	1.58e-03	GO:0080090	regulation of primary metabolic process
2.59	1.98e-03	GO:0031323	regulation of cellular metabolic process
2.46	2.35e-03	GO:0019222	regulation of metabolic process
5.22	3.83e-03	GO:0031328	positive regulation of cellular biosynthetic process
5.88	4.32e-03	GO:0051254	positive regulation of RNA metabolic process
5.13	4.44e-03	GO:0009891	positive regulation of biosynthetic process
2.93	4.84e-03	GO:0010468	regulation of gene expression
4.99	5.61e-03	GO:0006351	transcription, DNA-dependent
2.81	8.64e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.81	8.64e-03	GO:0031326	regulation of cellular biosynthetic process
2.78	1.00e-02	GO:0009889	regulation of biosynthetic process
5.28	1.02e-02	GO:0010557	positive regulation of macromolecule biosynthetic process
2.92	1.03e-02	GO:2000112	regulation of cellular macromolecule biosynthetic process
5.19	1.17e-02	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.73	1.28e-02	GO:0051171	regulation of nitrogen compound metabolic process
4.51	1.36e-02	GO:0032774	RNA biosynthetic process
2.84	1.43e-02	GO:0010556	regulation of macromolecule biosynthetic process
5.04	1.48e-02	GO:0051173	positive regulation of nitrogen compound metabolic process
5.61	1.93e-02	GO:0045893	positive regulation of transcription, DNA-dependent
6.40	2.59e-02	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
5.18	3.38e-02	GO:0010628	positive regulation of gene expression
3.11	3.87e-02	GO:0010467	gene expression

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
5.52	1.57e-05	GO:0001071	nucleic acid binding transcription factor activity
5.52	1.57e-05	GO:0003700	sequence-specific DNA binding transcription factor activity
6.74	2.27e-05	GO:0043565	sequence-specific DNA binding
2.43	4.00e-03	GO:0003676	nucleic acid binding
4.15	6.00e-03	GO:0030528	transcription regulator activity
2.55	3.65e-02	GO:0003677	DNA binding