Motif ID: PRRX1,2.p2

Z-value: 1.756


Transcription factors associated with PRRX1,2.p2:

Gene SymbolEntrez IDGene Name
PRRX1 5396 paired related homeobox 1
PRRX2 51450 paired related homeobox 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PRRX1hg19_v1_chr1_+_170633312_170633413-0.491.9e-01Click!
PRRX2hg19_v1_chr9_+_132428016_132428116-0.402.9e-01Click!


Activity profile for motif PRRX1,2.p2.

activity profile for motif PRRX1,2.p2


Sorted Z-values histogram for motif PRRX1,2.p2

Sorted Z-values for motif PRRX1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PRRX1,2.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_99279935 2.499 NM_001160154
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr6_+_167525294 2.226 NM_004367
CCR6
chemokine (C-C motif) receptor 6
chr7_+_94297448 2.144 PEG10
paternally expressed 10
chr2_-_77749335 2.008 NM_001134745
NM_024993
LRRTM4

leucine rich repeat transmembrane neuronal 4

chr7_-_96633608 1.834 DLX6-AS1
DLX6 antisense RNA 1 (non-protein coding)
chr10_-_113933517 1.764 GPAM
glycerol-3-phosphate acyltransferase, mitochondrial
chr12_+_9142136 1.692 NM_005810
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr5_+_140602914 1.645 NM_018934
PCDHB14
protocadherin beta 14
chr9_-_14086901 1.611 NFIB
nuclear factor I/B
chr15_+_34261088 1.571 NM_012125
CHRM5
cholinergic receptor, muscarinic 5
chr6_-_32908583 1.569 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr11_+_6942204 1.559 NM_001004684
OR2D3
olfactory receptor, family 2, subfamily D, member 3
chr12_-_16760935 1.477 NM_001001395
NM_001243609
LMO3

LIM domain only 3 (rhombotin-like 2)

chr7_-_107443631 1.428 NM_000111
SLC26A3
solute carrier family 26, member 3
chr16_+_72088507 1.423 NM_001126102
NM_005143
HP

haptoglobin

chr3_+_180320955 1.422 TTC14
tetratricopeptide repeat domain 14
chrX_-_24690740 1.400 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr5_+_140782367 1.333 NM_018921
NM_032089
PCDHGA9

protocadherin gamma subfamily A, 9

chr4_-_46125929 1.319 NM_173536
GABRG1
gamma-aminobutyric acid (GABA) A receptor, gamma 1
chr17_-_10372875 1.256 NM_017533
MYH4
myosin, heavy chain 4, skeletal muscle
chr1_+_186265404 1.237 NM_001127708
NM_001127709
NM_001127710
NM_005807
PRG4



proteoglycan 4



chrX_+_99839789 1.211 NM_022144
TNMD
tenomodulin
chr18_-_21891469 1.186 NM_001242508
OSBPL1A
oxysterol binding protein-like 1A
chr12_-_16759939 1.183 NM_001243613
LMO3
LIM domain only 3 (rhombotin-like 2)
chr5_+_69321071 1.155 NM_001178087
NM_022978
NM_021967
NM_022968
SERF1B

SERF1A

small EDRK-rich factor 1B (centromeric)

small EDRK-rich factor 1A (telomeric)

chr3_+_170139027 1.151 NM_001185056
CLDN11
claudin 11
chr1_+_244216506 1.143 NM_006352
ZNF238
zinc finger protein 238
chr7_-_27205123 1.140 HOXA9
homeobox A9
chr7_+_95115212 1.138 NM_016116
NM_145872
ASB4

ankyrin repeat and SOCS box containing 4

chrX_-_129519420 1.128 NM_178471
GPR119
G protein-coupled receptor 119
chr8_-_95449131 1.115 NM_001205263
RAD54B
RAD54 homolog B (S. cerevisiae)
chr5_-_111312522 1.109 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr5_-_36301999 1.104 NM_001161429
NM_145000
RANBP3L

RAN binding protein 3-like

chr7_-_115670774 1.097 TFEC
transcription factor EC
chr4_-_164534656 1.088 NM_017923
MARCH1
membrane-associated ring finger (C3HC4) 1
chr4_-_70505359 1.080 NM_001105677
UGT2A2
UDP glucuronosyltransferase 2 family, polypeptide A2
chr6_+_136172802 1.080 NM_018945
PDE7B
phosphodiesterase 7B
chr2_-_55199894 1.077


chr1_+_151032866 1.066 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr4_-_2230957 1.065 NM_181808
POLN
polymerase (DNA directed) nu
chr6_+_26365397 1.061 NM_001197247
NM_001197249
NM_007047
NM_001197248
BTN3A2



butyrophilin, subfamily 3, member A2



chr2_+_132480063 1.059 NM_013310
C2orf27A
chromosome 2 open reading frame 27A
chr1_-_39347258 1.056 NM_030772
GJA9-MYCBP
GJA9
GJA9-MYCBP readthrough
gap junction protein, alpha 9, 59kDa
chr5_+_67586466 1.043 NM_181504
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr17_-_26220372 1.043 NM_001076680
C17orf108
chromosome 17 open reading frame 108
chr8_+_107738239 1.037 NM_001198534
NM_001198535
OXR1

oxidation resistance 1

chr17_+_67498391 1.034 MAP2K6
mitogen-activated protein kinase kinase 6
chr6_+_83072922 1.030 NM_006670
TPBG
trophoblast glycoprotein
chr1_+_92632608 1.027 NM_015237
KIAA1107
KIAA1107
chr10_-_70066594 1.016 PBLD
phenazine biosynthesis-like protein domain containing
chr5_+_140557370 1.011 NM_019120
PCDHB8
protocadherin beta 8
chr1_+_151032880 1.006 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr2_-_188312872 1.005 NM_005795
CALCRL
calcitonin receptor-like
chr7_-_84751246 1.001 NM_152754
SEMA3D
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr6_-_75965845 0.995 TMEM30A
transmembrane protein 30A
chr10_-_129691202 0.985 NM_152311
CLRN3
clarin 3
chr1_+_151032683 0.982 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr16_-_51185150 0.978 NM_002968
SALL1
sal-like 1 (Drosophila)
chr6_+_131894343 0.976 NM_000045
NM_001244438
ARG1

arginase, liver

chr1_-_162346579 0.969 NM_182581
C1orf111
chromosome 1 open reading frame 111
chr2_+_177016112 0.965 NM_014621
HOXD4
homeobox D4
chr12_+_89744714 0.951 LOC100131490
uncharacterized LOC100131490
chr5_+_140792507 0.951 NM_018913
NM_032090
PCDHGA10

protocadherin gamma subfamily A, 10

chr8_-_102803196 0.946 NCALD
neurocalcin delta
chr1_+_151032906 0.939 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr5_+_126859157 0.936 PRRC1
proline-rich coiled-coil 1
chr10_-_129691047 0.933


chr12_-_122240827 0.927


chr1_+_84768333 0.927 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr7_-_27205148 0.924 NM_152739
HOXA9
homeobox A9
chr6_+_132873829 0.922 NM_053278
TAAR8
trace amine associated receptor 8
chr10_+_111765725 0.914 NM_019903
ADD3
adducin 3 (gamma)
chr6_-_76782204 0.912 NM_001563
IMPG1
interphotoreceptor matrix proteoglycan 1
chr12_-_10282680 0.900 NM_022570
NM_197947
NM_197948
NM_197949
NM_197950
NM_197954
CLEC7A





C-type lectin domain family 7, member A





chr10_+_115312777 0.892 NM_004132
HABP2
hyaluronan binding protein 2
chr9_-_95298251 0.891 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr5_+_140529619 0.888 NM_018939
PCDHB6
protocadherin beta 6
chr9_-_77643307 0.887 NM_152420
C9orf41
chromosome 9 open reading frame 41
chr20_+_5987897 0.883 NM_001127458
CRLS1
cardiolipin synthase 1
chr12_+_93096618 0.868 NM_001037671
NM_001178097
C12orf74

chromosome 12 open reading frame 74

chr8_-_102803438 0.865 NM_032041
NCALD
neurocalcin delta
chr7_+_2557496 0.849 NM_002304
LFNG
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr13_-_95131718 0.847 NM_001129889
NM_001922
DCT

dopachrome tautomerase (dopachrome delta-isomerase, tyrosine-related protein 2)

chr11_+_118398147 0.841 NM_001080441
TTC36
tetratricopeptide repeat domain 36
chr1_-_32385258 0.837 NM_001195100
NM_001195101
PTP4A2

protein tyrosine phosphatase type IVA, member 2

chr12_+_54422193 0.836 NM_004503
HOXC6
homeobox C6
chr7_-_99474655 0.836 NM_001005276
OR2AE1
olfactory receptor, family 2, subfamily AE, member 1
chr6_+_26251826 0.835 NM_003524
HIST1H2BH
histone cluster 1, H2bh
chr14_-_92413738 0.831 FBLN5
fibulin 5
chr12_+_54410893 0.826 HOXC5
HOXC6
homeobox C5
homeobox C6
chr1_-_190446701 0.816 NM_199051
FAM5C
family with sequence similarity 5, member C
chr6_-_130031278 0.814 NM_033515
ARHGAP18
Rho GTPase activating protein 18
chr3_-_123339178 0.808 MYLK
myosin light chain kinase
chr10_+_102123420 0.806


chr1_-_216896640 0.805 NM_001243515
NM_001243518
NM_001243519
NM_001438
ESRRG



estrogen-related receptor gamma



chr1_+_104097321 0.799 NM_020978
AMY2B
amylase, alpha 2B (pancreatic)
chr8_+_17396285 0.797 NM_001164771
NM_003046
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr3_-_186262114 0.793 NM_017541
CRYGS
crystallin, gamma S
chr8_-_17555158 0.792 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr10_+_5406975 0.783 NM_053049
UCN3
urocortin 3 (stresscopin)
chr2_+_216946588 0.781 NM_001142310
NM_001142311
NM_001142312
NM_138390
TMEM169



transmembrane protein 169



chr12_-_9913415 0.779 NM_001781
CD69
CD69 molecule
chr1_-_232651227 0.779 NM_020808
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr2_+_158114109 0.776 NM_014568
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr9_+_70856838 0.775 NM_201453
CBWD5
CBWD3
CBWD6
COBW domain containing 5
COBW domain containing 3
COBW domain containing 6
chr8_+_37595366 0.773


chr2_-_183387063 0.772 NM_005019
NM_001003683
PDE1A

phosphodiesterase 1A, calmodulin-dependent

chr1_+_84630575 0.771 NM_001242860
NM_001242861
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr3_-_167191808 0.770 NM_006217
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr12_-_89745753 0.769 DUSP6
dual specificity phosphatase 6
chr3_-_195310770 0.764 APOD
apolipoprotein D
chr1_+_196946666 0.749 NM_030787
CFHR5
complement factor H-related 5
chr3_-_64672285 0.748 ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr2_+_183943511 0.747 DUSP19
dual specificity phosphatase 19
chr5_+_140480056 0.746 NM_018937
PCDHB3
protocadherin beta 3
chr3_+_122044010 0.746 NM_005213
CSTA
cystatin A (stefin A)
chr9_+_79115548 0.735 NM_001097636
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr12_-_87232635 0.730 NM_013244
MGAT4C
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr12_-_24102563 0.721 NM_006940
SOX5
SRY (sex determining region Y)-box 5
chr3_-_185270258 0.717 NM_139248
LIPH
lipase, member H
chr1_+_171283372 0.715 NM_002022
FMO4
flavin containing monooxygenase 4
chr1_+_15990300 0.713


chr4_-_84035908 0.713 NM_001130715
NM_016619
PLAC8

placenta-specific 8

chr12_-_89745997 0.704 DUSP6
dual specificity phosphatase 6
chr12_+_29376596 0.704 NM_018099
FAR2
fatty acyl CoA reductase 2
chr4_-_38858407 0.697 NM_006068
TLR6
toll-like receptor 6
chr5_-_126409171 0.697 NM_001164478
NM_001164479
C5orf63

chromosome 5 open reading frame 63

chr10_+_95517565 0.694 NM_005097
LGI1
leucine-rich, glioma inactivated 1
chr16_+_72097124 0.694 NM_020995
HPR
haptoglobin-related protein
chr3_+_46448678 0.681 NM_003965
NM_001130910
CCRL2

chemokine (C-C motif) receptor-like 2

chr5_+_81601165 0.681 NM_001017971
ATP6AP1L
ATPase, H+ transporting, lysosomal accessory protein 1-like
chr2_-_180427314 0.679 NM_001113398
ZNF385B
zinc finger protein 385B
chr2_-_158300517 0.676 NM_004288
CYTIP
cytohesin 1 interacting protein
chr11_-_115088628 0.674 CADM1
cell adhesion molecule 1
chr12_-_89746244 0.670 NM_001946
NM_022652
DUSP6

dual specificity phosphatase 6

chr8_-_120651019 0.670 NM_001040092
NM_001130863
NM_006209
ENPP2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr7_+_141478241 0.667 NM_016944
TAS2R4
taste receptor, type 2, member 4
chr6_+_105404922 0.662 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr4_+_88754120 0.660 NM_001184695
NM_001184696
NM_001184697
NM_020203
MEPE



matrix extracellular phosphoglycoprotein



chr1_+_43253660 0.658 NM_001242750
LOC100129924
uncharacterized LOC100129924
chr20_-_34243118 0.658 RBM12
RNA binding motif protein 12
chrX_+_38211735 0.658 NM_000531
OTC
ornithine carbamoyltransferase
chr14_+_78870092 0.657 NM_004796
NRXN3
neurexin 3
chr2_+_183943286 0.653 NM_001142314
NM_080876
DUSP19

dual specificity phosphatase 19

chrM_-_379 0.653


chr1_+_151611331 0.652 SNX27
sorting nexin family member 27
chr4_-_70626429 0.650 NM_014465
SULT1B1
sulfotransferase family, cytosolic, 1B, member 1
chr9_-_86584079 0.646 HNRNPK
heterogeneous nuclear ribonucleoprotein K
chr4_+_113970784 0.646 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr4_-_111563278 0.645 NM_001204397
NM_001204398
NM_001204399
NM_153426
NM_153427
PITX2




paired-like homeodomain 2




chr3_+_171561138 0.645 NM_001164436
TMEM212
transmembrane protein 212
chr1_-_93342706 0.639 NM_001252271
FAM69A
family with sequence similarity 69, member A
chr1_-_173174611 0.636 TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr6_+_155585146 0.629 NM_001001346
CLDN20
claudin 20
chr4_-_84035888 0.628 PLAC8
placenta-specific 8
chr5_-_159827042 0.628 NM_022090
C5orf54
chromosome 5 open reading frame 54
chrX_+_36254050 0.627 NM_001098843
CXorf30
chromosome X open reading frame 30
chr12_+_74931550 0.625 NM_001136262
ATXN7L3B
ataxin 7-like 3B
chr15_-_73051650 0.619


chr17_-_38859976 0.617 NM_019016
KRT24
keratin 24
chr2_-_180610768 0.614 NM_001113397
ZNF385B
zinc finger protein 385B
chr7_-_27142301 0.613 NM_006735
HOXA2
homeobox A2
chr5_+_76435073 0.612


chr2_-_231989755 0.612 NM_000867
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B
chr13_-_86373328 0.610 NM_032229
SLITRK6
SLIT and NTRK-like family, member 6
chr6_-_87804773 0.607 NM_000735
NM_001252383
CGA

glycoprotein hormones, alpha polypeptide

chr12_-_89746238 0.605 DUSP6
dual specificity phosphatase 6
chr5_+_71502700 0.602 MAP1B
microtubule-associated protein 1B
chr21_-_36421630 0.598 RUNX1
runt-related transcription factor 1
chr6_-_33160199 0.597 NM_001163771
NM_080679
NM_080680
NM_080681
COL11A2



collagen, type XI, alpha 2



chr7_-_115670828 0.597 NM_001018058
NM_012252
TFEC

transcription factor EC

chrX_-_107682600 0.594 NM_001847
COL4A6
collagen, type IV, alpha 6
chr18_+_72922725 0.593 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr1_+_81771844 0.591 LPHN2
latrophilin 2
chr11_-_118084073 0.590 NM_153206
AMICA1
adhesion molecule, interacts with CXADR antigen 1
chr6_-_64029847 0.590 NM_001143940
NM_016571
LGSN

lengsin, lens protein with glutamine synthetase domain

chr7_-_14025826 0.590 NM_001163150
NM_001163151
NM_001163152
ETV1


ets variant 1


chr7_-_92855780 0.587 NM_001039372
HEPACAM2
HEPACAM family member 2
chr8_-_17579729 0.584 NM_001001931
MTUS1
microtubule associated tumor suppressor 1
chr3_-_57234279 0.581 NM_003865
HESX1
HESX homeobox 1
chr1_+_50574601 0.577 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr7_-_122339186 0.576 NM_139175
RNF133
ring finger protein 133
chr7_-_99774821 0.576 NM_152742
GPC2
glypican 2
chr10_-_52008312 0.574 NM_001143974
NM_019893
ASAH2

N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2

chr7_-_26232148 0.573 HNRNPA2B1
heterogeneous nuclear ribonucleoprotein A2/B1
chrX_-_13835313 0.573 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr17_-_38821286 0.573 NM_152349
KRT222
keratin 222
chr17_-_1248346 0.572 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr1_-_42965948 0.570 TMSB4XP1
thymosin beta 4, X-linked pseudogene 1
chr5_-_35118223 0.569 NM_001204314
NM_001204315
NM_001204316
NM_001204317
NM_001204318
PRLR




prolactin receptor




chr2_-_21228189 0.569 APOB
apolipoprotein B (including Ag(x) antigen)
chr6_-_75970566 0.568 TMEM30A
transmembrane protein 30A
chr6_+_50786438 0.566 NM_003221
TFAP2B
transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
chr11_+_56756346 0.564 NM_001005323
OR5AK2
olfactory receptor, family 5, subfamily AK, member 2
chr2_+_166428845 0.563 NM_024969
CSRNP3
cysteine-serine-rich nuclear protein 3
chr10_+_74870209 0.563 NM_015901
NUDT13
nudix (nucleoside diphosphate linked moiety X)-type motif 13
chr12_+_64803741 0.563 XPOT
exportin, tRNA (nuclear export receptor for tRNAs)
chr1_-_168106727 0.560 GPR161
G protein-coupled receptor 161
chr11_+_87032428 0.559 TMEM135
transmembrane protein 135
chr6_-_116447225 0.557 NM_000493
COL10A1
collagen, type X, alpha 1

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.