CCDC13

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
CCDC13 FLJ25467 coiled-coil domain containing 13 NM_144719 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

This gene clusters together with a non-coding RNA, specifically a lncRNA. Generally there is no expression in human cells and bat cells, however in Ebola-infected cells, we see very low expression after 23 h of infection. This expression occurs in only a small region of the gene and does not necessarily overlap with the exon structure, but also occurs in some intron regions. Perhaps it is the lncRNA that is being expressed and not the mRNA. Although there is evidence for two intron regions being spliced.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome2 2 2 3 4 32 3 3 3
Read_Max
batR. aegyptiacusTranscriptome NA NA 4 NA NA NA NA 2 5
Read_Max
bat_genomeR. aegyptiacusGenome 2 2 4 0 2 0 0 3 6
DESeq
humanH. sapiensGenome 5.06 16.3 16.89 14.69 13.19 310.24 18.54 9.79 3.17
DESeq
batR. aegyptiacusTranscriptome 1.0 1.0 8.33 1.0 1.0 1.0 1.0 2.65 6.25
DESeq
bat_genomeR. aegyptiacusGenome 1.72 2.74 12.27 0.0 2.23 0.0 0.0 2.38 7.71

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 5.06 14.69 18.54 1.54 1.87 0.34
7h 16.3 13.19 9.79 -0.31 -0.74 -0.43
23h 16.89 310.24 3.17 4.2 -2.41 -6.61

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 5.06 16.3 16.89 1.69 1.74 0.05
Ebov 14.69 13.19 310.24 -0.16 4.4 4.56
Marv 18.54 9.79 3.17 -0.92 -2.55 -1.63

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 1.0 1.0 1.0 0.0 0.0 0.0
7h 1.0 1.0 2.65 0.0 1.41 1.41
23h 8.33 1.0 6.25 -3.06 -0.41 2.64

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 1.0 1.0 8.33 0.0 3.06 3.06
Ebov 1.0 1.0 1.0 0.0 0.0 0.0
Marv 1.0 2.65 6.25 1.41 2.64 1.24