Motif ID: CCUUCAU

Z-value: 0.816


Mature miRNA associated with seed CCUUCAU:

NamemiRBase Accession
hsa-miR-205 MIMAT0000266



Activity profile for motif CCUUCAU.

activity profile for motif CCUUCAU


Sorted Z-values histogram for motif CCUUCAU

Sorted Z-values for motif CCUUCAU



Network of associatons between targets according to the STRING database.



First level regulatory network of CCUUCAU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_-_60919642 1.206 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chr15_-_60884615 1.138 NM_134262
RORA
RAR-related orphan receptor A
chr15_-_61521478 1.115 NM_134261
RORA
RAR-related orphan receptor A
chr9_-_4300028 1.062 NM_001042413
GLIS3
GLIS family zinc finger 3
chr9_-_4152182 1.043 NM_152629
GLIS3
GLIS family zinc finger 3
chr1_+_110009099 0.900 NM_001040709
SYPL2
synaptophysin-like 2
chr1_-_33841142 0.793 NM_198040
PHC2
polyhomeotic homolog 2 (Drosophila)
chr8_+_16884745 0.724 NM_181723
EFHA2
EF-hand domain family, member A2
chr1_-_33815498 0.719 NM_004427
PHC2
polyhomeotic homolog 2 (Drosophila)
chr16_+_50582193 0.717 NM_033119
NKD1
naked cuticle homolog 1 (Drosophila)
chr11_-_83984230 0.715 NM_001142700
DLG2
discs, large homolog 2 (Drosophila)
chr2_-_145277879 0.694 NM_001171653
NM_014795
ZEB2

zinc finger E-box binding homeobox 2

chr2_-_69870976 0.691 NM_014911
AAK1
AP2 associated kinase 1
chr1_-_224033673 0.657 NM_001031685
NM_005426
TP53BP2

tumor protein p53 binding protein, 2

chr11_-_83393436 0.644 NM_001142702
DLG2
discs, large homolog 2 (Drosophila)
chr11_+_71935824 0.643 NM_001567
INPPL1
inositol polyphosphate phosphatase-like 1
chr11_-_84634437 0.613 NM_001364
DLG2
discs, large homolog 2 (Drosophila)
chr14_+_55034329 0.598 NM_001161576
NM_015589
SAMD4A

sterile alpha motif domain containing 4A

chr5_+_167718485 0.584 NM_001161661
NM_001161662
NM_015238
WWC1


WW and C2 domain containing 1


chr16_+_69599868 0.577 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chr2_-_161350304 0.561 NM_002897
NM_016836
RBMS1

RNA binding motif, single stranded interacting protein 1

chr14_+_55221505 0.558 NM_001161577
SAMD4A
sterile alpha motif domain containing 4A
chr20_-_3388219 0.517 NM_001009984
C20orf194
chromosome 20 open reading frame 194
chr10_+_8096633 0.458 NM_001002295
NM_002051
GATA3

GATA binding protein 3

chr4_+_75230856 0.442 NM_001432
EREG
epiregulin
chr11_-_85338313 0.441 NM_001142699
DLG2
discs, large homolog 2 (Drosophila)
chr10_+_97803064 0.435 NM_001134375
NM_001134376
NM_019084
CCNJ


cyclin J


chrX_-_103087106 0.432 NM_016370
RAB9B
RAB9B, member RAS oncogene family
chr9_-_138987096 0.409 NM_144653
NACC2
NACC family member 2, BEN and BTB (POZ) domain containing
chr15_-_40401041 0.370 NM_001003940
BMF
Bcl2 modifying factor
chr19_+_13906207 0.368 NM_023072
ZSWIM4
zinc finger, SWIM-type containing 4
chr15_+_85359910 0.361 NM_020778
ALPK3
alpha-kinase 3
chr11_+_61447816 0.358 NM_006133
DAGLA
diacylglycerol lipase, alpha
chr6_+_108881010 0.350 NM_201559
FOXO3
forkhead box O3
chr3_-_169899519 0.345 NM_024947
PHC3
polyhomeotic homolog 3 (Drosophila)
chr6_+_45389818 0.340 NM_004348
RUNX2
runt-related transcription factor 2
chr5_-_37839781 0.335 NM_000514
GDNF
glial cell derived neurotrophic factor
chr6_-_111136407 0.333 NM_015076
CDK19
cyclin-dependent kinase 19
chr19_-_56092184 0.318 NM_152600
ZNF579
zinc finger protein 579
chr17_-_37607314 0.317 NM_004774
MED1
mediator complex subunit 1
chr6_-_31830593 0.314 NM_000434
NEU1
sialidase 1 (lysosomal sialidase)
chr7_+_155437182 0.309 NM_053043
RBM33
RNA binding motif protein 33
chr3_+_187943192 0.308 NM_001167671
LPP
LIM domain containing preferred translocation partner in lipoma
chr16_+_50186809 0.305 NM_001040284
NM_001040285
PAPD5

PAP associated domain containing 5

chr17_+_76000248 0.283 NM_001142640
NM_018996
TNRC6C

trinucleotide repeat containing 6C

chr7_-_79082870 0.276 NM_012301
MAGI2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr1_-_201438150 0.276 NM_012396
PHLDA3
pleckstrin homology-like domain, family A, member 3
chr15_-_74726258 0.269 NM_001146029
NM_003612
SEMA7A

semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)

chr9_-_22009270 0.265 NM_004936
NM_078487
CDKN2B

cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)

chr5_-_37835928 0.265 NM_001190468
NM_001190469
GDNF

glial cell derived neurotrophic factor

chr6_+_108882068 0.265 NM_001455
FOXO3
forkhead box O3
chr15_-_40398286 0.264 NM_001003942
NM_001003943
BMF

Bcl2 modifying factor

chr13_+_44453968 0.262 NM_153218
LACC1
laccase (multicopper oxidoreductase) domain containing 1
chr19_-_7293876 0.262 NM_000208
NM_001079817
INSR

insulin receptor

chr1_-_8086392 0.258 NM_018948
ERRFI1
ERBB receptor feedback inhibitor 1
chr11_-_84028379 0.251 NM_001206769
DLG2
discs, large homolog 2 (Drosophila)
chr1_-_41628688 0.251 NM_001172221
SCMH1
sex comb on midleg homolog 1 (Drosophila)
chr17_-_63557615 0.245 NM_004655
AXIN2
axin 2
chr19_+_11200037 0.240 NM_000527
NM_001195798
NM_001195799
NM_001195800
NM_001195802
NM_001195803
LDLR





low density lipoprotein receptor





chrX_+_147582133 0.238 NM_001169122
NM_001169123
NM_001169124
NM_001169125
NM_002025
AFF2




AF4/FMR2 family, member 2




chr1_-_214724974 0.238 NM_005401
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr17_+_40118696 0.238 NM_033133
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr15_-_40398573 0.236 NM_033503
BMF
Bcl2 modifying factor
chrX_-_134049248 0.235 NM_019556
MOSPD1
motile sperm domain containing 1
chr10_-_73533196 0.230 NM_022153
C10orf54
chromosome 10 open reading frame 54
chr2_-_206950895 0.225 NM_017759
INO80D
INO80 complex subunit D
chrX_+_70521627 0.224 NM_012278
ITGB1BP2
integrin beta 1 binding protein (melusin) 2
chr8_+_75736771 0.224 NM_015886
PI15
peptidase inhibitor 15
chr13_+_44453419 0.224 NM_001128303
LACC1
laccase (multicopper oxidoreductase) domain containing 1
chr15_+_90544608 0.222 NM_198526
ZNF710
zinc finger protein 710
chr3_-_197476567 0.219 NM_001145642
KIAA0226
KIAA0226
chr19_+_13105970 0.217 NM_002501
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr1_+_178310605 0.213 NM_004841
RASAL2
RAS protein activator like 2
chr1_-_120612301 0.213 NM_001200001
NM_024408
NOTCH2

notch 2

chr3_-_197463713 0.209 NM_014687
KIAA0226
KIAA0226
chr14_-_74253876 0.209 NM_001043318
C14orf43
chromosome 14 open reading frame 43
chrX_-_73834460 0.208 NM_016120
NM_183353
RLIM

ring finger protein, LIM domain interacting

chr3_+_88188261 0.206 NM_018293
ZNF654
zinc finger protein 654
chrX_+_147800610 0.204 NM_001170628
AFF2
AF4/FMR2 family, member 2
chr3_+_187930720 0.204 NM_005578
LPP
LIM domain containing preferred translocation partner in lipoma
chr12_+_64238511 0.198 NM_020762
SRGAP1
SLIT-ROBO Rho GTPase activating protein 1
chr3_+_46742822 0.196 NM_147196
TMIE
transmembrane inner ear
chr3_+_141043054 0.195 NM_001080412
ZBTB38
zinc finger and BTB domain containing 38
chr3_-_49823626 0.194 NM_001242829
IP6K1
inositol hexakisphosphate kinase 1
chr14_+_61788398 0.192 NM_006255
PRKCH
protein kinase C, eta
chr2_+_10184371 0.192 NM_001177718
KLF11
Kruppel-like factor 11
chr5_-_37835592 0.190 NM_199231
GDNF
glial cell derived neurotrophic factor
chr11_-_36531767 0.189 NM_004620
NM_145803
TRAF6

TNF receptor-associated factor 6

chr20_+_11871364 0.187 NM_181443
BTBD3
BTB (POZ) domain containing 3
chr5_-_107006585 0.185 NM_001962
EFNA5
ephrin-A5
chr22_-_41842853 0.184 NM_016272
TOB2
transducer of ERBB2, 2
chr6_+_32940860 0.183 NM_001199456
BRD2
bromodomain containing 2
chr4_+_184020343 0.182 NM_024949
WWC2
WW and C2 domain containing 2
chr3_-_87040246 0.181 NM_016206
VGLL3
vestigial like 3 (Drosophila)
chr22_+_40573879 0.179 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr4_+_15004297 0.178 NM_001177381
NM_001177382
NM_001177383
NM_001177384
NM_182485
NM_182646
CPEB2





cytoplasmic polyadenylation element binding protein 2





chr14_-_89020888 0.178 NM_007039
PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr10_+_98592658 0.173 NM_032440
LCOR
ligand dependent nuclear receptor corepressor
chr1_-_149982528 0.173 NM_020205
OTUD7B
OTU domain containing 7B
chr5_-_138775213 0.173 NM_152686
DNAJC18
DnaJ (Hsp40) homolog, subfamily C, member 18
chr3_-_49823972 0.172 NM_001006115
NM_153273
IP6K1

inositol hexakisphosphate kinase 1

chr16_+_30772932 0.170 NM_001207033
NM_001207034
NM_014771
RNF40


ring finger protein 40


chr10_+_31608097 0.170 NM_001174093
NM_001174095
NM_001174096
NM_030751
ZEB1



zinc finger E-box binding homeobox 1



chr4_-_185747183 0.170 NM_001995
ACSL1
acyl-CoA synthetase long-chain family member 1
chr11_-_74109417 0.169 NM_173582
PGM2L1
phosphoglucomutase 2-like 1
chr9_-_123689172 0.168 NM_005658
TRAF1
TNF receptor-associated factor 1
chr1_-_41627045 0.168 NM_001031694
SCMH1
sex comb on midleg homolog 1 (Drosophila)
chr13_-_41556360 0.167 NM_001145353
ELF1
E74-like factor 1 (ets domain transcription factor)
chr2_+_74273449 0.167 NM_144993
TET3
tet methylcytosine dioxygenase 3
chr1_+_167189948 0.165 NM_001198786
NM_002697
POU2F1

POU class 2 homeobox 1

chr13_-_41593491 0.165 NM_172373
ELF1
E74-like factor 1 (ets domain transcription factor)
chr6_+_32938658 0.165 NM_001113182
BRD2
bromodomain containing 2
chr15_+_83776323 0.163 NM_001144903
NM_023003
TM6SF1

transmembrane 6 superfamily member 1

chr3_-_116164363 0.162 NM_002338
LSAMP
limbic system-associated membrane protein
chr7_+_102073953 0.162 NM_001126340
NM_032831
ORAI2

ORAI calcium release-activated calcium modulator 2

chr2_+_70142152 0.161 NM_001202513
NM_001202514
NM_002357
MXD1


MAX dimerization protein 1


chr6_+_32939371 0.159 NM_001199455
BRD2
bromodomain containing 2
chr12_+_110437233 0.159 NM_033121
ANKRD13A
ankyrin repeat domain 13A
chr10_+_114135937 0.158 NM_016234
ACSL5
acyl-CoA synthetase long-chain family member 5
chr6_-_44280986 0.158 NM_020745
AARS2
alanyl-tRNA synthetase 2, mitochondrial (putative)
chr15_+_74900712 0.156 NM_003992
CLK3
CDC-like kinase 3
chr11_-_70935807 0.156 NM_012309
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr3_+_156394452 0.155 NM_001184718
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr3_-_135913276 0.155 NM_001145417
MSL2
male-specific lethal 2 homolog (Drosophila)
chr8_+_75262616 0.155 NM_018972
NM_001040875
GDAP1

ganglioside-induced differentiation-associated protein 1

chr1_-_155904186 0.154 NM_014949
KIAA0907
KIAA0907
chr11_+_73087396 0.154 NM_152222
RELT
RELT tumor necrosis factor receptor
chr17_+_33570079 0.151 NM_144975
SLFN5
schlafen family member 5
chr5_+_149380168 0.150 NM_014983
HMGXB3
HMG box domain containing 3
chr1_+_178062829 0.150 NM_170692
RASAL2
RAS protein activator like 2
chr3_-_187454247 0.149 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr17_-_77478562 0.148 NM_001082575
RBFOX3
RNA binding protein, fox-1 homolog (C. elegans) 3
chr2_+_205410465 0.148 NM_057177
NM_152526
NM_205863
PARD3B


par-3 partitioning defective 3 homolog B (C. elegans)


chr3_-_187452669 0.147 NM_001134738
BCL6
B-cell CLL/lymphoma 6
chr1_-_11866079 0.147 NM_005957
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr10_-_94050799 0.145 NM_014912
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr9_-_123691442 0.145 NM_001190945
TRAF1
TNF receptor-associated factor 1
chr10_+_114133838 0.143 NM_203379
ACSL5
acyl-CoA synthetase long-chain family member 5
chr10_+_31610063 0.142 NM_001128128
NM_001174094
ZEB1

zinc finger E-box binding homeobox 1

chr12_-_116714910 0.141 NM_015335
MED13L
mediator complex subunit 13-like
chr14_+_31028328 0.141 NM_017769
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr12_-_57472573 0.141 NM_001130963
NM_015257
TMEM194A

transmembrane protein 194A

chr2_+_10183630 0.140 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr17_-_8151373 0.140 NM_025099
CTC1
CTS telomere maintenance complex component 1
chr2_-_175869910 0.139 NM_001822
NM_001025201
CHN1

chimerin (chimaerin) 1

chr1_+_95558072 0.138 NM_001199679
TMEM56
transmembrane protein 56
chr6_+_20402040 0.137 NM_001949
E2F3
E2F transcription factor 3
chr22_+_40440664 0.137 NM_001024843
TNRC6B
trinucleotide repeat containing 6B
chr22_-_29075708 0.137 NM_001145418
TTC28
tetratricopeptide repeat domain 28
chr1_+_167298280 0.136 NM_001198783
POU2F1
POU class 2 homeobox 1
chr1_-_196577438 0.136 NM_198503
KCNT2
potassium channel, subfamily T, member 2
chr20_+_49348050 0.135 NM_032521
PARD6B
par-6 partitioning defective 6 homolog beta (C. elegans)
chr3_+_156392204 0.134 NM_015508
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr1_+_151170978 0.134 NM_001135636
NM_001135637
NM_001135638
NM_003557
PIP5K1A



phosphatidylinositol-4-phosphate 5-kinase, type I, alpha



chr3_+_156392714 0.133 NM_001184717
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr15_+_74907334 0.133 NM_001130028
CLK3
CDC-like kinase 3
chr3_+_152880024 0.132 NM_002886
RAP2B
RAP2B, member of RAS oncogene family
chr3_-_24536176 0.132 NM_000461
NM_001128176
NM_001128177
NM_001252634
THRB



thyroid hormone receptor, beta



chr8_+_86099909 0.132 NM_001083589
E2F5
E2F transcription factor 5, p130-binding
chr6_+_147829784 0.131 NM_001030060
SAMD5
sterile alpha motif domain containing 5
chr2_-_97304080 0.131 NM_001115016
NM_017991
KANSL3

KAT8 regulatory NSL complex subunit 3

chr3_+_195447751 0.129 NM_152673
MUC20
mucin 20, cell surface associated
chr12_-_82752154 0.129 NM_014167
CCDC59
coiled-coil domain containing 59
chr15_+_91073094 0.128 NM_001042574
NM_022769
CRTC3

CREB regulated transcription coactivator 3

chr2_+_219575507 0.128 NM_014640
TTLL4
tubulin tyrosine ligase-like family, member 4
chr17_+_38465422 0.128 NM_000964
RARA
retinoic acid receptor, alpha
chr10_+_114135013 0.125 NM_203380
ACSL5
acyl-CoA synthetase long-chain family member 5
chr1_+_241695433 0.125 NM_003679
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr3_-_135914654 0.124 NM_018133
MSL2
male-specific lethal 2 homolog (Drosophila)
chr5_+_56110899 0.124 NM_005921
MAP3K1
mitogen-activated protein kinase kinase kinase 1
chr6_-_88411984 0.124 NM_018064
AKIRIN2
akirin 2
chr2_-_64881040 0.123 NM_014755
SERTAD2
SERTA domain containing 2
chr3_+_187871473 0.123 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr5_+_78531848 0.122 NM_152405
JMY
junction mediating and regulatory protein, p53 cofactor
chr15_-_74726000 0.122 NM_001146030
SEMA7A
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr3_+_126707380 0.122 NM_032242
PLXNA1
plexin A1
chr3_-_187463474 0.122 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr8_-_12990731 0.121 NM_006094
DLC1
deleted in liver cancer 1
chr16_+_28962127 0.120 NM_032815
NFATC2IP
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein
chr20_-_33880203 0.119 NM_178468
FAM83C
family with sequence similarity 83, member C
chr17_+_62075710 0.118 NM_001164257
NM_001191029
NM_001191030
NM_001191031
C17orf72



chromosome 17 open reading frame 72



chr9_-_99329092 0.116 NM_001077181
CDC14B
CDC14 cell division cycle 14 homolog B (S. cerevisiae)
chr2_-_240322620 0.115 NM_006037
HDAC4
histone deacetylase 4
chr1_-_179198814 0.115 NM_001136001
NM_001168236
NM_001168237
NM_001168238
NM_007314
ABL2




v-abl Abelson murine leukemia viral oncogene homolog 2




chr11_-_70507911 0.114 NM_133266
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr1_+_154975041 0.114 NM_001252405
NM_015872
ZBTB7B

zinc finger and BTB domain containing 7B

chr11_+_35965530 0.114 NM_174902
LDLRAD3
low density lipoprotein receptor class A domain containing 3
chr7_-_72722786 0.113 NM_001168347
NM_001168348
NM_018044
NM_148956
NSUN5



NOP2/Sun domain family, member 5



chr18_+_7567313 0.113 NM_001105244
NM_002845
PTPRM

protein tyrosine phosphatase, receptor type, M

chr11_+_73087670 0.112 NM_032871
RELT
RELT tumor necrosis factor receptor
chr1_-_179846894 0.112 NM_001199260
NM_022347
NM_145034
TOR1AIP2


torsin A interacting protein 2


chr3_+_180630054 0.111 NM_001013438
NM_001013439
NM_005087
FXR1


fragile X mental retardation, autosomal homolog 1


chr1_+_95582827 0.111 NM_152487
TMEM56
transmembrane protein 56
chr12_-_29937691 0.109 NM_175861
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr1_+_22778343 0.108 NM_001083621
NM_014870
ZBTB40

zinc finger and BTB domain containing 40

chr4_+_95679075 0.108 NM_001203
BMPR1B
bone morphogenetic protein receptor, type IB
chr18_-_45456925 0.107 NM_005901
SMAD2
SMAD family member 2
chr3_+_195451097 0.106 NM_001098516
MUC20
mucin 20, cell surface associated
chr6_+_43737937 0.105 NM_001025366
NM_001025367
NM_001025368
NM_001025369
NM_001025370
NM_001033756
NM_001171622
NM_001171623
NM_001171624
NM_001171625
NM_001171626
NM_001171627
NM_001171628
NM_001171629
NM_001171630
NM_001204384
NM_001204385
NM_003376
VEGFA

















vascular endothelial growth factor A

















chr4_+_140374960 0.105 NM_031296
RAB33B
RAB33B, member RAS oncogene family

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
20.37 3.48e-02 GO:0045893 positive regulation of transcription, DNA-dependent
19.00 4.00e-02 GO:0051254 positive regulation of RNA metabolic process
18.82 4.08e-02 GO:0010628 positive regulation of gene expression
17.09 4.97e-02 GO:0010557 positive regulation of macromolecule biosynthetic process

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
12.45 3.07e-02 GO:0003700 sequence-specific DNA binding transcription factor activity