Motif ID: IRF1,2,7.p3

Z-value: 1.339


Transcription factors associated with IRF1,2,7.p3:

Gene SymbolEntrez IDGene Name
IRF1 3659 interferon regulatory factor 1
IRF2 3660 interferon regulatory factor 2
IRF7 3665 interferon regulatory factor 7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
IRF2hg19_v1_chr4_-_185395616_1853957460.305.6e-01Click!
IRF7hg19_v1_chr11_-_615920_615952-0.207.1e-01Click!
IRF1hg19_v1_chr5_-_131826426_1318265360.177.4e-01Click!


Activity profile for motif IRF1,2,7.p3.

activity profile for motif IRF1,2,7.p3


Sorted Z-values histogram for motif IRF1,2,7.p3

Sorted Z-values for motif IRF1,2,7.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of IRF1,2,7.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_116782555 1.353 NM_001010919
FAM26F
family with sequence similarity 26, member F
chr5_+_131746579 1.149 C5orf56
chromosome 5 open reading frame 56
chr10_+_91152321 1.038 NM_001548
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr1_+_79086087 0.915 NM_006820
IFI44L
interferon-induced protein 44-like
chr16_-_3422282 0.822 NM_001190476
MTRNR2L4
MT-RNR2-like 4
chr22_+_36044412 0.723 NM_030641
APOL6
apolipoprotein L, 6
chr6_-_46889620 0.617 NM_001098518
GPR116
G protein-coupled receptor 116
chr8_+_143808593 0.616 NM_016647
C8orf55
chromosome 8 open reading frame 55
chr17_-_40264687 0.612 NM_024119
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr21_+_34144410 0.582 C21orf49
chromosome 21 open reading frame 49
chr22_-_22874597 0.536 NM_080740
ZNF280A
zinc finger protein 280A
chr16_-_67970651 0.505 PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr16_-_67970734 0.497 NM_002801
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr1_-_148176392 0.496


chr6_+_26440699 0.468 NM_001242803
NM_006994
NM_197974
BTN3A3


butyrophilin, subfamily 3, member A3


chr6_-_121655606 0.448 NM_152730
C6orf170
chromosome 6 open reading frame 170
chr5_-_149792276 0.442 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr2_+_231280870 0.437 NM_001080391
NM_001206701
NM_001206702
NM_001206703
NM_003113
SP100




SP100 nuclear antigen




chr17_-_43339433 0.429 NM_152343
C17orf46
chromosome 17 open reading frame 46
chr2_+_231280933 0.421 SP100
SP100 nuclear antigen
chr6_+_26402464 0.413 NM_001145008
NM_001145009
NM_007048
NM_194441
BTN3A1



butyrophilin, subfamily 3, member A1



chr1_-_168106535 0.407 GPR161
G protein-coupled receptor 161
chr1_+_97260515 0.403


chr5_+_96212167 0.397 ERAP2
endoplasmic reticulum aminopeptidase 2
chrX_+_71364033 0.397 NM_207422
FLJ44635
TPT1-like protein
chr6_-_31239489 0.396 HLA-B
HLA-C
major histocompatibility complex, class I, B
major histocompatibility complex, class I, C
chr6_-_87804773 0.396 NM_000735
NM_001252383
CGA

glycoprotein hormones, alpha polypeptide

chr22_+_36044475 0.386 APOL6
apolipoprotein L, 6
chr5_-_95158365 0.385 GLRX
glutaredoxin (thioltransferase)
chr4_-_169239816 0.385 NM_017631
DDX60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr17_+_41363845 0.384 NM_145041
TMEM106A
transmembrane protein 106A
chr21_-_34185943 0.380 NM_001162495
NM_001162496
NM_019596
C21orf62


chromosome 21 open reading frame 62


chr1_-_168106727 0.379 GPR161
G protein-coupled receptor 161
chrX_+_30261847 0.360 NM_002363
NM_177415
MAGEB1

melanoma antigen family B, 1

chr2_+_85811530 0.353 NM_006634
VAMP5
vesicle-associated membrane protein 5 (myobrevin)
chr16_-_75529289 0.326


chr6_+_26365397 0.325 NM_001197247
NM_001197249
NM_007047
NM_001197248
BTN3A2



butyrophilin, subfamily 3, member A2



chr19_-_48614013 0.325 NM_001159322
NM_001159323
NM_003706
PLA2G4C


phospholipase A2, group IVC (cytosolic, calcium-independent)


chr4_+_186990308 0.325 NM_003265
TLR3
toll-like receptor 3
chr5_-_95158465 0.313 NM_001118890
NM_001243658
NM_001243659
NM_002064
GLRX



glutaredoxin (thioltransferase)



chr6_+_87969619 0.313 ZNF292
zinc finger protein 292
chr1_-_168106810 0.309 GPR161
G protein-coupled receptor 161
chr1_+_156030965 0.308 NM_020387
RAB25
RAB25, member RAS oncogene family
chr2_+_231280906 0.305 SP100
SP100 nuclear antigen
chr12_+_113376001 0.296 OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr17_-_67240955 0.292 NM_080282
ABCA10
ATP-binding cassette, sub-family A (ABC1), member 10
chr9_-_73483933 0.290 NM_001007470
NM_020952
NM_024971
NM_206944
NM_206945
NM_206946
NM_206947
NM_206948
TRPM3







transient receptor potential cation channel, subfamily M, member 3







chr1_-_24469571 0.285 NM_021258
IL22RA1
interleukin 22 receptor, alpha 1
chr19_-_43032525 0.283 NM_001024912
NM_001184813
NM_001184815
NM_001184816
NM_001205344
NM_001712
CEACAM1





carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)





chr4_+_77135192 0.282 NM_001242936
FAM47E
family with sequence similarity 47, member E
chr1_+_948846 0.281 NM_005101
ISG15
ISG15 ubiquitin-like modifier
chr7_+_105603656 0.280 NM_152750
CDHR3
cadherin-related family member 3
chr11_-_104972147 0.276 NM_001007232
NM_001223
NM_033292
NM_033293
NM_033294
NM_033295
CARD17
CASP1




caspase recruitment domain family, member 17
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)




chr1_-_149908721 0.273 MTMR11
myotubularin related protein 11
chr21_+_37507209 0.270 NM_001236
CBR3
carbonyl reductase 3
chr2_+_132480063 0.266 NM_013310
C2orf27A
chromosome 2 open reading frame 27A
chr20_+_388963 0.266 RBCK1
RanBP-type and C3HC4-type zinc finger containing 1
chr12_+_12224401 0.262 NM_030766
NM_138722
BCL2L14

BCL2-like 14 (apoptosis facilitator)

chr17_+_78234626 0.262 NM_020914
NM_020954
RNF213

ring finger protein 213

chr3_+_122399665 0.253 NM_017554
PARP14
poly (ADP-ribose) polymerase family, member 14
chr12_+_113376301 0.253 OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr2_-_87248942 0.246 NM_002665
NM_001032392
PLGLB2
PLGLB1
plasminogen-like B2
plasminogen-like B1
chr6_+_87865261 0.245 NM_015021
ZNF292
zinc finger protein 292
chr6_+_25963398 0.245 TRIM38
tripartite motif containing 38
chr11_+_28129797 0.245 NM_001113528
NM_152636
METTL15

methyltransferase like 15

chr5_-_156390206 0.244 NM_001146726
NM_138379
TIMD4

T-cell immunoglobulin and mucin domain containing 4

chr3_-_172241060 0.243 NM_001190943
NM_001190942
NM_003810
TNFSF10


tumor necrosis factor (ligand) superfamily, member 10


chr1_+_150480486 0.239 NM_001202858
NM_004425
NM_022664
ECM1


extracellular matrix protein 1


chr1_-_47695442 0.237 NM_003189
TAL1
T-cell acute lymphocytic leukemia 1
chr1_+_120254418 0.236 NM_006623
PHGDH
phosphoglycerate dehydrogenase
chr12_+_113376226 0.235 NM_006187
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr20_+_388941 0.234 RBCK1
RanBP-type and C3HC4-type zinc finger containing 1
chr7_+_140103842 0.234 NM_001008749
RAB19
RAB19, member RAS oncogene family
chr10_+_134210691 0.233 NM_001098637
NM_138499
PWWP2B

PWWP domain containing 2B

chr2_+_241544819 0.232 NM_001195381
NM_001195382
GPR35

G protein-coupled receptor 35

chr19_-_10679328 0.229 CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr1_+_181003143 0.229 MR1
major histocompatibility complex, class I-related
chr20_+_388717 0.226 RBCK1
RanBP-type and C3HC4-type zinc finger containing 1
chr3_-_145968819 0.225 PLSCR4
phospholipid scramblase 4
chr12_+_53442972 0.224 TENC1
tensin like C1 domain containing phosphatase (tensin 2)
chr11_+_5646206 0.222 NM_021616
TRIM34
tripartite motif containing 34
chr3_+_169539709 0.219 NM_001080460
LRRIQ4
leucine-rich repeats and IQ motif containing 4
chrX_+_77166223 0.218 ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chrX_-_15620191 0.218 NM_021804
ACE2
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr11_+_28131830 0.217 METTL15
methyltransferase like 15
chr13_+_53216564 0.215 HNRNPA1L2
heterogeneous nuclear ribonucleoprotein A1-like 2
chr16_+_28303622 0.214 NM_001024401
SBK1
SH3-binding domain kinase 1
chr1_+_181003138 0.212 MR1
major histocompatibility complex, class I-related
chr16_-_28437663 0.211 NM_001199142
EIF3C
eukaryotic translation initiation factor 3, subunit C
chr7_-_73256838 0.210 NM_152559
WBSCR27
Williams Beuren syndrome chromosome region 27
chr16_-_21289637 0.210 CRYM
crystallin, mu
chr1_+_150480584 0.207 ECM1
extracellular matrix protein 1
chrX_+_77166178 0.204 NM_000052
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr17_-_38074842 0.204 NM_001042471
NM_001165958
NM_001165959
GSDMB


gasdermin B


chr6_-_32821592 0.201 TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chrX_+_14547419 0.201 NM_001118885
NM_001118886
NM_001171942
NM_002063
GLRA2



glycine receptor, alpha 2



chr17_-_67057046 0.200 NM_080283
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr21_+_42792441 0.199 NM_001144925
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr22_-_32651317 0.199 NM_014227
SLC5A4
solute carrier family 5 (low affinity glucose cotransporter), member 4
chr20_+_389346 0.198 RBCK1
RanBP-type and C3HC4-type zinc finger containing 1
chr19_-_47735858 0.198 NM_001127240
NM_001127241
NM_001127242
BBC3


BCL2 binding component 3


chr17_+_46908371 0.195 NM_005831
CALCOCO2
calcium binding and coiled-coil domain 2
chr3_+_46283871 0.193 NM_001164680
NM_001837
NM_178328
NM_178329
CCR3



chemokine (C-C motif) receptor 3



chr2_+_143635225 0.186 KYNU
kynureninase
chr12_+_102271082 0.186 NM_018370
DRAM1
DNA-damage regulated autophagy modulator 1
chr11_+_65266642 0.178


chr16_+_54965110 0.176 NM_001252197
NM_005853
IRX5

iroquois homeobox 5

chrX_+_102965836 0.172 NM_182541
TMEM31
transmembrane protein 31
chrX_-_109561314 0.172 NM_001025580
NM_015365
AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr6_-_32821743 0.172 NM_000593
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr3_+_48507621 0.171 TREX1
three prime repair exonuclease 1
chr19_-_49371710 0.171 NM_001161354
NM_020904
PLEKHA4

pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4

chr16_-_75529278 0.170


chr11_+_32112607 0.170 RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr1_-_161039745 0.170 NM_001025598
NM_181720
ARHGAP30

Rho GTPase activating protein 30

chr20_+_388693 0.169 NM_006462
NM_031229
RBCK1

RanBP-type and C3HC4-type zinc finger containing 1

chr6_-_138189313 0.169


chr9_-_88874518 0.169 NM_001010907
C9orf153
chromosome 9 open reading frame 153
chr10_+_101542554 0.169 ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr20_+_825284 0.168 NM_031424
FAM110A
family with sequence similarity 110, member A
chrX_+_100878101 0.167 NM_016607
NM_177947
ARMCX3

armadillo repeat containing, X-linked 3

chr21_+_42797977 0.167 NM_002462
NM_001178046
MX1

myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)

chrX_-_106362018 0.167 RBM41
RNA binding motif protein 41
chr5_-_114631964 0.166 NM_152549
CCDC112
coiled-coil domain containing 112
chr6_-_32821412 0.164 TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr12_-_54778298 0.163 ZNF385A
zinc finger protein 385A
chr17_-_33885106 0.162 NM_001129820
SLFN14
schlafen family member 14
chr8_-_22926490 0.162 NM_003842
NM_147187
TNFRSF10B

tumor necrosis factor receptor superfamily, member 10b

chr14_+_100111446 0.161 NM_001127258
NM_032425
HHIPL1

HHIP-like 1

chr11_-_5526833 0.160 NM_001005567
OR51B5
HBE1
olfactory receptor, family 51, subfamily B, member 5
hemoglobin, epsilon 1
chr20_+_1246959 0.160 NM_014723
SNPH
syntaphilin
chr12_+_29376596 0.159 NM_018099
FAR2
fatty acyl CoA reductase 2
chr10_+_5238756 0.159 NM_001818
AKR1C4
aldo-keto reductase family 1, member C4 (chlordecone reductase; 3-alpha hydroxysteroid dehydrogenase, type I; dihydrodiol dehydrogenase 4)
chr13_+_24463006 0.159 NM_001014442
C1QTNF9B-AS1
C1QTNF9B antisense RNA 1 (non-protein coding)
chr2_-_133539627 0.158 NCKAP5
NCK-associated protein 5
chr1_+_181003066 0.157 MR1
major histocompatibility complex, class I-related
chr4_-_100140330 0.156 NM_000672
NM_001102470
ADH6

alcohol dehydrogenase 6 (class V)

chr22_-_36635552 0.156 APOL2
apolipoprotein L, 2
chr12_+_123319293 0.155 HIP1R
huntingtin interacting protein 1 related
chr2_-_175629140 0.155 NM_000079
NM_001039523
CHRNA1

cholinergic receptor, nicotinic, alpha 1 (muscle)

chr10_-_102279590 0.154 NM_015490
SEC31B
SEC31 homolog B (S. cerevisiae)
chr1_+_32674694 0.153 NM_001099434
DCDC2B
doublecortin domain containing 2B
chr15_-_45003513 0.153


chr1_-_182558344 0.152 NM_021133
RNASEL
ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent)
chr6_-_32806545 0.151 NM_000544
NM_018833
TAP2

transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)

chr8_+_95835586 0.150 INTS8
integrator complex subunit 8
chr12_-_71148063 0.150 PTPRR
protein tyrosine phosphatase, receptor type, R
chr9_-_35812143 0.150 NM_001039592
NM_172312
SPAG8

sperm associated antigen 8

chr17_+_7342688 0.148 NM_004112
FGF11
fibroblast growth factor 11
chr11_+_7506599 0.147 NM_198474
OLFML1
olfactomedin-like 1
chr2_-_191184770 0.146 NM_014362
NM_198047
HIBCH

3-hydroxyisobutyryl-CoA hydrolase

chr1_-_161039703 0.145 ARHGAP30
Rho GTPase activating protein 30
chrX_-_118925556 0.145 NM_001000
RPL39
ribosomal protein L39
chr7_+_128580725 0.145 NM_001098627
IRF5
interferon regulatory factor 5
chr17_-_76732944 0.145


chr4_+_37892698 0.144 NM_015173
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr17_+_48348766 0.141 NM_001168215
TMEM92
transmembrane protein 92
chr3_-_28390506 0.140 NM_001134432
NM_001134433
NM_022461
AZI2


5-azacytidine induced 2


chr9_+_100174179 0.138 NM_014290
TDRD7
tudor domain containing 7
chr2_+_61389628 0.138 NM_001143959
C2orf74
chromosome 2 open reading frame 74
chr6_+_136172802 0.135 NM_018945
PDE7B
phosphodiesterase 7B
chr7_-_92747269 0.135 SAMD9
sterile alpha motif domain containing 9
chr14_+_35452194 0.135 SRP54
signal recognition particle 54kDa
chr8_+_95835517 0.134 NM_017864
INTS8
integrator complex subunit 8
chr1_-_25291474 0.132 NM_001031680
RUNX3
runt-related transcription factor 3
chr10_+_101542460 0.132 NM_000392
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr6_-_26197477 0.131 HIST1H3D
histone cluster 1, H3d
chr12_-_71148383 0.131 NM_130846
NM_001207016
PTPRR

protein tyrosine phosphatase, receptor type, R

chr3_+_46448678 0.129 NM_003965
NM_001130910
CCRL2

chemokine (C-C motif) receptor-like 2

chr10_-_103347978 0.127 NM_001174084
NM_001174085
NM_013274
POLL


polymerase (DNA directed), lambda


chr19_+_49977817 0.126 NM_001204503
FLT3LG
fms-related tyrosine kinase 3 ligand
chr21_+_45139018 0.125


chr6_-_46703042 0.125 PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr14_+_70918873 0.124 NM_003813
ADAM21
ADAM metallopeptidase domain 21
chr11_-_86383653 0.123 NM_001161586
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr19_-_4916814 0.123


chr3_+_159706622 0.123 NM_000882
IL12A
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
chr8_+_9911747 0.122 MSRA
methionine sulfoxide reductase A
chr2_+_173686314 0.121 NM_001100397
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr2_+_88047603 0.120 NM_002665
NM_001032392
PLGLB2
PLGLB1
plasminogen-like B2
plasminogen-like B1
chr2_-_191184485 0.120 HIBCH
3-hydroxyisobutyryl-CoA hydrolase
chr8_-_110655418 0.119 NM_001099756
SYBU
syntabulin (syntaxin-interacting)
chr8_-_145060563 0.118 PARP10
poly (ADP-ribose) polymerase family, member 10
chr12_-_118541655 0.118 NM_019086
VSIG10
V-set and immunoglobulin domain containing 10
chr17_+_48821106 0.118 LUC7L3
LUC7-like 3 (S. cerevisiae)
chr22_+_39436608 0.118 NM_001006666
NM_145298
APOBEC3F

apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F

chr19_-_39368889 0.117 NM_001195833
NM_198445
RINL

Ras and Rab interactor-like

chr16_-_28303366 0.117


chr6_-_133119625 0.117 NM_052831
C6orf192
chromosome 6 open reading frame 192
chr16_+_29831714 0.116 NM_005115
NM_017458
MVP

major vault protein

chr11_-_105010460 0.115 NM_021571
CARD18
caspase recruitment domain family, member 18
chr2_-_68290114 0.115 C1D
C1D nuclear receptor corepressor
chr2_+_202047803 0.115 CASP10
caspase 10, apoptosis-related cysteine peptidase
chr1_+_101003692 0.115 NM_022049
GPR88
G protein-coupled receptor 88
chr10_+_91061705 0.115 NM_001547
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr1_+_36387788 0.114 EIF2C1
eukaryotic translation initiation factor 2C, 1
chr7_-_83270746 0.114 NM_001178129
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr4_-_140201339 0.113 NM_032623
C4orf49
chromosome 4 open reading frame 49
chr12_-_11002051 0.113 NM_001098538
NM_007244
PRR4

proline rich 4 (lacrimal)

chr19_+_10196972 0.113 C19orf66
chromosome 19 open reading frame 66

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.