Motif ID: NR5A1,2.p2

Z-value: 1.939


Transcription factors associated with NR5A1,2.p2:

Gene SymbolEntrez IDGene Name
NR5A1 2516 nuclear receptor subfamily 5, group A, member 1
NR5A2 2494 nuclear receptor subfamily 5, group A, member 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
NR5A2hg19_v1_chr1_+_199996729_199997010-0.394.5e-01Click!


Activity profile for motif NR5A1,2.p2.

activity profile for motif NR5A1,2.p2


Sorted Z-values histogram for motif NR5A1,2.p2

Sorted Z-values for motif NR5A1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NR5A1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_-_44516237 0.890 NM_080608
SPATA25
spermatogenesis associated 25
chr6_-_27775683 0.883 NM_003519
HIST1H2BL
histone cluster 1, H2bl
chr6_+_27833033 0.879 NM_003511
HIST1H2AI
HIST1H2AL
histone cluster 1, H2ai
histone cluster 1, H2al
chr4_+_110772485 0.792 NM_198506
LRIT3
leucine-rich repeat, immunoglobulin-like and transmembrane domains 3
chr6_-_87804773 0.784 NM_000735
NM_001252383
CGA

glycoprotein hormones, alpha polypeptide

chr1_+_155147051 0.726 TRIM46
tripartite motif containing 46
chr19_+_2249112 0.698 NM_000479
AMH
anti-Mullerian hormone
chr17_-_7832752 0.664 NM_004732
KCNAB3
potassium voltage-gated channel, shaker-related subfamily, beta member 3
chr3_+_50229022 0.640 NM_000172
NM_144499
GNAT1

guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 1

chr22_+_32010152 0.636 SFI1
Sfi1 homolog, spindle assembly associated (yeast)
chr6_+_27775898 0.623 NM_003509
HIST1H2AI
HIST1H2AM
HIST1H3F
histone cluster 1, H2ai
histone cluster 1, H2am
histone cluster 1, H3f
chr22_+_31518923 0.618 NM_001002837
INPP5J
inositol polyphosphate-5-phosphatase J
chr6_+_27861202 0.593 NM_003527
HIST1H2BO
histone cluster 1, H2bo
chr15_-_83621350 0.580 NM_004839
NM_199330
HOMER2

homer homolog 2 (Drosophila)

chr8_-_17658711 0.573


chr7_-_16505292 0.570 NM_015464
SOSTDC1
sclerostin domain containing 1
chr1_+_16330730 0.534 NM_178840
C1orf64
chromosome 1 open reading frame 64
chr19_-_50143350 0.530 NM_006270
RRAS
related RAS viral (r-ras) oncogene homolog
chr6_-_26043884 0.528 NM_021062
HIST1H2BB
histone cluster 1, H2bb
chr20_-_633808 0.528 SRXN1
sulfiredoxin 1
chr10_+_99344421 0.516 HOGA1
4-hydroxy-2-oxoglutarate aldolase 1
chr11_+_7506599 0.514 NM_198474
OLFML1
olfactomedin-like 1
chr14_+_24782312 0.510 NM_181657
LTB4R
leukotriene B4 receptor
chr14_+_77228940 0.500 VASH1
vasohibin 1
chr14_-_105261850 0.493 AKT1
v-akt murine thymoma viral oncogene homolog 1
chr3_+_186358148 0.474 NM_014375
FETUB
fetuin B
chr20_-_633844 0.460 NM_080725
SRXN1
sulfiredoxin 1
chr3_-_49726081 0.459 NM_020998
MST1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr22_+_35779103 0.456 HMOX1
heme oxygenase (decycling) 1
chr16_+_776957 0.452 NM_032304
HAGHL
hydroxyacylglutathione hydrolase-like
chr5_+_87564729 0.448 LOC100505894
uncharacterized LOC100505894
chr16_-_67223998 0.443 NM_178516
EXOC3L1
exocyst complex component 3-like 1
chr19_-_14016908 0.439 NM_024323
C19orf57
chromosome 19 open reading frame 57
chr22_+_42372763 0.436 NM_019106
NM_145733
SEPT3

septin 3

chr18_-_74728963 0.436 MBP
myelin basic protein
chr1_+_2518071 0.430 NM_001195736
NM_001195737
NM_001195738
NM_001195740
NM_001195741
NM_152371
FAM213B





family with sequence similarity 213, member B





chr12_-_26277807 0.428 NM_030762
BHLHE41
basic helix-loop-helix family, member e41
chr1_+_149858466 0.422 NM_003517
HIST2H2AC
histone cluster 2, H2ac
chr5_+_87564840 0.421 LOC100505894
uncharacterized LOC100505894
chr5_-_139725860 0.415 HBEGF
heparin-binding EGF-like growth factor
chr12_-_58159386 0.414 CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr12_+_53818864 0.406 AMHR2
anti-Mullerian hormone receptor, type II
chr22_+_51176623 0.406 NM_001097
ACR
acrosin
chr1_-_111743080 0.405


chr18_+_616671 0.404 NM_199167
CLUL1
clusterin-like 1 (retinal)
chr8_+_92114846 0.402 NM_001129890
LRRC69
leucine rich repeat containing 69
chr8_+_144349564 0.402 NM_138465
GLI4
GLI family zinc finger 4
chr9_+_139846767 0.400 NM_178536
LCN12
lipocalin 12
chr9_+_126773851 0.397 NM_004789
LHX2
LIM homeobox 2
chr4_+_41614911 0.394 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr1_+_206224282 0.389 NM_000707
AVPR1B
arginine vasopressin receptor 1B
chr2_+_74741565 0.387 NM_016170
TLX2
T-cell leukemia homeobox 2
chr6_-_135271206 0.387 NM_001193480
NM_022568
NM_170771
ALDH8A1


aldehyde dehydrogenase 8 family, member A1


chr20_+_35504514 0.384 NM_080628
C20orf118
chromosome 20 open reading frame 118
chr6_-_31138180 0.381 NM_002701
POU5F1
POU5F1B
POU5F1P3
POU5F1P4
POU class 5 homeobox 1
POU class 5 homeobox 1B
POU class 5 homeobox 1 pseudogene 3
POU class 5 homeobox 1 pseudogene 4
chr11_+_63993720 0.380 NM_001128612
NM_001128613
NM_032344
NUDT22


nudix (nucleoside diphosphate linked moiety X)-type motif 22


chr22_-_37505602 0.379 TMPRSS6
transmembrane protease, serine 6
chr9_+_135937364 0.379 NM_001807
CEL
carboxyl ester lipase (bile salt-stimulated lipase)
chr16_-_4665002 0.374 FAM100A
family with sequence similarity 100, member A
chr20_+_57264186 0.374 NM_001204872
NM_001204873
NPEPL1

aminopeptidase-like 1

chr5_+_94955979 0.370 NM_199243
GPR150
G protein-coupled receptor 150
chr1_-_1590403 0.369 CDK11A
CDK11B
cyclin-dependent kinase 11A
cyclin-dependent kinase 11B
chr18_-_658246 0.364 NM_001012716
C18orf56
chromosome 18 open reading frame 56
chr17_-_36760864 0.364 SRCIN1
SRC kinase signaling inhibitor 1
chr6_-_53013581 0.362 NM_003643
GCM1
glial cells missing homolog 1 (Drosophila)
chr22_-_39240016 0.361 NM_014293
NPTXR
neuronal pentraxin receptor
chr10_-_18948166 0.361


chr22_-_39640956 0.358 NM_002608
PDGFB
platelet-derived growth factor beta polypeptide
chr2_+_71295685 0.357 NAGK
N-acetylglucosamine kinase
chr6_-_42162693 0.356 NM_002098
GUCA1B
guanylate cyclase activator 1B (retina)
chr5_-_27038650 0.355 NM_016279
CDH9
cadherin 9, type 2 (T1-cadherin)
chr7_+_128312345 0.354 NM_001012454
NM_001128926
FAM71F2

family with sequence similarity 71, member F2

chr6_+_17282931 0.351 NM_153020
RBM24
RNA binding motif protein 24
chr21_+_45719953 0.350 PFKL
phosphofructokinase, liver
chr16_-_58328879 0.350 NM_001080492
PRSS54
protease, serine, 54
chr20_-_42815732 0.346 JPH2
junctophilin 2
chr10_-_50970321 0.346 NM_001143996
NM_001143997
NM_018245
OGDHL


oxoglutarate dehydrogenase-like


chr5_-_139943829 0.344 APBB3
amyloid beta (A4) precursor protein-binding, family B, member 3
chr1_-_148176392 0.343


chr22_+_42486904 0.342 LOC100132273
uncharacterized LOC100132273
chr19_+_46171501 0.341 NM_000164
GIPR
gastric inhibitory polypeptide receptor
chr2_+_233320832 0.340 NM_001631
ALPI
alkaline phosphatase, intestinal
chr2_+_27505296 0.337 NM_032546
NM_187841
TRIM54

tripartite motif containing 54

chr2_+_177016112 0.335 NM_014621
HOXD4
homeobox D4
chr16_+_57481336 0.335 NM_020312
COQ9
coenzyme Q9 homolog (S. cerevisiae)
chr1_+_157963310 0.333 KIRREL
kin of IRRE like (Drosophila)
chr12_-_49177876 0.333 NM_015270
ADCY6
adenylate cyclase 6
chr3_+_186383770 0.333 NM_000412
HRG
histidine-rich glycoprotein
chr1_-_111743261 0.332 NM_024901
DENND2D
DENN/MADD domain containing 2D
chr11_+_73359734 0.330 NM_001130036
PLEKHB1
pleckstrin homology domain containing, family B (evectins) member 1
chr16_+_83986826 0.326 NM_182981
OSGIN1
oxidative stress induced growth inhibitor 1
chr8_-_145754389 0.321 NM_001001795
C8orf82
chromosome 8 open reading frame 82
chr15_-_91475653 0.321 NM_198527
HDDC3
HD domain containing 3
chr22_+_45680827 0.321 NM_001167574
NM_006953
UPK3A

uroplakin 3A

chr18_-_74729049 0.320 NM_001025081
NM_001025090
NM_001025092
NM_002385
MBP



myelin basic protein



chr13_-_33859835 0.318 NM_178006
STARD13
StAR-related lipid transfer (START) domain containing 13
chr2_-_27712520 0.317 NM_015662
IFT172
intraflagellar transport 172 homolog (Chlamydomonas)
chr3_-_15563160 0.317 NM_005677
NM_080539
COLQ

collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase

chr3_-_12200339 0.315 TIMP4
TIMP metallopeptidase inhibitor 4
chr17_+_48049678 0.315 DLX4
distal-less homeobox 4
chr10_-_101380217 0.311 NM_031212
SLC25A28
solute carrier family 25, member 28
chr2_+_103378489 0.308 NM_144632
TMEM182
transmembrane protein 182
chr22_+_44422183 0.308 NM_001243386
PARVB
parvin, beta
chr11_-_6633400 0.306 TAF10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr1_-_20126368 0.306 NM_181719
TMCO4
transmembrane and coiled-coil domains 4
chr7_+_123249076 0.304 NM_080928
ASB15
ankyrin repeat and SOCS box containing 15
chr6_+_35181721 0.303 SCUBE3
signal peptide, CUB domain, EGF-like 3
chr19_-_36643770 0.302 NM_001864
COX7A1
cytochrome c oxidase subunit VIIa polypeptide 1 (muscle)
chr13_+_23755059 0.301 NM_000231
SGCG
sarcoglycan, gamma (35kDa dystrophin-associated glycoprotein)
chr15_-_95870310 0.300 LOC400456
uncharacterized LOC400456
chr12_+_122516676 0.300 MLXIP
MLX interacting protein
chrX_+_100474932 0.297 NM_001171184
NM_001939
DRP2

dystrophin related protein 2

chr12_+_52306112 0.296 NM_001077401
ACVRL1
activin A receptor type II-like 1
chr9_+_214816 0.295 DOCK8
dedicator of cytokinesis 8
chr3_-_49460110 0.294 NM_000481
NM_001164710
NM_001164711
NM_001164712
AMT



aminomethyltransferase



chr11_-_16424391 0.292 NM_001145819
NM_017508
SOX6

SRY (sex determining region Y)-box 6

chr11_-_6633428 0.288 NM_006284
TAF10
TAF10 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 30kDa
chr12_-_772525 0.288 NM_016533
NINJ2
ninjurin 2
chr1_+_171217632 0.287 NM_002021
FMO1
flavin containing monooxygenase 1
chr11_-_63933204 0.287 MACROD1
MACRO domain containing 1
chr3_-_15106806 0.286 NM_022497
MRPS25
mitochondrial ribosomal protein S25
chrX_+_36065052 0.285 NM_173695
CXorf59
chromosome X open reading frame 59
chr17_-_38256548 0.284 NR1D1
nuclear receptor subfamily 1, group D, member 1
chr14_+_94577078 0.282 NM_001130080
NM_005532
IFI27

interferon, alpha-inducible protein 27

chr6_+_31868775 0.281 NM_001178063
C2
complement component 2
chr5_+_121465214 0.280 NM_207317
ZNF474
zinc finger protein 474
chr22_-_37499456 0.280 NM_153609
TMPRSS6
transmembrane protease, serine 6
chr19_-_13044459 0.279 FARSA
phenylalanyl-tRNA synthetase, alpha subunit
chr11_-_67141647 0.277 NM_001166212
CLCF1
cardiotrophin-like cytokine factor 1
chr6_+_27114860 0.276 NM_080596
HIST1H2AH
histone cluster 1, H2ah
chr1_+_6684924 0.276 NM_001195753
THAP3
THAP domain containing, apoptosis associated protein 3
chr20_+_43211219 0.275 PKIG
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr10_+_115310589 0.275 NM_001177660
HABP2
hyaluronan binding protein 2
chr7_+_102553343 0.271 NM_001031692
NM_005824
LRRC17

leucine rich repeat containing 17

chr5_-_11903964 0.270 NM_001332
CTNND2
catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)
chr17_+_74463629 0.269 NM_001088
AANAT
aralkylamine N-acetyltransferase
chr14_-_24037266 0.269 NM_003917
AP1G2
adaptor-related protein complex 1, gamma 2 subunit
chr11_+_45907046 0.268 NM_005456
MAPK8IP1
mitogen-activated protein kinase 8 interacting protein 1
chr1_+_33546700 0.268 NM_052998
ADC
arginine decarboxylase
chr6_-_31550065 0.267 NM_002341
NM_009588
LTB

lymphotoxin beta (TNF superfamily, member 3)

chr12_+_93963597 0.266 NM_003877
SOCS2
suppressor of cytokine signaling 2
chr22_-_38966066 0.266 NM_007068
DMC1
DMC1 dosage suppressor of mck1 homolog, meiosis-specific homologous recombination (yeast)
chr17_-_27948345 0.263 NM_032854
CORO6
coronin 6
chr1_+_19923457 0.263 NM_001204088
NM_001204089
NM_001032363
NM_001204082
NM_001204083
C1orf151-NBL1

MINOS1


C1orf151-NBL1 readthrough

mitochondrial inner membrane organizing system 1


chr17_-_8063946 0.262 VAMP2
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr6_+_35182182 0.262 NM_152753
SCUBE3
signal peptide, CUB domain, EGF-like 3
chr5_-_72744351 0.262 NM_004472
FOXD1
forkhead box D1
chr7_-_98805088 0.261 NM_001145715
KPNA7
karyopherin alpha 7 (importin alpha 8)
chr4_+_187187342 0.260 F11
coagulation factor XI
chr9_+_3526047 0.259


chr6_-_43027114 0.259 NM_015950
MRPL2
mitochondrial ribosomal protein L2
chr6_+_35265594 0.257 NM_022047
DEF6
differentially expressed in FDCP 6 homolog (mouse)
chr9_-_138391696 0.257 NM_001048265
NM_144654
C9orf116

chromosome 9 open reading frame 116

chr17_+_46970128 0.256 NM_001002027
NM_005175
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr2_+_12858363 0.256


chr6_+_43738757 0.255 VEGFA
vascular endothelial growth factor A
chr17_-_17485744 0.253 NM_007169
PEMT
phosphatidylethanolamine N-methyltransferase
chr22_+_45072687 0.253 NM_001017530
NM_001198721
NM_015366
PRR5


proline rich 5 (renal)


chr7_-_131241321 0.253 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr19_-_19049790 0.251 NM_001145724
HOMER3
homer homolog 3 (Drosophila)
chr11_+_67007488 0.251 KDM2A
lysine (K)-specific demethylase 2A
chr22_-_39636906 0.250 NM_033016
PDGFB
platelet-derived growth factor beta polypeptide
chr1_+_156561594 0.250


chr12_-_56756526 0.248 NM_001638
APOF
apolipoprotein F
chr12_-_117537090 0.247 NM_001168325
NM_017899
TESC

tescalcin

chr12_+_120875891 0.246 NM_004373
COX6A1
cytochrome c oxidase subunit VIa polypeptide 1
chr5_+_176794312 0.246 RGS14
regulator of G-protein signaling 14
chr2_-_25194772 0.246 NM_001198559
NM_016544
DNAJC27

DnaJ (Hsp40) homolog, subfamily C, member 27

chr5_-_149535138 0.245 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr1_+_70820485 0.244 NM_001031693
NM_001036645
NM_001036646
HHLA3


HERV-H LTR-associating 3


chr3_-_10547221 0.244 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr16_+_67233013 0.243 NM_024712
ELMO3
engulfment and cell motility 3
chr4_+_41614933 0.243 LIMCH1
LIM and calponin homology domains 1
chr5_-_149535420 0.241 NM_002609
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr16_-_4852571 0.241 NM_024589
ROGDI
rogdi homolog (Drosophila)
chr11_+_63706433 0.240 NM_024771
NAA40
N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae)
chr17_+_900329 0.240 NM_013337
TIMM22
translocase of inner mitochondrial membrane 22 homolog (yeast)
chr9_+_131038421 0.239 NM_001040011
SWI5
SWI5 recombination repair homolog (yeast)
chr2_-_26541916 0.238 NM_001145168
NM_001145169
GPR113

G protein-coupled receptor 113

chr5_-_131347518 0.238 NM_001205248
NM_001205251
NM_001205250
ACSL6


acyl-CoA synthetase long-chain family member 6


chr1_+_64239566 0.237 NM_001083592
NM_005012
ROR1

receptor tyrosine kinase-like orphan receptor 1

chr6_+_43266008 0.237 SLC22A7
solute carrier family 22 (organic anion transporter), member 7
chr11_+_77899857 0.237 NM_020798
USP35
ubiquitin specific peptidase 35
chr2_-_26569610 0.236 NM_153835
GPR113
G protein-coupled receptor 113
chr19_-_13044528 0.235 NM_004461
FARSA
phenylalanyl-tRNA synthetase, alpha subunit
chr19_-_47735858 0.235 NM_001127240
NM_001127241
NM_001127242
BBC3


BCL2 binding component 3


chr2_-_192711651 0.235 SDPR
serum deprivation response
chr17_-_45899133 0.233 NM_145798
OSBPL7
oxysterol binding protein-like 7
chr14_+_105267378 0.232 ZBTB42
zinc finger and BTB domain containing 42
chr10_-_101190201 0.232 NM_002079
GOT1
glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)
chrX_+_119738542 0.231 NM_001137554
MCTS1
malignant T cell amplified sequence 1
chr10_-_101380160 0.230 SLC25A28
solute carrier family 25, member 28
chr15_-_75932509 0.230 NM_018285
IMP3
IMP3, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr14_-_24616429 0.229 PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr19_-_15590203 0.227 NM_052890
PGLYRP2
peptidoglycan recognition protein 2
chr22_+_45072936 0.226 PRR5
proline rich 5 (renal)
chr9_+_134165075 0.226 NM_032728
PPAPDC3
phosphatidic acid phosphatase type 2 domain containing 3
chr13_+_100258886 0.226 NM_206808
CLYBL
citrate lyase beta like
chr1_+_117544371 0.225 NM_004258
CD101
CD101 molecule
chr19_+_2328679 0.225 SPPL2B
signal peptide peptidase-like 2B

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.