Motif ID: NFE2L1.p2

Z-value: 2.266


Transcription factors associated with NFE2L1.p2:

Gene SymbolEntrez IDGene Name
NFE2L1 4779 nuclear factor (erythroid-derived 2)-like 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NFE2L1hg19_v1_chr17_+_46125675_46125723-0.128.1e-01Click!


Activity profile for motif NFE2L1.p2.

activity profile for motif NFE2L1.p2


Sorted Z-values histogram for motif NFE2L1.p2

Sorted Z-values for motif NFE2L1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFE2L1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_92681025 3.513 NM_014391
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr10_-_92680784 3.234 ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr4_+_74606222 2.731 NM_000584
IL8
interleukin 8
chr17_+_17398334 2.697


chr12_-_123201319 2.557 NM_006018
HCAR3
hydroxycarboxylic acid receptor 3
chr12_-_10324675 1.975 NM_001172632
NM_001172633
NM_002543
OLR1


oxidized low density lipoprotein (lectin-like) receptor 1


chr17_+_57915192 1.798


chr1_+_170115187 1.562 NM_001136107
METTL11B
methyltransferase like 11B
chr11_+_124439892 1.440 NM_001005194
OR8A1
olfactory receptor, family 8, subfamily A, member 1
chr2_-_106015423 1.337 NM_001039492
NM_001450
NM_201555
FHL2


four and a half LIM domains 2


chr2_+_210444364 1.334 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr3_-_151987332 1.159 LOC401093
uncharacterized LOC401093
chrX_+_142967172 1.151 NM_001012989
UBE2NL
ubiquitin-conjugating enzyme E2N-like
chr2_+_210444154 1.104 MAP2
microtubule-associated protein 2
chr7_+_123249076 1.081 NM_080928
ASB15
ankyrin repeat and SOCS box containing 15
chr6_-_88854989 1.061 NM_033181
CNR1
cannabinoid receptor 1 (brain)
chr15_-_40398286 1.049 NM_001003942
NM_001003943
BMF

Bcl2 modifying factor

chr1_+_174843523 1.002 NM_001243763
RABGAP1L
RAB GTPase activating protein 1-like
chr5_+_174151531 0.963 NM_002449
MSX2
msh homeobox 2
chr3_-_112359962 0.953 NM_199511
NM_199512
CCDC80

coiled-coil domain containing 80

chr4_-_105412466 0.939 NM_025212
CXXC4
CXXC finger protein 4
chr12_-_123187842 0.931 NM_177551
HCAR2
hydroxycarboxylic acid receptor 2
chr6_-_31648140 0.917 NM_025262
LY6G5C
lymphocyte antigen 6 complex, locus G5C
chr1_+_149858466 0.916 NM_003517
HIST2H2AC
histone cluster 2, H2ac
chr17_+_4802866 0.904 NM_001145536
C17orf107
chromosome 17 open reading frame 107
chr2_+_27719702 0.893 NM_001486
GCKR
glucokinase (hexokinase 4) regulator
chr4_+_74735107 0.892 NM_001511
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr4_+_88896899 0.884 SPP1
secreted phosphoprotein 1
chr1_-_59248287 0.876 JUN
jun proto-oncogene
chr7_+_143701021 0.831 NM_001005281
OR6B1
olfactory receptor, family 6, subfamily B, member 1
chr15_-_40398573 0.814 NM_033503
BMF
Bcl2 modifying factor
chr17_-_79478956 0.786 ACTG1
actin, gamma 1
chr2_+_201473942 0.776 AOX1
aldehyde oxidase 1
chr3_+_42977833 0.760 NM_001205272
KRBOX1
KRAB box domain containing 1
chr11_-_18258315 0.756 SAA4
serum amyloid A4, constitutive
chr15_+_90895476 0.756 NM_001004309
ZNF774
zinc finger protein 774
chr1_-_178062734 0.746 LOC100302401
uncharacterized LOC100302401
chr4_+_88571453 0.738 NM_001079911
NM_004407
DMP1

dentin matrix acidic phosphoprotein 1

chr9_-_139981102 0.734 LOC100289341
uncharacterized LOC100289341
chr17_-_42081836 0.733 NM_004160
PYY
peptide YY
chr2_-_192711651 0.733 SDPR
serum deprivation response
chr11_-_87908551 0.728 NM_022337
RAB38
RAB38, member RAS oncogene family
chr4_+_88896868 0.714 SPP1
secreted phosphoprotein 1
chr13_+_24144402 0.704 NM_001204459
NM_148957
TNFRSF19

tumor necrosis factor receptor superfamily, member 19

chr11_-_65337743 0.694 LOC254100
uncharacterized LOC254100
chr12_-_15114495 0.694 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr7_+_116660291 0.693 ST7
suppression of tumorigenicity 7
chr5_-_90610218 0.692 LOC100505994
uncharacterized LOC100505994
chrX_-_24690740 0.692 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr17_+_77704881 0.691 NM_178543
ENPP7
ectonucleotide pyrophosphatase/phosphodiesterase 7
chr8_-_82607206 0.681 NM_001010893
SLC10A5
solute carrier family 10 (sodium/bile acid cotransporter family), member 5
chr4_+_88896838 0.680 SPP1
secreted phosphoprotein 1
chr17_-_17399494 0.675 NM_001199989
NM_016084
RASD1

RAS, dexamethasone-induced 1

chr4_+_75230856 0.675 NM_001432
EREG
epiregulin
chr6_-_46293215 0.645 RCAN2
regulator of calcineurin 2
chr3_-_112359863 0.643 CCDC80
coiled-coil domain containing 80
chr5_-_115910406 0.640 NM_020796
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chrM_+_5245 0.633


chr4_-_170077807 0.625 SH3RF1
SH3 domain containing ring finger 1
chr16_-_54962707 0.614 CRNDE
colorectal neoplasia differentially expressed (non-protein coding)
chr1_+_31191612 0.614 LOC100129196
uncharacterized LOC100129196
chr4_+_88896801 0.613 NM_000582
NM_001040058
NM_001040060
NM_001251829
NM_001251830
SPP1




secreted phosphoprotein 1




chr11_-_124190092 0.603 NM_001002918
OR8D2
olfactory receptor, family 8, subfamily D, member 2
chr1_+_65730423 0.601 NM_014787
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr14_+_21156922 0.594 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr12_+_12938540 0.578 NM_030817
APOLD1
apolipoprotein L domain containing 1
chr14_-_50862616 0.577 NM_004196
CDKL1
cyclin-dependent kinase-like 1 (CDC2-related kinase)
chr5_-_75919051 0.573 NM_004101
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr2_-_218843541 0.571 TNS1
tensin 1
chr7_-_5568823 0.566 ACTB
actin, beta
chr2_+_169659099 0.564 NM_001039724
NM_001171632
NM_052946
NOSTRIN


nitric oxide synthase trafficker


chr6_+_12290528 0.563 NM_001168319
NM_001955
EDN1

endothelin 1

chrM_+_4770 0.561


chr7_+_128312345 0.559 NM_001012454
NM_001128926
FAM71F2

family with sequence similarity 71, member F2

chr4_-_39523132 0.554 UGDH
UDP-glucose 6-dehydrogenase
chr4_-_70080448 0.548 NM_001073
UGT2B11
UGT2B10
UDP glucuronosyltransferase 2 family, polypeptide B11
UDP glucuronosyltransferase 2 family, polypeptide B10
chr21_-_27253197 0.546 APP
amyloid beta (A4) precursor protein
chr2_-_70189396 0.536 NM_152792
ASPRV1
aspartic peptidase, retroviral-like 1
chr1_+_51435911 0.535 CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr12_+_53491448 0.533 IGFBP6
insulin-like growth factor binding protein 6
chr1_+_32050510 0.525 TINAGL1
tubulointerstitial nephritis antigen-like 1
chr3_-_12200339 0.524 TIMP4
TIMP metallopeptidase inhibitor 4
chrX_+_37892786 0.524 NM_001163334
SYTL5
synaptotagmin-like 5
chr6_+_84222252 0.523 PRSS35
protease, serine, 35
chr12_+_7169192 0.523


chr3_-_170744458 0.520 SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chr7_-_5569200 0.517 ACTB
actin, beta
chr18_-_59560303 0.517 NM_173557
RNF152
ring finger protein 152
chr9_+_92219926 0.509 NM_006705
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr2_-_27616443 0.509 FTH1P3
ferritin, heavy polypeptide 1 pseudogene 3
chr4_+_184827882 0.501


chr10_-_14879967 0.500 NM_001029954
CDNF
cerebral dopamine neurotrophic factor
chr7_-_41742666 0.497 NM_002192
INHBA
inhibin, beta A
chr17_-_7493389 0.495 NM_006942
SOX15
SRY (sex determining region Y)-box 15
chr10_+_81065875 0.493 ZMIZ1
zinc finger, MIZ-type containing 1
chr9_-_85882093 0.490 NM_001244962
FRMD3
FERM domain containing 3
chr14_-_21945031 0.487 NM_032846
RAB2B
RAB2B, member RAS oncogene family
chr16_-_31021716 0.486 NM_052874
STX1B
syntaxin 1B
chr17_+_40274755 0.481 NM_033194
HSPB9
heat shock protein, alpha-crystallin-related, B9
chr11_-_71814268 0.481 LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chr15_-_72490109 0.479 NM_001012642
GRAMD2
GRAM domain containing 2
chr11_-_108464344 0.478 NM_015065
EXPH5
exophilin 5
chr14_+_105953531 0.472 CRIP1
cysteine-rich protein 1 (intestinal)
chr9_-_14313899 0.471 NFIB
nuclear factor I/B
chr17_-_79478236 0.471 ACTG1
actin, gamma 1
chr19_-_18392048 0.461 JUND
jun D proto-oncogene
chr12_+_90103470 0.459 LOC338758
uncharacterized LOC338758
chrX_-_115594136 0.457 NM_001017978
CXorf61
chromosome X open reading frame 61
chr17_-_7760740 0.453 LSMD1
LSM domain containing 1
chr12_-_105322056 0.453 NM_032148
SLC41A2
solute carrier family 41, member 2
chr2_-_218867677 0.452 TNS1
tensin 1
chr17_+_7482804 0.452 NM_001251
NM_001040059
CD68

CD68 molecule

chr8_+_9953061 0.451 NM_001135671
NM_001199729
MSRA

methionine sulfoxide reductase A

chr7_+_73245192 0.450 NM_001305
CLDN4
claudin 4
chr3_+_25470067 0.447 RARB
retinoic acid receptor, beta
chr1_-_23885916 0.443 ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr11_-_64856541 0.438 NM_001242631
LOC100130348
LOC399904
uncharacterized LOC100130348
uncharacterized LOC399904
chr3_+_119501556 0.437 NM_022002
NR1I2
nuclear receptor subfamily 1, group I, member 2
chr9_-_14313509 0.434 NFIB
nuclear factor I/B
chr16_+_2653350 0.434 LOC652276
potassium channel tetramerisation domain containing 5 pseudogene
chr2_-_25194484 0.433 DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr7_+_28725597 0.433 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr14_+_93118793 0.430 RIN3
Ras and Rab interactor 3
chr7_+_143657019 0.429 NM_012369
OR2F1
olfactory receptor, family 2, subfamily F, member 1
chr2_+_189839132 0.427 COL3A1
collagen, type III, alpha 1
chr16_-_72991648 0.424 ZFHX3
zinc finger homeobox 3
chr17_-_39093671 0.424 NM_015515
KRT23
keratin 23 (histone deacetylase inducible)
chr11_-_46717657 0.418 ARHGAP1
Rho GTPase activating protein 1
chrM_-_9203 0.418


chrX_-_105282714 0.416 NM_000354
SERPINA7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr17_-_48207113 0.415 NM_174920
SAMD14
sterile alpha motif domain containing 14
chr15_-_72612247 0.413 NM_001172684
CELF6
CUGBP, Elav-like family member 6
chr17_-_39684585 0.411 NM_002276
KRT19
keratin 19
chr15_+_42651697 0.411 NM_000070
NM_024344
NM_173087
CAPN3


calpain 3, (p94)


chr2_-_190445466 0.408 SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr4_+_72204769 0.405 NM_003759
SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr17_-_39684499 0.405 KRT19
keratin 19
chr14_+_51026742 0.403 NM_015915
NM_181598
ATL1

atlastin GTPase 1

chr2_-_190445612 0.402 SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr7_+_116660263 0.402 ST7
suppression of tumorigenicity 7
chr3_-_52488030 0.400 NM_003280
TNNC1
troponin C type 1 (slow)
chrM_+_7380 0.400


chr11_-_10590078 0.400 NM_006691
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chrX_-_112066353 0.398 NM_001113490
AMOT
angiomotin
chr4_+_184827805 0.397 STOX2
storkhead box 2
chrX_+_100224696 0.395 NM_001012990
NM_001162490
NM_001162491
ARL13A


ADP-ribosylation factor-like 13A


chr4_+_69681709 0.390 NM_001075
NM_001144767
UGT2B10

UDP glucuronosyltransferase 2 family, polypeptide B10

chr1_+_201979689 0.388 NM_001114309
NM_004433
ELF3

E74-like factor 3 (ets domain transcription factor, epithelial-specific )

chr6_-_37467621 0.388 CCDC167
coiled-coil domain containing 167
chr1_-_57431620 0.388 NM_000066
C8B
complement component 8, beta polypeptide
chr1_+_50574589 0.387 NM_001144774
NM_021952
ELAVL4

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)

chr14_-_57960432 0.381 NM_018168
C14orf105
chromosome 14 open reading frame 105
chr2_+_29038862 0.375 NM_001008779
SPDYA
speedy homolog A (Xenopus laevis)
chr4_-_70725792 0.374 NM_005420
SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
chr17_+_59477473 0.373 TBX2
T-box 2
chr9_-_100684770 0.371 NM_016481
C9orf156
chromosome 9 open reading frame 156
chr2_+_177028804 0.371 NM_006898
HOXD3
homeobox D3
chr1_-_156786500 0.370 NM_001161441
NM_001161442
NM_001161444
NM_003975
SH2D2A



SH2 domain containing 2A



chr21_-_31852631 0.369 NM_181607
KRTAP19-1
keratin associated protein 19-1
chr2_-_190445521 0.368 NM_014585
SLC40A1
solute carrier family 40 (iron-regulated transporter), member 1
chr1_-_200377262 0.366 ZNF281
zinc finger protein 281
chr1_+_201979747 0.363 ELF3
E74-like factor 3 (ets domain transcription factor, epithelial-specific )
chr5_+_140501579 0.363 NM_018938
PCDHB4
protocadherin beta 4
chr16_-_21436657 0.363 NM_130464
NPIPL3
nuclear pore complex interacting protein-like 3
chr6_+_170151711 0.362 NM_018341
C6orf70
chromosome 6 open reading frame 70
chr12_-_123214882 0.362 NM_032554
HCAR1
hydroxycarboxylic acid receptor 1
chr1_-_173793454 0.362 CENPL
centromere protein L
chr6_-_76203256 0.362 NM_015687
FILIP1
filamin A interacting protein 1
chr22_+_51041561 0.361 NM_016431
MAPK8IP2
mitogen-activated protein kinase 8 interacting protein 2
chr18_-_53068942 0.360


chrX_-_32430370 0.360 NM_004011
NM_004012
DMD

dystrophin

chrX_+_149613719 0.360 NM_001177466
NM_005491
MAMLD1

mastermind-like domain containing 1

chr21_-_36421195 0.360 RUNX1
runt-related transcription factor 1
chr1_-_221915393 0.359 DUSP10
dual specificity phosphatase 10
chr1_-_221915426 0.359 DUSP10
dual specificity phosphatase 10
chr7_+_117120016 0.358 NM_000492
CFTR
cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7)
chr1_+_50569581 0.358 NM_001144776
ELAVL4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr19_-_15590203 0.357 NM_052890
PGLYRP2
peptidoglycan recognition protein 2
chr1_+_110655061 0.357 NM_203412
UBL4B
ubiquitin-like 4B
chr6_-_26027479 0.356 NM_003544
HIST1H4B
histone cluster 1, H4b
chr8_+_126104082 0.356 NM_173685
NSMCE2
non-SMC element 2, MMS21 homolog (S. cerevisiae)
chr6_-_37467688 0.356 NM_138493
CCDC167
coiled-coil domain containing 167
chr2_+_70142303 0.353 MXD1
MAX dimerization protein 1
chr6_+_143929316 0.352 NM_001100166
NM_014721
PHACTR2

phosphatase and actin regulator 2

chr16_+_54319508 0.351


chr11_-_71814294 0.350 LAMTOR1
late endosomal/lysosomal adaptor, MAPK and MTOR activator 1
chrX_-_129519420 0.348 NM_178471
GPR119
G protein-coupled receptor 119
chr19_+_8478181 0.348 NM_001005415
NM_001005416
NM_016496
MARCH2


membrane-associated ring finger (C3HC4) 2


chr15_+_66994669 0.347 NM_005585
SMAD6
SMAD family member 6
chr5_-_145483877 0.347 NM_001029869
PLAC8L1
PLAC8-like 1
chr17_+_7482938 0.345 CD68
CD68 molecule
chr1_+_202091971 0.345 NM_004767
GPR37L1
G protein-coupled receptor 37 like 1
chr14_-_21944826 0.344 NM_001163380
RAB2B
RAB2B, member RAS oncogene family
chr17_+_7461591 0.344 NM_001198622
NM_001198623
NM_001198624
NM_003808
NM_172087
NM_172088
TNFSF13





tumor necrosis factor (ligand) superfamily, member 13





chrX_+_28605558 0.341 NM_014271
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr8_-_37727937 0.341 RAB11FIP1
RAB11 family interacting protein 1 (class I)
chrX_+_107069081 0.340 NM_012216
NM_052817
MID2

midline 2

chr12_-_11002051 0.338 NM_001098538
NM_007244
PRR4

proline rich 4 (lacrimal)

chr3_-_47933997 0.338 MAP4
microtubule-associated protein 4
chrX_+_133941204 0.337 NM_001170782
NM_001170784
NM_001170779
NM_001170781
NM_001170783
NM_138819
FAM122C





family with sequence similarity 122C






Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
54.20 2.03e-02 GO:0031674 I band

Nothing significant found in function category.