Motif ID: GCUGGUG

Z-value: 0.800


Mature miRNA associated with seed GCUGGUG:

NamemiRBase Accession
hsa-miR-138 MIMAT0000430



Activity profile for motif GCUGGUG.

activity profile for motif GCUGGUG


Sorted Z-values histogram for motif GCUGGUG

Sorted Z-values for motif GCUGGUG



Network of associatons between targets according to the STRING database.



First level regulatory network of GCUGGUG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_47840058 0.326 NM_006587
CORIN
corin, serine peptidase
chr17_+_38465422 0.305 NM_000964
RARA
retinoic acid receptor, alpha
chr17_+_38474472 0.272 NM_001145301
NM_001145302
RARA

retinoic acid receptor, alpha

chr2_-_213403280 0.249 NM_001042599
NM_005235
ERBB4

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

chr20_+_10199455 0.241 NM_003081
NM_130811
SNAP25

synaptosomal-associated protein, 25kDa

chr3_-_46777918 0.220 NM_001205271
PRSS46
protease, serine, 46
chr8_-_41522724 0.205 NM_001142445
NM_020478
NM_020480
ANK1


ankyrin 1, erythrocytic


chr1_+_61547388 0.199 NM_001145512
NFIA
nuclear factor I/A
chr17_+_38498270 0.192 NM_001024809
RARA
retinoic acid receptor, alpha
chr20_+_33292117 0.189 NM_021202
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr11_+_58939539 0.184 NM_015177
DTX4
deltex homolog 4 (Drosophila)
chr13_-_67804432 0.176 NM_020403
NM_203487
PCDH9

protocadherin 9

chr8_-_20112691 0.174 NM_021020
LZTS1
leucine zipper, putative tumor suppressor 1
chr9_-_127905715 0.170 NM_001144877
NM_173690
SCAI

suppressor of cancer cell invasion

chr17_+_54911452 0.170 NM_003647
DGKE
diacylglycerol kinase, epsilon 64kDa
chr8_+_106331146 0.168 NM_012082
ZFPM2
zinc finger protein, multitype 2
chrX_+_102862833 0.167 NM_001006933
NM_032926
TCEAL3

transcription elongation factor A (SII)-like 3

chr16_-_57318574 0.165 NM_015993
PLLP
plasmolipin
chr1_-_23857711 0.165 NM_004091
E2F2
E2F transcription factor 2
chr17_+_18163836 0.163 NM_001144900
NM_139162
SMCR7

Smith-Magenis syndrome chromosome region, candidate 7

chr5_-_115910406 0.161 NM_020796
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr5_-_142815076 0.156 NM_001018074
NM_001018075
NM_001018077
NR3C1


nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)


chr6_+_64281910 0.156 NM_003463
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr1_+_61542928 0.152 NM_001145511
NFIA
nuclear factor I/A
chr19_+_41768368 0.150 NM_144732
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr20_+_42086468 0.150 NM_006275
SRSF6
serine/arginine-rich splicing factor 6
chr21_-_28339405 0.150 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr10_+_18948276 0.148 NM_178815
ARL5B
ADP-ribosylation factor-like 5B
chr22_+_39101806 0.147 NM_004286
GTPBP1
GTP binding protein 1
chr3_-_13008959 0.145 NM_014869
IQSEC1
IQ motif and Sec7 domain 1
chr6_+_39760772 0.144 NM_015345
DAAM2
dishevelled associated activator of morphogenesis 2
chr17_+_37617688 0.140 NM_015083
NM_016507
CDK12

cyclin-dependent kinase 12

chr10_+_80828776 0.139 NM_020338
ZMIZ1
zinc finger, MIZ-type containing 1
chr7_+_8008416 0.134 NM_138426
GLCCI1
glucocorticoid induced transcript 1
chr1_+_61547625 0.133 NM_001134673
NM_005595
NFIA

nuclear factor I/A

chr5_-_142783975 0.133 NM_001018076
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr1_+_36689996 0.127 NM_005119
THRAP3
thyroid hormone receptor associated protein 3
chr15_-_56035176 0.126 NM_173814
PRTG
protogenin
chr6_-_100911550 0.125 NM_005068
SIM1
single-minded homolog 1 (Drosophila)
chr4_-_42658883 0.125 NM_001105529
NM_006095
ATP8A1

ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1

chr16_-_87525317 0.124 NM_015144
ZCCHC14
zinc finger, CCHC domain containing 14
chr3_-_9291251 0.123 NM_001033117
NM_014850
SRGAP3

SLIT-ROBO Rho GTPase activating protein 3

chr3_-_13114547 0.123 NM_001134382
IQSEC1
IQ motif and Sec7 domain 1
chr5_-_142783225 0.119 NM_000176
NM_001020825
NM_001024094
NM_001204258
NM_001204259
NM_001204260
NM_001204261
NM_001204262
NM_001204263
NM_001204264
NM_001204265
NR3C1










nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)










chr11_-_115375065 0.118 NM_001098517
NM_014333
CADM1

cell adhesion molecule 1

chr3_+_156392204 0.118 NM_015508
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr16_-_29910340 0.115 NM_001114099
NM_001114100
NM_001243332
NM_001243333
NM_012410
NM_201575
SEZ6L2





seizure related 6 homolog (mouse)-like 2





chr6_-_39895317 0.114 NM_005943
MOCS1
molybdenum cofactor synthesis 1
chr20_+_56884749 0.113 NM_020673
RAB22A
RAB22A, member RAS oncogene family
chr5_+_167718485 0.113 NM_001161661
NM_001161662
NM_015238
WWC1


WW and C2 domain containing 1


chr18_+_67956136 0.112 NM_004232
SOCS6
suppressor of cytokine signaling 6
chr3_+_156392714 0.111 NM_001184717
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr16_+_69599868 0.111 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chr17_+_18164423 0.109 NM_148886
SMCR7
Smith-Magenis syndrome chromosome region, candidate 7
chr11_-_130184459 0.108 NM_014155
ZBTB44
zinc finger and BTB domain containing 44
chr14_+_60712469 0.108 NM_177952
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr14_+_66974124 0.107 NM_001024218
NM_020806
GPHN

gephyrin

chr6_-_30658740 0.105 NM_007243
NRM
nurim (nuclear envelope membrane protein)
chr3_+_156394452 0.105 NM_001184718
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr4_-_185570575 0.104 NM_004346
NM_032991
CASP3

caspase 3, apoptosis-related cysteine peptidase

chr4_+_87856152 0.104 NM_001166693
AFF1
AF4/FMR2 family, member 1
chr2_+_7057471 0.102 NM_014746
RNF144A
ring finger protein 144A
chr13_+_77566043 0.101 NM_006493
CLN5
ceroid-lipofuscinosis, neuronal 5
chr18_-_12884140 0.101 NM_001207013
NM_002828
NM_080422
NM_080423
PTPN2



protein tyrosine phosphatase, non-receptor type 2



chr9_+_118916069 0.100 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr17_-_37557851 0.100 NM_001184906
NM_032875
FBXL20

F-box and leucine-rich repeat protein 20

chr6_-_39902140 0.099 NM_001075098
MOCS1
molybdenum cofactor synthesis 1
chr20_-_46415277 0.098 NM_001161841
NM_198596
SULF2

sulfatase 2

chr5_+_38445577 0.098 NM_182801
EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr11_-_57417247 0.097 NM_145008
YPEL4
yippee-like 4 (Drosophila)
chr1_+_44173217 0.097 NM_006279
NM_174963
NM_174964
NM_174965
NM_174966
NM_174967
NM_174968
NM_174969
NM_174970
NM_174971
ST3GAL3









ST3 beta-galactoside alpha-2,3-sialyltransferase 3









chr9_-_14398981 0.096 NM_001190738
NFIB
nuclear factor I/B
chr12_+_132195632 0.095 NM_004592
SFSWAP
splicing factor, suppressor of white-apricot homolog (Drosophila)
chr19_+_41770057 0.094 NM_007040
HNRNPUL1
heterogeneous nuclear ribonucleoprotein U-like 1
chr1_-_173176314 0.094 NM_003326
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr9_-_14314036 0.093 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr20_+_36661849 0.092 NM_021215
RPRD1B
regulation of nuclear pre-mRNA domain containing 1B
chrX_+_9432980 0.092 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr6_+_41514133 0.092 NM_001012426
NM_001012427
NM_138457
FOXP4


forkhead box P4


chr3_+_42695175 0.092 NM_145166
ZBTB47
zinc finger and BTB domain containing 47
chrX_+_9431314 0.091 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr3_+_50284325 0.090 NM_001166425
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr2_+_208394615 0.090 NM_004379
NM_134442
CREB1

cAMP responsive element binding protein 1

chr3_-_33481877 0.090 NM_001128161
UBP1
upstream binding protein 1 (LBP-1a)
chr3_-_53381533 0.089 NM_018403
DCP1A
DCP1 decapping enzyme homolog A (S. cerevisiae)
chr12_-_110318178 0.088 NM_016433
GLTP
glycolipid transfer protein
chr20_-_30795346 0.086 NM_002657
PLAGL2
pleiomorphic adenoma gene-like 2
chr1_+_33116748 0.086 NM_001135255
NM_005610
NM_001135256
RBBP4


retinoblastoma binding protein 4


chr4_+_87928083 0.086 NM_005935
AFF1
AF4/FMR2 family, member 1
chr11_-_65381641 0.085 NM_002419
MAP3K11
mitogen-activated protein kinase kinase kinase 11
chr22_+_41697452 0.085 NM_017590
ZC3H7B
zinc finger CCCH-type containing 7B
chr1_+_204042191 0.085 NM_005686
SOX13
SRY (sex determining region Y)-box 13
chr12_-_54653369 0.085 NM_001127321
CBX5
chromobox homolog 5
chr4_+_77870864 0.084 NM_018243
SEPT11
septin 11
chr12_-_54653317 0.083 NM_001127322
CBX5
chromobox homolog 5
chr7_-_72936592 0.083 NM_032408
BAZ1B
bromodomain adjacent to zinc finger domain, 1B
chr22_-_43583132 0.083 NM_015140
TTLL12
tubulin tyrosine ligase-like family, member 12
chr11_-_77348758 0.081 NM_001293
CLNS1A
chloride channel, nucleotide-sensitive, 1A
chr9_-_36400212 0.081 NM_022781
NM_194329
RNF38

ring finger protein 38

chr12_+_20522178 0.081 NM_000921
PDE3A
phosphodiesterase 3A, cGMP-inhibited
chr16_+_50582193 0.080 NM_033119
NKD1
naked cuticle homolog 1 (Drosophila)
chrX_+_21857655 0.080 NM_015884
MBTPS2
membrane-bound transcription factor peptidase, site 2
chr13_-_72441312 0.079 NM_004392
NM_080759
NM_080760
DACH1


dachshund homolog 1 (Drosophila)


chrX_+_152599544 0.079 NM_001080485
ZNF275
zinc finger protein 275
chr2_+_70142152 0.078 NM_001202513
NM_001202514
NM_002357
MXD1


MAX dimerization protein 1


chr10_+_72163860 0.078 NM_004096
EIF4EBP2
eukaryotic translation initiation factor 4E binding protein 2
chr3_-_33481862 0.078 NM_001128160
NM_014517
UBP1

upstream binding protein 1 (LBP-1a)

chr2_-_100758970 0.078 NM_002285
AFF3
AF4/FMR2 family, member 3
chr3_+_50273645 0.078 NM_002070
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr6_-_119252887 0.077 NM_017696
MCM9
minichromosome maintenance complex component 9
chr14_+_62162042 0.076 NM_001530
NM_181054
HIF1A

hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)

chr19_+_3224700 0.075 NM_021938
NM_001172673
CELF5

CUGBP, Elav-like family member 5

chr2_-_100721792 0.075 NM_001025108
AFF3
AF4/FMR2 family, member 3
chr3_-_56809594 0.075 NM_001128616
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr8_-_57906423 0.074 NM_017813
IMPAD1
inositol monophosphatase domain containing 1
chr8_-_41655139 0.074 NM_000037
NM_020475
NM_020476
NM_020477
ANK1



ankyrin 1, erythrocytic



chr3_+_140950671 0.073 NM_001037172
NM_152282
ACPL2

acid phosphatase-like 2

chr8_+_37654395 0.073 NM_032777
GPR124
G protein-coupled receptor 124
chr13_-_101327102 0.072 NM_001079669
NM_032813
TMTC4

transmembrane and tetratricopeptide repeat containing 4

chr19_+_19496629 0.072 NM_017660
GATAD2A
GATA zinc finger domain containing 2A
chr20_-_46414636 0.071 NM_018837
SULF2
sulfatase 2
chr12_+_69864065 0.071 NM_001042555
NM_006654
FRS2

fibroblast growth factor receptor substrate 2

chr2_+_219263060 0.070 NM_001206878
CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr11_-_75062650 0.070 NM_004041
NM_020251
ARRB1

arrestin, beta 1

chr3_-_133748828 0.070 NM_005630
SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr1_-_31712733 0.069 NM_024522
NKAIN1
Na+/K+ transporting ATPase interacting 1
chr6_+_35310317 0.069 NM_001171818
NM_001171819
NM_001171820
NM_006238
NM_177435
PPARD




peroxisome proliferator-activated receptor delta




chr22_+_31090792 0.068 NM_030758
OSBP2
oxysterol binding protein 2
chr12_-_48499415 0.068 NM_014554
SENP1
SUMO1/sentrin specific peptidase 1
chr7_-_92465929 0.068 NM_001145306
CDK6
cyclin-dependent kinase 6
chr3_-_57113292 0.068 NM_001128615
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr7_-_152133071 0.067 NM_170606
MLL3
myeloid/lymphoid or mixed-lineage leukemia 3
chr5_-_56247915 0.066 NM_152622
MIER3
mesoderm induction early response 1, family member 3
chr5_-_114880536 0.065 NM_020177
FEM1C
fem-1 homolog c (C. elegans)
chr1_-_27930101 0.064 NM_001029882
AHDC1
AT hook, DNA binding motif, containing 1
chr11_-_128894008 0.064 NM_014715
ARHGAP32
Rho GTPase activating protein 32
chr1_+_26438267 0.064 NM_001243533
NM_152835
PDIK1L

PDLIM1 interacting kinase 1 like

chr8_-_81787015 0.064 NM_001033723
ZNF704
zinc finger protein 704
chr5_+_156693051 0.063 NM_001037333
NM_001037332
CYFIP2

cytoplasmic FMR1 interacting protein 2

chr6_+_39760148 0.063 NM_001201427
DAAM2
dishevelled associated activator of morphogenesis 2
chr2_+_86947387 0.063 NM_022780
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr6_+_21593963 0.063 NM_003107
SOX4
SRY (sex determining region Y)-box 4
chr16_+_58549382 0.062 NM_001160305
NM_024860
SETD6

SET domain containing 6

chr5_+_179125796 0.062 NM_001024649
NM_001746
CANX

calnexin

chr1_-_153895450 0.061 NM_020699
GATAD2B
GATA zinc finger domain containing 2B
chr12_+_26126687 0.061 NM_001164747
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr3_+_16306666 0.061 NM_138381
OXNAD1
oxidoreductase NAD-binding domain containing 1
chr20_+_36149606 0.061 NM_005386
NM_181689
NNAT

neuronatin

chr12_+_26205490 0.061 NM_001164746
RASSF8
Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
chr22_+_35653444 0.060 NM_001003681
HMGXB4
HMG box domain containing 4
chr4_-_140060601 0.059 NM_201999
ELF2
E74-like factor 2 (ets domain transcription factor)
chr15_-_30114536 0.059 NM_003257
NM_175610
TJP1

tight junction protein 1 (zona occludens 1)

chr17_+_47074749 0.059 NM_001160423
NM_006546
IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1

chr1_+_40840304 0.059 NM_001198978
SMAP2
small ArfGAP2
chr2_-_85788644 0.059 NM_000821
NM_001142269
GGCX

gamma-glutamyl carboxylase

chr19_-_14316980 0.058 NM_001008701
NM_014921
LPHN1

latrophilin 1

chr1_+_36348795 0.058 NM_012199
EIF2C1
eukaryotic translation initiation factor 2C, 1
chr6_+_107811272 0.058 NM_018013
SOBP
sine oculis binding protein homolog (Drosophila)
chr12_+_32654976 0.058 NM_139241
FGD4
FYVE, RhoGEF and PH domain containing 4
chr3_-_56835829 0.057 NM_019555
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr18_-_53255734 0.057 NM_001083962
NM_001243230
NM_003199
TCF4


transcription factor 4


chr4_-_78740508 0.056 NM_144571
CNOT6L
CCR4-NOT transcription complex, subunit 6-like
chr11_+_63655986 0.055 NM_017490
MARK2
MAP/microtubule affinity-regulating kinase 2
chr2_+_148602569 0.055 NM_001616
ACVR2A
activin A receptor, type IIA
chr1_+_40859016 0.054 NM_001198979
SMAP2
small ArfGAP2
chr1_-_109935869 0.054 NM_001205228
SORT1
sortilin 1
chr7_-_92463211 0.054 NM_001259
CDK6
cyclin-dependent kinase 6
chr19_-_14228362 0.054 NM_002730
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr19_-_14224979 0.053 NM_207518
PRKACA
protein kinase, cAMP-dependent, catalytic, alpha
chr20_-_4990913 0.052 NM_203327
SLC23A2
solute carrier family 23 (nucleobase transporters), member 2
chr3_+_23986735 0.052 NM_005126
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr3_-_141944441 0.051 NM_001039547
GK5
glycerol kinase 5 (putative)
chr2_-_153573858 0.051 NM_017892
PRPF40A
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae)
chr5_-_73937248 0.051 NM_003633
ENC1
ectodermal-neural cortex 1 (with BTB-like domain)
chr9_+_706744 0.051 NM_153186
KANK1
KN motif and ankyrin repeat domains 1
chr9_-_36401149 0.051 NM_194330
RNF38
ring finger protein 38
chr11_-_85376159 0.050 NM_001039618
CREBZF
CREB/ATF bZIP transcription factor
chrX_-_63425484 0.050 NM_152424
FAM123B
family with sequence similarity 123B
chr18_-_57026465 0.050 NM_005570
LMAN1
lectin, mannose-binding, 1
chr2_+_219264477 0.049 NM_021198
NM_182642
CTDSP1

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1

chr11_+_107879407 0.049 NM_003478
CUL5
cullin 5
chr11_-_67980699 0.049 NM_016028
NM_017635
SUV420H1

suppressor of variegation 4-20 homolog 1 (Drosophila)

chr10_+_73723992 0.048 NM_004273
CHST3
carbohydrate (chondroitin 6) sulfotransferase 3
chr12_+_57984914 0.047 NM_001146258
NM_001146259
NM_001146260
NM_024779
PIP4K2C



phosphatidylinositol-5-phosphate 4-kinase, type II, gamma



chr5_+_66124603 0.047 NM_015183
MAST4
microtubule associated serine/threonine kinase family member 4
chr13_-_52585472 0.047 NM_000053
NM_001005918
NM_001243182
ATP7B


ATPase, Cu++ transporting, beta polypeptide


chr11_-_70507911 0.046 NM_133266
SHANK2
SH3 and multiple ankyrin repeat domains 2
chr5_-_74162614 0.046 NM_015566
FAM169A
family with sequence similarity 169, member A
chr6_+_114178516 0.045 NM_002356
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr2_+_24807345 0.045 NM_003743
NM_147223
NM_147233
NCOA1


nuclear receptor coactivator 1


chr1_-_109940497 0.045 NM_002959
SORT1
sortilin 1
chr13_+_28712379 0.045 NM_175854
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr3_+_23987514 0.044 NM_001145425
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr18_+_59854514 0.044 NM_020854
KIAA1468
KIAA1468
chr5_+_38403633 0.044 NM_182798
EGFLAM
EGF-like, fibronectin type III and laminin G domains
chr19_+_45909466 0.044 NM_012099
CD3EAP
CD3e molecule, epsilon associated protein
chr1_-_32385258 0.044 NM_001195100
NM_001195101
PTP4A2

protein tyrosine phosphatase type IVA, member 2

chr19_-_8070468 0.044 NM_001419
ELAVL1
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R)
chr20_-_4982133 0.044 NM_005116
SLC23A2
solute carrier family 23 (nucleobase transporters), member 2
chr12_-_120806893 0.043 NM_002442
MSI1
musashi homolog 1 (Drosophila)

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.