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• Activity deltas table
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Motif ID: SP1.p2

Z-value: 2.208

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr13_-_110438896	3.872	NM_003749	IRS2	insulin receptor substrate 2
chr1_+_212781969	3.148	NM_001040619 NM_001206484 NM_001206488 NM_001674	ATF3	activating transcription factor 3
chr19_-_10679328	3.037		CDKN2D	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr10_+_135192694	3.001	NM_152911 NM_207127 NM_207128	PAOX	polyamine oxidase (exo-N4-amino)
chr19_-_47734215	2.954	NM_014417	BBC3	BCL2 binding component 3
chr9_+_139972195	2.776		UAP1L1	UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr1_-_935469	2.751	NM_001142467 NM_021170	HES4	hairy and enhancer of split 4 (Drosophila)
chr9_-_110251754	2.724		KLF4	Kruppel-like factor 4 (gut)
chr21_-_37528578	2.723		LOC100506428	uncharacterized LOC100506428
chr1_-_38471170	2.710	NM_001243878 NM_004468	FHL3	four and a half LIM domains 3
chr10_+_104155431	2.654	NM_002502	NFKB2	nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr1_+_212782103	2.561		ATF3	activating transcription factor 3
chr8_+_22457098	2.457	NM_001013842 NM_001198827 NM_173686	C8orf58	chromosome 8 open reading frame 58
chr22_-_50708720	2.369	NM_002751	MAPK11	mitogen-activated protein kinase 11
chr6_+_37137882	2.349	NM_001243186 NM_002648	PIM1	pim-1 oncogene
chr9_-_140317583	2.321		EXD3	exonuclease 3'-5' domain containing 3
chr19_-_49339667	2.276		HSD17B14	hydroxysteroid (17-beta) dehydrogenase 14
chr19_+_42788605	2.271	NM_015125	CIC	capicua homolog (Drosophila)
chr14_+_75745480	2.269	NM_005252	FOS	FBJ murine osteosarcoma viral oncogene homolog
chr16_+_1203240	2.266	NM_001005407 NM_021098	CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit
chr16_-_402617	2.261	NM_003502 NM_181050	AXIN1	axin 1
chr19_+_41305100	2.175		EGLN2	egl nine homolog 2 (C. elegans)
chr19_+_45504686	2.161	NM_006509	RELB	v-rel reticuloendotheliosis viral oncogene homolog B
chr6_-_91006460	2.132	NM_021813	BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr9_+_139221931	2.072	NM_001145638 NM_015597	GPSM1	G-protein signaling modulator 1
chr17_+_43299277	2.068	NM_005892	FMNL1	formin-like 1
chr12_-_57914287	2.035	NM_001195053 NM_001195054 NM_001195055 NM_001195056 NM_001195057 NM_004083	DDIT3	DNA-damage-inducible transcript 3
chr19_-_10679620	2.010	NM_001800 NM_079421	CDKN2D	cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr12_+_57482886	2.009		NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)
chr19_+_41305333	1.986	NM_053046	EGLN2	egl nine homolog 2 (C. elegans)
chr19_-_45681454	1.978	NM_024108	TRAPPC6A	trafficking protein particle complex 6A
chr19_+_41305041	1.969	NM_080732	EGLN2	egl nine homolog 2 (C. elegans)
chr19_-_12886263	1.927		HOOK2	hook homolog 2 (Drosophila)
chr6_-_41702734	1.920	NM_007162	TFEB	transcription factor EB
chr5_+_172484353	1.917		C5orf41	chromosome 5 open reading frame 41
chr19_-_4065467	1.915		ZBTB7A	zinc finger and BTB domain containing 7A
chr19_+_55795766	1.912		BRSK1	BR serine/threonine kinase 1
chr1_+_201857997	1.910		SHISA4	shisa homolog 4 (Xenopus laevis)
chr20_-_3388219	1.901	NM_001009984	C20orf194	chromosome 20 open reading frame 194
chr7_+_28448970	1.880		LOC401317	uncharacterized LOC401317
chr19_-_50143350	1.869	NM_006270	RRAS	related RAS viral (r-ras) oncogene homolog
chr1_+_201857789	1.867	NM_198149	SHISA4	shisa homolog 4 (Xenopus laevis)
chr20_-_3154169	1.856		ProSAPiP1	ProSAPiP1 protein
chr7_-_100493481	1.852	NM_000665 NM_015831	ACHE	acetylcholinesterase
chr17_-_74497406	1.841	NM_024599	RHBDF2	rhomboid 5 homolog 2 (Drosophila)
chr2_+_28616360	1.835		FOSL2	FOS-like antigen 2
chr7_+_1570321	1.827	NM_002360	MAFK	v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr17_-_72968790	1.821	NM_030630	C17orf28	chromosome 17 open reading frame 28
chr6_+_17281773	1.818	NM_001143942	RBM24	RNA binding motif protein 24
chr9_+_139971938	1.812	NM_207309	UAP1L1	UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr1_+_37940129	1.791		ZC3H12A	zinc finger CCCH-type containing 12A
chr1_+_37940180	1.788		ZC3H12A	zinc finger CCCH-type containing 12A
chr16_-_89768094	1.776	NM_152339	SPATA2L	spermatogenesis associated 2-like
chr3_-_114866090	1.768	NM_015642	ZBTB20	zinc finger and BTB domain containing 20
chr8_+_144328990	1.764		ZFP41	zinc finger protein 41 homolog (mouse)
chr16_-_2185824	1.762	NM_000296 NM_001009944	PKD1	polycystic kidney disease 1 (autosomal dominant)
chr1_+_37940074	1.758	NM_025079	ZC3H12A	zinc finger CCCH-type containing 12A
chr17_-_72968750	1.752
chr2_+_10183630	1.745	NM_003597 NM_001177716	KLF11	Kruppel-like factor 11
chr19_+_7660698	1.742	NM_001080429 NM_020902	CAMSAP3	calmodulin regulated spectrin-associated protein family, member 3
chr1_-_1475739	1.723	NM_001114748	TMEM240	transmembrane protein 240
chr22_+_51039178	1.712		MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2
chr16_+_1203737	1.708		CACNA1H	calcium channel, voltage-dependent, T type, alpha 1H subunit
chr16_-_57570455	1.698	NM_033212	CCDC102A	coiled-coil domain containing 102A
chr9_-_35115844	1.697	NM_025182	FAM214B	family with sequence similarity 214, member B
chr19_-_31840118	1.694	NM_020856	TSHZ3	teashirt zinc finger homeobox 3
chr22_-_20004251	1.691	NM_001670	ARVCF	armadillo repeat gene deleted in velocardiofacial syndrome
chr1_-_935352	1.672		HES4	hairy and enhancer of split 4 (Drosophila)
chr19_+_45971249	1.655	NM_001114171 NM_006732	FOSB	FBJ murine osteosarcoma viral oncogene homolog B
chr2_-_145274916	1.637		ZEB2	zinc finger E-box binding homeobox 2
chr16_+_776957	1.634	NM_032304	HAGHL	hydroxyacylglutathione hydrolase-like
chr19_-_1237840	1.627	NM_152769	C19orf26	chromosome 19 open reading frame 26
chr19_+_41284161	1.624		RAB4B-EGLN2 RAB4B	RAB4B-EGLN2 readthrough RAB4B, member RAS oncogene family
chr1_+_45266048	1.619		PLK3	polo-like kinase 3
chr19_+_36208917	1.614	NM_014727	MLL4	myeloid/lymphoid or mixed-lineage leukemia 4
chr8_-_103666018	1.610	NM_001032282	KLF10	Kruppel-like factor 10
chr16_-_402398	1.609		AXIN1	axin 1
chr12_-_49182718	1.605	NM_020983	ADCY6	adenylate cyclase 6
chr1_+_45265896	1.603		PLK3	polo-like kinase 3
chr2_+_28615695	1.584		FOSL2	FOS-like antigen 2
chr11_-_1593149	1.563	NM_004420	DUSP8	dual specificity phosphatase 8
chr19_+_13906207	1.556	NM_023072	ZSWIM4	zinc finger, SWIM-type containing 4
chr19_-_49339913	1.547	NM_016246	HSD17B14	hydroxysteroid (17-beta) dehydrogenase 14
chr14_-_71275732	1.535	NM_033141	MAP3K9	mitogen-activated protein kinase kinase kinase 9
chr19_+_36209125	1.523		MLL4	myeloid/lymphoid or mixed-lineage leukemia 4
chr2_+_149633173	1.512
chr16_-_29606639	1.508
chr12_+_133195365	1.500	NM_012226 NM_016318 NM_170682 NM_170683 NM_174872 NM_174873	P2RX2	purinergic receptor P2X, ligand-gated ion channel, 2
chr1_+_233463513	1.498	NM_032435	KIAA1804	mixed lineage kinase 4
chr19_+_48972574	1.495		CYTH2	cytohesin 2
chr22_-_20427814	1.493		PI4KAP1	phosphatidylinositol 4-kinase, catalytic, alpha pseudogene 1
chr17_-_63557615	1.488	NM_004655	AXIN2	axin 2
chr22_+_50354428	1.481		PIM3	pim-3 oncogene
chr11_-_33722285	1.480	NM_001166692	C11orf91	chromosome 11 open reading frame 91
chr20_-_3388586	1.472		C20orf194	chromosome 20 open reading frame 194
chr16_-_29466284	1.470	NM_001031827 NM_001039182	BOLA2 BOLA2B	bolA homolog 2 (E. coli) bolA homolog 2B (E. coli)
chr17_+_27920479	1.461	NM_152345	ANKRD13B	ankyrin repeat domain 13B
chr12_+_52400725	1.459	NM_181711	GRASP	GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr22_+_51039100	1.451	NM_012324	MAPK8IP2	mitogen-activated protein kinase 8 interacting protein 2
chr22_+_38597938	1.448	NM_001161572 NM_001161574 NM_012323	MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr20_+_4129409	1.443	NM_175839 NM_175840 NM_175841 NM_175842	SMOX	spermine oxidase
chr2_+_28615771	1.442	NM_005253	FOSL2	FOS-like antigen 2
chr19_+_56652529	1.440	NM_001253792 NM_018337	ZNF444	zinc finger protein 444
chr8_+_8086103	1.439		FLJ10661	family with sequence similarity 86, member A pseudogene
chr19_+_35491329	1.433		GRAMD1A	GRAM domain containing 1A
chr12_+_57482674	1.427	NM_005967	NAB2	NGFI-A binding protein 2 (EGR1 binding protein 2)
chr19_-_4867705	1.424	NM_001164189 NM_001164194 NM_005817	PLIN3	perilipin 3
chr17_-_41910439	1.423	NM_001932	MPP3	membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
chr2_+_28616346	1.412		FOSL2	FOS-like antigen 2
chr17_+_36861398	1.406		MLLT6	myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr16_-_29606286	1.399		LOC440354	smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans) pseudogene
chr2_+_28615668	1.399		FOSL2	FOS-like antigen 2
chr6_-_91006580	1.397	NM_001170794	BACH2	BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr7_-_98741375	1.382		SMURF1	SMAD specific E3 ubiquitin protein ligase 1
chr19_-_460995	1.380	NM_012435	SHC2	SHC (Src homology 2 domain containing) transforming protein 2
chr3_-_39195034	1.379		CSRNP1	cysteine-serine-rich nuclear protein 1
chr19_+_35491225	1.377	NM_001136199 NM_020895	GRAMD1A	GRAM domain containing 1A
chr1_+_45266035	1.377	NM_004073	PLK3	polo-like kinase 3
chr3_+_184097860	1.368	NM_003741	CHRD	chordin
chr22_+_31477231	1.362	NM_006932 NM_134269 NM_134270	SMTN	smoothelin
chr4_-_967269	1.361		DGKQ	diacylglycerol kinase, theta 110kDa
chr10_-_31320772	1.356	NM_001143766 NM_001143767 NM_001143768 NM_001143770 NM_001143771 NM_182755	ZNF438	zinc finger protein 438
chr3_-_39195101	1.355	NM_033027	CSRNP1	cysteine-serine-rich nuclear protein 1
chr11_+_64073040	1.355	NM_004451	ESRRA	estrogen-related receptor alpha
chr17_+_7255207	1.355	NM_001002914	KCTD11	potassium channel tetramerisation domain containing 11
chr19_+_56652689	1.337		ZNF444	zinc finger protein 444
chr19_+_4969123	1.332	NM_015015	KDM4B	lysine (K)-specific demethylase 4B
chr8_+_144329197	1.329		ZFP41	zinc finger protein 41 homolog (mouse)
chr17_+_79989485	1.326	NM_005052	RAC3	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr8_+_81398416	1.320	NM_001105539 NM_023929	ZBTB10	zinc finger and BTB domain containing 10
chr19_+_2164119	1.319	NM_032482	DOT1L	DOT1-like, histone H3 methyltransferase (S. cerevisiae)
chr7_+_64498643	1.319		CCT6P3	chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chr22_+_38598065	1.317		MAFF	v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr19_+_55795533	1.317	NM_032430	BRSK1	BR serine/threonine kinase 1
chr20_-_62711160	1.315	NM_001039467	RGS19	regulator of G-protein signaling 19
chr22_-_41032684	1.313	NM_020831	MKL1	megakaryoblastic leukemia (translocation) 1
chr19_+_47759802	1.312		CCDC9	coiled-coil domain containing 9
chr16_-_122573	1.311	NM_022450	RHBDF1	rhomboid 5 homolog 1 (Drosophila)
chr6_-_43596919	1.305	NM_019096	GTPBP2	GTP binding protein 2
chr6_-_33285493	1.304	NM_005453	ZBTB22	zinc finger and BTB domain containing 22
chr10_-_126849066	1.303	NM_001329	CTBP2	C-terminal binding protein 2
chr19_-_4867638	1.303		PLIN3	perilipin 3
chr2_+_42275017	1.300	NM_138370	PKDCC	protein kinase domain containing, cytoplasmic homolog (mouse)
chr11_-_46142955	1.297	NM_001101802 NM_016621	PHF21A	PHD finger protein 21A
chr17_-_43394326	1.297	NM_003954	MAP3K14	mitogen-activated protein kinase kinase kinase 14
chr19_-_4867655	1.295		PLIN3	perilipin 3
chr17_+_26698666	1.295		SARM1	sterile alpha and TIR motif containing 1
chr15_+_41136622	1.293	NM_001032367	SPINT1	serine peptidase inhibitor, Kunitz type 1
chr1_-_16302272	1.291	NM_001242884 NM_003443	ZBTB17	zinc finger and BTB domain containing 17
chr8_-_103667882	1.286	NM_005655	KLF10	Kruppel-like factor 10
chr22_-_41032623	1.285		MKL1	megakaryoblastic leukemia (translocation) 1
chr20_-_31172874	1.285		LOC284804	uncharacterized LOC284804
chr17_-_63557764	1.279		AXIN2	axin 2
chrX_+_153665258	1.274	NM_001493	GDI1	GDP dissociation inhibitor 1
chr19_-_344778	1.270	NM_017550	MIER2	mesoderm induction early response 1, family member 2
chr6_-_33285718	1.268	NM_001145338	ZBTB22	zinc finger and BTB domain containing 22
chr17_-_80231240	1.260		CSNK1D	casein kinase 1, delta
chr7_-_86974693	1.256		TP53TG1	TP53 target 1 (non-protein coding)
chr5_+_172483285	1.255	NM_001168393 NM_001168394 NM_153607	C5orf41	chromosome 5 open reading frame 41
chr17_-_42277319	1.255		ATXN7L3	ataxin 7-like 3
chr8_+_144329105	1.255	NM_173832	ZFP41	zinc finger protein 41 homolog (mouse)
chr9_-_110252045	1.254	NM_004235	KLF4	Kruppel-like factor 4 (gut)
chr16_+_66638632	1.254		CMTM3	CKLF-like MARVEL transmembrane domain containing 3
chr19_+_49375677	1.248		PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr5_+_179234002	1.238	NM_001142299	SQSTM1	sequestosome 1
chr9_+_130159383	1.234	NM_014580	SLC2A8	solute carrier family 2 (facilitated glucose transporter), member 8
chr6_+_33387846	1.234	NM_006772	SYNGAP1	synaptic Ras GTPase activating protein 1
chr19_+_49375679	1.233		PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr9_-_35111534	1.229		FAM214B	family with sequence similarity 214, member B
chr19_+_36266366	1.220	NM_001172630 NM_052948	ARHGAP33	Rho GTPase activating protein 33
chr6_+_2245965	1.217
chr12_+_132379262	1.214	NM_003565	ULK1	unc-51-like kinase 1 (C. elegans)
chr1_+_68151092	1.213		GADD45A	growth arrest and DNA-damage-inducible, alpha
chr19_-_1174263	1.212	NM_014963	SBNO2	strawberry notch homolog 2 (Drosophila)
chr11_-_67141008	1.202	NM_013246	CLCF1	cardiotrophin-like cytokine factor 1
chr11_-_61684981	1.201	NM_013401	RAB3IL1	RAB3A interacting protein (rabin3)-like 1
chr6_+_43738757	1.201		VEGFA	vascular endothelial growth factor A
chr19_-_46000159	1.200	NM_005619 NM_206900	RTN2	reticulon 2
chr7_+_18126543	1.197	NM_001204144	HDAC9	histone deacetylase 9
chr7_+_150076405	1.197	NM_173680	ZNF775	zinc finger protein 775
chr19_+_49375638	1.196	NM_014330	PPP1R15A	protein phosphatase 1, regulatory subunit 15A
chr16_+_89787951	1.196	NM_001113525	ZNF276	zinc finger protein 276
chr19_+_48673936	1.191		C19orf68	chromosome 19 open reading frame 68
chr12_-_26277807	1.190	NM_030762	BHLHE41	basic helix-loop-helix family, member e41
chr16_+_67562704	1.186	NM_024519 NM_001193522	FAM65A	family with sequence similarity 65, member A
chr1_+_28585959	1.185	NM_031459	SESN2	sestrin 2
chr4_-_82393025	1.184	NM_152545	RASGEF1B	RasGEF domain family, member 1B
chr22_+_50946627	1.183	NM_001185011 NM_014551 NM_152299	NCAPH2	non-SMC condensin II complex, subunit H2
chr19_-_18632857	1.181		ELL	elongation factor RNA polymerase II
chr2_-_27718059	1.181		FNDC4	fibronectin type III domain containing 4
chr19_-_51893791	1.181	NM_001193623	LOC147646	uncharacterized LOC147646
chr4_-_967327	1.181	NM_001347	DGKQ	diacylglycerol kinase, theta 110kDa
chr5_+_177540465	1.173	NM_015111	N4BP3	NEDD4 binding protein 3
chr16_+_2039945	1.173	NM_004209	SYNGR3	synaptogyrin 3
chr2_+_30369749	1.168	NM_001127399 NM_001127400 NM_001127401 NM_016061	YPEL5	yippee-like 5 (Drosophila)
chr16_+_66638652	1.167		CMTM3	CKLF-like MARVEL transmembrane domain containing 3
chr12_-_112819755	1.166	NM_001109662	C12orf51	chromosome 12 open reading frame 51
chr19_+_4969126	1.160		KDM4B	lysine (K)-specific demethylase 4B
chr7_-_45128492	1.158	NM_001146334	NACAD	NAC alpha domain containing
chr16_-_75285383	1.158	NM_001170717 NM_014567	BCAR1	breast cancer anti-estrogen resistance 1

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
2.16	4.47e-09	GO:0031323	regulation of cellular metabolic process
2.16	6.75e-09	GO:0080090	regulation of primary metabolic process
1.66	1.57e-08	GO:0050794	regulation of cellular process
2.15	4.20e-08	GO:0060255	regulation of macromolecule metabolic process
2.01	7.15e-08	GO:0019222	regulation of metabolic process
1.59	1.48e-07	GO:0050789	regulation of biological process
1.50	5.88e-06	GO:0065007	biological regulation
2.10	3.11e-05	GO:0009889	regulation of biosynthetic process
2.23	3.48e-05	GO:0051252	regulation of RNA metabolic process
2.09	5.57e-05	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.09	5.57e-05	GO:0031326	regulation of cellular biosynthetic process
2.62	7.38e-05	GO:0009966	regulation of signal transduction
2.47	9.20e-05	GO:0023051	regulation of signaling
2.02	1.52e-04	GO:0051171	regulation of nitrogen compound metabolic process
2.18	2.18e-04	GO:0006355	regulation of transcription, DNA-dependent
2.06	2.32e-04	GO:0010468	regulation of gene expression
2.08	2.35e-04	GO:0010556	regulation of macromolecule biosynthetic process
2.09	2.69e-04	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.82	9.11e-04	GO:0007165	signal transduction
2.20	1.29e-03	GO:0048583	regulation of response to stimulus
1.94	1.31e-03	GO:0048518	positive regulation of biological process
1.69	2.03e-03	GO:0051716	cellular response to stimulus
3.19	2.64e-03	GO:0042325	regulation of phosphorylation
3.23	3.76e-03	GO:0001932	regulation of protein phosphorylation
3.10	4.15e-03	GO:0019220	regulation of phosphate metabolic process
3.10	4.15e-03	GO:0051174	regulation of phosphorus metabolic process
1.71	5.20e-03	GO:0023052	signaling
2.01	6.33e-03	GO:0048523	negative regulation of cellular process
3.52	6.74e-03	GO:0043549	regulation of kinase activity
7.94	6.85e-03	GO:0046328	regulation of JNK cascade
3.87	7.78e-03	GO:0010627	regulation of intracellular protein kinase cascade
2.83	1.02e-02	GO:0031399	regulation of protein modification process
3.40	1.07e-02	GO:0051338	regulation of transferase activity
7.39	1.17e-02	GO:0070302	regulation of stress-activated protein kinase signaling cascade
3.46	1.60e-02	GO:0045859	regulation of protein kinase activity
3.62	1.73e-02	GO:0007243	intracellular protein kinase cascade
3.62	1.73e-02	GO:0023014	signal transduction via phosphorylation event
6.90	1.93e-02	GO:0031098	stress-activated protein kinase signaling cascade
10.07	2.51e-02	GO:0043506	regulation of JUN kinase activity
21.72	2.56e-02	GO:0048008	platelet-derived growth factor receptor signaling pathway
1.88	2.62e-02	GO:0048519	negative regulation of biological process
1.86	2.66e-02	GO:0048522	positive regulation of cellular process
4.20	2.88e-02	GO:0071900	regulation of protein serine/threonine kinase activity
5.51	3.61e-02	GO:0080135	regulation of cellular response to stress
4.38	4.22e-02	GO:0000165	MAPKKK cascade
2.20	4.50e-02	GO:0035556	intracellular signal transduction

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.49	2.27e-03	GO:0005634	nucleus

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
2.79	1.82e-04	GO:0001071	nucleic acid binding transcription factor activity
2.79	1.82e-04	GO:0003700	sequence-specific DNA binding transcription factor activity
2.04	1.82e-04	GO:0003677	DNA binding
1.43	5.02e-04	GO:0005515	protein binding
4.78	1.88e-03	GO:0019900	kinase binding
19.43	9.71e-03	GO:0004709	MAP kinase kinase kinase activity
18.46	1.20e-02	GO:0043621	protein self-association
4.67	1.31e-02	GO:0019901	protein kinase binding
1.19	1.90e-02	GO:0005488	binding
3.70	2.33e-02	GO:0016564	transcription repressor activity
92.28	2.48e-02	GO:0046592	polyamine oxidase activity
10.26	2.60e-02	GO:0046332	SMAD binding
9.42	3.91e-02	GO:0004702	receptor signaling protein serine/threonine kinase activity
25.17	4.13e-02	GO:0070411	I-SMAD binding