Motif ID: FEV.p2

Z-value: 2.236


Transcription factors associated with FEV.p2:

Gene SymbolEntrez IDGene Name
FEV 54738 FEV (ETS oncogene family)



Activity profile for motif FEV.p2.

activity profile for motif FEV.p2


Sorted Z-values histogram for motif FEV.p2

Sorted Z-values for motif FEV.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FEV.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_18535351 3.251 NM_001204145
NM_001204146
NM_014707
NM_178423
HDAC9



histone deacetylase 9



chr7_+_18548899 3.124 NM_001204147
NM_001204148
HDAC9

histone deacetylase 9

chr7_+_18548963 2.569 HDAC9
histone deacetylase 9
chr6_-_11382501 2.507 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr1_+_212738675 2.413 NM_001030287
ATF3
activating transcription factor 3
chr6_+_31515352 2.257 NM_001144961
NM_005007
NFKBIL1

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1

chr2_+_169659099 2.207 NM_001039724
NM_001171632
NM_052946
NOSTRIN


nitric oxide synthase trafficker


chr3_-_114343052 2.185 NM_001164347
ZBTB20
zinc finger and BTB domain containing 20
chr8_-_8175860 2.043 SGK223
homolog of rat pragma of Rnd2
chr17_+_43299277 1.941 NM_005892
FMNL1
formin-like 1
chr6_-_32160289 1.863 GPSM3
G-protein signaling modulator 3
chr7_+_18535817 1.790 NM_058176
NM_178425
HDAC9

histone deacetylase 9

chr11_+_46722564 1.719 NM_001184751
ZNF408
zinc finger protein 408
chr7_-_100882100 1.687 NM_001185080
CLDN15
claudin 15
chr1_-_150780705 1.659 NM_000396
CTSK
cathepsin K
chr11_-_1606480 1.646 NM_001005922
KRTAP5-1
keratin associated protein 5-1
chr1_-_221910801 1.577 NM_144728
DUSP10
dual specificity phosphatase 10
chr14_+_55034633 1.564 SAMD4A
sterile alpha motif domain containing 4A
chr3_+_119316694 1.560 NM_001206960
NM_001206961
NM_015900
PLA1A


phospholipase A1 member A


chr5_+_55149149 1.559 NM_001242636
NM_001242639
IL31RA

interleukin 31 receptor A

chr6_+_31515391 1.538 NFKBIL1
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
chr11_-_65667860 1.525 NM_005438
FOSL1
FOS-like antigen 1
chr19_+_13261272 1.521 NM_004907
IER2
immediate early response 2
chr15_-_71184611 1.476 NM_020147
THAP10
THAP domain containing 10
chr11_+_46722316 1.463 NM_024741
ZNF408
zinc finger protein 408
chr19_+_47759802 1.461 CCDC9
coiled-coil domain containing 9
chr10_+_114154522 1.458 ACSL5
acyl-CoA synthetase long-chain family member 5
chr19_+_41281281 1.442 NM_006533
MIA
melanoma inhibitory activity
chr11_+_2421983 1.438 TSSC4
tumor suppressing subtransferable candidate 4
chr14_+_65171149 1.430 NM_015549
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr2_+_28616360 1.419 FOSL2
FOS-like antigen 2
chr4_-_74964836 1.414 CXCL2
chemokine (C-X-C motif) ligand 2
chr19_+_47759730 1.407 NM_015603
CCDC9
coiled-coil domain containing 9
chr12_-_58159386 1.390 CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr9_+_130854127 1.387 NM_001006642
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr8_-_49833823 1.381 NM_003068
SNAI2
snail homolog 2 (Drosophila)
chr14_+_55034329 1.373 NM_001161576
NM_015589
SAMD4A

sterile alpha motif domain containing 4A

chr16_+_31085722 1.368 NM_014699
ZNF646
zinc finger protein 646
chr6_-_31620142 1.356 NM_001098534
BAG6
BCL2-associated athanogene 6
chr6_+_26156558 1.337 NM_005321
HIST1H1E
histone cluster 1, H1e
chr4_-_74904329 1.320 NM_002090
CXCL3
chemokine (C-X-C motif) ligand 3
chr6_-_11232900 1.314 NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr6_-_31620468 1.312 NM_001199697
NM_001199698
NM_004639
NM_080702
NM_080703
BAG6




BCL2-associated athanogene 6




chr19_+_45971249 1.298 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr14_+_65171243 1.297 PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr16_+_31085751 1.290 ZNF646
zinc finger protein 646
chr18_+_22040592 1.290 NM_001143828
NM_001160166
NM_021624
HRH4


histamine receptor H4


chr11_+_63974190 1.287 FERMT3
fermitin family member 3
chr22_-_40859423 1.285 MKL1
megakaryoblastic leukemia (translocation) 1
chr16_+_30710461 1.268 NM_006662
SRCAP
Snf2-related CREBBP activator protein
chr10_-_73533196 1.254 NM_022153
C10orf54
chromosome 10 open reading frame 54
chr19_-_1174201 1.244


chr2_+_28616346 1.229 FOSL2
FOS-like antigen 2
chr4_+_103422553 1.225 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr5_-_132272803 1.223


chr1_-_153931096 1.214 NM_181715
CRTC2
CREB regulated transcription coactivator 2
chr15_+_85359910 1.213 NM_020778
ALPK3
alpha-kinase 3
chr1_+_168545710 1.210 NM_002995
XCL1
chemokine (C motif) ligand 1
chr1_-_153930911 1.197 CRTC2
CREB regulated transcription coactivator 2
chr6_-_31620426 1.195 BAG6
BCL2-associated athanogene 6
chr6_-_31620384 1.192 BAG6
BCL2-associated athanogene 6
chr6_+_31553955 1.191 NM_205838
NM_205839
LST1

leukocyte specific transcript 1

chr2_-_74734498 1.187 PCGF1
polycomb group ring finger 1
chr3_+_150264514 1.174 NM_032025
EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr6_-_43595046 1.161 GTPBP2
GTP binding protein 2
chr11_-_6502563 1.155 NM_001242854
NM_001242855
NM_001242856
NM_012402
ARFIP2



ADP-ribosylation factor interacting protein 2



chr3_+_122334461 1.148 NM_152615
PARP15
poly (ADP-ribose) polymerase family, member 15
chr1_+_169337193 1.145 NM_003666
BLZF1
basic leucine zipper nuclear factor 1
chr3_+_152552735 1.139 NM_002563
P2RY1
purinergic receptor P2Y, G-protein coupled, 1
chr10_+_75545363 1.138 NM_001242487
NM_001242488
NM_015037
KIAA0913


KIAA0913


chr11_+_102188180 1.133 NM_001165
NM_182962
BIRC3

baculoviral IAP repeat containing 3

chr15_-_44092134 1.122 NM_001033517
SERINC4
serine incorporator 4
chr19_-_1174257 1.120 SBNO2
strawberry notch homolog 2 (Drosophila)
chr19_-_46285752 1.118 NM_001081560
NM_001081562
NM_004409
DMPK


dystrophia myotonica-protein kinase


chr16_+_67571980 1.118 FAM65A
family with sequence similarity 65, member A
chr3_-_50374749 1.117 RASSF1
Ras association (RalGDS/AF-6) domain family member 1
chr1_-_153931077 1.113 CRTC2
CREB regulated transcription coactivator 2
chr9_+_35560424 1.113 RUSC2
RUN and SH3 domain containing 2
chr1_+_156698270 1.112 RRNAD1
ribosomal RNA adenine dimethylase domain containing 1
chr4_+_74606222 1.112 NM_000584
IL8
interleukin 8
chr18_+_3453771 1.109 NM_173211
TGIF1
TGFB-induced factor homeobox 1
chr19_-_46285645 1.108 DMPK
dystrophia myotonica-protein kinase
chr10_+_31610063 1.107 NM_001128128
NM_001174094
ZEB1

zinc finger E-box binding homeobox 1

chr11_+_130029773 1.103 ST14
suppression of tumorigenicity 14 (colon carcinoma)
chr6_-_43595079 1.102 GTPBP2
GTP binding protein 2
chr19_-_1174263 1.097 NM_014963
SBNO2
strawberry notch homolog 2 (Drosophila)
chr1_-_35370983 1.095 NM_001080418
DLGAP3
discs, large (Drosophila) homolog-associated protein 3
chr6_-_33290678 1.077 NM_001141969
NM_001141970
NM_001350
DAXX


death-domain associated protein


chr12_-_123590045 1.071 PITPNM2
phosphatidylinositol transfer protein, membrane-associated 2
chr5_-_156536036 1.060 HAVCR2
hepatitis A virus cellular receptor 2
chrX_-_73834460 1.058 NM_016120
NM_183353
RLIM

ring finger protein, LIM domain interacting

chr11_+_46299585 1.041 CREB3L1
cAMP responsive element binding protein 3-like 1
chr5_+_172483285 1.041 NM_001168393
NM_001168394
NM_153607
C5orf41


chromosome 5 open reading frame 41


chr11_-_128894008 1.041 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr1_+_169337432 1.033 BLZF1
basic leucine zipper nuclear factor 1
chr1_+_156698250 1.033 NM_001142560
NM_015997
RRNAD1

ribosomal RNA adenine dimethylase domain containing 1

chr7_-_1595746 1.032 NM_001097620
TMEM184A
transmembrane protein 184A
chr3_-_121379701 1.022 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr1_-_38471170 1.013 NM_001243878
NM_004468
FHL3

four and a half LIM domains 3

chr6_-_31550065 1.012 NM_002341
NM_009588
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr19_-_4338750 1.012 NM_001013841
NM_017720
STAP2

signal transducing adaptor family member 2

chr11_+_65407591 1.010 NM_153253
SIPA1
signal-induced proliferation-associated 1
chr3_-_53925871 0.999 NM_021237
SELK
selenoprotein K
chr14_+_77924415 0.998 AHSA1
AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
chr5_-_43412417 0.998 NM_148672
CCL28
chemokine (C-C motif) ligand 28
chr19_-_55720812 0.989 NM_001161440
NM_002842
PTPRH

protein tyrosine phosphatase, receptor type, H

chr1_-_214724565 0.986 PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr15_+_93443559 0.985 CHD2
chromodomain helicase DNA binding protein 2
chr6_-_154677868 0.984 NM_001130700
NM_015553
IPCEF1

interaction protein for cytohesin exchange factors 1

chr6_-_153323787 0.983 MTRF1L
mitochondrial translational release factor 1-like
chr4_+_88571453 0.983 NM_001079911
NM_004407
DMP1

dentin matrix acidic phosphoprotein 1

chr7_-_99756275 0.982 NM_018275
C7orf43
chromosome 7 open reading frame 43
chr2_+_28615695 0.979 FOSL2
FOS-like antigen 2
chr15_+_93443418 0.974 NM_001042572
NM_001271
CHD2

chromodomain helicase DNA binding protein 2

chr4_+_186317837 0.971 NM_181726
ANKRD37
ankyrin repeat domain 37
chr4_+_103422822 0.970 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr17_-_62777621 0.968 LOC146880
Rho GTPase activating protein 27 pseudogene
chr1_+_155247186 0.963 NM_020897
HCN3
hyperpolarization activated cyclic nucleotide-gated potassium channel 3
chr3_-_53381533 0.958 NM_018403
DCP1A
DCP1 decapping enzyme homolog A (S. cerevisiae)
chr9_-_130186491 0.954


chrX_-_48937560 0.954 NM_001029896
WDR45
WD repeat domain 45
chr7_+_76178604 0.952 LOC100133091
uncharacterized LOC100133091
chr4_-_74964996 0.949 NM_002089
CXCL2
chemokine (C-X-C motif) ligand 2
chr9_-_14722669 0.949 NM_005454
CER1
cerberus 1, cysteine knot superfamily, homolog (Xenopus laevis)
chr2_+_37571752 0.945 NM_012413
QPCT
glutaminyl-peptide cyclotransferase
chr4_-_184243578 0.942 NM_001185149
CLDN24
claudin 24
chr19_-_56632600 0.942 ZNF787
zinc finger protein 787
chr6_+_26156552 0.930 HIST1H1E
histone cluster 1, H1e
chr7_+_157129659 0.926 NM_005494
NM_058246
DNAJB6

TMEM135
DnaJ (Hsp40) homolog, subfamily B, member 6

transmembrane protein 135
chr15_+_44092618 0.925 NM_001199885
NM_016400
C15orf63

chromosome 15 open reading frame 63

chr8_-_124665165 0.920 NM_001081675
KLHL38
kelch-like 38 (Drosophila)
chr2_+_28615771 0.917 NM_005253
FOSL2
FOS-like antigen 2
chr2_+_29038862 0.917 NM_001008779
SPDYA
speedy homolog A (Xenopus laevis)
chr14_+_77924367 0.913 NM_012111
AHSA1
AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
chr14_+_75745480 0.909 NM_005252
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr2_-_74734785 0.909 NM_032673
PCGF1
polycomb group ring finger 1
chr6_-_143266283 0.907 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr10_-_99160987 0.907 RRP12
ribosomal RNA processing 12 homolog (S. cerevisiae)
chr11_+_46299554 0.904 CREB3L1
cAMP responsive element binding protein 3-like 1
chr16_-_30366681 0.904 NM_006110
CD2BP2
CD2 (cytoplasmic tail) binding protein 2
chr19_+_15218141 0.903 NM_033025
SYDE1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr17_-_72968750 0.897


chr17_-_72968790 0.894 NM_030630
C17orf28
chromosome 17 open reading frame 28
chr2_+_28615668 0.890 FOSL2
FOS-like antigen 2
chr4_-_54930706 0.889 CHIC2
cysteine-rich hydrophobic domain 2
chr5_-_176037091 0.887 NM_052899
GPRIN1
G protein regulated inducer of neurite outgrowth 1
chr15_+_41136622 0.884 NM_001032367
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr17_-_38256548 0.879 NR1D1
nuclear receptor subfamily 1, group D, member 1
chr14_-_21567069 0.876 NM_001101672
ZNF219
zinc finger protein 219
chr19_-_11616395 0.873 ZNF653
zinc finger protein 653
chr10_-_99161013 0.872 NM_001145114
NM_015179
RRP12

ribosomal RNA processing 12 homolog (S. cerevisiae)

chr2_-_69870976 0.869 NM_014911
AAK1
AP2 associated kinase 1
chr20_-_44516237 0.867 NM_080608
SPATA25
spermatogenesis associated 25
chr4_+_103422730 0.860 NFKB1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr17_-_29641094 0.860 NM_006495
EVI2B
ecotropic viral integration site 2B
chr19_+_16296211 0.858 NM_014077
FAM32A
family with sequence similarity 32, member A
chr22_-_37640287 0.857 NM_002872
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr4_+_103422479 0.857 NM_001165412
NM_003998
NFKB1

nuclear factor of kappa light polypeptide gene enhancer in B-cells 1

chr14_+_102027687 0.857 NM_001362
DIO3
deiodinase, iodothyronine, type III
chr19_+_48248798 0.854 GLTSCR2
glioma tumor suppressor candidate region gene 2
chr9_-_4152182 0.852 NM_152629
GLIS3
GLIS family zinc finger 3
chr19_-_46285746 0.849 DMPK
dystrophia myotonica-protein kinase
chr17_+_62502860 0.849 CEP95
centrosomal protein 95kDa
chr1_+_68297985 0.846 LOC100289178
uncharacterized LOC100289178
chr19_-_59070324 0.846 NM_003969
UBE2M
ubiquitin-conjugating enzyme E2M
chr4_+_72897520 0.844 NM_004885
NPFFR2
neuropeptide FF receptor 2
chrX_-_48937457 0.844 WDR45
WD repeat domain 45
chr6_-_153323871 0.844 NM_001114184
NM_019041
MTRF1L

mitochondrial translational release factor 1-like

chr19_+_48248792 0.839 NM_015710
GLTSCR2
glioma tumor suppressor candidate region gene 2
chr11_-_72433379 0.836 NM_001135190
NM_015242
ARAP1

ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1

chr17_-_38256905 0.835 NM_021724
NR1D1
nuclear receptor subfamily 1, group D, member 1
chr19_-_6279797 0.835


chr1_+_182569427 0.834


chr7_-_99756329 0.834 C7orf43
chromosome 7 open reading frame 43
chr8_+_145582208 0.829 NM_001253816
NM_001253815
GPR172A

G protein-coupled receptor 172A

chr12_-_57914287 0.827 NM_001195053
NM_001195054
NM_001195055
NM_001195056
NM_001195057
NM_004083
DDIT3





DNA-damage-inducible transcript 3





chr1_+_201979689 0.826 NM_001114309
NM_004433
ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

chr15_-_80263460 0.826 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr10_+_75545296 0.822 KIAA0913
KIAA0913
chr14_+_23938883 0.818 NM_001042635
NM_015514
NGDN

neuroguidin, EIF4E binding protein

chr3_+_150264576 0.818 EIF2A
eukaryotic translation initiation factor 2A, 65kDa
chr6_-_108582307 0.817 NM_003795
NM_152827
SNX3

sorting nexin 3

chr4_-_54930466 0.816 CHIC2
cysteine-rich hydrophobic domain 2
chr11_+_47290893 0.815 NM_130470
MADD
MAP-kinase activating death domain
chr12_+_7053180 0.815 NM_138425
C12orf57
chromosome 12 open reading frame 57
chr7_+_92076762 0.814 NM_021167
GATAD1
GATA zinc finger domain containing 1
chr1_-_154946830 0.813 SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr7_-_16505292 0.811 NM_015464
SOSTDC1
sclerostin domain containing 1
chr11_+_61129831 0.808 TMEM138
transmembrane protein 138
chr4_+_110736911 0.808 GAR1
GAR1 ribonucleoprotein homolog (yeast)
chr14_+_67999915 0.806 NM_020715
PLEKHH1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr16_+_30773619 0.806 RNF40
ring finger protein 40
chr17_+_16318848 0.806 NM_016113
TRPV2
transient receptor potential cation channel, subfamily V, member 2
chr9_+_139971938 0.803 NM_207309
UAP1L1
UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr6_-_31648140 0.803 NM_025262
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr8_-_79717540 0.803 NM_000880
NM_001199886
NM_001199887
NM_001199888
IL7



interleukin 7



chr21_+_30517897 0.801 C21orf7
chromosome 21 open reading frame 7
chr2_+_148778573 0.800 NM_018328
MBD5
methyl-CpG binding domain protein 5
chr8_-_42234562 0.798 NM_014420
DKK4
dickkopf homolog 4 (Xenopus laevis)
chr1_-_156542320 0.796 NM_178229
IQGAP3
IQ motif containing GTPase activating protein 3

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
19.59 4.41e-03 GO:0008009 chemokine activity
17.67 6.64e-03 GO:0042379 chemokine receptor binding
4.96 1.76e-02 GO:0003712 transcription cofactor activity
4.95 1.79e-02 GO:0000988 protein binding transcription factor activity
4.95 1.79e-02 GO:0000989 transcription factor binding transcription factor activity
7.78 4.00e-02 GO:0003714 transcription corepressor activity