Motif ID: FOX{C1,C2}.p2

Z-value: 0.326


Transcription factors associated with FOX{C1,C2}.p2:

Gene SymbolEntrez IDGene Name
FOXC1 2296 forkhead box C1
FOXC2 2303 forkhead box C2 (MFH-1, mesenchyme forkhead 1)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOXC1hg19_v1_chr6_+_1611544_16116050.305.6e-01Click!


Activity profile for motif FOX{C1,C2}.p2.

activity profile for motif FOX{C1,C2}.p2


Sorted Z-values histogram for motif FOX{C1,C2}.p2

Sorted Z-values for motif FOX{C1,C2}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{C1,C2}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_96522457 0.197 NM_000769
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr22_+_31003069 0.169 NM_000355
NM_001184726
TCN2

transcobalamin II

chr21_-_43735462 0.158 TFF3
trefoil factor 3 (intestinal)
chr1_-_198906536 0.130 LOC100131234
familial acute myelogenous leukemia related factor
chr8_-_124749573 0.108 NM_001003954
NM_004306
ANXA13

annexin A13

chr11_+_111789600 0.107 NM_080659
C11orf52
chromosome 11 open reading frame 52
chr11_-_6790187 0.101 NM_001004490
OR2AG2
olfactory receptor, family 2, subfamily AG, member 2
chr4_-_2230957 0.092 NM_181808
POLN
polymerase (DNA directed) nu
chrX_-_130423199 0.086 IGSF1
immunoglobulin superfamily, member 1
chr11_+_111789658 0.084 C11orf52
chromosome 11 open reading frame 52
chr5_+_140174443 0.082 NM_018905
NM_031495
PCDHA2

protocadherin alpha 2

chr4_-_84035888 0.081 PLAC8
placenta-specific 8
chr7_-_98805088 0.081 NM_001145715
KPNA7
karyopherin alpha 7 (importin alpha 8)
chr1_-_1356823 0.077 NM_001145210
NM_001243535
NM_001243536
ANKRD65


ankyrin repeat domain 65


chr9_-_131644176 0.075 NM_001122671
NM_001122672
NM_004059
CCBL1


cysteine conjugate-beta lyase, cytoplasmic


chr4_+_120056938 0.074 NM_016599
MYOZ2
myozenin 2
chr14_+_95047758 0.074 SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr10_-_17171789 0.069 NM_001081
CUBN
cubilin (intrinsic factor-cobalamin receptor)
chr1_+_84768333 0.067 NM_001134664
SAMD13
sterile alpha motif domain containing 13
chr7_+_141618616 0.066 NM_001001656
OR9A4
olfactory receptor, family 9, subfamily A, member 4
chr11_+_120973374 0.065 NM_005422
TECTA
tectorin alpha
chr12_+_25205488 0.062 LRMP
lymphoid-restricted membrane protein
chr2_-_70520845 0.061 NM_003096
SNRPG
small nuclear ribonucleoprotein polypeptide G
chr7_-_92747269 0.059 SAMD9
sterile alpha motif domain containing 9
chr14_+_95047730 0.059 NM_000624
SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr4_-_84035908 0.059 NM_001130715
NM_016619
PLAC8

placenta-specific 8

chr6_-_41122025 0.057 NM_178174
TREML1
triggering receptor expressed on myeloid cells-like 1
chr7_-_92747317 0.055 NM_001193307
NM_017654
SAMD9

sterile alpha motif domain containing 9

chr2_+_48796158 0.054 NM_172311
STON1-GTF2A1L
STON1-GTF2A1L readthrough
chrX_+_115301957 0.054 NM_000686
AGTR2
angiotensin II receptor, type 2
chr3_-_9291251 0.054 NM_001033117
NM_014850
SRGAP3

SLIT-ROBO Rho GTPase activating protein 3

chr12_-_57030083 0.053 NM_013449
BAZ2A
bromodomain adjacent to zinc finger domain, 2A
chr17_+_48821106 0.051 LUC7L3
LUC7-like 3 (S. cerevisiae)
chr1_-_162346579 0.050 NM_182581
C1orf111
chromosome 1 open reading frame 111
chr7_-_14880954 0.050 NM_004080
NM_145695
DGKB

diacylglycerol kinase, beta 90kDa

chr6_-_117150197 0.049 NM_148963
GPRC6A
G protein-coupled receptor, family C, group 6, member A
chr11_-_116693907 0.048 NM_000482
APOA4
apolipoprotein A-IV
chr1_-_36948423 0.046 CSF3R
colony stimulating factor 3 receptor (granulocyte)
chr1_+_67632168 0.046 NM_144701
IL23R
interleukin 23 receptor
chr2_+_177016112 0.045 NM_014621
HOXD4
homeobox D4
chr5_-_35230548 0.044 PRLR
prolactin receptor
chr2_-_70520780 0.042 SNRPG
small nuclear ribonucleoprotein polypeptide G
chr12_-_9913415 0.041 NM_001781
CD69
CD69 molecule
chr12_-_24103953 0.041 SOX5
SRY (sex determining region Y)-box 5
chr3_+_118892363 0.041 NM_006952
UPK1B
uroplakin 1B
chr9_-_34397786 0.041 NM_032596
C9orf24
chromosome 9 open reading frame 24
chr4_-_159093523 0.040 FAM198B
family with sequence similarity 198, member B
chr14_+_24779356 0.040 NM_001164692
NM_019839
LTB4R2

leukotriene B4 receptor 2

chr5_-_160279045 0.040 NM_025153
ATP10B
ATPase, class V, type 10B
chr4_+_186131283 0.039 NM_031953
SNX25
sorting nexin 25
chr9_+_124048396 0.038 GSN
gelsolin
chr2_-_88427535 0.036 NM_001443
FABP1
fatty acid binding protein 1, liver
chr1_-_151118932 0.035 NM_001178061
NM_001178062
NM_030913
SEMA6C


sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C


chr15_-_58306185 0.035 NM_170697
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr10_+_7745341 0.035 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr1_+_45478420 0.033 UROD
uroporphyrinogen decarboxylase
chr10_+_7745354 0.033 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr4_-_100140330 0.033 NM_000672
NM_001102470
ADH6

alcohol dehydrogenase 6 (class V)

chr4_-_159093717 0.032 NM_016613
FAM198B
family with sequence similarity 198, member B
chr2_+_150187028 0.032 NM_194317
LYPD6
LY6/PLAUR domain containing 6
chr7_+_129906702 0.032 NM_001869
CPA2
carboxypeptidase A2 (pancreatic)
chrX_-_130423387 0.032 NM_001170961
NM_001170962
NM_001555
NM_205833
IGSF1



immunoglobulin superfamily, member 1



chr12_+_69742140 0.031 LYZ
lysozyme
chr21_-_43735705 0.031 NM_003226
TFF3
trefoil factor 3 (intestinal)
chr5_+_140180782 0.031 NM_018906
NM_031497
PCDHA3

protocadherin alpha 3

chr12_-_57634474 0.030 NM_020142
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr10_+_7745284 0.030 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr10_+_7745325 0.030 ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chrX_+_71364033 0.030 NM_207422
FLJ44635
TPT1-like protein
chr20_+_57470647 0.029 GNAS
GNAS complex locus
chr2_+_132480063 0.029 NM_013310
C2orf27A
chromosome 2 open reading frame 27A
chr22_+_39916563 0.029 NM_001675
NM_182810
ATF4

activating transcription factor 4 (tax-responsive enhancer element B67)

chr5_+_140201221 0.029 NM_018908
NM_031501
PCDHA5

protocadherin alpha 5

chr7_-_106301329 0.029 NM_175884
C7orf74
chromosome 7 open reading frame 74
chr12_+_69742130 0.028 NM_000239
LYZ
lysozyme
chr12_-_51611476 0.028 POU6F1
POU class 6 homeobox 1
chr12_+_47610244 0.028 FAM113B
family with sequence similarity 113, member B
chr1_-_26644755 0.028 NM_145345
UBXN11
UBX domain protein 11
chr2_-_188312872 0.027 NM_005795
CALCRL
calcitonin receptor-like
chr5_+_173472692 0.027 NM_015980
HMP19
HMP19 protein
chr6_+_1611544 0.027 FOXC1
forkhead box C1
chr2_-_87248942 0.027 NM_002665
NM_001032392
PLGLB2
PLGLB1
plasminogen-like B2
plasminogen-like B1
chr7_-_7758237 0.026 NM_002947
RPA3
replication protein A3, 14kDa
chr5_+_140710203 0.026 NM_018912
NM_031993
PCDHGA1

protocadherin gamma subfamily A, 1

chr6_+_123100860 0.026 FABP7
fatty acid binding protein 7, brain
chr2_-_120281801 0.025 SCTR
secretin receptor
chr17_-_64225496 0.025 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr5_-_172083569 0.025


chr12_+_54378929 0.025 NM_017409
HOXC10
homeobox C10
chr12_+_100867739 0.025 NR1H4
nuclear receptor subfamily 1, group H, member 4
chr5_+_140213968 0.025 NM_018910
NM_031852
PCDHA7

protocadherin alpha 7

chr8_-_145578502 0.025 NM_001252402
NM_001252404
C8ORFK29

uncharacterized LOC340393

chr10_+_7745229 0.024 NM_002216
ITIH2
inter-alpha-trypsin inhibitor heavy chain 2
chr6_-_64029847 0.024 NM_001143940
NM_016571
LGSN

lengsin, lens protein with glutamine synthetase domain

chr2_-_158300517 0.024 NM_004288
CYTIP
cytohesin 1 interacting protein
chr16_-_53737713 0.023 NM_001127897
NM_015272
RPGRIP1L

RPGRIP1-like

chr17_-_40897025 0.023 NM_001991
EZH1
enhancer of zeste homolog 1 (Drosophila)
chr16_+_24567628 0.023 RBBP6
retinoblastoma binding protein 6
chr12_+_100867550 0.023 NM_001206977
NM_001206978
NM_001206979
NM_005123
NR1H4



nuclear receptor subfamily 1, group H, member 4



chr2_+_102979096 0.022 NM_003855
IL18R1
interleukin 18 receptor 1
chr1_-_110933635 0.022 SLC16A4
solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
chr5_+_173472737 0.022 HMP19
HMP19 protein
chr17_+_40714176 0.021 COASY
CoA synthase
chr20_+_43211219 0.021 PKIG
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr9_+_116918230 0.021 NM_032888
COL27A1
collagen, type XXVII, alpha 1
chr11_-_16497917 0.021 NM_033326
SOX6
SRY (sex determining region Y)-box 6
chr11_+_66790815 0.021 NM_177963
SYT12
synaptotagmin XII
chr2_+_74120092 0.021 NM_001199893
NM_001615
ACTG2

actin, gamma 2, smooth muscle, enteric

chr12_-_102872329 0.021 NM_001111284
IGF1
insulin-like growth factor 1 (somatomedin C)
chr2_+_74120132 0.021 ACTG2
actin, gamma 2, smooth muscle, enteric
chr17_-_3599298 0.020 P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr17_-_7082654 0.020 NM_001197216
NM_001671
ASGR1

asialoglycoprotein receptor 1

chr14_+_100531745 0.020 NM_016337
EVL
Enah/Vasp-like
chr20_+_42143045 0.019 NM_015478
L3MBTL1
l(3)mbt-like 1 (Drosophila)
chr8_-_17555158 0.019 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr11_+_65271145 0.019


chr20_-_62199106 0.019 NM_033405
PRIC285
peroxisomal proliferator-activated receptor A interacting complex 285
chr14_+_95047792 0.018 SERPINA5
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
chr16_+_82068958 0.018 HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr17_+_79373539 0.018 NM_001080519
BAHCC1
BAH domain and coiled-coil containing 1
chr15_+_78384926 0.018 NM_001101404
SH2D7
SH2 domain containing 7
chr2_-_263982 0.018 SH3YL1
SH3 domain containing, Ysc84-like 1 (S. cerevisiae)
chr15_-_23892992 0.018 NM_019066
MAGEL2
MAGE-like 2
chr17_+_73472578 0.017 KIAA0195
KIAA0195
chr1_+_149871154 0.017 NM_016074
BOLA1
bolA homolog 1 (E. coli)
chr9_-_14910992 0.017 NM_144966
FREM1
FRAS1 related extracellular matrix 1
chr17_+_40714091 0.017 NM_001042529
NM_001042530
NM_001042531
NM_001042532
NM_025233
COASY




CoA synthase




chr21_-_27423423 0.017


chr15_-_83876165 0.017 NM_016073
HDGFRP3
hepatoma-derived growth factor, related protein 3
chr7_+_91924291 0.017


chr2_+_161993465 0.017 NM_004180
NM_133484
TANK

TRAF family member-associated NFKB activator

chr14_-_24777064 0.017


chr5_+_38845962 0.017 NM_003999
OSMR
oncostatin M receptor
chr17_-_7082559 0.017 ASGR1
asialoglycoprotein receptor 1
chr17_-_80797889 0.017 NM_024702
ZNF750
zinc finger protein 750
chr2_+_33701678 0.017 RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr3_-_100712248 0.016 NM_015429
ABI3BP
ABI family, member 3 (NESH) binding protein
chr17_+_40714164 0.016 COASY
CoA synthase
chr11_+_62475165 0.016 GNG3
guanine nucleotide binding protein (G protein), gamma 3
chr8_-_109799769 0.016 NM_153015
TMEM74
transmembrane protein 74
chr6_+_131958441 0.016 NM_005021
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr4_+_186350543 0.015 NM_001114357
C4orf47
chromosome 4 open reading frame 47
chr19_+_38810461 0.015 NM_004823
KCNK6
potassium channel, subfamily K, member 6
chr2_+_68961912 0.015 NM_001007231
NM_001166277
ARHGAP25

Rho GTPase activating protein 25

chr7_-_23571443 0.015 NM_013293
TRA2A
transformer 2 alpha homolog (Drosophila)
chr10_+_1102295 0.014 WDR37
WD repeat domain 37
chr7_-_50633042 0.014 NM_001082971
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr3_-_52713728 0.014 NM_018165
NM_181042
PBRM1

polybromo 1

chr14_+_100531764 0.014 EVL
Enah/Vasp-like
chr5_-_35230822 0.014 NM_000949
PRLR
prolactin receptor
chr22_+_51176623 0.013 NM_001097
ACR
acrosin
chr3_-_194090459 0.013 NM_001135057
NM_130830
LRRC15

leucine rich repeat containing 15

chr6_-_152702329 0.013 SYNE1
spectrin repeat containing, nuclear envelope 1
chrX_-_153141398 0.013 NM_000425
NM_001143963
NM_024003
L1CAM


L1 cell adhesion molecule


chr9_-_15250113 0.013 NM_001168342
TTC39B
tetratricopeptide repeat domain 39B
chr20_-_33460558 0.013 NM_178026
GGT7
gamma-glutamyltransferase 7
chr19_+_8509859 0.013 HNRNPM
heterogeneous nuclear ribonucleoprotein M
chr15_-_42186274 0.013 NM_016642
SPTBN5
spectrin, beta, non-erythrocytic 5
chr4_+_88754120 0.013 NM_001184695
NM_001184696
NM_001184697
NM_020203
MEPE



matrix extracellular phosphoglycoprotein



chr19_+_8509875 0.013 HNRNPM
heterogeneous nuclear ribonucleoprotein M
chr10_-_91102430 0.012 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr3_-_33700480 0.012 CLASP2
cytoplasmic linker associated protein 2
chr9_-_34729463 0.012 NM_001141917
FAM205A
family with sequence similarity 205, member A
chr7_-_87856282 0.012 NM_198901
SRI
sorcin
chr17_-_3599359 0.012 P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr9_+_112403067 0.012 NM_001037293
PALM2
paralemmin 2
chr11_+_111783476 0.012 HSPB2-C11orf52
HSPB2
HSPB2-C11orf52 readthrough (non-protein coding)
heat shock 27kDa protein 2
chr5_-_58882274 0.012 NM_006203
PDE4D
phosphodiesterase 4D, cAMP-specific
chr12_-_111893857 0.012


chr2_+_27255823 0.012 TMEM214
transmembrane protein 214
chr3_-_9290592 0.012 SRGAP3
SLIT-ROBO Rho GTPase activating protein 3
chr19_+_38810540 0.011 KCNK6
potassium channel, subfamily K, member 6
chr10_-_7708805 0.011 NM_001001851
NM_030569
ITIH5

inter-alpha-trypsin inhibitor heavy chain family, member 5

chrX_-_119445306 0.011 NM_001104544
NM_001104545
NM_017938
FAM70A


family with sequence similarity 70, member A


chr14_+_29236882 0.011 FOXG1
forkhead box G1
chr14_-_94855120 0.011 NM_000295
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr2_+_39892637 0.011 NM_001167959
TMEM178
transmembrane protein 178
chr9_+_134305532 0.011


chr2_+_211458078 0.011 NM_001122634
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr14_+_105941061 0.011 NM_001312
CRIP2
cysteine-rich protein 2
chr7_+_26400503 0.011 NM_001199837
SNX10
sorting nexin 10
chr10_+_105005643 0.011 NM_001143909
LOC729020
rcRPE
chr1_+_16767218 0.011 NECAP2
NECAP endocytosis associated 2
chr14_+_74960442 0.010 NM_194279
ISCA2
iron-sulfur cluster assembly 2 homolog (S. cerevisiae)
chr11_-_6462129 0.010 NM_000613
HPX
hemopexin
chr18_-_55287856 0.010


chr3_-_170303774 0.010 NM_020949
SLC7A14
solute carrier family 7 (orphan transporter), member 14
chr14_+_78266419 0.010 NM_001142545
NM_020421
ADCK1

aarF domain containing kinase 1

chr14_-_94854910 0.010 SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr9_+_132388404 0.010 NM_014064
METTL11A
methyltransferase like 11A
chr1_+_203734283 0.010 NM_001136190
NM_017773
LAX1

lymphocyte transmembrane adaptor 1

chr11_+_6226797 0.010 NM_173525
C11orf42
chromosome 11 open reading frame 42
chrX_+_100474932 0.010 NM_001171184
NM_001939
DRP2

dystrophin related protein 2

chr9_+_124048869 0.010 GSN
gelsolin
chrX_+_70521627 0.010 NM_012278
ITGB1BP2
integrin beta 1 binding protein (melusin) 2
chr19_+_38810520 0.010 KCNK6
potassium channel, subfamily K, member 6
chr4_-_46125929 0.010 NM_173536
GABRG1
gamma-aminobutyric acid (GABA) A receptor, gamma 1
chr12_+_25205180 0.010 NM_001204126
NM_001204127
NM_006152
LRMP


lymphoid-restricted membrane protein


chr1_-_168698412 0.010 NM_001937
DPT
dermatopontin
chr5_-_54529424 0.010 NM_021147
CCNO
cyclin O

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.