Motif ID: MTF1.p2

Z-value: 0.844


Transcription factors associated with MTF1.p2:

Gene SymbolEntrez IDGene Name
MTF1 4520 metal-regulatory transcription factor 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MTF1hg19_v1_chr1_-_38325224_38325292-0.443.8e-01Click!


Activity profile for motif MTF1.p2.

activity profile for motif MTF1.p2


Sorted Z-values histogram for motif MTF1.p2

Sorted Z-values for motif MTF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MTF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_66045645 0.691 NM_182553
CNIH2
cornichon homolog 2 (Drosophila)
chr14_+_70346113 0.526 NM_001034852
NM_022137
SMOC1

SPARC related modular calcium binding 1

chr7_+_2559396 0.524 NM_001040167
NM_001040168
LFNG

LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

chr12_+_57610577 0.514 NM_007224
NXPH4
neurexophilin 4
chr16_+_56642477 0.497 NM_005953
MT2A
metallothionein 2A
chr9_+_214816 0.467 DOCK8
dedicator of cytokinesis 8
chr2_+_121103670 0.446 NM_002193
INHBB
inhibin, beta B
chr6_+_35227300 0.446 ZNF76
zinc finger protein 76
chr1_+_109642814 0.444 SCARNA2
small Cajal body-specific RNA 2
chr14_+_24439082 0.427 NM_001193636
NM_001193637
NM_001193635
DHRS4L2


DHRS4L1
dehydrogenase/reductase (SDR family) member 4 like 2


dehydrogenase/reductase (SDR family) member 4 like 1
chr2_+_100721380 0.425


chr19_+_30302861 0.418 NM_001238
CCNE1
cyclin E1
chr1_+_33722158 0.403 NM_152493
ZNF362
zinc finger protein 362
chr16_+_56659679 0.393 MT1E
metallothionein 1E
chr19_+_16435632 0.385 NM_016270
KLF2
Kruppel-like factor 2 (lung)
chr4_-_25032306 0.380 NM_018176
LGI2
leucine-rich repeat LGI family, member 2
chr19_-_13030074 0.379 NM_001105578
SYCE2
synaptonemal complex central element protein 2
chr10_+_54074037 0.377 NM_012242
DKK1
dickkopf 1 homolog (Xenopus laevis)
chr9_+_116638544 0.363 NM_133374
ZNF618
zinc finger protein 618
chr3_-_107809754 0.361 NM_001777
NM_198793
CD47

CD47 molecule

chr16_+_56672577 0.357 NM_005946
MT1A
metallothionein 1A
chr12_-_133263988 0.346 POLE
polymerase (DNA directed), epsilon
chr15_+_90777463 0.344 NM_001013657
C15orf58
chromosome 15 open reading frame 58
chr8_+_1712011 0.341 CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chrX_+_117861523 0.340 NM_001560
IL13RA1
interleukin 13 receptor, alpha 1
chr20_-_3218834 0.339 NM_001174090
SLC4A11
solute carrier family 4, sodium borate transporter, member 11
chr6_+_56819923 0.338 BEND6
BEN domain containing 6
chr8_-_119964059 0.334 NM_002546
TNFRSF11B
tumor necrosis factor receptor superfamily, member 11b
chr10_-_44880452 0.332 NM_000609
NM_001033886
NM_001178134
NM_199168
CXCL12



chemokine (C-X-C motif) ligand 12



chr5_-_111093792 0.331 NM_001142477
NM_001142476
C5orf13

chromosome 5 open reading frame 13

chr22_+_51021454 0.324 LOC100144603
uncharacterized transcript
chr15_-_34659245 0.324 NM_153613
LPCAT4
lysophosphatidylcholine acyltransferase 4
chr3_+_186648515 0.322 ST6GAL1
ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr13_-_51417831 0.320 NM_198989
DLEU7
deleted in lymphocytic leukemia, 7
chr15_+_52043738 0.317 NM_001142885
NM_014548
TMOD2

tropomodulin 2 (neuronal)

chr7_-_143105897 0.316 NM_005232
EPHA1
EPH receptor A1
chr14_+_105941061 0.314 NM_001312
CRIP2
cysteine-rich protein 2
chr16_+_56659584 0.313 NM_175617
MT1E
metallothionein 1E
chr5_+_102594406 0.312 NM_033211
C5orf30
chromosome 5 open reading frame 30
chr8_+_1711869 0.312 NM_018941
CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr13_-_101327027 0.299 TMTC4
transmembrane and tetratricopeptide repeat containing 4
chr2_+_231902194 0.298 NM_001144994
C2orf72
chromosome 2 open reading frame 72
chr12_-_54982271 0.290 NM_006741
PPP1R1A
protein phosphatase 1, regulatory (inhibitor) subunit 1A
chr3_-_10749715 0.289 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr16_+_58497548 0.286 NM_020465
NDRG4
NDRG family member 4
chr7_-_150754934 0.286 CDK5
cyclin-dependent kinase 5
chr7_+_30174343 0.286 NM_152793
C7orf41
chromosome 7 open reading frame 41
chr6_+_35182182 0.285 NM_152753
SCUBE3
signal peptide, CUB domain, EGF-like 3
chr22_-_31742217 0.284 NM_014323
NM_032050
NM_032051
NM_032052
PATZ1



POZ (BTB) and AT hook containing zinc finger 1



chr13_+_44947977 0.283 NM_001010897
SERP2
stress-associated endoplasmic reticulum protein family member 2
chr8_+_26371461 0.277 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chr17_-_54991352 0.276 TRIM25
tripartite motif containing 25
chr18_+_11689135 0.276 NM_182978
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr11_+_121322848 0.276 NM_003105
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr16_+_67465019 0.275 NM_000196
HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr5_-_111093251 0.273 NM_001142479
NM_001142480
NM_001142478
C5orf13


chromosome 5 open reading frame 13


chr13_-_101327102 0.270 NM_001079669
NM_032813
TMTC4

transmembrane and tetratricopeptide repeat containing 4

chr6_+_24495166 0.269 NM_001080
NM_170740
ALDH5A1

aldehyde dehydrogenase 5 family, member A1

chr7_+_1126442 0.268 NM_001039966
NM_001505
GPER

G protein-coupled estrogen receptor 1

chr11_+_121323065 0.268 SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chr17_-_1928177 0.265 NM_178568
RTN4RL1
reticulon 4 receptor-like 1
chr20_+_58515408 0.262 NM_001190827
NM_022106
C20orf177

chromosome 20 open reading frame 177

chr2_-_224903933 0.258 NM_001136528
NM_006216
SERPINE2

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2

chr14_+_75894919 0.257 NM_001135048
NM_130469
JDP2

Jun dimerization protein 2

chr8_+_98881277 0.255 NM_002380
NM_030583
MATN2

matrilin 2

chr2_+_112895958 0.255 NM_001128165
NM_153214
FBLN7

fibulin 7

chr13_+_114239047 0.252 NM_007111
TFDP1
transcription factor Dp-1
chr22_+_24891114 0.251 NM_016327
UPB1
ureidopropionase, beta
chr14_+_50087400 0.251 NM_002408
MGAT2
mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr22_-_31742329 0.249 PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr20_-_10654139 0.248 JAG1
jagged 1
chr6_+_27100784 0.246 NM_021064
HIST1H2AG
histone cluster 1, H2ag
chr8_+_146277789 0.246 NM_023080
C8orf33
chromosome 8 open reading frame 33
chr18_-_72921046 0.246 ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr1_-_53793743 0.244 NM_001018054
NM_004631
NM_017522
NM_033300
LRP8



low density lipoprotein receptor-related protein 8, apolipoprotein e receptor



chr1_-_85358851 0.240 NM_012152
LPAR3
lysophosphatidic acid receptor 3
chr8_+_146277830 0.240 C8orf33
chromosome 8 open reading frame 33
chr14_+_96505566 0.238 NM_001252507
C14orf132
chromosome 14 open reading frame 132
chr2_+_119981389 0.236 STEAP3
STEAP family member 3, metalloreductase
chr19_-_11308184 0.236 NM_001136191
KANK2
KN motif and ankyrin repeat domains 2
chr18_-_72920989 0.236


chr15_+_76352323 0.236 C15orf27
chromosome 15 open reading frame 27
chr19_-_36036390 0.235 LOC100506469
uncharacterized LOC100506469
chr16_+_58497993 0.235 NM_001130487
NDRG4
NDRG family member 4
chr3_-_68981674 0.234 NM_001005527
NM_182522
FAM19A4

family with sequence similarity 19 (chemokine (C-C motif)-like), member A4

chr22_+_33197678 0.231 TIMP3
TIMP metallopeptidase inhibitor 3
chr6_+_56819706 0.230 NM_152731
BEND6
BEN domain containing 6
chr11_-_2906960 0.230 NM_000076
NM_001122630
NM_001122631
CDKN1C


cyclin-dependent kinase inhibitor 1C (p57, Kip2)


chr22_+_33197744 0.230 TIMP3
TIMP metallopeptidase inhibitor 3
chr8_+_37594078 0.227 NM_001003791
NM_007175
ERLIN2

ER lipid raft associated 2

chr2_+_208394692 0.227 CREB1
cAMP responsive element binding protein 1
chr15_+_40763159 0.226 NM_130468
CHST14
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr2_+_232573249 0.225 PTMA
prothymosin, alpha
chr7_+_32996961 0.225 NM_007270
FKBP9
FK506 binding protein 9, 63 kDa
chr10_-_135090325 0.225 NM_001109
NM_001164489
NM_001164490
ADAM8


ADAM metallopeptidase domain 8


chr3_+_190231839 0.224 NM_001167928
NM_001167929
NM_001167930
NM_001167931
NM_002182
NM_134470
IL1RAP





interleukin 1 receptor accessory protein





chr8_+_37594171 0.224 ERLIN2
ER lipid raft associated 2
chr12_+_50451486 0.222 NM_001095
NM_020039
ACCN2

amiloride-sensitive cation channel 2, neuronal

chr19_-_2702662 0.222 GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr5_-_159739482 0.222 NM_024565
CCNJL
cyclin J-like
chr6_+_24495016 0.221 ALDH5A1
aldehyde dehydrogenase 5 family, member A1
chr7_+_89840999 0.220 NM_001244944
NM_001244945
NM_152999
NM_001040665
NM_001244946
STEAP2




STEAP family member 2, metalloreductase




chr2_+_119981383 0.219 NM_001008410
NM_018234
NM_182915
STEAP3


STEAP family member 3, metalloreductase


chrX_+_152240726 0.219 NM_001170944
NM_001242319
NM_032882
PNMA6C
PNMA6D
PNMA6A
paraneoplastic antigen like 6C
paraneoplastic antigen like 6D
paraneoplastic antigen like 6A
chr13_-_28543143 0.219 CDX2
caudal type homeobox 2
chr3_-_196439067 0.218 NM_032898
CEP19
centrosomal protein 19kDa
chr12_-_89745997 0.217 DUSP6
dual specificity phosphatase 6
chr4_-_22517339 0.217 NM_145290
GPR125
G protein-coupled receptor 125
chr3_-_64673663 0.216 ADAMTS9
ADAM metallopeptidase with thrombospondin type 1 motif, 9
chr10_+_99473478 0.216 MARVELD1
MARVEL domain containing 1
chrX_-_16888175 0.216 RBBP7
retinoblastoma binding protein 7
chr16_+_56666533 0.213 NM_176870
MT1M
metallothionein 1M
chr11_-_126225445 0.213 FLJ39051
uncharacterized LOC399972
chr12_+_48166929 0.212 NM_017842
SLC48A1
solute carrier family 48 (heme transporter), member 1
chrX_+_152224765 0.211 NM_013364
PNMA3
paraneoplastic antigen MA3
chr2_+_85766291 0.211 MAT2A
methionine adenosyltransferase II, alpha
chr4_+_187065994 0.209 NM_015398
FAM149A
family with sequence similarity 149, member A
chr8_+_74207093 0.208 RDH10
retinol dehydrogenase 10 (all-trans)
chr2_-_20424627 0.207 NM_002997
SDC1
syndecan 1
chr10_+_99473456 0.206 NM_031484
MARVELD1
MARVEL domain containing 1
chr3_+_3841079 0.205 NM_020873
LRRN1
leucine rich repeat neuronal 1
chr14_+_50778981 0.204 NM_001003803
NM_001003805
NM_015684
ATP5S


ATP synthase, H+ transporting, mitochondrial Fo complex, subunit s (factor B)


chr1_-_53793583 0.204 LRP8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr7_+_87563432 0.204 NM_004194
NM_016351
NM_021721
NM_021722
NM_021723
ADAM22




ADAM metallopeptidase domain 22




chr2_+_208394756 0.203 CREB1
cAMP responsive element binding protein 1
chr2_-_56150862 0.202 EFEMP1
EGF containing fibulin-like extracellular matrix protein 1
chr5_-_180288275 0.202 NM_001172638
NM_152283
ZFP62

zinc finger protein 62 homolog (mouse)

chr12_-_21927614 0.201 NM_004982
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr7_-_2883649 0.201 NM_007353
GNA12
guanine nucleotide binding protein (G protein) alpha 12
chr1_+_117452359 0.200 NM_020440
PTGFRN
prostaglandin F2 receptor negative regulator
chr7_-_139477437 0.198 NM_001113239
NM_022740
HIPK2

homeodomain interacting protein kinase 2

chr7_+_5322553 0.198 NM_001040661
NM_153247
SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr11_-_115375065 0.197 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr1_+_38259458 0.196 NM_001031740
NM_001113482
MANEAL

mannosidase, endo-alpha-like

chr10_+_129705359 0.196 PTPRE
protein tyrosine phosphatase, receptor type, E
chr11_+_94822937 0.195 NM_015036
ENDOD1
endonuclease domain containing 1
chr12_+_96588000 0.194 NM_005230
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr16_+_87636492 0.194 NM_020655
JPH3
junctophilin 3
chr6_-_168720389 0.193 NM_214462
DACT2
dapper, antagonist of beta-catenin, homolog 2 (Xenopus laevis)
chrX_+_152224862 0.193 PNMA3
paraneoplastic antigen MA3
chr12_+_53491448 0.193 IGFBP6
insulin-like growth factor binding protein 6
chr18_-_72921280 0.193 NM_175907
ZADH2
zinc binding alcohol dehydrogenase domain containing 2
chr9_-_33167084 0.191 B4GALT1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr16_-_30596808 0.191 NM_152458
ZNF785
zinc finger protein 785
chr1_+_11714861 0.191 NM_001014765
NM_033182
NM_183413
FBXO44


F-box protein 44


chr3_-_14989616 0.189 LOC100505641
uncharacterized LOC100505641
chr16_-_79634610 0.189 NM_001031804
NM_005360
MAF

v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

chr9_-_95896498 0.188 NM_004148
NINJ1
ninjurin 1
chr17_-_11900688 0.188 NM_144680
ZNF18
zinc finger protein 18
chr15_-_51386815 0.188 TNFAIP8L3
tumor necrosis factor, alpha-induced protein 8-like 3
chr15_-_79103571 0.188 NM_014272
ADAMTS7
ADAM metallopeptidase with thrombospondin type 1 motif, 7
chr1_-_17764811 0.188 RCC2
regulator of chromosome condensation 2
chr8_+_26435466 0.187 DPYSL2
dihydropyrimidinase-like 2
chr2_-_20425166 0.187 NM_001006946
SDC1
syndecan 1
chr6_+_14118002 0.186 CD83
CD83 molecule
chr7_+_30324611 0.186 ZNRF2
zinc and ring finger 2
chr12_+_56137063 0.186 NM_005811
GDF11
growth differentiation factor 11
chr13_-_20767100 0.185 NM_004004
GJB2
gap junction protein, beta 2, 26kDa
chr1_+_26438267 0.185 NM_001243533
NM_152835
PDIK1L

PDLIM1 interacting kinase 1 like

chr1_+_179051233 0.185 TOR3A
torsin family 3, member A
chr2_-_109150596 0.184 FLJ38668
uncharacterized LOC644903
chr2_+_131113579 0.184 NM_001142370
NM_014369
PTPN18

protein tyrosine phosphatase, non-receptor type 18 (brain-derived)

chr20_+_3713316 0.184 NM_001197327
NM_052970
HSPA12B

heat shock 70kD protein 12B

chr7_+_30324504 0.184 ZNRF2
zinc and ring finger 2
chr9_-_33167166 0.183 B4GALT1
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr12_+_96588254 0.183 ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr12_+_125478151 0.183 NM_080626
BRI3BP
BRI3 binding protein
chr4_+_154387450 0.182 NM_001131007
NM_015196
KIAA0922

KIAA0922

chr13_+_100633977 0.182 NM_007129
ZIC2
Zic family member 2
chr8_-_63998582 0.181 NM_000370
TTPA
tocopherol (alpha) transfer protein
chr11_+_64001974 0.181 NM_001243733
NM_003377
VEGFB

vascular endothelial growth factor B

chr1_+_23037329 0.180 NM_004442
NM_017449
EPHB2

EPH receptor B2

chr2_+_24272583 0.178 NM_004116
NM_054033
FKBP1B

FK506 binding protein 1B, 12.6 kDa

chr6_-_52441815 0.177 NM_012288
TRAM2
translocation associated membrane protein 2
chr6_-_52441714 0.177 TRAM2
translocation associated membrane protein 2
chr11_+_111169965 0.175 NM_001136105
C11orf93
chromosome 11 open reading frame 93
chr2_-_165698318 0.175 COBLL1
COBL-like 1
chr6_+_52529157 0.175 LOC730101
uncharacterized LOC730101
chr11_-_67397383 0.175 NM_001243750
NM_181843
NUDT8

nudix (nucleoside diphosphate linked moiety X)-type motif 8

chr1_-_178062734 0.174 LOC100302401
uncharacterized LOC100302401
chr7_+_142985462 0.174 CASP2
caspase 2, apoptosis-related cysteine peptidase
chr1_-_23670743 0.174 NM_001102397
NM_001102398
NM_001102399
NM_005826
HNRNPR



heterogeneous nuclear ribonucleoprotein R



chr9_+_133971902 0.173 AIF1L
allograft inflammatory factor 1-like
chr20_-_58515258 0.173 NM_006242
PPP1R3D
protein phosphatase 1, regulatory subunit 3D
chr11_-_66084501 0.172 NM_020404
CD248
CD248 molecule, endosialin
chr2_+_207308280 0.171 NM_003812
ADAM23
ADAM metallopeptidase domain 23
chr20_-_5107185 0.171 NM_002592
PCNA
proliferating cell nuclear antigen
chr1_+_90287543 0.171 LRRC8D
leucine rich repeat containing 8 family, member D
chr1_+_184356186 0.170 C1orf21
chromosome 1 open reading frame 21
chr1_+_184356227 0.170 C1orf21
chromosome 1 open reading frame 21
chr13_+_27844936 0.169 RASL11A
RAS-like, family 11, member A
chr1_-_184723952 0.169 EDEM3
ER degradation enhancer, mannosidase alpha-like 3
chr3_+_58223228 0.169 NM_020676
ABHD6
abhydrolase domain containing 6
chr1_+_28199053 0.169 NM_001039477
NM_001105556
NM_004848
C1orf38


chromosome 1 open reading frame 38


chr11_+_13030879 0.168 NM_001080521
RASSF10
Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
chrX_-_16888442 0.168 RBBP7
retinoblastoma binding protein 7
chr3_-_52090090 0.168 NM_001947
DUSP7
dual specificity phosphatase 7
chrX_+_9432980 0.168 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr8_+_26435339 0.168 NM_001386
DPYSL2
dihydropyrimidinase-like 2
chr15_+_90895476 0.167 NM_001004309
ZNF774
zinc finger protein 774

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.