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Motif ID: IRF1,2,7.p3

Z-value: 1.499

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr10_+_91152321	3.123	NM_001548	IFIT1	interferon-induced protein with tetratricopeptide repeats 1
chr22_+_36044412	2.024	NM_030641	APOL6	apolipoprotein L, 6
chr3_-_172241060	2.000	NM_001190943 NM_001190942 NM_003810	TNFSF10	tumor necrosis factor (ligand) superfamily, member 10
chr10_+_91087601	1.693	NM_001549	IFIT3	interferon-induced protein with tetratricopeptide repeats 3
chr6_+_26440699	1.535	NM_001242803 NM_006994 NM_197974	BTN3A3	butyrophilin, subfamily 3, member A3
chr12_+_25205488	1.485		LRMP	lymphoid-restricted membrane protein
chr1_+_948846	1.416	NM_005101	ISG15	ISG15 ubiquitin-like modifier
chr5_-_95158365	1.325		GLRX	glutaredoxin (thioltransferase)
chr2_-_231084600	1.281	NM_004509 NM_004510 NM_080424	SP110	SP110 nuclear body protein
chr1_+_79086087	1.134	NM_006820	IFI44L	interferon-induced protein 44-like
chr2_-_152146373	1.125	NM_004688	NMI	N-myc (and STAT) interactor
chr10_+_91092238	1.101	NM_001031683	IFIT3	interferon-induced protein with tetratricopeptide repeats 3
chr22_+_36044475	1.092		APOL6	apolipoprotein L, 6
chr22_-_36635552	1.077		APOL2	apolipoprotein L, 2
chr6_+_26402464	1.076	NM_001145008 NM_001145009 NM_007048 NM_194441	BTN3A1	butyrophilin, subfamily 3, member A1
chr5_-_95158465	1.050	NM_001118890 NM_001243658 NM_001243659 NM_002064	GLRX	glutaredoxin (thioltransferase)
chr22_+_18632841	1.041		USP18	ubiquitin specific peptidase 18
chr8_-_23540401	0.983	NM_006167	NKX3-1	NK3 homeobox 1
chr6_+_116782555	0.912	NM_001010919	FAM26F	family with sequence similarity 26, member F
chr5_+_140739589	0.892	NM_018923 NM_032096	PCDHGB2	protocadherin gamma subfamily B, 2
chr10_+_91061705	0.859	NM_001547	IFIT2	interferon-induced protein with tetratricopeptide repeats 2
chr9_+_74764266	0.831	NM_001242505 NM_001242506 NM_004293	GDA	guanine deaminase
chr19_+_10196972	0.831		C19orf66	chromosome 19 open reading frame 66
chr11_-_4414887	0.810	NM_003141	TRIM21	tripartite motif containing 21
chr12_+_53442972	0.777		TENC1	tensin like C1 domain containing phosphatase (tensin 2)
chr6_+_26365397	0.745	NM_001197247 NM_001197249 NM_007047 NM_001197248	BTN3A2	butyrophilin, subfamily 3, member A2
chr11_-_114271052	0.729	NM_019021	C11orf71	chromosome 11 open reading frame 71
chr12_+_25205180	0.719	NM_001204126 NM_001204127 NM_006152	LRMP	lymphoid-restricted membrane protein
chr9_+_74764382	0.707		GDA	guanine deaminase
chr1_-_148176392	0.706
chr1_+_150480584	0.700		ECM1	extracellular matrix protein 1
chr2_-_152146133	0.690		NMI	N-myc (and STAT) interactor
chr19_+_10196757	0.686	NM_018381	C19orf66	chromosome 19 open reading frame 66
chr10_-_102279590	0.684	NM_015490	SEC31B	SEC31 homolog B (S. cerevisiae)
chr1_+_150480486	0.682	NM_001202858 NM_004425 NM_022664	ECM1	extracellular matrix protein 1
chr20_-_5100443	0.664	NM_182649	PCNA	proliferating cell nuclear antigen
chr6_+_26087447	0.645	NM_000410 NM_139003 NM_139004 NM_139006 NM_139007 NM_139008 NM_139009 NM_139010 NM_139011	HFE	hemochromatosis
chr6_+_49518112	0.625	NM_001145652	C6orf141	chromosome 6 open reading frame 141
chr5_-_111093251	0.622	NM_001142479 NM_001142480 NM_001142478	C5orf13	chromosome 5 open reading frame 13
chr19_+_10197023	0.615		C19orf66	chromosome 19 open reading frame 66
chr6_+_3259134	0.612	NM_001128591 NM_001128592 NM_001135750	PSMG4	proteasome (prosome, macropain) assembly chaperone 4
chr22_-_36635666	0.608	NM_030882	APOL2	apolipoprotein L, 2
chr17_-_40264687	0.599	NM_024119	DHX58	DEXH (Asp-Glu-X-His) box polypeptide 58
chr16_-_11350038	0.594	NM_003745	SOCS1	suppressor of cytokine signaling 1
chr9_+_74764417	0.593		GDA	guanine deaminase
chr13_+_39612440	0.586	NM_001012754 NM_001017370	NHLRC3	NHL repeat containing 3
chrX_+_38211735	0.584	NM_000531	OTC	ornithine carbamoyltransferase
chrX_-_100603673	0.572	NM_001145951	TIMM8A	translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr1_+_156030965	0.570	NM_020387	RAB25	RAB25, member RAS oncogene family
chr6_-_26197477	0.566		HIST1H3D	histone cluster 1, H3d
chr3_+_118892363	0.557	NM_006952	UPK1B	uroplakin 1B
chr6_+_112375277	0.555	NM_003880 NM_198239	WISP3	WNT1 inducible signaling pathway protein 3
chr22_-_22874597	0.554	NM_080740	ZNF280A	zinc finger protein 280A
chrX_-_100603956	0.551	NM_004085	TIMM8A	translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr21_+_42733916	0.536	NM_002463	LOC100131190 MX2	uncharacterized LOC100131190 myxovirus (influenza virus) resistance 2 (mouse)
chr6_-_87804773	0.535	NM_000735 NM_001252383	CGA	glycoprotein hormones, alpha polypeptide
chr5_-_35118223	0.528	NM_001204314 NM_001204315 NM_001204316 NM_001204317 NM_001204318	PRLR	prolactin receptor
chr9_-_100881515	0.523		TRIM14	tripartite motif containing 14
chr2_+_88047603	0.508	NM_002665 NM_001032392	PLGLB2 PLGLB1	plasminogen-like B2 plasminogen-like B1
chr5_+_140579182	0.501	NM_018931	PCDHB11	protocadherin beta 11
chr19_-_43032525	0.496	NM_001024912 NM_001184813 NM_001184815 NM_001184816 NM_001205344 NM_001712	CEACAM1	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
chr1_+_118148506	0.487	NM_017709	FAM46C	family with sequence similarity 46, member C
chr3_+_122399665	0.482	NM_017554	PARP14	poly (ADP-ribose) polymerase family, member 14
chrX_+_71364033	0.482	NM_207422	FLJ44635	TPT1-like protein
chr17_-_43339433	0.482	NM_152343	C17orf46	chromosome 17 open reading frame 46
chr8_+_27631902	0.478	NM_001017420	ESCO2	establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr16_+_66968360	0.474		CES2	carboxylesterase 2
chr5_+_36606667	0.470		SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr13_+_50069745	0.469	NM_001040443	PHF11	PHD finger protein 11
chr9_-_115818967	0.465	NM_003408	ZFP37	zinc finger protein 37 homolog (mouse)
chr1_-_23857284	0.465		E2F2	E2F transcription factor 2
chr3_-_122283077	0.462	NM_001146102 NM_001146105 NM_001146104 NM_001146106	PARP9	poly (ADP-ribose) polymerase family, member 9
chr11_+_124933197	0.461		SLC37A2	solute carrier family 37 (glycerol-3-phosphate transporter), member 2
chr6_-_133119625	0.461	NM_052831	C6orf192	chromosome 6 open reading frame 192
chr5_+_42565963	0.458	NM_001242460 NM_001242461 NM_001242462	GHR	growth hormone receptor
chrX_-_105282714	0.456	NM_000354	SERPINA7	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr8_+_132916376	0.447		EFR3A	EFR3 homolog A (S. cerevisiae)
chr3_-_123339178	0.443		MYLK	myosin light chain kinase
chr22_-_36635999	0.438	NM_145637	APOL2	apolipoprotein L, 2
chr5_+_140174443	0.438	NM_018905 NM_031495	PCDHA2	protocadherin alpha 2
chr8_+_132916383	0.434		EFR3A	EFR3 homolog A (S. cerevisiae)
chr10_+_5005685	0.434		AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr3_-_123339423	0.434	NM_053031 NM_053032	MYLK	myosin light chain kinase
chr4_-_156874993	0.432	NM_001334	CTSO	cathepsin O
chr15_-_89456549	0.429		MFGE8	milk fat globule-EGF factor 8 protein
chr17_+_46908371	0.422	NM_005831	CALCOCO2	calcium binding and coiled-coil domain 2
chr10_-_5045967	0.421	NM_001135241	AKR1C2	aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chr3_+_46448678	0.418	NM_003965 NM_001130910	CCRL2	chemokine (C-C motif) receptor-like 2
chr6_+_31913708	0.418	NM_001710	CFB	complement factor B
chr8_+_132916405	0.416
chr20_-_45976626	0.415		ZMYND8	zinc finger, MYND-type containing 8
chr9_-_100881462	0.415	NM_014788 NM_033219 NM_033220	TRIM14	tripartite motif containing 14
chr1_-_47695442	0.415	NM_003189	TAL1	T-cell acute lymphocytic leukemia 1
chr9_-_95298251	0.414	NM_001197295 NM_001197296 NM_001393	ECM2	extracellular matrix protein 2, female organ and adipocyte specific
chr7_+_93551015	0.410	NM_004126	GNG11	guanine nucleotide binding protein (G protein), gamma 11
chr18_-_48346297	0.410	NM_001127175 NM_001127176 NM_031939	MRO	maestro
chr16_+_66968319	0.409	NM_003869 NM_198061	CES2	carboxylesterase 2
chr15_-_89456592	0.408	NM_001114614 NM_005928	MFGE8	milk fat globule-EGF factor 8 protein
chr3_-_122283423	0.407	NM_001146103 NM_031458	PARP9	poly (ADP-ribose) polymerase family, member 9
chr14_-_70883680	0.404	NM_001202547 NM_001202548 NM_001202549 NM_018373	SYNJ2BP-COX16 SYNJ2BP	SYNJ2BP-COX16 readthrough synaptojanin 2 binding protein
chr11_+_72983246	0.402	NM_004154	P2RY6	pyrimidinergic receptor P2Y, G-protein coupled, 6
chr2_-_101767714	0.399	NM_001102426	TBC1D8	TBC1 domain family, member 8 (with GRAM domain)
chr7_+_105603656	0.396	NM_152750	CDHR3	cadherin-related family member 3
chr9_-_73483933	0.396	NM_001007470 NM_020952 NM_024971 NM_206944 NM_206945 NM_206946 NM_206947 NM_206948	TRPM3	transient receptor potential cation channel, subfamily M, member 3
chr16_-_75529278	0.394
chr16_+_66968365	0.394		CES2	carboxylesterase 2
chr2_-_175629140	0.393	NM_000079 NM_001039523	CHRNA1	cholinergic receptor, nicotinic, alpha 1 (muscle)
chr21_+_34144410	0.392		C21orf49	chromosome 21 open reading frame 49
chr5_+_96212167	0.390		ERAP2	endoplasmic reticulum aminopeptidase 2
chr9_+_74764354	0.385		GDA	guanine deaminase
chr15_+_78832787	0.385		PSMA4	proteasome (prosome, macropain) subunit, alpha type, 4
chr3_-_196230365	0.382	NM_152617	RNF168	ring finger protein 168
chr10_+_82173574	0.380	NM_001243778 NM_001243782	C10orf58	chromosome 10 open reading frame 58
chr10_+_5005601	0.378		AKR1C1 AKR1C3	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase) aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr18_-_65182507	0.374		DSEL	dermatan sulfate epimerase-like
chr15_+_78832746	0.372	NM_001102667 NM_001102668 NM_002789	PSMA4	proteasome (prosome, macropain) subunit, alpha type, 4
chr16_+_66968390	0.372		CES2	carboxylesterase 2
chr8_-_17752847	0.370	NM_147203 NM_201553 NM_004467 NM_201552	FGL1	fibrinogen-like 1
chr19_-_12992140	0.369		DNASE2	deoxyribonuclease II, lysosomal
chr1_-_154580677	0.365	NM_001111 NM_015840 NM_015841	ADAR	adenosine deaminase, RNA-specific
chr1_-_161039745	0.365	NM_001025598 NM_181720	ARHGAP30	Rho GTPase activating protein 30
chr10_+_91174303	0.361	NM_012420	IFIT5	interferon-induced protein with tetratricopeptide repeats 5
chr1_-_24469571	0.361	NM_021258	IL22RA1	interleukin 22 receptor, alpha 1
chr6_-_121655606	0.355	NM_152730	C6orf170	chromosome 6 open reading frame 170
chr1_+_229440128	0.350	NM_006542	SPHAR	S-phase response (cyclin related)
chr9_+_74764394	0.349		GDA	guanine deaminase
chr21_+_45177862	0.347		PDXK	pyridoxal (pyridoxine, vitamin B6) kinase
chr22_+_21128378	0.345	NM_000185	SERPIND1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr11_+_32112607	0.344		RCN1	reticulocalbin 1, EF-hand calcium binding domain
chr16_-_67970734	0.343	NM_002801	PSMB10	proteasome (prosome, macropain) subunit, beta type, 10
chr11_-_18343670	0.342	NM_007216 NM_181507 NM_181508	HPS5	Hermansky-Pudlak syndrome 5
chr1_-_57285368	0.340	NM_001004303	C1orf168	chromosome 1 open reading frame 168
chr12_+_98909414	0.335		TMPO	thymopoietin
chr2_-_152118258	0.335	NM_198557	RBM43	RNA binding motif protein 43
chrX_+_100878101	0.334	NM_016607 NM_177947	ARMCX3	armadillo repeat containing, X-linked 3
chr8_+_132916339	0.333	NM_015137	EFR3A	EFR3 homolog A (S. cerevisiae)
chr6_+_52529157	0.333		LOC730101	uncharacterized LOC730101
chr11_+_124933007	0.331	NM_001145290 NM_198277	SLC37A2	solute carrier family 37 (glycerol-3-phosphate transporter), member 2
chrX_+_119384490	0.330	NM_006777 NM_001184742	ZBTB33	zinc finger and BTB domain containing 33
chr1_-_154580632	0.328		ADAR	adenosine deaminase, RNA-specific
chr2_+_61389628	0.327	NM_001143959	C2orf74	chromosome 2 open reading frame 74
chr12_+_6561176	0.327	NM_018009	TAPBPL	TAP binding protein-like
chr2_-_21230572	0.327		APOB	apolipoprotein B (including Ag(x) antigen)
chr2_+_179278371	0.327
chr1_-_154580481	0.325		ADAR	adenosine deaminase, RNA-specific
chr10_+_97515408	0.323	NM_001164178 NM_001164181 NM_001164179 NM_001164182 NM_001164183 NM_001776	ENTPD1	ectonucleoside triphosphate diphosphohydrolase 1
chr6_+_131456825	0.321	NM_016377	AKAP7	A kinase (PRKA) anchor protein 7
chr2_-_142889269	0.321	NM_018557	LRP1B	low density lipoprotein receptor-related protein 1B
chr10_-_14996008	0.318	NM_001033855 NM_001033857 NM_001033858 NM_022487	DCLRE1C	DNA cross-link repair 1C
chr2_+_132480063	0.318	NM_013310	C2orf27A	chromosome 2 open reading frame 27A
chr13_+_53216564	0.318		HNRNPA1L2	heterogeneous nuclear ribonucleoprotein A1-like 2
chr11_-_115375065	0.317	NM_001098517 NM_014333	CADM1	cell adhesion molecule 1
chr11_-_57335080	0.316	NM_004223	UBE2L6	ubiquitin-conjugating enzyme E2L 6
chr18_-_55253785	0.312	NM_000140 NM_001012515	FECH	ferrochelatase
chr6_+_15246299	0.311	NM_004973	JARID2	jumonji, AT rich interactive domain 2
chr7_+_12250818	0.310	NM_001134232 NM_018374	TMEM106B	transmembrane protein 106B
chr10_+_5005453	0.310	NM_001353	AKR1C1	aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr3_-_160822625	0.309	NM_033169 NM_001038628 NM_003781 NM_033167 NM_033168	B3GALNT1	beta-1,3-N-acetylgalactosaminyltransferase 1 (globoside blood group)
chr3_-_100712248	0.308	NM_015429	ABI3BP	ABI family, member 3 (NESH) binding protein
chr11_+_28129797	0.307	NM_001113528 NM_152636	METTL15	methyltransferase like 15
chr8_+_18079176	0.307	NM_001160174	NAT1	N-acetyltransferase 1 (arylamine N-acetyltransferase)
chr3_+_122044010	0.306	NM_005213	CSTA	cystatin A (stefin A)
chr22_+_18632704	0.304	NM_017414	USP18	ubiquitin specific peptidase 18
chr4_+_77135192	0.302	NM_001242936	FAM47E	family with sequence similarity 47, member E
chr2_+_85811530	0.301	NM_006634	VAMP5	vesicle-associated membrane protein 5 (myobrevin)
chr14_-_60097314	0.300		RTN1	reticulon 1
chr11_-_47270178	0.300		ACP2	acid phosphatase 2, lysosomal
chr6_-_31239489	0.299		HLA-B HLA-C	major histocompatibility complex, class I, B major histocompatibility complex, class I, C
chr1_-_146644045	0.297	NM_005399	PRKAB2	protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr9_-_123812535	0.296	NM_001735	C5	complement component 5
chr8_+_75896707	0.295	NM_031461	CRISPLD1	cysteine-rich secretory protein LCCL domain containing 1
chr4_-_77134948	0.294		SCARB2	scavenger receptor class B, member 2
chr14_-_95608054	0.293	NM_030621	DICER1	dicer 1, ribonuclease type III
chr10_+_101542554	0.292		ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr4_-_53525316	0.291	NM_022832	USP46	ubiquitin specific peptidase 46
chrX_+_146993450	0.290	NM_001185075 NM_001185076 NM_001185081 NM_001185082 NM_002024	FMR1	fragile X mental retardation 1
chr16_-_3422282	0.289	NM_001190476	MTRNR2L4	MT-RNR2-like 4
chr1_+_179051111	0.289	NM_022371	TOR3A	torsin family 3, member A
chrX_+_146993663	0.288
chr6_-_32806545	0.288	NM_000544 NM_018833	TAP2	transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr9_+_79056581	0.288	NM_001097634	GCNT1	glucosaminyl (N-acetyl) transferase 1, core 2
chr2_-_77749335	0.287	NM_001134745 NM_024993	LRRTM4	leucine rich repeat transmembrane neuronal 4
chr1_+_19923457	0.287	NM_001204088 NM_001204089 NM_001032363 NM_001204082 NM_001204083	C1orf151-NBL1 MINOS1	C1orf151-NBL1 readthrough mitochondrial inner membrane organizing system 1
chrX_+_30261847	0.286	NM_002363 NM_177415	MAGEB1	melanoma antigen family B, 1
chr8_+_9911797	0.284	NM_001135670 NM_012331	MSRA	methionine sulfoxide reductase A
chr17_-_71088831	0.284		SLC39A11	solute carrier family 39 (metal ion transporter), member 11
chr17_-_71088832	0.282	NM_001159770 NM_139177	SLC39A11	solute carrier family 39 (metal ion transporter), member 11
chr1_-_168106727	0.282		GPR161	G protein-coupled receptor 161
chr1_+_64058891	0.282	NM_002633	PGM1	phosphoglucomutase 1
chr5_-_96143573	0.281		ERAP1	endoplasmic reticulum aminopeptidase 1
chr16_-_21289637	0.280		CRYM	crystallin, mu
chr12_+_7055753	0.279		PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr19_+_18284631	0.279		IFI30	interferon, gamma-inducible protein 30
chrX_+_77166223	0.277		ATP7A	ATPase, Cu++ transporting, alpha polypeptide
chr12_-_10022457	0.277	NM_005127	CLEC2B	C-type lectin domain family 2, member B
chr4_-_77134754	0.276		SCARB2	scavenger receptor class B, member 2
chr3_+_132316080	0.275	NM_016557	CCRL1	chemokine (C-C motif) receptor-like 1
chr1_+_179262936	0.274		SOAT1	sterol O-acyltransferase 1
chr16_-_67970651	0.272		PSMB10	proteasome (prosome, macropain) subunit, beta type, 10
chr5_+_36606456	0.272	NM_001166696 NM_004172	SLC1A3	solute carrier family 1 (glial high affinity glutamate transporter), member 3

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
72.70	1.34e-05	GO:0060337	type I interferon-mediated signaling pathway
72.70	1.34e-05	GO:0071357	cellular response to type I interferon
71.55	1.43e-05	GO:0034340	response to type I interferon
9.99	8.07e-04	GO:0006955	immune response
24.54	1.04e-03	GO:0019221	cytokine-mediated signaling pathway
9.21	1.29e-03	GO:0006952	defense response
22.14	1.57e-03	GO:0071345	cellular response to cytokine stimulus
15.98	5.63e-03	GO:0034097	response to cytokine stimulus
13.20	1.19e-02	GO:0045087	innate immune response
6.13	1.30e-02	GO:0002376	immune system process

Nothing significant found in compartment category.

Nothing significant found in function category.