Motif ID: GFI1B.p2

Z-value: 0.393


Transcription factors associated with GFI1B.p2:

Gene SymbolEntrez IDGene Name
GFI1B 8328 growth factor independent 1B transcription repressor



Activity profile for motif GFI1B.p2.

activity profile for motif GFI1B.p2


Sorted Z-values histogram for motif GFI1B.p2

Sorted Z-values for motif GFI1B.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1B.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_26217145 0.290 NM_021052
HIST1H2AE
histone cluster 1, H2ae
chr2_+_177028804 0.178 NM_006898
HOXD3
homeobox D3
chr7_-_16505292 0.174 NM_015464
SOSTDC1
sclerostin domain containing 1
chr6_+_26020677 0.159 NM_003529
HIST1H3A
histone cluster 1, H3a
chr3_-_133748828 0.156 NM_005630
SLCO2A1
solute carrier organic anion transporter family, member 2A1
chr11_+_112046207 0.146 NM_031938
BCO2
beta-carotene oxygenase 2
chr4_+_110749149 0.138 NM_006583
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr11_+_111789600 0.130 NM_080659
C11orf52
chromosome 11 open reading frame 52
chr2_-_157189040 0.112 NM_006186
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr1_-_198906536 0.110 LOC100131234
familial acute myelogenous leukemia related factor
chr7_+_137761177 0.105 NM_001190906
NM_001190907
NM_005989
AKR1D1


aldo-keto reductase family 1, member D1 (delta 4-3-ketosteroid-5-beta-reductase)


chr1_-_7973286 0.096 UTS2
urotensin 2
chr1_+_168250277 0.096 NM_005149
TBX19
T-box 19
chr6_-_26216871 0.095 NM_003518
HIST1H2BG
NCALD
histone cluster 1, H2bg
neurocalcin delta
chr17_-_56494930 0.094 NM_017763
RNF43
ring finger protein 43
chr6_+_12290528 0.087 NM_001168319
NM_001955
EDN1

endothelin 1

chr3_-_112359962 0.085 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chr14_+_69951396 0.085 NM_001161498
PLEKHD1
pleckstrin homology domain containing, family D (with coiled-coil domains) member 1
chr3_+_141105283 0.080


chr8_-_124544376 0.080 NM_148177
FBXO32
F-box protein 32
chr4_+_86749045 0.078 ARHGAP24
Rho GTPase activating protein 24
chr6_-_134498973 0.078 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr17_-_56494889 0.075 RNF43
ring finger protein 43
chr18_-_24445652 0.073 NM_001650
AQP4
aquaporin 4
chrX_-_10588458 0.072 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr12_+_18891040 0.072 NM_033328
CAPZA3
capping protein (actin filament) muscle Z-line, alpha 3
chr1_+_84647342 0.072 NM_001242862
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr3_+_188889762 0.071 NM_198485
TPRG1
tumor protein p63 regulated 1
chr17_+_1619816 0.069 NM_001163673
NM_152348
WDR81

WD repeat domain 81

chr21_+_30517897 0.068 C21orf7
chromosome 21 open reading frame 7
chr7_+_55433140 0.066 NM_018697
LANCL2
LanC lantibiotic synthetase component C-like 2 (bacterial)
chr21_-_27512668 0.066 NM_001136016
APP
amyloid beta (A4) precursor protein
chr7_-_92855780 0.059 NM_001039372
HEPACAM2
HEPACAM family member 2
chr3_+_186358148 0.058 NM_014375
FETUB
fetuin B
chr2_-_190044330 0.058 NM_000393
COL5A2
collagen, type V, alpha 2
chr2_-_134179325 0.058 NCKAP5
NCK-associated protein 5
chr4_-_40936640 0.056 APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr3_-_112359863 0.052 CCDC80
coiled-coil domain containing 80
chr1_+_164528914 0.052 PBX1
pre-B-cell leukemia homeobox 1
chr5_-_146460991 0.052 NM_181677
NM_181678
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chr8_+_27179918 0.052 NM_004103
PTK2B
PTK2B protein tyrosine kinase 2 beta
chr19_-_13227212 0.052 NM_001142554
NM_017722
NM_001136035
TRMT1


TRM1 tRNA methyltransferase 1 homolog (S. cerevisiae)


chr6_-_31648140 0.052 NM_025262
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr5_+_109025085 0.051


chr6_-_144329254 0.051 PLAGL1
pleiomorphic adenoma gene-like 1
chrX_+_17393806 0.051 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr1_-_17308072 0.049 NM_001135247
NM_017459
MFAP2

microfibrillar-associated protein 2

chr17_+_41003360 0.048


chr4_-_72649734 0.046 NM_000583
GC
group-specific component (vitamin D binding protein)
chr6_+_31707724 0.046 NM_002441
NM_025259
NM_172165
NM_172166
MSH5-C6orf26
MSH5



MSH5-C6orf26 readthrough (non-protein coding)
mutS homolog 5 (E. coli)



chr7_-_50633042 0.046 NM_001082971
DDC
dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr1_-_190446701 0.045 NM_199051
FAM5C
family with sequence similarity 5, member C
chr4_-_1722978 0.045 NM_001127266
NM_138385
TMEM129

transmembrane protein 129

chr11_+_5710926 0.045 TRIM22
tripartite motif containing 22
chr16_+_68279206 0.042 NM_012320
PLA2G15
phospholipase A2, group XV
chr4_-_186877413 0.040 SORBS2
sorbin and SH3 domain containing 2
chr4_+_110772485 0.040 NM_198506
LRIT3
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3
chr1_-_21501229 0.040 NM_001198803
EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chrX_+_119738542 0.038 NM_001137554
MCTS1
malignant T cell amplified sequence 1
chr6_-_26108320 0.038 NM_005323
HIST1H1T
histone cluster 1, H1t
chr4_-_155511838 0.038 NM_000508
NM_021871
FGA

fibrinogen alpha chain

chr17_-_40729649 0.037 NM_013290
NM_016556
PSMC3IP

PSMC3 interacting protein

chr22_+_40573879 0.037 NM_001162501
NM_015088
TNRC6B

trinucleotide repeat containing 6B

chr6_+_26087447 0.036 NM_000410
NM_139003
NM_139004
NM_139006
NM_139007
NM_139008
NM_139009
NM_139010
NM_139011
HFE








hemochromatosis








chr4_+_15471488 0.036 NM_001080522
NM_001164720
NM_020785
CC2D2A


coiled-coil and C2 domain containing 2A


chr1_+_50575465 0.036 ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr17_-_79905108 0.035 NM_001145113
MYADML2
myeloid-associated differentiation marker-like 2
chr9_+_97521930 0.035 NM_001193329
C9orf3
chromosome 9 open reading frame 3
chrX_-_33146543 0.035 NM_004010
NM_004009
DMD

dystrophin

chr16_+_68279297 0.035 PLA2G15
phospholipase A2, group XV
chr5_+_109025046 0.034 MAN2A1
mannosidase, alpha, class 2A, member 1
chr3_-_187454247 0.034 NM_001130845
BCL6
B-cell CLL/lymphoma 6
chr17_+_38279468 0.034 MSL1
male-specific lethal 1 homolog (Drosophila)
chrX_+_47967376 0.034 NM_001205103
LOC100509575
putative protein SSX6-like
chrX_-_21676416 0.033 NM_153270
KLHL34
kelch-like 34 (Drosophila)
chr19_+_46498338 0.033 NM_001080402
CCDC61
coiled-coil domain containing 61
chr1_+_156254069 0.032 NM_032323
TMEM79
transmembrane protein 79
chr4_+_88720701 0.032 NM_004967
IBSP
integrin-binding sialoprotein
chr7_-_113559048 0.032 NM_002711
PPP1R3A
protein phosphatase 1, regulatory subunit 3A
chr22_+_44395090 0.032 NM_001003828
PARVB
parvin, beta
chr19_-_14247400 0.031 NM_018154
ASF1B
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr1_-_33502452 0.031 AK2
adenylate kinase 2
chr5_-_88119604 0.031 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr2_-_165424993 0.031 GRB14
growth factor receptor-bound protein 14
chr1_+_192605267 0.031 NM_002927
NM_144766
RGS13

regulator of G-protein signaling 13

chr4_+_1283662 0.030 NM_001017405
NM_005882
MAEA

macrophage erythroblast attacher

chr12_-_56756526 0.030 NM_001638
APOF
apolipoprotein F
chr15_+_54305100 0.030 NM_001080534
UNC13C
unc-13 homolog C (C. elegans)
chr12_-_112630525 0.029 C12orf51
chromosome 12 open reading frame 51
chr17_-_1619473 0.028 MIR22HG
MIR22 host gene (non-protein coding)
chr1_-_149900143 0.028 NM_005850
SF3B4
splicing factor 3b, subunit 4, 49kDa
chr9_+_96233420 0.028 FAM120A
family with sequence similarity 120A
chr3_+_158991090 0.028 SCHIP1
schwannomin interacting protein 1
chr5_-_88179278 0.028 NM_001193350
NM_002397
MEF2C

myocyte enhancer factor 2C

chrX_+_77154956 0.028 NM_001866
COX7B
cytochrome c oxidase subunit VIIb
chr6_+_27925018 0.027 NM_012367
OR2B6
olfactory receptor, family 2, subfamily B, member 6
chr9_+_2717525 0.027 NM_133497
KCNV2
potassium channel, subfamily V, member 2
chr16_+_83986826 0.027 NM_182981
OSGIN1
oxidative stress induced growth inhibitor 1
chr17_+_20771745 0.027


chr4_-_186733372 0.026 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr12_+_50017340 0.026 NM_012272
PRPF40B
PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)
chr2_+_103378489 0.026 NM_144632
TMEM182
transmembrane protein 182
chr5_+_140792507 0.026 NM_018913
NM_032090
PCDHGA10

protocadherin gamma subfamily A, 10

chr3_-_9291251 0.026 NM_001033117
NM_014850
SRGAP3

SLIT-ROBO Rho GTPase activating protein 3

chr5_-_59995897 0.026 DEPDC1B
DEP domain containing 1B
chr5_+_42756919 0.026 NM_001134848
CCDC152
coiled-coil domain containing 152
chr17_+_41003184 0.026 NM_003734
AOC3
amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr21_-_47604360 0.025 NM_001142854
NM_032261
C21orf56

chromosome 21 open reading frame 56

chr14_-_73360792 0.025 NM_012074
DPF3
D4, zinc and double PHD fingers, family 3
chr3_-_112359547 0.025 CCDC80
coiled-coil domain containing 80
chr6_-_167040700 0.025 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chrX_+_17393877 0.025 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr1_+_66797775 0.024 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chr11_+_57529233 0.024 NM_001085458
NM_001085459
NM_001085460
NM_001085461
NM_001085462
NM_001085463
NM_001085464
NM_001085465
NM_001085466
NM_001085467
NM_001085468
NM_001085469
NM_001206883
NM_001206884
NM_001206885
NM_001206886
NM_001206887
NM_001206888
NM_001206889
NM_001206890
NM_001206891
NM_001331
CTNND1





















catenin (cadherin-associated protein), delta 1





















chr10_+_69644341 0.024 NM_012238
SIRT1
sirtuin 1
chr11_-_84634437 0.024 NM_001364
DLG2
discs, large homolog 2 (Drosophila)
chr17_+_41052813 0.024 NM_000151
G6PC
glucose-6-phosphatase, catalytic subunit
chr21_-_46237882 0.024 SUMO3
SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)
chr19_+_49999682 0.024 RPS11
ribosomal protein S11
chr1_+_57320442 0.023 NM_000562
C8A
complement component 8, alpha polypeptide
chr19_-_12476446 0.023 NM_030824
ZNF442
zinc finger protein 442
chr3_+_48507209 0.023 NM_016381
NM_033629
TREX1

three prime repair exonuclease 1

chr6_+_99282579 0.023 NM_005604
POU3F2
POU class 3 homeobox 2
chr8_+_67783736 0.023 NM_001136160
C8orf45
chromosome 8 open reading frame 45
chr5_-_111312522 0.023 NM_001142474
NM_001142475
C5orf13

chromosome 5 open reading frame 13

chr12_-_56843154 0.023 NM_003920
TIMELESS
timeless homolog (Drosophila)
chr3_+_158991035 0.023 NM_001197107
NM_001197108
NM_014575
SCHIP1


schwannomin interacting protein 1


chrX_+_49832214 0.023 NM_000084
CLCN5
chloride channel 5
chr2_+_62900985 0.022 NM_001142615
EHBP1
EH domain binding protein 1
chr21_-_35899046 0.022 NM_203418
RCAN1
regulator of calcineurin 1
chr20_-_39317875 0.022 NM_005461
MAFB
v-maf musculoaponeurotic fibrosarcoma oncogene homolog B (avian)
chr15_+_76629101 0.022 NM_145805
ISL2
ISL LIM homeobox 2
chr5_-_111091947 0.022 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr5_-_37184945 0.022 C5orf42
chromosome 5 open reading frame 42
chr3_+_113557679 0.021 NM_017577
GRAMD1C
GRAM domain containing 1C
chr19_+_36545848 0.021 WDR62
WD repeat domain 62
chr15_+_100173182 0.021 NM_001130928
MEF2A
myocyte enhancer factor 2A
chrX_+_113818550 0.021 NM_000868
HTR2C
5-hydroxytryptamine (serotonin) receptor 2C
chr6_+_53883713 0.021 NM_138569
MLIP
muscular LMNA-interacting protein
chr11_+_112047088 0.021 NM_001037290
BCO2
beta-carotene oxygenase 2
chr1_+_24122327 0.021


chr11_-_62494785 0.021 NM_001079559
HNRNPUL2-BSCL2
HNRNPUL2
HNRNPUL2-BSCL2 readthrough
heterogeneous nuclear ribonucleoprotein U-like 2
chr1_+_210001399 0.020 DIEXF
digestive organ expansion factor homolog (zebrafish)
chr19_+_14640406 0.020 TECR
trans-2,3-enoyl-CoA reductase
chr4_-_100212085 0.020 NM_000667
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr11_-_71746966 0.020


chr22_+_19467467 0.020 CDC45
cell division cycle 45 homolog (S. cerevisiae)
chr3_+_169492051 0.020 NM_001185119
MYNN
myoneurin
chr19_+_16308664 0.020 NM_001130524
NM_032493
AP1M1

adaptor-related protein complex 1, mu 1 subunit

chr18_+_32073245 0.020 NM_001198945
NM_001392
NM_032975
NM_032979
DTNA



dystrobrevin, alpha



chrX_+_17393349 0.020 NHS
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr17_+_7461591 0.019 NM_001198622
NM_001198623
NM_001198624
NM_003808
NM_172087
NM_172088
TNFSF13





tumor necrosis factor (ligand) superfamily, member 13





chr12_+_85430098 0.019 NM_001079910
LRRIQ1
leucine-rich repeats and IQ motif containing 1
chr6_+_43738394 0.019 VEGFA
vascular endothelial growth factor A
chr19_-_50464306 0.019 NM_001135163
NM_052884
SIGLEC11

sialic acid binding Ig-like lectin 11

chr14_+_29236171 0.019 NM_005249
FOXG1
forkhead box G1
chr19_-_14530129 0.019 DDX39A
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A
chr19_+_14640413 0.019 TECR
trans-2,3-enoyl-CoA reductase
chr14_-_94759556 0.019 SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr3_-_112359660 0.019 CCDC80
coiled-coil domain containing 80
chr4_+_6271558 0.019 NM_001145853
NM_006005
WFS1

Wolfram syndrome 1 (wolframin)

chr3_-_187452669 0.019 NM_001134738
BCL6
B-cell CLL/lymphoma 6
chr21_-_47704166 0.018 MCM3AP
minichromosome maintenance complex component 3 associated protein
chr2_+_219472487 0.018 NM_032726
PLCD4
phospholipase C, delta 4
chr17_-_7218665 0.018 GPS2
G protein pathway suppressor 2
chr5_-_146833150 0.018 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr1_+_43291230 0.018 NM_018538
ERMAP
erythroblast membrane-associated protein (Scianna blood group)
chr1_+_220960038 0.018 NM_022746
MARC1
mitochondrial amidoxime reducing component 1
chr9_-_116840551 0.018 AMBP
alpha-1-microglobulin/bikunin precursor
chr19_+_49999633 0.018 NM_001015
RPS11
ribosomal protein S11
chr1_-_177939049 0.018 NM_033127
SEC16B
SEC16 homolog B (S. cerevisiae)
chr6_-_24358279 0.018 NM_016356
DCDC2
doublecortin domain containing 2
chr4_+_6271588 0.018 WFS1
Wolfram syndrome 1 (wolframin)
chr1_-_179112178 0.017 NM_001136000
NM_001168239
NM_005158
ABL2


v-abl Abelson murine leukemia viral oncogene homolog 2


chr14_-_94759594 0.017 NM_001100607
SERPINA10
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr7_+_66093929 0.017 KCTD7
potassium channel tetramerisation domain containing 7
chr18_+_33234532 0.017 NM_020474
GALNT1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)
chr17_-_3496122 0.017 NM_080706
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr7_+_134832765 0.017 NM_018295
TMEM140
transmembrane protein 140
chr8_+_67782983 0.017 NM_001136161
NM_173518
C8orf45

chromosome 8 open reading frame 45

chr5_+_66124603 0.017 NM_015183
MAST4
microtubule associated serine/threonine kinase family member 4
chr1_+_210001267 0.017 NM_014388
DIEXF
digestive organ expansion factor homolog (zebrafish)
chr19_+_49999687 0.017 RPS11
ribosomal protein S11
chr18_-_24722757 0.017 NM_001243848
CHST9
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr1_+_84630575 0.017 NM_001242860
NM_001242861
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr19_+_18303989 0.017 NM_032683
MPV17L2
MPV17 mitochondrial membrane protein-like 2
chr18_-_47806361 0.016 NM_001204151
MBD1
methyl-CpG binding domain protein 1
chr6_+_152126807 0.016 NM_001122741
ESR1
estrogen receptor 1
chr11_-_62494927 0.016 HNRNPUL2
heterogeneous nuclear ribonucleoprotein U-like 2
chr3_-_190040192 0.016 NM_021101
CLDN1
claudin 1
chr12_-_24102563 0.016 NM_006940
SOX5
SRY (sex determining region Y)-box 5
chr16_-_70323343 0.016 AARS
alanyl-tRNA synthetase
chr16_+_2807490 0.016


chr1_+_118472346 0.016 WDR3
WD repeat domain 3
chr11_+_66233797 0.016 NM_001243135
PELI3
pellino homolog 3 (Drosophila)
chr1_+_46379258 0.015 MAST2
microtubule associated serine/threonine kinase 2
chrX_-_53024642 0.015 NM_001242489
NM_001242490
NM_001242492
NM_001242493
NM_001242494
NM_001242495
NM_001242496
NM_001242497
NM_014138
FAM156A








family with sequence similarity 156, member A








chr17_-_3499124 0.015 NM_080705
TRPV1
transient receptor potential cation channel, subfamily V, member 1
chr4_+_183245136 0.015 NM_001080477
ODZ3
odz, odd Oz/ten-m homolog 3 (Drosophila)
chrX_-_10645726 0.015 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.