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• Activity deltas table
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Motif ID: NFKB1_REL_RELA.p2

Z-value: 4.359

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr10_+_104154228	9.220	NM_001077493 NM_001077494	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr10_+_104155431	7.193	NM_002502	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr4_-_74964836	6.356		CXCL2	chemokine (C-X-C motif) ligand 2
chr7_+_18548899	6.328	NM_001204147 NM_001204148	HDAC9	histone deacetylase 9
chr19_+_45504686	5.694	NM_006509	RELB	v-rel reticuloendotheliosis viral oncogene homolog B
chr16_-_66959418	5.495	NM_001128850 NM_004165	RRAD	Ras-related associated with diabetes
chr9_+_35560424	5.383		RUSC2	RUN and SH3 domain containing 2
chr4_+_74735107	5.225	NM_001511	CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr7_+_1570321	5.058	NM_002360	MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr8_-_103667882	4.995	NM_005655	KLF10	Kruppel-like factor 10
chr7_+_18548963	4.907		HDAC9	histone deacetylase 9
chr12_-_76425375	4.646	NM_007350	PHLDA1	pleckstrin homology-like domain, family A, member 1
chr4_-_74864296	4.593	NM_002994	CXCL5	chemokine (C-X-C motif) ligand 5
chr19_+_45971249	4.437	NM_001114171 NM_006732	FOSB	FBJ murine osteosarcoma viral oncogene homolog B
chr12_-_76425207	4.381		PHLDA1	pleckstrin homology-like domain, family A, member 1
chr12_+_52445185	4.344	NM_002135 NM_173157	NR4A1	nuclear receptor subfamily 4, group A, member 1
chr8_-_95274540	4.302	NM_005261 NM_181702	GEM	GTP binding protein overexpressed in skeletal muscle
chr4_-_74964996	4.264	NM_002089	CXCL2	chemokine (C-X-C motif) ligand 2
chr11_+_122526339	4.090	NM_032873	UBASH3B	ubiquitin associated and SH3 domain containing B
chr11_+_102188180	4.042	NM_001165 NM_182962	BIRC3	baculoviral IAP repeat containing 3
chr4_+_74702272	3.877	NM_002993	CXCL6	chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)
chr19_-_4338750	3.836	NM_001013841 NM_017720	STAP2	signal transducing adaptor family member 2
chr19_-_47734215	3.741	NM_014417	BBC3	BCL2 binding component 3
chr17_+_7461591	3.733	NM_001198622 NM_001198623 NM_001198624 NM_003808 NM_172087 NM_172088	TNFSF13	tumor necrosis factor (ligand) superfamily, member 13
chr8_-_95274520	3.714		GEM	GTP binding protein overexpressed in skeletal muscle
chr1_+_201979689	3.700	NM_001114309 NM_004433	ELF3	E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr16_+_3115639	3.661		IL32	interleukin 32
chr1_+_201979747	3.616		ELF3	E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr4_-_74904329	3.611	NM_002090	CXCL3	chemokine (C-X-C motif) ligand 3
chr16_+_3115312	3.495	NM_001012631 NM_001012633 NM_001012718 NM_004221	IL32	interleukin 32
chr19_+_2476122	3.459	NM_015675	GADD45B	growth arrest and DNA-damage-inducible, beta
chr10_-_73533196	3.405	NM_022153	C10orf54	chromosome 10 open reading frame 54
chr1_+_45274153	3.378	NM_001136537	BTBD19	BTB (POZ) domain containing 19
chr10_-_3827205	3.365		KLF6	Kruppel-like factor 6
chr12_+_120740123	3.215	NM_012240	SIRT4	sirtuin 4
chr1_+_35331533	3.206
chr19_+_40697516	3.200	NM_002446	MAP3K10	mitogen-activated protein kinase kinase kinase 10
chr1_+_110453232	3.191	NM_000757 NM_172210 NM_172212	CSF1	colony stimulating factor 1 (macrophage)
chr1_-_59248287	3.185		JUN	jun proto-oncogene
chr1_+_110453456	3.143		CSF1	colony stimulating factor 1 (macrophage)
chr1_+_170633312	3.143	NM_006902 NM_022716	PRRX1	paired related homeobox 1
chr16_+_50775960	3.106	NM_001042355 NM_015247	CYLD	cylindromatosis (turban tumor syndrome)
chr16_-_2059759	3.077	NM_178167	ZNF598	zinc finger protein 598
chr19_-_48614013	3.022	NM_001159322 NM_001159323 NM_003706	PLA2G4C	phospholipase A2, group IVC (cytosolic, calcium-independent)
chr1_+_45266035	2.995	NM_004073	PLK3	polo-like kinase 3
chr3_-_42814734	2.955	NM_144719	CCDC13	coiled-coil domain containing 13
chr1_+_45266048	2.878		PLK3	polo-like kinase 3
chr2_+_28615668	2.838		FOSL2	FOS-like antigen 2
chr6_-_29527701	2.818	NM_006398	UBD	ubiquitin D
chr4_+_103422730	2.811		NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr16_+_3115611	2.803	NM_001012635	IL32	interleukin 32
chr6_-_29527477	2.783		UBD	ubiquitin D
chr15_+_85923739	2.779	NM_006738 NM_007200	AKAP13	A kinase (PRKA) anchor protein 13
chr16_-_122573	2.769	NM_022450	RHBDF1	rhomboid 5 homolog 1 (Drosophila)
chr1_+_37940180	2.767		ZC3H12A	zinc finger CCCH-type containing 12A
chr19_+_39390618	2.749		NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr3_+_157154579	2.741	NM_002852	PTX3	pentraxin 3, long
chr7_-_100061893	2.739	NM_001004323	C7orf61	chromosome 7 open reading frame 61
chr8_-_11324184	2.728	NM_053279	FAM167A	family with sequence similarity 167, member A
chr16_+_3115638	2.725	NM_001012634	IL32	interleukin 32
chr19_+_39390570	2.692		NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr6_+_29974352	2.669		HLA-J	major histocompatibility complex, class I, J (pseudogene)
chr10_+_13142055	2.655	NM_001008211 NM_001008212 NM_001008213 NM_021980	OPTN	optineurin
chr11_+_46299554	2.650		CREB3L1	cAMP responsive element binding protein 3-like 1
chr19_+_39390258	2.643	NM_001243116	NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr16_+_50776012	2.608	NM_001042412	CYLD	cylindromatosis (turban tumor syndrome)
chr4_+_103422822	2.604		NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr1_-_1475739	2.545	NM_001114748	TMEM240	transmembrane protein 240
chr2_-_74669005	2.544		RTKN	rhotekin
chr3_-_39195101	2.524	NM_033027	CSRNP1	cysteine-serine-rich nuclear protein 1
chr19_-_46283281	2.482
chr7_+_149412027	2.468	NM_032534	KRBA1	KRAB-A domain containing 1
chr9_-_110250707	2.455		KLF4	Kruppel-like factor 4 (gut)
chr4_+_103422479	2.450	NM_001165412 NM_003998	NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr19_+_55795533	2.424	NM_032430	BRSK1	BR serine/threonine kinase 1
chr19_-_46295647	2.412		DMWD	dystrophia myotonica, WD repeat containing
chr20_-_44600787	2.404	NM_022095	ZNF335	zinc finger protein 335
chr5_+_177540465	2.400	NM_015111	N4BP3	NEDD4 binding protein 3
chr14_-_35873823	2.395	NM_020529	NFKBIA	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
chr4_+_103422553	2.386		NFKB1	nuclear factor of kappa light polypeptide gene enhancer in B-cells 1
chr1_+_212788359	2.358	NM_001206486	ATF3	activating transcription factor 3
chr20_-_44600939	2.345		ZNF335	zinc finger protein 335
chr17_-_39092714	2.334		KRT23	keratin 23 (histone deacetylase inducible)
chr15_-_40398286	2.326	NM_001003942 NM_001003943	BMF	Bcl2 modifying factor
chr1_-_89641722	2.324	NM_207398	GBP7	guanylate binding protein 7
chr1_+_203274646	2.314	NM_006763	BTG2	BTG family, member 2
chr6_-_31324955	2.306		HLA-B	major histocompatibility complex, class I, B
chr19_+_13205956	2.292		NFIX	nuclear factor I/X (CCAAT-binding transcription factor)
chr3_-_39195034	2.292		CSRNP1	cysteine-serine-rich nuclear protein 1
chr17_+_16318848	2.285	NM_016113	TRPV2	transient receptor potential cation channel, subfamily V, member 2
chr12_+_93964801	2.276		SOCS2	suppressor of cytokine signaling 2
chr19_+_55795766	2.268		BRSK1	BR serine/threonine kinase 1
chr5_-_150466696	2.204	NM_001252391 NM_001252392	TNIP1	TNFAIP3 interacting protein 1
chr2_+_228678556	2.150	NM_001130046 NM_004591	CCL20	chemokine (C-C motif) ligand 20
chr7_+_17338182	2.100	NM_001621	AHR	aryl hydrocarbon receptor
chr3_-_156878481	2.089	NM_020307	CCNL1	cyclin L1
chr19_-_4831711	2.071	NM_182919	TICAM1	toll-like receptor adaptor molecule 1
chr14_+_75988765	2.063	NM_006399	BATF	basic leucine zipper transcription factor, ATF-like
chr12_-_58160823	2.027	NM_000785	CYP27B1	cytochrome P450, family 27, subfamily B, polypeptide 1
chr11_+_65984213	2.026		PACS1	phosphofurin acidic cluster sorting protein 1
chr8_+_128806720	2.022		PVT1	Pvt1 oncogene (non-protein coding)
chr17_+_38474513	2.015		RARA	retinoic acid receptor, alpha
chr5_+_176875325	2.014	NM_001174102	PRR7	proline rich 7 (synaptic)
chr11_+_46299161	2.013	NM_052854	CREB3L1	cAMP responsive element binding protein 3-like 1
chr10_-_125851850	2.010	NM_014863 NM_015892	CHST15	carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr19_+_827821	1.999	NM_001700	AZU1	azurocidin 1
chr22_-_38506532	1.984		BAIAP2L2	BAI1-associated protein 2-like 2
chr7_+_150745604	1.975	NM_004769 NM_020321 NM_020322	ACCN3	amiloride-sensitive cation channel 3
chr22_+_38599026	1.959	NM_001161573	MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr2_-_74669026	1.952		RTKN	rhotekin
chr17_+_16318911	1.939		TRPV2	transient receptor potential cation channel, subfamily V, member 2
chr18_+_23806385	1.937	NM_005640	TAF4B	TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
chr7_-_104654049	1.924		LOC100216545	uncharacterized LOC100216545
chr17_+_38474544	1.923		RARA	retinoic acid receptor, alpha
chr5_+_60628085	1.915	NM_020928	ZSWIM6	zinc finger, SWIM-type containing 6
chr19_+_48673936	1.906		C19orf68	chromosome 19 open reading frame 68
chr5_+_172571444	1.896	NM_001205 NM_013978 NM_013979 NM_013980	BNIP1	BCL2/adenovirus E1B 19kDa interacting protein 1
chr17_+_38474472	1.891	NM_001145301 NM_001145302	RARA	retinoic acid receptor, alpha
chr6_+_17281773	1.890	NM_001143942	RBM24	RNA binding motif protein 24
chr6_+_31540092	1.882	NM_000595	LTA	lymphotoxin alpha (TNF superfamily, member 1)
chr17_+_45973515	1.874	NM_003110	SP2	Sp2 transcription factor
chr6_+_29910246	1.872	NM_001242758 NM_002116	HLA-A	major histocompatibility complex, class I, A
chr1_-_156675237	1.871	NM_001878 NM_001199723	CRABP2	cellular retinoic acid binding protein 2
chr11_+_59522905	1.868		STX3	syntaxin 3
chr6_+_108882068	1.838	NM_001455	FOXO3	forkhead box O3
chr1_+_162039469	1.836	NM_001164757 NM_014697	NOS1AP	nitric oxide synthase 1 (neuronal) adaptor protein
chr2_+_61108702	1.832		REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr6_-_150039219	1.830		LATS1	LATS, large tumor suppressor, homolog 1 (Drosophila)
chr11_+_46299585	1.829		CREB3L1	cAMP responsive element binding protein 3-like 1
chr6_+_41514133	1.813	NM_001012426 NM_001012427 NM_138457	FOXP4	forkhead box P4
chr11_+_6625000	1.806		ILK	integrin-linked kinase
chr16_+_67571342	1.803	NM_001193524	FAM65A	family with sequence similarity 65, member A
chr19_+_48111437	1.802	NM_015711	GLTSCR1	glioma tumor suppressor candidate region gene 1
chr9_+_130860769	1.800		SLC25A25	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr21_-_47705235	1.800	NM_003906	MCM3AP	minichromosome maintenance complex component 3 associated protein
chr10_-_32667543	1.789		EPC1	enhancer of polycomb homolog 1 (Drosophila)
chr7_-_100808832	1.782	NM_003378	VGF	VGF nerve growth factor inducible
chr22_-_18484183	1.774		MICAL3	microtubule associated monoxygenase, calponin and LIM domain containing 3
chr14_+_24616095	1.764		RNF31	ring finger protein 31
chr2_-_206950895	1.763	NM_017759	INO80D	INO80 complex subunit D
chr11_+_59522801	1.759		STX3	syntaxin 3
chr6_+_138188352	1.750	NM_006290	TNFAIP3	tumor necrosis factor, alpha-induced protein 3
chr20_-_3388586	1.745		C20orf194	chromosome 20 open reading frame 194
chr2_+_43864405	1.740		PLEKHH2	pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr22_-_50708720	1.735	NM_002751	MAPK11	mitogen-activated protein kinase 11
chr2_+_61108724	1.735	NM_002908	REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr6_+_108882104	1.726		FOXO3	forkhead box O3
chr6_+_41514289	1.723		FOXP4	forkhead box P4
chr2_-_74669055	1.712	NM_001015055	RTKN	rhotekin
chr5_+_612454	1.708		CEP72	centrosomal protein 72kDa
chr12_-_15942116	1.702		EPS8	epidermal growth factor receptor pathway substrate 8
chr1_-_202129731	1.696		PTPN7	protein tyrosine phosphatase, non-receptor type 7
chr10_-_116527955	1.694		ABLIM1	actin binding LIM protein 1
chr19_+_41222915	1.686	NM_025194	ITPKC	inositol-trisphosphate 3-kinase C
chr19_-_41859830	1.686	NM_000660	TGFB1	transforming growth factor, beta 1
chr19_-_40724272	1.681	NM_152479	TTC9B	tetratricopeptide repeat domain 9B
chr19_-_1513187	1.675	NM_213604	ADAMTSL5	ADAMTS-like 5
chr12_-_15942350	1.671	NM_004447	EPS8	epidermal growth factor receptor pathway substrate 8
chr10_-_98273444	1.658	NM_012465	TLL2	tolloid-like 2
chr19_+_50094911	1.652	NM_020719	PRR12	proline rich 12
chr11_+_6625206	1.650	NM_001014795	ILK	integrin-linked kinase
chr9_-_86432546	1.644	NM_001135953 NM_025211	GKAP1	G kinase anchoring protein 1
chr13_+_42614171	1.621	NM_001204504	DGKH	diacylglycerol kinase, eta
chr20_-_3388219	1.613	NM_001009984	C20orf194	chromosome 20 open reading frame 194
chr16_-_54318889	1.606		IRX3	iroquois homeobox 3
chr5_-_150460550	1.594		TNIP1	TNFAIP3 interacting protein 1
chrX_+_153770458	1.586	NM_001099856	IKBKG	inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr5_-_150460599	1.583	NM_001252385 NM_001252386 NM_001252393 NM_006058	TNIP1	TNFAIP3 interacting protein 1
chr5_+_612404	1.581	NM_018140	CEP72	centrosomal protein 72kDa
chr17_+_26698666	1.576		SARM1	sterile alpha and TIR motif containing 1
chr6_+_36646455	1.573	NM_000389 NM_001220778	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr7_+_128312345	1.557	NM_001012454 NM_001128926	FAM71F2	family with sequence similarity 71, member F2
chr11_+_66059364	1.556	NM_153266	TMEM151A	transmembrane protein 151A
chr9_+_130860816	1.552	NM_052901 NM_001006643	SLC25A25	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr2_+_61108775	1.550		REL	v-rel reticuloendotheliosis viral oncogene homolog (avian)
chr19_+_56152281	1.548	NM_207115	ZNF580	zinc finger protein 580
chr13_+_21872248	1.545		MIPEPP3	mitochondrial intermediate peptidase pseudogene 3
chr11_-_67141008	1.540	NM_013246	CLCF1	cardiotrophin-like cytokine factor 1
chr19_+_45251933	1.539	NM_005178	BCL3	B-cell CLL/lymphoma 3
chr9_-_110251308	1.538		KLF4	Kruppel-like factor 4 (gut)
chr2_-_211035913	1.537	NM_152519	C2orf67	chromosome 2 open reading frame 67
chr5_+_172484353	1.529		C5orf41	chromosome 5 open reading frame 41
chr1_-_236030170	1.521
chr13_+_51796363	1.519	NM_001242312 NM_145019	FAM124A	family with sequence similarity 124A
chr12_-_117537090	1.515	NM_001168325 NM_017899	TESC	tescalcin
chr5_-_148758787	1.506	NM_014443	IL17B	interleukin 17B
chr4_+_139936938	1.506	NM_012118	CCRN4L	CCR4 carbon catabolite repression 4-like (S. cerevisiae)
chr9_-_110251754	1.505		KLF4	Kruppel-like factor 4 (gut)
chr17_-_18907988	1.504	NM_001039999	FAM83G	family with sequence similarity 83, member G
chr13_-_31735718	1.501		HSPH1	heat shock 105kDa/110kDa protein 1
chr17_-_44270144	1.501	NM_001193466	KIAA1267	KIAA1267
chr19_+_1067536	1.498		HMHA1	histocompatibility (minor) HA-1
chr19_+_39390567	1.489	NM_002503	NFKBIB	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
chr16_+_30676098	1.485		FBRS	fibrosin
chr20_-_50179338	1.482		NFATC2	nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chrX_-_48828250	1.471	NM_004979	KCND1	potassium voltage-gated channel, Shal-related subfamily, member 1
chr2_+_43864433	1.464	NM_172069	PLEKHH2	pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr6_-_150039391	1.464	NM_004690	LATS1	LATS, large tumor suppressor, homolog 1 (Drosophila)
chr17_-_44270255	1.463	NM_015443	KIAA1267	KIAA1267
chr11_-_63933493	1.463	NM_014067	MACROD1	MACRO domain containing 1

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
2.44	2.60e-09	GO:0051252	regulation of RNA metabolic process
2.46	4.61e-09	GO:0006355	regulation of transcription, DNA-dependent
5.72	1.96e-08	GO:0051098	regulation of binding
2.05	2.40e-08	GO:0060255	regulation of macromolecule metabolic process
6.28	2.66e-08	GO:0051101	regulation of DNA binding
6.50	4.38e-08	GO:0051090	regulation of sequence-specific DNA binding transcription factor activity
2.29	4.96e-08	GO:2000112	regulation of cellular macromolecule biosynthetic process
2.26	5.50e-08	GO:0010556	regulation of macromolecule biosynthetic process
6.39	5.98e-08	GO:0090046	regulation of transcription regulator activity
2.23	7.20e-08	GO:0010468	regulation of gene expression
1.94	2.83e-07	GO:0031323	regulation of cellular metabolic process
1.94	3.58e-07	GO:0080090	regulation of primary metabolic process
3.07	4.16e-07	GO:0010941	regulation of cell death
2.13	4.92e-07	GO:0031326	regulation of cellular biosynthetic process
2.10	6.78e-07	GO:0051171	regulation of nitrogen compound metabolic process
3.06	7.60e-07	GO:0042981	regulation of apoptosis
2.11	7.99e-07	GO:0009889	regulation of biosynthetic process
3.04	9.66e-07	GO:0043067	regulation of programmed cell death
2.10	1.32e-06	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.53	2.43e-06	GO:0050794	regulation of cellular process
1.83	2.64e-06	GO:0019222	regulation of metabolic process
2.13	4.23e-06	GO:0048522	positive regulation of cellular process
2.05	5.84e-06	GO:0048518	positive regulation of biological process
2.70	9.51e-06	GO:0002376	immune system process
2.95	1.70e-05	GO:0042127	regulation of cell proliferation
1.46	3.18e-05	GO:0050789	regulation of biological process
3.20	3.89e-05	GO:0006955	immune response
3.22	1.09e-04	GO:0002682	regulation of immune system process
2.73	2.73e-04	GO:0006357	regulation of transcription from RNA polymerase II promoter
2.99	2.89e-04	GO:0051173	positive regulation of nitrogen compound metabolic process
2.97	5.43e-04	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.09	7.31e-04	GO:0010628	positive regulation of gene expression
1.96	7.63e-04	GO:0048519	negative regulation of biological process
1.94	8.05e-04	GO:0006950	response to stress
1.38	1.26e-03	GO:0065007	biological regulation
10.01	1.43e-03	GO:0050864	regulation of B cell activation
8.14	1.83e-03	GO:0043392	negative regulation of DNA binding
3.60	1.91e-03	GO:0043066	negative regulation of apoptosis
3.93	2.08e-03	GO:0006917	induction of apoptosis
9.54	2.09e-03	GO:0034138	toll-like receptor 3 signaling pathway
2.99	2.14e-03	GO:0051254	positive regulation of RNA metabolic process
3.92	2.17e-03	GO:0012502	induction of programmed cell death
3.56	2.22e-03	GO:0043069	negative regulation of programmed cell death
3.08	2.22e-03	GO:0045893	positive regulation of transcription, DNA-dependent
7.95	2.24e-03	GO:0002224	toll-like receptor signaling pathway
2.75	2.39e-03	GO:0006952	defense response
9.24	2.67e-03	GO:0002756	MyD88-independent toll-like receptor signaling pathway
1.95	3.15e-03	GO:0048523	negative regulation of cellular process
2.32	3.18e-03	GO:0009893	positive regulation of metabolic process
7.59	3.30e-03	GO:0002221	pattern recognition receptor signaling pathway
3.46	3.41e-03	GO:0060548	negative regulation of cell death
2.39	3.60e-03	GO:0010604	positive regulation of macromolecule metabolic process
8.71	4.22e-03	GO:0034130	toll-like receptor 1 signaling pathway
8.71	4.22e-03	GO:0034134	toll-like receptor 2 signaling pathway
2.80	4.28e-03	GO:0010557	positive regulation of macromolecule biosynthetic process
7.35	4.35e-03	GO:0002758	innate immune response-activating signal transduction
8.58	4.71e-03	GO:0051092	positive regulation of NF-kappaB transcription factor activity
7.19	5.21e-03	GO:0002218	activation of innate immune response
2.18	5.26e-03	GO:0065009	regulation of molecular function
1.60	5.53e-03	GO:0051716	cellular response to stimulus
3.49	5.59e-03	GO:0008285	negative regulation of cell proliferation
1.68	6.23e-03	GO:0007165	signal transduction
3.31	6.32e-03	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
8.23	6.48e-03	GO:0002755	MyD88-dependent toll-like receptor signaling pathway
2.32	6.58e-03	GO:0031325	positive regulation of cellular metabolic process
3.18	6.63e-03	GO:0010942	positive regulation of cell death
8.12	7.18e-03	GO:0043433	negative regulation of sequence-specific DNA binding transcription factor activity
8.12	7.18e-03	GO:0090048	negative regulation of transcription regulator activity
2.57	8.23e-03	GO:0006351	transcription, DNA-dependent
7.90	8.78e-03	GO:0008063	Toll signaling pathway
7.90	8.78e-03	GO:0034142	toll-like receptor 4 signaling pathway
2.81	9.86e-03	GO:0031327	negative regulation of cellular biosynthetic process
6.63	1.02e-02	GO:0051100	negative regulation of binding
2.59	1.10e-02	GO:0031328	positive regulation of cellular biosynthetic process
5.16	1.17e-02	GO:0031349	positive regulation of defense response
3.28	1.27e-02	GO:0050776	regulation of immune response
3.04	1.29e-02	GO:0051253	negative regulation of RNA metabolic process
2.50	1.35e-02	GO:0031324	negative regulation of cellular metabolic process
3.58	1.38e-02	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
2.75	1.38e-02	GO:0009890	negative regulation of biosynthetic process
2.54	1.49e-02	GO:0009891	positive regulation of biosynthetic process
3.74	1.52e-02	GO:0031347	regulation of defense response
2.80	1.63e-02	GO:0010558	negative regulation of macromolecule biosynthetic process
3.09	1.69e-02	GO:0043065	positive regulation of apoptosis
10.99	1.84e-02	GO:0050871	positive regulation of B cell activation
3.07	1.85e-02	GO:0043068	positive regulation of programmed cell death
1.41	1.89e-02	GO:0050896	response to stimulus
4.83	2.18e-02	GO:0002757	immune response-activating signal transduction
2.18	2.43e-02	GO:0010033	response to organic substance
1.59	2.47e-02	GO:0023052	signaling
2.80	2.64e-02	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
4.72	2.71e-02	GO:0002764	immune response-regulating signaling pathway
3.21	2.99e-02	GO:0032583	regulation of gene-specific transcription
10.01	3.18e-02	GO:0002274	myeloid leukocyte activation
2.94	3.30e-02	GO:0045892	negative regulation of transcription, DNA-dependent
9.79	3.62e-02	GO:0032680	regulation of tumor necrosis factor production
5.59	4.05e-02	GO:0045089	positive regulation of innate immune response
3.13	4.09e-02	GO:0002684	positive regulation of immune system process
2.38	4.55e-02	GO:0010605	negative regulation of macromolecule metabolic process

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
60.05	2.21e-05	GO:0033256	I-kappaB/NF-kappaB complex
1.44	2.26e-03	GO:0005634	nucleus
75.06	2.56e-02	GO:0033257	Bcl3/NF-kappaB2 complex

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
3.40	5.13e-10	GO:0001071	nucleic acid binding transcription factor activity
3.40	5.13e-10	GO:0003700	sequence-specific DNA binding transcription factor activity
3.16	2.83e-05	GO:0043565	sequence-specific DNA binding
5.42	7.02e-05	GO:0005125	cytokine activity
2.45	7.76e-04	GO:0030528	transcription regulator activity
3.66	3.53e-03	GO:0016563	transcription activator activity
4.59	6.21e-03	GO:0005126	cytokine receptor binding
9.79	6.40e-03	GO:0008009	chemokine activity
1.34	6.68e-03	GO:0005515	protein binding
3.29	6.71e-03	GO:0000988	protein binding transcription factor activity
3.29	6.71e-03	GO:0000989	transcription factor binding transcription factor activity
8.83	1.16e-02	GO:0042379	chemokine receptor binding
1.73	1.48e-02	GO:0003677	DNA binding
3.10	2.36e-02	GO:0003712	transcription cofactor activity
3.42	2.58e-02	GO:0008134	transcription factor binding
3.26	4.14e-02	GO:0016564	transcription repressor activity