Motif ID: GUCAGUU

Z-value: 0.709


Mature miRNA associated with seed GUCAGUU:

NamemiRBase Accession
hsa-miR-223 MIMAT0000280



Activity profile for motif GUCAGUU.

activity profile for motif GUCAGUU


Sorted Z-values histogram for motif GUCAGUU

Sorted Z-values for motif GUCAGUU



Network of associatons between targets according to the STRING database.



First level regulatory network of GUCAGUU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_175351755 0.185 NM_001033045
NM_152529
GPR155

G protein-coupled receptor 155

chrX_+_77166178 0.155 NM_000052
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr12_+_56732658 0.114 NM_016584
IL23A
interleukin 23, alpha subunit p19
chr8_-_74791098 0.112 NM_001001481
NM_018299
UBE2W

ubiquitin-conjugating enzyme E2W (putative)

chr5_+_71403040 0.112 NM_005909
MAP1B
microtubule-associated protein 1B
chr3_-_185270258 0.107 NM_139248
LIPH
lipase, member H
chr4_+_85504056 0.104 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr17_+_56833231 0.104 NM_014906
PPM1E
protein phosphatase, Mg2+/Mn2+ dependent, 1E
chr8_-_67579446 0.103 NM_025054
VCPIP1
valosin containing protein (p97)/p47 complex interacting protein 1
chr22_-_30642683 0.098 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr4_-_153303663 0.095 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr3_-_196230365 0.093 NM_152617
RNF168
ring finger protein 168
chr10_+_74033676 0.087 NM_019058
DDIT4
DNA-damage-inducible transcript 4
chr2_-_166060552 0.087 NM_001081676
NM_001081677
NM_006922
SCN3A


sodium channel, voltage-gated, type III, alpha subunit


chr11_-_34535302 0.083 NM_001243080
NM_001422
ELF5

E74-like factor 5 (ets domain transcription factor)

chr4_+_166248816 0.082 NM_001017369
NM_006745
MSMO1

methylsterol monooxygenase 1

chr10_+_104503724 0.078 NM_001083913
C10orf26
chromosome 10 open reading frame 26
chr15_+_71433787 0.075 NM_024817
THSD4
thrombospondin, type I, domain containing 4
chr3_-_71803923 0.075 NM_173359
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr3_-_71774407 0.074 NM_001134651
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chrX_-_13956644 0.073 NM_001001994
GPM6B
glycoprotein M6B
chr4_-_109089444 0.073 NM_001130713
NM_001130714
NM_016269
LEF1


lymphoid enhancer-binding factor 1


chr12_-_15374290 0.073 NM_001190726
NM_032918
RERG

RAS-like, estrogen-regulated, growth inhibitor

chrX_+_100805415 0.073 NM_016608
ARMCX1
armadillo repeat containing, X-linked 1
chr6_+_108881010 0.072 NM_201559
FOXO3
forkhead box O3
chr8_-_105601234 0.072 NM_001135703
NM_013437
LRP12

low density lipoprotein receptor-related protein 12

chr3_+_11313975 0.071 NM_001136031
NM_001144912
NM_006395
ATG7


ATG7 autophagy related 7 homolog (S. cerevisiae)


chr10_-_94050799 0.071 NM_014912
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr6_+_139456240 0.071 NM_016217
HECA
headcase homolog (Drosophila)
chrX_+_135278912 0.071 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr16_+_50059092 0.069 NM_153261
TMEM188
transmembrane protein 188
chrX_+_135229536 0.068 NM_001159702
NM_001159703
NM_001449
FHL1


four and a half LIM domains 1


chr3_-_71803513 0.067 NM_001134649
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr12_+_50497790 0.067 NM_005276
GPD1
glycerol-3-phosphate dehydrogenase 1 (soluble)
chr6_+_108882068 0.066 NM_001455
FOXO3
forkhead box O3
chr6_+_33589045 0.066 NM_002224
ITPR3
inositol 1,4,5-trisphosphate receptor, type 3
chr17_+_73629513 0.065 NM_001162995
C17orf109
chromosome 17 open reading frame 109
chr2_-_158300517 0.064 NM_004288
CYTIP
cytohesin 1 interacting protein
chr20_+_30598244 0.064 NM_080625
C20orf160
chromosome 20 open reading frame 160
chrX_+_122993536 0.063 NM_001204401
NM_001167
XIAP

X-linked inhibitor of apoptosis

chr2_+_150186498 0.062 NM_001195685
LYPD6
LY6/PLAUR domain containing 6
chr11_+_111411232 0.061 NM_178834
LAYN
layilin
chr9_+_132962871 0.060 NM_001128826
NCS1
neuronal calcium sensor 1
chr12_-_54673901 0.060 NM_012117
CBX5
chromobox homolog 5
chr10_+_118609022 0.060 NM_001242699
ENO4
enolase family member 4
chr19_-_39368889 0.060 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chr11_+_17373138 0.058 NM_001202439
B7H6
B7 homolog 6
chr11_-_33744497 0.058 NM_001127227
CD59
CD59 molecule, complement regulatory protein
chr4_-_119273874 0.057 NM_003619
PRSS12
protease, serine, 12 (neurotrypsin, motopsin)
chr12_+_56915587 0.057 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr1_+_90098643 0.055 NM_032270
LRRC8C
leucine rich repeat containing 8 family, member C
chr11_-_33744272 0.055 NM_001127223
NM_001127225
NM_001127226
CD59


CD59 molecule, complement regulatory protein


chr3_+_119421865 0.055 NM_033364
C3orf15
chromosome 3 open reading frame 15
chr1_+_162467594 0.055 NM_144624
NM_175866
UHMK1

U2AF homology motif (UHM) kinase 1

chr5_+_140165875 0.054 NM_018900
NM_031410
NM_031411
PCDHA1


protocadherin alpha 1


chr7_-_115670828 0.054 NM_001018058
NM_012252
TFEC

transcription factor EC

chr10_+_98592658 0.054 NM_032440
LCOR
ligand dependent nuclear receptor corepressor
chr18_+_42260774 0.054 NM_015559
SETBP1
SET binding protein 1
chr1_-_160990971 0.054 NM_016946
F11R
F11 receptor
chr1_-_102462789 0.054 NM_058170
OLFM3
olfactomedin 3
chr4_+_2813945 0.053 NM_001145855
SH3BP2
SH3-domain binding protein 2
chr1_+_182419255 0.053 NM_001137669
RGSL1
regulator of G-protein signaling like 1
chr4_+_153700932 0.053 NM_001025593
NM_001025595
NM_014447
ARFIP1


ADP-ribosylation factor interacting protein 1


chr8_-_91657898 0.053 NM_001008495
NM_001146273
TMEM64

transmembrane protein 64

chr4_-_90759446 0.052 NM_001146055
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr5_+_175792444 0.051 NM_173664
ARL10
ADP-ribosylation factor-like 10
chr5_+_112312392 0.050 NM_001242377
NM_152624
DCP2

DCP2 decapping enzyme homolog (S. cerevisiae)

chr14_-_75078669 0.050 NM_000428
LTBP2
latent transforming growth factor beta binding protein 2
chr12_-_14967091 0.050 NM_001013698
C12orf69
chromosome 12 open reading frame 69
chr11_-_74109417 0.050 NM_173582
PGM2L1
phosphoglucomutase 2-like 1
chrX_+_16737661 0.049 NM_032796
SYAP1
synapse associated protein 1
chr6_-_46138584 0.049 NM_021572
ENPP5
ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
chr12_-_52225700 0.049 NM_001013690
FIGNL2
fidgetin-like 2
chr3_-_71778268 0.049 NM_001134650
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr19_+_58361180 0.048 NM_001204817
NM_032828
ZNF587

zinc finger protein 587

chr16_-_73082169 0.048 NM_006885
ZFHX3
zinc finger homeobox 3
chrX_+_118714297 0.048 NM_181777
UBE2A
ubiquitin-conjugating enzyme E2A
chr5_+_140235594 0.047 NM_018901
NM_031859
NM_031860
PCDHA10


protocadherin alpha 10


chr1_+_162466963 0.047 NM_001184763
UHMK1
U2AF homology motif (UHM) kinase 1
chr11_-_34533117 0.047 NM_001243081
NM_198381
ELF5

E74-like factor 5 (ets domain transcription factor)

chrX_-_13835313 0.046 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr6_-_82462374 0.046 NM_017633
FAM46A
family with sequence similarity 46, member A
chr19_+_10381516 0.046 NM_000201
ICAM1
intercellular adhesion molecule 1
chr15_-_34681891 0.046 NM_181077
GOLGA8A
GOLGA8B
golgin A8 family, member A
golgin A8 family, member B
chr2_+_46769821 0.045 NM_012249
RHOQ
ras homolog gene family, member Q
chr10_+_98592015 0.044 NM_001170765
NM_001170766
LCOR

ligand dependent nuclear receptor corepressor

chr17_+_48351787 0.044 NM_153229
TMEM92
transmembrane protein 92
chr8_-_66546413 0.043 NM_018120
ARMC1
armadillo repeat containing 1
chr14_+_53196852 0.043 NM_001130701
NM_145251
STYX

serine/threonine/tyrosine interacting protein

chr5_-_43313581 0.041 NM_001098272
NM_002130
HMGCS1

3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)

chr1_-_173962050 0.041 NM_172071
RC3H1
ring finger and CCCH-type domains 1
chr1_+_74701070 0.041 NM_015978
TNNI3K
TNNI3 interacting kinase
chr10_-_94003002 0.041 NM_001178137
CPEB3
cytoplasmic polyadenylation element binding protein 3
chrX_-_24665454 0.041 NM_001163265
NM_004845
PCYT1B

phosphate cytidylyltransferase 1, choline, beta

chr19_-_57988891 0.041 NM_001024596
NM_001144068
ZNF772

zinc finger protein 772

chr14_+_67999915 0.040 NM_020715
PLEKHH1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr3_+_169755733 0.040 NM_014373
GPR160
G protein-coupled receptor 160
chr1_-_229478687 0.040 NM_145257
C1orf96
chromosome 1 open reading frame 96
chr20_-_43977023 0.039 NM_002999
SDC4
syndecan 4
chr12_+_11802726 0.039 NM_001987
ETV6
ets variant 6
chr2_-_26205437 0.039 NM_002254
KIF3C
kinesin family member 3C
chr1_+_244816349 0.039 NM_016076
PPPDE1
PPPDE peptidase domain containing 1
chr11_-_95657255 0.039 NM_001243571
NM_016156
NM_201278
NM_201281
MTMR2



myotubularin related protein 2



chr13_-_77460432 0.039 NM_138444
KCTD12
potassium channel tetramerisation domain containing 12
chr5_+_96294154 0.038 NM_175920
LNPEP
leucyl/cystinyl aminopeptidase
chrX_-_24690740 0.038 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr13_+_33160537 0.038 NM_015032
PDS5B
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr12_-_21548370 0.038 NM_134431
SLCO1A2
solute carrier organic anion transporter family, member 1A2
chr2_+_26256728 0.038 NM_016131
RAB10
RAB10, member RAS oncogene family
chr1_-_168105620 0.038 NM_153832
GPR161
G protein-coupled receptor 161
chr7_-_140098256 0.038 NM_032295
NM_207113
SLC37A3

solute carrier family 37 (glycerol-3-phosphate transporter), member 3

chr9_-_130712866 0.038 NM_203305
FAM102A
family with sequence similarity 102, member A
chr4_+_2819888 0.038 NM_001145856
SH3BP2
SH3-domain binding protein 2
chr11_-_73720281 0.038 NM_003356
NM_022803
UCP3

uncoupling protein 3 (mitochondrial, proton carrier)

chr22_+_21321446 0.037 NM_001146288
AIFM3
apoptosis-inducing factor, mitochondrion-associated, 3
chr14_+_68286495 0.037 NM_002877
NM_133509
NM_133510
RAD51B


RAD51 homolog B (S. cerevisiae)


chr19_-_38146288 0.037 NM_014898
ZFP30
zinc finger protein 30 homolog (mouse)
chr3_+_170075449 0.037 NM_001145098
NM_005414
SKIL

SKI-like oncogene

chr1_+_174844655 0.037 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr1_+_178694273 0.037 NM_152663
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr18_+_61637262 0.037 NM_001031848
NM_002640
NM_198833
SERPINB8


serpin peptidase inhibitor, clade B (ovalbumin), member 8


chr21_-_34863779 0.037 NM_017833
DNAJC28
DnaJ (Hsp40) homolog, subfamily C, member 28
chr19_+_21264952 0.036 NM_182515
ZNF714
zinc finger protein 714
chr5_+_96271345 0.036 NM_005575
LNPEP
leucyl/cystinyl aminopeptidase
chr3_+_42201658 0.036 NM_014965
TRAK1
trafficking protein, kinesin binding 1
chr6_-_36355342 0.036 NM_001207038
NM_001207035
NM_001207036
NM_001207037
NM_001207039
NM_001207040
NM_001207041
NM_016135
ETV7







ets variant 7







chr18_+_55297533 0.036 NM_001242804
LOC100505549
uncharacterized LOC100505549
chr4_-_103266286 0.036 NM_022154
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chrX_+_135230736 0.036 NM_001159700
FHL1
four and a half LIM domains 1
chr8_-_95961543 0.035 NM_001135733
NM_033285
TP53INP1

tumor protein p53 inducible nuclear protein 1

chr7_+_29846112 0.035 NM_001080529
WIPF3
WAS/WASL interacting protein family, member 3
chr7_-_152133071 0.035 NM_170606
MLL3
myeloid/lymphoid or mixed-lineage leukemia 3
chr4_-_103245468 0.035 NM_001135148
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr1_+_28585959 0.035 NM_031459
SESN2
sestrin 2
chrX_+_135251454 0.035 NM_001159704
FHL1
four and a half LIM domains 1
chr22_+_40440664 0.035 NM_001024843
TNRC6B
trinucleotide repeat containing 6B
chr2_+_45878912 0.035 NM_005400
PRKCE
protein kinase C, epsilon
chr1_-_161279724 0.034 NM_000530
MPZ
myelin protein zero
chr21_-_34863968 0.034 NM_001040192
DNAJC28
DnaJ (Hsp40) homolog, subfamily C, member 28
chr16_+_19422056 0.034 NM_001105248
NM_001105249
TMC5

transmembrane channel-like 5

chr17_+_7311501 0.034 NM_020795
NLGN2
neuroligin 2
chr19_-_46146984 0.034 NM_001193269
EML2
echinoderm microtubule associated protein like 2
chr13_+_44453419 0.034 NM_001128303
LACC1
laccase (multicopper oxidoreductase) domain containing 1
chr16_-_74641014 0.034 NM_001145666
NM_001145667
NM_012201
GLG1


golgi glycoprotein 1


chr4_+_108814419 0.033 NM_001136257
NM_152621
SGMS2

sphingomyelin synthase 2

chr10_+_104535887 0.033 NM_017787
C10orf26
chromosome 10 open reading frame 26
chr19_-_46148606 0.033 NM_001193268
EML2
echinoderm microtubule associated protein like 2
chr4_+_47487230 0.033 NM_020453
ATP10D
ATPase, class V, type 10D
chr1_-_108507474 0.033 NM_006113
VAV3
vav 3 guanine nucleotide exchange factor
chr14_+_32546445 0.033 NM_001030055
NM_001173
ARHGAP5

Rho GTPase activating protein 5

chr2_-_144994905 0.033 NM_024659
GTDC1
glycosyltransferase-like domain containing 1
chr1_-_89641722 0.033 NM_207398
GBP7
guanylate binding protein 7
chr12_+_111843743 0.033 NM_005475
SH2B3
SH2B adaptor protein 3
chr5_-_158637060 0.033 NM_001199380
RNF145
ring finger protein 145
chr12_+_101188373 0.033 NM_178826
ANO4
anoctamin 4
chr1_-_205719340 0.033 NM_022731
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr16_-_15982446 0.032 NM_144600
FOPNL
FGFR1OP N-terminal like
chr17_+_6899383 0.032 NM_000697
ALOX12
arachidonate 12-lipoxygenase
chr17_+_33570079 0.032 NM_144975
SLFN5
schlafen family member 5
chr10_-_97200895 0.032 NM_001034954
NM_001034955
NM_001034956
NM_001034957
NM_006434
SORBS1




sorbin and SH3 domain containing 1




chr3_+_170077410 0.031 NM_001145097
NM_001248008
SKIL

SKI-like oncogene

chr17_+_48348766 0.031 NM_001168215
TMEM92
transmembrane protein 92
chr1_+_171060017 0.031 NM_001002294
NM_006894
FMO3

flavin containing monooxygenase 3

chr3_+_45927995 0.031 NM_006641
NM_031200
CCR9

chemokine (C-C motif) receptor 9

chr5_-_137071703 0.031 NM_017415
KLHL3
kelch-like 3 (Drosophila)
chr4_-_74486100 0.031 NM_177532
NM_201431
RASSF6

Ras association (RalGDS/AF-6) domain family member 6

chr3_-_11685395 0.031 NM_001128219
VGLL4
vestigial like 4 (Drosophila)
chr16_+_66460815 0.031 NM_001136106
NM_001178020
NM_001197224
NM_001197225
BEAN1



brain expressed, associated with NEDD4, 1



chr22_-_17680485 0.031 NM_177405
CECR1
cat eye syndrome chromosome region, candidate 1
chr10_-_97321094 0.031 NM_015385
NM_024991
SORBS1

sorbin and SH3 domain containing 1

chr12_-_21654484 0.031 NM_002907
NM_032941
RECQL

RecQ protein-like (DNA helicase Q1-like)

chr16_-_48399783 0.031 NM_001006610
SIAH1
seven in absentia homolog 1 (Drosophila)
chr14_+_38677186 0.031 NM_001049
SSTR1
somatostatin receptor 1
chr1_-_92371558 0.031 NM_001195684
TGFBR3
transforming growth factor, beta receptor III
chr2_-_145052059 0.031 NM_001006636
GTDC1
glycosyltransferase-like domain containing 1
chr12_-_122231554 0.030 NM_019034
RHOF
ras homolog gene family, member F (in filopodia)
chr15_-_52861177 0.030 NM_006628
ARPP19
cAMP-regulated phosphoprotein, 19kDa
chr2_-_158485393 0.030 NM_001111032
NM_001111033
NM_145259
ACVR1C


activin A receptor, type IC


chr17_+_30593194 0.030 NM_138328
RHBDL3
rhomboid, veinlet-like 3 (Drosophila)
chr4_+_2820540 0.030 NM_003023
SH3BP2
SH3-domain binding protein 2
chr5_+_140220811 0.030 NM_018911
NM_031856
PCDHA8

protocadherin alpha 8

chr22_-_39548448 0.030 NM_175709
CBX7
chromobox homolog 7
chr6_+_25962978 0.030 NM_006355
TRIM38
tripartite motif containing 38
chr21_+_34697197 0.030 NM_000629
IFNAR1
interferon (alpha, beta and omega) receptor 1
chr17_-_76921453 0.029 NM_003255
TIMP2
TIMP metallopeptidase inhibitor 2
chr19_-_46142662 0.029 NM_012155
EML2
echinoderm microtubule associated protein like 2
chr13_+_33590477 0.029 NM_004795
KL
klotho
chr16_-_20753117 0.029 NM_017736
THUMPD1
THUMP domain containing 1
chr9_-_14314036 0.029 NM_001190737
NM_005596
NFIB

nuclear factor I/B

chr22_+_46546498 0.029 NM_001001928
NM_005036
PPARA

peroxisome proliferator-activated receptor alpha

chr3_-_184870727 0.029 NM_001025266
C3orf70
chromosome 3 open reading frame 70
chr16_+_19467771 0.029 NM_024780
TMC5
transmembrane channel-like 5
chr2_-_158454025 0.029 NM_001111031
ACVR1C
activin A receptor, type IC
chr7_+_89840999 0.029 NM_001244944
NM_001244945
NM_152999
NM_001040665
NM_001244946
STEAP2




STEAP family member 2, metalloreductase




chr1_-_115259433 0.029 NM_002524
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr13_-_46961634 0.029 NM_025113
KIAA0226L
KIAA0226-like
chr13_+_108870713 0.029 NM_032859
ABHD13
abhydrolase domain containing 13
chr12_-_51419923 0.029 NM_001174129
SLC11A2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr3_+_52828783 0.028 NM_002217
ITIH3
inter-alpha-trypsin inhibitor heavy chain 3
chr13_-_47470967 0.028 NM_000621
NM_001165947
HTR2A

5-hydroxytryptamine (serotonin) receptor 2A


Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.