FOSL1

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
FOSL1 FRA, FOS-Like Antigen 1,fra-1 FOS-like antigen 1 NM_005438 pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.

The gene FOSL1 is only expressed in human cells cells 23 h after infection with Ebola, but throughout all bat cells datasets.

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\igvfigure{ \beginfigure[H] \centering \includegraphics[width=\textwidth]../../input/holy_folders/hg19.apg.00016/snapshots//hg19.apg.00016_igv.eps % \caption\igv of gene FOSL1. Expression only in Ebola 23 h dataset. % <- say something about the figure here \endfigure }

\sashimifigure{ \beginfigure[H] \centering \includegraphics[width=\textwidth]../../input/holy_folders/hg19.apg.00016/snapshots//hg19.apg.00016_sashimi.eps % \caption\sashimi of gene FOSL1. % <- say something about the figure here \endfigure }

\ucscfigure{ \beginfigure[H] \centering \includegraphics[width=\textwidth]../../input/holy_folders/hg19.apg.00016/snapshots//hg19.apg.00016_ucsc.eps % \caption\ucsc of gene FOSL1. Expression only in Ebola 23 h dataset. % <- say something about the figure here \endfigure }

\setcounterfigure0 \enddocument

Show legend

Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome2 1 2 2 4 23 2 4 5
Read_Max
batR. aegyptiacusTranscriptome 200 236 185 233 225 468 158 234 338
Read_Max
bat_genomeR. aegyptiacusGenome 225 250 167 225 201 286 137 306 374
DESeq
humanH. sapiensGenome 3.03 1.0 4.97 3.28 9.13 173.39 10.65 15.39 35.8
DESeq
batR. aegyptiacusTranscriptome 998.25 1200.97 1176.12 1107.13 1178.22 2332.54 969.91 1000.71 1404.91
DESeq
bat_genomeR. aegyptiacusGenome 1940.5 2015.21 2058.61 2269.24 2099.45 4003.69 1858.85 1808.71 2583.13

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 3.03 3.28 10.65 0.11 1.81 1.7
7h 1.0 9.13 15.39 3.19 3.94 0.75
23h 4.97 173.39 35.8 5.12 2.85 -2.28

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 3.03 1.0 4.97 -1.6 0.71 2.31
Ebov 3.28 9.13 173.39 1.48 5.72 4.25
Marv 10.65 15.39 35.8 0.53 1.75 1.22

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 998.25 1107.13 969.91 0.15 -0.04 -0.19
7h 1200.97 1178.22 1000.71 -0.03 -0.26 -0.24
23h 1176.12 2332.54 1404.91 0.99 0.26 -0.73

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 998.25 1200.97 1176.12 0.27 0.24 -0.03
Ebov 1107.13 1178.22 2332.54 0.09 1.08 0.99
Marv 969.91 1000.71 1404.91 0.05 0.53 0.49