Motif ID: EOMES.p2

Z-value: 0.605


Transcription factors associated with EOMES.p2:

Gene SymbolEntrez IDGene Name
EOMES 8320 eomesodermin

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
EOMEShg19_v1_chr3_-_27764197_277642050.177.4e-01Click!


Activity profile for motif EOMES.p2.

activity profile for motif EOMES.p2


Sorted Z-values histogram for motif EOMES.p2

Sorted Z-values for motif EOMES.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EOMES.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_92680784 0.546 ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr1_-_11907741 0.522 NM_006172
NPPA
natriuretic peptide A
chr1_+_26737306 0.362 LIN28A
lin-28 homolog A (C. elegans)
chr10_-_92681025 0.361 NM_014391
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr12_+_124773709 0.292 NM_181709
FAM101A
family with sequence similarity 101, member A
chr1_-_156786500 0.286 NM_001161441
NM_001161442
NM_001161444
NM_003975
SH2D2A



SH2 domain containing 2A



chr11_+_124439892 0.266 NM_001005194
OR8A1
olfactory receptor, family 8, subfamily A, member 1
chr6_+_39760138 0.259


chr16_-_67965754 0.245 NM_001907
CTRL
chymotrypsin-like
chr6_-_26027479 0.237 NM_003544
HIST1H4B
histone cluster 1, H4b
chr1_-_205290756 0.219 NM_030952
NUAK2
NUAK family, SNF1-like kinase, 2
chr18_-_24442534 0.219 NM_004028
AQP4
aquaporin 4
chr14_+_51026742 0.211 NM_015915
NM_181598
ATL1

atlastin GTPase 1

chr1_+_153600859 0.209 NM_006271
S100A1
S100 calcium binding protein A1
chr2_-_100722328 0.205 AFF3
AF4/FMR2 family, member 3
chr6_-_135271206 0.205 NM_001193480
NM_022568
NM_170771
ALDH8A1


aldehyde dehydrogenase 8 family, member A1


chr3_-_133748727 0.205 SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr3_-_133748828 0.197 NM_005630
SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr6_-_130536417 0.191 NM_152552
SAMD3
sterile alpha motif domain containing 3
chr8_-_42234562 0.188 NM_014420
DKK4
dickkopf homolog 4 (Xenopus laevis)
chr2_-_157189040 0.179 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr2_-_192711651 0.174 SDPR
serum deprivation response
chrM_+_8364 0.173


chr10_+_114135965 0.160 ACSL5
acyl-CoA synthetase long-chain family member 5
chr17_+_7533452 0.159 NM_001040
NM_001146279
NM_001146280
NM_001146281
SHBG



sex hormone-binding globulin



chrX_+_102862833 0.146 NM_001006933
NM_032926
TCEAL3

transcription elongation factor A (SII)-like 3

chr6_+_84222252 0.144 PRSS35
protease, serine, 35
chr13_+_99058147 0.144


chr1_+_38022514 0.143 NM_003462
DNALI1
dynein, axonemal, light intermediate chain 1
chr11_+_111749947 0.140 NM_022761
C11orf1
chromosome 11 open reading frame 1
chr19_-_7990974 0.138 NM_206833
CTXN1
cortexin 1
chrX_+_122318095 0.135 NM_000828
NM_007325
GRIA3

glutamate receptor, ionotrophic, AMPA 3

chr8_-_120651019 0.132 NM_001040092
NM_001130863
NM_006209
ENPP2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr11_-_111750144 0.131 NM_138378
FDXACB1
ferredoxin-fold anticodon binding domain containing 1
chr1_+_174843523 0.129 NM_001243763
RABGAP1L
RAB GTPase activating protein 1-like
chr1_+_226411318 0.129 NM_031944
MIXL1
Mix paired-like homeobox
chr17_-_39092714 0.128 KRT23
keratin 23 (histone deacetylase inducible)
chr21_-_31852631 0.126 NM_181607
KRTAP19-1
keratin associated protein 19-1
chr3_-_71542628 0.122 FOXP1
forkhead box P1
chr16_-_81110803 0.121 NM_001100873
NM_152337
C16orf46

chromosome 16 open reading frame 46

chr14_-_23446431 0.120 NM_198086
AJUBA
ajuba LIM protein
chr1_+_26737232 0.118 NM_024674
LIN28A
lin-28 homolog A (C. elegans)
chrM_-_9203 0.118


chr11_-_2182408 0.113 NM_000207
NM_001185097
NM_001185098
NM_001042376
INS


INS-IGF2
insulin


INS-IGF2 readthrough
chr15_+_63889551 0.107 NM_203373
FBXL22
F-box and leucine-rich repeat protein 22
chrX_+_48336379 0.106 NM_177434
FTSJ1
FtsJ homolog 1 (E. coli)
chr7_+_107221203 0.106 NM_001008405
BCAP29
B-cell receptor-associated protein 29
chr10_+_114135937 0.104 NM_016234
ACSL5
acyl-CoA synthetase long-chain family member 5
chr5_+_176811431 0.104 NM_001167579
NM_003052
SLC34A1

solute carrier family 34 (sodium phosphate), member 1

chr5_+_140749830 0.099 NM_018924
NM_032097
PCDHGB3

protocadherin gamma subfamily B, 3

chr1_+_87797301 0.098


chr2_-_100758970 0.098 NM_002285
AFF3
AF4/FMR2 family, member 3
chr1_-_202858225 0.097 NM_002871
RABIF
RAB interacting factor
chr6_+_39760148 0.096 NM_001201427
DAAM2
dishevelled associated activator of morphogenesis 2
chr14_+_55034633 0.095 SAMD4A
sterile alpha motif domain containing 4A
chr11_+_56143099 0.095 NM_001005204
NM_001013356
OR8U1
OR8U8
olfactory receptor, family 8, subfamily U, member 1
olfactory receptor, family 8, subfamily U, member 8
chr8_-_72268720 0.095 NM_172058
NM_172059
NM_172060
EYA1


eyes absent homolog 1 (Drosophila)


chr17_+_56406294 0.095 LOC100506779
uncharacterized LOC100506779
chr3_-_42843217 0.094


chr11_-_65314049 0.093 LTBP3
latent transforming growth factor beta binding protein 3
chr4_+_109543670 0.092 RPL34
ribosomal protein L34
chr3_+_120627026 0.092 NM_014980
STXBP5L
syntaxin binding protein 5-like
chr10_+_81065875 0.091 ZMIZ1
zinc finger, MIZ-type containing 1
chr5_+_179220985 0.091 NM_145867
LTC4S
leukotriene C4 synthase
chr2_+_27719702 0.091 NM_001486
GCKR
glucokinase (hexokinase 4) regulator
chr4_+_86396251 0.090 NM_001025616
ARHGAP24
Rho GTPase activating protein 24
chr9_+_127420690 0.090 MIR181A2HG
MIR181A2 host gene (non-protein coding)
chr10_-_105238996 0.089 NM_001129742
CALHM3
calcium homeostasis modulator 3
chrX_-_133930234 0.089 NM_001170756
NM_145284
FAM122B

family with sequence similarity 122B

chr2_+_171572698 0.088 SP5
Sp5 transcription factor
chr10_+_24498088 0.088 KIAA1217
KIAA1217
chr2_-_70189396 0.087 NM_152792
ASPRV1
aspartic peptidase, retroviral-like 1
chrX_+_37865834 0.087 NM_001163335
NM_138780
SYTL5

synaptotagmin-like 5

chr2_-_74753311 0.086 NM_133637
DQX1
DEAQ box RNA-dependent ATPase 1
chr16_+_69140121 0.085 NM_138612
HAS3
hyaluronan synthase 3
chr15_+_65914269 0.085 NM_004727
SLC24A1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
chr2_+_27799388 0.085 NM_032266
C2orf16
chromosome 2 open reading frame 16
chr6_+_99872769 0.084


chr12_+_32654976 0.083 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr17_+_42925278 0.081 NM_016438
HIGD1B
HIG1 hypoxia inducible domain family, member 1B
chr1_+_147013181 0.078 NM_004326
BCL9
B-cell CLL/lymphoma 9
chr9_-_104500861 0.077 NM_133445
GRIN3A
glutamate receptor, ionotropic, N-methyl-D-aspartate 3A
chr19_-_16242996 0.077


chr14_-_60043548 0.077 NM_001164399
C14orf38
chromosome 14 open reading frame 38
chr1_+_33219544 0.076


chr12_-_56359794 0.075 NM_001200053
NM_001200054
PMEL

premelanosome protein

chr1_-_241799101 0.075 NM_001821
CHML
choroideremia-like (Rab escort protein 2)
chr4_+_156824846 0.075 NM_005651
TDO2
tryptophan 2,3-dioxygenase
chr15_-_40857178 0.073 C15orf57
chromosome 15 open reading frame 57
chrM_+_9217 0.073


chr1_-_27998658 0.072 IFI6
interferon, alpha-inducible protein 6
chr4_-_140222357 0.072 NM_001184986
NM_001184991
NM_002494
NDUFC1


NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa


chr3_+_151488214 0.072 LOC201651
arylacetamide deacetylase (esterase) pseudogene
chr1_-_153600714 0.072 NM_005979
S100A13
S100 calcium binding protein A13
chr1_-_28969516 0.071 NM_001135218
NM_005644
TAF12

TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa

chrM_+_9182 0.070


chr19_+_48867650 0.069 NM_012451
SYNGR4
synaptogyrin 4
chr3_+_151985828 0.069 NM_021038
NM_207292
MBNL1

muscleblind-like (Drosophila)

chr19_-_14260728 0.068 LPHN1
latrophilin 1
chr12_+_96252705 0.067 NM_003095
SNRPF
small nuclear ribonucleoprotein polypeptide F
chr11_-_124981458 0.067 TMEM218
transmembrane protein 218
chr4_+_15779887 0.067 NM_001775
CD38
CD38 molecule
chr19_-_46285752 0.067 NM_001081560
NM_001081562
NM_004409
DMPK


dystrophia myotonica-protein kinase


chr2_-_56151273 0.067 NM_001039348
NM_001039349
EFEMP1

EGF containing fibulin-like extracellular matrix protein 1

chr5_-_114515733 0.066 NM_001017397
NM_001017398
NM_018700
TRIM36


tripartite motif containing 36


chr6_-_26108320 0.065 NM_005323
HIST1H1T
histone cluster 1, H1t
chrM_+_8857 0.064


chr8_+_21900389 0.064 NM_003867
FGF17
fibroblast growth factor 17
chr6_+_106960326 0.064 AIM1
absent in melanoma 1
chr7_+_72396799 0.064 POM121
POM121 membrane glycoprotein
chr1_-_113257873 0.063 NM_005167
PPM1J
protein phosphatase, Mg2+/Mn2+ dependent, 1J
chr1_+_27101217 0.063 ARID1A
AT rich interactive domain 1A (SWI-like)
chr14_-_23288912 0.062 NM_001126106
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr8_+_38965049 0.062 NM_145004
ADAM32
ADAM metallopeptidase domain 32
chr18_+_54424444 0.062 WDR7
WD repeat domain 7
chr1_+_26503973 0.062 NM_006314
CNKSR1
connector enhancer of kinase suppressor of Ras 1
chr13_-_50656088 0.061 DLEU2
deleted in lymphocytic leukemia 2 (non-protein coding)
chr20_+_32250089 0.061 NM_080825
C20orf144
chromosome 20 open reading frame 144
chr7_-_80548322 0.060 SEMA3C
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chrX_-_69509714 0.060 NM_016484
PDZD11
PDZ domain containing 11
chr12_+_26348488 0.060 NM_005086
SSPN
sarcospan (Kras oncogene-associated gene)
chr10_-_16564003 0.060 NM_001010908
C1QL3
complement component 1, q subcomponent-like 3
chr10_+_24497719 0.059 NM_001098501
NM_019590
KIAA1217

KIAA1217

chr22_+_40441371 0.059 TNRC6B
trinucleotide repeat containing 6B
chr1_-_85930610 0.059 DDAH1
dimethylarginine dimethylaminohydrolase 1
chr14_+_105941061 0.058 NM_001312
CRIP2
cysteine-rich protein 2
chr12_+_7169192 0.058


chr8_-_13372183 0.057 NM_024767
NM_182643
DLC1

deleted in liver cancer 1

chrX_-_32430370 0.057 NM_004011
NM_004012
DMD

dystrophin

chr2_+_28616360 0.057 FOSL2
FOS-like antigen 2
chr7_+_123295860 0.057 NM_207163
LMOD2
leiomodin 2 (cardiac)
chrX_-_106146546 0.057 NM_001171706
NM_138382
RIPPLY1

ripply1 homolog (zebrafish)

chr2_-_25474948 0.056 NM_153759
DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr11_+_33350076 0.056 HIPK3
homeodomain interacting protein kinase 3
chr2_-_200322699 0.056 NM_001172509
SATB2
SATB homeobox 2
chr2_-_74734498 0.056 PCGF1
polycomb group ring finger 1
chr8_+_144766620 0.055 NM_001100598
NM_001100599
NM_173831
ZNF707


zinc finger protein 707


chr5_-_49737198 0.055 EMB
embigin
chr4_+_160188997 0.055 NM_014247
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr1_-_149859465 0.055 NM_175065
HIST2H2AB
HIST2H2BE
histone cluster 2, H2ab
histone cluster 2, H2be
chr16_+_2653350 0.055 LOC652276
potassium channel tetramerisation domain containing 5 pseudogene
chr11_-_10590078 0.054 NM_006691
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr9_-_4152182 0.054 NM_152629
GLIS3
GLIS family zinc finger 3
chrX_-_15683153 0.054 NM_020665
TMEM27
transmembrane protein 27
chr1_+_61547388 0.053 NM_001145512
NFIA
nuclear factor I/A
chr7_+_107220622 0.053 BCAP29
B-cell receptor-associated protein 29
chr11_+_66824285 0.053 NM_014578
RHOD
ras homolog gene family, member D
chr1_+_145507556 0.053 NM_005105
RBM8A
RNA binding motif protein 8A
chr11_-_62521533 0.052 NM_024784
ZBTB3
zinc finger and BTB domain containing 3
chr7_-_135412921 0.052 NM_012450
SLC13A4
solute carrier family 13 (sodium/sulfate symporters), member 4
chr3_-_12941547 0.052 IQSEC1
IQ motif and Sec7 domain 1
chr11_+_45907198 0.050 MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr10_+_114154522 0.050 ACSL5
acyl-CoA synthetase long-chain family member 5
chr6_-_26124130 0.050 NM_003526
HIST1H2BG
HIST1H2BC
histone cluster 1, H2bg
histone cluster 1, H2bc
chr2_+_233404436 0.050 NM_005199
CHRNG
cholinergic receptor, nicotinic, gamma
chr17_-_1553099 0.050 NM_031430
RILP
Rab interacting lysosomal protein
chr3_-_119379269 0.049 NM_022135
POPDC2
popeye domain containing 2
chr8_-_8239188 0.049 NM_001080826
SGK223
homolog of rat pragma of Rnd2
chr5_+_154092461 0.049 NM_015315
LARP1
La ribonucleoprotein domain family, member 1
chr18_-_24445652 0.049 NM_001650
AQP4
aquaporin 4
chr1_+_199996729 0.049 NM_003822
NM_205860
NR5A2

nuclear receptor subfamily 5, group A, member 2

chr7_-_92848837 0.048 NM_198151
HEPACAM2
HEPACAM family member 2
chr2_-_25468909 0.048 DNMT3A
DNA (cytosine-5-)-methyltransferase 3 alpha
chr1_+_61924621 0.048 NFIA
nuclear factor I/A
chr16_-_75282137 0.048 NM_001170719
BCAR1
breast cancer anti-estrogen resistance 1
chr22_+_42196587 0.048 NM_024821
CCDC134
coiled-coil domain containing 134
chrM_+_1670 0.048


chr17_-_8198605 0.047 SLC25A35
solute carrier family 25, member 35
chr2_-_151344145 0.047 NM_005168
RND3
Rho family GTPase 3
chr12_+_120933911 0.046 DYNLL1
dynein, light chain, LC8-type 1
chr5_-_132272803 0.046


chr7_+_100271427 0.046 GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr1_-_52456292 0.046 NM_002867
RAB3B
RAB3B, member RAS oncogene family
chr7_+_100271483 0.046 GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr3_+_49506079 0.046 NM_001177643
DAG1
dystroglycan 1 (dystrophin-associated glycoprotein 1)
chr16_+_2817654 0.045 SRRM2
serine/arginine repetitive matrix 2
chr11_-_66112537 0.045 NM_001024957
NM_015399
BRMS1

breast cancer metastasis suppressor 1

chr17_-_43502992 0.045 NM_199282
ARHGAP27
Rho GTPase activating protein 27
chr7_-_150652861 0.044 NM_001204798
NM_172057
KCNH2

potassium voltage-gated channel, subfamily H (eag-related), member 2

chr21_-_36421461 0.044 RUNX1
runt-related transcription factor 1
chr11_+_69061599 0.044 NM_138768
MYEOV
myeloma overexpressed (in a subset of t(11;14) positive multiple myelomas)
chr11_+_66824308 0.044 RHOD
ras homolog gene family, member D
chrX_-_32173585 0.044 NM_004013
NM_004020
NM_004021
NM_004022
NM_004023
DMD




dystrophin




chr17_-_40306988 0.043 RAB5C
RAB5C, member RAS oncogene family
chr15_+_40861491 0.043 RPUSD2
RNA pseudouridylate synthase domain containing 2
chr14_+_51026853 0.043 ATL1
atlastin GTPase 1
chr11_-_67275549 0.042 CDK2AP2
cyclin-dependent kinase 2 associated protein 2
chr21_-_36421578 0.042 RUNX1
runt-related transcription factor 1
chr5_-_112630557 0.042 NM_002387
MCC
mutated in colorectal cancers
chr1_+_55007927 0.042 ACOT11
acyl-CoA thioesterase 11
chr4_+_71062241 0.042 NM_017855
ODAM
odontogenic, ameloblast asssociated
chr14_+_100239935 0.041 EML1
echinoderm microtubule associated protein like 1
chr21_-_36421195 0.041 RUNX1
runt-related transcription factor 1
chr6_+_106959729 0.041 NM_001624
AIM1
absent in melanoma 1
chr2_-_192711923 0.040 NM_004657
SDPR
serum deprivation response
chr11_+_89392464 0.040 NM_153696
FOLH1B
folate hydrolase 1B
chr14_-_21572789 0.040 NM_001102454
ZNF219
zinc finger protein 219
chr10_-_126432784 0.040 FAM53B
family with sequence similarity 53, member B
chr21_-_27253197 0.040 APP
amyloid beta (A4) precursor protein
chr22_-_40859423 0.039 MKL1
megakaryoblastic leukemia (translocation) 1

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.