RASGEF1B

Name	Synonyms	Full Name	RefSeq ID	Description (.pdf)	IGV-img (human_genome)	Sashimi-img (human_genome)	UCSC-img (human_genome)	IGV-img (bat_genome)
RASGEF1B	GPIG4, FLJ31695	RasGEF domain family, member 1B	NM_152545	pdf

Download all snapshots for IGV, UCSC and Sashimi (zip archive)

Description

RASGEF1B (RasGEF domain family, member 1B) is a protein-coding gene. GO annotations related to this gene include Ras guanyl-nucleotide exchange factor activity. An important paralog of this gene is RAPGEFL1.

Low expression. Upregulated in human cells cells 23 h after Ebola infection and almost no expression within bat cells cells 23 h after Ebola infection.

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Maximum read counts and DESeq normalized read counts for human and bat cell lines

Source	Species	Mapping on	Mock_3h	Mock_7h	Mock_23h	EBOV_3h	EBOV_7h	EBOV_23h	MARV_3h	MARV_7h	MARV_23h
Read_Max	H. sapiens	Genome	5	5	3	6	6	44	4	5	9
Read_Max	R. aegyptiacus	Transcriptome	17	21	7	15	13	4	16	19	13
Read_Max	R. aegyptiacus	Genome	21	15	11	18	13	3	14	19	9
DESeq	H. sapiens	Genome	28.4	26.5	9.94	36.36	22.14	620.8	35.21	24.98	79.29
DESeq	R. aegyptiacus	Transcriptome	139.62	115.37	63.3	98.98	79.85	12.55	125.59	100.15	48.23
DESeq	R. aegyptiacus	Genome	230.32	177.06	150.63	203.42	147.33	62.66	212.54	180.0	108.74

Human Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	28.4	36.36	35.21	0.36	0.31	-0.05
7h	26.5	22.14	24.98	-0.26	-0.09	0.17
23h	9.94	620.8	79.29	5.96	3.0	-2.97

Human Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	28.4	26.5	9.94	-0.1	-1.51	-1.41
Ebov	36.36	22.14	620.8	-0.72	4.09	4.81
Marv	35.21	24.98	79.29	-0.5	1.17	1.67

Bat Condition Comparisons

	Mock	EBOV	MARV	FC_{Mock_EBOV}	FC_{Mock_MARV}	FC_{EBOV_MARV}
3h	139.62	98.98	125.59	-0.5	-0.15	0.34
7h	115.37	79.85	100.15	-0.53	-0.2	0.33
23h	63.3	12.55	48.23	-2.33	-0.39	1.94

Bat Time Point Comparisons

	3h	7h	23h	FC_{3h_7h}	FC_{3h_23h}	FC_{7h_23h}
Mock	139.62	115.37	63.3	-0.28	-1.14	-0.87
Ebov	98.98	79.85	12.55	-0.31	-2.98	-2.67
Marv	125.59	100.15	48.23	-0.33	-1.38	-1.05

Differential transcriptional responses to Ebola and Marburg virus infection in cells from bats and humans

Supplemental Material