RASGEF1B

NameSynonymsFull NameRefSeq IDDescription (.pdf)IGV-img (humangenome)Sashimi-img (humangenome)UCSC-img (humangenome)IGV-img (batgenome)
RASGEF1B GPIG4, FLJ31695 RasGEF domain family, member 1B NM_152545 pdf

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Description

RASGEF1B (RasGEF domain family, member 1B) is a protein-coding gene. GO annotations related to this gene include Ras guanyl-nucleotide exchange factor activity. An important paralog of this gene is RAPGEFL1.

Low expression. Upregulated in human cells cells 23 h after Ebola infection and almost no expression within bat cells cells 23 h after Ebola infection.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source Species Mapping on Mock3h Mock7h Mock23h EBOV3h EBOV7h EBOV23h MARV3h MARV7h MARV23h
Read_Max
humanH. sapiensGenome5 5 3 6 6 44 4 5 9
Read_Max
batR. aegyptiacusTranscriptome 17 21 7 15 13 4 16 19 13
Read_Max
bat_genomeR. aegyptiacusGenome 21 15 11 18 13 3 14 19 9
DESeq
humanH. sapiensGenome 28.4 26.5 9.94 36.36 22.14 620.8 35.21 24.98 79.29
DESeq
batR. aegyptiacusTranscriptome 139.62 115.37 63.3 98.98 79.85 12.55 125.59 100.15 48.23
DESeq
bat_genomeR. aegyptiacusGenome 230.32 177.06 150.63 203.42 147.33 62.66 212.54 180.0 108.74

Human Condition Comparisons

human Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 28.4 36.36 35.21 0.36 0.31 -0.05
7h 26.5 22.14 24.98 -0.26 -0.09 0.17
23h 9.94 620.8 79.29 5.96 3.0 -2.97

Human Time Point Comparisons

human 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 28.4 26.5 9.94 -0.1 -1.51 -1.41
Ebov 36.36 22.14 620.8 -0.72 4.09 4.81
Marv 35.21 24.98 79.29 -0.5 1.17 1.67

Bat Condition Comparisons

bat Mock EBOV MARV FCMock_EBOV FCMock_MARV FCEBOV_MARV
3h 139.62 98.98 125.59 -0.5 -0.15 0.34
7h 115.37 79.85 100.15 -0.53 -0.2 0.33
23h 63.3 12.55 48.23 -2.33 -0.39 1.94

Bat Time Point Comparisons

bat 3h 7h 23h FC3h_7h FC3h_23h FC7h_23h
Mock 139.62 115.37 63.3 -0.28 -1.14 -0.87
Ebov 98.98 79.85 12.55 -0.31 -2.98 -2.67
Marv 125.59 100.15 48.23 -0.33 -1.38 -1.05