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• Activity deltas table
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• Motifs sorted by significance (text)
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Motif ID: LEF1_TCF7_TCF7L1,2.p2

Z-value: 1.581

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr10_+_54074037	2.498	NM_012242	DKK1	dickkopf 1 homolog (Xenopus laevis)
chrX_-_105282714	1.972	NM_000354	SERPINA7	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr2_+_16080639	1.789	NM_005378	MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr8_-_119964059	1.725	NM_002546	TNFRSF11B	tumor necrosis factor receptor superfamily, member 11b
chr12_+_70759974	1.690	NM_014505	KCNMB4	potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr2_+_16080559	1.527		MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr10_+_115312777	1.427	NM_004132	HABP2	hyaluronan binding protein 2
chr22_+_24105207	1.385	NM_182520	C22orf15	chromosome 22 open reading frame 15
chr8_+_120079423	1.285	NM_006438	COLEC10	collectin sub-family member 10 (C-type lectin)
chr14_-_65409445	1.229	NM_002083	GPX2	glutathione peroxidase 2 (gastrointestinal)
chr3_+_186383770	1.228	NM_000412	HRG	histidine-rich glycoprotein
chr20_-_44006876	1.183	NM_014477	TP53TG5	TP53 target 5
chr17_-_10372875	1.170	NM_017533	MYH4	myosin, heavy chain 4, skeletal muscle
chrX_+_106163605	1.151	NM_020384	CLDN2	claudin 2
chr2_-_231989755	1.137	NM_000867	HTR2B	5-hydroxytryptamine (serotonin) receptor 2B
chr15_-_55880508	1.092		PYGO1	pygopus homolog 1 (Drosophila)
chr16_+_72088507	1.089	NM_001126102 NM_005143	HP	haptoglobin
chr1_-_32801606	1.062	NM_023009	MARCKSL1	MARCKS-like 1
chr6_+_34216344	1.049
chr7_-_27213873	1.042	NM_018951	HOXA10	homeobox A10
chr7_+_94292737	0.997		PEG10	paternally expressed 10
chr16_+_72097124	0.980	NM_020995	HPR	haptoglobin-related protein
chr4_-_109089444	0.946	NM_001130713 NM_001130714 NM_016269	LEF1	lymphoid enhancer-binding factor 1
chr2_-_86564632	0.933	NM_001164731 NM_001164732 NM_022912	REEP1	receptor accessory protein 1
chr10_-_73848766	0.922	NM_001134434 NM_014767	SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr1_-_11107150	0.906		MASP2	mannan-binding lectin serine peptidase 2
chr1_+_153330329	0.879	NM_002965	S100A9	S100 calcium binding protein A9
chr1_+_200993041	0.874
chr7_+_73245192	0.865	NM_001305	CLDN4	claudin 4
chr7_+_94292816	0.849		PEG10	paternally expressed 10
chr9_+_133971902	0.828		AIF1L	allograft inflammatory factor 1-like
chr20_-_43024303	0.814
chr5_+_140480056	0.812	NM_018937	PCDHB3	protocadherin beta 3
chr4_-_100065372	0.801	NM_000670	ADH4	alcohol dehydrogenase 4 (class II), pi polypeptide
chr5_+_140174443	0.796	NM_018905 NM_031495	PCDHA2	protocadherin alpha 2
chr6_-_24645955	0.771	NM_001168375 NM_001168376 NM_001168374 NM_001168377 NM_014809	KIAA0319	KIAA0319
chr1_+_170115187	0.761	NM_001136107	METTL11B	methyltransferase like 11B
chr10_-_91295310	0.751	NM_213606	SLC16A12	solute carrier family 16, member 12 (monocarboxylic acid transporter 12)
chr11_-_75917450	0.740	NM_004626	WNT11	wingless-type MMTV integration site family, member 11
chr6_+_27114860	0.727	NM_080596	HIST1H2AH	histone cluster 1, H2ah
chr10_-_5045967	0.727	NM_001135241	AKR1C2	aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chr1_-_178062734	0.715		LOC100302401	uncharacterized LOC100302401
chr12_-_16759939	0.699	NM_001243613	LMO3	LIM domain only 3 (rhombotin-like 2)
chr13_-_50367027	0.696	NM_002267	KPNA3	karyopherin alpha 3 (importin alpha 4)
chr2_-_241835572	0.683	NM_001085437	C2orf54	chromosome 2 open reading frame 54
chr1_-_53793743	0.683	NM_001018054 NM_004631 NM_017522 NM_033300	LRP8	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr2_+_27070962	0.672	NM_020134 NM_001253723 NM_001253724	DPYSL5	dihydropyrimidinase-like 5
chr11_+_56143099	0.649	NM_001005204 NM_001013356	OR8U1 OR8U8	olfactory receptor, family 8, subfamily U, member 1 olfactory receptor, family 8, subfamily U, member 8
chr1_+_17846818	0.630		ARHGEF10L	Rho guanine nucleotide exchange factor (GEF) 10-like
chr6_+_167536240	0.627	NM_031409	CCR6	chemokine (C-C motif) receptor 6
chr14_-_60097314	0.612		RTN1	reticulon 1
chr6_+_96025343	0.609	NM_024641	MANEA	mannosidase, endo-alpha
chr8_-_17104266	0.603	NM_013354 NM_054026	CNOT7	CCR4-NOT transcription complex, subunit 7
chr18_+_11751470	0.602	NM_001142339 NM_002071	GNAL	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr19_-_6502224	0.601	NM_006087	TUBB4A	tubulin, beta 4A class IVa
chr4_-_103266286	0.601	NM_022154	SLC39A8	solute carrier family 39 (zinc transporter), member 8
chr20_+_36149606	0.599	NM_005386 NM_181689	NNAT	neuronatin
chrX_-_73512376	0.595		FTX	FTX transcript, XIST regulator (non-protein coding)
chr11_+_58874614	0.588	NM_001142703 NM_001142704 NM_198947	FAM111B	family with sequence similarity 111, member B
chr12_+_78225068	0.586	NM_014903	NAV3	neuron navigator 3
chr1_+_9299902	0.581		H6PD	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr1_+_160160284	0.569	NM_001231	CASQ1	calsequestrin 1 (fast-twitch, skeletal muscle)
chr15_+_43809805	0.569	NM_002373	MAP1A	microtubule-associated protein 1A
chr10_-_93669184	0.557	NM_152429	FGFBP3	fibroblast growth factor binding protein 3
chr3_-_123339178	0.547		MYLK	myosin light chain kinase
chr13_-_28543423	0.538		CDX2	caudal type homeobox 2
chr1_-_53793583	0.538		LRP8	low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr3_-_167813058	0.536		GOLIM4	golgi integral membrane protein 4
chr10_-_73848530	0.534	NM_001244950	SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr6_+_15249034	0.534		JARID2	jumonji, AT rich interactive domain 2
chr1_+_100111430	0.533	NM_017734	PALMD	palmdelphin
chr19_-_11450254	0.533	NM_004283	RAB3D	RAB3D, member RAS oncogene family
chr12_+_54426831	0.529	NM_018953	HOXC5	homeobox C5
chr7_+_86974928	0.514	NM_001143935 NM_001243745 NM_021151	CROT	carnitine O-octanoyltransferase
chrX_+_12993224	0.512	NM_021109	TMSB4X	thymosin beta 4, X-linked
chr6_+_131148544	0.508	NM_001195597	LOC100507203	uncharacterized LOC100507203
chr10_-_73848278	0.507		SPOCK2	sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr2_+_179184970	0.505	NM_145739	OSBPL6	oxysterol binding protein-like 6
chr4_-_186877413	0.504		SORBS2	sorbin and SH3 domain containing 2
chr4_-_70626429	0.503	NM_014465	SULT1B1	sulfotransferase family, cytosolic, 1B, member 1
chr15_+_50474357	0.502	NM_001159629 NM_003645	SLC27A2	solute carrier family 27 (fatty acid transporter), member 2
chr6_-_27440459	0.502	NM_007149	ZNF184	zinc finger protein 184
chr11_+_76092336	0.492		LOC100506127	putative uncharacterized protein FLJ37770-like
chr4_-_103265818	0.489		SLC39A8	solute carrier family 39 (zinc transporter), member 8
chr7_-_148725500	0.487		PDIA4	protein disulfide isomerase family A, member 4
chr7_-_148725764	0.479	NM_004911	PDIA4	protein disulfide isomerase family A, member 4
chr1_-_54303933	0.477		TMEM48	transmembrane protein 48
chr3_-_186262114	0.475	NM_017541	CRYGS	crystallin, gamma S
chr10_+_25305507	0.474	NM_024838	THNSL1	threonine synthase-like 1 (S. cerevisiae)
chr11_+_63057371	0.469	NM_001039752	SLC22A10	solute carrier family 22, member 10
chr1_-_20126368	0.466	NM_181719	TMCO4	transmembrane and coiled-coil domains 4
chr3_-_149375584	0.464	NM_001168280 NM_015472	WWTR1	WW domain containing transcription regulator 1
chrX_-_117119282	0.464	NM_001168299	KLHL13	kelch-like 13 (Drosophila)
chr14_-_21493122	0.461	NM_201538 NM_201539 NM_201540 NM_201541	NDRG2	NDRG family member 2
chr5_+_70944968	0.460		MCCC2	methylcrotonoyl-CoA carboxylase 2 (beta)
chr1_+_174844655	0.459	NM_001035230	RABGAP1L	RAB GTPase activating protein 1-like
chr19_+_50084586	0.455	NM_000951	PRRG2	proline rich Gla (G-carboxyglutamic acid) 2
chr3_-_123339423	0.452	NM_053031 NM_053032	MYLK	myosin light chain kinase
chr14_+_85996512	0.445		FLRT2	fibronectin leucine rich transmembrane protein 2
chr2_+_69240137	0.445	NM_018153 NM_032208 NM_053034	ANTXR1	anthrax toxin receptor 1
chr4_+_109543670	0.443		RPL34	ribosomal protein L34
chr3_-_169487602	0.441	NM_032487	ARPM1	actin related protein M1
chr5_+_140734767	0.441	NM_018917 NM_032053	PCDHGA4	protocadherin gamma subfamily A, 4
chr5_+_43602738	0.438	NM_012343	NNT	nicotinamide nucleotide transhydrogenase
chr1_+_168195248	0.437	NM_199344	SFT2D2	SFT2 domain containing 2
chr5_+_43603312	0.435		NNT	nicotinamide nucleotide transhydrogenase
chr1_+_168195257	0.430		SFT2D2	SFT2 domain containing 2
chr18_-_46469118	0.429	NM_001190823	SMAD7	SMAD family member 7
chr1_+_63063186	0.428	NM_014495	ANGPTL3	angiopoietin-like 3
chr8_-_17104103	0.424		CNOT7	CCR4-NOT transcription complex, subunit 7
chr2_+_172378856	0.423	NM_001127383 NM_024843	CYBRD1	cytochrome b reductase 1
chr20_-_44718517	0.423		NCOA5	nuclear receptor coactivator 5
chr11_+_5653484	0.421	NM_130390	TRIM34	tripartite motif containing 34
chr14_-_60097223	0.418		RTN1	reticulon 1
chr1_-_54304107	0.415	NM_001168551 NM_018087	TMEM48	transmembrane protein 48
chrX_-_135962853	0.411
chr7_+_94024201	0.408		COL1A2	collagen, type I, alpha 2
chr17_+_67498391	0.407		MAP2K6	mitogen-activated protein kinase kinase 6
chr4_-_17806820	0.405		DCAF16	DDB1 and CUL4 associated factor 16
chr5_+_140753480	0.405	NM_018919 NM_032086	PCDHGA6	protocadherin gamma subfamily A, 6
chr2_-_9770999	0.405		YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr18_-_25757351	0.404	NM_001792	CDH2	cadherin 2, type 1, N-cadherin (neuronal)
chr19_-_48867149	0.404	NM_018273	TMEM143	transmembrane protein 143
chr18_-_25756946	0.402		CDH2	cadherin 2, type 1, N-cadherin (neuronal)
chr20_-_45976626	0.401		ZMYND8	zinc finger, MYND-type containing 8
chr5_+_140749830	0.400	NM_018924 NM_032097	PCDHGB3	protocadherin gamma subfamily B, 3
chr2_-_211341374	0.396	NM_001136574 NM_006055 NM_001136575	LANCL1	LanC lantibiotic synthetase component C-like 1 (bacterial)
chr18_+_11689135	0.396	NM_182978	GNAL	guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr7_-_91794589	0.395	NM_001161528	LRRD1	leucine-rich repeats and death domain containing 1
chr5_+_43603216	0.393	NM_182977	NNT	nicotinamide nucleotide transhydrogenase
chr3_-_167813175	0.386	NM_014498	GOLIM4	golgi integral membrane protein 4
chr10_+_102123420	0.386
chr3_+_67048726	0.385	NM_032505	KBTBD8	kelch repeat and BTB (POZ) domain containing 8
chr19_-_46220589	0.385
chr1_+_82266081	0.381	NM_012302	LPHN2	latrophilin 2
chr4_+_113152838	0.375	NM_001128426 NM_018569	AP1AR	adaptor-related protein complex 1 associated regulatory protein
chr10_+_71390002	0.374	NM_145306	C10orf35	chromosome 10 open reading frame 35
chr12_-_11139510	0.374	NM_176890	TAS2R50	taste receptor, type 2, member 50
chr1_+_168195241	0.372		SFT2D2	SFT2 domain containing 2
chr20_+_35504514	0.371	NM_080628	C20orf118	chromosome 20 open reading frame 118
chr9_-_34376831	0.370	NM_020702	KIAA1161	KIAA1161
chr4_-_79860369	0.369	NM_001040202	PAQR3	progestin and adipoQ receptor family member III
chr10_-_104211244	0.367	NM_024886	C10orf95	chromosome 10 open reading frame 95
chr7_+_80275967	0.367		CD36	CD36 molecule (thrombospondin receptor)
chr14_-_21572374	0.361
chr3_+_123813527	0.361	NM_001024660 NM_003947	KALRN	kalirin, RhoGEF kinase
chr2_-_9771101	0.359	NM_006826	YWHAQ	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide
chr13_+_39612440	0.358	NM_001012754 NM_001017370	NHLRC3	NHL repeat containing 3
chr1_+_166808680	0.357		POGK	pogo transposable element with KRAB domain
chr10_-_25304865	0.356	NM_145010	ENKUR	enkurin, TRPC channel interacting protein
chr1_+_36348816	0.356		EIF2C1	eukaryotic translation initiation factor 2C, 1
chr4_+_109541721	0.356	NM_000995 NM_033625	RPL34	ribosomal protein L34
chr5_-_135290521	0.355	NM_002302	LECT2	leukocyte cell-derived chemotaxin 2
chr6_+_52529157	0.354		LOC730101	uncharacterized LOC730101
chr6_-_151712644	0.352	NM_020861	ZBTB2	zinc finger and BTB domain containing 2
chrX_-_106960028	0.352		TSC22D3	TSC22 domain family, member 3
chr6_+_159070994	0.352	NM_001009991 NM_001242384 NM_001242394 NM_001242395	SYTL3	synaptotagmin-like 3
chr7_+_128828712	0.352	NM_005631	SMO	smoothened, frizzled family receptor
chr2_+_38155901	0.351	NM_001170792	FAM82A1	family with sequence similarity 82, member A1
chr19_-_52674895	0.350	NM_001102657	ZNF836	zinc finger protein 836
chr20_-_44718564	0.350	NM_020967	NCOA5	nuclear receptor coactivator 5
chr7_+_95115212	0.349	NM_016116 NM_145872	ASB4	ankyrin repeat and SOCS box containing 4
chr20_-_5591487	0.349	NM_019593	GPCPD1	glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr6_-_2840683	0.348		SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr15_+_52043738	0.347	NM_001142885 NM_014548	TMOD2	tropomodulin 2 (neuronal)
chr5_+_43603287	0.347		NNT	nicotinamide nucleotide transhydrogenase
chrX_-_135962872	0.346		RBMX	RNA binding motif protein, X-linked
chr12_-_68726036	0.346	NM_001205028 NM_001205029 NM_017440 NM_020128	MDM1	Mdm1 nuclear protein homolog (mouse)
chr18_+_59992519	0.346	NM_003839	TNFRSF11A	tumor necrosis factor receptor superfamily, member 11a, NFKB activator
chr1_+_36348813	0.345		EIF2C1	eukaryotic translation initiation factor 2C, 1
chr17_-_71088814	0.345		SLC39A11	solute carrier family 39 (metal ion transporter), member 11
chr13_-_72440557	0.345		DACH1	dachshund homolog 1 (Drosophila)
chr15_+_73344824	0.345	NM_001172623 NM_001172624 NM_002499	NEO1	neogenin 1
chr7_+_94023872	0.344	NM_000089	COL1A2	collagen, type I, alpha 2
chr17_-_71088831	0.343		SLC39A11	solute carrier family 39 (metal ion transporter), member 11
chr20_-_656443	0.342
chr5_+_140514787	0.339	NM_015669	PCDHB5	protocadherin beta 5
chr5_+_140235594	0.338	NM_018901 NM_031859 NM_031860	PCDHA10	protocadherin alpha 10
chr17_+_7533452	0.338	NM_001040 NM_001146279 NM_001146280 NM_001146281	SHBG	sex hormone-binding globulin
chr14_+_85996454	0.338	NM_013231	FLRT2	fibronectin leucine rich transmembrane protein 2
chr5_+_133450353	0.337	NM_003202	TCF7	transcription factor 7 (T-cell specific, HMG-box)
chr3_-_112359962	0.336	NM_199511 NM_199512	CCDC80	coiled-coil domain containing 80
chr16_+_2286467	0.336	NM_001374	DNASE1L2	deoxyribonuclease I-like 2
chr16_+_57702156	0.336	NM_170776	GPR97	G protein-coupled receptor 97
chr14_+_105941061	0.335	NM_001312	CRIP2	cysteine-rich protein 2
chr7_-_148725731	0.335		PDIA4	protein disulfide isomerase family A, member 4
chr9_+_97766414	0.334		C9orf3	chromosome 9 open reading frame 3
chr15_+_66995414	0.331		SMAD6	SMAD family member 6
chr17_-_71088832	0.330	NM_001159770 NM_139177	SLC39A11	solute carrier family 39 (metal ion transporter), member 11
chr18_-_65182507	0.330		DSEL	dermatan sulfate epimerase-like
chr15_+_91260575	0.330	NM_000057	BLM	Bloom syndrome, RecQ helicase-like
chr4_-_103266396	0.329	NM_001135147	SLC39A8	solute carrier family 39 (zinc transporter), member 8
chr12_+_56075418	0.328		METTL7B	methyltransferase like 7B
chr14_+_74486049	0.326	NM_025057	C14orf45	chromosome 14 open reading frame 45
chr18_+_21572736	0.324	NM_153211	TTC39C	tetratricopeptide repeat domain 39C
chr10_-_44880452	0.323	NM_000609 NM_001033886 NM_001178134 NM_199168	CXCL12	chemokine (C-X-C motif) ligand 12
chr12_-_81763127	0.323	NM_001220479 NM_001220480	PPFIA2	protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr5_-_114515733	0.320	NM_001017397 NM_001017398 NM_018700	TRIM36	tripartite motif containing 36
chr6_+_167704802	0.320	NM_001143947 NM_018974	UNC93A	unc-93 homolog A (C. elegans)
chr2_-_152146373	0.317	NM_004688	NMI	N-myc (and STAT) interactor

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.