Motif ID: NR4A2.p2

Z-value: 0.888

Transcription factors associated with NR4A2.p2:

monomer

Gene SymbolEntrez IDGene Name
NR4A2 4929 nuclear receptor subfamily 4, group A, member 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NR4A2hg19_v1_chr2_-_157186681_157186700-0.078.6e-01Click!


Activity profile for motif NR4A2.p2.

activity profile for motif NR4A2.p2


Sorted Z-values histogram for motif NR4A2.p2

Sorted Z-values for motif NR4A2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR4A2.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_72088507 2.028 NM_001126102
NM_005143
HP

haptoglobin

chr16_+_72097124 1.653 NM_020995
HPR
haptoglobin-related protein
chr17_+_7533452 1.270 NM_001040
NM_001146279
NM_001146280
NM_001146281
SHBG



sex hormone-binding globulin



chr6_-_24489738 1.269 NM_177483
NM_001503
GPLD1

glycosylphosphatidylinositol specific phospholipase D1

chr12_-_6484557 1.021 SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr4_+_41614911 1.018 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr19_-_15590203 0.885 NM_052890
PGLYRP2
peptidoglycan recognition protein 2
chr5_-_27038650 0.785 NM_016279
CDH9
cadherin 9, type 2 (T1-cadherin)
chr5_+_133842276 0.782


chr12_-_63544615 0.765 AVPR1A
arginine vasopressin receptor 1A
chrX_-_105282714 0.745 NM_000354
SERPINA7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr3_-_194072004 0.741 NM_001080513
CPN2
carboxypeptidase N, polypeptide 2
chr2_+_120189342 0.735 NM_183240
TMEM37
transmembrane protein 37
chr11_+_116700620 0.717 NM_000040
APOC3
apolipoprotein C-III
chr15_+_43809805 0.709 NM_002373
MAP1A
microtubule-associated protein 1A
chr15_-_75017710 0.702 NM_000499
CYP1A1
cytochrome P450, family 1, subfamily A, polypeptide 1
chr12_+_56075329 0.701 NM_152637
METTL7B
methyltransferase like 7B
chr1_-_190446701 0.686 NM_199051
FAM5C
family with sequence similarity 5, member C
chr12_+_25205180 0.685 NM_001204126
NM_001204127
NM_006152
LRMP


lymphoid-restricted membrane protein


chr1_+_170115187 0.682 NM_001136107
METTL11B
methyltransferase like 11B
chr16_+_58534045 0.658 NM_001242833
NM_001242834
NM_001242835
NM_001242836
NDRG4



NDRG family member 4



chr22_+_35779103 0.650 HMOX1
heme oxygenase (decycling) 1
chr12_+_100750856 0.619 NM_001145288
NM_139319
SLC17A8

solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8

chr12_+_56075418 0.617 METTL7B
methyltransferase like 7B
chr4_-_25032306 0.609 NM_018176
LGI2
leucine-rich repeat LGI family, member 2
chr7_+_73245192 0.592 NM_001305
CLDN4
claudin 4
chrX_+_149613719 0.577 NM_001177466
NM_005491
MAMLD1

mastermind-like domain containing 1

chr11_-_86666211 0.574 NM_012193
FZD4
frizzled family receptor 4
chr8_+_40010986 0.561 NM_020130
C8orf4
chromosome 8 open reading frame 4
chr12_+_78225068 0.560 NM_014903
NAV3
neuron navigator 3
chr1_+_109642814 0.552 SCARNA2
small Cajal body-specific RNA 2
chr15_-_90347173 0.536 ANPEP
alanyl (membrane) aminopeptidase
chr16_+_57728711 0.527 NM_032269
CCDC135
coiled-coil domain containing 135
chr13_+_27844463 0.519 NM_206827
RASL11A
RAS-like, family 11, member A
chrX_+_106163605 0.518 NM_020384
CLDN2
claudin 2
chr10_-_101841593 0.515 NM_001308
CPN1
carboxypeptidase N, polypeptide 1
chr14_-_23288912 0.512 NM_001126106
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr9_+_74764382 0.512 GDA
guanine deaminase
chr12_+_7169192 0.508


chr12_-_6484389 0.499 NM_001159576
SCNN1A
sodium channel, nonvoltage-gated 1 alpha
chr22_+_21128378 0.499 NM_000185
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr9_+_74764417 0.497 GDA
guanine deaminase
chr12_-_70093064 0.493 NM_032735
BEST3
bestrophin 3
chr7_-_92855780 0.491 NM_001039372
HEPACAM2
HEPACAM family member 2
chrX_+_106161589 0.487 NM_001171095
CLDN2
claudin 2
chr15_+_67000929 0.481 NM_001142861
SMAD6
SMAD family member 6
chr3_-_123339178 0.479 MYLK
myosin light chain kinase
chr3_+_186435097 0.478 NM_000893
NM_001102416
NM_001166451
KNG1


kininogen 1


chr11_+_5653484 0.477 NM_130390
TRIM34
tripartite motif containing 34
chr2_-_233877901 0.475 NGEF
neuronal guanine nucleotide exchange factor
chr19_+_589849 0.473 NM_001194
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr2_-_178417434 0.472 NM_152517
TTC30B
tetratricopeptide repeat domain 30B
chr17_-_34328530 0.471 CCL14-CCL15
CCL15
CCL14-CCL15 readthrough
chemokine (C-C motif) ligand 15
chr15_-_90349819 0.470 ANPEP
alanyl (membrane) aminopeptidase
chr2_-_178483372 0.467 TTC30A
tetratricopeptide repeat domain 30A
chr5_-_126409171 0.464 NM_001164478
NM_001164479
C5orf63

chromosome 5 open reading frame 63

chr16_-_58328879 0.462 NM_001080492
PRSS54
protease, serine, 54
chr4_+_41614725 0.460 LIMCH1
LIM and calponin homology domains 1
chr7_+_134212343 0.457 NM_020299
AKR1B10
aldo-keto reductase family 1, member B10 (aldose reductase)
chr8_-_20112691 0.456 NM_021020
LZTS1
leucine zipper, putative tumor suppressor 1
chrX_+_106171328 0.455 CLDN2
claudin 2
chr1_+_9415944 0.451


chr17_+_79679370 0.447 NM_012140
SLC25A10
solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
chr19_-_35992798 0.441 NM_001035516
DMKN
dermokine
chr11_+_63993720 0.440 NM_001128612
NM_001128613
NM_032344
NUDT22


nudix (nucleoside diphosphate linked moiety X)-type motif 22


chr13_-_46756326 0.440 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_+_36690038 0.437 THRAP3
thyroid hormone receptor associated protein 3
chr1_-_144994908 0.437 PDE4DIP
phosphodiesterase 4D interacting protein
chr20_-_62130390 0.437 NM_001958
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr1_-_211752052 0.436 NM_021194
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr7_-_100844192 0.434 NM_178176
MOGAT3
monoacylglycerol O-acyltransferase 3
chr4_+_41614933 0.433 LIMCH1
LIM and calponin homology domains 1
chr1_-_20126368 0.428 NM_181719
TMCO4
transmembrane and coiled-coil domains 4
chr12_-_16759420 0.428 LMO3
LIM domain only 3 (rhombotin-like 2)
chr22_-_30783301 0.426 NM_001017981
RNF215
ring finger protein 215
chr15_+_63050761 0.417 TLN2
talin 2
chr1_-_211751953 0.416 SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr22_-_39240016 0.416 NM_014293
NPTXR
neuronal pentraxin receptor
chr17_-_36104874 0.413 HNF1B
HNF1 homeobox B
chr1_-_205719309 0.412


chr1_-_205719340 0.411 NM_022731
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr17_+_7554711 0.407 ATP1B2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr1_-_211751719 0.403 SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr3_-_123339423 0.393 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr7_-_92848837 0.391 NM_198151
HEPACAM2
HEPACAM family member 2
chr17_+_48046561 0.389 NM_138281
DLX4
distal-less homeobox 4
chr6_+_34216344 0.387


chr9_+_4839763 0.385 RCL1
RNA terminal phosphate cyclase-like 1
chr19_-_11689765 0.384 NM_001111035
NM_001111036
ACP5

acid phosphatase 5, tartrate resistant

chr3_-_124732379 0.384 HEG1
HEG homolog 1 (zebrafish)
chr20_+_19870209 0.380 NM_018993
RIN2
Ras and Rab interactor 2
chr2_-_231084600 0.380 NM_004509
NM_004510
NM_080424
SP110


SP110 nuclear body protein


chr14_+_75894919 0.378 NM_001135048
NM_130469
JDP2

Jun dimerization protein 2

chr19_+_1248548 0.378 NM_177401
MIDN
midnolin
chr1_-_144994839 0.378 PDE4DIP
phosphodiesterase 4D interacting protein
chr1_-_205719273 0.378 NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr1_+_236558715 0.374 NM_080738
EDARADD
EDAR-associated death domain
chr6_-_110679474 0.370 NM_001123364
C6orf186
chromosome 6 open reading frame 186
chr10_+_81107259 0.365 PPIF
peptidylprolyl isomerase F
chr7_-_107443631 0.364 NM_000111
SLC26A3
solute carrier family 26, member 3
chr8_+_125463042 0.363 NM_017956
TRMT12
tRNA methyltransferase 12 homolog (S. cerevisiae)
chr16_+_29789560 0.361 NM_152338
ZG16
zymogen granule protein 16 homolog (rat)
chr1_-_182573393 0.359 NM_002928
RGS16
regulator of G-protein signaling 16
chr7_+_94285676 0.358 NM_001172437
NM_001172438
PEG10

paternally expressed 10

chr1_+_200993041 0.352


chr1_+_87797301 0.351


chr20_+_42187705 0.348 SGK2
serum/glucocorticoid regulated kinase 2
chr9_+_129724503 0.347 NM_001190728
RALGPS1
Ral GEF with PH domain and SH3 binding motif 1
chr3_-_14166370 0.346 NM_001098502
NM_144636
CHCHD4

coiled-coil-helix-coiled-coil-helix domain containing 4

chr17_-_13972715 0.345


chr1_+_81771844 0.345 LPHN2
latrophilin 2
chr14_-_48144156 0.344 NM_001113498
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr17_-_38721701 0.344 NM_001838
CCR7
chemokine (C-C motif) receptor 7
chr10_+_81107242 0.342 PPIF
peptidylprolyl isomerase F
chr3_-_195938256 0.341 NM_001039617
ZDHHC19
zinc finger, DHHC-type containing 19
chr3_-_168865521 0.340 NM_001164000
MECOM
MDS1 and EVI1 complex locus
chr2_-_169887832 0.338 NM_003742
ABCB11
ATP-binding cassette, sub-family B (MDR/TAP), member 11
chr15_-_40630272 0.336 C15orf52
chromosome 15 open reading frame 52
chr1_+_65210724 0.335 NM_018211
RAVER2
ribonucleoprotein, PTB-binding 2
chr1_+_36689996 0.335 NM_005119
THRAP3
thyroid hormone receptor associated protein 3
chrX_-_154299253 0.334 NM_001018024
NM_001018025
MTCP1NB
MTCP1
mature T-cell proliferation 1 neighbor
mature T-cell proliferation 1
chr7_+_94285620 0.331 NM_001040152
NM_001184961
NM_001184962
NM_015068
PEG10



paternally expressed 10



chr6_-_30128688 0.329 NM_006778
NM_052828
TRIM10

tripartite motif containing 10

chr16_+_15489619 0.328 MPV17L
MPV17 mitochondrial membrane protein-like
chr20_+_39969420 0.328 NM_022896
LPIN3
lipin 3
chr11_+_7535000 0.328 NM_003621
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr7_+_73498318 0.327 LIMK1
LIM domain kinase 1
chr12_-_46121489 0.326 LOC400027
uncharacterized LOC400027
chr20_-_39946119 0.325 ZHX3
zinc fingers and homeoboxes 3
chr3_-_11888111 0.324 NM_138807
TAMM41
TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae)
chr3_-_112358510 0.323 CCDC80
coiled-coil domain containing 80
chr19_-_11308184 0.323 NM_001136191
KANK2
KN motif and ankyrin repeat domains 2
chr3_-_50340979 0.323 NM_007312
NM_033159
NM_153282
NM_153283
NM_153285
HYAL1




hyaluronoglucosaminidase 1




chr8_+_99956630 0.320 NM_001142462
NM_053001
OSR2

odd-skipped related 2 (Drosophila)

chr4_+_114214102 0.320 ANK2
ankyrin 2, neuronal
chr1_+_43803474 0.316 NM_005373
MPL
myeloproliferative leukemia virus oncogene
chr6_-_116575170 0.315 NM_021648
TSPYL4
TSPY-like 4
chr1_+_20878931 0.314 NM_207334
FAM43B
family with sequence similarity 43, member B
chr15_+_49170264 0.311 NM_014335
EID1
EP300 interacting inhibitor of differentiation 1
chr19_-_3062191 0.311 NM_001130
NM_198970
AES

amino-terminal enhancer of split

chr10_+_81107228 0.310 PPIF
peptidylprolyl isomerase F
chr16_+_103892 0.310 SNRNP25
small nuclear ribonucleoprotein 25kDa (U11/U12)
chr11_-_116693907 0.309 NM_000482
APOA4
apolipoprotein A-IV
chr6_-_107077167 0.308 NM_032730
RTN4IP1
reticulon 4 interacting protein 1
chr3_+_100328432 0.308 NM_032787
GPR128
G protein-coupled receptor 128
chr17_-_6616651 0.307 NM_001143838
NM_177550
SLC13A5

solute carrier family 13 (sodium-dependent citrate transporter), member 5

chr2_+_112895958 0.307 NM_001128165
NM_153214
FBLN7

fibulin 7

chrX_-_150067062 0.305 CD99L2
CD99 molecule-like 2
chr11_+_61560401 0.305 FEN1
flap structure-specific endonuclease 1
chr12_+_56511969 0.303 NM_032786
ZC3H10
zinc finger CCCH-type containing 10
chr15_-_75932509 0.300 NM_018285
IMP3
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr15_+_75287829 0.300 NM_001178111
NM_001178112
NM_138967
SCAMP5


secretory carrier membrane protein 5


chrX_-_150067127 0.300 NM_001184808
NM_001242614
NM_031462
NM_134445
NM_134446
CD99L2




CD99 molecule-like 2




chr17_-_36105005 0.299 NM_000458
NM_001165923
HNF1B

HNF1 homeobox B

chr19_+_36024313 0.299 NM_014364
GAPDHS
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr15_-_41408409 0.299 INO80
INO80 homolog (S. cerevisiae)
chr3_-_14166292 0.298 CHCHD4
coiled-coil-helix-coiled-coil-helix domain containing 4
chr2_-_233877920 0.297 NM_019850
NGEF
neuronal guanine nucleotide exchange factor
chr20_+_42187634 0.297 NM_170693
SGK2
serum/glucocorticoid regulated kinase 2
chr10_-_21805715 0.296 C10orf140
chromosome 10 open reading frame 140
chr15_+_54305100 0.296 NM_001080534
UNC13C
unc-13 homolog C (C. elegans)
chr6_-_42981656 0.294 MEA1
male-enhanced antigen 1
chr3_-_187009469 0.292 NM_001031849
NM_001879
NM_139125
MASP1


mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)


chr13_-_46756295 0.291 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_-_55266870 0.290 NM_001114108
NM_017904
TTC22

tetratricopeptide repeat domain 22

chr9_+_140145712 0.290 NM_001004353
C9orf173
chromosome 9 open reading frame 173
chr1_-_169555624 0.290 F5
coagulation factor V (proaccelerin, labile factor)
chr9_+_74764266 0.290 NM_001242505
NM_001242506
NM_004293
GDA


guanine deaminase


chr14_-_65409445 0.290 NM_002083
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr3_-_49459870 0.289 AMT
aminomethyltransferase
chr8_+_86376130 0.288 NM_000067
CA2
carbonic anhydrase II
chr1_-_217113007 0.287 NM_001243512
NM_001243513
NM_001243510
NM_001243511
ESRRG



estrogen-related receptor gamma



chr9_+_74764394 0.286 GDA
guanine deaminase
chr16_+_103859 0.286 SNRNP25
small nuclear ribonucleoprotein 25kDa (U11/U12)
chr11_-_111782447 0.286 NM_001885
CRYAB
crystallin, alpha B
chr1_+_178995175 0.285 FAM20B
family with sequence similarity 20, member B
chr2_-_190044330 0.284 NM_000393
COL5A2
collagen, type V, alpha 2
chr10_-_21814610 0.283 NM_207371
C10orf140
chromosome 10 open reading frame 140
chr16_+_19078916 0.282 NM_016138
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr6_+_34206567 0.281 NM_145905
HMGA1
high mobility group AT-hook 1
chr7_-_131241321 0.280 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr10_+_76586299 0.278 NM_012330
KAT6B
K(lysine) acetyltransferase 6B
chr6_-_39693110 0.278 NM_145027
KIF6
kinesin family member 6
chr16_+_103827 0.277 NM_024571
SNRNP25
small nuclear ribonucleoprotein 25kDa (U11/U12)
chr1_+_55107426 0.277 NM_001039464
HEATR8-TTC4
HEATR8
HEATR8-TTC4 readthrough
HEAT repeat containing 8
chr14_+_75894508 0.277 NM_001135047
JDP2
Jun dimerization protein 2
chr17_+_7184978 0.277 NM_001042
SLC2A4
solute carrier family 2 (facilitated glucose transporter), member 4
chr12_+_7167979 0.277 NM_001734
NM_201442
C1S

complement component 1, s subcomponent

chr19_-_6375859 0.276 NM_004158
PSPN
persephin
chr12_-_16760935 0.276 NM_001001395
NM_001243609
LMO3

LIM domain only 3 (rhombotin-like 2)

chr14_+_24458026 0.276 NM_198083
DHRS4L2
dehydrogenase/reductase (SDR family) member 4 like 2
chr11_+_76571966 0.274 ACER3
alkaline ceramidase 3
chr3_-_52931595 0.274 NM_001198974
NM_198563
TMEM110-MUSTN1
TMEM110
TMEM110-MUSTN1 readthrough
transmembrane protein 110
chr6_+_30691151 0.274 TUBB
tubulin, beta class I
chr5_-_112630557 0.274 NM_002387
MCC
mutated in colorectal cancers
chr14_+_95027760 0.274 NM_006215
SERPINA4
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
chrX_-_21776158 0.273 NM_014332
SMPX
small muscle protein, X-linked
chr7_+_94285736 0.270 PEG10
paternally expressed 10
chrX_+_106143393 0.269 NM_001171092
CLDN2
claudin 2
chr1_-_169555710 0.269 NM_000130
F5
coagulation factor V (proaccelerin, labile factor)

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
804.29 2.08e-05 GO:0030492 hemoglobin binding
33.65 1.40e-02 GO:0004252 serine-type endopeptidase activity