Motif ID: MYFfamily.p2

Z-value: 2.152


Transcription factors associated with MYFfamily.p2:

Gene SymbolEntrez IDGene Name
MYF5 4617 myogenic factor 5
MYF6 4618 myogenic factor 6 (herculin)
MYOD1 4654 myogenic differentiation 1
MYOG 4656 myogenin (myogenic factor 4)



Activity profile for motif MYFfamily.p2.

activity profile for motif MYFfamily.p2


Sorted Z-values histogram for motif MYFfamily.p2

Sorted Z-values for motif MYFfamily.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYFfamily.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_99282597 2.442 POU3F2
POU class 3 homeobox 2
chr10_-_21805715 2.308 C10orf140
chromosome 10 open reading frame 140
chr5_-_147162056 2.302 JAKMIP2
janus kinase and microtubule interacting protein 2
chr5_+_137774632 2.059 NM_016606
REEP2
receptor accessory protein 2
chr7_-_84816170 2.054 SEMA3D
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D
chr12_-_89745753 1.979 DUSP6
dual specificity phosphatase 6
chr1_-_53793743 1.934 NM_001018054
NM_004631
NM_017522
NM_033300
LRP8



low density lipoprotein receptor-related protein 8, apolipoprotein e receptor



chr7_+_96635289 1.919 NM_005222
DLX6
distal-less homeobox 6
chr5_-_147162251 1.809 NM_014790
JAKMIP2
janus kinase and microtubule interacting protein 2
chr15_+_41221530 1.771 NM_019074
DLL4
delta-like 4 (Drosophila)
chr19_-_18314731 1.755 NM_002866
RAB3A
RAB3A, member RAS oncogene family
chr3_+_3841079 1.744 NM_020873
LRRN1
leucine rich repeat neuronal 1
chr1_+_90286595 1.738 LRRC8D
leucine rich repeat containing 8 family, member D
chr1_-_72748491 1.702


chr12_-_89745997 1.691 DUSP6
dual specificity phosphatase 6
chr12_+_125478234 1.651 BRI3BP
BRI3 binding protein
chr7_-_27239724 1.641 NM_000522
HOXA13
homeobox A13
chr11_-_86666089 1.628 FZD4
frizzled family receptor 4
chr14_+_70346113 1.604 NM_001034852
NM_022137
SMOC1

SPARC related modular calcium binding 1

chr14_+_90863302 1.599 NM_006888
CALM1
calmodulin 1 (phosphorylase kinase, delta)
chr22_-_30783301 1.590 NM_001017981
RNF215
ring finger protein 215
chr10_-_30316338 1.561 KIAA1462
KIAA1462
chr11_-_86666211 1.529 NM_012193
FZD4
frizzled family receptor 4
chr11_-_66115016 1.519 NM_006876
B3GNT1
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
chr4_-_25032306 1.509 NM_018176
LGI2
leucine-rich repeat LGI family, member 2
chr3_+_159943252 1.463 NM_001168214
C3orf80
chromosome 3 open reading frame 80
chr1_+_87797301 1.460


chr2_+_158114109 1.451 NM_014568
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr1_+_154966061 1.428 NM_018655
LENEP
lens epithelial protein
chr3_-_107809754 1.407 NM_001777
NM_198793
CD47

CD47 molecule

chr3_+_159943628 1.382 C3orf80
chromosome 3 open reading frame 80
chr1_-_72748147 1.376 NM_173808
NEGR1
neuronal growth regulator 1
chr10_+_54074037 1.364 NM_012242
DKK1
dickkopf 1 homolog (Xenopus laevis)
chr17_+_40913211 1.354 NM_005854
RAMP2
receptor (G protein-coupled) activity modifying protein 2
chr15_+_96873845 1.354 NM_021005
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr12_+_125478151 1.296 NM_080626
BRI3BP
BRI3 binding protein
chr5_-_147162175 1.287 JAKMIP2
janus kinase and microtubule interacting protein 2
chr20_-_48184652 1.278 NM_000961
PTGIS
prostaglandin I2 (prostacyclin) synthase
chr1_-_231114596 1.273 TTC13
tetratricopeptide repeat domain 13
chr5_-_147162264 1.262 JAKMIP2
janus kinase and microtubule interacting protein 2
chr17_+_14204326 1.246 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr15_-_34659245 1.235 NM_153613
LPCAT4
lysophosphatidylcholine acyltransferase 4
chr22_+_33197678 1.234 TIMP3
TIMP metallopeptidase inhibitor 3
chr7_+_72569025 1.230 GTF2IP1
general transcription factor IIi, pseudogene 1
chr7_+_2559396 1.230 NM_001040167
NM_001040168
LFNG

LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase

chr16_+_67876381 1.226 THAP11
THAP domain containing 11
chr12_+_66218879 1.220 HMGA2
high mobility group AT-hook 2
chr5_-_146258143 1.217 NM_004576
NM_181675
NM_001127381
PPP2R2B


protein phosphatase 2, regulatory subunit B, beta


chr2_-_160654668 1.195 CD302
CD302 molecule
chr13_-_72440143 1.177 DACH1
dachshund homolog 1 (Drosophila)
chr20_+_58515408 1.169 NM_001190827
NM_022106
C20orf177

chromosome 20 open reading frame 177

chr1_-_53793583 1.156 LRP8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr6_-_27775683 1.155 NM_003519
HIST1H2BL
histone cluster 1, H2bl
chrX_+_21392396 1.149 NM_001168647
NM_001168648
NM_001168649
NM_014927
CNKSR2



connector enhancer of kinase suppressor of Ras 2



chr1_-_231114606 1.145 TTC13
tetratricopeptide repeat domain 13
chr1_+_90286469 1.130 NM_001134479
LRRC8D
leucine rich repeat containing 8 family, member D
chr1_+_1361507 1.126 NM_001146685
TMEM88B
transmembrane protein 88B
chr6_+_107811272 1.121 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr1_-_231114617 1.114 NM_001122835
NM_024525
TTC13

tetratricopeptide repeat domain 13

chr6_+_32122194 1.113 PPT2
palmitoyl-protein thioesterase 2
chr20_-_44563684 1.091 FLJ40606
uncharacterized LOC643549
chr16_+_4430878 1.087 VASN
vasorin
chr3_-_167813058 1.085 GOLIM4
golgi integral membrane protein 4
chr13_-_72440557 1.082 DACH1
dachshund homolog 1 (Drosophila)
chr10_-_73848530 1.052 NM_001244950
SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr22_+_48027451 1.046 LOC284930
uncharacterized LOC284930
chr15_+_43809805 1.041 NM_002373
MAP1A
microtubule-associated protein 1A
chr12_+_66218568 1.035 HMGA2
high mobility group AT-hook 2
chr16_+_67233013 1.028 NM_024712
ELMO3
engulfment and cell motility 3
chr16_+_67465019 1.013 NM_000196
HSD11B2
hydroxysteroid (11-beta) dehydrogenase 2
chr17_+_42634598 1.009 NM_001466
FZD2
frizzled family receptor 2
chr10_+_72163914 1.007 EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr7_+_90893735 1.006 NM_003505
FZD1
frizzled family receptor 1
chr5_+_126626455 1.006 NM_032446
MEGF10
multiple EGF-like-domains 10
chr1_-_102462371 1.005 OLFM3
olfactomedin 3
chr10_+_111765725 0.995 NM_019903
ADD3
adducin 3 (gamma)
chrX_-_118827155 0.993 SEPT6
septin 6
chr10_+_115803805 0.988 NM_000684
ADRB1
adrenergic, beta-1-, receptor
chr4_+_113970784 0.973 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chrX_-_118827060 0.972 SEPT6
septin 6
chr20_-_35374530 0.971 NM_022477
NM_032013
NDRG3

NDRG family member 3

chr20_+_44520203 0.969 CTSA
cathepsin A
chr14_-_60337350 0.967 NM_021136
RTN1
reticulon 1
chr5_+_128796005 0.956 NM_133638
ADAMTS19
ADAM metallopeptidase with thrombospondin type 1 motif, 19
chr2_-_160654736 0.955 NM_001198763
NM_001198764
NM_014880
CD302


CD302 molecule


chr14_+_29236882 0.944 FOXG1
forkhead box G1
chrX_-_140271205 0.939 LDOC1
leucine zipper, down-regulated in cancer 1
chr20_+_44519924 0.933 CTSA
cathepsin A
chr10_+_72163899 0.931 EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr3_+_110790460 0.925 NM_001243286
NM_015480
PVRL3

poliovirus receptor-related 3

chr2_-_152684963 0.923 NM_001037174
NM_012097
NM_177985
ARL5A


ADP-ribosylation factor-like 5A


chr17_-_42296923 0.918 UBTF
upstream binding transcription factor, RNA polymerase I
chr5_+_170846659 0.918 NM_003862
FGF18
fibroblast growth factor 18
chr1_+_231114839 0.918


chr4_+_154387450 0.912 NM_001131007
NM_015196
KIAA0922

KIAA0922

chr17_+_40913233 0.902 RAMP2
receptor (G protein-coupled) activity modifying protein 2
chr8_+_92082423 0.901 NM_016023
OTUD6B
OTU domain containing 6B
chr9_+_114393543 0.900 NM_001015882
NM_004125
DNAJC25
DNAJC25-GNG10
DnaJ (Hsp40) homolog, subfamily C , member 25
DNAJC25-GNG10 readthrough
chr1_-_32707198 0.899 MTMR9LP
myotubularin related protein 9-like, pseudogene
chr12_+_56137063 0.899 NM_005811
GDF11
growth differentiation factor 11
chrX_-_20284708 0.898 NM_004586
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr15_-_56035176 0.889 NM_173814
PRTG
protogenin
chr1_-_32403975 0.889 NM_080391
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr20_-_31071187 0.886 NM_080616
C20orf112
chromosome 20 open reading frame 112
chr9_-_128003615 0.885 HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chrX_-_119694492 0.884 CUL4B
cullin 4B
chr8_-_62627111 0.884 ASPH
aspartate beta-hydroxylase
chr2_+_203499819 0.880 NM_173511
FAM117B
family with sequence similarity 117, member B
chr16_-_19533285 0.878 NM_016641
GDE1
glycerophosphodiester phosphodiesterase 1
chrX_-_100603673 0.874 NM_001145951
TIMM8A
translocase of inner mitochondrial membrane 8 homolog A (yeast)
chr3_-_124774735 0.873 NM_020733
HEG1
HEG homolog 1 (zebrafish)
chr10_-_73848309 0.869 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr15_-_53082087 0.867 NM_004498
ONECUT1
one cut homeobox 1
chr5_-_112824526 0.861 NM_001085377
MCC
mutated in colorectal cancers
chr15_-_93198602 0.859 NM_207446
FAM174B
family with sequence similarity 174, member B
chr20_-_35374468 0.853 NDRG3
NDRG family member 3
chr10_-_73848263 0.853 SPOCK2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 2
chr10_+_72163860 0.853 NM_004096
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr1_-_33338081 0.847 NM_001171941
FNDC5
fibronectin type III domain containing 5
chr9_-_128003348 0.844 HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chrX_-_118827116 0.843 SEPT6
septin 6
chr5_+_42423811 0.835 NM_000163
GHR
growth hormone receptor
chr4_-_155412411 0.832 DCHS2
dachsous 2 (Drosophila)
chr5_+_137774897 0.830 REEP2
receptor accessory protein 2
chr22_+_33197744 0.829 TIMP3
TIMP metallopeptidase inhibitor 3
chr15_+_79603544 0.828 TMED3
transmembrane emp24 protein transport domain containing 3
chr13_-_37494370 0.827 NM_001127217
NM_005905
SMAD9

SMAD family member 9

chr6_-_150185161 0.827 LRP11
low density lipoprotein receptor-related protein 11
chr5_-_72743829 0.824 FOXD1
forkhead box D1
chr22_+_24115035 0.816 NM_005940
MMP11
matrix metallopeptidase 11 (stromelysin 3)
chr2_-_190445466 0.814 SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chrX_-_50213589 0.810 NM_001013742
DGKK
diacylglycerol kinase, kappa
chr3_-_169381417 0.809 NM_001205194
NM_004991
MECOM

MDS1 and EVI1 complex locus

chr3_-_10547221 0.805 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr2_+_112895958 0.803 NM_001128165
NM_153214
FBLN7

fibulin 7

chr12_-_63544615 0.799 AVPR1A
arginine vasopressin receptor 1A
chrX_-_54209639 0.793 NM_017848
NM_198456
FAM120C

family with sequence similarity 120C

chr3_+_32148000 0.792 NM_015141
GPD1L
glycerol-3-phosphate dehydrogenase 1-like
chr1_+_54519259 0.789 NM_153035
TCEANC2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr1_-_6295989 0.789 ICMT
isoprenylcysteine carboxyl methyltransferase
chr4_-_25864430 0.781 NM_015187
SEL1L3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr1_-_231114580 0.774 TTC13
tetratricopeptide repeat domain 13
chr17_+_28705960 0.773 CPD
carboxypeptidase D
chr7_-_92855780 0.772 NM_001039372
HEPACAM2
HEPACAM family member 2
chr8_-_62626929 0.772 ASPH
aspartate beta-hydroxylase
chr21_+_40823779 0.770 NM_007341
SH3BGR
SH3 domain binding glutamic acid-rich protein
chr12_+_74933559 0.770


chr3_-_10547267 0.767 NM_001001331
NM_001683
ATP2B2

ATPase, Ca++ transporting, plasma membrane 2

chr20_+_44520021 0.766 CTSA
cathepsin A
chr1_+_25071906 0.765 CLIC4
chloride intracellular channel 4
chr5_+_170847059 0.764 FGF18
fibroblast growth factor 18
chr4_+_159091903 0.761 LOC285505
uncharacterized LOC285505
chr6_+_27100784 0.756 NM_021064
HIST1H2AG
histone cluster 1, H2ag
chr20_-_44519629 0.755 NM_080749
NEURL2
neuralized homolog 2 (Drosophila)
chr12_+_70759974 0.754 NM_014505
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr1_-_17764989 0.752 RCC2
regulator of chromosome condensation 2
chrX_-_140271293 0.751 NM_012317
LDOC1
leucine zipper, down-regulated in cancer 1
chr2_+_121103670 0.748 NM_002193
INHBB
inhibin, beta B
chr1_-_6295967 0.746 ICMT
isoprenylcysteine carboxyl methyltransferase
chr8_-_91657739 0.746 TMEM64
transmembrane protein 64
chr18_+_72998258 0.745 TSHZ1
teashirt zinc finger homeobox 1
chr8_-_33457435 0.744 NM_024025
DUSP26
dual specificity phosphatase 26 (putative)
chr1_+_51434375 0.744 CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr1_-_154531083 0.743 NM_017582
UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr6_+_114178516 0.742 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr8_-_103136486 0.740 NM_001040624
NM_001040625
NM_001040626
NM_001040627
NM_001040628
NM_001040629
NCALD





neurocalcin delta





chr19_-_40023449 0.738 NM_152361
EID2B
EP300 interacting inhibitor of differentiation 2B
chr2_-_190445612 0.736 SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr3_-_10547340 0.736 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr2_-_241831385 0.734 NM_024861
C2orf54
chromosome 2 open reading frame 54
chr9_+_78505514 0.731 NM_001190482
NM_006200
PCSK5

proprotein convertase subtilisin/kexin type 5

chr2_+_111878450 0.727 NM_001204106
NM_001204107
NM_001204108
NM_001204109
NM_001204110
NM_001204111
NM_001204112
NM_001204113
NM_006538
NM_138621
NM_138622
NM_138623
NM_138624
NM_138625
NM_138626
NM_138627
NM_207002
NM_207003
BCL2L11

















BCL2-like 11 (apoptosis facilitator)

















chr2_-_99347430 0.726 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr17_+_67410825 0.725 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr3_-_12200339 0.724 TIMP4
TIMP metallopeptidase inhibitor 4
chr17_-_42297037 0.723 NM_001076684
NM_014233
UBTF

upstream binding transcription factor, RNA polymerase I

chr19_+_18284631 0.723 IFI30
interferon, gamma-inducible protein 30
chr16_-_47177902 0.722 NM_001201477
NM_018092
NETO2

neuropilin (NRP) and tolloid (TLL)-like 2

chr9_-_128003634 0.721 NM_005347
HSPA5
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)
chr8_+_74206772 0.719 NM_172037
RDH10
retinol dehydrogenase 10 (all-trans)
chr17_-_59668540 0.714 NM_199290
NACA2
nascent polypeptide-associated complex alpha subunit 2
chr16_+_87636492 0.714 NM_020655
JPH3
junctophilin 3
chr1_+_51434231 0.713 NM_001262
CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr11_-_67397383 0.709 NM_001243750
NM_181843
NUDT8

nudix (nucleoside diphosphate linked moiety X)-type motif 8

chrY_-_21154560 0.709 NM_013230
CD24
CD24P4
CD24 molecule
CD24 molecule pseudogene 4
chr1_+_51434447 0.707 CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr1_-_57285368 0.706 NM_001004303
C1orf168
chromosome 1 open reading frame 168
chr6_+_27861202 0.702 NM_003527
HIST1H2BO
histone cluster 1, H2bo
chr3_-_120068077 0.701 NM_001099678
LRRC58
leucine rich repeat containing 58
chr1_-_32403888 0.698 PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr3_+_110790774 0.697 NM_001243288
PVRL3
poliovirus receptor-related 3
chr1_+_179051233 0.692 TOR3A
torsin family 3, member A
chr6_+_14118002 0.690 CD83
CD83 molecule
chr16_-_47177832 0.689 NETO2
neuropilin (NRP) and tolloid (TLL)-like 2
chr9_+_127539382 0.687 NM_182487
OLFML2A
olfactomedin-like 2A
chr9_+_108006892 0.681 NM_080546
SLC44A1
solute carrier family 44, member 1
chr5_+_176560882 0.681 NSD1
nuclear receptor binding SET domain protein 1
chr2_+_173292344 0.680 ITGA6
integrin, alpha 6
chr3_+_49507470 0.679 NM_001165928
NM_001177634
NM_001177635
NM_001177636
NM_001177637
NM_001177638
NM_001177639
NM_001177640
NM_001177641
NM_001177642
NM_001177644
NM_004393
DAG1











dystroglycan 1 (dystrophin-associated glycoprotein 1)











chr9_+_77112251 0.678 NM_006914
RORB
RAR-related orphan receptor B

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
212.43 1.13e-02 GO:0060839 endothelial cell fate commitment
212.43 1.13e-02 GO:0072148 epithelial cell fate commitment
13.75 1.16e-02 GO:0033273 response to vitamin
3.35 1.56e-02 GO:0009653 anatomical structure morphogenesis
39.85 2.17e-02 GO:0007223 Wnt receptor signaling pathway, calcium modulating pathway
6.70 2.89e-02 GO:0007420 brain development
5.55 3.19e-02 GO:0007417 central nervous system development

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
63.74 5.86e-04 GO:0042813 Wnt receptor activity
45.54 1.69e-03 GO:0017147 Wnt-protein binding