Motif ID: PBX1.p2

Z-value: 0.822


Transcription factors associated with PBX1.p2:

Gene SymbolEntrez IDGene Name
PBX1 5087 pre-B-cell leukemia homeobox 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PBX1hg19_v1_chr1_+_164528914_1645290590.078.6e-01Click!


Activity profile for motif PBX1.p2.

activity profile for motif PBX1.p2


Sorted Z-values histogram for motif PBX1.p2

Sorted Z-values for motif PBX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PBX1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr21_+_30517897 0.524 C21orf7
chromosome 21 open reading frame 7
chr2_-_99917638 0.444 NM_174898
LYG1
lysozyme G-like 1
chr19_+_36505409 0.418


chr6_+_26199712 0.403 NM_003522
HIST1H2BF
histone cluster 1, H2bf
chr12_+_21168629 0.395 NM_001009562
SLCO1B7
solute carrier organic anion transporter family, member 1B7 (non-functional)
chr14_+_62462540 0.369 NM_031914
SYT16
synaptotagmin XVI
chr17_+_8191814 0.350 NM_001177801
NM_001177802
NM_016492
RANGRF


RAN guanine nucleotide release factor


chr19_-_41870001 0.332 NM_030578
B9D2
B9 protein domain 2
chr20_-_44563573 0.311 FLJ40606
uncharacterized LOC643549
chr16_+_30907927 0.299 NM_001142544
NM_001330
CTF1

cardiotrophin 1

chr6_+_26045611 0.289 NM_003531
HIST1H3C
histone cluster 1, H3c
chr6_+_149721494 0.286 NM_001002255
SUMO4
SMT3 suppressor of mif two 3 homolog 4 (S. cerevisiae)
chr2_+_200323088 0.276


chr12_-_113658826 0.263 NM_138451
IQCD
IQ motif containing D
chr7_-_138363789 0.243 NM_001139456
SVOPL
SVOP-like
chr7_-_104653471 0.238 LOC100216545
uncharacterized LOC100216545
chr4_-_72649734 0.231 NM_000583
GC
group-specific component (vitamin D binding protein)
chr1_-_35370983 0.225 NM_001080418
DLGAP3
discs, large (Drosophila) homolog-associated protein 3
chr1_-_28241233 0.218 NM_002946
RPA2
replication protein A2, 32kDa
chr15_+_45248902 0.217 NM_152448
C15orf43
chromosome 15 open reading frame 43
chr2_+_12856813 0.208 NM_021643
TRIB2
tribbles homolog 2 (Drosophila)
chr16_+_838634 0.207 CHTF18
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
chr13_-_48612032 0.205 SUCLA2
succinate-CoA ligase, ADP-forming, beta subunit
chr3_+_121554029 0.204 NM_018456
EAF2
ELL associated factor 2
chr8_-_25315746 0.204 KCTD9
potassium channel tetramerisation domain containing 9
chr19_+_14640413 0.203 TECR
trans-2,3-enoyl-CoA reductase
chr6_-_27835308 0.202 NM_005322
HIST1H1B
histone cluster 1, H1b
chr1_-_167487701 0.199 NM_000734
NM_198053
CD247

CD247 molecule

chr7_-_77325539 0.195


chr10_-_102890902 0.195 NM_001085398
TLX1NB
TLX1 neighbor
chr19_+_14640406 0.193 TECR
trans-2,3-enoyl-CoA reductase
chr15_-_37391893 0.191 MEIS2
Meis homeobox 2
chr5_-_89705477 0.185 NM_004365
CETN3
centrin, EF-hand protein, 3
chr1_-_173176314 0.184 NM_003326
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr5_+_140018998 0.176 NM_018502
TMCO6
transmembrane and coiled-coil domains 6
chr15_-_64673569 0.170 NM_001029989
NM_014736
KIAA0101

KIAA0101

chr6_+_26217145 0.169 NM_021052
HIST1H2AE
histone cluster 1, H2ae
chr10_-_21807120 0.168


chr22_-_29137776 0.168 NM_001005735
NM_007194
NM_145862
CHEK2


checkpoint kinase 2


chrX_+_53123211 0.166 LOC100132984
uncharacterized LOC100132984
chr8_-_38008332 0.165 NM_000349
STAR
steroidogenic acute regulatory protein
chr5_-_149535420 0.164 NM_002609
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr12_-_69357019 0.164 NM_001874
CPM
carboxypeptidase M
chr14_+_24584321 0.163 DCAF11
DDB1 and CUL4 associated factor 11
chr4_-_1722978 0.160 NM_001127266
NM_138385
TMEM129

transmembrane protein 129

chr19_+_14640363 0.156 NM_138501
TECR
trans-2,3-enoyl-CoA reductase
chr12_-_15091441 0.156 NM_152321
ERP27
endoplasmic reticulum protein 27
chr5_+_90676131 0.155 LOC100129716
uncharacterized LOC100129716
chr4_+_69681709 0.150 NM_001075
NM_001144767
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr14_+_24584009 0.147 DCAF11
DDB1 and CUL4 associated factor 11
chr14_-_75530716 0.147 NM_001107
NM_203488
ACYP1

acylphosphatase 1, erythrocyte (common) type

chr1_+_117602909 0.145 TTF2
transcription termination factor, RNA polymerase II
chr1_+_151763174 0.142


chr3_+_58484091 0.141 NM_153331
KCTD6
potassium channel tetramerisation domain containing 6
chr3_+_129159150 0.141 IFT122
intraflagellar transport 122 homolog (Chlamydomonas)
chr3_+_111451326 0.135 NM_001134437
PHLDB2
pleckstrin homology-like domain, family B, member 2
chr16_+_838610 0.134 NM_022092
CHTF18
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
chr16_+_838645 0.132 CHTF18
CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae)
chr2_-_190044330 0.132 NM_000393
COL5A2
collagen, type V, alpha 2
chr2_-_193059599 0.130 NM_016192
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chrX_+_71364033 0.126 NM_207422
FLJ44635
TPT1-like protein
chr15_-_37393364 0.125 NM_001220482
NM_002399
MEIS2

Meis homeobox 2

chr5_-_149535138 0.125 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr6_-_87804773 0.125 NM_000735
NM_001252383
CGA

glycoprotein hormones, alpha polypeptide

chr14_+_24583979 0.123 NM_025230
DCAF11
DDB1 and CUL4 associated factor 11
chr5_-_149535309 0.123 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr4_-_174255454 0.122 NM_001130688
NM_002129
HMGB2

high mobility group box 2

chr6_-_68598987 0.115 ERVH-3
endogenous retrovirus group H, member 3
chr5_+_140186658 0.115 NM_018907
NM_031500
PCDHA4

protocadherin alpha 4

chr8_+_99076749 0.115 NM_001170806
NM_173549
C8orf47

chromosome 8 open reading frame 47

chr1_-_28240953 0.114 RPA2
replication protein A2, 32kDa
chr16_-_70323407 0.113 NM_001605
AARS
alanyl-tRNA synthetase
chrX_+_119737743 0.113 NM_014060
MCTS1
malignant T cell amplified sequence 1
chr4_+_86749045 0.112 ARHGAP24
Rho GTPase activating protein 24
chr20_-_44563684 0.111 FLJ40606
uncharacterized LOC643549
chr2_-_219134865 0.109 NM_001087
AAMP
angio-associated, migratory cell protein
chr6_+_31707724 0.108 NM_002441
NM_025259
NM_172165
NM_172166
MSH5-C6orf26
MSH5



MSH5-C6orf26 readthrough (non-protein coding)
mutS homolog 5 (E. coli)



chr6_-_42713783 0.107 TBCC
tubulin folding cofactor C
chr6_+_26124372 0.106 NM_003512
HIST1H2AC
histone cluster 1, H2ac
chr6_+_27114860 0.104 NM_080596
HIST1H2AH
histone cluster 1, H2ah
chr17_-_41977966 0.103 MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr3_-_121553836 0.101 IQCB1
IQ motif containing B1
chr6_-_27775683 0.101 NM_003519
HIST1H2BL
histone cluster 1, H2bl
chr1_-_149783910 0.099 NM_001024599
NM_001161334
HIST2H2BF

histone cluster 2, H2bf

chr17_-_46703613 0.099 NM_024017
HOXB9
homeobox B9
chr10_-_72142344 0.098 NM_018205
NM_018239
LRRC20

leucine rich repeat containing 20

chr8_-_67874824 0.097 NM_001193502
TCF24
transcription factor 24
chrX_-_15353634 0.097 PIGA
phosphatidylinositol glycan anchor biosynthesis, class A
chr6_+_167536240 0.096 NM_031409
CCR6
chemokine (C-C motif) receptor 6
chr19_+_14640403 0.095 TECR
trans-2,3-enoyl-CoA reductase
chr10_+_103986142 0.095 NM_152310
ELOVL3
ELOVL fatty acid elongase 3
chr7_-_7680048 0.095 RPA3
replication protein A3, 14kDa
chr6_-_26199439 0.095 NM_021065
NM_003530
HIST1H2AD
HIST1H3D
histone cluster 1, H2ad
histone cluster 1, H3d
chr3_+_129159075 0.094 IFT122
intraflagellar transport 122 homolog (Chlamydomonas)
chr17_+_1619816 0.094 NM_001163673
NM_152348
WDR81

WD repeat domain 81

chr13_-_46679143 0.093 NM_001872
NM_016413
CPB2

carboxypeptidase B2 (plasma)

chr9_+_34989637 0.093 NM_001135004
NM_012266
DNAJB5

DnaJ (Hsp40) homolog, subfamily B, member 5

chr2_-_219134795 0.092 AAMP
angio-associated, migratory cell protein
chr10_-_45474210 0.092 NM_007021
C10orf10
chromosome 10 open reading frame 10
chr13_+_76194569 0.091 NM_005358
LMO7
LIM domain 7
chr4_-_70080448 0.090 NM_001073
UGT2B11
UGT2B10
UDP glucuronosyltransferase 2 family, polypeptide B11
UDP glucuronosyltransferase 2 family, polypeptide B10
chr16_-_70323343 0.090 AARS
alanyl-tRNA synthetase
chr17_+_46125675 0.090 NM_003204
NFE2L1
nuclear factor (erythroid-derived 2)-like 1
chr18_+_59854514 0.089 NM_020854
KIAA1468
KIAA1468
chr10_+_96522457 0.088 NM_000769
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr6_+_27775898 0.088 NM_003509
HIST1H2AI
HIST1H2AM
HIST1H3F
histone cluster 1, H2ai
histone cluster 1, H2am
histone cluster 1, H3f
chr9_-_116840604 0.088 AMBP
alpha-1-microglobulin/bikunin precursor
chr4_-_84035888 0.088 PLAC8
placenta-specific 8
chr2_-_88427535 0.087 NM_001443
FABP1
fatty acid binding protein 1, liver
chr6_-_30684851 0.086 MDC1
mediator of DNA-damage checkpoint 1
chr11_-_69634191 0.086 NM_005247
FGF3
fibroblast growth factor 3
chr17_+_73663398 0.086 NM_013260
SAP30BP
SAP30 binding protein
chr2_-_219134846 0.085 AAMP
angio-associated, migratory cell protein
chr6_-_31324898 0.085 HLA-B
major histocompatibility complex, class I, B
chr3_+_136581074 0.085 NCK1
NCK adaptor protein 1
chr7_+_107110501 0.085 NM_005295
GPR22
G protein-coupled receptor 22
chr8_+_48873533 0.083 MCM4
minichromosome maintenance complex component 4
chr5_+_176562084 0.082 NSD1
nuclear receptor binding SET domain protein 1
chr5_+_151151660 0.082 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr17_-_73511453 0.081 CASKIN2
CASK interacting protein 2
chr3_-_121553907 0.081 NM_001023570
NM_001023571
IQCB1

IQ motif containing B1

chr2_+_27255823 0.081 TMEM214
transmembrane protein 214
chr14_+_24583905 0.081 NM_001163484
DCAF11
DDB1 and CUL4 associated factor 11
chr3_+_159557649 0.080 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr2_+_113033184 0.079 ZC3H6
zinc finger CCCH-type containing 6
chr16_+_2273558 0.079 NM_004424
E4F1
E4F transcription factor 1
chr3_+_129158949 0.079 NM_018262
NM_052985
NM_052989
NM_052990
IFT122



intraflagellar transport 122 homolog (Chlamydomonas)



chrX_-_10645726 0.078 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr16_+_67927170 0.078 NM_006742
PSKH1
protein serine kinase H1
chr16_+_2273603 0.078 E4F1
E4F transcription factor 1
chr5_-_75013209 0.075 NM_001099271
POC5
POC5 centriolar protein homolog (Chlamydomonas)
chr12_+_28343390 0.074


chr3_+_159557745 0.074 SCHIP1
schwannomin interacting protein 1
chr16_-_1832571 0.074 SPSB3
splA/ryanodine receptor domain and SOCS box containing 3
chr1_-_149859465 0.074 NM_175065
HIST2H2AB
HIST2H2BE
histone cluster 2, H2ab
histone cluster 2, H2be
chr16_+_82068830 0.074 NM_002153
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr3_-_12586962 0.073 NM_001195279
LOC100129480
uncharacterized LOC100129480
chr2_+_168043792 0.073 NM_001199144
NM_001199145
XIRP2

xin actin-binding repeat containing 2

chr19_+_16296211 0.073 NM_014077
FAM32A
family with sequence similarity 32, member A
chr10_+_5238756 0.072 NM_001818
AKR1C4
aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)
chr1_-_38397417 0.072 INPP5B
inositol polyphosphate-5-phosphatase, 75kDa
chr6_-_26271588 0.071 NM_003534
HIST1H3G
histone cluster 1, H3g
chr20_-_45976626 0.071 ZMYND8
zinc finger, MYND-type containing 8
chr14_+_93673583 0.071 UBR7
ubiquitin protein ligase E3 component n-recognin 7 (putative)
chrX_+_52926358 0.070 FAM156B
family with sequence similarity 156, member B
chr6_-_42713822 0.069 TBCC
tubulin folding cofactor C
chr14_+_100150596 0.069 NM_006668
CYP46A1
cytochrome P450, family 46, subfamily A, polypeptide 1
chr17_-_73511626 0.068 NM_020753
CASKIN2
CASK interacting protein 2
chr2_+_176972005 0.068 NM_021192
HOXD11
homeobox D11
chr16_-_58328879 0.067 NM_001080492
PRSS54
protease, serine, 54
chr9_-_116840545 0.067 AMBP
alpha-1-microglobulin/bikunin precursor
chr11_+_34460421 0.065 NM_001752
CAT
catalase
chr2_+_183943511 0.065 DUSP19
dual specificity phosphatase 19
chr9_-_116840460 0.065 AMBP
alpha-1-microglobulin/bikunin precursor
chr4_+_108852671 0.064 NM_183075
CYP2U1
cytochrome P450, family 2, subfamily U, polypeptide 1
chr12_+_121124958 0.064 MLEC
malectin
chr19_+_39881950 0.063 NM_017592
MED29
mediator complex subunit 29
chr12_+_121124922 0.063 NM_014730
MLEC
malectin
chrX_+_52926334 0.063 FAM156A
FAM156B
family with sequence similarity 156, member A
family with sequence similarity 156, member B
chr18_-_47018842 0.062 NM_001199356
NM_000985
NM_001035006
NM_001199340
NM_001199345
RPL17-C18ORF32
RPL17



RPL17-C18orf32 readthrough
ribosomal protein L17



chr11_+_95523809 0.062 CEP57
centrosomal protein 57kDa
chr17_-_73663221 0.062 NM_001003715
NM_001003716
NM_004259
RECQL5


RecQ protein-like 5


chr10_+_102891060 0.061 NM_001195517
NM_005521
TLX1

T-cell leukemia homeobox 1

chr17_-_38821286 0.060 NM_152349
KRT222
keratin 222
chr19_+_54619149 0.060 PRPF31
PRP31 pre-mRNA processing factor 31 homolog (S. cerevisiae)
chr3_+_129159089 0.060 IFT122
intraflagellar transport 122 homolog (Chlamydomonas)
chr15_+_93443418 0.060 NM_001042572
NM_001271
CHD2

chromodomain helicase DNA binding protein 2

chr3_+_52811601 0.060 NM_002215
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr3_-_53164417 0.060 NM_052859
RFT1
RFT1 homolog (S. cerevisiae)
chr14_+_93673628 0.059 UBR7
ubiquitin protein ligase E3 component n-recognin 7 (putative)
chr5_-_27038650 0.059 NM_016279
CDH9
cadherin 9, type 2 (T1-cadherin)
chr9_-_116840551 0.059 AMBP
alpha-1-microglobulin/bikunin precursor
chr16_+_82068910 0.058 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr14_-_36789794 0.058 NM_001144891
NM_016586
MBIP

MAP3K12 binding inhibitory protein 1

chr8_+_18079176 0.057 NM_001160174
NAT1
N-acetyltransferase 1 (arylamine N-acetyltransferase)
chr3_-_32544358 0.057 NM_017801
CMTM6
CKLF-like MARVEL transmembrane domain containing 6
chr1_+_60280462 0.056 NM_015888
HOOK1
hook homolog 1 (Drosophila)
chr20_-_32307889 0.056 NM_007238
NM_183397
PXMP4

peroxisomal membrane protein 4, 24kDa

chrX_+_115567820 0.055 SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr1_-_228645517 0.055 NM_033445
HIST3H2A
histone cluster 3, H2a
chr1_+_151227237 0.055 PSMD4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
chrX_+_119737905 0.055 MCTS1
malignant T cell amplified sequence 1
chr1_+_228645807 0.054 NM_175055
HIST3H2BB
histone cluster 3, H2bb
chr2_+_88472657 0.054 NM_018271
THNSL2
threonine synthase-like 2 (S. cerevisiae)
chr1_+_145438437 0.054 NM_006472
TXNIP
thioredoxin interacting protein
chr16_-_69788798 0.054 NM_014062
NOB1
NIN1/RPN12 binding protein 1 homolog (S. cerevisiae)
chr6_+_35200627 0.054 SCUBE3
signal peptide, CUB domain, EGF-like 3
chr1_+_171060017 0.054 NM_001002294
NM_006894
FMO3

flavin containing monooxygenase 3

chr1_-_115323227 0.054 SIKE1
suppressor of IKBKE 1
chr17_+_46125725 0.054 NFE2L1
nuclear factor (erythroid-derived 2)-like 1
chr15_+_93443559 0.053 CHD2
chromodomain helicase DNA binding protein 2
chr3_+_129159138 0.053 IFT122
intraflagellar transport 122 homolog (Chlamydomonas)
chr5_+_148737569 0.053 NM_024028
PCYOX1L
prenylcysteine oxidase 1 like
chr2_-_27603249 0.052 NM_001201459
ZNF513
zinc finger protein 513
chr17_-_26941178 0.052 NM_001174103
SGK494
uncharacterized serine/threonine-protein kinase SgK494
chr12_-_101603984 0.051 NM_145913
SLC5A8
solute carrier family 5 (iodide transporter), member 8
chr2_-_211341374 0.051 NM_001136574
NM_006055
NM_001136575
LANCL1


LanC lantibiotic synthetase component C-like 1 (bacterial)


chr3_-_32544319 0.050 CMTM6
CKLF-like MARVEL transmembrane domain containing 6
chr19_+_12203077 0.050 ZNF788
zinc finger family member 788
chr16_+_11439311 0.050 RMI2
RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae)

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.