Motif ID: NRF1.p2

Z-value: 1.846


Transcription factors associated with NRF1.p2:

Gene SymbolEntrez IDGene Name
NRF1 4899 nuclear respiratory factor 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NRF1hg19_v1_chr7_+_129269916_1292699180.582.2e-01Click!


Activity profile for motif NRF1.p2.

activity profile for motif NRF1.p2


Sorted Z-values histogram for motif NRF1.p2

Sorted Z-values for motif NRF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NRF1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_260092 1.979 NM_001013672
C17orf97
chromosome 17 open reading frame 97
chr16_+_28565225 0.773 NM_138414
CCDC101
coiled-coil domain containing 101
chr16_+_28565279 0.745 CCDC101
coiled-coil domain containing 101
chr17_-_34257730 0.710 NM_001034836
NM_001163120
NM_001163121
NM_145654
RDM1



RAD52 motif 1



chr9_-_139981102 0.676 LOC100289341
uncharacterized LOC100289341
chr19_+_57019196 0.604 NM_020813
ZNF471
zinc finger protein 471
chr17_+_79885567 0.603 LOC92659
uncharacterized LOC92659
chr6_+_30614815 0.598 NM_001109938
NM_001161376
NM_145029
C6orf136


chromosome 6 open reading frame 136


chr9_-_139981268 0.488 LOC100289341
uncharacterized LOC100289341
chr8_+_9911797 0.430 NM_001135670
NM_012331
MSRA

methionine sulfoxide reductase A

chr1_+_226411318 0.414 NM_031944
MIXL1
Mix paired-like homeobox
chr7_-_142985270 0.397


chr13_-_49107250 0.391 NM_001268
RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr17_-_3571905 0.385 NM_001204698
NM_014604
TAX1BP3

Tax1 (human T-cell leukemia virus type I) binding protein 3

chrX_-_73512376 0.381 FTX
FTX transcript, XIST regulator (non-protein coding)
chr11_+_1331048 0.380 LOC255512
uncharacterized LOC255512
chr4_-_7044664 0.380 NM_153376
CCDC96
coiled-coil domain containing 96
chr1_-_3773620 0.367 CEP104
centrosomal protein 104kDa
chr13_-_44361032 0.366 NM_001242863
NM_017993
ENOX1

ecto-NOX disulfide-thiol exchanger 1

chr3_+_49449638 0.349 NM_022171
TCTA
T-cell leukemia translocation altered gene
chr17_-_7518124 0.337 NM_004860
FXR2
fragile X mental retardation, autosomal homolog 2
chr14_+_65879694 0.332 FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr19_-_56988698 0.318 NM_022103
ZNF667
zinc finger protein 667
chr6_-_13615386 0.316


chr4_-_184425610 0.316 LOC389247
uncharacterized LOC389247
chr2_-_74734498 0.312 PCGF1
polycomb group ring finger 1
chr13_-_49107185 0.310 RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr19_-_42721802 0.299 NM_133328
DEDD2
death effector domain containing 2
chr1_-_202858225 0.295 NM_002871
RABIF
RAB interacting factor
chr2_-_99758034 0.295 NM_182911
TSGA10
testis specific, 10
chr5_-_162887105 0.295 NM_145266
NUDCD2
NudC domain containing 2
chr3_+_49449753 0.281 TCTA
T-cell leukemia translocation altered gene
chr14_+_65879439 0.268 FUT8
fucosyltransferase 8 (alpha (1,6) fucosyltransferase)
chr1_+_76262555 0.263 NM_002440
MSH4
mutS homolog 4 (E. coli)
chr16_-_3109335 0.261 LOC100507419
uncharacterized LOC100507419
chr13_-_21348054 0.257 NM_174928
N6AMT2
N-6 adenine-specific DNA methyltransferase 2 (putative)
chr19_+_18794391 0.253 NM_001098482
NM_015321
CRTC1

CREB regulated transcription coactivator 1

chr11_+_65101345 0.252 DPF2
D4, zinc and double PHD fingers family 2
chr11_+_65101224 0.249 NM_006268
DPF2
D4, zinc and double PHD fingers family 2
chr16_-_188662 0.249 NM_001039476
NM_001077350
NM_001243247
NM_001243248
NM_001243249
NPRL3




nitrogen permease regulator-like 3 (S. cerevisiae)




chr17_-_3571819 0.245 TAX1BP3
Tax1 (human T-cell leukemia virus type I) binding protein 3
chr13_-_49107218 0.244 RCBTB2
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr5_+_176873795 0.241 NM_001174101
NM_030567
PRR7

proline rich 7 (synaptic)

chr4_-_146019296 0.239 NM_014885
ANAPC10
anaphase promoting complex subunit 10
chr21_+_46293925 0.237


chr11_-_106888829 0.237 NM_000855
GUCY1A2
guanylate cyclase 1, soluble, alpha 2
chr19_-_1592633 0.235 NM_003926
MBD3
methyl-CpG binding domain protein 3
chr16_-_30381487 0.230 NM_015527
TBC1D10B
TBC1 domain family, member 10B
chr17_-_26220372 0.228 NM_001076680
C17orf108
chromosome 17 open reading frame 108
chr7_+_113726490 0.226 FOXP2
forkhead box P2
chr17_-_7517849 0.224 FXR2
fragile X mental retardation, autosomal homolog 2
chr1_-_178062734 0.223 LOC100302401
uncharacterized LOC100302401
chr19_-_1592691 0.220 MBD3
methyl-CpG binding domain protein 3
chr6_+_8435852 0.218 LOC100506207
uncharacterized LOC100506207
chr7_+_28448970 0.216 LOC401317
uncharacterized LOC401317
chr17_-_43394326 0.216 NM_003954
MAP3K14
mitogen-activated protein kinase kinase kinase 14
chr20_+_49348050 0.213 NM_032521
PARD6B
par-6 partitioning defective 6 homolog beta (C. elegans)
chr7_-_72972021 0.206 NM_001197244
NM_001707
BCL7B

B-cell CLL/lymphoma 7B

chr20_-_10654429 0.206 NM_000214
JAG1
jagged 1
chr20_+_13976014 0.200 NM_080676
MACROD2
MACRO domain containing 2
chr17_-_15902907 0.199 NM_001042697
NM_001042698
ZSWIM7

zinc finger, SWIM-type containing 7

chrX_-_40506666 0.199 CXorf38
chromosome X open reading frame 38
chr4_+_158141735 0.198 NM_000826
NM_001083619
NM_001083620
GRIA2


glutamate receptor, ionotropic, AMPA 2


chr19_-_59066372 0.197 CHMP2A
charged multivesicular body protein 2A
chr18_-_33077896 0.196 NM_001098817
NM_194281
INO80C

INO80 complex subunit C

chr8_-_21966812 0.196 NM_024815
NUDT18
nudix (nucleoside diphosphate linked moiety X)-type motif 18
chr7_-_6388408 0.196 NM_001037163
C7orf70
chromosome 7 open reading frame 70
chr3_-_49449409 0.196 RHOA
ras homolog gene family, member A
chr11_-_64545231 0.194 NM_001178031
SF1
splicing factor 1
chr3_-_49449357 0.193 RHOA
ras homolog gene family, member A
chr2_-_139537803 0.193 NM_007226
NXPH2
neurexophilin 2
chr7_-_5569200 0.193 ACTB
actin, beta
chr3_-_49449423 0.192 RHOA
ras homolog gene family, member A
chr14_+_24521099 0.191 NM_138360
LRRC16B
leucine rich repeat containing 16B
chr7_-_6487573 0.190 NM_001142936
NM_139179
DAGLB

diacylglycerol lipase, beta

chr19_+_45971249 0.189 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr8_-_145752405 0.188 NM_001024678
LRRC24
leucine rich repeat containing 24
chr21_-_43430448 0.188 NM_001098402
NM_001098403
NM_020727
ZNF295


zinc finger protein 295


chr17_-_7760740 0.187 LSMD1
LSM domain containing 1
chr3_-_49449525 0.186 NM_001664
RHOA
ras homolog gene family, member A
chr12_-_54070108 0.186 NM_005176
ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr1_-_3773760 0.186 NM_014704
CEP104
centrosomal protein 104kDa
chr3_+_43732358 0.185 NM_016006
ABHD5
abhydrolase domain containing 5
chr3_+_106959515 0.183 LOC344595
uncharacterized LOC344595
chr6_+_14118002 0.183 CD83
CD83 molecule
chr11_+_77850824 0.183 LOC100289388
uncharacterized LOC100289388
chr19_-_56632644 0.183 NM_001002836
ZNF787
zinc finger protein 787
chr17_+_45908992 0.183 NM_033413
LRRC46
leucine rich repeat containing 46
chr3_+_44380003 0.183 C3orf23
chromosome 3 open reading frame 23
chr17_+_43971655 0.182 NM_001123066
NM_001123067
NM_001203251
NM_001203252
NM_005910
NM_016834
NM_016835
NM_016841
MAPT







microtubule-associated protein tau







chr17_-_43319100 0.179


chr19_+_18794487 0.179 CRTC1
CREB regulated transcription coactivator 1
chr19_-_4400470 0.179 NM_001199943
NM_003025
SH3GL1

SH3-domain GRB2-like 1

chr16_-_188258 0.178 NPRL3
nitrogen permease regulator-like 3 (S. cerevisiae)
chr9_-_35646802 0.177 CD72
CD72 molecule
chr7_-_156433115 0.173 C7orf13
chromosome 7 open reading frame 13
chr17_-_38256905 0.173 NM_021724
NR1D1
nuclear receptor subfamily 1, group D, member 1
chrX_+_17755562 0.172 NM_001037535
NM_001037536
NM_001037540
NM_006746
SCML1



sex comb on midleg-like 1 (Drosophila)



chr13_-_37494370 0.169 NM_001127217
NM_005905
SMAD9

SMAD family member 9

chr1_+_28879519 0.169 NM_017846
TRNAU1AP
tRNA selenocysteine 1 associated protein 1
chr19_+_54606141 0.168 NM_004542
NDUFA3
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa
chr5_-_218235 0.168 NM_145265
CCDC127
coiled-coil domain containing 127
chr1_+_24104907 0.167 PITHD1
PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1
chr19_+_59056017 0.167 TRIM28
tripartite motif containing 28
chr10_-_25304865 0.167 NM_145010
ENKUR
enkurin, TRPC channel interacting protein
chr20_-_10654139 0.166 JAG1
jagged 1
chr1_+_24104906 0.165 PITHD1
PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1
chr17_-_7155258 0.165 NM_015343
CTDNEP1
CTD nuclear envelope phosphatase 1
chr16_-_3661579 0.164 NM_032444
SLX4
SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
chr11_+_118992232 0.164 NM_001243259
NM_015517
NM_198971
HINFP


histone H4 transcription factor


chr7_-_6487508 0.164 DAGLB
diacylglycerol lipase, beta
chr17_-_7154994 0.163 NM_001143775
CTDNEP1
CTD nuclear envelope phosphatase 1
chr8_-_96281399 0.163 NM_177965
C8orf37
chromosome 8 open reading frame 37
chr19_+_2328679 0.162 SPPL2B
signal peptide peptidase-like 2B
chr9_+_110045551 0.161 RAD23B
RAD23 homolog B (S. cerevisiae)
chr3_+_44379923 0.161 NM_001029839
NM_173826
C3orf23

chromosome 3 open reading frame 23

chr5_-_132073143 0.161 NM_007054
KIF3A
kinesin family member 3A
chr10_-_16859408 0.160 NM_012425
NM_152724
RSU1

Ras suppressor protein 1

chr3_-_49449400 0.160 RHOA
ras homolog gene family, member A
chr3_-_49449393 0.159 RHOA
ras homolog gene family, member A
chr17_-_38256548 0.158 NR1D1
nuclear receptor subfamily 1, group D, member 1
chr19_+_2236815 0.158 NM_007165
SF3A2
splicing factor 3a, subunit 2, 66kDa
chr5_-_11904127 0.157 CTNND2
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr12_-_68726036 0.157 NM_001205028
NM_001205029
NM_017440
NM_020128
MDM1



Mdm1 nuclear protein homolog (mouse)



chr10_-_16859389 0.157 RSU1
Ras suppressor protein 1
chr19_-_40030759 0.156 NM_153232
EID2
EP300 interacting inhibitor of differentiation 2
chr2_-_70314065 0.156 PCBP1-AS1
PCBP1 antisense RNA 1 (non-protein coding)
chr10_-_124639077 0.156 NM_001204364
NM_152644
FAM24B-CUZD1
FAM24B

FAM24B-CUZD1 readthrough
family with sequence similarity 24, member B

chr9_-_34522972 0.155 NM_198573
ENHO
energy homeostasis associated
chr1_-_28969516 0.155 NM_001135218
NM_005644
TAF12

TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa

chr1_-_149814264 0.155 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr4_+_186317964 0.155 ANKRD37
ankyrin repeat domain 37
chr13_+_35516390 0.155 NM_015678
NBEA
neurobeachin
chr19_+_59055866 0.154 TRIM28
tripartite motif containing 28
chr19_+_2096792 0.154 NM_001031735
NM_001039846
IZUMO4

IZUMO family member 4

chr3_-_119396220 0.153 NM_005694
COX17
COX17 cytochrome c oxidase assembly homolog (S. cerevisiae)
chr19_-_44124013 0.153 NM_182498
ZNF428
zinc finger protein 428
chr22_+_26825220 0.152 NM_020437
ASPHD2
aspartate beta-hydroxylase domain containing 2
chr7_+_102004286 0.152 NM_001242713
LOC100289561
LOC100630923
uncharacterized LOC100289561
LOC100289561-PRKRIP1 readthrough
chr17_+_40811261 0.151 NM_016437
TUBG2
tubulin, gamma 2
chr3_+_49591897 0.151 NM_003458
BSN
bassoon (presynaptic cytomatrix protein)
chr11_-_59436488 0.151 NM_152716
PATL1
protein associated with topoisomerase II homolog 1 (yeast)
chr6_+_99872769 0.151


chr17_+_16120465 0.150 NM_004278
PIGL
phosphatidylinositol glycan anchor biosynthesis, class L
chr13_-_21348081 0.149 N6AMT2
N-6 adenine-specific DNA methyltransferase 2 (putative)
chr5_+_137225124 0.148 NM_014386
PKD2L2
polycystic kidney disease 2-like 2
chr7_+_100027404 0.148 MEPCE
methylphosphate capping enzyme
chr10_+_75532065 0.148 FUT11
fucosyltransferase 11 (alpha (1,3) fucosyltransferase)
chr17_+_7387688 0.148 NM_000937
POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr19_+_48867650 0.148 NM_012451
SYNGR4
synaptogyrin 4
chr12_-_49463729 0.147 NM_144593
RHEBL1
Ras homolog enriched in brain like 1
chr1_+_24104841 0.146 NM_020362
PITHD1
PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1
chr9_-_115774471 0.146 NM_001101338
ZNF883
zinc finger protein 883
chr1_-_1535446 0.146 NM_001242659
LOC643988
uncharacterized LOC643988
chr1_+_149858466 0.145 NM_003517
HIST2H2AC
histone cluster 2, H2ac
chr21_-_30257611 0.145 NM_013240
NM_182749
N6AMT1

N-6 adenine-specific DNA methyltransferase 1 (putative)

chr16_+_30710461 0.145 NM_006662
SRCAP
Snf2-related CREBBP activator protein
chr2_-_100720934 0.144 AFF3
AF4/FMR2 family, member 3
chr1_+_211556141 0.144 LINC00467
long intergenic non-protein coding RNA 467
chr7_-_150974179 0.143 NM_003078
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr17_+_7487125 0.143 MPDU1
mannose-P-dolichol utilization defect 1
chr6_-_33168438 0.143 RXRB
retinoid X receptor, beta
chr1_+_1447537 0.143 ATAD3A
ATAD3B
ATPase family, AAA domain containing 3A
ATPase family, AAA domain containing 3B
chr19_-_4400357 0.142 NM_001199944
SH3GL1
SH3-domain GRB2-like 1
chr17_+_7387773 0.142 POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr12_+_53845911 0.142 PCBP2
poly(rC) binding protein 2
chr19_+_59055826 0.140 NM_005762
TRIM28
tripartite motif containing 28
chr3_-_126373957 0.140 NM_001173513
NM_052883
TXNRD3

thioredoxin reductase 3

chr12_+_120875891 0.140 NM_004373
COX6A1
cytochrome c oxidase subunit VIa polypeptide 1
chr19_-_55769920 0.139 NM_014931
PPP6R1
protein phosphatase 6, regulatory subunit 1
chr11_+_62623466 0.139 NM_001012662
NM_001012664
NM_002394
SLC3A2


solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2


chr6_-_163148800 0.139 NM_004562
NM_013987
NM_013988
PARK2


parkinson protein 2, E3 ubiquitin protein ligase (parkin)


chr18_+_47901377 0.138 NM_001039535
NM_145060
SKA1

spindle and kinetochore associated complex subunit 1

chr5_-_11903964 0.138 NM_001332
CTNND2
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr2_+_27193448 0.137 NM_012326
MAPRE3
microtubule-associated protein, RP/EB family, member 3
chr19_+_55813601 0.137 BRSK1
BR serine/threonine kinase 1
chr18_-_47807869 0.137 MBD1
methyl-CpG binding domain protein 1
chr10_-_14879967 0.136 NM_001029954
CDNF
cerebral dopamine neurotrophic factor
chr9_-_140513222 0.136 NM_032937
C9orf37
chromosome 9 open reading frame 37
chr2_-_24346143 0.135 NM_199346
PFN4
profilin family, member 4
chr19_-_55770340 0.134 PPP6R1
protein phosphatase 6, regulatory subunit 1
chr3_+_150321065 0.134 NM_016275
SELT
selenoprotein T
chr8_+_145597718 0.133 NM_174922
ADCK5
aarF domain containing kinase 5
chr12_-_54069856 0.133 ATP5G2
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)
chr19_+_19144520 0.132 ARMC6
armadillo repeat containing 6
chr1_+_211556158 0.131 LINC00467
long intergenic non-protein coding RNA 467
chr9_+_127020586 0.131


chr19_+_47852537 0.130 NM_014681
DHX34
DEAH (Asp-Glu-Ala-His) box polypeptide 34
chr8_+_145137496 0.130 GPAA1
glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast)
chr6_+_35227300 0.130 ZNF76
zinc finger protein 76
chr19_-_5978092 0.129 RANBP3
RAN binding protein 3
chr3_+_44379590 0.129 NM_001029840
C3orf23
chromosome 3 open reading frame 23
chr7_-_102119307 0.128 NM_006234
POLR2J
polymerase (RNA) II (DNA directed) polypeptide J, 13.3kDa
chr16_-_29937354 0.128 KCTD13
potassium channel tetramerisation domain containing 13
chr1_-_227923080 0.128 NM_001161465
NM_023007
JMJD4

jumonji domain containing 4

chr9_+_110045516 0.128 NM_002874
RAD23B
RAD23 homolog B (S. cerevisiae)
chr1_+_231473681 0.127 NM_001010984
NM_032018
C1orf124

chromosome 1 open reading frame 124

chr10_-_31320772 0.127 NM_001143766
NM_001143767
NM_001143768
NM_001143770
NM_001143771
NM_182755
ZNF438





zinc finger protein 438





chr14_+_39583426 0.127 NM_001009182
NM_001009183
NM_003616
GEMIN2


gem (nuclear organelle) associated protein 2


chr1_-_236030219 0.127 NM_000081
LYST
lysosomal trafficking regulator

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.