Motif ID: REST.p3

Z-value: 0.792


Transcription factors associated with REST.p3:

Gene SymbolEntrez IDGene Name
REST 5978 RE1-silencing transcription factor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
RESThg19_v1_chr4_+_57775127_57775136-0.314.1e-01Click!


Activity profile for motif REST.p3.

activity profile for motif REST.p3


Sorted Z-values histogram for motif REST.p3

Sorted Z-values for motif REST.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of REST.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_3971032 1.161 DAPK3
death-associated protein kinase 3
chr7_-_100808832 1.094 NM_003378
VGF
VGF nerve growth factor inducible
chr19_-_3971089 1.029 DAPK3
death-associated protein kinase 3
chr3_-_48700317 1.013 NM_001407
CELSR3
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr10_-_102790877 0.804 NM_001195263
NM_024895
PDZD7

PDZ domain containing 7

chr19_-_40724272 0.710 NM_152479
TTC9B
tetratricopeptide repeat domain 9B
chr11_+_45907198 0.644 MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr8_-_145559831 0.638 NM_031309
SCRT1
scratch homolog 1, zinc finger protein (Drosophila)
chr11_+_45907046 0.618 NM_005456
MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr8_-_145752405 0.572 NM_001024678
LRRC24
leucine rich repeat containing 24
chr5_+_33936490 0.571 NM_016568
RXFP3
relaxin/insulin-like family peptide receptor 3
chr20_+_62328002 0.554 NM_003823
TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr5_-_151304322 0.541 NM_000171
NM_001146040
GLRA1

glycine receptor, alpha 1

chr10_+_73555527 0.534 NM_001171933
NM_001171934
CDH23

cadherin-related 23

chr1_+_154540300 0.504 CHRNB2
cholinergic receptor, nicotinic, beta 2 (neuronal)
chr5_-_176037091 0.468 NM_052899
GPRIN1
G protein regulated inducer of neurite outgrowth 1
chr9_-_131038196 0.465 NM_004486
GOLGA2
golgin A2
chr19_-_45927142 0.461 ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr17_+_30813928 0.397 NM_003885
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr19_-_45927081 0.384 ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr19_-_45926819 0.383 NM_202001
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr16_+_67686813 0.375 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr20_+_62328068 0.371 TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr19_-_45926759 0.357 ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr17_+_42385780 0.347 NM_001144825
NM_001144826
NM_006695
RUNDC3A


RUN domain containing 3A


chr17_+_72667255 0.337 NM_175738
RAB37
RAB37, member RAS oncogene family
chr19_-_11639679 0.334 NM_001243204
ECSIT
ECSIT homolog (Drosophila)
chr20_+_33814538 0.334 NM_006690
MMP24
matrix metallopeptidase 24 (membrane-inserted)
chr9_+_131038500 0.323 SWI5
SWI5 recombination repair homolog (yeast)
chr17_-_27332888 0.319 NM_001098635
NM_178860
SEZ6

seizure related 6 homolog (mouse)

chr9_+_131038421 0.318 NM_001040011
SWI5
SWI5 recombination repair homolog (yeast)
chr11_-_75141015 0.306 KLHL35
kelch-like 35 (Drosophila)
chr7_+_8474016 0.295 NXPH1
neurexophilin 1
chr17_+_72667316 0.291 RAB37
RAB37, member RAS oncogene family
chr12_-_29937691 0.283 NM_175861
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr19_-_11639929 0.252 NM_001142464
NM_001142465
NM_016581
ECSIT


ECSIT homolog (Drosophila)


chrX_-_153141398 0.252 NM_000425
NM_001143963
NM_024003
L1CAM


L1 cell adhesion molecule


chr12_+_175872 0.239 NM_001170738
IQSEC3
IQ motif and Sec7 domain 3
chr7_+_8473237 0.232 NXPH1
neurexophilin 1
chr10_-_50970321 0.223 NM_001143996
NM_001143997
NM_018245
OGDHL


oxoglutarate dehydrogenase-like


chr16_+_5008317 0.212 NM_014692
SEC14L5
SEC14-like 5 (S. cerevisiae)
chr4_-_175750377 0.208 NM_001042543
NM_006529
GLRA3

glycine receptor, alpha 3

chr10_+_60937226 0.203 NM_001143774
PHYHIPL
phytanoyl-CoA 2-hydroxylase interacting protein-like
chr7_+_8473584 0.199 NM_152745
NXPH1
neurexophilin 1
chr10_+_28821724 0.195


chrX_-_153141284 0.191 L1CAM
L1 cell adhesion molecule
chr3_+_193853930 0.182 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr15_-_60884615 0.173 NM_134262
RORA
RAR-related orphan receptor A
chr1_-_151689246 0.171 NM_007185
CELF3
CUGBP, Elav-like family member 3
chr11_-_123524881 0.163 SCN3B
sodium channel, voltage-gated, type III, beta
chr10_+_28822387 0.159 NM_016628
NM_100486
WAC

WW domain containing adaptor with coiled-coil

chr14_-_51562044 0.155 TRIM9
tripartite motif containing 9
chr12_-_99288502 0.153 NM_001204065
NM_001204079
NM_001204080
NM_001204081
ANKS1B



ankyrin repeat and sterile alpha motif domain containing 1B



chr20_+_44657858 0.151 SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr20_+_44657812 0.145 NM_020708
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr4_+_158141735 0.143 NM_000826
NM_001083619
NM_001083620
GRIA2


glutamate receptor, ionotropic, AMPA 2


chrX_+_153237990 0.142 NM_003492
TMEM187
transmembrane protein 187
chr12_-_29936685 0.141 NM_001193451
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr17_-_79881304 0.139 NM_032711
MAFG
v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr11_+_22359666 0.134 NM_020346
SLC17A6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr3_+_193853937 0.132 HES1
hairy and enhancer of split 1, (Drosophila)
chr10_+_28822428 0.126 WAC
WW domain containing adaptor with coiled-coil
chr10_+_28822508 0.123 WAC
WW domain containing adaptor with coiled-coil
chr11_-_6676851 0.115 NM_003737
DCHS1
dachsous 1 (Drosophila)
chr10_+_28822062 0.107


chr6_+_43603554 0.102 NM_014628
MAD2L1BP
MAD2L1 binding protein
chr20_-_60795270 0.098 NM_007232
HRH3
histamine receptor H3
chr18_+_57567191 0.094 NM_021127
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr14_-_51561657 0.087 TRIM9
tripartite motif containing 9
chr6_+_43603588 0.066 MAD2L1BP
MAD2L1 binding protein
chr11_-_27721179 0.064 NM_170734
BDNF
brain-derived neurotrophic factor
chr9_-_74061819 0.056 TRPM3
transient receptor potential cation channel, subfamily M, member 3
chr18_-_5197240 0.053 NM_001145194
C18orf42
chromosome 18 open reading frame 42
chrX_-_47479229 0.051 NM_006950
NM_133499
SYN1

synapsin I

chr19_-_45737466 0.048 NM_138568
EXOC3L2
exocyst complex component 3-like 2
chr14_+_93389444 0.047 NM_001275
CHGA
chromogranin A (parathyroid secretory protein 1)
chr2_-_42720476 0.046 KCNG3
potassium voltage-gated channel, subfamily G, member 3
chr1_+_171750829 0.045 METTL13
methyltransferase like 13
chr1_-_209825797 0.044 NM_000228
LAMB3
laminin, beta 3
chr7_+_145813452 0.038 NM_014141
CNTNAP2
contactin associated protein-like 2
chr14_-_58332591 0.036 NM_001206920
SLC35F4
solute carrier family 35, member F4
chrX_-_49056638 0.032 NM_003179
SYP
synaptophysin
chr1_+_101004456 0.030 GPR88
G protein-coupled receptor 88
chr2_-_220083394 0.028 ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr1_+_171750807 0.023 METTL13
methyltransferase like 13
chr20_-_13765509 0.021 NM_016649
ESF1
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr16_+_69345250 0.020 NM_013245
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr17_-_7218370 0.020 NM_004489
GPS2
G protein pathway suppressor 2
chr1_+_171750760 0.020 NM_001007239
NM_014955
NM_015935
METTL13


methyltransferase like 13


chr6_+_43149925 0.020 CUL9
cullin 9
chr2_-_96810775 0.018 DUSP2
dual specificity phosphatase 2
chr11_-_1769086 0.015 IFITM10
interferon induced transmembrane protein 10
chr1_-_241683060 0.014 NM_000143
FH
fumarate hydratase
chr5_+_141303366 0.014 NM_001142603
NM_014773
KIAA0141

KIAA0141

chr1_-_241683011 0.013 FH
fumarate hydratase
chr6_-_71666740 0.013 NM_080742
B3GAT2
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr6_+_43149905 0.009 NM_015089
CUL9
cullin 9
chr17_-_3599487 0.009 NM_001204519
NM_001204520
NM_002561
NM_175080
P2RX5-TAX1BP3
P2RX5



P2RX5-TAX1BP3 readthrough
purinergic receptor P2X, ligand-gated ion channel, 5



chr1_-_13184325 0.009 NM_001136561
LOC440563
heterogeneous nuclear ribonucleoprotein C-like
chr10_+_89419352 0.008 NM_001015880
NM_004670
PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

chr3_+_52812438 0.008 NM_001166434
ITIH1
inter-alpha-trypsin inhibitor heavy chain 1
chr5_+_141303463 0.007 KIAA0141
KIAA0141
chr10_-_102790850 0.005 PDZD7
PDZ domain containing 7
chr22_+_31795538 0.002 NM_004147
DRG1
developmentally regulated GTP binding protein 1
chr15_-_72612127 0.002 CELF6
CUGBP, Elav-like family member 6
chr5_-_69881965 0.000 SMA4
glucuronidase, beta pseudogene

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.