Motif ID: REST.p3

Z-value: 0.310


Transcription factors associated with REST.p3:

Gene SymbolEntrez IDGene Name
REST 5978 RE1-silencing transcription factor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
RESThg19_v1_chr4_+_57775150_57775189-0.295.8e-01Click!


Activity profile for motif REST.p3.

activity profile for motif REST.p3


Sorted Z-values histogram for motif REST.p3

Sorted Z-values for motif REST.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of REST.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_51561657 0.177 TRIM9
tripartite motif containing 9
chr20_-_60795270 0.168 NM_007232
HRH3
histamine receptor H3
chr1_-_102462789 0.164 NM_058170
OLFM3
olfactomedin 3
chr1_-_102462371 0.162 OLFM3
olfactomedin 3
chr20_-_62284701 0.153 NM_015894
STMN3
stathmin-like 3
chr19_-_39402797 0.140 NM_001243212
LOC643669
uncharacterized LOC643669
chrX_-_153141398 0.138 NM_000425
NM_001143963
NM_024003
L1CAM


L1 cell adhesion molecule


chr20_+_62328068 0.128 TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chrX_-_153141284 0.117 L1CAM
L1 cell adhesion molecule
chr10_-_102790877 0.101 NM_001195263
NM_024895
PDZD7

PDZ domain containing 7

chr11_+_62380212 0.096 NM_000327
ROM1
retinal outer segment membrane protein 1
chr12_+_175872 0.094 NM_001170738
IQSEC3
IQ motif and Sec7 domain 3
chr14_-_51562044 0.089 TRIM9
tripartite motif containing 9
chr18_+_57567191 0.088 NM_021127
PMAIP1
phorbol-12-myristate-13-acetate-induced protein 1
chr9_+_131038421 0.080 NM_001040011
SWI5
SWI5 recombination repair homolog (yeast)
chrX_-_47479229 0.075 NM_006950
NM_133499
SYN1

synapsin I

chr2_-_42720476 0.074 KCNG3
potassium voltage-gated channel, subfamily G, member 3
chr9_+_131038500 0.070 SWI5
SWI5 recombination repair homolog (yeast)
chr5_-_176037091 0.069 NM_052899
GPRIN1
G protein regulated inducer of neurite outgrowth 1
chr10_+_89419352 0.069 NM_001015880
NM_004670
PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

chr11_-_75141015 0.068 KLHL35
kelch-like 35 (Drosophila)
chr20_+_62328002 0.062 NM_003823
TNFRSF6B
tumor necrosis factor receptor superfamily, member 6b, decoy
chr3_-_48700317 0.061 NM_001407
CELSR3
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr16_+_67686813 0.061 RLTPR
RGD motif, leucine rich repeats, tropomodulin domain and proline-rich containing
chr17_+_30813928 0.054 NM_003885
CDK5R1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr2_-_220083658 0.051 ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr16_+_5008317 0.047 NM_014692
SEC14L5
SEC14-like 5 (S. cerevisiae)
chr2_-_220083394 0.047 ABCB6
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr10_+_73555527 0.046 NM_001171933
NM_001171934
CDH23

cadherin-related 23

chr8_-_93978264 0.043 NM_001191035
NM_001171795
NM_001171796
NM_001171797
NM_001171798
NM_001171799
C8orf83





chromosome 8 open reading frame 83





chr9_-_131038196 0.041 NM_004486
GOLGA2
golgin A2
chr8_-_145752405 0.040 NM_001024678
LRRC24
leucine rich repeat containing 24
chr6_+_43603554 0.039 NM_014628
MAD2L1BP
MAD2L1 binding protein
chr9_-_74061819 0.038 TRPM3
transient receptor potential cation channel, subfamily M, member 3
chrX_+_153237990 0.038 NM_003492
TMEM187
transmembrane protein 187
chr19_-_45926759 0.037 ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr19_-_45926819 0.036 NM_202001
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr10_+_102790984 0.035 NM_030971
SFXN3
sideroflexin 3
chr20_+_44657812 0.034 NM_020708
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr5_+_33936490 0.032 NM_016568
RXFP3
relaxin/insulin-like family peptide receptor 3
chr20_+_44657858 0.031 SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr19_-_3971032 0.030 DAPK3
death-associated protein kinase 3
chr11_+_22359666 0.025 NM_020346
SLC17A6
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
chr8_-_93977715 0.024 NM_001191036
C8orf83
chromosome 8 open reading frame 83
chr14_+_21156922 0.023 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr7_+_145813452 0.023 NM_014141
CNTNAP2
contactin associated protein-like 2
chr8_+_6566153 0.023 AGPAT5
1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
chr15_-_60884615 0.021 NM_134262
RORA
RAR-related orphan receptor A
chr8_+_6565870 0.020 NM_018361
AGPAT5
1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
chr17_-_7218370 0.020 NM_004489
GPS2
G protein pathway suppressor 2
chr12_-_99288502 0.019 NM_001204065
NM_001204079
NM_001204080
NM_001204081
ANKS1B



ankyrin repeat and sterile alpha motif domain containing 1B



chr8_+_6565914 0.019 AGPAT5
1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
chr14_+_93389444 0.019 NM_001275
CHGA
chromogranin A (parathyroid secretory protein 1)
chr19_-_3971089 0.016 DAPK3
death-associated protein kinase 3
chr1_+_171750829 0.015 METTL13
methyltransferase like 13
chr19_-_45737466 0.014 NM_138568
EXOC3L2
exocyst complex component 3-like 2
chr6_+_158957652 0.014 TMEM181
transmembrane protein 181
chr6_+_158957467 0.013 NM_020823
TMEM181
transmembrane protein 181
chr19_-_45927142 0.013 ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr6_+_44238479 0.013 NM_001137560
TMEM151B
transmembrane protein 151B
chr11_-_1769086 0.010 IFITM10
interferon induced transmembrane protein 10
chr1_+_25071906 0.009 CLIC4
chloride intracellular channel 4
chr1_+_171750807 0.009 METTL13
methyltransferase like 13
chr2_-_96810775 0.009 DUSP2
dual specificity phosphatase 2
chr10_-_44880452 0.009 NM_000609
NM_001033886
NM_001178134
NM_199168
CXCL12



chemokine (C-X-C motif) ligand 12



chr1_+_171750760 0.009 NM_001007239
NM_014955
NM_015935
METTL13


methyltransferase like 13


chr1_+_101004456 0.008 GPR88
G protein-coupled receptor 88
chr6_+_43149925 0.008 CUL9
cullin 9
chr11_-_27742224 0.007 NM_001143805
NM_001143806
NM_170732
BDNF


brain-derived neurotrophic factor


chr4_+_158141735 0.007 NM_000826
NM_001083619
NM_001083620
GRIA2


glutamate receptor, ionotropic, AMPA 2


chr11_-_27721179 0.007 NM_170734
BDNF
brain-derived neurotrophic factor
chr5_+_141303366 0.006 NM_001142603
NM_014773
KIAA0141

KIAA0141

chr11_-_134123138 0.006 NM_001037304
NM_001037305
NM_014174
NM_199297
NM_199298
THYN1




thymocyte nuclear protein 1




chr1_-_151689246 0.005 NM_007185
CELF3
CUGBP, Elav-like family member 3
chr18_-_55253785 0.005 NM_000140
NM_001012515
FECH

ferrochelatase

chr11_+_32112607 0.004 RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr10_-_50970321 0.004 NM_001143996
NM_001143997
NM_018245
OGDHL


oxoglutarate dehydrogenase-like


chr4_-_175750377 0.004 NM_001042543
NM_006529
GLRA3

glycine receptor, alpha 3

chr5_+_141303463 0.004 KIAA0141
KIAA0141
chr17_+_80332152 0.004 NM_018949
UTS2R
urotensin 2 receptor
chr1_-_13184325 0.003 NM_001136561
LOC440563
heterogeneous nuclear ribonucleoprotein C-like
chr10_-_102790850 0.003 PDZD7
PDZ domain containing 7
chr1_-_20834516 0.003 MUL1
mitochondrial E3 ubiquitin protein ligase 1
chr1_-_209825797 0.002 NM_000228
LAMB3
laminin, beta 3
chr17_-_79881304 0.002 NM_032711
MAFG
v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
chr12_-_29936685 0.002 NM_001193451
TMTC1
transmembrane and tetratricopeptide repeat containing 1
chr6_+_43149905 0.001 NM_015089
CUL9
cullin 9
chr1_+_154540250 0.001 NM_000748
CHRNB2
cholinergic receptor, nicotinic, beta 2 (neuronal)
chr12_+_71833518 0.000 LGR5
leucine-rich repeat containing G protein-coupled receptor 5

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.