Motif ID: PATZ1.p2

Z-value: 1.604


Transcription factors associated with PATZ1.p2:

Gene SymbolEntrez IDGene Name
PATZ1 23598 POZ (BTB) and AT hook containing zinc finger 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PATZ1hg19_v1_chr22_-_31742329_31742340-0.901.3e-02Click!


Activity profile for motif PATZ1.p2.

activity profile for motif PATZ1.p2


Sorted Z-values histogram for motif PATZ1.p2

Sorted Z-values for motif PATZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PATZ1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_1475739 2.934 NM_001114748
TMEM240
transmembrane protein 240
chr19_+_55795766 2.882 BRSK1
BR serine/threonine kinase 1
chr13_-_110438896 2.711 NM_003749
IRS2
insulin receptor substrate 2
chr1_+_212781969 2.387 NM_001040619
NM_001206484
NM_001206488
NM_001674
ATF3



activating transcription factor 3



chr8_+_22457098 2.316 NM_001013842
NM_001198827
NM_173686
C8orf58


chromosome 8 open reading frame 58


chr19_-_47734215 2.262 NM_014417
BBC3
BCL2 binding component 3
chr19_+_55795533 2.165 NM_032430
BRSK1
BR serine/threonine kinase 1
chr9_+_139221931 2.117 NM_001145638
NM_015597
GPSM1

G-protein signaling modulator 1

chr1_+_212782103 2.048 ATF3
activating transcription factor 3
chr9_-_110251754 1.954 KLF4
Kruppel-like factor 4 (gut)
chr1_-_38471170 1.857 NM_001243878
NM_004468
FHL3

four and a half LIM domains 3

chr19_-_54984341 1.789 NM_145057
CDC42EP5
CDC42 effector protein (Rho GTPase binding) 5
chr9_+_139971938 1.717 NM_207309
UAP1L1
UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr19_+_42788605 1.658 NM_015125
CIC
capicua homolog (Drosophila)
chr20_-_3388219 1.655 NM_001009984
C20orf194
chromosome 20 open reading frame 194
chr9_-_35115844 1.635 NM_025182
FAM214B
family with sequence similarity 214, member B
chr19_+_36209125 1.630 MLL4
myeloid/lymphoid or mixed-lineage leukemia 4
chr17_+_43299277 1.613 NM_005892
FMNL1
formin-like 1
chr1_+_37940129 1.559 ZC3H12A
zinc finger CCCH-type containing 12A
chr19_+_45504686 1.515 NM_006509
RELB
v-rel reticuloendotheliosis viral oncogene homolog B
chr19_-_1237840 1.515 NM_152769
C19orf26
chromosome 19 open reading frame 26
chr11_-_1593149 1.511 NM_004420
DUSP8
dual specificity phosphatase 8
chr10_+_104155431 1.508 NM_002502
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr20_-_3388586 1.465 C20orf194
chromosome 20 open reading frame 194
chr6_+_17281773 1.464 NM_001143942
RBM24
RNA binding motif protein 24
chr19_-_36523770 1.457 NM_015526
CLIP3
CAP-GLY domain containing linker protein 3
chr19_-_38878663 1.436 NM_152657
GGN
gametogenetin
chr19_-_49339667 1.432 HSD17B14
hydroxysteroid (17-beta) dehydrogenase 14
chr7_-_100493481 1.387 NM_000665
NM_015831
ACHE

acetylcholinesterase

chr11_-_67141008 1.380 NM_013246
CLCF1
cardiotrophin-like cytokine factor 1
chr8_-_103666018 1.379 NM_001032282
KLF10
Kruppel-like factor 10
chr16_+_90015138 1.378 NM_001242816
NM_001242817
NM_001242818
NM_001242820
NM_001242821
NM_001242822
NM_017702
NM_207514
DEF8







differentially expressed in FDCP 8 homolog (mouse)







chr22_-_50708720 1.377 NM_002751
MAPK11
mitogen-activated protein kinase 11
chr3_-_39195034 1.361 CSRNP1
cysteine-serine-rich nuclear protein 1
chr1_+_37940074 1.340 NM_025079
ZC3H12A
zinc finger CCCH-type containing 12A
chr3_-_39195101 1.333 NM_033027
CSRNP1
cysteine-serine-rich nuclear protein 1
chr20_-_3154169 1.330 ProSAPiP1
ProSAPiP1 protein
chr19_+_36208917 1.325 NM_014727
MLL4
myeloid/lymphoid or mixed-lineage leukemia 4
chr5_+_172484353 1.311 C5orf41
chromosome 5 open reading frame 41
chr6_-_91006460 1.306 NM_021813
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr19_+_56652689 1.300 ZNF444
zinc finger protein 444
chr19_-_4065467 1.297 ZBTB7A
zinc finger and BTB domain containing 7A
chr1_+_37940180 1.282 ZC3H12A
zinc finger CCCH-type containing 12A
chr6_-_91006580 1.245 NM_001170794
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr19_+_56652529 1.240 NM_001253792
NM_018337
ZNF444

zinc finger protein 444

chr10_+_135192694 1.234 NM_152911
NM_207127
NM_207128
PAOX


polyamine oxidase (exo-N4-amino)


chr1_+_201857789 1.224 NM_198149
SHISA4
shisa homolog 4 (Xenopus laevis)
chr19_-_36523540 1.224 NM_001199570
CLIP3
CAP-GLY domain containing linker protein 3
chr6_+_37137882 1.220 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr12_+_133195365 1.199 NM_012226
NM_016318
NM_170682
NM_170683
NM_174872
NM_174873
P2RX2





purinergic receptor P2X, ligand-gated ion channel, 2





chr14_-_71275732 1.191 NM_033141
MAP3K9
mitogen-activated protein kinase kinase kinase 9
chr13_+_52027435 1.185


chr9_-_110252045 1.180 NM_004235
KLF4
Kruppel-like factor 4 (gut)
chr16_+_90015827 1.174 NM_001242819
DEF8
differentially expressed in FDCP 8 homolog (mouse)
chr9_+_139972195 1.172 UAP1L1
UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr17_+_7758380 1.171 NM_203411
TMEM88
transmembrane protein 88
chr17_-_74497406 1.167 NM_024599
RHBDF2
rhomboid 5 homolog 2 (Drosophila)
chr7_+_1570321 1.164 NM_002360
MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr8_-_29207795 1.160 NM_001394
DUSP4
dual specificity phosphatase 4
chr12_-_57914287 1.150 NM_001195053
NM_001195054
NM_001195055
NM_001195056
NM_001195057
NM_004083
DDIT3





DNA-damage-inducible transcript 3





chr11_+_560868 1.143 NM_001143993
RASSF7
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr19_+_496453 1.130 NM_130760
NM_130762
MADCAM1

mucosal vascular addressin cell adhesion molecule 1

chr19_+_55813393 1.128 BRSK1
BR serine/threonine kinase 1
chr19_+_47759802 1.120 CCDC9
coiled-coil domain containing 9
chr12_-_49182718 1.061 NM_020983
ADCY6
adenylate cyclase 6
chr22_-_20004251 1.055 NM_001670
ARVCF
armadillo repeat gene deleted in velocardiofacial syndrome
chr22_+_38597938 1.048 NM_001161572
NM_001161574
NM_012323
MAFF


v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)


chr16_-_52580805 1.044 NM_001080430
TOX3
TOX high mobility group box family member 3
chr19_-_1513187 1.041 NM_213604
ADAMTSL5
ADAMTS-like 5
chr8_-_144650998 1.027 C8orf73
chromosome 8 open reading frame 73
chr19_+_55813601 1.026 BRSK1
BR serine/threonine kinase 1
chr12_-_51611476 1.020 POU6F1
POU class 6 homeobox 1
chr1_+_45266048 1.016 PLK3
polo-like kinase 3
chr6_-_44233244 1.014 NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr16_+_67562704 1.009 NM_024519
NM_001193522
FAM65A

family with sequence similarity 65, member A

chr19_+_41305333 1.008 NM_053046
EGLN2
egl nine homolog 2 (C. elegans)
chr14_+_75745480 1.007 NM_005252
FOS
FBJ murine osteosarcoma viral oncogene homolog
chr1_+_45265896 0.991 PLK3
polo-like kinase 3
chr8_+_81398416 0.975 NM_001105539
NM_023929
ZBTB10

zinc finger and BTB domain containing 10

chr6_+_33387846 0.972 NM_006772
SYNGAP1
synaptic Ras GTPase activating protein 1
chr16_-_30107492 0.966 NM_031477
NM_001145524
YPEL3

yippee-like 3 (Drosophila)

chr19_-_45908288 0.963 NM_006663
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr22_+_38598065 0.954 MAFF
v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr16_-_89768094 0.954 NM_152339
SPATA2L
spermatogenesis associated 2-like
chr1_+_35331533 0.950


chr19_+_47759730 0.948 NM_015603
CCDC9
coiled-coil domain containing 9
chr19_+_35491225 0.946 NM_001136199
NM_020895
GRAMD1A

GRAM domain containing 1A

chr16_-_57570455 0.945 NM_033212
CCDC102A
coiled-coil domain containing 102A
chr17_-_76356153 0.943 NM_003955
SOCS3
suppressor of cytokine signaling 3
chr10_-_79686279 0.942 NM_004747
DLG5
discs, large homolog 5 (Drosophila)
chr7_+_106809405 0.935 NM_001244262
NM_012257
HBP1

HMG-box transcription factor 1

chr8_+_144329105 0.932 NM_173832
ZFP41
zinc finger protein 41 homolog (mouse)
chr12_-_112036867 0.921 ATXN2
ataxin 2
chr17_+_81037504 0.918 NM_001004431
METRNL
meteorin, glial cell differentiation regulator-like
chr17_+_36861398 0.915 MLLT6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr12_+_106696508 0.915 NM_152772
TCP11L2
t-complex 11 (mouse)-like 2
chr3_-_114866090 0.913 NM_015642
ZBTB20
zinc finger and BTB domain containing 20
chr19_-_7701852 0.912


chr19_-_11373117 0.897 NM_020812
DOCK6
dedicator of cytokinesis 6
chr1_+_201857997 0.896 SHISA4
shisa homolog 4 (Xenopus laevis)
chr19_+_41305100 0.891 EGLN2
egl nine homolog 2 (C. elegans)
chr2_-_211035913 0.888 NM_152519
C2orf67
chromosome 2 open reading frame 67
chrX_+_153665468 0.888 GDI1
GDP dissociation inhibitor 1
chr19_+_49622480 0.884 NM_003660
PPFIA3
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr16_-_71917880 0.870 NM_001201552
NM_001201554
NM_001201556
ZNF821


zinc finger protein 821


chr20_-_62601140 0.869 NM_020713
ZNF512B
zinc finger protein 512B
chrX_-_48828250 0.860 NM_004979
KCND1
potassium voltage-gated channel, Shal-related subfamily, member 1
chr19_-_2721337 0.859 NM_145173
DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr20_-_56884488 0.858 PPP4R1L
protein phosphatase 4, regulatory subunit 1-like
chr12_-_112036257 0.856 ATXN2
ataxin 2
chr16_-_30381487 0.855 NM_015527
TBC1D10B
TBC1 domain family, member 10B
chr1_+_45266035 0.845 NM_004073
PLK3
polo-like kinase 3
chr17_-_42201009 0.845 NM_001015053
NM_005474
HDAC5

histone deacetylase 5

chr2_+_28616360 0.843 FOSL2
FOS-like antigen 2
chr20_-_62711160 0.839 NM_001039467
RGS19
regulator of G-protein signaling 19
chr1_-_228135587 0.833 NM_003395
WNT9A
wingless-type MMTV integration site family, member 9A
chr15_-_60884615 0.833 NM_134262
RORA
RAR-related orphan receptor A
chr1_+_28585959 0.832 NM_031459
SESN2
sestrin 2
chr3_-_129830320 0.827


chr16_+_1203240 0.826 NM_001005407
NM_021098
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr12_+_57482922 0.820 NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr11_-_6676851 0.819 NM_003737
DCHS1
dachsous 1 (Drosophila)
chr15_-_65360297 0.819 NM_016563
RASL12
RAS-like, family 12
chr17_-_42200957 0.818 HDAC5
histone deacetylase 5
chr15_+_40733302 0.809 NM_014952
BAHD1
bromo adjacent homology domain containing 1
chr2_+_10183630 0.803 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr5_+_137673956 0.802 FAM53C
family with sequence similarity 53, member C
chr7_+_100081549 0.798 NM_173564
NYAP1
neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adaptor 1
chr19_-_4066739 0.797 NM_015898
ZBTB7A
zinc finger and BTB domain containing 7A
chr7_+_64498643 0.792 CCT6P3
chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chrX_-_103087106 0.792 NM_016370
RAB9B
RAB9B, member RAS oncogene family
chr15_-_61521416 0.785 RORA
RAR-related orphan receptor A
chr11_+_61735217 0.782 LOC399900
uncharacterized LOC399900
chr11_+_64073040 0.781 NM_004451
ESRRA
estrogen-related receptor alpha
chr5_-_1112106 0.781 NM_006598
SLC12A7
solute carrier family 12 (potassium/chloride transporters), member 7
chr9_+_140500054 0.779 NM_152285
ARRDC1
arrestin domain containing 1
chr11_+_57228126 0.775 NM_178570
RTN4RL2
reticulon 4 receptor-like 2
chr3_+_119421865 0.775 NM_033364
C3orf15
chromosome 3 open reading frame 15
chr12_+_57482886 0.773 NAB2
NGFI-A binding protein 2 (EGR1 binding protein 2)
chr19_+_41305041 0.772 NM_080732
EGLN2
egl nine homolog 2 (C. elegans)
chr6_-_143266283 0.771 NM_006734
HIVEP2
human immunodeficiency virus type I enhancer binding protein 2
chr5_+_137673702 0.770 NM_016605
FAM53C
family with sequence similarity 53, member C
chr21_-_37528578 0.767 LOC100506428
uncharacterized LOC100506428
chr14_-_24020766 0.764 NM_033400
ZFHX2
zinc finger homeobox 2
chr7_+_102073953 0.763 NM_001126340
NM_032831
ORAI2

ORAI calcium release-activated calcium modulator 2

chr16_-_755718 0.763 NM_153350
FBXL16
F-box and leucine-rich repeat protein 16
chr19_+_13906207 0.762 NM_023072
ZSWIM4
zinc finger, SWIM-type containing 4
chr16_-_75299713 0.760 NM_001170720
NM_001170714
NM_001170718
BCAR1


breast cancer anti-estrogen resistance 1


chr8_+_144328990 0.760 ZFP41
zinc finger protein 41 homolog (mouse)
chr19_+_39897457 0.760 NM_003407
ZFP36
zinc finger protein 36, C3H type, homolog (mouse)
chr6_-_30655078 0.753 NM_001134870
PPP1R18
protein phosphatase 1, regulatory subunit 18
chr5_-_139725860 0.751 HBEGF
heparin-binding EGF-like growth factor
chr9_+_140500097 0.751 ARRDC1
arrestin domain containing 1
chr20_-_62205559 0.747 NM_001037335
PRIC285
peroxisomal proliferator-activated receptor A interacting complex 285
chr7_-_98741375 0.746 SMURF1
SMAD specific E3 ubiquitin protein ligase 1
chr8_+_128806720 0.737 PVT1
Pvt1 oncogene (non-protein coding)
chr16_-_68002455 0.736 NM_001145961
NM_001145962
NM_005072
SLC12A4


solute carrier family 12 (potassium/chloride transporters), member 4


chr19_+_45971249 0.735 NM_001114171
NM_006732
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr16_+_89894853 0.732 NM_032451
SPIRE2
spire homolog 2 (Drosophila)
chr4_-_186392847 0.730 NM_001145411
NM_152775
CCDC110

coiled-coil domain containing 110

chr6_-_30654978 0.728 PPP1R18
protein phosphatase 1, regulatory subunit 18
chr14_+_21538339 0.725 NM_018071
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr22_+_51039178 0.725 MAPK8IP2
mitogen-activated protein kinase 8 interacting protein 2
chr16_-_402398 0.724 AXIN1
axin 1
chr19_+_48673936 0.723 C19orf68
chromosome 19 open reading frame 68
chr7_+_73082157 0.722 NM_001077621
VPS37D
vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr5_+_137673953 0.722 FAM53C
family with sequence similarity 53, member C
chr1_-_38273852 0.721 NM_024640
YRDC
yrdC domain containing (E. coli)
chr2_+_11295539 0.720 NM_152391
PQLC3
PQ loop repeat containing 3
chr22_-_41842766 0.720 TOB2
transducer of ERBB2, 2
chr6_-_44233499 0.720 NM_004556
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr11_+_45907198 0.719 MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr5_+_141016516 0.719 NM_001130029
NM_173828
RELL2

RELT-like 2

chr7_+_28448970 0.714 LOC401317
uncharacterized LOC401317
chr3_+_50192420 0.711 SEMA3F
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F
chr1_-_38273823 0.704 YRDC
yrdC domain containing (E. coli)
chr19_-_31840118 0.704 NM_020856
TSHZ3
teashirt zinc finger homeobox 3
chr14_-_21566497 0.701 ZNF219
zinc finger protein 219
chr1_-_38273683 0.700 YRDC
yrdC domain containing (E. coli)
chr19_+_47778099 0.696 NM_178511
PRR24
proline rich 24
chr19_-_49339913 0.696 NM_016246
HSD17B14
hydroxysteroid (17-beta) dehydrogenase 14
chr19_-_44008984 0.692 NM_198850
PHLDB3
pleckstrin homology-like domain, family B, member 3
chr8_+_144329197 0.691 ZFP41
zinc finger protein 41 homolog (mouse)
chr19_-_51893791 0.690 NM_001193623
LOC147646
uncharacterized LOC147646
chr7_+_102074002 0.690 ORAI2
ORAI calcium release-activated calcium modulator 2
chr12_+_50017340 0.690 NM_012272
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr1_-_38273846 0.687 YRDC
yrdC domain containing (E. coli)
chr19_-_344778 0.686 NM_017550
MIER2
mesoderm induction early response 1, family member 2
chr5_+_141016987 0.685 RELL2
RELT-like 2
chr17_-_41910439 0.684 NM_001932
MPP3
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
chr2_+_30369868 0.683 YPEL5
yippee-like 5 (Drosophila)
chr4_-_967269 0.679 DGKQ
diacylglycerol kinase, theta 110kDa
chr20_+_35974458 0.678 NM_198291
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr19_+_4969126 0.677 KDM4B
lysine (K)-specific demethylase 4B
chr16_-_402617 0.671 NM_003502
NM_181050
AXIN1

axin 1

chr14_-_21566728 0.671 NM_016423
ZNF219
zinc finger protein 219
chr19_+_35491329 0.671 GRAMD1A
GRAM domain containing 1A
chr6_+_108882068 0.671 NM_001455
FOXO3
forkhead box O3
chr22_+_31477231 0.670 NM_006932
NM_134269
NM_134270
SMTN


smoothelin


chr8_-_145047639 0.670 NM_201378
PLEC
plectin

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.87 3.53e-06 GO:0060255 regulation of macromolecule metabolic process
2.52 3.49e-05 GO:0019222 regulation of metabolic process
2.63 5.46e-05 GO:0080090 regulation of primary metabolic process
2.60 7.37e-05 GO:0031323 regulation of cellular metabolic process
2.93 1.59e-03 GO:0051252 regulation of RNA metabolic process
2.70 1.67e-03 GO:0048518 positive regulation of biological process
4.52 3.33e-03 GO:0006351 transcription, DNA-dependent
2.28 3.51e-03 GO:0032502 developmental process
2.90 3.69e-03 GO:0006355 regulation of transcription, DNA-dependent
2.75 4.33e-03 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.61 5.23e-03 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.61 5.23e-03 GO:0031326 regulation of cellular biosynthetic process
1.75 5.51e-03 GO:0050794 regulation of cellular process
2.59 6.23e-03 GO:0009889 regulation of biosynthetic process
2.68 6.44e-03 GO:0010556 regulation of macromolecule biosynthetic process
2.31 7.76e-03 GO:0007275 multicellular organismal development
1.70 7.90e-03 GO:0050789 regulation of biological process
2.54 8.34e-03 GO:0051171 regulation of nitrogen compound metabolic process
4.08 9.36e-03 GO:0032774 RNA biosynthetic process
2.60 1.00e-02 GO:0010468 regulation of gene expression
13.86 1.04e-02 GO:0031098 stress-activated protein kinase signaling cascade
18.83 2.11e-02 GO:0034138 toll-like receptor 3 signaling pathway
18.25 2.39e-02 GO:0002756 MyD88-independent toll-like receptor signaling pathway
17.19 3.02e-02 GO:0034130 toll-like receptor 1 signaling pathway
17.19 3.02e-02 GO:0034134 toll-like receptor 2 signaling pathway
16.25 3.76e-02 GO:0002755 MyD88-dependent toll-like receptor signaling pathway
1.59 4.35e-02 GO:0065007 biological regulation
15.61 4.40e-02 GO:0008063 Toll signaling pathway
15.61 4.40e-02 GO:0034142 toll-like receptor 4 signaling pathway
7.68 4.41e-02 GO:0000165 MAPKKK cascade

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
4.80 1.72e-05 GO:0001071 nucleic acid binding transcription factor activity
4.80 1.72e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
4.63 3.28e-03 GO:0043565 sequence-specific DNA binding
2.60 3.33e-03 GO:0003677 DNA binding