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• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: E2F1..5.p2

Z-value: 5.243

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr2_+_16080639	19.852	NM_005378	MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr2_+_16080559	18.343		MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr19_+_4909447	10.879	NM_001048201	UHRF1	ubiquitin-like with PHD and ring finger domains 1
chr6_+_27100784	9.626	NM_021064	HIST1H2AG	histone cluster 1, H2ag
chr1_-_23857711	8.703	NM_004091	E2F2	E2F transcription factor 2
chr1_-_23857284	8.440		E2F2	E2F transcription factor 2
chr20_-_5100443	7.886	NM_182649	PCNA	proliferating cell nuclear antigen
chr15_+_66994669	7.077	NM_005585	SMAD6	SMAD family member 6
chr15_-_64673569	6.771	NM_001029989 NM_014736	KIAA0101	KIAA0101
chr19_+_4910166	6.704		UHRF1	ubiquitin-like with PHD and ring finger domains 1
chr2_-_136633934	6.610		MCM6	minichromosome maintenance complex component 6
chr2_-_136634002	6.473	NM_005915	MCM6	minichromosome maintenance complex component 6
chr12_-_77459198	6.439	NM_203394	E2F7	E2F transcription factor 7
chr2_+_232573226	5.914	NM_001099285 NM_002823	PTMA	prothymosin, alpha
chr7_+_129074235	5.503	NM_001134336 NM_020704	FAM40B	family with sequence similarity 40, member B
chr15_+_66995414	5.458		SMAD6	SMAD family member 6
chr6_+_135502521	5.125		MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr6_+_135502445	5.095	NM_001130172 NM_001130173 NM_001161656 NM_001161657 NM_001161658 NM_001161659 NM_001161660 NM_005375	MYB	v-myb myeloblastosis viral oncogene homolog (avian)
chr2_+_232573249	4.916		PTMA	prothymosin, alpha
chr1_-_36235422	4.848	NM_001190481 NM_022111	CLSPN	claspin
chr8_-_95907423	4.565	NM_057749	CCNE2	cyclin E2
chr19_+_4910339	4.303	NM_013282	UHRF1	ubiquitin-like with PHD and ring finger domains 1
chr13_-_41768533	4.281	NM_032138	KBTBD7	kelch repeat and BTB (POZ) domain containing 7
chr20_-_44563684	4.260		FLJ40606	uncharacterized LOC643549
chr15_+_41221530	4.127	NM_019074	DLL4	delta-like 4 (Drosophila)
chr16_+_67596309	4.105	NM_001191022 NM_006565	CTCF	CCCTC-binding factor (zinc finger protein)
chr6_-_52149541	4.089	NM_002388	MCM3	minichromosome maintenance complex component 3
chr6_-_52149472	4.060		MCM3	minichromosome maintenance complex component 3
chr7_+_94285736	4.011		PEG10	paternally expressed 10
chr15_+_40763159	3.996	NM_130468	CHST14	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr16_+_58426297	3.987	NM_001126129 NM_001126130 NM_022770	GINS3	GINS complex subunit 3 (Psf3 homolog)
chr6_-_52149516	3.917		MCM3	minichromosome maintenance complex component 3
chr7_+_94285676	3.904	NM_001172437 NM_001172438	PEG10	paternally expressed 10
chrX_-_131623994	3.902	NM_001170704	MBNL3	muscleblind-like 3 (Drosophila)
chr13_-_41768392	3.864		KBTBD7	kelch repeat and BTB (POZ) domain containing 7
chr5_+_36152221	3.863		SKP2	S-phase kinase-associated protein 2 (p45)
chr8_+_26435590	3.785		DPYSL2	dihydropyrimidinase-like 2
chr2_+_10262853	3.769	NM_001034	RRM2	ribonucleotide reductase M2
chr13_-_41706587	3.769	NM_152903	KBTBD6	kelch repeat and BTB (POZ) domain containing 6
chr11_-_19263144	3.662		E2F8	E2F transcription factor 8
chr5_-_101631965	3.644	NM_180991	SLCO4C1	solute carrier organic anion transporter family, member 4C1
chr5_+_36152142	3.619	NM_001243120 NM_005983 NM_032637	SKP2	S-phase kinase-associated protein 2 (p45)
chr8_+_26435466	3.573		DPYSL2	dihydropyrimidinase-like 2
chr13_+_114239047	3.548	NM_007111	TFDP1	transcription factor Dp-1
chr7_+_94285620	3.519	NM_001040152 NM_001184961 NM_001184962 NM_015068	PEG10	paternally expressed 10
chr2_+_10262694	3.493	NM_001165931	RRM2	ribonucleotide reductase M2
chr11_+_77850824	3.463		LOC100289388	uncharacterized LOC100289388
chr16_-_85722503	3.437		GINS2	GINS complex subunit 2 (Psf2 homolog)
chr16_-_85722587	3.415	NM_016095	GINS2	GINS complex subunit 2 (Psf2 homolog)
chr2_+_85766291	3.296		MAT2A	methionine adenosyltransferase II, alpha
chr4_+_178231013	3.268		NEIL3	nei endonuclease VIII-like 3 (E. coli)
chr10_-_21805715	3.266		C10orf140	chromosome 10 open reading frame 140
chr1_-_202679415	3.195	NM_177402	SYT2	synaptotagmin II
chr5_+_93954352	3.174	NM_032290	ANKRD32	ankyrin repeat domain 32
chr6_+_27114860	3.150	NM_080596	HIST1H2AH	histone cluster 1, H2ah
chr20_-_35724330	3.132		RBL1	retinoblastoma-like 1 (p107)
chr17_-_35293920	3.095
chr8_+_48873533	3.094		MCM4	minichromosome maintenance complex component 4
chr10_+_99473478	3.087		MARVELD1	MARVEL domain containing 1
chr4_+_178230979	3.083	NM_018248	NEIL3	nei endonuclease VIII-like 3 (E. coli)
chr20_-_44563573	3.055		FLJ40606	uncharacterized LOC643549
chr19_-_6502224	3.053	NM_006087	TUBB4A	tubulin, beta 4A class IVa
chr3_+_127317274	3.033		MCM2	minichromosome maintenance complex component 2
chr6_-_27775683	2.989	NM_003519	HIST1H2BL	histone cluster 1, H2bl
chr10_+_13203547	2.980	NM_018518 NM_182751	MCM10	minichromosome maintenance complex component 10
chr3_+_127317271	2.940		MCM2	minichromosome maintenance complex component 2
chr20_+_5891973	2.917	NM_001819	CHGB	chromogranin B (secretogranin 1)
chr10_-_53459309	2.913	NM_015235	CSTF2T	cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant
chr8_+_26435339	2.908	NM_001386	DPYSL2	dihydropyrimidinase-like 2
chr6_-_26250832	2.890	NM_021018	HIST1H3J HIST1H3F	histone cluster 1, H3j histone cluster 1, H3f
chr1_+_212209129	2.869		DTL	denticleless homolog (Drosophila)
chr7_-_44887697	2.864	NM_012412 NM_138635 NM_201436 NM_201516 NM_201517	H2AFV	H2A histone family, member V
chr10_+_99473456	2.823	NM_031484	MARVELD1	MARVEL domain containing 1
chr19_-_13030074	2.808	NM_001105578	SYCE2	synaptonemal complex central element protein 2
chr1_+_212208918	2.806	NM_016448	DTL	denticleless homolog (Drosophila)
chr4_-_146859960	2.800
chr12_+_70759974	2.738	NM_014505	KCNMB4	potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr8_+_48873446	2.737		MCM4	minichromosome maintenance complex component 4
chr3_+_127317212	2.726	NM_004526	MCM2	minichromosome maintenance complex component 2
chr17_-_56084514	2.718		SRSF1	serine/arginine-rich splicing factor 1
chr16_-_74401792	2.707
chr11_-_19262424	2.694	NM_024680	E2F8	E2F transcription factor 8
chr1_+_212209112	2.686		DTL	denticleless homolog (Drosophila)
chr6_+_31126114	2.650	NM_001077511 NM_007109	TCF19	transcription factor 19
chr2_+_174219537	2.635	NM_031942 NM_145810	CDCA7	cell division cycle associated 7
chr15_+_91260575	2.615	NM_000057	BLM	Bloom syndrome, RecQ helicase-like
chr11_-_118966175	2.615	NM_002105	H2AFX	H2A histone family, member X
chr6_-_116575170	2.607	NM_021648	TSPYL4	TSPY-like 4
chr12_+_109535377	2.587	NM_080911	UNG	uracil-DNA glycosylase
chr6_-_153304093	2.586	NM_012177	FBXO5	F-box protein 5
chr1_-_205719309	2.581
chr8_+_48873510	2.555		MCM4	minichromosome maintenance complex component 4
chr6_+_31126340	2.530		TCF19	transcription factor 19
chr22_+_35796104	2.528	NM_006739	MCM5	minichromosome maintenance complex component 5
chr1_+_26798961	2.518		HMGN2	high mobility group nucleosomal binding domain 2
chr3_-_44803095	2.517	NM_020696	KIAA1143	KIAA1143
chr10_-_25241504	2.481	NM_020200	PRTFDC1	phosphoribosyl transferase domain containing 1
chr5_+_126626455	2.458	NM_032446	MEGF10	multiple EGF-like-domains 10
chr1_-_32801606	2.441	NM_023009	MARCKSL1	MARCKS-like 1
chr16_+_87636492	2.433	NM_020655	JPH3	junctophilin 3
chr19_-_36705982	2.403	NM_001042474	ZNF565	zinc finger protein 565
chr1_-_205719340	2.403	NM_022731	NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr12_+_109535922	2.401	NM_003362	UNG	uracil-DNA glycosylase
chr11_-_118966103	2.401		H2AFX	H2A histone family, member X
chr1_-_23670743	2.385	NM_001102397 NM_001102398 NM_001102399 NM_005826	HNRNPR	heterogeneous nuclear ribonucleoprotein R
chr1_+_11714431	2.376	NM_183412	FBXO44	F-box protein 44
chr17_-_27949814	2.370		CORO6	coronin 6
chr3_-_169381417	2.344	NM_001205194 NM_004991	MECOM	MDS1 and EVI1 complex locus
chr9_+_86595636	2.335	NM_024945	RMI1	RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae)
chr22_+_20104810	2.331	NM_002882	RANBP1	RAN binding protein 1
chr17_-_56084571	2.330		SRSF1	serine/arginine-rich splicing factor 1
chr6_+_27775898	2.326	NM_003509	HIST1H2AI HIST1H2AM HIST1H3F	histone cluster 1, H2ai histone cluster 1, H2am histone cluster 1, H3f
chr1_+_78511747	2.316		GIPC2	GIPC PDZ domain containing family, member 2
chr22_+_20105145	2.309		RANBP1	RAN binding protein 1
chr10_-_73848263	2.304		SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr2_+_48010220	2.300	NM_000179	MSH6	mutS homolog 6 (E. coli)
chr17_+_38444134	2.291	NM_001254	CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr17_+_38444130	2.279		CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr8_-_120868034	2.275	NM_024094	DSCC1	defective in sister chromatid cohesion 1 homolog (S. cerevisiae)
chr20_-_35724401	2.262	NM_002895 NM_183404	RBL1	retinoblastoma-like 1 (p107)
chrX_-_119763804	2.262	NM_001011551 NM_152692	C1GALT1C1	C1GALT1-specific chaperone 1
chr2_+_172950207	2.237	NM_001038493 NM_178120	DLX1	distal-less homeobox 1
chr5_-_36876730	2.235		LOC646719	uncharacterized LOC646719
chr11_+_74303626	2.214	NM_006591	POLD3	polymerase (DNA-directed), delta 3, accessory subunit
chr22_+_20105095	2.195		RANBP1	RAN binding protein 1
chr2_+_233498206	2.195	NM_025202	EFHD1	EF-hand domain family, member D1
chr22_+_35796154	2.183		MCM5	minichromosome maintenance complex component 5
chr1_-_26185847	2.182	NM_024037	C1orf135	chromosome 1 open reading frame 135
chr3_-_14989399	2.182		LOC100505641	uncharacterized LOC100505641
chr5_-_79950348	2.178		DHFR	dihydrofolate reductase
chr3_-_107809754	2.141	NM_001777 NM_198793	CD47	CD47 molecule
chr14_+_85999464	2.139
chr10_-_13390189	2.138	NM_001195602 NM_001195604 NM_012247	SEPHS1	selenophosphate synthetase 1
chr9_+_116638544	2.133	NM_133374	ZNF618	zinc finger protein 618
chr13_+_114238978	2.125		TFDP1	transcription factor Dp-1
chr1_+_26798901	2.109	NM_005517	HMGN2	high mobility group nucleosomal binding domain 2
chr1_-_91487593	2.101		ZNF644	zinc finger protein 644
chr10_-_21785873	2.075		C10orf114	chromosome 10 open reading frame 114
chr2_+_47630246	2.069	NM_000251	MSH2	mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli)
chr5_-_126409171	2.068	NM_001164478 NM_001164479	C5orf63	chromosome 5 open reading frame 63
chr16_-_67281312	2.061		FHOD1	formin homology 2 domain containing 1
chr7_-_44887567	2.057		H2AFV	H2A histone family, member V
chr1_-_205719157	2.055		NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr1_-_26232643	2.053	NM_203401	STMN1	stathmin 1
chr7_-_44887663	2.046		H2AFV	H2A histone family, member V
chr1_-_91487543	2.037		ZNF644	zinc finger protein 644
chr17_+_7211260	2.030	NM_001143761	EIF5A	eukaryotic translation initiation factor 5A
chr14_-_74551159	2.028	NM_005589	ALDH6A1	aldehyde dehydrogenase 6 family, member A1
chr22_+_20105076	2.023		RANBP1	RAN binding protein 1
chr17_+_57642885	2.023	NM_001166301 NM_024612	DHX40	DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr6_+_52535874	2.012	NM_014051	TMEM14A	transmembrane protein 14A
chr15_+_56657615	2.010	NM_198524	TEX9	testis expressed 9
chr12_-_12849120	1.990	NM_006143	GPR19	G protein-coupled receptor 19
chr17_+_38444151	1.989		CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr1_-_205719273	1.954		NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr1_-_205719129	1.950		NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr3_-_148804122	1.950	NM_003071 NM_139048	HLTF	helicase-like transcription factor
chr2_-_47168902	1.943	NM_001171508 NM_001171511	MCFD2	multiple coagulation factor deficiency 2
chr19_+_45909466	1.929	NM_012099	CD3EAP	CD3e molecule, epsilon associated protein
chr22_+_20105068	1.916		RANBP1	RAN binding protein 1
chr7_-_44887620	1.915		H2AFV	H2A histone family, member V
chr1_-_54304107	1.909	NM_001168551 NM_018087	TMEM48	transmembrane protein 48
chr14_-_21852161	1.906		SUPT16H	suppressor of Ty 16 homolog (S. cerevisiae)
chr1_-_54303933	1.905		TMEM48	transmembrane protein 48
chr16_-_74401991	1.903		LOC283922	pyruvate dehydrogenase phosphatase regulatory subunit pseudogene
chr16_+_29817426	1.896		MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)
chr5_-_79950307	1.892		DHFR	dihydrofolate reductase
chr1_+_242011544	1.882		EXO1	exonuclease 1
chr6_+_41040713	1.881		NFYA	nuclear transcription factor Y, alpha
chr3_-_196230365	1.864	NM_152617	RNF168	ring finger protein 168
chr22_+_35796294	1.861		MCM5	minichromosome maintenance complex component 5
chr14_-_74551073	1.841		ALDH6A1	aldehyde dehydrogenase 6 family, member A1
chr6_+_132129195	1.838		ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1
chr12_-_133263988	1.837		POLE	polymerase (DNA directed), epsilon
chr1_-_205719078	1.808		NUCKS1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr10_+_115803805	1.808	NM_000684	ADRB1	adrenergic, beta-1-, receptor
chr14_+_50087400	1.794	NM_002408	MGAT2	mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr12_+_72666462	1.792	NM_013381	TRHDE	thyrotropin-releasing hormone degrading enzyme
chr15_-_66648991	1.781	NM_017858	TIPIN	TIMELESS interacting protein
chr1_+_178995004	1.776		FAM20B	family with sequence similarity 20, member B
chr16_-_4323000	1.774	NM_003223	TFAP4	transcription factor AP-4 (activating enhancer binding protein 4)
chr1_+_78511588	1.769	NM_017655	GIPC2	GIPC PDZ domain containing family, member 2
chr20_+_5931297	1.758	NM_032485 NM_182802	MCM8	minichromosome maintenance complex component 8
chr17_+_34890796	1.757
chr3_+_147127151	1.756	NM_003412	ZIC1	Zic family member 1
chr1_+_33722158	1.746	NM_152493	ZNF362	zinc finger protein 362
chr3_-_142682177	1.743	NM_198504	PAQR9	progestin and adipoQ receptor family member IX
chr20_+_25388328	1.729		GINS1	GINS complex subunit 1 (Psf1 homolog)
chr10_-_73848278	1.713		SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr10_-_13390018	1.703		SEPHS1	selenophosphate synthetase 1
chr19_+_30302861	1.695	NM_001238	CCNE1	cyclin E1
chr1_-_91487586	1.693		ZNF644	zinc finger protein 644
chr13_+_115079943	1.687	NM_001164144 NM_001164145 NM_032436	CHAMP1	chromosome alignment maintaining phosphoprotein 1
chr9_+_100745584	1.687		ANP32B	acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chrX_-_125300079	1.681	NM_001013628	DCAF12L2	DDB1 and CUL4 associated factor 12-like 2
chr10_-_21786186	1.678		C10orf114	chromosome 10 open reading frame 114
chr17_-_56084611	1.676		SRSF1	serine/arginine-rich splicing factor 1
chr20_-_60982334	1.665	NM_031215	CABLES2	Cdk5 and Abl enzyme substrate 2
chr11_+_65029312	1.665	NM_002689	POLA2	polymerase (DNA directed), alpha 2 (70kD subunit)
chr14_-_21852085	1.665		SUPT16H	suppressor of Ty 16 homolog (S. cerevisiae)

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
6.95	1.67e-27	GO:0006259	DNA metabolic process
13.79	3.81e-27	GO:0006260	DNA replication
20.68	1.77e-19	GO:0006261	DNA-dependent DNA replication
4.34	3.46e-19	GO:0007049	cell cycle
5.33	5.08e-19	GO:0022403	cell cycle phase
7.72	1.49e-16	GO:0051325	interphase
34.47	3.74e-16	GO:0006271	DNA strand elongation involved in DNA replication
4.53	4.65e-16	GO:0022402	cell cycle process
7.61	8.69e-16	GO:0051329	interphase of mitotic cell cycle
32.17	1.32e-15	GO:0022616	DNA strand elongation
5.11	2.52e-14	GO:0000278	mitotic cell cycle
10.91	5.51e-14	GO:0000082	G1/S transition of mitotic cell cycle
2.41	3.48e-13	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.62	7.15e-13	GO:0090304	nucleic acid metabolic process
11.91	1.48e-12	GO:0051320	S phase
34.47	2.68e-12	GO:0006270	DNA-dependent DNA replication initiation
6.19	3.14e-12	GO:0010564	regulation of cell cycle process
4.50	1.05e-11	GO:0051726	regulation of cell cycle
6.07	1.60e-11	GO:0006281	DNA repair
11.49	1.62e-11	GO:0000084	S phase of mitotic cell cycle
2.11	1.62e-10	GO:0006807	nitrogen compound metabolic process
2.13	1.87e-10	GO:0034641	cellular nitrogen compound metabolic process
2.73	4.09e-10	GO:0034645	cellular macromolecule biosynthetic process
7.16	4.42e-10	GO:0071156	regulation of cell cycle arrest
2.70	6.82e-10	GO:0009059	macromolecule biosynthetic process
4.54	1.50e-09	GO:0006974	response to DNA damage stimulus
7.10	1.80e-09	GO:0000075	cell cycle checkpoint
4.08	5.02e-09	GO:0051276	chromosome organization
7.92	4.39e-08	GO:0071103	DNA conformation change
2.21	5.35e-08	GO:0044249	cellular biosynthetic process
11.49	7.91e-08	GO:0000216	M/G1 transition of mitotic cell cycle
8.17	1.03e-07	GO:0006310	DNA recombination
2.14	1.37e-07	GO:0009058	biosynthetic process
27.57	1.79e-07	GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle
3.48	6.26e-07	GO:0065003	macromolecular complex assembly
8.62	7.70e-07	GO:0071824	protein-DNA complex subunit organization
3.19	9.42e-07	GO:0043933	macromolecular complex subunit organization
7.66	1.01e-06	GO:0006333	chromatin assembly or disassembly
9.24	1.31e-06	GO:0031497	chromatin assembly
8.79	2.47e-06	GO:0034728	nucleosome organization
1.85	3.67e-06	GO:0016043	cellular component organization
8.46	4.00e-06	GO:0065004	protein-DNA complex assembly
7.60	4.10e-06	GO:0006323	DNA packaging
25.40	5.13e-06	GO:0032201	telomere maintenance via semi-conservative replication
1.82	7.23e-06	GO:0071840	cellular component organization or biogenesis
34.47	7.24e-06	GO:0071897	DNA biosynthetic process
24.13	7.80e-06	GO:0000722	telomere maintenance via recombination
3.03	1.08e-05	GO:0033554	cellular response to stress
7.00	1.21e-05	GO:0051052	regulation of DNA metabolic process
2.69	2.97e-05	GO:0022607	cellular component assembly
2.28	3.57e-05	GO:0006996	organelle organization
12.17	4.12e-05	GO:0051053	negative regulation of DNA metabolic process
18.56	6.15e-05	GO:0006312	mitotic recombination
1.64	6.96e-05	GO:0044260	cellular macromolecule metabolic process
38.30	7.19e-05	GO:0002566	somatic diversification of immune receptors via somatic mutation
38.30	7.19e-05	GO:0016446	somatic hypermutation of immunoglobulin genes
8.25	8.44e-05	GO:0006334	nucleosome assembly
2.47	1.79e-04	GO:0044085	cellular component biogenesis
1.88	1.85e-04	GO:0071842	cellular component organization at cellular level
8.62	2.16e-04	GO:0006275	regulation of DNA replication
15.57	2.31e-04	GO:0010833	telomere maintenance via telomere lengthening
20.68	2.76e-04	GO:0006298	mismatch repair
20.68	2.76e-04	GO:2000104	negative regulation of DNA-dependent DNA replication
1.84	3.04e-04	GO:0071841	cellular component organization or biogenesis at cellular level
11.49	3.79e-04	GO:0000723	telomere maintenance
19.70	3.81e-04	GO:0002562	somatic diversification of immune receptors via germline recombination within a single locus
19.70	3.81e-04	GO:0016444	somatic cell DNA recombination
3.89	4.44e-04	GO:0034622	cellular macromolecular complex assembly
11.26	4.47e-04	GO:0032200	telomere organization
3.38	5.91e-04	GO:0034621	cellular macromolecular complex subunit organization
17.98	6.92e-04	GO:0090329	regulation of DNA-dependent DNA replication
12.70	1.02e-03	GO:0008156	negative regulation of DNA replication
16.55	1.19e-03	GO:0002200	somatic diversification of immune receptors
3.46	1.39e-03	GO:0000279	M phase
1.51	1.70e-03	GO:0043170	macromolecule metabolic process
21.54	2.30e-03	GO:0006297	nucleotide-excision repair, DNA gap filling
34.47	2.83e-03	GO:0000731	DNA synthesis involved in DNA repair
20.28	3.21e-03	GO:0016447	somatic recombination of immunoglobulin gene segments
6.33	3.89e-03	GO:0007126	meiosis
6.33	3.89e-03	GO:0051327	M phase of meiotic cell cycle
1.40	4.00e-03	GO:0044238	primary metabolic process
3.22	4.18e-03	GO:0006325	chromatin organization
6.27	4.23e-03	GO:0051321	meiotic cell cycle
12.17	8.08e-03	GO:0006284	base-excision repair
15.67	1.29e-02	GO:0016445	somatic diversification of immunoglobulins
25.07	1.29e-02	GO:0000076	DNA replication checkpoint
25.07	1.29e-02	GO:0032297	negative regulation of DNA-dependent DNA replication initiation
1.38	1.63e-02	GO:0044237	cellular metabolic process
1.68	2.08e-02	GO:0051171	regulation of nitrogen compound metabolic process
13.26	3.07e-02	GO:0002377	immunoglobulin production
1.67	3.35e-02	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
12.77	3.73e-02	GO:0002440	production of molecular mediator of immune response
5.49	3.73e-02	GO:0031570	DNA integrity checkpoint
19.70	3.78e-02	GO:0030174	regulation of DNA-dependent DNA replication initiation
1.18	4.40e-02	GO:0009987	cellular process
2.45	4.42e-02	GO:0071844	cellular component assembly at cellular level
2.57	4.53e-02	GO:0010558	negative regulation of macromolecule biosynthetic process

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.90	2.00e-17	GO:0005634	nucleus
5.27	5.65e-16	GO:0005694	chromosome
5.66	3.32e-15	GO:0044427	chromosomal part
2.59	2.20e-13	GO:0044428	nuclear part
1.49	3.15e-13	GO:0043231	intracellular membrane-bounded organelle
1.49	3.59e-13	GO:0043227	membrane-bounded organelle
3.15	8.19e-13	GO:0005654	nucleoplasm
2.73	1.02e-12	GO:0031981	nuclear lumen
1.40	2.57e-11	GO:0043229	intracellular organelle
1.40	3.18e-11	GO:0043226	organelle
2.39	5.87e-11	GO:0070013	intracellular organelle lumen
7.22	6.12e-11	GO:0000228	nuclear chromosome
1.71	1.15e-10	GO:0044446	intracellular organelle part
2.34	1.16e-10	GO:0031974	membrane-enclosed lumen
2.34	1.58e-10	GO:0043233	organelle lumen
1.68	3.58e-10	GO:0044422	organelle part
20.50	4.52e-10	GO:0005657	replication fork
7.71	8.33e-10	GO:0044454	nuclear chromosome part
10.16	1.37e-08	GO:0032993	protein-DNA complex
6.00	2.28e-08	GO:0000785	chromatin
1.25	1.46e-06	GO:0044424	intracellular part
21.94	2.82e-06	GO:0043596	nuclear replication fork
43.08	5.44e-06	GO:0042555	MCM complex
24.33	1.53e-05	GO:0030894	replisome
24.33	1.53e-05	GO:0043601	nuclear replisome
1.22	2.58e-05	GO:0005622	intracellular
1.77	2.30e-04	GO:0043228	non-membrane-bounded organelle
1.77	2.30e-04	GO:0043232	intracellular non-membrane-bounded organelle
9.19	3.72e-04	GO:0000786	nucleosome
1.58	1.99e-03	GO:0032991	macromolecular complex
2.55	2.72e-03	GO:0044451	nucleoplasm part
34.47	9.71e-03	GO:0005658	alpha DNA polymerase:primase complex
4.47	3.12e-02	GO:0000793	condensed chromosome
68.93	3.52e-02	GO:0032301	MutSalpha complex
1.53	4.09e-02	GO:0043234	protein complex

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
2.25	1.98e-09	GO:0003677	DNA binding
1.90	7.36e-08	GO:0003676	nucleic acid binding
5.22	9.54e-05	GO:0043566	structure-specific DNA binding
45.96	1.23e-04	GO:0032135	DNA insertion or deletion binding
39.39	2.83e-04	GO:0032404	mismatch repair complex binding
9.68	2.93e-04	GO:0003697	single-stranded DNA binding
4.82	6.01e-04	GO:0003682	chromatin binding
8.76	6.38e-04	GO:0008094	DNA-dependent ATPase activity
51.70	2.33e-03	GO:0032138	single base insertion or deletion binding
51.70	2.33e-03	GO:0032405	MutLalpha complex binding
22.98	3.78e-03	GO:0000217	DNA secondary structure binding
19.70	7.47e-03	GO:0030983	mismatched DNA binding
1.15	2.75e-02	GO:0005488	binding
4.60	2.94e-02	GO:0003690	double-stranded DNA binding
68.93	4.13e-02	GO:0004422	hypoxanthine phosphoribosyltransferase activity
68.93	4.13e-02	GO:0032143	single thymine insertion binding