Motif ID: TFAP2B.p2

Z-value: 1.569


Transcription factors associated with TFAP2B.p2:

Gene SymbolEntrez IDGene Name
TFAP2B 7021 transcription factor AP-2 beta (activating enhancer binding protein 2 beta)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TFAP2Bhg19_v1_chr6_+_50786438_50786632-0.843.4e-02Click!


Activity profile for motif TFAP2B.p2.

activity profile for motif TFAP2B.p2


Sorted Z-values histogram for motif TFAP2B.p2

Sorted Z-values for motif TFAP2B.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TFAP2B.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_34972866 0.792 NM_001080436
WTIP
Wilms tumor 1 interacting protein
chr20_+_33814538 0.678 NM_006690
MMP24
matrix metallopeptidase 24 (membrane-inserted)
chr11_-_67141008 0.668 NM_013246
CLCF1
cardiotrophin-like cytokine factor 1
chr9_-_130679210 0.570 NM_175039
NM_175040
ST6GALNAC4

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4

chr19_+_47778099 0.568 NM_178511
PRR24
proline rich 24
chr9_-_86432546 0.567 NM_001135953
NM_025211
GKAP1

G kinase anchoring protein 1

chr9_+_138371627 0.560 NM_014811
PPP1R26
protein phosphatase 1, regulatory subunit 26
chr8_-_144512601 0.537 NM_201589
MAFA
v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
chr7_+_1570321 0.523 NM_002360
MAFK
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
chr1_+_87797301 0.474


chr8_+_32405727 0.448 NM_001160002
NM_001160004
NM_001160005
NM_001160007
NM_001160008
NM_004495
NM_013956
NM_013957
NM_013958
NM_013960
NM_013964
NRG1










neuregulin 1










chr21_+_38379070 0.439


chr2_+_241507928 0.438 NM_018226
RNPEPL1
arginyl aminopeptidase (aminopeptidase B)-like 1
chr17_-_76921076 0.434 TIMP2
TIMP metallopeptidase inhibitor 2
chr5_+_167956545 0.424


chr15_+_76352323 0.423 C15orf27
chromosome 15 open reading frame 27
chr19_+_6531009 0.414 NM_003811
TNFSF9
tumor necrosis factor (ligand) superfamily, member 9
chr1_-_33366838 0.412 NM_033504
TMEM54
transmembrane protein 54
chr9_-_38424422 0.398 NM_001007563
IGFBPL1
insulin-like growth factor binding protein-like 1
chr16_-_85784628 0.397 NM_206967
C16orf74
chromosome 16 open reading frame 74
chr6_+_139013551 0.396 FLJ46906
uncharacterized LOC441172
chr1_+_995109 0.396 LOC100288175
uncharacterized LOC100288175
chr19_+_663381 0.389


chr6_+_41606193 0.382 NM_005586
MDFI
MyoD family inhibitor
chr10_-_14879967 0.381 NM_001029954
CDNF
cerebral dopamine neurotrophic factor
chr2_+_241508103 0.379 RNPEPL1
arginyl aminopeptidase (aminopeptidase B)-like 1
chr16_+_50582193 0.377 NM_033119
NKD1
naked cuticle homolog 1 (Drosophila)
chr19_-_1863546 0.377 NM_031918
KLF16
Kruppel-like factor 16
chr19_-_46295647 0.364 DMWD
dystrophia myotonica, WD repeat containing
chr22_+_23412364 0.353 NM_002073
GNAZ
guanine nucleotide binding protein (G protein), alpha z polypeptide
chr17_-_48207113 0.351 NM_174920
SAMD14
sterile alpha motif domain containing 14
chr3_+_52280185 0.349 NM_001122870
PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr3_+_72937168 0.347 NM_001080393
GXYLT2
glucoside xylosyltransferase 2
chr11_-_47615902 0.343 NM_031909
C1QTNF4
C1q and tumor necrosis factor related protein 4
chrX_+_152953751 0.337 NM_001142805
NM_005629
SLC6A8

solute carrier family 6 (neurotransmitter transporter, creatine), member 8

chr19_+_13105970 0.337 NM_002501
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr3_+_159943628 0.334 C3orf80
chromosome 3 open reading frame 80
chr7_-_152132924 0.329 MLL3
myeloid/lymphoid or mixed-lineage leukemia 3
chr22_-_39190103 0.321 DNAL4
dynein, axonemal, light chain 4
chr7_-_149157866 0.320 NM_015694
ZNF777
zinc finger protein 777
chr16_-_3930120 0.319 NM_001079846
NM_004380
CREBBP

CREB binding protein

chr8_+_17013799 0.317 NM_016353
ZDHHC2
zinc finger, DHHC-type containing 2
chr6_+_36098261 0.317 NM_002754
MAPK13
mitogen-activated protein kinase 13
chr19_+_55987698 0.312 NM_033113
ZNF628
zinc finger protein 628
chr4_+_75480628 0.310 NM_001657
AREG
amphiregulin
chr1_-_40254131 0.308 BMP8B
bone morphogenetic protein 8b
chr19_+_42817434 0.308 NM_173633
TMEM145
transmembrane protein 145
chrX_+_153237990 0.305 NM_003492
TMEM187
transmembrane protein 187
chr8_+_17014006 0.302 ZDHHC2
zinc finger, DHHC-type containing 2
chr5_+_76114881 0.300 F2RL1
coagulation factor II (thrombin) receptor-like 1
chr8_+_17013459 0.300 ZDHHC2
zinc finger, DHHC-type containing 2
chr16_-_71757650 0.299 PHLPP2
PH domain and leucine rich repeat protein phosphatase 2
chr16_+_29817426 0.296 MAZ
MYC-associated zinc finger protein (purine-binding transcription factor)
chr12_+_93964801 0.295 SOCS2
suppressor of cytokine signaling 2
chr3_-_47620186 0.294 NM_001206943
NM_001206944
NM_006574
CSPG5


chondroitin sulfate proteoglycan 5 (neuroglycan C)


chr1_+_205782430 0.292


chr21_-_46359685 0.291 C21orf67
chromosome 21 open reading frame 67
chr3_-_169482847 0.289 TERC
telomerase RNA component
chr19_-_1863425 0.288 KLF16
Kruppel-like factor 16
chr15_-_80215663 0.288 NM_001100880
NM_001199757
ST20

suppressor of tumorigenicity 20

chr7_-_152133071 0.286 NM_170606
MLL3
myeloid/lymphoid or mixed-lineage leukemia 3
chr11_-_1593149 0.283 NM_004420
DUSP8
dual specificity phosphatase 8
chr11_-_695402 0.283 NM_021008
DEAF1
deformed epidermal autoregulatory factor 1 (Drosophila)
chr10_+_99609994 0.283 NM_001010917
GOLGA7B
golgin A7 family, member B
chr17_+_43299277 0.283 NM_005892
FMNL1
formin-like 1
chr11_-_535532 0.281 NM_001130442
NM_005343
NM_176795
HRAS


v-Ha-ras Harvey rat sarcoma viral oncogene homolog


chr20_+_62371109 0.280 NM_020062
SLC2A4RG
SLC2A4 regulator
chr5_-_11904127 0.273 CTNND2
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr16_-_54962707 0.272 CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr3_+_150126705 0.271 NM_014779
TSC22D2
TSC22 domain family, member 2
chr19_+_33685489 0.271 NM_002333
LRP3
low density lipoprotein receptor-related protein 3
chr6_+_157099262 0.269 ARID1B
AT rich interactive domain 1B (SWI1-like)
chr7_+_73082157 0.268 NM_001077621
VPS37D
vacuolar protein sorting 37 homolog D (S. cerevisiae)
chr20_+_62371218 0.267 SLC2A4RG
SLC2A4 regulator
chr19_-_8675559 0.266 NM_030957
ADAMTS10
ADAM metallopeptidase with thrombospondin type 1 motif, 10
chr14_-_56046791 0.266 KTN1-AS1
KTN1 antisense RNA 1 (non-protein coding)
chr13_+_60971426 0.266 NM_001146070
TDRD3
tudor domain containing 3
chr8_+_82192717 0.265 NM_001444
FABP5
fatty acid binding protein 5 (psoriasis-associated)
chr15_+_85291802 0.264 NM_014630
ZNF592
zinc finger protein 592
chr19_-_14228362 0.262 NM_002730
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr19_-_46295785 0.260 NM_004943
DMWD
dystrophia myotonica, WD repeat containing
chr22_+_37956404 0.259 NM_152243
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr3_+_52279742 0.259 NM_144641
PPM1M
protein phosphatase, Mg2+/Mn2+ dependent, 1M
chr7_-_158380360 0.255 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr8_+_144816287 0.255 LOC100128338
uncharacterized LOC100128338
chr4_+_4861371 0.254 NM_002448
MSX1
msh homeobox 1
chr1_-_40254521 0.253 NM_001720
BMP8B
bone morphogenetic protein 8b
chr7_+_4722091 0.253 FOXK1
forkhead box K1
chr4_+_139936938 0.251 NM_012118
CCRN4L
CCR4 carbon catabolite repression 4-like (S. cerevisiae)
chr7_-_76256475 0.251 NM_012230
NM_152992
POMZP3

POM121 and ZP3 fusion

chr4_-_6911373 0.251


chr6_+_5085719 0.251 NM_001145115
PPP1R3G
protein phosphatase 1, regulatory subunit 3G
chrX_-_108868250 0.249 NM_012282
KCNE1L
KCNE1-like
chr13_-_21635629 0.249 LATS2
LATS, large tumor suppressor, homolog 2 (Drosophila)
chr1_+_32827797 0.249 NM_052841
TSSK3
testis-specific serine kinase 3
chr22_-_43583132 0.248 NM_015140
TTLL12
tubulin tyrosine ligase-like family, member 12
chr16_-_75299713 0.247 NM_001170720
NM_001170714
NM_001170718
BCAR1


breast cancer anti-estrogen resistance 1


chr7_+_18126543 0.244 NM_001204144
HDAC9
histone deacetylase 9
chr4_+_48492255 0.243 NM_175619
ZAR1
zygote arrest 1
chr1_-_33430285 0.242 NM_001127361
NM_153341
RNF19B

ring finger protein 19B

chr6_+_41514289 0.242 FOXP4
forkhead box P4
chrX_-_153602998 0.241 NM_001110556
NM_001456
FLNA

filamin A, alpha

chr6_+_157099041 0.240 NM_017519
NM_020732
ARID1B

AT rich interactive domain 1B (SWI1-like)

chr6_-_13711952 0.240 RANBP9
RAN binding protein 9
chr20_+_62371730 0.240 SLC2A4RG
SLC2A4 regulator
chr10_+_104404195 0.239 NM_030912
TRIM8
tripartite motif containing 8
chr2_+_223289285 0.238 NM_152386
SGPP2
sphingosine-1-phosphate phosphatase 2
chr12_+_49212253 0.238 NM_000725
NM_001206915
CACNB3

calcium channel, voltage-dependent, beta 3 subunit

chr19_-_17356022 0.237 NM_005234
NR2F6
nuclear receptor subfamily 2, group F, member 6
chr12_-_121342050 0.237 NM_139015
SPPL3
signal peptide peptidase-like 3
chr2_+_223536362 0.237 NM_058165
MOGAT1
monoacylglycerol O-acyltransferase 1
chr22_-_42322778 0.236 NM_052945
TNFRSF13C
tumor necrosis factor receptor superfamily, member 13C
chr9_-_138391696 0.234 NM_001048265
NM_144654
C9orf116

chromosome 9 open reading frame 116

chr20_-_3766905 0.234 NM_001810
CENPB
centromere protein B, 80kDa
chr6_+_108882068 0.234 NM_001455
FOXO3
forkhead box O3
chr5_+_139028483 0.233 CXXC5
CXXC finger protein 5
chr19_-_11616395 0.232 ZNF653
zinc finger protein 653
chr5_+_139027907 0.232 CXXC5
CXXC finger protein 5
chr6_+_19837599 0.231 NM_001546
ID4
inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
chr18_-_45457145 0.231 SMAD2
SMAD family member 2
chr7_-_32982574 0.230 RP9P
retinitis pigmentosa 9 pseudogene
chr2_+_132285469 0.230 NM_138770
CCDC74A
coiled-coil domain containing 74A
chr17_-_8066254 0.230 NM_014232
VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr19_+_7660698 0.230 NM_001080429
NM_020902
CAMSAP3

calmodulin regulated spectrin-associated protein family, member 3

chr6_-_26017960 0.229 NM_005325
HIST1H1A
histone cluster 1, H1a
chr15_+_76352270 0.227 NM_152335
C15orf27
chromosome 15 open reading frame 27
chr6_-_91006460 0.227 NM_021813
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr18_+_8609670 0.227


chr15_-_40212227 0.227


chr1_-_1284755 0.226 DVL1
dishevelled, dsh homolog 1 (Drosophila)
chr20_+_13202417 0.226 NM_080826
ISM1
isthmin 1 homolog (zebrafish)
chr19_+_1067114 0.226 NM_012292
HMHA1
histocompatibility (minor) HA-1
chr19_-_3028901 0.224 NM_003260
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr19_-_1237840 0.224 NM_152769
C19orf26
chromosome 19 open reading frame 26
chr2_+_39893021 0.224 NM_152390
TMEM178
transmembrane protein 178
chr8_-_48650683 0.224 CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr20_+_62371619 0.223 SLC2A4RG
SLC2A4 regulator
chr4_+_74735107 0.223 NM_001511
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr8_+_30241943 0.223 NM_001008710
NM_001008711
NM_001008712
NM_006867
RBPMS



RNA binding protein with multiple splicing



chrX_-_154114431 0.222 NM_019863
F8
coagulation factor VIII, procoagulant component
chr6_-_110679474 0.222 NM_001123364
C6orf186
chromosome 6 open reading frame 186
chr15_+_63796793 0.219 NM_006537
USP3
ubiquitin specific peptidase 3
chr20_+_2673193 0.219 NM_001110514
EBF4
early B-cell factor 4
chrX_-_17879355 0.217 NM_001172732
NM_001172739
NM_001172743
NM_021785
RAI2



retinoic acid induced 2



chr17_+_17584772 0.216 NM_030665
RAI1
retinoic acid induced 1
chr2_+_219824346 0.216 NM_003936
CDK5R2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr5_-_11903964 0.215 NM_001332
CTNND2
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr3_+_12329332 0.215 NM_005037
NM_138712
PPARG

peroxisome proliferator-activated receptor gamma

chr15_+_85291850 0.214 ZNF592
zinc finger protein 592
chr13_-_37494370 0.214 NM_001127217
NM_005905
SMAD9

SMAD family member 9

chr10_+_81002836 0.213 ZMIZ1
zinc finger, MIZ-type containing 1
chr19_-_58858900 0.213 A1BG
alpha-1-B glycoprotein
chr12_+_3068442 0.213 NM_003213
NM_201441
NM_201443
TEAD4


TEA domain family member 4


chr1_-_150947202 0.213 CERS2
ceramide synthase 2
chr19_+_589849 0.213 NM_001194
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr12_-_105501410 0.212 LOC414300
uncharacterized LOC414300
chr2_-_110970103 0.212 LINC00116
long intergenic non-protein coding RNA 116
chr20_-_62130390 0.212 NM_001958
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr7_+_48128738 0.210 NM_003364
UPP1
uridine phosphorylase 1
chr16_-_88772732 0.210 NM_001171815
RNF166
ring finger protein 166
chr19_-_4065467 0.209 ZBTB7A
zinc finger and BTB domain containing 7A
chr19_+_10982369 0.209 CARM1
coactivator-associated arginine methyltransferase 1
chr19_-_16738986 0.209 NM_004831
MED26
mediator complex subunit 26
chr1_+_223900328 0.209 CAPN2
calpain 2, (m/II) large subunit
chr16_-_58231641 0.208 NM_001896
CSNK2A2
casein kinase 2, alpha prime polypeptide
chr1_+_226271314 0.207


chr1_+_212782103 0.207 ATF3
activating transcription factor 3
chr9_+_133710746 0.206 NM_005157
ABL1
c-abl oncogene 1, non-receptor tyrosine kinase
chr19_+_3224734 0.206 CELF5
CUGBP, Elav-like family member 5
chr16_-_75285383 0.206 NM_001170717
NM_014567
BCAR1

breast cancer anti-estrogen resistance 1

chr19_+_1067293 0.206 HMHA1
histocompatibility (minor) HA-1
chr9_+_114659439 0.205 UGCG
UDP-glucose ceramide glucosyltransferase
chr6_+_157099203 0.204


chr4_-_1242742 0.204 CTBP1
C-terminal binding protein 1
chr19_+_4007690 0.204 NM_015897
PIAS4
protein inhibitor of activated STAT, 4
chr8_+_56686179 0.203


chr10_+_119000583 0.203 NM_003054
SLC18A2
solute carrier family 18 (vesicular monoamine), member 2
chr1_-_150947127 0.202 CERS2
ceramide synthase 2
chr6_-_168720389 0.201 NM_214462
DACT2
dapper, antagonist of beta-catenin, homolog 2 (Xenopus laevis)
chr12_-_1703330 0.201 NM_152441
FBXL14
F-box and leucine-rich repeat protein 14
chr22_-_46933066 0.201 NM_014246
CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr2_-_39348127 0.201 SOS1
son of sevenless homolog 1 (Drosophila)
chr9_-_34522972 0.201 NM_198573
ENHO
energy homeostasis associated
chr2_-_106015423 0.199 NM_001039492
NM_001450
NM_201555
FHL2


four and a half LIM domains 2


chr19_+_45504686 0.199 NM_006509
RELB
v-rel reticuloendotheliosis viral oncogene homolog B
chr22_+_50354139 0.198 NM_001001852
PIM3
pim-3 oncogene
chr5_+_69696805 0.198 SMA4
glucuronidase, beta pseudogene
chr17_+_15848230 0.198 NM_000676
ADORA2B
adenosine A2b receptor
chr19_+_1067536 0.198 HMHA1
histocompatibility (minor) HA-1
chr20_-_62680880 0.198 NM_018419
SOX18
SRY (sex determining region Y)-box 18
chr18_+_56530677 0.197 ZNF532
zinc finger protein 532
chr15_+_63796773 0.196 USP3
ubiquitin specific peptidase 3
chr6_+_41514133 0.196 NM_001012426
NM_001012427
NM_138457
FOXP4


forkhead box P4


chr14_-_24610741 0.195 NM_016049
FAM158A
family with sequence similarity 158, member A
chr19_-_913194 0.195 R3HDM4
R3H domain containing 4
chr12_+_129338051 0.195 NM_144669
GLT1D1
glycosyltransferase 1 domain containing 1
chr22_-_20792107 0.195 NM_153334
NM_182895
SCARF2

scavenger receptor class F, member 2

chr1_-_150947305 0.194 CERS2
ceramide synthase 2
chr15_-_38856830 0.194 NM_001128602
NM_005739
RASGRP1

RAS guanyl releasing protein 1 (calcium and DAG-regulated)

chr12_-_100378431 0.194 NM_152788
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.