Motif ID: POU3F1..4.p2

Z-value: 0.780


Transcription factors associated with POU3F1..4.p2:

Gene SymbolEntrez IDGene Name
POU3F1 5453 POU class 3 homeobox 1
POU3F2 5454 POU class 3 homeobox 2
POU3F3 5455 POU class 3 homeobox 3
POU3F4 5456 POU class 3 homeobox 4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
POU3F2hg19_v1_chr6_+_99282597_992827480.473.5e-01Click!


Activity profile for motif POU3F1..4.p2.

activity profile for motif POU3F1..4.p2


Sorted Z-values histogram for motif POU3F1..4.p2

Sorted Z-values for motif POU3F1..4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU3F1..4.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_371994 0.460 NM_001190997
NM_001243392
NM_016615
SLC6A13


solute carrier family 6 (neurotransmitter transporter, GABA), member 13


chr1_+_171283372 0.443 NM_002022
FMO4
flavin containing monooxygenase 4
chrX_+_65384078 0.432 NM_001130860
NM_014799
HEPH

hephaestin

chr2_-_197674875 0.375 NM_213608
C2orf66
chromosome 2 open reading frame 66
chr16_+_4845265 0.373 NM_001253793
NM_001253794
LOC440335

uncharacterized LOC440335

chr4_-_76957139 0.339 NM_005409
CXCL11
chemokine (C-X-C motif) ligand 11
chr8_-_6420454 0.321 NM_001118887
NM_001118888
NM_001147
ANGPT2


angiopoietin 2


chr12_-_10542616 0.287 NM_007360
KLRK1
killer cell lectin-like receptor subfamily K, member 1
chr1_+_186798031 0.284 NM_024420
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr4_+_87857394 0.260


chr12_+_80603232 0.231 NM_173591
OTOGL
otogelin-like
chrX_-_15620191 0.219 NM_021804
ACE2
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr5_+_86676620 0.206


chr17_-_76732944 0.203


chr16_+_15031299 0.186 NM_006985
NPIP
nuclear pore complex interacting protein
chr7_-_20256942 0.181 NM_182762
MACC1
metastasis associated in colon cancer 1
chrX_-_48327739 0.179 SLC38A5
solute carrier family 38, member 5
chr6_+_49467670 0.159 NM_001010904
GLYATL3
glycine-N-acyltransferase-like 3
chr9_-_111618209 0.150 NM_006686
ACTL7B
actin-like 7B
chr11_-_85469043 0.145 NM_001162951
NM_001162953
SYTL2

synaptotagmin-like 2

chr19_+_44455379 0.144 NM_013359
ZNF221
zinc finger protein 221
chr7_+_141463896 0.139 NM_016943
TAS2R3
taste receptor, type 2, member 3
chr9_+_99691285 0.138 NM_001045477
NM_001170741
FAM22G

family with sequence similarity 22, member G

chr11_+_105480799 0.137 NM_000829
NM_001077243
NM_001077244
GRIA4


glutamate receptor, ionotrophic, AMPA 4


chrX_+_100805415 0.137 NM_016608
ARMCX1
armadillo repeat containing, X-linked 1
chr10_-_52008312 0.134 NM_001143974
NM_019893
ASAH2

N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2

chr2_-_202222066 0.133 NM_001127391
NM_139163
ALS2CR12

amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 12

chr3_-_160101443 0.131 NM_001190242
IFT80
intraflagellar transport 80 homolog (Chlamydomonas)
chr6_-_152702329 0.130 SYNE1
spectrin repeat containing, nuclear envelope 1
chr11_+_5775922 0.128 NM_001005175
OR52N4
olfactory receptor, family 52, subfamily N, member 4
chr22_+_21821458 0.125 NM_001207052
TMEM191C
transmembrane protein 191C
chr7_-_83278478 0.120 NM_012431
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr7_-_132333446 0.120 NM_181775
PLXNA4
plexin A4
chr4_-_38858407 0.117 NM_006068
TLR6
toll-like receptor 6
chr3_-_126327397 0.113 NM_001039783
TXNRD3NB
thioredoxin reductase 3 neighbor
chr13_-_61989209 0.112 PCDH20
protocadherin 20
chr13_-_78492906 0.112 NM_001122659
NM_003991
EDNRB

endothelin receptor type B

chr10_+_114043413 0.112 NM_058222
TECTB
tectorin beta
chr4_-_109087876 0.111 NM_001166119
LEF1
lymphoid enhancer-binding factor 1
chr11_-_67205151 0.109 NM_005608
PTPRCAP
protein tyrosine phosphatase, receptor type, C-associated protein
chr2_-_200213802 0.107 SATB2
SATB homeobox 2
chr4_+_88896868 0.104 SPP1
secreted phosphoprotein 1
chr2_-_198540583 0.103 NM_144629
RFTN2
raftlin family member 2
chr6_+_27107060 0.103 NM_003495
HIST2H4B
HIST1H4I
histone cluster 2, H4b
histone cluster 1, H4i
chr4_+_88896838 0.102 SPP1
secreted phosphoprotein 1
chr6_-_139613114 0.102 NM_153235
TXLNB
taxilin beta
chr14_-_81408030 0.101 CEP128
centrosomal protein 128kDa
chr1_+_109255555 0.097 NM_001144937
FNDC7
fibronectin type III domain containing 7
chr22_-_38881529 0.094 DDX17
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr6_-_31689455 0.092 NM_025261
LY6G6C
lymphocyte antigen 6 complex, locus G6C
chr5_+_140213968 0.091 NM_018910
NM_031852
PCDHA7

protocadherin alpha 7

chr17_+_42925278 0.089 NM_016438
HIGD1B
HIG1 hypoxia inducible domain family, member 1B
chr13_-_60325073 0.086


chr1_+_230883129 0.085 NM_006615
NM_016452
CAPN9

calpain 9

chr19_-_56704420 0.085 NM_001080456
ZSCAN5B
zinc finger and SCAN domain containing 5B
chr7_-_83270746 0.084 NM_001178129
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr5_-_157002739 0.084 NM_033274
ADAM19
ADAM metallopeptidase domain 19
chr15_+_78384926 0.084 NM_001101404
SH2D7
SH2 domain containing 7
chr12_+_52281743 0.081 NM_001130015
NM_182608
ANKRD33

ankyrin repeat domain 33

chr1_+_197237333 0.081 NM_001193640
NM_201253
CRB1

crumbs homolog 1 (Drosophila)

chr12_+_62954275 0.079 MON2
MON2 homolog (S. cerevisiae)
chr4_-_100212085 0.077 NM_000667
ADH1A
alcohol dehydrogenase 1A (class I), alpha polypeptide
chr6_-_46889620 0.077 NM_001098518
GPR116
G protein-coupled receptor 116
chr5_+_147582338 0.076 NM_001195290
NM_205841
SPINK6

serine peptidase inhibitor, Kazal type 6

chr2_+_143635194 0.075 NM_001032998
NM_001199241
NM_003937
KYNU


kynureninase


chr7_+_102023016 0.074


chr11_+_5710926 0.074 TRIM22
tripartite motif containing 22
chr1_-_89641722 0.073 NM_207398
GBP7
guanylate binding protein 7
chr3_+_25469833 0.071 NM_000965
RARB
retinoic acid receptor, beta
chr1_+_104097321 0.071 NM_020978
AMY2B
amylase, alpha 2B (pancreatic)
chr17_+_28268622 0.071 NM_198529
EFCAB5
EF-hand calcium binding domain 5
chr2_+_234580504 0.070 NM_021027
UGT1A9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr2_-_77749335 0.068 NM_001134745
NM_024993
LRRTM4

leucine rich repeat transmembrane neuronal 4

chr7_+_28338939 0.068 NM_182899
CREB5
cAMP responsive element binding protein 5
chr2_+_143635225 0.066 KYNU
kynureninase
chr19_-_10679328 0.065 CDKN2D
cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)
chr2_+_234601511 0.065 NM_001072
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr4_+_187148624 0.065 NM_000892
KLKB1
kallikrein B, plasma (Fletcher factor) 1
chr5_-_157002705 0.065


chr14_-_75330535 0.065 NM_001080408
NM_001243007
PROX2

prospero homeobox 2

chr2_-_111230651 0.063 NM_001205288
NM_033514
LIMS3-LOC440895
LIMS3L
LIMS3
LIMS3-LOC440895 readthrough
LIM and senescent cell antigen-like domains 3-like
LIM and senescent cell antigen-like domains 3
chrX_-_124097601 0.062 NM_001163278
NM_001163279
NM_014253
ODZ1


odz, odd Oz/ten-m homolog 1 (Drosophila)


chr11_+_94800055 0.062 NM_032102
SRSF8
serine/arginine-rich splicing factor 8
chr9_-_70490164 0.060 NM_001024916
NM_201453
CBWD5
CBWD3
COBW domain containing 5
COBW domain containing 3
chr8_-_124749573 0.060 NM_001003954
NM_004306
ANXA13

annexin A13

chr13_+_113633625 0.059 MCF2L
MCF.2 cell line derived transforming sequence-like
chr4_+_88896801 0.059 NM_000582
NM_001040058
NM_001040060
NM_001251829
NM_001251830
SPP1




secreted phosphoprotein 1




chr3_+_188889762 0.059 NM_198485
TPRG1
tumor protein p63 regulated 1
chr3_-_124653571 0.058 NM_033049
MUC13
mucin 13, cell surface associated
chr2_+_135596185 0.058 NM_138326
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr10_+_32856650 0.058 NM_024688
C10orf68
chromosome 10 open reading frame 68
chr4_-_100242487 0.058 NM_000668
ADH1A
ADH1B
alcohol dehydrogenase 1A (class I), alpha polypeptide
alcohol dehydrogenase 1B (class I), beta polypeptide
chr11_-_30601919 0.057 NM_001584
MPPED2
metallophosphoesterase domain containing 2
chr5_-_41213513 0.057 NM_000065
C6
complement component 6
chr3_-_168865521 0.057 NM_001164000
MECOM
MDS1 and EVI1 complex locus
chr6_+_17282931 0.056 NM_153020
RBM24
RNA binding motif protein 24
chr1_+_157963062 0.056 NM_018240
KIRREL
kin of IRRE like (Drosophila)
chr13_-_60587298 0.055 NM_030932
DIAPH3
diaphanous homolog 3 (Drosophila)
chr18_+_67068134 0.054 NM_152721
DOK6
docking protein 6
chr13_+_99058147 0.053


chr9_+_35042222 0.053 NM_001040410
NM_203299
C9orf131

chromosome 9 open reading frame 131

chr18_-_48346297 0.052 NM_001127175
NM_001127176
NM_031939
MRO


maestro


chr13_+_97874704 0.051 MBNL2
muscleblind-like 2 (Drosophila)
chr13_-_78493902 0.050 NM_001201397
EDNRB
endothelin receptor type B
chr6_+_26104103 0.050 NM_003542
HIST2H4B
HIST1H4C
histone cluster 2, H4b
histone cluster 1, H4c
chr1_-_21377387 0.050 EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chrX_-_73834427 0.049


chr5_-_146460991 0.049 NM_181677
NM_181678
PPP2R2B

protein phosphatase 2, regulatory subunit B, beta

chr1_-_162346579 0.048 NM_182581
C1orf111
chromosome 1 open reading frame 111
chr11_+_56143099 0.048 NM_001005204
NM_001013356
OR8U1
OR8U8
olfactory receptor, family 8, subfamily U, member 1
olfactory receptor, family 8, subfamily U, member 8
chr15_-_56209305 0.046 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr1_+_66798095 0.046 PDE4B
phosphodiesterase 4B, cAMP-specific
chr5_+_149340287 0.046 NM_000112
SLC26A2
solute carrier family 26 (sulfate transporter), member 2
chr15_-_50838901 0.045 NM_203494
USP50
ubiquitin specific peptidase 50
chr12_-_16759939 0.044 NM_001243613
LMO3
LIM domain only 3 (rhombotin-like 2)
chr12_-_57472573 0.044 NM_001130963
NM_015257
TMEM194A

transmembrane protein 194A

chr1_+_68297985 0.043 LOC100289178
uncharacterized LOC100289178
chr14_+_51026742 0.043 NM_015915
NM_181598
ATL1

atlastin GTPase 1

chr11_-_5863126 0.043 NM_001005167
OR52E6
olfactory receptor, family 52, subfamily E, member 6
chr6_-_136788012 0.042 NM_001198615
MAP7
microtubule-associated protein 7
chr21_-_36421195 0.041 RUNX1
runt-related transcription factor 1
chr20_+_42984088 0.041 HNF4A
hepatocyte nuclear factor 4, alpha
chr6_-_117150197 0.041 NM_148963
GPRC6A
G protein-coupled receptor, family C, group 6, member A
chr7_+_139528951 0.041 NM_001061
NM_001166253
NM_030984
TBXAS1


thromboxane A synthase 1 (platelet)


chr15_+_71184781 0.041 NM_001199017
NM_017691
NM_001199018
LRRC49


leucine rich repeat containing 49


chr3_+_111758464 0.040 NM_001042575
TMPRSS7
transmembrane protease, serine 7
chrX_-_73834460 0.039 NM_016120
NM_183353
RLIM

ring finger protein, LIM domain interacting

chr13_+_97874540 0.039 NM_144778
NM_207304
MBNL2

muscleblind-like 2 (Drosophila)

chr1_-_169396654 0.039 NM_021179
C1orf114
chromosome 1 open reading frame 114
chr1_+_178310605 0.038 NM_004841
RASAL2
RAS protein activator like 2
chr17_-_67057046 0.038 NM_080283
ABCA9
ATP-binding cassette, sub-family A (ABC1), member 9
chr8_-_17579729 0.037 NM_001001931
MTUS1
microtubule associated tumor suppressor 1
chr4_-_100485173 0.037 NM_001134665
NM_001134666
RG9MTD2

RNA (guanine-9-) methyltransferase domain containing 2

chr6_+_159070994 0.037 NM_001009991
NM_001242384
NM_001242394
NM_001242395
SYTL3



synaptotagmin-like 3



chr4_-_70518964 0.037 NM_001252274
NM_001252275
NM_006798
UGT2A1


UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus


chr12_-_16759733 0.037 NM_001243610
LMO3
LIM domain only 3 (rhombotin-like 2)
chr12_-_18243052 0.036 NM_024730
RERGL
RERG/RAS-like
chr5_+_71502700 0.036 MAP1B
microtubule-associated protein 1B
chrX_+_99899162 0.036 NM_014467
SRPX2
sushi-repeat containing protein, X-linked 2
chr8_+_28748030 0.036 NM_024567
HMBOX1
homeobox containing 1
chr15_+_40509628 0.036 NM_001128628
NM_001128629
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr3_+_28431986 0.035 NM_001040432
ZCWPW2
zinc finger, CW type with PWWP domain 2
chr11_-_73720281 0.035 NM_003356
NM_022803
UCP3

uncoupling protein 3 (mitochondrial, proton carrier)

chr2_+_210444364 0.035 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr1_+_182419255 0.035 NM_001137669
RGSL1
regulator of G-protein signaling like 1
chr6_-_138820580 0.035


chr2_-_180610768 0.035 NM_001113397
ZNF385B
zinc finger protein 385B
chr11_-_34535302 0.035 NM_001243080
NM_001422
ELF5

E74-like factor 5 (ets domain transcription factor)

chr18_+_616671 0.035 NM_199167
CLUL1
clusterin-like 1 (retinal)
chr5_-_75919051 0.034 NM_004101
F2RL2
coagulation factor II (thrombin) receptor-like 2
chrX_-_73834430 0.034 RLIM
ring finger protein, LIM domain interacting
chr1_-_54483802 0.034 NM_001010978
LDLRAD1
low density lipoprotein receptor class A domain containing 1
chr1_-_110933635 0.034 SLC16A4
solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
chr1_-_89591685 0.033 NM_004120
GBP2
guanylate binding protein 2, interferon-inducible
chr1_+_174128654 0.033 RABGAP1L
RAB GTPase activating protein 1-like
chr3_+_69985750 0.033 NM_000248
NM_001184968
NM_198158
NM_198178
MITF



microphthalmia-associated transcription factor



chr11_+_111789600 0.033 NM_080659
C11orf52
chromosome 11 open reading frame 52
chr1_-_21377452 0.033 EIF4G3
eukaryotic translation initiation factor 4 gamma, 3
chr7_-_124405680 0.033 NM_005302
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chr1_+_171217632 0.032 NM_002021
FMO1
flavin containing monooxygenase 1
chr19_+_46001730 0.032 NM_001080401
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr9_+_79968344 0.032 VPS13A
vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr3_-_114102488 0.032 NM_001164342
ZBTB20
zinc finger and BTB domain containing 20
chr6_+_147829784 0.031 NM_001030060
SAMD5
sterile alpha motif domain containing 5
chr17_-_59668540 0.031 NM_199290
NACA2
nascent polypeptide-associated complex alpha subunit 2
chr14_+_78870092 0.031 NM_004796
NRXN3
neurexin 3
chr2_+_183580960 0.031 NM_018981
DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr11_-_85780899 0.030 NM_001206947
PICALM
phosphatidylinositol binding clathrin assembly protein
chr2_+_228678556 0.030 NM_001130046
NM_004591
CCL20

chemokine (C-C motif) ligand 20

chr3_-_123339423 0.030 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr3_-_185270258 0.029 NM_139248
LIPH
lipase, member H
chr21_+_43619798 0.029 NM_207627
NM_207628
ABCG1

ATP-binding cassette, sub-family G (WHITE), member 1

chr8_-_124544376 0.029 NM_148177
FBXO32
F-box protein 32
chr7_+_128580725 0.029 NM_001098627
IRF5
interferon regulatory factor 5
chrX_+_129139163 0.028 NM_021946
BCORL1
BCL6 corepressor-like 1
chr19_-_10679620 0.028 NM_001800
NM_079421
CDKN2D

cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4)

chr20_+_816710 0.028 NM_207121
FAM110A
family with sequence similarity 110, member A
chrX_-_105282714 0.028 NM_000354
SERPINA7
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr11_-_63330854 0.028 NM_017878
HRASLS2
HRAS-like suppressor 2
chr7_+_28475233 0.027 NM_004904
CREB5
cAMP responsive element binding protein 5
chr13_-_26789062 0.027 RNF6
ring finger protein (C3H2C3 type) 6
chr19_-_54804172 0.026 NM_001172654
NM_006865
LILRA3

LILRA6
leukocyte immunoglobulin-like receptor, subfamily A (without TM domain), member 3

leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
chr1_+_114472438 0.026 HIPK1
homeodomain interacting protein kinase 1
chr19_-_37663567 0.026 NM_152655
ZNF585A
zinc finger protein 585A
chr9_-_32526164 0.026 NM_014314
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr21_-_33957746 0.026 NM_144659
TCP10L
t-complex 10 (mouse)-like
chr14_+_96846021 0.026 NM_016472
C14orf129
chromosome 14 open reading frame 129
chr1_-_173020011 0.025 NM_005092
TNFSF18
tumor necrosis factor (ligand) superfamily, member 18
chr2_+_166095911 0.025 NM_001040142
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr6_-_64029847 0.025 NM_001143940
NM_016571
LGSN

lengsin, lens protein with glutamine synthetase domain

chr16_+_81812899 0.025 PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr13_-_22178282 0.025 EFHA1
EF-hand domain family, member A1
chr10_+_29698462 0.024 LOC387647
patched domain containing 3 pseudogene
chr12_+_57849086 0.024 NM_031479
INHBE
inhibin, beta E
chr3_+_155838336 0.024 NM_172160
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr2_-_201936350 0.024 FAM126B
family with sequence similarity 126, member B
chr4_+_123844210 0.024 NM_145207
SPATA5
spermatogenesis associated 5
chr10_+_105127709 0.024 NM_006951
TAF5
TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
chr7_-_11871735 0.024 NM_015204
THSD7A
thrombospondin, type I, domain containing 7A
chr18_+_19353635 0.024 MIB1
mindbomb homolog 1 (Drosophila)

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.