Motif ID: POU6F1.p2

Z-value: 0.818


Transcription factors associated with POU6F1.p2:

Gene SymbolEntrez IDGene Name
POU6F1 5463 POU class 6 homeobox 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
POU6F1hg19_v1_chr12_-_51611476_516115900.197.1e-01Click!


Activity profile for motif POU6F1.p2.

activity profile for motif POU6F1.p2


Sorted Z-values histogram for motif POU6F1.p2

Sorted Z-values for motif POU6F1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of POU6F1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrM_+_10123 1.245


chr6_-_26108320 0.440 NM_005323
HIST1H1T
histone cluster 1, H1t
chr2_+_210444154 0.385 MAP2
microtubule-associated protein 2
chr19_-_33360641 0.384 NM_001126335
NM_001243036
NM_014270
SLC7A9


solute carrier family 7 (glycoprotein-associated amino acid transporter light chain, bo,+ system), member 9


chr7_+_93535819 0.308 NM_021955
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr9_+_108424737 0.267 NM_005421
TAL2
T-cell acute lymphocytic leukemia 2
chr3_-_151987332 0.255 LOC401093
uncharacterized LOC401093
chr5_-_137475076 0.244 NM_003551
NME5
non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)
chr2_+_210444364 0.238 NM_002374
NM_031845
NM_031847
MAP2


microtubule-associated protein 2


chr5_-_75919051 0.235 NM_004101
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr17_-_40833840 0.234 NM_016602
CCR10
chemokine (C-C motif) receptor 10
chr13_+_24144402 0.220 NM_001204459
NM_148957
TNFRSF19

tumor necrosis factor receptor superfamily, member 19

chr14_-_57960432 0.213 NM_018168
C14orf105
chromosome 14 open reading frame 105
chr3_+_151591428 0.213 NM_033050
SUCNR1
succinate receptor 1
chr9_-_215892 0.210 NM_152569
C9orf66
chromosome 9 open reading frame 66
chr9_-_95166827 0.199 NM_014057
NM_033014
OGN

osteoglycin

chr14_+_51026742 0.194 NM_015915
NM_181598
ATL1

atlastin GTPase 1

chr15_+_54305100 0.180 NM_001080534
UNC13C
unc-13 homolog C (C. elegans)
chr10_+_96443250 0.176 NM_000772
NM_001128925
CYP2C18

cytochrome P450, family 2, subfamily C, polypeptide 18

chr1_+_168250277 0.172 NM_005149
TBX19
T-box 19
chr7_-_107880492 0.164 NM_001037132
NRCAM
neuronal cell adhesion molecule
chr17_-_38978824 0.157 NM_000421
KRT10
keratin 10
chr1_-_197036350 0.145 NM_001994
F13B
coagulation factor XIII, B polypeptide
chr11_+_58710721 0.135 NM_001220496
NM_080661
GLYATL1

glycine-N-acyltransferase-like 1

chr5_-_156390206 0.135 NM_001146726
NM_138379
TIMD4

T-cell immunoglobulin and mucin domain containing 4

chr10_-_5045967 0.128 NM_001135241
AKR1C2
aldo-keto reductase family 1, member C2 (dihydrodiol dehydrogenase 2; bile acid binding protein; 3-alpha hydroxysteroid dehydrogenase, type III)
chrX_-_139866582 0.122 NM_004065
CDR1
cerebellar degeneration-related protein 1, 34kDa
chr6_-_47254143 0.114 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr2_-_72371188 0.113 CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr12_-_51611476 0.113 POU6F1
POU class 6 homeobox 1
chr1_+_180199432 0.110 NM_033343
LHX4
LIM homeobox 4
chr11_-_83393436 0.107 NM_001142702
DLG2
discs, large homolog 2 (Drosophila)
chr7_+_119913688 0.106 NM_012281
KCND2
potassium voltage-gated channel, Shal-related subfamily, member 2
chr3_-_149086884 0.104 TM4SF1
transmembrane 4 L six family member 1
chr5_-_27038650 0.103 NM_016279
CDH9
cadherin 9, type 2 (T1-cadherin)
chr11_+_19372270 0.097 NM_001111018
NAV2
neuron navigator 2
chr17_+_42925278 0.096 NM_016438
HIGD1B
HIG1 hypoxia inducible domain family, member 1B
chr13_+_113698907 0.096 MCF2L
MCF.2 cell line derived transforming sequence-like
chr17_+_57915192 0.096


chr7_-_92855780 0.094 NM_001039372
HEPACAM2
HEPACAM family member 2
chrM_+_9182 0.094


chr1_+_26503973 0.093 NM_006314
CNKSR1
connector enhancer of kinase suppressor of Ras 1
chrX_-_106146546 0.092 NM_001171706
NM_138382
RIPPLY1

ripply1 homolog (zebrafish)

chr1_+_101003692 0.091 NM_022049
GPR88
G protein-coupled receptor 88
chr2_-_228244005 0.091 NM_024795
TM4SF20
transmembrane 4 L six family member 20
chrX_+_47053192 0.091 NM_003334
UBA1
ubiquitin-like modifier activating enzyme 1
chr2_+_24807345 0.089 NM_003743
NM_147223
NM_147233
NCOA1


nuclear receptor coactivator 1


chr15_-_50838901 0.088 NM_203494
USP50
ubiquitin specific peptidase 50
chrX_+_47053271 0.088 UBA1
ubiquitin-like modifier activating enzyme 1
chr2_+_190540710 0.087 NM_144708
ANKAR
ankyrin and armadillo repeat containing
chr3_-_13057130 0.087


chr3_-_57234279 0.084 NM_003865
HESX1
HESX homeobox 1
chr10_+_77542518 0.080 NM_032024
C10orf11
chromosome 10 open reading frame 11
chr3_+_158787040 0.078 NM_001197113
NM_001197114
NM_001042705
NM_001042706
NM_001197100
IQCJ-SCHIP1

IQCJ


IQCJ-SCHIP1 readthrough

IQ motif containing J


chr11_+_124439892 0.077 NM_001005194
OR8A1
olfactory receptor, family 8, subfamily A, member 1
chr9_-_134955243 0.076 NM_004269
CRSP8P
MED27
mediator complex subunit 27 pseudogene
mediator complex subunit 27
chr22_-_36236264 0.073 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chrX_+_47053213 0.073 UBA1
ubiquitin-like modifier activating enzyme 1
chr16_-_70835044 0.073 VAC14
Vac14 homolog (S. cerevisiae)
chr7_+_100026412 0.072 NM_001194990
NM_001194991
NM_001194992
MEPCE


methylphosphate capping enzyme


chr6_+_31496738 0.072 NM_001011700
MCCD1
mitochondrial coiled-coil domain 1
chr6_+_54173202 0.072 NM_014464
TINAG
tubulointerstitial nephritis antigen
chr18_+_28956739 0.071 NM_001134453
NM_177986
DSG4

desmoglein 4

chr3_-_169487602 0.071 NM_032487
ARPM1
actin related protein M1
chr4_+_41614911 0.071 NM_001112719
NM_001112720
LIMCH1

LIM and calponin homology domains 1

chr2_-_216245573 0.070 FN1
fibronectin 1
chr1_+_160336856 0.070 NM_005598
NHLH1
nescient helix loop helix 1
chr1_+_67773046 0.069 NM_001559
IL12RB2
interleukin 12 receptor, beta 2
chr1_+_109255555 0.064 NM_001144937
FNDC7
fibronectin type III domain containing 7
chr6_-_47277646 0.063 NM_014452
TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chrM_-_9203 0.063


chr7_+_107110501 0.063 NM_005295
GPR22
G protein-coupled receptor 22
chrX_-_119379060 0.062 NKAPP1
NFKB activating protein pseudogene 1
chr11_+_77774902 0.062 NM_003251
THRSP
thyroid hormone responsive
chrX_+_47053234 0.062 UBA1
ubiquitin-like modifier activating enzyme 1
chrX_+_41548225 0.061 NM_001097579
NM_005300
GPR34

G protein-coupled receptor 34

chr3_+_128199744 0.061


chr1_+_46379258 0.061 MAST2
microtubule associated serine/threonine kinase 2
chr7_-_108142934 0.061 PNPLA8
patatin-like phospholipase domain containing 8
chr6_-_47253962 0.061 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chrX_+_28605558 0.060 NM_014271
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr14_+_51026853 0.060 ATL1
atlastin GTPase 1
chr16_-_70835061 0.057 VAC14
Vac14 homolog (S. cerevisiae)
chr16_-_70834884 0.057 VAC14
Vac14 homolog (S. cerevisiae)
chr22_-_36236330 0.057 RBFOX2
RNA binding protein, fox-1 homolog (C. elegans) 2
chr7_+_100027253 0.056 NM_019606
MEPCE
methylphosphate capping enzyme
chr1_+_84647342 0.055 NM_001242862
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chrX_+_47053227 0.054 UBA1
ubiquitin-like modifier activating enzyme 1
chr7_+_100026413 0.054 MEPCE
methylphosphate capping enzyme
chr11_-_16497917 0.052 NM_033326
SOX6
SRY (sex determining region Y)-box 6
chr2_+_128403438 0.052 NM_001161415
NM_001161416
NM_001161417
NM_005291
GPR17



G protein-coupled receptor 17



chr10_+_99498233 0.052 NM_001002261
ZFYVE27
zinc finger, FYVE domain containing 27
chr18_+_47088400 0.052 NM_006033
LIPG
lipase, endothelial
chrX_-_33229428 0.050 NM_004006
DMD
dystrophin
chr4_+_151503076 0.049 NM_006439
MAB21L2
mab-21-like 2 (C. elegans)
chr21_-_31852631 0.049 NM_181607
KRTAP19-1
keratin associated protein 19-1
chr16_-_70835060 0.048 NM_018052
VAC14
Vac14 homolog (S. cerevisiae)
chr8_+_87111132 0.048 NM_152565
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr13_+_97928414 0.048 MBNL2
muscleblind-like 2 (Drosophila)
chr7_-_100026284 0.047 NM_017984
ZCWPW1
zinc finger, CW type with PWWP domain 1
chr4_+_160188997 0.047 NM_014247
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr7_-_27159213 0.047 NM_030661
HOXA3
homeobox A3
chr16_-_70835067 0.047 VAC14
Vac14 homolog (S. cerevisiae)
chr6_+_53883713 0.047 NM_138569
MLIP
muscular LMNA-interacting protein
chr9_-_134955056 0.047 MED27
mediator complex subunit 27
chr12_-_70093064 0.046 NM_032735
BEST3
bestrophin 3
chr17_-_56492938 0.046 RNF43
ring finger protein 43
chrM_+_10361 0.045


chr5_-_160279045 0.045 NM_025153
ATP10B
ATPase, class V, type 10B
chr9_-_88874518 0.045 NM_001010907
C9orf153
chromosome 9 open reading frame 153
chr18_+_616671 0.044 NM_199167
CLUL1
clusterin-like 1 (retinal)
chrX_+_47053302 0.043 UBA1
ubiquitin-like modifier activating enzyme 1
chr1_+_151032683 0.043 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr16_+_4902076 0.042 NM_016936
UBN1
ubinuclein 1
chr4_-_25032306 0.042 NM_018176
LGI2
leucine-rich repeat LGI family, member 2
chr7_+_55433140 0.041 NM_018697
LANCL2
LanC lantibiotic synthetase component C-like 2 (bacterial)
chr1_+_78470593 0.041 NM_007034
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr7_+_72396799 0.040 POM121
POM121 membrane glycoprotein
chr10_+_101542460 0.040 NM_000392
ABCC2
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr18_-_47814691 0.040 NM_001101654
NM_014593
CXXC1

CXXC finger protein 1

chr17_-_9479139 0.039 NM_004853
STX8
syntaxin 8
chr19_-_48759141 0.039 NM_001184902
NM_001184904
CARD8

caspase recruitment domain family, member 8

chr10_+_5005601 0.039 AKR1C1
AKR1C3
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr7_+_28338939 0.038 NM_182899
CREB5
cAMP responsive element binding protein 5
chrM_+_9217 0.038


chr7_-_41742666 0.038 NM_002192
INHBA
inhibin, beta A
chr11_-_124267246 0.038 NM_001005467
OR8B3
olfactory receptor, family 8, subfamily B, member 3
chr7_+_138818489 0.037 NM_001144920
NM_001144923
NM_024926
TTC26


tetratricopeptide repeat domain 26


chr3_-_138478184 0.036 NM_006219
PIK3CB
phosphoinositide-3-kinase, catalytic, beta polypeptide
chr4_+_166794409 0.036 NM_001204760
NM_012464
TLL1

tolloid-like 1

chr4_+_95376396 0.036 PDLIM5
PDZ and LIM domain 5
chr4_-_140223611 0.035 NM_001184987
NM_001184988
NM_001184989
NM_001184990
NDUFC1



NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa



chr5_+_150040402 0.033 NM_001122853
NM_133371
MYOZ3

myozenin 3

chr2_+_169659099 0.033 NM_001039724
NM_001171632
NM_052946
NOSTRIN


nitric oxide synthase trafficker


chr2_-_134326030 0.033 NM_207363
NM_207481
NCKAP5

NCK-associated protein 5

chr17_-_7218370 0.033 NM_004489
GPS2
G protein pathway suppressor 2
chr1_-_89664510 0.033 NM_052941
GBP4
guanylate binding protein 4
chr6_+_105404922 0.032 NM_001004317
LIN28B
lin-28 homolog B (C. elegans)
chr7_-_83824216 0.032 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr6_+_30130982 0.032 NM_033229
TRIM15
tripartite motif containing 15
chr22_-_36236421 0.031 NM_001031695
NM_001082576
NM_001082577
NM_014309
RBFOX2



RNA binding protein, fox-1 homolog (C. elegans) 2



chr9_-_34458477 0.031 NM_001184940
NM_001184941
NM_001184942
NM_001184943
NM_001184945
NM_147202
C9orf25





chromosome 9 open reading frame 25





chrX_+_65382432 0.030 NM_138737
HEPH
hephaestin
chrM_+_5513 0.030


chr7_+_39017608 0.030 NM_001166018
NM_007252
POU6F2

POU class 6 homeobox 2

chr6_-_47277645 0.030 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr4_+_102711763 0.029 NM_001127507
NM_017935
BANK1

B-cell scaffold protein with ankyrin repeats 1

chr12_+_123944385 0.029 NM_180699
SNRNP35
small nuclear ribonucleoprotein 35kDa (U11/U12)
chr7_-_64023444 0.029


chrX_-_32173585 0.029 NM_004013
NM_004020
NM_004021
NM_004022
NM_004023
DMD




dystrophin




chr2_-_158182154 0.028 NM_020711
ERMN
ermin, ERM-like protein
chrX_-_117119282 0.028 NM_001168299
KLHL13
kelch-like 13 (Drosophila)
chr10_+_96522457 0.028 NM_000769
CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
chr17_+_3379295 0.028 NM_000049
ASPA
aspartoacylase
chr19_-_49658645 0.028 NM_002152
HRC
histidine rich calcium binding protein
chr19_-_18632886 0.028 NM_006532
ELL
elongation factor RNA polymerase II
chr5_+_150020201 0.028 NM_001109974
NM_007286
SYNPO

synaptopodin

chr3_+_130279177 0.028 NM_001102608
COL6A6
collagen, type VI, alpha 6
chr5_+_147691988 0.027 NM_032566
SPINK7
serine peptidase inhibitor, Kazal type 7 (putative)
chr19_+_24269877 0.027 NM_203282
ZNF254
zinc finger protein 254
chr11_+_124824012 0.027 NM_025004
CCDC15
coiled-coil domain containing 15
chr4_+_41614933 0.027 LIMCH1
LIM and calponin homology domains 1
chr6_-_49712055 0.027 NM_001190986
NM_006061
CRISP3

cysteine-rich secretory protein 3

chr16_+_2653350 0.027 LOC652276
potassium channel tetramerisation domain containing 5 pseudogene
chrX_-_15402469 0.026 NM_004469
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chr11_+_5775922 0.026 NM_001005175
OR52N4
olfactory receptor, family 52, subfamily N, member 4
chr16_+_56817367 0.026 NM_001242796
NUP93
nucleoporin 93kDa
chr8_-_101315457 0.026 NM_015435
RNF19A
ring finger protein 19A
chr10_+_5005453 0.025 NM_001353
AKR1C1
aldo-keto reductase family 1, member C1 (dihydrodiol dehydrogenase 1; 20-alpha (3-alpha)-hydroxysteroid dehydrogenase)
chr19_-_56249739 0.025 NM_176820
NLRP9
NLR family, pyrin domain containing 9
chrX_-_33357725 0.025 NM_000109
DMD
dystrophin
chr20_-_45061554 0.024 ELMO2
engulfment and cell motility 2
chr3_+_189349215 0.024 NM_001114978
NM_001114979
NM_003722
TP63


tumor protein p63


chr1_+_66458389 0.024 NM_001037340
PDE4B
phosphodiesterase 4B, cAMP-specific
chr7_+_141490016 0.024 NM_018980
TAS2R5
taste receptor, type 2, member 5
chr17_-_10372875 0.024 NM_017533
MYH4
myosin, heavy chain 4, skeletal muscle
chr2_+_234526290 0.023 NM_019076
UGT1A8
UDP glucuronosyltransferase 1 family, polypeptide A8
chr1_+_198608216 0.023 PTPRC
protein tyrosine phosphatase, receptor type, C
chr2_+_27799388 0.022 NM_032266
C2orf16
chromosome 2 open reading frame 16
chr14_-_65409445 0.022 NM_002083
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr2_+_204571379 0.022 CD28
CD28 molecule
chrX_+_65382627 0.022 HEPH
hephaestin
chr21_-_36231794 0.021 RUNX1
runt-related transcription factor 1
chr6_+_14117486 0.020 NM_001251901
CD83
CD83 molecule
chr15_-_37391596 0.020 NM_172316
MEIS2
Meis homeobox 2
chr1_+_196743929 0.020 NM_001166624
NM_021023
CFHR3

complement factor H-related 3

chr4_-_68621803 0.020 NM_000406
NM_001012763
GNRHR

gonadotropin-releasing hormone receptor

chr3_-_123339178 0.020 MYLK
myosin light chain kinase
chr2_-_122247903 0.019 CLASP1
cytoplasmic linker associated protein 1
chr1_+_226012974 0.019 NM_000120
EPHX1
epoxide hydrolase 1, microsomal (xenobiotic)
chr4_+_54292035 0.018 FIP1L1
FIP1 like 1 (S. cerevisiae)
chr2_-_179914785 0.018 NM_173648
CCDC141
coiled-coil domain containing 141
chr5_-_24645084 0.018 NM_006727
CDH10
cadherin 10, type 2 (T2-cadherin)
chr1_+_177140062 0.018 FAM5B
family with sequence similarity 5, member B
chr1_+_145663156 0.018 RNF115
ring finger protein 115
chr11_-_3803310 0.018 NUP98
nucleoporin 98kDa
chr1_-_160617042 0.018 NM_003037
SLAMF1
signaling lymphocytic activation molecule family member 1
chr3_-_9885659 0.018 RPUSD3
RNA pseudouridylate synthase domain containing 3
chr15_-_75918718 0.018 NM_001042588
SNUPN
snurportin 1
chr4_-_39523132 0.017 UGDH
UDP-glucose 6-dehydrogenase

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.