FOSB
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| FOSB | G0S3, GOSB, GOS3, AP-1, MGC42291, DKFZp686C0818 | FBJ murine osteosarcoma viral oncogene homolog B | NM_006732 |  |
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Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.
This gene is only expressed in Ebola infected cells in human cells after 23 h. There was no credible transcript found in bat cells. The first intron contains highly differential expressed fragments (see Section~\refdvg:hg19.dvg.00027 XLOC\_009107).
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 3 | 5 | 5 | 4 | 4 | 253 | 5 | 6 | 4 |
Read_Max |  | R. aegyptiacus | Transcriptome | 4 | 4 | 4 | 3 | 3 | 10 | 2 | 2 | 4 |
Read_Max |  | R. aegyptiacus | Genome | 7 | 4 | 4 | 6 | 6 | 6 | 3 | 4 | 8 |
DESeq | | H. sapiens | Genome | 19.27 | 30.58 | 23.83 | 31.8 | 21.32 | 2417.03 | 30.82 | 38.57 | 27.1 |
DESeq | | R. aegyptiacus | Transcriptome | 13.6 | 14.62 | 18.1 | 4.66 | 8.67 | 24.1 | 5.45 | 10.09 | 9.75 |
DESeq | | R. aegyptiacus | Genome | 29.22 | 8.21 | 27.89 | 34.56 | 18.97 | 52.22 | 19.12 | 12.69 | 28.25 |