• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: E2F1..5.p2

Z-value: 4.530

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr6_+_27833033	4.931	NM_003511	HIST1H2AI HIST1H2AL	histone cluster 1, H2ai histone cluster 1, H2al
chr22_-_38966066	3.905	NM_007068	DMC1	DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)
chr1_-_23857711	3.878	NM_004091	E2F2	E2F transcription factor 2
chr6_+_26045611	3.869	NM_003531	HIST1H3C	histone cluster 1, H3c
chr1_-_23857284	3.660		E2F2	E2F transcription factor 2
chr22_+_35796104	3.569	NM_006739	MCM5	minichromosome maintenance complex component 5
chr22_+_35796154	3.448		MCM5	minichromosome maintenance complex component 5
chr19_+_4909447	3.308	NM_001048201	UHRF1	ubiquitin-like with PHD and ring finger domains 1
chr6_+_27775898	3.163	NM_003509	HIST1H2AI HIST1H2AM HIST1H3F	histone cluster 1, H2ai histone cluster 1, H2am histone cluster 1, H3f
chr20_-_5100443	2.939	NM_182649	PCNA	proliferating cell nuclear antigen
chr7_+_113726490	2.888		FOXP2	forkhead box P2
chr6_-_27775683	2.884	NM_003519	HIST1H2BL	histone cluster 1, H2bl
chr6_+_27114860	2.728	NM_080596	HIST1H2AH	histone cluster 1, H2ah
chr4_-_146859960	2.656
chr2_-_136633934	2.644		MCM6	minichromosome maintenance complex component 6
chr22_+_35796294	2.611		MCM5	minichromosome maintenance complex component 5
chr11_-_19263144	2.588		E2F8	E2F transcription factor 8
chr2_+_16080639	2.510	NM_005378	MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr19_+_4910166	2.410		UHRF1	ubiquitin-like with PHD and ring finger domains 1
chr2_-_136634002	2.388	NM_005915	MCM6	minichromosome maintenance complex component 6
chr20_-_32274070	2.356		E2F1	E2F transcription factor 1
chr20_-_32274154	2.333	NM_005225	E2F1	E2F transcription factor 1
chr20_-_44563573	2.321		FLJ40606	uncharacterized LOC643549
chr16_+_72698996	2.293
chr7_-_95225802	2.279	NM_002612	PDK4	pyruvate dehydrogenase kinase, isozyme 4
chr15_+_66994669	2.254	NM_005585	SMAD6	SMAD family member 6
chr11_-_19262424	2.253	NM_024680	E2F8	E2F transcription factor 8
chr7_+_94285736	2.133		PEG10	paternally expressed 10
chr6_+_26021906	2.116	NM_003538	HIST1H4A	histone cluster 1, H4a
chrX_-_131623994	2.063	NM_001170704	MBNL3	muscleblind-like 3 (Drosophila)
chr7_+_94285676	2.032	NM_001172437 NM_001172438	PEG10	paternally expressed 10
chr7_+_94285620	2.030	NM_001040152 NM_001184961 NM_001184962 NM_015068	PEG10	paternally expressed 10
chr2_+_16080559	1.913		MYCN	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr20_-_35724330	1.818		RBL1	retinoblastoma-like 1 (p107)
chr3_+_127317274	1.806		MCM2	minichromosome maintenance complex component 2
chr12_-_77459198	1.796	NM_203394	E2F7	E2F transcription factor 7
chr3_+_127317271	1.793		MCM2	minichromosome maintenance complex component 2
chr3_+_127317212	1.755	NM_004526	MCM2	minichromosome maintenance complex component 2
chr20_-_35724401	1.706	NM_002895 NM_183404	RBL1	retinoblastoma-like 1 (p107)
chr11_-_694842	1.697		DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)
chr15_+_66995414	1.681		SMAD6	SMAD family member 6
chr3_-_123167391	1.674	NM_183357	ADCY5	adenylate cyclase 5
chr6_-_52149472	1.639		MCM3	minichromosome maintenance complex component 3
chr6_+_27861202	1.635	NM_003527	HIST1H2BO	histone cluster 1, H2bo
chr6_-_52149516	1.592		MCM3	minichromosome maintenance complex component 3
chr12_-_133263988	1.589		POLE	polymerase (DNA directed), epsilon
chr8_+_121457642	1.578	NM_022045	MTBP	Mdm2, transformed 3T3 cell double minute 2, p53 binding protein (mouse) binding protein, 104kDa
chr15_-_64673569	1.573	NM_001029989 NM_014736	KIAA0101	KIAA0101
chr7_+_129074235	1.546	NM_001134336 NM_020704	FAM40B	family with sequence similarity 40, member B
chr6_-_52149541	1.536	NM_002388	MCM3	minichromosome maintenance complex component 3
chr5_+_36152221	1.482		SKP2	S-phase kinase-associated protein 2 (p45)
chr7_+_113726364	1.481		FOXP2	forkhead box P2
chr6_-_27840086	1.475	NM_003533	HIST1H3I	histone cluster 1, H3i
chr16_+_67596309	1.458	NM_001191022 NM_006565	CTCF	CCCTC-binding factor (zinc finger protein)
chr6_+_35181721	1.441		SCUBE3	signal peptide, CUB domain, EGF-like 3
chr6_-_153304093	1.426	NM_012177	FBXO5	F-box protein 5
chr8_+_48873446	1.369		MCM4	minichromosome maintenance complex component 4
chr1_+_2518071	1.361	NM_001195736 NM_001195737 NM_001195738 NM_001195740 NM_001195741 NM_152371	FAM213B	family with sequence similarity 213, member B
chr15_+_80987609	1.353	NM_021214	FAM108C1	family with sequence similarity 108, member C1
chr12_-_98897622	1.351		LOC643770	uncharacterized LOC643770
chr5_+_36152142	1.344	NM_001243120 NM_005983 NM_032637	SKP2	S-phase kinase-associated protein 2 (p45)
chr17_+_38444130	1.332		CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr8_+_48873533	1.328		MCM4	minichromosome maintenance complex component 4
chr19_-_10305600	1.327		DNMT1	DNA (cytosine-5-)-methyltransferase 1
chr10_+_13203547	1.313	NM_018518 NM_182751	MCM10	minichromosome maintenance complex component 10
chr9_-_99180539	1.311		ZNF367	zinc finger protein 367
chr9_-_99180661	1.311	NM_153695	ZNF367	zinc finger protein 367
chr12_+_109535922	1.310	NM_003362	UNG	uracil-DNA glycosylase
chr11_+_65029312	1.310	NM_002689	POLA2	polymerase (DNA directed), alpha 2 (70kD subunit)
chr19_+_4910339	1.302	NM_013282	UHRF1	ubiquitin-like with PHD and ring finger domains 1
chr6_-_41863086	1.301	NM_018561	USP49	ubiquitin specific peptidase 49
chr17_+_56065408	1.297
chr2_+_10262853	1.284	NM_001034	RRM2	ribonucleotide reductase M2
chr7_+_99699129	1.268	NM_004722	AP4M1	adaptor-related protein complex 4, mu 1 subunit
chr10_+_73723992	1.264	NM_004273	CHST3	carbohydrate (chondroitin 6) sulfotransferase 3
chr1_-_36235422	1.256	NM_001190481 NM_022111	CLSPN	claspin
chr6_+_27100784	1.253	NM_021064	HIST1H2AG	histone cluster 1, H2ag
chr12_+_109535377	1.253	NM_080911	UNG	uracil-DNA glycosylase
chr1_+_228645807	1.243	NM_175055	HIST3H2BB	histone cluster 3, H2bb
chr19_+_50094911	1.231	NM_020719	PRR12	proline rich 12
chr16_+_84150634	1.229		LOC729887	uncharacterized LOC729887
chr11_-_695010	1.225		DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)
chr14_+_105941061	1.209	NM_001312	CRIP2	cysteine-rich protein 2
chr16_-_3930120	1.199	NM_001079846 NM_004380	CREBBP	CREB binding protein
chr7_+_113726592	1.186		FOXP2	forkhead box P2
chr17_+_38444134	1.166	NM_001254	CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr19_-_10305536	1.166		DNMT1	DNA (cytosine-5-)-methyltransferase 1
chr8_+_48873510	1.163		MCM4	minichromosome maintenance complex component 4
chr15_+_40763159	1.153	NM_130468	CHST14	carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr16_+_29817426	1.150		MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)
chr2_+_10262694	1.148	NM_001165931	RRM2	ribonucleotide reductase M2
chr8_-_124408669	1.146		ATAD2	ATPase family, AAA domain containing 2
chr1_+_242011471	1.135	NM_130398	EXO1	exonuclease 1
chr1_-_149783910	1.131	NM_001024599 NM_001161334	HIST2H2BF	histone cluster 2, H2bf
chr1_-_178062734	1.129		LOC100302401	uncharacterized LOC100302401
chr15_+_71184781	1.124	NM_001199017 NM_017691 NM_001199018	LRRC49	leucine rich repeat containing 49
chr7_-_99699030	1.113		MCM7	minichromosome maintenance complex component 7
chr1_+_242011544	1.109		EXO1	exonuclease 1
chr11_+_74303626	1.102	NM_006591	POLD3	polymerase (DNA-directed), delta 3, accessory subunit
chr5_-_79950307	1.097		DHFR	dihydrofolate reductase
chr18_-_46476708	1.080		SMAD7	SMAD family member 7
chr7_-_99698993	1.080		MCM7	minichromosome maintenance complex component 7
chr17_+_38444151	1.070		CDC6	cell division cycle 6 homolog (S. cerevisiae)
chr19_-_10305645	1.068	NM_001130823 NM_001379	DNMT1	DNA (cytosine-5-)-methyltransferase 1
chr13_+_34392205	1.060	NM_002915 NM_181558	RFC3	replication factor C (activator 1) 3, 38kDa
chr8_-_124408458	1.060		ATAD2	ATPase family, AAA domain containing 2
chr14_+_93673583	1.032		UBR7	ubiquitin protein ligase E3 component n-recognin 7 (putative)
chr3_-_48229328	1.023		CDC25A	cell division cycle 25 homolog A (S. pombe)
chr14_+_93673622	1.017		UBR7	ubiquitin protein ligase E3 component n-recognin 7 (putative)
chr7_-_44887567	1.014		H2AFV	H2A histone family, member V
chr17_-_3571819	1.005		TAX1BP3	Tax1 (human T-cell leukemia virus type I) binding protein 3
chr8_-_145669796	1.004	NM_013432	TONSL	tonsoku-like, DNA repair protein
chr6_-_27782517	1.004	NM_021066	HIST1H2AJ	histone cluster 1, H2aj
chr7_-_99698916	0.998		MCM7	minichromosome maintenance complex component 7
chr7_-_44887697	0.997	NM_012412 NM_138635 NM_201436 NM_201516 NM_201517	H2AFV	H2A histone family, member V
chr7_-_99699426	0.997	NM_005916	MCM7	minichromosome maintenance complex component 7
chr14_+_93673400	0.996	NM_175748	UBR7	ubiquitin protein ligase E3 component n-recognin 7 (putative)
chr10_-_21786186	0.996		C10orf114	chromosome 10 open reading frame 114
chr8_-_67525426	0.995	NM_001080416 NM_001144755	MYBL1 LOC645895	v-myb myeloblastosis viral oncogene homolog (avian)-like 1 uncharacterized LOC645895
chr6_-_27860927	0.995	NM_003514	HIST1H2AM	histone cluster 1, H2am
chr6_+_27806322	0.994	NM_003520	HIST1H2BN	histone cluster 1, H2bn
chr16_+_3019466	0.993		PAQR4	progestin and adipoQ receptor family member IV
chr20_-_60982334	0.993	NM_031215	CABLES2	Cdk5 and Abl enzyme substrate 2
chr16_+_3019341	0.980	NM_152341	PAQR4	progestin and adipoQ receptor family member IV
chr13_+_32889594	0.978	NM_000059	BRCA2	breast cancer 2, early onset
chr8_-_124408665	0.973		ATAD2	ATPase family, AAA domain containing 2
chr10_-_21786205	0.970	NM_001010911	C10orf114	chromosome 10 open reading frame 114
chr13_+_34392254	0.964		RFC3	replication factor C (activator 1) 3, 38kDa
chr9_-_104500861	0.954	NM_133445	GRIN3A	glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
chr11_+_125495853	0.953		CHEK1	checkpoint kinase 1
chrX_-_106243198	0.953		MORC4	MORC family CW-type zinc finger 4
chr14_+_93673628	0.937		UBR7	ubiquitin protein ligase E3 component n-recognin 7 (putative)
chr1_-_110052285	0.934	NM_020703	AMIGO1	adhesion molecule with Ig-like domain 1
chrX_+_24712063	0.930	NM_016937	POLA1	polymerase (DNA directed), alpha 1, catalytic subunit
chrX_-_106243442	0.923	NM_001085354 NM_024657	MORC4	MORC family CW-type zinc finger 4
chr6_-_27100528	0.921	NM_021058	HIST1H2BJ	histone cluster 1, H2bj
chr15_-_40401041	0.920	NM_001003940	BMF	Bcl2 modifying factor
chr6_+_31126340	0.912		TCF19	transcription factor 19
chr15_+_80987953	0.908		FAM108C1	family with sequence similarity 108, member C1
chr8_-_95907423	0.901	NM_057749	CCNE2	cyclin E2
chr12_-_12849120	0.899	NM_006143	GPR19	G protein-coupled receptor 19
chr3_-_10067989	0.892		CIDECP	cell death-inducing DFFA-like effector c pseudogene
chr9_-_35079520	0.882		FANCG	Fanconi anemia, complementation group G
chr10_-_75006963	0.880	NM_015190	DNAJC9	DnaJ (Hsp40) homolog, subfamily C, member 9
chr13_+_78271820	0.874	NM_001242868	SLAIN1	SLAIN motif family, member 1
chr10_-_58121011	0.868		ZWINT	ZW10 interactor
chr15_-_66648991	0.868	NM_017858	TIPIN	TIMELESS interacting protein
chr8_-_124408688	0.868	NM_014109	ATAD2	ATPase family, AAA domain containing 2
chr10_-_58121019	0.867	NM_001005413 NM_007057 NM_032997	ZWINT	ZW10 interactor
chr7_-_44887620	0.857		H2AFV	H2A histone family, member V
chr16_-_85722503	0.853		GINS2	GINS complex subunit 2 (Psf2 homolog)
chr3_+_40547529	0.853	NM_175888	ZNF620	zinc finger protein 620
chr19_-_15560761	0.848	NM_021241	WIZ	widely interspaced zinc finger motifs
chr13_+_115079943	0.845	NM_001164144 NM_001164145 NM_032436	CHAMP1	chromosome alignment maintaining phosphoprotein 1
chr11_+_77850824	0.845		LOC100289388	uncharacterized LOC100289388
chr11_-_695069	0.840		DEAF1	deformed epidermal autoregulatory factor 1 (Drosophila)
chr6_+_42928464	0.832	NM_018960	GNMT	glycine N-methyltransferase
chr2_+_39893021	0.826	NM_152390	TMEM178	transmembrane protein 178
chr8_-_65711104	0.825	NM_004820	CYP7B1	cytochrome P450, family 7, subfamily B, polypeptide 1
chr12_+_117176085	0.825	NM_001109903 NM_032814	RNFT2	ring finger protein, transmembrane 2
chr17_-_7197811	0.822		YBX2	Y box binding protein 2
chr7_-_44887663	0.819		H2AFV	H2A histone family, member V
chr1_+_33116748	0.818	NM_001135255 NM_005610 NM_001135256	RBBP4	retinoblastoma binding protein 4
chr16_+_58426297	0.816	NM_001126129 NM_001126130 NM_022770	GINS3	GINS complex subunit 3 (Psf3 homolog)
chr5_-_93954176	0.799	NM_001145678 NM_173665	KIAA0825	KIAA0825
chr10_-_14879967	0.798	NM_001029954	CDNF	cerebral dopamine neurotrophic factor
chr20_+_5891973	0.794	NM_001819	CHGB	chromogranin B (secretogranin 1)
chr3_-_48229800	0.792	NM_001789 NM_201567	CDC25A	cell division cycle 25 homolog A (S. pombe)
chr9_-_35079751	0.792	NM_004629	FANCG	Fanconi anemia, complementation group G
chr16_+_29818694	0.789		MAZ	MYC-associated zinc finger protein (purine-binding transcription factor)
chr9_+_130922471	0.787	NM_024112	C9orf16	chromosome 9 open reading frame 16
chr1_+_61547625	0.787	NM_001134673 NM_005595	NFIA	nuclear factor I/A
chr19_+_8455265	0.786		RAB11B	RAB11B, member RAS oncogene family
chr17_-_3571905	0.782	NM_001204698 NM_014604	TAX1BP3	Tax1 (human T-cell leukemia virus type I) binding protein 3
chr16_-_85722587	0.780	NM_016095	GINS2	GINS complex subunit 2 (Psf2 homolog)
chrX_+_24712043	0.775		POLA1	polymerase (DNA directed), alpha 1, catalytic subunit
chr2_-_139537803	0.769	NM_007226	NXPH2	neurexophilin 2
chr6_+_31126114	0.767	NM_001077511 NM_007109	TCF19	transcription factor 19
chr6_+_21666645	0.765		LINC00340	long intergenic non-protein coding RNA 340
chr11_-_59436366	0.764		PATL1	protein associated with topoisomerase II homolog 1 (yeast)
chr6_+_35182182	0.763	NM_152753	SCUBE3	signal peptide, CUB domain, EGF-like 3
chr3_+_44803208	0.763	NM_020242	KIF15	kinesin family member 15
chr10_-_103454687	0.758	NM_022039	FBXW4	F-box and WD repeat domain containing 4
chr11_+_10829561	0.757		LOC144017	uncharacterized LOC144017
chr19_+_18530423	0.757
chr17_+_29158948	0.756	NM_024857	ATAD5	ATPase family, AAA domain containing 5
chr6_-_58287651	0.752		GUSBP4	glucuronidase, beta pseudogene 4
chr3_+_38388288	0.751		XYLB	xylulokinase homolog (H. influenzae)
chr12_-_9600763	0.750		DDX11 DDX12P	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 11 DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 12, pseudogene
chr9_+_504661	0.750	NM_015158	KANK1	KN motif and ankyrin repeat domains 1
chr3_+_44803280	0.750		KIF15	kinesin family member 15
chr22_+_50946654	0.747		NCAPH2	non-SMC condensin II complex, subunit H2
chr17_-_33288475	0.736	NM_001193529 NM_001193530 NM_006584	CCT6B	chaperonin containing TCP1, subunit 6B (zeta 2)
chr16_-_74401792	0.722
chr1_+_212209112	0.720		DTL	denticleless homolog (Drosophila)
chrX_-_53449610	0.718	NM_006306	SMC1A	structural maintenance of chromosomes 1A
chr1_-_28241233	0.717	NM_002946	RPA2	replication protein A2, 32kDa
chr1_-_16161279	0.716
chr7_+_120590816	0.707	NM_019071 NM_198267	ING3	inhibitor of growth family, member 3
chr19_-_1095316	0.699		POLR2E	polymerase (RNA) II (DNA directed) polypeptide E, 25kDa

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
17.48	6.42e-19	GO:0051325	interphase
16.94	1.28e-17	GO:0051329	interphase of mitotic cell cycle
27.39	5.00e-17	GO:0000082	G1/S transition of mitotic cell cycle
21.76	2.18e-15	GO:0006260	DNA replication
30.29	2.75e-15	GO:0051320	S phase
9.78	1.65e-14	GO:0006259	DNA metabolic process
28.64	9.74e-14	GO:0000084	S phase of mitotic cell cycle
6.73	9.91e-14	GO:0007049	cell cycle
76.46	3.39e-13	GO:0006271	DNA strand elongation involved in DNA replication
8.44	3.59e-13	GO:0022403	cell cycle phase
71.37	6.99e-13	GO:0022616	DNA strand elongation
37.39	1.07e-12	GO:0006261	DNA-dependent DNA replication
9.06	2.57e-12	GO:0000278	mitotic cell cycle
7.17	1.03e-11	GO:0022402	cell cycle process
26.99	4.54e-11	GO:0031497	chromatin assembly
25.66	8.01e-11	GO:0034728	nucleosome organization
8.11	1.01e-10	GO:0051276	chromosome organization
19.30	1.89e-10	GO:0071103	DNA conformation change
3.74	5.40e-10	GO:0090304	nucleic acid metabolic process
75.69	6.97e-10	GO:0006270	DNA-dependent DNA replication initiation
20.61	9.28e-10	GO:0006323	DNA packaging
25.87	9.95e-10	GO:0006334	nucleosome assembly
4.32	1.12e-09	GO:0034645	cellular macromolecule biosynthetic process
4.26	1.49e-09	GO:0009059	macromolecule biosynthetic process
7.56	1.57e-09	GO:0051726	regulation of cell cycle
19.39	1.82e-09	GO:0006333	chromatin assembly or disassembly
22.45	4.21e-09	GO:0065004	protein-DNA complex assembly
21.25	7.35e-09	GO:0071824	protein-DNA complex subunit organization
27.46	7.69e-09	GO:0000216	M/G1 transition of mitotic cell cycle
10.32	9.31e-09	GO:0010564	regulation of cell cycle process
3.10	3.22e-08	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
71.37	4.44e-08	GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle
7.78	3.89e-07	GO:0006325	chromatin organization
3.07	5.14e-07	GO:0009058	biosynthetic process
2.68	6.68e-07	GO:0006807	nitrogen compound metabolic process
3.10	9.64e-07	GO:0044249	cellular biosynthetic process
2.69	1.33e-06	GO:0034641	cellular nitrogen compound metabolic process
2.29	1.43e-06	GO:0044260	cellular macromolecule metabolic process
11.67	2.70e-06	GO:0000075	cell cycle checkpoint
62.60	3.66e-06	GO:0032201	telomere maintenance via semi-conservative replication
11.23	3.90e-06	GO:0071156	regulation of cell cycle arrest
59.48	4.87e-06	GO:0000722	telomere maintenance via recombination
3.62	6.39e-06	GO:0006996	organelle organization
2.08	1.28e-05	GO:0043170	macromolecule metabolic process
29.74	1.29e-05	GO:0000723	telomere maintenance
29.14	1.46e-05	GO:0032200	telomere organization
45.75	2.03e-05	GO:0006312	mitotic recombination
14.11	2.25e-05	GO:0006310	DNA recombination
7.78	2.98e-05	GO:0034622	cellular macromolecular complex assembly
79.30	4.29e-05	GO:0071897	DNA biosynthetic process
38.38	5.16e-05	GO:0010833	telomere maintenance via telomere lengthening
5.27	5.39e-05	GO:0065003	macromolecular complex assembly
6.37	6.32e-05	GO:0034621	cellular macromolecular complex subunit organization
4.73	7.27e-05	GO:0043933	macromolecular complex subunit organization
59.48	1.56e-04	GO:0006297	nucleotide-excision repair, DNA gap filling
4.02	2.37e-04	GO:0022607	cellular component assembly
2.55	5.03e-04	GO:0071842	cellular component organization at cellular level
4.59	7.64e-04	GO:0071844	cellular component assembly at cellular level
2.46	9.84e-04	GO:0071841	cellular component organization or biogenesis at cellular level
3.59	1.05e-03	GO:0044085	cellular component biogenesis
89.21	1.31e-03	GO:0000731	DNA synthesis involved in DNA repair
6.75	1.65e-03	GO:0006281	DNA repair
13.11	1.76e-03	GO:0060249	anatomical structure homeostasis
1.69	3.01e-03	GO:0044237	cellular metabolic process
28.00	3.77e-03	GO:0000080	G1 phase of mitotic cell cycle
28.00	3.77e-03	GO:0006284	base-excision repair
2.14	4.62e-03	GO:0016043	cellular component organization
1.66	5.01e-03	GO:0044238	primary metabolic process
25.73	5.32e-03	GO:0051318	G1 phase
5.06	5.81e-03	GO:0006974	response to DNA damage stimulus
23.22	8.06e-03	GO:0006283	transcription-coupled nucleotide-excision repair
2.07	8.49e-03	GO:0071840	cellular component organization or biogenesis
2.30	9.25e-03	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.30	9.92e-03	GO:0009987	cellular process
3.81	1.30e-02	GO:0033554	cellular response to stress
3.53	1.31e-02	GO:0006357	regulation of transcription from RNA polymerase II promoter
2.23	1.51e-02	GO:0051171	regulation of nitrogen compound metabolic process
158.58	1.85e-02	GO:0010216	maintenance of DNA methylation
158.58	1.85e-02	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation
1.56	1.92e-02	GO:0050794	regulation of cellular process
5.68	2.03e-02	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
35.69	2.57e-02	GO:0006298	mismatch repair
2.36	2.73e-02	GO:0051252	regulation of RNA metabolic process
1.48	2.74e-02	GO:0065007	biological regulation
2.20	3.00e-02	GO:0031326	regulation of cellular biosynthetic process
2.17	3.56e-02	GO:0009889	regulation of biosynthetic process
1.51	4.30e-02	GO:0008152	metabolic process
1.94	4.47e-02	GO:0031323	regulation of cellular metabolic process
2.19	4.90e-02	GO:0010468	regulation of gene expression

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
12.48	1.80e-18	GO:0044427	chromosomal part
35.06	4.96e-17	GO:0032993	protein-DNA complex
10.45	9.39e-17	GO:0005694	chromosome
5.82	1.64e-15	GO:0005654	nucleoplasm
39.65	1.78e-12	GO:0000786	nucleosome
2.31	4.34e-12	GO:0005634	nucleus
178.40	5.16e-12	GO:0042555	MCM complex
4.22	1.01e-11	GO:0031981	nuclear lumen
13.46	2.93e-10	GO:0000785	chromatin
3.56	3.15e-10	GO:0070013	intracellular organelle lumen
3.49	5.35e-10	GO:0043233	organelle lumen
3.58	7.33e-10	GO:0044428	nuclear part
3.43	8.23e-10	GO:0031974	membrane-enclosed lumen
45.01	6.23e-09	GO:0005657	replication fork
2.09	2.35e-08	GO:0044446	intracellular organelle part
2.06	3.97e-08	GO:0044422	organelle part
5.63	3.49e-07	GO:0044451	nucleoplasm part
54.07	1.27e-06	GO:0043596	nuclear replication fork
12.61	1.30e-06	GO:0044454	nuclear chromosome part
2.41	1.74e-06	GO:0032991	macromolecular complex
1.56	3.02e-06	GO:0043231	intracellular membrane-bounded organelle
1.56	3.16e-06	GO:0043227	membrane-bounded organelle
10.21	8.02e-06	GO:0000228	nuclear chromosome
2.54	2.32e-05	GO:0043228	non-membrane-bounded organelle
2.54	2.32e-05	GO:0043232	intracellular non-membrane-bounded organelle
8.82	2.76e-05	GO:0005667	transcription factor complex
55.98	3.16e-05	GO:0030894	replisome
55.98	3.16e-05	GO:0043601	nuclear replisome
1.43	6.57e-05	GO:0043229	intracellular organelle
1.43	7.07e-05	GO:0043226	organelle
1.26	4.42e-03	GO:0044424	intracellular part
95.15	9.54e-03	GO:0005663	DNA replication factor C complex
1.23	1.24e-02	GO:0005622	intracellular
2.01	1.25e-02	GO:0043234	protein complex
79.30	1.43e-02	GO:0005658	alpha DNA polymerase:primase complex

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
3.95	8.74e-14	GO:0003677	DNA binding
2.86	8.32e-10	GO:0003676	nucleic acid binding
237.86	1.37e-03	GO:0030617	transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity
1.24	4.42e-03	GO:0005488	binding
7.73	7.85e-03	GO:0043566	structure-specific DNA binding
15.12	9.85e-03	GO:0008094	DNA-dependent ATPase activity
27.46	1.28e-02	GO:0003887	DNA-directed DNA polymerase activity
24.62	1.78e-02	GO:0034061	DNA polymerase activity
23.80	1.97e-02	GO:0004003	ATP-dependent DNA helicase activity
67.97	2.85e-02	GO:0034713	type I transforming growth factor beta receptor binding
17.85	4.67e-02	GO:0003678	DNA helicase activity