Motif ID: CREB1.p2

Z-value: 0.933


Transcription factors associated with CREB1.p2:

Gene SymbolEntrez IDGene Name
CREB1 1385 cAMP responsive element binding protein 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
CREB1hg19_v1_chr2_+_208394756_2083948060.862.7e-02Click!


Activity profile for motif CREB1.p2.

activity profile for motif CREB1.p2


Sorted Z-values histogram for motif CREB1.p2

Sorted Z-values for motif CREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CREB1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_-_27410852 0.586 NM_199347
NEK10
NIMA (never in mitosis gene a)- related kinase 10
chr3_-_59035700 0.570 NM_198463
C3orf67
chromosome 3 open reading frame 67
chr4_-_120375770 0.545


chr16_+_19078916 0.530 NM_016138
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr6_+_35227300 0.503 ZNF76
zinc finger protein 76
chr1_+_206808751 0.489 NM_001004023
NM_003582
DYRK3

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3

chr6_+_26204779 0.482 NM_003545
HIST1H4E
histone cluster 1, H4e
chr6_+_35227234 0.462 ZNF76
zinc finger protein 76
chr3_-_10067989 0.462 CIDECP
cell death-inducing DFFA-like effector c pseudogene
chr19_+_54058493 0.443 NM_001079907
ZNF331
zinc finger protein 331
chr16_+_19078958 0.440 COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr3_+_127317274 0.425 MCM2
minichromosome maintenance complex component 2
chr3_+_127317271 0.409 MCM2
minichromosome maintenance complex component 2
chr4_+_75480628 0.398 NM_001657
AREG
amphiregulin
chr6_+_26217145 0.388 NM_021052
HIST1H2AE
histone cluster 1, H2ae
chr2_-_157189040 0.381 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr1_+_192778168 0.378 NM_002923
RGS2
regulator of G-protein signaling 2, 24kDa
chr4_+_668250 0.376 MYL5
myosin, light chain 5, regulatory
chr1_+_142618798 0.375


chrX_-_7895424 0.373 NM_004650
PNPLA4
patatin-like phospholipase domain containing 4
chr11_+_66610882 0.366 NM_001032279
NM_005133
RCE1

RCE1 homolog, prenyl protein protease (S. cerevisiae)

chr4_-_8442427 0.362 NM_001101667
NM_003501
ACOX3

acyl-CoA oxidase 3, pristanoyl

chr3_+_127317212 0.357 NM_004526
MCM2
minichromosome maintenance complex component 2
chr12_-_53448167 0.345 LOC283335
uncharacterized LOC283335
chr19_-_46088074 0.342 OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr6_+_170151711 0.337 NM_018341
C6orf70
chromosome 6 open reading frame 70
chr1_+_29562947 0.332 NM_001195001
NM_005704
NM_133177
NM_133178
PTPRU



protein tyrosine phosphatase, receptor type, U



chr8_+_42396716 0.332 NM_138436
NM_001135674
NM_001135675
C8orf40


chromosome 8 open reading frame 40


chr10_+_43932573 0.330 ZNF487P
zinc finger protein 487, pseudogene
chr6_-_170151627 0.329 NM_174910
TCTE3
t-complex-associated-testis-expressed 3
chr19_+_36103616 0.326 NM_015302
HAUS5
HAUS augmin-like complex, subunit 5
chr22_-_41252646 0.319 ST13
suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein)
chr9_-_127703230 0.318 GOLGA1
golgin A1
chr1_-_15850776 0.316 NM_001229
NM_032996
CASP9

caspase 9, apoptosis-related cysteine peptidase

chr12_+_2921786 0.313 NM_018463
ITFG2
integrin alpha FG-GAP repeat containing 2
chr16_+_19079220 0.307 NM_001190983
COQ7
coenzyme Q7 homolog, ubiquinone (yeast)
chr7_-_140624280 0.301 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr7_-_1199822 0.299 NM_182491
ZFAND2A
zinc finger, AN1-type domain 2A
chr9_-_127703294 0.298 NM_002077
GOLGA1
golgin A1
chrX_+_7065820 0.298 STS
steroid sulfatase (microsomal), isozyme S
chr11_-_28129646 0.298 KIF18A
kinesin family member 18A
chr20_+_33292117 0.297 NM_021202
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr3_-_190580464 0.296 NM_001146686
GMNC
geminin coiled-coil domain containing
chr13_+_45915479 0.292 LOC100190939
uncharacterized LOC100190939
chr6_-_38607589 0.291 BTBD9
BTB (POZ) domain containing 9
chr6_+_35227478 0.287 NM_003427
ZNF76
zinc finger protein 76
chr22_+_51021454 0.285 LOC100144603
uncharacterized transcript
chr7_+_98246595 0.282 NM_002523
NPTX2
neuronal pentraxin II
chr16_-_3930713 0.280 CREBBP
CREB binding protein
chr10_+_6186903 0.278 PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr1_+_36690038 0.278 THRAP3
thyroid hormone receptor associated protein 3
chr2_+_220071493 0.277 NM_138802
ZFAND2B
zinc finger, AN1-type domain 2B
chr6_+_27114860 0.274 NM_080596
HIST1H2AH
histone cluster 1, H2ah
chr9_-_125027080 0.266 NM_033117
RBM18
RNA binding motif protein 18
chr4_-_146019296 0.263 NM_014885
ANAPC10
anaphase promoting complex subunit 10
chr7_-_1199813 0.263 ZFAND2A
zinc finger, AN1-type domain 2A
chr10_+_6244839 0.262 NM_004566
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr17_-_15902907 0.261 NM_001042697
NM_001042698
ZSWIM7

zinc finger, SWIM-type containing 7

chr12_-_58165877 0.260 NM_005371
NM_023033
METTL1

methyltransferase like 1

chr8_-_82024277 0.260 NM_018440
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr9_-_134955243 0.258 NM_004269
CRSP8P
MED27
mediator complex subunit 27 pseudogene
mediator complex subunit 27
chr10_-_93392799 0.258 PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr20_+_5891973 0.255 NM_001819
CHGB
chromogranin B (secretogranin 1)
chr4_+_8442496 0.255 NM_152544
METTL19
methyltransferase like 19
chr16_-_3930685 0.252 CREBBP
CREB binding protein
chr15_-_72612247 0.251 NM_001172684
CELF6
CUGBP, Elav-like family member 6
chr3_+_16306666 0.250 NM_138381
OXNAD1
oxidoreductase NAD-binding domain containing 1
chr9_-_139981102 0.250 LOC100289341
uncharacterized LOC100289341
chr7_-_1199785 0.248 ZFAND2A
zinc finger, AN1-type domain 2A
chr5_-_107717798 0.246 NM_001163315
FBXL17
F-box and leucine-rich repeat protein 17
chr7_-_45026204 0.243 SNHG15
small nucleolar RNA host gene 15 (non-protein coding)
chr3_+_128598471 0.240 ACAD9
acyl-CoA dehydrogenase family, member 9
chr3_+_10068139 0.239 FANCD2
Fanconi anemia, complementation group D2
chr22_+_18893735 0.238 NM_005675
DGCR6
DiGeorge syndrome critical region gene 6
chr10_+_6186758 0.237 NM_001145443
PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr6_-_28303910 0.236 NM_001135216
NM_001243243
ZNF323

zinc finger protein 323

chr11_-_116968986 0.230 NM_025164
SIK3
SIK family kinase 3
chr16_+_2802708 0.230 SRRM2
serine/arginine repetitive matrix 2
chr19_-_2702662 0.229 GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr4_-_113558021 0.225 C4orf21
chromosome 4 open reading frame 21
chr11_+_117049387 0.225 SIDT2
SID1 transmembrane family, member 2
chr6_+_35310317 0.224 NM_001171818
NM_001171819
NM_001171820
NM_006238
NM_177435
PPARD




peroxisome proliferator-activated receptor delta




chr3_+_156544075 0.224 NM_001004316
NM_001193283
LEKR1

leucine, glutamate and lysine rich 1

chr17_-_37844266 0.221 NM_033419
PGAP3
post-GPI attachment to proteins 3
chr1_-_211751719 0.218 SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr10_+_6186878 0.218 PFKFB3
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr8_+_37594155 0.218 ERLIN2
ER lipid raft associated 2
chr19_+_16435734 0.217 KLF2
Kruppel-like factor 2 (lung)
chr5_+_157170702 0.217 NM_173491
LSM11
LSM11, U7 small nuclear RNA associated
chrX_+_152224862 0.216 PNMA3
paraneoplastic antigen MA3
chr1_+_180199432 0.214 NM_033343
LHX4
LIM homeobox 4
chr13_+_51483912 0.211 RNASEH2B
ribonuclease H2, subunit B
chr6_+_30524485 0.211 NM_001077497
NM_025263
PRR3

proline rich 3

chr12_+_7282963 0.209 NM_014718
CLSTN3
calsyntenin 3
chr12_-_10766130 0.206 NM_018048
MAGOHB
mago-nashi homolog B (Drosophila)
chr16_+_88772884 0.206 NM_001012759
NM_001012762
CTU2

cytosolic thiouridylase subunit 2 homolog (S. pombe)

chr2_-_25194772 0.205 NM_001198559
NM_016544
DNAJC27

DnaJ (Hsp40) homolog, subfamily C, member 27

chr10_+_114709963 0.203 NM_001146274
NM_001146283
NM_001146284
NM_001146285
NM_001146286
NM_001198525
NM_001198526
NM_001198527
NM_001198528
NM_001198529
NM_001198530
NM_001198531
NM_030756
TCF7L2












transcription factor 7-like 2 (T-cell specific, HMG-box)












chr17_+_4046941 0.202 CYB5D2
cytochrome b5 domain containing 2
chr1_+_150980895 0.202 NM_021222
PRUNE
prune homolog (Drosophila)
chr17_-_76836852 0.201 NM_025090
USP36
ubiquitin specific peptidase 36
chr9_-_99775855 0.198 HIATL2
hippocampus abundant transcript-like 2
chr4_-_8430185 0.198 ACOX3
acyl-CoA oxidase 3, pristanoyl
chr11_+_64052282 0.197 NM_001177358
NM_001170881
GPR137

G protein-coupled receptor 137

chr13_+_51483901 0.196 RNASEH2B
ribonuclease H2, subunit B
chr3_+_128598332 0.196 NM_014049
ACAD9
acyl-CoA dehydrogenase family, member 9
chr1_+_36689996 0.195 NM_005119
THRAP3
thyroid hormone receptor associated protein 3
chr3_+_93698959 0.194 NM_001174150
NM_001174151
NM_144996
NM_182896
ARL13B



ADP-ribosylation factor-like 13B



chr9_-_111696322 0.193 IKBKAP
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
chr4_-_113558120 0.193 NM_018392
C4orf21
chromosome 4 open reading frame 21
chr17_-_35293920 0.193


chr6_-_31671054 0.192 ABHD16A
abhydrolase domain containing 16A
chr3_+_128598459 0.192 ACAD9
acyl-CoA dehydrogenase family, member 9
chr6_-_38607635 0.192 BTBD9
BTB (POZ) domain containing 9
chr4_+_119199906 0.191 SNHG8
small nucleolar RNA host gene 8 (non-protein coding)
chr9_-_111696173 0.191 IKBKAP
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
chr10_+_38645293 0.190 HSD17B7P2
hydroxysteroid (17-beta) dehydrogenase 7 pseudogene 2
chr16_-_4588738 0.189 NM_001199055
NM_001199056
NM_013399
C16orf5


chromosome 16 open reading frame 5


chr4_+_108911042 0.189 HADH
hydroxyacyl-CoA dehydrogenase
chr7_+_100209724 0.187 NM_001040097
MOSPD3
motile sperm domain containing 3
chr8_-_17104266 0.187 NM_013354
NM_054026
CNOT7

CCR4-NOT transcription complex, subunit 7

chr11_+_117070039 0.187 NM_001001522
NM_003186
TAGLN

transgelin

chr2_+_220071948 0.186 ZFAND2B
zinc finger, AN1-type domain 2B
chr7_-_73184535 0.185 NM_001306
CLDN3
claudin 3
chr18_+_2571509 0.183 NM_006101
NDC80
NDC80 kinetochore complex component homolog (S. cerevisiae)
chr16_-_88772732 0.183 NM_001171815
RNF166
ring finger protein 166
chr11_-_28129701 0.183 NM_031217
KIF18A
kinesin family member 18A
chr3_-_9291251 0.183 NM_001033117
NM_014850
SRGAP3

SLIT-ROBO Rho GTPase activating protein 3

chr15_+_75287829 0.183 NM_001178111
NM_001178112
NM_138967
SCAMP5


secretory carrier membrane protein 5


chr1_+_9648931 0.182 NM_001010866
NM_001130924
TMEM201

transmembrane protein 201

chr7_+_55433396 0.182 LANCL2
LanC lantibiotic synthetase component C-like 2 (bacterial)
chr4_-_111544206 0.181 NM_000325
PITX2
paired-like homeodomain 2
chr9_-_139981268 0.181 LOC100289341
uncharacterized LOC100289341
chr10_-_118032975 0.181 NM_005264
GFRA1
GDNF family receptor alpha 1
chr6_+_35310368 0.180 PPARD
peroxisome proliferator-activated receptor delta
chr1_+_206809048 0.179 DYRK3
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
chr4_+_108911008 0.179 HADH
hydroxyacyl-CoA dehydrogenase
chr17_-_76836718 0.178 USP36
ubiquitin specific peptidase 36
chr4_+_153457407 0.177 DKFZP434I0714
uncharacterized protein DKFZP434I0714
chr10_-_93392857 0.177 NM_005398
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr8_+_41386724 0.175 NM_032336
GINS4
GINS complex subunit 4 (Sld5 homolog)
chr9_-_140024159 0.175


chr17_+_7387688 0.175 NM_000937
POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr1_+_228645807 0.174 NM_175055
HIST3H2BB
histone cluster 3, H2bb
chrX_-_7895764 0.174 NM_001142389
NM_001172672
PNPLA4

patatin-like phospholipase domain containing 4

chr16_-_3767449 0.173 NM_016292
TRAP1
TNF receptor-associated protein 1
chr19_-_46088021 0.172 OPA3
optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
chr18_-_658246 0.172 NM_001012716
C18orf56
chromosome 18 open reading frame 56
chr4_+_108910869 0.172 NM_001184705
NM_005327
HADH

hydroxyacyl-CoA dehydrogenase

chr16_+_25123041 0.171 NM_001032391
NM_016309
LCMT1

leucine carboxyl methyltransferase 1

chr17_-_685385 0.170 NM_016080
GLOD4
glyoxalase domain containing 4
chr20_-_5100443 0.170 NM_182649
PCNA
proliferating cell nuclear antigen
chr2_+_109403140 0.170 NM_144978
CCDC138
coiled-coil domain containing 138
chrX_+_152224765 0.170 NM_013364
PNMA3
paraneoplastic antigen MA3
chr20_+_44563310 0.169 NM_022104
PCIF1
PDX1 C-terminal inhibiting factor 1
chr6_+_126277847 0.169 NM_138571
HINT3
histidine triad nucleotide binding protein 3
chr1_-_713985 0.167 LOC100288069
general transcription factor IIi pseudogene
chr17_+_7387773 0.166 POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr11_+_4116077 0.166 RRM1
ribonucleotide reductase M1
chr16_+_2802605 0.166 SRRM2
serine/arginine repetitive matrix 2
chr16_+_2802640 0.165 SRRM2
serine/arginine repetitive matrix 2
chr3_+_128598440 0.165 ACAD9
acyl-CoA dehydrogenase family, member 9
chr3_-_37034567 0.165


chr6_+_35310399 0.165 PPARD
peroxisome proliferator-activated receptor delta
chrX_-_44202834 0.164 NM_025184
EFHC2
EF-hand domain (C-terminal) containing 2
chr6_-_170151553 0.164 TCTE3
t-complex-associated-testis-expressed 3
chr6_-_31671120 0.164 NM_021160
ABHD16A
abhydrolase domain containing 16A
chr11_+_73019662 0.164 NM_014786
ARHGEF17
Rho guanine nucleotide exchange factor (GEF) 17
chr4_-_104119475 0.161 NM_001813
CENPE
centromere protein E, 312kDa
chr7_-_65235688 0.161 LOC441242
uncharacterized LOC441242
chr1_+_12040504 0.160 MFN2
mitofusin 2
chr16_+_25123096 0.160 LCMT1
leucine carboxyl methyltransferase 1
chr16_+_30007562 0.160 INO80E
INO80 complex subunit E
chr19_+_45349560 0.159 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr20_+_23342786 0.158 GZF1
GDNF-inducible zinc finger protein 1
chr17_-_42264075 0.158 NM_178542
C17orf65
chromosome 17 open reading frame 65
chr1_-_15850692 0.157 CASP9
caspase 9, apoptosis-related cysteine peptidase
chr1_-_117664349 0.157 NM_001145635
NM_025188
TRIM45

tripartite motif containing 45

chr11_+_73087396 0.156 NM_152222
RELT
RELT tumor necrosis factor receptor
chr20_-_5107185 0.156 NM_002592
PCNA
proliferating cell nuclear antigen
chr1_-_40105296 0.156 HEYL
hairy/enhancer-of-split related with YRPW motif-like
chr12_+_58138663 0.156 NM_005981
TSPAN31
tetraspanin 31
chr16_+_2802652 0.156 SRRM2
serine/arginine repetitive matrix 2
chr18_+_72922725 0.156 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr1_+_32671235 0.155 NM_001160042
NM_018134
IQCC

IQ motif containing C

chr17_-_42264023 0.154 C17orf65
chromosome 17 open reading frame 65
chr16_-_66959418 0.154 NM_001128850
NM_004165
RRAD

Ras-related associated with diabetes

chrX_-_15353634 0.154 PIGA
phosphatidylinositol glycan anchor biosynthesis, class A
chr8_+_37594182 0.154 NM_001003790
ERLIN2
ER lipid raft associated 2
chr11_+_111473099 0.153 NM_015191
SIK2
salt-inducible kinase 2
chr16_+_28722781 0.153 NM_001099661
NM_001037808
NM_003752
EIF3CL
EIF3C

eukaryotic translation initiation factor 3, subunit C-like
eukaryotic translation initiation factor 3, subunit C

chr11_-_28129687 0.153 KIF18A
kinesin family member 18A
chr11_-_6633400 0.153 TAF10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr17_-_8059637 0.151 PER1
period homolog 1 (Drosophila)
chr12_-_57824787 0.151 R3HDM2
R3H domain containing 2
chr15_+_62682682 0.150 TLN2
talin 2
chr1_+_12040475 0.150 MFN2
mitofusin 2
chr6_-_31671089 0.149 ABHD16A
abhydrolase domain containing 16A
chr5_-_137090049 0.149


chr12_+_51632654 0.148 DAZAP2
DAZ associated protein 2

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.