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• Activity deltas table
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Motif ID: EN1,2.p2

Z-value: 1.484

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr6_+_17282931	3.407	NM_153020	RBM24	RNA binding motif protein 24
chr2_-_87248942	2.064	NM_002665 NM_001032392	PLGLB2 PLGLB1	plasminogen-like B2 plasminogen-like B1
chrM_+_10123	1.914
chr2_-_152590983	1.626	NM_001164507 NM_001164508 NM_004543	NEB	nebulin
chr2_-_145277879	1.365	NM_001171653 NM_014795	ZEB2	zinc finger E-box binding homeobox 2
chr17_-_63009302	1.295		GNA13	guanine nucleotide binding protein (G protein), alpha 13
chr11_+_62475113	1.259	NM_012202	GNG3	guanine nucleotide binding protein (G protein), gamma 3
chr9_+_33026482	1.202		DNAJA1	DnaJ (Hsp40) homolog, subfamily A, member 1
chr6_-_41703938	1.155	NM_001167827	TFEB	transcription factor EB
chr7_+_28452143	1.103	NM_182898	CREB5	cAMP responsive element binding protein 5
chr6_-_43595079	1.093		GTPBP2	GTP binding protein 2
chr6_-_43595046	1.073		GTPBP2	GTP binding protein 2
chr17_+_37821598	1.016	NM_003673	TCAP	titin-cap (telethonin)
chr19_+_41281281	1.012	NM_006533	MIA	melanoma inhibitory activity
chr8_-_87755880	1.004	NM_019098	CNGB3	cyclic nucleotide gated channel beta 3
chr15_+_71433787	0.905	NM_024817	THSD4	thrombospondin, type I, domain containing 4
chr13_+_42712177	0.874	NM_001204505 NM_001204506	DGKH	diacylglycerol kinase, eta
chr17_+_7384720	0.838	NM_001102614	SLC35G6	solute carrier family 35, member G6
chr19_+_49376488	0.809		PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr8_+_32579350	0.806	NM_001159996	NRG1	neuregulin 1
chr13_+_97874540	0.765	NM_144778 NM_207304	MBNL2	muscleblind-like 2 (Drosophila)
chr10_-_92680784	0.751		ANKRD1	ankyrin repeat domain 1 (cardiac muscle)
chr9_+_74920329	0.742
chr7_+_28530747	0.740		CREB5	cAMP responsive element binding protein 5
chr3_-_187452669	0.738	NM_001134738	BCL6	B-cell CLL/lymphoma 6
chr6_-_152702450	0.730		SYNE1	spectrin repeat containing, nuclear envelope 1
chr11_+_6220375	0.715	NM_001005178	OR52W1	olfactory receptor, family 52, subfamily W, member 1
chr11_-_124253238	0.700	NM_001005468	OR8B2	olfactory receptor, family 8, subfamily B, member 2
chr10_+_114154522	0.662		ACSL5	acyl-CoA synthetase long-chain family member 5
chr6_-_51952368	0.654	NM_138694 NM_170724	PKHD1	polycystic kidney and hepatic disease 1 (autosomal recessive)
chr6_-_30652434	0.646		PPP1R18	protein phosphatase 1, regulatory subunit 18
chr3_-_156878481	0.636	NM_020307	CCNL1	cyclin L1
chr9_-_34691135	0.620	NM_006274	CCL19	chemokine (C-C motif) ligand 19
chr15_-_80263460	0.615	NM_001114735 NM_004049	BCL2A1	BCL2-related protein A1
chr1_-_27732069	0.614		WASF2	WAS protein family, member 2
chr20_-_1309782	0.612		SDCBP2	syndecan binding protein (syntenin) 2
chr5_-_145483877	0.609	NM_001029869	PLAC8L1	PLAC8-like 1
chr9_+_131684561	0.591	NM_001100877	PHYHD1	phytanoyl-CoA dioxygenase domain containing 1
chr7_+_112120907	0.534	NM_001134468 NM_182597	C7orf53	chromosome 7 open reading frame 53
chr3_-_38992051	0.524	NM_014139	SCN11A	sodium channel, voltage-gated, type XI, alpha subunit
chr6_-_53530505	0.511	NM_001003760	KLHL31	kelch-like 31 (Drosophila)
chr3_+_28431986	0.507	NM_001040432	ZCWPW2	zinc finger, CW type with PWWP domain 2
chr1_+_16259046	0.493
chr1_+_153940345	0.488	NM_130898	CREB3L4	cAMP responsive element binding protein 3-like 4
chr20_-_30288094	0.485
chr6_+_155411422	0.473	NM_012454	TIAM2	T-cell lymphoma invasion and metastasis 2
chr12_-_10978867	0.470	NM_023921	TAS2R10	taste receptor, type 2, member 10
chr12_-_15865847	0.467		EPS8	epidermal growth factor receptor pathway substrate 8
chr6_+_26273143	0.466	NM_003525	HIST1H2BI	histone cluster 1, H2bi
chr15_+_42696957	0.459	NM_173089 NM_173090	CAPN3	calpain 3, (p94)
chr5_-_64777703	0.456	NM_197941	ADAMTS6	ADAM metallopeptidase with thrombospondin type 1 motif, 6
chrX_+_30248552	0.455	NM_002365	MAGEB3	melanoma antigen family B, 3
chr2_-_198540583	0.455	NM_144629	RFTN2	raftlin family member 2
chr10_-_65225605	0.454	NM_032776	JMJD1C	jumonji domain containing 1C
chr19_-_45908288	0.452	NM_006663	PPP1R13L	protein phosphatase 1, regulatory subunit 13 like
chr6_-_56507585	0.448	NM_001723 NM_015548	DST	dystonin
chr5_+_173472692	0.446	NM_015980	HMP19	HMP19 protein
chr12_-_48597074	0.444	NM_001004134	OR10AD1	olfactory receptor, family 10, subfamily AD, member 1
chr12_-_18243052	0.439	NM_024730	RERGL	RERG/RAS-like
chr10_+_114133838	0.438	NM_203379	ACSL5	acyl-CoA synthetase long-chain family member 5
chr5_+_68800003	0.432	NM_001205255	OCLN	occludin
chr15_+_93443559	0.430		CHD2	chromodomain helicase DNA binding protein 2
chr1_-_155774769	0.424		GON4L	gon-4-like (C. elegans)
chr10_+_114133775	0.421		ACSL5	acyl-CoA synthetase long-chain family member 5
chr7_-_44105162	0.420	NM_000290	PGAM2	phosphoglycerate mutase 2 (muscle)
chr3_+_187870808	0.419		LPP	LIM domain containing preferred translocation partner in lipoma
chr7_+_129906702	0.419	NM_001869	CPA2	carboxypeptidase A2 (pancreatic)
chr15_+_93443418	0.407	NM_001042572 NM_001271	CHD2	chromodomain helicase DNA binding protein 2
chr3_+_138066489	0.406	NM_001252091 NM_012219	MRAS	muscle RAS oncogene homolog
chr11_+_65266642	0.403
chr12_-_57674251	0.397
chr6_-_119470336	0.395	NM_001100411	FAM184A	family with sequence similarity 184, member A
chr4_-_88243994	0.395	NM_001136230 NM_178135	HSD17B13	hydroxysteroid (17-beta) dehydrogenase 13
chr1_+_113236679	0.394		MOV10	Mov10, Moloney leukemia virus 10, homolog (mouse)
chr1_-_26680620	0.382	NM_001039775	AIM1L	absent in melanoma 1-like
chr2_-_26541916	0.380	NM_001145168 NM_001145169	GPR113	G protein-coupled receptor 113
chr9_-_4152182	0.378	NM_152629	GLIS3	GLIS family zinc finger 3
chr11_-_26743545	0.375	NM_178498	SLC5A12	solute carrier family 5 (sodium/glucose cotransporter), member 12
chr5_-_139682657	0.373
chr9_-_96108695	0.373	NM_001098808	C9orf129	chromosome 9 open reading frame 129
chr10_+_70482210	0.373		CCAR1	cell division cycle and apoptosis regulator 1
chr15_+_86220267	0.370	NM_144767	AKAP13	A kinase (PRKA) anchor protein 13
chr10_+_99498233	0.368	NM_001002261	ZFYVE27	zinc finger, FYVE domain containing 27
chr7_+_128312345	0.361	NM_001012454 NM_001128926	FAM71F2	family with sequence similarity 71, member F2
chr22_+_25591072	0.359		KIAA1671	KIAA1671
chr6_-_31689455	0.355	NM_025261	LY6G6C	lymphocyte antigen 6 complex, locus G6C
chr8_+_11188494	0.354	NM_054028	SLC35G5	solute carrier family 35, member G5
chr19_+_41281081	0.354	NM_001202553	MIA	melanoma inhibitory activity
chr11_+_124439892	0.349	NM_001005194	OR8A1	olfactory receptor, family 8, subfamily A, member 1
chr1_-_42800902	0.347	NM_014947	FOXJ3	forkhead box J3
chr5_-_139682674	0.342		PFDN1	prefoldin subunit 1
chr1_-_42801529	0.341	NM_001198850	FOXJ3	forkhead box J3
chr14_-_77889231	0.341	NM_001113475	NOXRED1	NADP-dependent oxidoreductase domain containing 1
chr1_-_150587879	0.340
chr8_-_28347733	0.339	NM_172366	FBXO16 ZNF395	F-box protein 16 zinc finger protein 395
chr2_+_88047603	0.333	NM_002665 NM_001032392	PLGLB2 PLGLB1	plasminogen-like B2 plasminogen-like B1
chr4_-_74964996	0.332	NM_002089	CXCL2	chemokine (C-X-C motif) ligand 2
chr12_+_52056547	0.328	NM_001177984	SCN8A	sodium channel, voltage gated, type VIII, alpha subunit
chr1_+_26503973	0.327	NM_006314	CNKSR1	connector enhancer of kinase suppressor of Ras 1
chr4_-_54457723	0.326	NM_001126328	LNX1	ligand of numb-protein X 1
chr13_+_97874704	0.326		MBNL2	muscleblind-like 2 (Drosophila)
chr1_-_42800883	0.318	NM_001198852	FOXJ3	forkhead box J3
chr1_+_33231260	0.316		KIAA1522	KIAA1522
chr18_+_32398225	0.311	NM_001198942 NM_001198944 NM_032980 NM_032981	DTNA	dystrobrevin, alpha
chr17_-_40828441	0.310	NM_024927	PLEKHH3	pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr2_-_145277568	0.307		ZEB2	zinc finger E-box binding homeobox 2
chrX_+_69488154	0.306	NM_004312	ARR3	arrestin 3, retinal (X-arrestin)
chr1_-_150780705	0.303	NM_000396	CTSK	cathepsin K
chr10_+_104179570	0.303	NM_024326	FBXL15	F-box and leucine-rich repeat protein 15
chr1_+_67632168	0.301	NM_144701	IL23R	interleukin 23 receptor
chr4_+_71062241	0.297	NM_017855	ODAM	odontogenic, ameloblast asssociated
chr12_-_49999259	0.295	NM_032130	FAM186B	family with sequence similarity 186, member B
chr1_+_212797788	0.293	NM_153606	FAM71A	family with sequence similarity 71, member A
chr1_+_162351519	0.292	NM_001085375	C1orf226	chromosome 1 open reading frame 226
chr19_-_58067724	0.291	NM_001039654	ZNF550	zinc finger protein 550
chr15_-_77176191	0.291	NM_020843	SCAPER	S-phase cyclin A-associated protein in the ER
chr3_+_69812620	0.290	NM_001184967	MITF	microphthalmia-associated transcription factor
chr1_+_33231227	0.288	NM_001198972 NM_001198973	KIAA1522	KIAA1522
chr12_-_57630867	0.285		NDUFA4L2	NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr16_+_31085751	0.282		ZNF646	zinc finger protein 646
chr7_+_28338939	0.281	NM_182899	CREB5	cAMP responsive element binding protein 5
chr7_-_141673572	0.280	NM_176817	TAS2R38	taste receptor, type 2, member 38
chr1_-_42800623	0.279	NM_001198851	FOXJ3	forkhead box J3
chr6_-_31939658	0.278		DOM3Z	dom-3 homolog Z (C. elegans)
chr16_+_31085722	0.277	NM_014699	ZNF646	zinc finger protein 646
chr3_-_51996855	0.277	NM_033010	PCBP4	poly(rC) binding protein 4
chr12_-_57914287	0.277	NM_001195053 NM_001195054 NM_001195055 NM_001195056 NM_001195057 NM_004083	DDIT3	DNA-damage-inducible transcript 3
chr2_+_201170603	0.274	NM_015535	SPATS2L	spermatogenesis associated, serine-rich 2-like
chr20_+_44036940	0.273		DBNDD2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr16_+_31494438	0.271	NM_003041	SLC5A2	solute carrier family 5 (sodium/glucose cotransporter), member 2
chr11_-_6790187	0.270	NM_001004490	OR2AG2	olfactory receptor, family 2, subfamily AG, member 2
chr15_-_45003513	0.270
chr11_+_47290893	0.267	NM_130470	MADD	MAP-kinase activating death domain
chr17_-_62777621	0.265		LOC146880	Rho GTPase activating protein 27 pseudogene
chr11_+_6128913	0.262	NM_001005181	OR56B4	olfactory receptor, family 56, subfamily B, member 4
chr14_-_61191027	0.261		SIX4	SIX homeobox 4
chr11_-_89956531	0.260	NM_001144073 NM_012124	CHORDC1	cysteine and histidine-rich domain (CHORD) containing 1
chr11_-_83984230	0.259	NM_001142700	DLG2	discs, large homolog 2 (Drosophila)
chr3_+_52813936	0.257	NM_001166435 NM_001166436	ITIH1	inter-alpha-trypsin inhibitor heavy chain 1
chr12_+_7033625	0.257	NM_001007026	ATN1	atrophin 1
chr12_-_22089627	0.255	NM_005691 NM_020297	ABCC9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9
chr6_-_109775423	0.254		MICAL1	microtubule associated monoxygenase, calponin and LIM domain containing 1
chr4_+_103422479	0.254	NM_001165412 NM_003998	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr10_+_13142055	0.253	NM_001008211 NM_001008212 NM_001008213 NM_021980	OPTN	optineurin
chr9_-_34662629	0.251	NM_006664	CCL27	chemokine (C-C motif) ligand 27
chr11_-_117100551	0.249		PCSK7	proprotein convertase subtilisin/kexin type 7
chr7_+_112092112	0.249	NM_001197079	IFRD1	interferon-related developmental regulator 1
chr15_+_45021218	0.248		TRIM69	tripartite motif containing 69
chr20_+_54987167	0.248	NM_001164116 NM_001164114 NM_001164115 NM_020356	CASS4	Cas scaffolding protein family member 4
chr7_+_107110501	0.248	NM_005295	GPR22	G protein-coupled receptor 22
chr13_+_73356179	0.247	NM_006346	PIBF1	progesterone immunomodulatory binding factor 1
chr5_+_137673223	0.245	NM_001135647	FAM53C	family with sequence similarity 53, member C
chr1_-_145715561	0.243	NM_007053	CD160	CD160 molecule
chr5_-_139682680	0.243	NM_002622	PFDN1	prefoldin subunit 1
chr11_-_59633942	0.240	NM_001062	TCN1	transcobalamin I (vitamin B12 binding protein, R binder family)
chr11_-_5863126	0.240	NM_001005167	OR52E6	olfactory receptor, family 52, subfamily E, member 6
chr6_-_41006927	0.239	NM_173561	UNC5CL	unc-5 homolog C (C. elegans)-like
chr1_-_153919140	0.239	NM_014856	DENND4B	DENN/MADD domain containing 4B
chr7_-_120498128	0.236	NM_012338	TSPAN12	tetraspanin 12
chr17_-_27467395	0.236		MYO18A	myosin XVIIIA
chr1_+_150039815	0.233		VPS45	vacuolar protein sorting 45 homolog (S. cerevisiae)
chr10_-_62149487	0.232	NM_020987	ANK3	ankyrin 3, node of Ranvier (ankyrin G)
chr4_-_54457628	0.232		LNX1	ligand of numb-protein X 1
chr2_-_161056573	0.232	NM_000888	ITGB6	integrin, beta 6
chr3_-_184095927	0.232	NM_000460 NM_001177597 NM_001177598	THPO	thrombopoietin
chr4_+_91156181	0.231	NM_207491	FAM190A	family with sequence similarity 190, member A
chr4_+_74281884	0.231		ALB	albumin
chr7_-_20256942	0.231	NM_182762	MACC1	metastasis associated in colon cancer 1
chr21_-_34883620	0.230		GART	phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
chr19_-_46295785	0.230	NM_004943	DMWD	dystrophia myotonica, WD repeat containing
chr19_-_51472816	0.230	NM_002774	KLK6	kallikrein-related peptidase 6
chr11_+_5968576	0.230	NM_001003443	OR56A3	olfactory receptor, family 56, subfamily A, member 3
chrX_-_109683457	0.229	NM_001171689	AMMECR1	Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1
chr20_+_51589752	0.228		TSHZ2	teashirt zinc finger homeobox 2
chr13_+_50025687	0.228	NM_001160308	SETDB2	SET domain, bifurcated 2
chrX_-_76937157	0.227		ATRX	alpha thalassemia/mental retardation syndrome X-linked
chr3_-_114343791	0.226	NM_001164346	ZBTB20	zinc finger and BTB domain containing 20
chr4_+_88571453	0.224	NM_001079911 NM_004407	DMP1	dentin matrix acidic phosphoprotein 1
chr11_-_121986800	0.223	NM_001001786	BLID	BH3-like motif containing, cell death inducer
chr12_-_111893857	0.222
chr7_-_140302311	0.220	NM_015689	DENND2A	DENN/MADD domain containing 2A
chr2_-_158182154	0.220	NM_020711	ERMN	ermin, ERM-like protein
chrX_-_48327739	0.218		SLC38A5	solute carrier family 38, member 5
chr18_-_3219986	0.218	NM_003803 NM_019856	MYOM1	myomesin 1, 185kDa
chr12_+_75874512	0.218	NM_006851	GLIPR1	GLI pathogenesis-related 1
chrX_+_100805415	0.217	NM_016608	ARMCX1	armadillo repeat containing, X-linked 1
chr22_+_20861964	0.217		MED15	mediator complex subunit 15
chr19_-_56249739	0.217	NM_176820	NLRP9	NLR family, pyrin domain containing 9
chr1_+_59775749	0.215	NM_001244714	FGGY	FGGY carbohydrate kinase domain containing
chr9_-_34729463	0.212	NM_001141917	FAM205A	family with sequence similarity 205, member A
chr19_+_17326196	0.212		USE1	unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr9_+_116207010	0.212	NM_144488	RGS3	regulator of G-protein signaling 3
chr11_-_112131582	0.212	NM_001145024	C11orf34	chromosome 11 open reading frame 34
chr12_-_57504088	0.207	NM_001178079	STAT6	signal transducer and activator of transcription 6, interleukin-4 induced
chr8_+_92261515	0.206	NM_052832 NM_134266	SLC26A7	solute carrier family 26, member 7
chr16_-_1821503	0.205		NME3	non-metastatic cells 3, protein expressed in
chr6_-_79675672	0.205		PHIP	pleckstrin homology domain interacting protein
chr11_-_84028379	0.203	NM_001206769	DLG2	discs, large homolog 2 (Drosophila)
chr12_-_10542616	0.203	NM_007360	KLRK1	killer cell lectin-like receptor subfamily K, member 1
chr11_-_31832758	0.203		PAX6	paired box 6

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
13.16	1.83e-02	GO:0009792	embryo development ending in birth or egg hatching

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
66.29	1.26e-02	GO:0005834	heterotrimeric G-protein complex
59.32	1.57e-02	GO:0030018	Z disc
52.43	2.02e-02	GO:0031234	extrinsic to internal side of plasma membrane
46.98	2.51e-02	GO:0031674	I band
35.81	4.32e-02	GO:0019897	extrinsic to plasma membrane

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
450.39	2.05e-04	GO:0031702	type 1 angiotensin receptor binding
321.72	4.30e-04	GO:0031701	angiotensin receptor binding
16.46	1.77e-02	GO:0003924	GTPase activity
52.43	1.82e-02	GO:0008307	structural constituent of muscle