IL8
| Name | Synonyms | Full Name | RefSeq ID | Description (.pdf) | IGV-img (humangenome) | Sashimi-img (humangenome) | UCSC-img (humangenome) | IGV-img (batgenome) |
|---|---|---|---|---|---|---|---|---|
| IL8 | hg.goi.00009 |  |
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NONE |
Download all snapshots for IGV, UCSC and Sashimi (zip archive)
Description
The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q.
The gene is rather lowly expressed. In the Ebola infected human cells cells 23 h after infection the expression is three times as large.
Maximum read counts and DESeq normalized read counts for human and bat cell lines
| Source | Species | Mapping on | Mock3h | Mock7h | Mock23h | EBOV3h | EBOV7h | EBOV23h | MARV3h | MARV7h | MARV23h | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Read_Max |  | H. sapiens | Genome | 23 | 15 | 3 | 26 | 18 | 171 | 51 | 30 | 23 |
Read_Max |  | R. aegyptiacus | Transcriptome | 13 | 3 | 5 | 3 | 7 | 7 | 6 | 16 | 5 |
Read_Max |  | R. aegyptiacus | Genome | NA | NA | NA | NA | NA | NA | NA | NA | NA |
DESeq | | H. sapiens | Genome | 92.33 | 64.23 | 10.93 | 154.99 | 64.41 | 837.93 | 181.7 | 86.53 | 123.87 |
DESeq | | R. aegyptiacus | Transcriptome | 28.72 | 7.35 | 11.99 | 7.41 | 19.62 | 16.4 | 12.12 | 20.0 | 10.62 |
DESeq | | R. aegyptiacus | Genome | NA | NA | NA | NA | NA | NA | NA | NA | NA |