Motif ID: PDX1.p2

Z-value: 0.152


Transcription factors associated with PDX1.p2:

Gene SymbolEntrez IDGene Name
PDX1 3651 pancreatic and duodenal homeobox 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PDX1hg19_v1_chr13_+_28494136_284942720.364.8e-01Click!


Activity profile for motif PDX1.p2.

activity profile for motif PDX1.p2


Sorted Z-values histogram for motif PDX1.p2

Sorted Z-values for motif PDX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PDX1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_56143099 0.057 NM_001005204
NM_001013356
OR8U1
OR8U8
olfactory receptor, family 8, subfamily U, member 1
olfactory receptor, family 8, subfamily U, member 8
chr2_-_158300517 0.053 NM_004288
CYTIP
cytohesin 1 interacting protein
chr6_-_43423785 0.039 NM_206539
DLK2
delta-like 2 homolog (Drosophila)
chr16_-_67517715 0.034 NM_001138
AGRP
agouti related protein homolog (mouse)
chr2_-_166060552 0.027 NM_001081676
NM_001081677
NM_006922
SCN3A


sodium channel, voltage-gated, type III, alpha subunit


chr3_-_137832321 0.024 NM_001170538
DZIP1L
DAZ interacting protein 1-like
chr5_+_147648374 0.023 NM_001040129
SPINK13
serine peptidase inhibitor, Kazal type 13 (putative)
chr1_+_63063186 0.019 NM_014495
ANGPTL3
angiopoietin-like 3
chr7_+_93535819 0.017 NM_021955
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr17_+_47923271 0.017 NM_001242791
FLJ45513
uncharacterized LOC729220
chr6_-_133035180 0.015 NM_004666
VNN1
vanin 1
chr3_+_100238063 0.013 TMEM45A
transmembrane protein 45A
chr9_+_136501484 0.013 NM_000787
DBH
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr14_-_81864726 0.012 NM_033104
STON2
stonin 2
chr12_+_47610244 0.011 FAM113B
family with sequence similarity 113, member B
chr15_+_67841341 0.011 NM_001206804
MAP2K5
mitogen-activated protein kinase kinase 5
chr4_-_46996423 0.010 NM_000809
GABRA4
gamma-aminobutyric acid (GABA) A receptor, alpha 4
chr4_-_10023094 0.010 NM_020041
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr17_+_7482961 0.009 CD68
CD68 molecule
chr12_-_54019633 0.009 NM_001206683
ATF7
activating transcription factor 7
chr1_+_101003692 0.008 NM_022049
GPR88
G protein-coupled receptor 88
chr12_-_14849427 0.008 NM_004963
GUCY2C
guanylate cyclase 2C (heat stable enterotoxin receptor)
chr10_+_115310589 0.007 NM_001177660
HABP2
hyaluronan binding protein 2
chr9_+_97766414 0.007 C9orf3
chromosome 9 open reading frame 3
chr10_+_63808968 0.007 NM_001244638
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr1_+_40862471 0.007 NM_001198980
SMAP2
small ArfGAP2
chr2_+_185463292 0.007 ZNF804A
zinc finger protein 804A
chr17_+_7960201 0.006


chr17_+_7482980 0.006 CD68
CD68 molecule
chr12_-_121454285 0.006 NM_022895
C12orf43
chromosome 12 open reading frame 43
chr3_+_174577069 0.006 NM_207015
NAALADL2
N-acetylated alpha-linked acidic dipeptidase-like 2
chr18_-_51690988 0.006 MBD2
methyl-CpG binding domain protein 2
chr12_+_31800093 0.006 NM_001135864
METTL20
methyltransferase like 20
chr8_-_145060594 0.006 NM_032789
PARP10
poly (ADP-ribose) polymerase family, member 10
chr7_+_80275967 0.006 CD36
CD36 molecule (thrombospondin receptor)
chr8_-_17579729 0.006 NM_001001931
MTUS1
microtubule associated tumor suppressor 1
chrX_+_118708540 0.006 UBE2A
ubiquitin-conjugating enzyme E2A
chr9_+_33026482 0.005 DNAJA1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr14_-_47812394 0.005 NM_182830
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr16_+_57728711 0.005 NM_032269
CCDC135
coiled-coil domain containing 135
chr11_+_22696381 0.005 GAS2
growth arrest-specific 2
chr18_+_616671 0.005 NM_199167
CLUL1
clusterin-like 1 (retinal)
chrX_+_48687282 0.005 NM_181532
ERAS
ES cell expressed Ras
chr5_-_172083569 0.005


chr6_+_130339715 0.005 NM_001007102
NM_032438
L3MBTL3

l(3)mbt-like 3 (Drosophila)

chr11_+_123986103 0.005 NM_001130142
NM_014622
NM_198315
VWA5A


von Willebrand factor A domain containing 5A


chr1_+_10057254 0.005 NM_052960
RBP7
retinol binding protein 7, cellular
chr17_+_68071386 0.005 NM_018658
NM_170741
KCNJ16

potassium inwardly-rectifying channel, subfamily J, member 16

chr18_+_55888799 0.004 NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr6_+_147524866 0.004 STXBP5
syntaxin binding protein 5 (tomosyn)
chr12_-_54020081 0.004 NM_001130060
NM_001206682
NM_006856
ATF7


activating transcription factor 7


chr2_+_185463235 0.004 ZNF804A
zinc finger protein 804A
chrX_-_62780748 0.004 LOC92249
uncharacterized LOC92249
chrX_-_131547536 0.004 NM_001170701
NM_001170702
NM_001170703
MBNL3


muscleblind-like 3 (Drosophila)


chrX_+_99899388 0.004 SRPX2
sushi-repeat containing protein, X-linked 2
chr17_+_7482938 0.004 CD68
CD68 molecule
chr12_+_4699243 0.004 NM_003845
DYRK4
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 4
chr8_-_17580024 0.004 NM_001166393
MTUS1
microtubule associated tumor suppressor 1
chr12_+_4829751 0.004 NM_017417
GALNT8
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 8 (GalNAc-T8)
chr6_+_25754926 0.004 NM_005495
SLC17A4
solute carrier family 17 (sodium phosphate), member 4
chr15_+_40509628 0.004 NM_001128628
NM_001128629
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr4_+_88896801 0.004 NM_000582
NM_001040058
NM_001040060
NM_001251829
NM_001251830
SPP1




secreted phosphoprotein 1




chr6_-_134498973 0.004 NM_001143677
SGK1
serum/glucocorticoid regulated kinase 1
chr11_-_116663106 0.003 NM_001166598
NM_052968
APOA5

apolipoprotein A-V

chr18_+_28898051 0.003 NM_001942
DSG1
desmoglein 1
chr19_+_48828627 0.003 NM_001425
EMP3
epithelial membrane protein 3
chr10_+_116697914 0.003 NM_139169
TRUB1
TruB pseudouridine (psi) synthase homolog 1 (E. coli)
chr6_+_35310399 0.003 PPARD
peroxisome proliferator-activated receptor delta
chr16_+_70557726 0.003 SF3B3
splicing factor 3b, subunit 3, 130kDa
chr10_+_32856650 0.003 NM_024688
C10orf68
chromosome 10 open reading frame 68
chr18_+_55888750 0.003 NM_001144966
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like
chr16_+_70557688 0.003 NM_012426
SF3B3
splicing factor 3b, subunit 3, 130kDa
chr4_+_95376396 0.003 PDLIM5
PDZ and LIM domain 5
chr3_-_114343791 0.003 NM_001164346
ZBTB20
zinc finger and BTB domain containing 20
chr6_-_138539626 0.003 NM_021635
PBOV1
prostate and breast cancer overexpressed 1
chr12_+_75784849 0.002 GLIPR1L2
GLI pathogenesis-related 1 like 2
chr1_+_36636690 0.002 MAP7D1
MAP7 domain containing 1
chr3_+_45017749 0.002 EXOSC7
exosome component 7
chr1_-_186417855 0.002 NM_022576
PDC
phosducin
chr3_-_114478117 0.002 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr2_+_24807345 0.002 NM_003743
NM_147223
NM_147233
NCOA1


nuclear receptor coactivator 1


chr8_-_17555158 0.002 NM_020749
MTUS1
microtubule associated tumor suppressor 1
chr1_-_155649243 0.002


chrX_+_99899162 0.002 NM_014467
SRPX2
sushi-repeat containing protein, X-linked 2
chr17_+_76000248 0.002 NM_001142640
NM_018996
TNRC6C

trinucleotide repeat containing 6C

chr17_+_18625335 0.002 NM_001037330
TRIM16L
tripartite motif containing 16-like
chr6_+_167704802 0.002 NM_001143947
NM_018974
UNC93A

unc-93 homolog A (C. elegans)

chr16_+_8814567 0.002 NM_001127448
ABAT
4-aminobutyrate aminotransferase
chr11_+_22696318 0.002 NM_005256
GAS2
growth arrest-specific 2
chr7_-_27166638 0.002 NM_153631
HOXA3
homeobox A3
chr3_+_45017729 0.002 NM_015004
EXOSC7
exosome component 7
chr7_-_44580857 0.002 NM_001101648
NM_013389
NPC1L1

NPC1 (Niemann-Pick disease, type C1, gene)-like 1

chr1_-_33841142 0.002 NM_198040
PHC2
polyhomeotic homolog 2 (Drosophila)
chr4_-_39523132 0.002 UGDH
UDP-glucose 6-dehydrogenase
chr6_+_167536240 0.002 NM_031409
CCR6
chemokine (C-C motif) receptor 6
chr3_+_148447966 0.002 NM_032049
AGTR1
angiotensin II receptor, type 1
chr10_+_86184685 0.002 FAM190B
family with sequence similarity 190, member B
chr3_-_45017600 0.002 NM_001135179
NM_016598
ZDHHC3

zinc finger, DHHC-type containing 3

chr17_-_1412995 0.002 INPP5K
inositol polyphosphate-5-phosphatase K
chr7_+_120965420 0.002 NM_016087
WNT16
wingless-type MMTV integration site family, member 16
chr12_+_75784878 0.001 NM_152436
GLIPR1L2
GLI pathogenesis-related 1 like 2
chr5_-_75919051 0.001 NM_004101
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr3_-_120400957 0.001 HGD
homogentisate 1,2-dioxygenase
chr7_+_156435670 0.001 NM_001184997
RNF32
ring finger protein 32
chr10_+_70980058 0.001 NM_025130
HKDC1
hexokinase domain containing 1
chr4_-_139163222 0.001 NM_014331
SLC7A11
solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
chr2_-_96947640 0.001 SNRNP200
small nuclear ribonucleoprotein 200kDa (U5)
chr12_-_121454210 0.001 C12orf43
chromosome 12 open reading frame 43
chr4_-_170077807 0.001 SH3RF1
SH3 domain containing ring finger 1
chrX_-_10645726 0.001 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr20_+_31037447 0.001


chr5_+_140718353 0.001 NM_018915
NM_032009
PCDHGA2

protocadherin gamma subfamily A, 2

chr16_+_70557724 0.001 SF3B3
splicing factor 3b, subunit 3, 130kDa
chr12_-_57873364 0.001 NM_001080157
ARHGAP9
Rho GTPase activating protein 9
chr2_-_216259197 0.001 FN1
fibronectin 1
chr11_-_66488712 0.001 NM_006946
SPTBN2
spectrin, beta, non-erythrocytic 2
chr1_-_21605984 0.001 NM_001113347
ECE1
endothelin converting enzyme 1
chr12_+_80838125 0.001 NM_001145026
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr6_+_158733691 0.001 NM_001007466
NM_020245
TULP4

tubby like protein 4

chr2_+_228192227 0.001 NM_020194
MFF
mitochondrial fission factor
chr3_+_49547867 0.001 DAG1
dystroglycan 1 (dystrophin-associated glycoprotein 1)
chr5_+_34684611 0.000 NM_001145521
NM_001145525
RAI14

retinoic acid induced 14

chr2_-_100046262 0.000 REV1
REV1 homolog (S. cerevisiae)
chr1_+_28764660 0.000 NM_023923
PHACTR4
phosphatase and actin regulator 4
chr16_-_71782165 0.000 AP1G1
adaptor-related protein complex 1, gamma 1 subunit
chr2_-_188419049 0.000 TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr4_-_24981769 0.000 NM_173463
CCDC149
coiled-coil domain containing 149
chr16_+_31724577 0.000 ZNF720
zinc finger protein 720
chr1_-_155649597 0.000 NM_001198899
YY1AP1
YY1 associated protein 1
chr5_+_140235594 0.000 NM_018901
NM_031859
NM_031860
PCDHA10


protocadherin alpha 10


chr5_-_142815076 0.000 NM_001018074
NM_001018075
NM_001018077
NR3C1


nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)


chr3_-_47933997 0.000 MAP4
microtubule-associated protein 4
chr6_+_42531736 0.000 NM_001184801
NM_015255
UBR2

ubiquitin protein ligase E3 component n-recognin 2

chr1_+_84609941 0.000 NM_182948
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr6_+_46761093 0.000 NM_005588
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr5_-_77844975 0.000 LHFPL2
lipoma HMGIC fusion partner-like 2
chr11_+_28131830 0.000 METTL15
methyltransferase like 15
chr3_+_151531860 0.000 NM_001086
AADAC
arylacetamide deacetylase (esterase)
chr1_-_16763887 0.000 NM_198546
SPATA21
spermatogenesis associated 21
chr6_-_131321868 0.000 NM_001252660
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr4_+_113970784 0.000 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal


Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.