Motif ID: KLF4.p3

Z-value: 2.278


Transcription factors associated with KLF4.p3:

Gene SymbolEntrez IDGene Name
KLF4 9314 Kruppel-like factor 4 (gut)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
KLF4hg19_v1_chr9_-_110251308_1102515890.532.8e-01Click!


Activity profile for motif KLF4.p3.

activity profile for motif KLF4.p3


Sorted Z-values histogram for motif KLF4.p3

Sorted Z-values for motif KLF4.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of KLF4.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_-_56884488 4.656 PPP4R1L
protein phosphatase 4, regulatory subunit 1-like
chr1_+_995109 2.934 LOC100288175
uncharacterized LOC100288175
chr19_-_41196419 2.722 NM_004756
NUMBL
numb homolog (Drosophila)-like
chr19_-_49622278 2.714 NM_018111
C19orf73
chromosome 19 open reading frame 73
chr12_-_49582296 2.061 TUBA1A
tubulin, alpha 1a
chr20_-_3388219 2.014 NM_001009984
C20orf194
chromosome 20 open reading frame 194
chr8_-_12990502 1.954 DLC1
deleted in liver cancer 1
chr8_-_17658711 1.940


chr19_-_17007674 1.803 CPAMD8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr1_-_6321034 1.800 NM_207370
GPR153
G protein-coupled receptor 153
chr12_-_105478218 1.794 NM_001034173
ALDH1L2
aldehyde dehydrogenase 1 family, member L2
chr17_+_81037504 1.782 NM_001004431
METRNL
meteorin, glial cell differentiation regulator-like
chr21_-_37528578 1.733 LOC100506428
uncharacterized LOC100506428
chr2_-_26205327 1.729 KIF3C
kinesin family member 3C
chr19_-_50143350 1.716 NM_006270
RRAS
related RAS viral (r-ras) oncogene homolog
chr5_-_16617085 1.674 NM_001034850
FAM134B
family with sequence similarity 134, member B
chr19_+_33166312 1.666 NM_207391
RGS9BP
regulator of G protein signaling 9 binding protein
chr12_-_49582800 1.636 NM_006009
TUBA1A
tubulin, alpha 1a
chr1_-_212873197 1.628 BATF3
basic leucine zipper transcription factor, ATF-like 3
chr20_+_33464404 1.580 ACSS2
acyl-CoA synthetase short-chain family member 2
chr4_-_186392847 1.579 NM_001145411
NM_152775
CCDC110

coiled-coil domain containing 110

chr22_+_43547526 1.548 NM_000714
NM_007311
TSPO

translocator protein (18kDa)

chr7_+_99775521 1.543 NM_012447
STAG3
stromal antigen 3
chr20_+_33464327 1.533 NM_001076552
NM_018677
ACSS2

acyl-CoA synthetase short-chain family member 2

chr7_+_44078677 1.531 FLJ35390
uncharacterized LOC255031
chr5_+_71403040 1.523 NM_005909
MAP1B
microtubule-associated protein 1B
chr9_-_130679210 1.518 NM_175039
NM_175040
ST6GALNAC4

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4

chr1_-_212873306 1.506 NM_018664
BATF3
basic leucine zipper transcription factor, ATF-like 3
chr17_+_43299277 1.501 NM_005892
FMNL1
formin-like 1
chr4_-_101111606 1.473 NM_145244
DDIT4L
DNA-damage-inducible transcript 4-like
chr5_+_177540465 1.455 NM_015111
N4BP3
NEDD4 binding protein 3
chr10_-_126849556 1.434 NM_001083914
CTBP2
C-terminal binding protein 2
chr2_+_23608297 1.428 NM_052920
KLHL29
kelch-like 29 (Drosophila)
chr7_+_64498643 1.424 CCT6P3
chaperonin containing TCP1, subunit 6 (zeta) pseudogene 3
chrX_+_153237990 1.423 NM_003492
TMEM187
transmembrane protein 187
chr2_+_112812799 1.420 NM_032824
TMEM87B
transmembrane protein 87B
chr19_+_57050299 1.420 NM_020828
ZFP28
zinc finger protein 28 homolog (mouse)
chr16_+_2039945 1.385 NM_004209
SYNGR3
synaptogyrin 3
chr11_+_35160832 1.381 CD44
CD44 molecule (Indian blood group)
chr3_-_109035239 1.375 NM_138815
DPPA2
developmental pluripotency associated 2
chr22_-_50708720 1.372 NM_002751
MAPK11
mitogen-activated protein kinase 11
chr20_+_42143045 1.369 NM_015478
L3MBTL1
l(3)mbt-like 1 (Drosophila)
chr5_-_138739755 1.362 NM_194296
SPATA24
spermatogenesis associated 24
chr19_-_19738973 1.362 NM_004720
LPAR2
lysophosphatidic acid receptor 2
chr15_+_90931470 1.357 NM_003870
IQGAP1
IQ motif containing GTPase activating protein 1
chr19_+_41284068 1.339 NM_016154
RAB4B
RAB4B, member RAS oncogene family
chr1_-_11714738 1.328 NM_012168
FBXO2
F-box protein 2
chr20_-_3388586 1.309 C20orf194
chromosome 20 open reading frame 194
chr16_+_19179534 1.307 NM_016524
SYT17
synaptotagmin XVII
chr3_+_127391768 1.303 NM_032548
NM_172027
ABTB1

ankyrin repeat and BTB (POZ) domain containing 1

chr7_+_43152196 1.291 NM_015052
HECW1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr3_-_129830273 1.285


chr1_+_233463513 1.285 NM_032435
KIAA1804
mixed lineage kinase 4
chr7_+_152161119 1.267 LOC100128822
uncharacterized LOC100128822
chr9_+_139972195 1.266 UAP1L1
UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr3_-_129830320 1.261


chr17_+_48638339 1.247 NM_018896
NM_198376
NM_198377
NM_198378
NM_198379
NM_198380
NM_198382
NM_198383
NM_198384
NM_198385
NM_198386
NM_198387
NM_198388
NM_198396
NM_198397
CACNA1G














calcium channel, voltage-dependent, T type, alpha 1G subunit














chr12_+_120933832 1.239 NM_001037495
NM_003746
DYNLL1

dynein, light chain, LC8-type 1

chr2_-_26205437 1.239 NM_002254
KIF3C
kinesin family member 3C
chr9_+_103235634 1.231 TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr12_-_51785192 1.230 NM_007210
GALNT6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
chr2_+_10183630 1.221 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr18_-_19748928 1.212 LOC100128893
uncharacterized LOC100128893
chr3_-_48594209 1.206 NM_004567
PFKFB4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr8_+_32405727 1.204 NM_001160002
NM_001160004
NM_001160005
NM_001160007
NM_001160008
NM_004495
NM_013956
NM_013957
NM_013958
NM_013960
NM_013964
NRG1










neuregulin 1










chr15_+_90931509 1.192 IQGAP1
IQ motif containing GTPase activating protein 1
chr12_+_120933916 1.191 DYNLL1
dynein, light chain, LC8-type 1
chr12_+_116971196 1.189 LINC00173
long intergenic non-protein coding RNA 173
chr15_+_90931449 1.187 IQGAP1
IQ motif containing GTPase activating protein 1
chr17_-_34900655 1.175 DKFZp564H213
uncharacterized LOC440432
chr20_-_35201677 1.173


chr15_+_90931489 1.172 IQGAP1
IQ motif containing GTPase activating protein 1
chr11_-_560706 1.167 NM_173573
C11orf35
chromosome 11 open reading frame 35
chr12_-_58132028 1.159 NM_001122772
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr6_-_31239489 1.159 HLA-B
HLA-C
major histocompatibility complex, class I, B
major histocompatibility complex, class I, C
chr10_+_13142055 1.149 NM_001008211
NM_001008212
NM_001008213
NM_021980
OPTN



optineurin



chr14_-_105647520 1.147 NM_177533
NUDT14
nudix (nucleoside diphosphate linked moiety X)-type motif 14
chr19_-_36523540 1.139 NM_001199570
CLIP3
CAP-GLY domain containing linker protein 3
chr8_+_26371461 1.137 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chr11_+_35160666 1.134 CD44
CD44 molecule (Indian blood group)
chr9_+_116111811 1.128 NM_017688
BSPRY
B-box and SPRY domain containing
chr22_+_29468887 1.127 NM_001039570
NM_032045
KREMEN1

kringle containing transmembrane protein 1

chr1_-_1475739 1.123 NM_001114748
TMEM240
transmembrane protein 240
chr19_-_39227588 1.120 CAPN12
calpain 12
chr2_-_230579198 1.120 NM_139072
DNER
delta/notch-like EGF repeat containing
chr8_-_144923019 1.118 NM_178564
NRBP2
nuclear receptor binding protein 2
chr19_+_45504686 1.115 NM_006509
RELB
v-rel reticuloendotheliosis viral oncogene homolog B
chr14_+_96858436 1.111 NM_152327
AK7
adenylate kinase 7
chr20_-_60795270 1.110 NM_007232
HRH3
histamine receptor H3
chr1_+_40506347 1.109 CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr19_+_41284161 1.106 RAB4B-EGLN2
RAB4B
RAB4B-EGLN2 readthrough
RAB4B, member RAS oncogene family
chr4_+_85504056 1.103 NM_001263
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr8_-_26371387 1.102 NM_007257
PNMA2
paraneoplastic antigen MA2
chr19_-_6767417 1.101 NM_005490
SH2D3A
SH2 domain containing 3A
chr15_-_82338348 1.100 NM_032246
MEX3B
mex-3 homolog B (C. elegans)
chr12_+_58003962 1.100 NM_001111270
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr1_+_40506254 1.094 NM_001105530
NM_006367
CAP1

CAP, adenylate cyclase-associated protein 1 (yeast)

chrX_+_49028183 1.094 NM_002668
PLP2
proteolipid protein 2 (colonic epithelium-enriched)
chr12_+_58148775 1.090 NM_138396
MARCH9
membrane-associated ring finger (C3HC4) 9
chr19_+_49617631 1.089 LIN7B
lin-7 homolog B (C. elegans)
chr12_+_58005217 1.084 NM_182947
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr13_-_110438896 1.083 NM_003749
IRS2
insulin receptor substrate 2
chr11_-_2950593 1.082 NM_003311
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr10_+_74033676 1.081 NM_019058
DDIT4
DNA-damage-inducible transcript 4
chr9_+_139971938 1.073 NM_207309
UAP1L1
UDP-N-acteylglucosamine pyrophosphorylase 1-like 1
chr19_+_30156326 1.073 NM_024310
PLEKHF1
pleckstrin homology domain containing, family F (with FYVE domain) member 1
chr1_+_28585959 1.067 NM_031459
SESN2
sestrin 2
chr11_-_63684315 1.056 NM_173587
RCOR2
REST corepressor 2
chr3_+_135684606 1.053 PPP2R3A
protein phosphatase 2, regulatory subunit B'', alpha
chr18_+_34409058 1.053 NM_020776
KIAA1328
KIAA1328
chr9_+_103235489 1.051 NM_003692
TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr11_+_77899857 1.051 NM_020798
USP35
ubiquitin specific peptidase 35
chr11_-_63684570 1.047 RCOR2
REST corepressor 2
chr5_-_176037091 1.046 NM_052899
GPRIN1
G protein regulated inducer of neurite outgrowth 1
chr19_-_2721337 1.045 NM_145173
DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr17_+_43325277 1.044 LOC100133991
uncharacterized LOC100133991
chr6_-_99797530 1.043 NM_032511
C6orf168
chromosome 6 open reading frame 168
chr16_-_75529289 1.043


chr22_-_37640187 1.042 RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr20_+_388717 1.041 RBCK1
RanBP-type and C3HC4-type zinc finger containing 1
chr14_-_77965100 1.040 NM_182509
NM_199296
ISM2

isthmin 2 homolog (zebrafish)

chr10_-_103599596 1.040 NM_173194
KCNIP2
Kv channel interacting protein 2
chr6_-_136871542 1.033 MAP7
microtubule-associated protein 7
chr19_-_40971623 1.031 NM_000713
BLVRB
biliverdin reductase B (flavin reductase (NADPH))
chr15_+_90931505 1.026 IQGAP1
IQ motif containing GTPase activating protein 1
chr2_+_112812900 1.025 TMEM87B
transmembrane protein 87B
chr5_-_172756505 1.015 NM_003714
STC2
stanniocalcin 2
chrX_-_118925556 1.012 NM_001000
RPL39
ribosomal protein L39
chr5_+_172484353 1.007 C5orf41
chromosome 5 open reading frame 41
chr22_+_43547558 0.999 TSPO
translocator protein (18kDa)
chr10_+_104155431 0.992 NM_002502
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr5_-_114632240 0.992 NM_001040440
CCDC112
coiled-coil domain containing 112
chr1_-_183559463 0.991 NCF2
neutrophil cytosolic factor 2
chr22_-_42765179 0.991


chr1_+_45140393 0.990 NM_001145636
C1orf228
chromosome 1 open reading frame 228
chr1_+_110753313 0.989 NM_001039574
NM_004978
KCNC4

potassium voltage-gated channel, Shaw-related subfamily, member 4

chr1_+_40506449 0.988 CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr19_+_38794800 0.985 NM_033520
C19orf33
chromosome 19 open reading frame 33
chr1_+_212458774 0.982 PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr1_+_44457231 0.979 NM_152499
CCDC24
coiled-coil domain containing 24
chr9_-_15307325 0.978 NM_001168339
NM_001168340
NM_001168341
NM_152574
TTC39B



tetratricopeptide repeat domain 39B



chr19_-_38878663 0.978 NM_152657
GGN
gametogenetin
chr17_+_28256873 0.977 NM_001145053
EFCAB5
EF-hand calcium binding domain 5
chrX_+_70315637 0.974 NM_001170931
NM_005938
FOXO4

forkhead box O4

chr1_-_168105902 0.969 GPR161
G protein-coupled receptor 161
chr3_-_45267620 0.969 TMEM158
transmembrane protein 158 (gene/pseudogene)
chr2_-_36825234 0.966 NM_001042548
NM_005102
FEZ2

fasciculation and elongation protein zeta 2 (zygin II)

chr2_-_17699705 0.966 NM_001099218
RAD51AP2
RAD51 associated protein 2
chr22_-_38506532 0.966 BAIAP2L2
BAI1-associated protein 2-like 2
chr19_-_52674895 0.965 NM_001102657
ZNF836
zinc finger protein 836
chr20_+_388941 0.962 RBCK1
RanBP-type and C3HC4-type zinc finger containing 1
chr10_-_28591844 0.956 MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr1_+_40506423 0.955 CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr16_+_89642111 0.954 NM_014427
NM_153636
CPNE7

copine VII

chr1_+_44457424 0.952 CCDC24
coiled-coil domain containing 24
chr1_+_40506436 0.951 CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr19_+_17581328 0.951 SLC27A1
solute carrier family 27 (fatty acid transporter), member 1
chr1_-_155881163 0.950 NM_006912
RIT1
Ras-like without CAAX 1
chr1_+_41249479 0.943 NM_004700
NM_172163
KCNQ4

potassium voltage-gated channel, KQT-like subfamily, member 4

chr20_-_4804067 0.942 NM_014737
RASSF2
Ras association (RalGDS/AF-6) domain family member 2
chr12_+_58120029 0.941 LOC100130776
uncharacterized LOC100130776
chr1_+_40506406 0.939 CAP1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr19_-_10679328 0.936 CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr9_+_139377946 0.934 NM_152571
C9orf163
chromosome 9 open reading frame 163
chr2_+_46769892 0.931 RHOQ
ras homolog gene family, member Q
chr12_+_120933911 0.928 DYNLL1
dynein, light chain, LC8-type 1
chr22_+_50354428 0.926 PIM3
pim-3 oncogene
chr12_-_51785400 0.920 GALNT6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
chr4_+_2794811 0.914 SH3BP2
SH3-domain binding protein 2
chr12_+_106696508 0.914 NM_152772
TCP11L2
t-complex 11 (mouse)-like 2
chr15_-_82338459 0.913 MEX3B
mex-3 homolog B (C. elegans)
chr15_+_76352270 0.906 NM_152335
C15orf27
chromosome 15 open reading frame 27
chr1_+_155051263 0.905 NM_004952
EFNA3
ephrin-A3
chr17_-_73874634 0.904 NM_033452
TRIM47
tripartite motif containing 47
chr18_-_500583 0.901 NM_130386
COLEC12
collectin sub-family member 12
chr4_+_84457390 0.897 NM_032717
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr3_+_135684463 0.896 NM_001190447
NM_002718
PPP2R3A

protein phosphatase 2, regulatory subunit B'', alpha

chr20_+_34203746 0.894 NM_003116
SPAG4
sperm associated antigen 4
chr7_-_97501424 0.894 NM_001178077
NM_133436
ASNS

asparagine synthetase (glutamine-hydrolyzing)

chr2_+_46769821 0.892 NM_012249
RHOQ
ras homolog gene family, member Q
chr16_-_67281398 0.888 NM_013241
FHOD1
formin homology 2 domain containing 1
chr19_+_48828820 0.888 EMP3
epithelial membrane protein 3
chr7_+_99775346 0.885 STAG3
stromal antigen 3
chrX_+_117629871 0.882 NM_144658
DOCK11
dedicator of cytokinesis 11
chr3_-_114866090 0.881 NM_015642
ZBTB20
zinc finger and BTB domain containing 20
chr12_-_100378431 0.878 NM_152788
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr6_+_37137882 0.877 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chr1_+_33546700 0.874 NM_052998
ADC
arginine decarboxylase
chr19_-_47104456 0.870 NM_001205281
LOC100506012
serine/threonine-protein phosphatase 5-like
chr22_+_23487512 0.870 NM_004914
RAB36
RAB36, member RAS oncogene family
chr9_+_95858561 0.867 C9orf89
chromosome 9 open reading frame 89
chrX_+_118892544 0.866 NM_001105576
ANKRD58
ankyrin repeat domain 58
chr15_+_69591272 0.863 NM_017705
PAQR5
progestin and adipoQ receptor family member V
chr8_+_124428964 0.863 NM_018024
WDYHV1
WDYHV motif containing 1
chr17_-_41910439 0.863 NM_001932
MPP3
membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
chr2_+_207308280 0.860 NM_003812
ADAM23
ADAM metallopeptidase domain 23
chr1_-_183560010 0.860 NM_001127651
NCF2
neutrophil cytosolic factor 2
chr1_-_11714471 0.860 FBXO2
F-box protein 2
chr4_+_2794712 0.856 NM_001122681
SH3BP2
SH3-domain binding protein 2
chr17_-_27949814 0.855 CORO6
coronin 6

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.