Motif ID: POU3F1..4.p2

Z-value: 0.943


Transcription factors associated with POU3F1..4.p2:

Gene SymbolEntrez IDGene Name
POU3F1 5453 POU class 3 homeobox 1
POU3F2 5454 POU class 3 homeobox 2
POU3F3 5455 POU class 3 homeobox 3
POU3F4 5456 POU class 3 homeobox 4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
POU3F2hg19_v1_chr6_+_99282597_992827480.206.1e-01Click!


Activity profile for motif POU3F1..4.p2.

activity profile for motif POU3F1..4.p2


Sorted Z-values histogram for motif POU3F1..4.p2

Sorted Z-values for motif POU3F1..4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU3F1..4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_371994 0.930 NM_001190997
NM_001243392
NM_016615
SLC6A13


solute carrier family 6 (neurotransmitter transporter, GABA), member 13


chrX_+_65384078 0.824 NM_001130860
NM_014799
HEPH

hephaestin

chr8_-_6420454 0.790 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr1_+_178310605 0.634 NM_004841
RASAL2
RAS protein activator like 2
chr16_+_4845265 0.571 NM_001253793
NM_001253794
LOC440335

uncharacterized LOC440335

chr4_+_87857394 0.562


chr7_+_28338939 0.548 NM_182899
CREB5
cAMP responsive element binding protein 5
chr13_-_60587298 0.497 NM_030932
DIAPH3
diaphanous homolog 3 (Drosophila)
chr1_+_186798031 0.480 NM_024420
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr4_+_187148624 0.467 NM_000892
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr6_-_152702450 0.457 SYNE1
spectrin repeat containing, nuclear envelope 1
chr1_+_171283372 0.433 NM_002022
FMO4
flavin containing monooxygenase 4
chr12_-_10542616 0.426 NM_007360
KLRK1
killer cell lectin-like receptor subfamily K, member 1
chrX_-_48327739 0.417 SLC38A5
solute carrier family 38, member 5
chr15_-_56209305 0.412 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chrX_+_100805415 0.402 NM_016608
ARMCX1
armadillo repeat containing, X-linked 1
chr2_+_228678556 0.402 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr3_+_28431986 0.402 NM_001040432
ZCWPW2
zinc finger, CW type with PWWP domain 2
chr1_-_89641722 0.400 NM_207398
GBP7
guanylate binding protein 7
chr6_-_46889620 0.394 NM_001098518
GPR116
G protein-coupled receptor 116
chr5_+_55149149 0.393 NM_001242636
NM_001242639
IL31RA

interleukin 31 receptor A

chr2_-_197674875 0.383 NM_213608
C2orf66
chromosome 2 open reading frame 66
chr7_-_20256942 0.376 NM_182762
MACC1
metastasis associated in colon cancer 1
chrX_-_124097601 0.369 NM_001163278
NM_001163279
NM_014253
ODZ1


odz, odd Oz/ten-m homolog 1 (Drosophila)


chr12_-_57472573 0.349 NM_001130963
NM_015257
TMEM194A

transmembrane protein 194A

chr6_-_152702329 0.346 SYNE1
spectrin repeat containing, nuclear envelope 1
chr11_-_85469043 0.340 NM_001162951
NM_001162953
SYTL2

synaptotagmin-like 2

chr16_+_15031299 0.324 NM_006985
NPIP
nuclear pore complex interacting protein
chr13_-_60325073 0.317


chr11_+_105480799 0.316 NM_000829
NM_001077243
NM_001077244
GRIA4


glutamate receptor, ionotrophic, AMPA 4


chr2_-_198540583 0.302 NM_144629
RFTN2
raftlin family member 2
chr13_+_97874540 0.296 NM_144778
NM_207304
MBNL2

muscleblind-like 2 (Drosophila)

chr14_-_75330535 0.291 NM_001080408
NM_001243007
PROX2

prospero homeobox 2

chr6_+_24357130 0.286 NM_181337
KAAG1
kidney associated antigen 1
chr13_+_97874704 0.279 MBNL2
muscleblind-like 2 (Drosophila)
chr15_+_78384926 0.267 NM_001101404
SH2D7
SH2 domain containing 7
chr2_-_207082626 0.264 NM_001098199
NM_005279
GPR1

G protein-coupled receptor 1

chr17_-_76732944 0.255


chr7_-_16921596 0.252 NM_176813
AGR3
anterior gradient 3 homolog (Xenopus laevis)
chr6_-_31689455 0.246 NM_025261
LY6G6C
lymphocyte antigen 6 complex, locus G6C
chr12_+_62954275 0.241 MON2
MON2 homolog (S. cerevisiae)
chr6_+_17282931 0.238 NM_153020
RBM24
RNA binding motif protein 24
chr2_-_202222066 0.235 NM_001127391
NM_139163
ALS2CR12

amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12

chr7_+_28475233 0.233 NM_004904
CREB5
cAMP responsive element binding protein 5
chr9_-_4152182 0.227 NM_152629
GLIS3
GLIS family zinc finger 3
chr3_-_160101443 0.223 NM_001190242
IFT80
intraflagellar transport 80 homolog (Chlamydomonas)
chr6_-_139613114 0.221 NM_153235
TXLNB
taxilin beta
chrX_-_73834427 0.218


chr6_+_49467670 0.216 NM_001010904
GLYATL3
glycine-N-acyltransferase-like 3
chr4_-_76957139 0.215 NM_005409
CXCL11
chemokine (C-X-C motif) ligand 11
chr12_+_52056547 0.213 NM_001177984
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr9_-_22009270 0.208 NM_004936
NM_078487
CDKN2B

cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)

chr19_-_10679328 0.206 CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chrX_-_15620191 0.205 NM_021804
ACE2
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr1_+_109255555 0.192 NM_001144937
FNDC7
fibronectin type III domain containing 7
chr17_+_28268622 0.189 NM_198529
EFCAB5
EF-hand calcium binding domain 5
chr11_-_85780899 0.187 NM_001206947
PICALM
phosphatidylinositol binding clathrin assembly protein
chr7_-_87342569 0.185 NM_000927
ABCB1
ATP-binding cassette, sub-family B (MDR/TAP), member 1
chr7_-_132333446 0.183 NM_181775
PLXNA4
plexin A4
chr8_-_124749573 0.181 NM_001003954
NM_004306
ANXA13

annexin A13

chr2_+_143635194 0.180 NM_001032998
NM_001199241
NM_003937
KYNU


kynureninase


chr9_-_111618209 0.176 NM_006686
ACTL7B
actin-like 7B
chr13_-_47470967 0.175 NM_000621
NM_001165947
HTR2A

5-hydroxytryptamine (serotonin) receptor 2A

chr12_-_15865847 0.174 EPS8
epidermal growth factor receptor pathway substrate 8
chr11_-_78052925 0.171 NM_012296
GAB2
GRB2-associated binding protein 2
chr7_-_83278478 0.170 NM_012431
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr3_-_99594915 0.169 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr7_-_124405680 0.166 NM_005302
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr11_-_5323174 0.165 NM_033179
OR51B4
olfactory receptor, family 51, subfamily B, member 4
chr6_+_43738394 0.163 VEGFA
vascular endothelial growth factor A
chr2_+_143635225 0.159 KYNU
kynureninase
chr11_+_5775922 0.158 NM_001005175
OR52N4
olfactory receptor, family 52, subfamily N, member 4
chr1_-_21377387 0.158 EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr6_+_7402879 0.157 NM_153005
RIOK1
RIO kinase 1 (yeast)
chr14_+_32798478 0.156 NM_004274
AKAP6
A kinase (PRKA) anchor protein 6
chr7_-_83270746 0.153 NM_001178129
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr13_-_22178282 0.153 EFHA1
EF-hand domain family, member A1
chr12_-_15815073 0.151 EPS8
epidermal growth factor receptor pathway substrate 8
chr5_-_157002739 0.150 NM_033274
ADAM19
ADAM metallopeptidase domain 19
chr10_+_114043413 0.149 NM_058222
TECTB
tectorin beta
chr1_-_21377452 0.148 EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr2_+_166095911 0.147 NM_001040142
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chrX_-_73834460 0.139 NM_016120
NM_183353
RLIM

ring finger protein, LIM domain interacting

chr12_+_12224401 0.139 NM_030766
NM_138722
BCL2L14

BCL2-like 14 (apoptosis facilitator)

chr1_+_230883129 0.138 NM_006615
NM_016452
CAPN9

calpain 9

chr9_+_5890801 0.137 NM_005511
MLANA
melan-A
chr1_+_157963062 0.136 NM_018240
KIRREL
kin of IRRE like (Drosophila)
chr22_+_21821458 0.136 NM_001207052
TMEM191C
transmembrane protein 191C
chr6_+_28234787 0.133 NM_001023560
NM_001111039
NM_152736
ZNF187


zinc finger protein 187


chr3_+_187943192 0.132 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr5_-_132272803 0.132


chrX_-_73834430 0.130 RLIM
ring finger protein, LIM domain interacting
chr2_+_135596185 0.126 NM_138326
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr14_+_24782312 0.126 NM_181657
LTB4R
leukotriene B4 receptor
chr3_-_114102488 0.125 NM_001164342
ZBTB20
zinc finger and BTB domain containing 20
chr19_+_41305100 0.123 EGLN2
egl nine homolog 2 (C. elegans)
chr1_+_45274153 0.122 NM_001136537
BTBD19
BTB (POZ) domain containing 19
chr11_-_67205151 0.122 NM_005608
PTPRCAP
protein tyrosine phosphatase, receptor type, C-associated protein
chr13_+_99058147 0.120


chr2_-_48115846 0.120 NM_025133
FBXO11
F-box protein 11
chr6_+_26104103 0.118 NM_003542
HIST2H4B
HIST1H4C
histone cluster 2, H4b
histone cluster 1, H4c
chrX_+_129139163 0.116 NM_021946
BCORL1
BCL6 corepressor-like 1
chr16_+_69680959 0.114 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr5_-_157002705 0.113


chr12_+_80603232 0.113 NM_173591
OTOGL
otogelin-like
chr18_+_19353635 0.113 MIB1
mindbomb homolog 1 (Drosophila)
chr3_-_42814734 0.112 NM_144719
CCDC13
coiled-coil domain containing 13
chr11_+_5710926 0.108 TRIM22
tripartite motif containing 22
chr22_-_38881529 0.108 DDX17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr2_+_189156603 0.105 GULP1
GULP, engulfment adaptor PTB domain containing 1
chr3_+_136676706 0.105 NM_144717
IL20RB
interleukin 20 receptor beta
chr16_+_3702939 0.105 NM_005223
DNASE1
deoxyribonuclease I
chr2_+_210444364 0.104 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr3_-_114343052 0.104 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr8_+_76452202 0.102 NM_004133
HNF4G
hepatocyte nuclear factor 4, gamma
chr6_+_43399488 0.101 NM_033450
ABCC10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr17_+_72429835 0.099 NM_018653
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr1_+_104097321 0.098 NM_020978
AMY2B
amylase, alpha 2B (pancreatic)
chr13_+_97928196 0.098 MBNL2
muscleblind-like 2 (Drosophila)
chr17_-_7493389 0.098 NM_006942
SOX15
SRY (sex determining region Y)-box 15
chr1_+_68297985 0.097 LOC100289178
uncharacterized LOC100289178
chr2_-_201936350 0.096 FAM126B
family with sequence similarity 126, member B
chr9_+_92219926 0.096 NM_006705
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr2_+_68872953 0.096 NM_138964
PROKR1
prokineticin receptor 1
chr10_+_95848811 0.096 NM_001165979
PLCE1
phospholipase C, epsilon 1
chr15_+_71184781 0.096 NM_001199017
NM_017691
NM_001199018
LRRC49


leucine rich repeat containing 49


chr12_-_29937691 0.095 NM_175861
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr1_+_174128654 0.095 RABGAP1L
RAB GTPase activating protein 1-like
chr3_+_25469833 0.093 NM_000965
RARB
retinoic acid receptor, beta
chr5_+_149997205 0.093 NM_001166209
SYNPO
synaptopodin
chr5_+_68788118 0.093 NM_002538
OCLN
occludin
chr2_+_108994366 0.091 NM_006588
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr12_-_11244828 0.091 NM_176884
TAS2R43
TAS2R31
taste receptor, type 2, member 43
taste receptor, type 2, member 31
chr7_+_91924291 0.090


chr11_-_64684606 0.090 NM_015104
ATG2A
ATG2 autophagy related 2 homolog A (S. cerevisiae)
chr3_+_188889762 0.089 NM_198485
TPRG1
tumor protein p63 regulated 1
chr17_-_6983503 0.088 NM_006344
NM_182906
CLEC10A

C-type lectin domain family 10, member A

chr6_-_117150197 0.088 NM_148963
GPRC6A
G protein-coupled receptor, family C, group 6, member A
chr6_+_147829784 0.088 NM_001030060
SAMD5
sterile alpha motif domain containing 5
chr18_+_55888838 0.088 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr8_+_26150731 0.087 NM_001177591
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr4_+_102711833 0.086 BANK1
B-cell scaffold protein with ankyrin repeats 1
chr1_+_78470593 0.086 NM_007034
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr5_-_41213513 0.086 NM_000065
C6
complement component 6
chr19_+_41305041 0.085 NM_080732
EGLN2
egl nine homolog 2 (C. elegans)
chr4_-_153303663 0.084 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr8_-_28347733 0.084 NM_172366
FBXO16
ZNF395
F-box protein 16
zinc finger protein 395
chr16_-_56459371 0.083 NM_001144
AMFR
autocrine motility factor receptor
chr13_+_42712177 0.083 NM_001204505
NM_001204506
DGKH

diacylglycerol kinase, eta

chr6_+_33387846 0.082 NM_006772
SYNGAP1
synaptic Ras GTPase activating protein 1
chr18_-_53068755 0.081 TCF4
transcription factor 4
chr2_-_111230651 0.081 NM_001205288
NM_033514
LIMS3-LOC440895
LIMS3L
LIMS3
LIMS3-LOC440895 readthrough
LIM and senescent cell antigen-like domains 3-like
LIM and senescent cell antigen-like domains 3
chr4_+_169418167 0.081 NM_001166108
NM_016081
PALLD

palladin, cytoskeletal associated protein

chr10_+_105127709 0.081 NM_006951
TAF5
TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
chr2_-_201936368 0.080 FAM126B
family with sequence similarity 126, member B
chr10_+_32856650 0.080 NM_024688
C10orf68
chromosome 10 open reading frame 68
chr1_-_162346579 0.080 NM_182581
C1orf111
chromosome 1 open reading frame 111
chr13_-_78493902 0.080 NM_001201397
EDNRB
endothelin receptor type B
chr19_-_10679620 0.080 NM_001800
NM_079421
CDKN2D

cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)

chrX_-_109683457 0.080 NM_001171689
AMMECR1
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr3_+_130569368 0.080 NM_001199180
NM_001199181
NM_001199182
ATP2C1


ATPase, Ca++ transporting, type 2C, member 1


chr11_-_71781091 0.079 NUMA1
nuclear mitotic apparatus protein 1
chr9_-_3223007 0.078


chr11_-_73720281 0.077 NM_003356
NM_022803
UCP3

uncoupling protein 3 (mitochondrial, proton carrier)

chr3_+_12392993 0.077 NM_015869
PPARG
peroxisome proliferator-activated receptor gamma
chr1_-_234743488 0.076 IRF2BP2
interferon regulatory factor 2 binding protein 2
chr9_+_35042222 0.076 NM_001040410
NM_203299
C9orf131

chromosome 9 open reading frame 131

chr11_-_30601919 0.075 NM_001584
MPPED2
metallophosphoesterase domain containing 2
chr3_+_11267666 0.075 NM_001098211
HRH1
histamine receptor H1
chr1_-_169396654 0.074 NM_021179
C1orf114
chromosome 1 open reading frame 114
chr2_+_109223600 0.074 NM_001193482
LIMS1
LIM and senescent cell antigen-like domains 1
chr5_+_141348450 0.074 NM_004290
NM_183398
NM_183400
RNF14


ring finger protein 14


chr4_+_109088677 0.074 LOC641518
uncharacterized LOC641518
chr2_+_189156653 0.074 GULP1
GULP, engulfment adaptor PTB domain containing 1
chr9_+_125795787 0.073 RABGAP1
GPR21
RAB GTPase activating protein 1
G protein-coupled receptor 21
chr9_+_12693385 0.073 NM_000550
TYRP1
tyrosinase-related protein 1
chr1_-_173962050 0.073 NM_172071
RC3H1
ring finger and CCCH-type domains 1
chr9_+_130830447 0.072 NM_001006641
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr12_+_54519836 0.072 LOC400043
uncharacterized LOC400043
chr9_+_79968344 0.071 VPS13A
vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr18_+_55888750 0.071 NM_001144966
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr5_+_86676620 0.071


chr6_-_149806116 0.071 NM_207360
ZC3H12D
zinc finger CCCH-type containing 12D
chr15_+_39542884 0.070 NM_207445
C15orf54
chromosome 15 open reading frame 54
chr2_+_234580504 0.070 NM_021027
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr20_-_30539803 0.069 PDRG1
p53 and DNA-damage regulated 1
chr4_+_123844210 0.069 NM_145207
SPATA5
spermatogenesis associated 5
chr10_-_35103894 0.069 NM_001184785
NM_001184786
NM_001184787
NM_001184788
NM_001184789
NM_001184790
NM_001184791
NM_001184792
NM_001184793
NM_001184794
NM_019619
PARD3










par-3 partitioning defective 3 homolog (C. elegans)










chr7_+_100331248 0.067 NM_003386
NM_173059
ZAN

zonadhesin

chr3_+_23851933 0.067 NM_001202476
UBE2E1
ubiquitin-conjugating enzyme E2E 1
chr13_+_113633625 0.067 MCF2L
MCF.2 cell line derived transforming sequence-like
chr16_+_81812899 0.067 PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr5_+_140213968 0.066 NM_018910
NM_031852
PCDHA7

protocadherin alpha 7

chr5_+_147582338 0.066 NM_001195290
NM_205841
SPINK6

serine peptidase inhibitor, Kazal type 6

chr9_-_104147261 0.065 NM_001701
BAAT
bile acid CoA: amino acid N-acyltransferase (glycine N-choloyltransferase)
chr3_-_167191808 0.064 NM_006217
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr2_+_234601511 0.064 NM_001072
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr3_-_99833348 0.064 NM_001042459
NM_182909
FILIP1L

filamin A interacting protein 1-like

chr12_-_112630525 0.064 C12orf51
chromosome 12 open reading frame 51
chr14_-_81408030 0.064 CEP128
centrosomal protein 128kDa

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.